titanium has been researched along with Osteolysis in 309 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (0.65) | 18.7374 |
| 1990's | 40 (12.94) | 18.2507 |
| 2000's | 77 (24.92) | 29.6817 |
| 2010's | 128 (41.42) | 24.3611 |
| 2020's | 62 (20.06) | 2.80 |
| Authors | Studies |
|---|---|
| Ha, YC; Kim, HS; Koo, KH; Lee, SJ; Lee, YK; Park, JW | 1 |
| Chen, Z; Ding, Y; Kuang, M; Li, C; Li, S; Lin, C; Lin, S; Ouyang, Z; Wen, Z; Xue, C | 1 |
| Hu, W; Sun, Y; Yu, Y; Yuan, F; Zhao, F | 1 |
| Diao, L; Liu, M; Liu, X; Mao, Y; Shi, X; Yang, X; Zhang, Y; Zhao, F; Zhou, J | 1 |
| Geng, D; Gu, Y; Li, W; Liang, X; Liu, X; Liu, Y; Peng, X; Tao, Y; Wang, L; Wang, Q; Wang, T; Wu, Z; Xu, Y; Zhang, H; Zhang, W; Zhou, J | 1 |
| Dorodi, O; Ghanbari, N; Jousheghan, SS; Panahi, M; Qoreishi, M | 1 |
| Cao, J; Fu, Y; Gong, A; Li, Y; Liu, L; Ma, X; Wu, Y; Yang, Z; Zhang, G; Zhang, L; Zhao, Y | 1 |
| Gao, X; Ge, J; Geng, D; Xu, L; Zhou, W | 1 |
| Chi, Y; Gao, J; Mao, Y; Song, N; Wu, P; Xu, H; Zhao, Y | 1 |
| Bai, J; Chen, L; Geng, D; Gu, Y; Li, M; Li, W; Liang, X; Liu, X; Tao, Y; Wang, H; Wang, T; Wang, W; Wu, Z; Yang, H; Zhang, W; Zhou, J | 1 |
| Chai, H; Fang, JY; Geng, C; She, C; Xu, W; Zhang, ZH | 1 |
| García González, E; Martínez Villén, G; Rodríguez Nogué, L | 1 |
| Cao, W; Dong, J; Jiang, Q; Lv, Z; Ruan, B; Wang, H; Wang, Y; Zhang, L | 1 |
| Cheng, X; Deng, J; Miao, X; Pan, C; Pan, H; Wang, X | 1 |
| Chen, S; Feng, C; Geng, D; Gu, M; Li, W; Li, Y; Ma, Y; Wang, Z; Xiao, L; Yang, Y | 1 |
| Ding, Y; Gao, L; Li, C; Li, S; Li, X; Lin, S; Luo, W; Wang, X; Wen, Z; Wu, C | 1 |
| Ding, Y; Huang, Y; Li, C; Li, S; Lin, S; Liu, T; Ouyang, Z; Sun, Y; Xu, J; Zeng, G; Zheng, Z | 1 |
| Cheng, Y; Han, Z; He, S; Li, L; Lin, J; Liu, N; Teng, Y; Wu, Y; Yang, H; Zhang, S; Zhao, Z | 1 |
| Chai, H; Geng, D; Huang, Q; Jiao, Z; Sun, C; Wang, S; Xu, W | 1 |
| Du, G; Huang, N; Jiang, J; Kang, J; Ning, B; Sun, Z; Yang, S; Zhang, X; Zhang, Y | 1 |
| Jia, C; Li, H; Li, W; Li, Y; Liu, B; Liu, H; Liu, L; Liu, Y; Liu, Z; Nie, L; Sun, X; Wang, Y; Xu, Z; Yu, R; Yuan, Y; Zhang, P; Zhao, Y | 1 |
| Kang, J; Tan, Y; Xiao, W; Xie, X; Yang, D | 1 |
| Choi, H; Ihn, HJ; Kim, JA; Kim, JE; Lim, S; Moon, J; Park, EK; Yea, K | 1 |
| Cao, L; Chen, X; Li, L; Li, Y; Li, Z; Qiu, W; Su, Z; Zhang, W | 1 |
| Chen, DS; Liu, Y; Liu, ZG; Wang, WP; Xie, YL; Yuan, A; Zhang, C; Zhao, JB | 1 |
| Chen, L; Gu, X; Luo, H; Qu, Y; Si, M; Tong, Z | 1 |
| Bai, J; Ge, G; Geng, D; Lin, J; Wang, L; Wang, Q; Wang, Y; Xu, C; Xu, N; Xu, Y | 1 |
| Cheng, T; Qian, Y; Yang, C; Yuan, X; Zhang, X; Zhu, K | 1 |
