Page last updated: 2024-11-05

tizanidine and Brain Vascular Disorders

tizanidine has been researched along with Brain Vascular Disorders in 3 studies

tizanidine: RN given refers to parent cpd; structure
tizanidine : 2,1,3-Benzothiadiazole substituted at C-4 by a Delta(1)-imidazolin-2-ylamino group and at C-4 by a chloro group. It is an agonist at alpha2-adrenergic receptor sites.

Research Excerpts

ExcerptRelevanceReference
"Thirty patients with old post-stroke spastic hemiparesis took part in the investigation."1.29Mechanisms of tizanidine action on spasticity. ( Georgiev, D; Milanov, I, 1994)
"On the spastic side a reflex with prolonged latencies and durations, as well as with decreased amplitudes and thresholds of both reflex responses was found."1.28Flexor reflex for assessment of common interneurone activity in spasticity. ( Milanov, IG, 1992)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's2 (66.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Milanov, I1
Georgiev, D1
Milanov, IG1
Medici, M1
Pebet, M1
Ciblis, D1

Trials

1 trial available for tizanidine and Brain Vascular Disorders

ArticleYear
A double-blind, long-term study of tizanidine ('Sirdalud') in spasticity due to cerebrovascular lesions.
    Current medical research and opinion, 1989, Volume: 11, Issue:6

    Topics: Adult; Aged; Baclofen; Cerebrovascular Disorders; Clinical Trials as Topic; Clonidine; Double-Blind

1989

Other Studies

2 other studies available for tizanidine and Brain Vascular Disorders

ArticleYear
Mechanisms of tizanidine action on spasticity.
    Acta neurologica Scandinavica, 1994, Volume: 89, Issue:4

    Topics: Adult; Aged; Cerebrovascular Disorders; Clonidine; Electromyography; Female; H-Reflex; Hemiplegia; H

1994
Flexor reflex for assessment of common interneurone activity in spasticity.
    Electromyography and clinical neurophysiology, 1992, Volume: 32, Issue:12

    Topics: Adult; Aged; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Benzodiazepinones; Cerebrovascular Diso

1992