| Chai, H; Fang, JY; Geng, C; Huang, Q; Jia, P; Jia, XY; She, C; Xu, W; Zhang, ZH | 1 |
| Deng, F; Fu, T; Fu, X; Hu, X; Huang, J; Ji, P; Jiang, L; Song, J; Wu, X; Xu, L; Yang, Z; Zhang, Z; Zhou, P | 1 |
| Chen, X; Cheng, Y; Fan, B; Wei, X; Yu, S; Zhang, A; Zhang, S; Zhao, H | 1 |
| Chen, Z; Ding, Y; Fang, G; Fu, Y; Kuang, M; Li, C; Li, S; Lin, S; Mao, J; Peng, P; Qin, L; Qiu, J; Wen, Z; Xin, M | 1 |
| Cai, Z; Li, D; Ma, R; Qiu, M; Su, B; Sun, H; Xu, J | 1 |
| Jiang, J; Jiang, S; Li, D; Yang, S | 1 |
| Bai, J; Ge, G; Geng, D; Guo, X; Lin, J; Liu, Y; Qu, Q; Shen, J; Shi, J; Tao, Y; Xu, Y; Yang, H; Yu, B | 1 |
| Liu, W; Qian, Y; Shan, H; Yang, C; Yu, X; Zeng, B; Zhang, X | 1 |
| Chen, J; Hong, D; Lei, X; Li, B; Li, M; Liao, Z; Liu, Q; Yang, H; Yang, Y; Zhang, L; Zhang, Z; Zhu, M | 1 |
| Gao, Y; Ma, H; Shi, J; Sun, C; Zhang, Q; Zhang, W | 1 |
| Chen, HF; Feng, K; Ge, YW; Liu, XL; Liu, ZQ; Mao, YQ; Sun, ZY; Wang, CF; Wang, HW; Yu, DG; Zhang, JW | 1 |
| Bai, J; Geng, D; Guo, X; Lin, J; Liu, Y; Pan, G; Shen, J; Sun, H; Wang, D; Xu, M; Yu, B; Zhang, H | 1 |
| Ding, Y; Guo, D; Guo, H; Huang, J; Li, Y; Lin, S; Liu, P; Liu, Q; Liu, Y; Luo, P; Ma, Y; Mo, G; Qiu, H; Qiu, J; Tang, Y; Wen, Z; Xu, J; Xu, L; Yuan, J; Zhang, S; Zhou, T | 1 |
| Dong, F; Li, H; Lian, Y; Liao, Y; Liu, H; Lu, D; Wang, Y; Wu, J; Zhang, Z | 1 |
| Gang, F; Jiang, L; Lin, J; Liu, Z; Shi, W; Sun, X; Wang, X; Wang, Y; Wei, Y; Xu, N; Zhao, L; Zhu, X | 1 |
| He, F; Lin, J; Yang, H; Zhang, Y; Zhu, X | 1 |
| Gao, XR; Ge, J; Geng, DQ; Li, WY; Xu, L; Zhou, WC | 1 |
| Bai, J; Ge, G; Geng, D; Liang, X; Liu, B; Wang, Q; Wang, W; Wei, M; Xu, Y; Yang, H; Yang, S; Zhang, W; Zheng, K | 1 |
| Ding, X; Feng, W; Kc, A; Liang, J; Liao, S; Lin, X; Liu, Q; Liu, Y; Song, F; Song, H; Su, Y; Wang, Z; Xu, J; Zhao, J | 1 |
| Bai, J; Feng, C; Ge, G; Geng, D; Qin, J; Tang, W; Wang, Z; Wei, M; Xiao, L; Zhang, W; Zhong, M; Zhu, J; Zhu, X | 1 |
| Deng, Z; Fu, G; Jin, J; Li, M; Li, S; Liu, C; Lyu, FJ; Ma, Y; Wang, S; Zheng, Q | 1 |
| Chen, D; Guo, F; Li, Y; Liu, Z; Song, G; Yang, J; Zhang, C | 1 |
| Deng, Z; Fu, G; Jin, J; Li, M; Ma, Y; Wang, S; Wang, Z; Zhang, R; Zheng, Q | 1 |
| García-Cimbrelo, E; García-Rey, E; Saldaña, L; Vallés, G; Vilaboa, N | 1 |
| Geng, T; Guo, H; Jin, Q; Lu, Z; Sun, K; Wang, B; Zhang, L | 1 |
| Huang, Q; Huang, W; Lei, G; Li, Q; Liu, Y; Wu, H; Xiao, J; Yang, M; Yin, Y; Zhou, K | 1 |
| Bai, J; Geng, D; Gu, Y; Shi, J; Tao, Y; Wang, Y; Xiong, L; Xu, Y; Xue, Y; Yang, H; Ye, H | 1 |
| Madsen, F; Petersen, ET; Stilling, M; Søballe, K; Thillemann, JK; Torle, J | 1 |
| Bai, J; Ge, G; Geng, D; Gu, Y; Li, N; Li, X; Sun, H; Wang, W; Wang, Z; Xu, Y; Xue, Y; Zhang, W; Zheng, K; Zhou, J | 1 |
| Chen, J; Liao, Z; Sun, S; You, H; Zhang, L; Zhao, G | 1 |
| Chen, W; Gu, M; Pan, B; Sheng, P; Wu, X; Xian, G; Ye, Y; Zhang, Z; Zheng, L | 1 |
| Ge, G; Geng, D; Jiang, S; Wang, L; Wang, Q; Wang, W; Wang, Y; Xu, N; Xu, Y; Zhao, G; Zheng, D; Zhu, R | 1 |
| He, F; Jin, Z; Lin, J; Lin, W; Liu, A; Shi, W; Su, X; Wu, Y; Yang, H; Zhang, C; Zhang, Q; Zhu, X | 1 |
| Shang, GQ; Wang, P; Wang, YZ; Xiang, S; Xu, H; Zhang, HN | 1 |
| Chen, C; He, J; Hu, S; Jin, Y; Rui, Y; Shi, Q; Sun, J; Xue, Y; Zhang, Y | 1 |
| Li, X; Sun, Y; Wang, J; Yan, L; Zhang, Z; Zhao, S | 1 |
| Hussey, DK; McGrory, BJ | 1 |
| Chughtai, M; Delanois, RE; Gwam, CU; Khlopas, A; Malkani, AL; Mohamed, N; Mont, MA | 1 |
| DiVincenzo, MJ; Frydman, GH; Jennings, SH; Kowaleski, MP; Lai, B; Oura, TJ; Vanderburg, CR | 1 |
| Jiao, Z; Qin, A; Shen, P; Xu, W; Yang, C; Zhang, S; Zheng, J | 1 |
| Fernández-Fernández, R; Gil-Garay, E; Martínez-Miranda, JM | 1 |
| Chen, X; Geng, T; Guo, H; Jin, Q; Sun, S; Wang, B; Zhang, S | 1 |
| Du, Z; Wang, Y; Zhu, Z | 1 |
| Chen, L; Chu, B; Fan, Y; Feng, M; Hong, D; Hong, Z; Li, Z; Lv, H; Yuan, C; Zhang, L; Zhu, M | 1 |
| Chen, Y; Li, B; Li, J; Li, Y; Peng, X; Yuan, X | 1 |
| Jeon, JG; Kim, JE; Kim, JS; Lee, MH; Park, IS; Takanche, JS; Yi, HK | 1 |
| Gao, ZY; Guo, CC; Lv, CY; Wang, CY; Wang, YZ; Xu, H; Yin, ZY; Zhang, HN | 1 |
| Ding, Y; Geng, D; Guo, X; Liu, Y; Shi, J; Wang, L; Wu, X; Xu, Y; Yang, H; Zhou, W | 1 |
| Cai, W; Ding, Y; Fu, G; Li, C; Li, S; Luo, M; Peng, P; Qin, L; Qiu, J; Zhang, C | 1 |
| Pritchett, JW | 1 |
| Feng, W; Huang, H; Li, F; Li, G; Li, J; Liao, S; Liu, Y; Ma, S; Wei, Q; Wei, Y; Yao, J; Zhong, C | 1 |
| Fini, M; Martini, L; Parrilli, A; Sartori, M; Tschon, M; Veronesi, F | 1 |
| Feng, K; Ge, YW; Liu, ZQ; Mao, YQ; Sun, ZY; Yu, DG; Zhu, ZA | 1 |
| Liang, T; Lu, Q; Nong, X; Wei, C; Wei, G; Zhao, J | 1 |
| Ding, Y; Fu, G; Li, C; Li, S; Liu, W; Ouyang, N; Peng, P; Qin, L; Qiu, J; Wu, J | 1 |
| Benazzo, F; Cuzzocrea, F; Ferranti, E; Fioruzzi, A; Ivone, A; Jannelli, E; Vanelli, R | 1 |
| Carmi, Y; Eger, M; Gabet, Y; Hiram-Bab, S; Kohavi, D; Liron, T; Sterer, N | 1 |
| Dai, K; Huang, Y; Tang, J; Yang, F | 1 |
| Feng, WY; Liao, SJ; Lin, XX; Liu, Q; Liu, Y; Ma, ST; Moro, A; Song, FM; Wang, ZY; Xu, J; Zhan, XL; Zhao, JM | 1 |
| Atkins, GJ; Crotti, TN; Findlay, DM; Haynes, DR; Ormsby, RT; Solomon, LB; Yang, D | 1 |
| Awiszus, F; Feuerstein, B; Goldau, G; Hameister, R; Klutzny, M; Lohmann, CH; Singh, G; Stärke, C | 1 |
| Perni, S; Prokopovich, P; Rivera, MC; Sloan, A | 1 |
| Ding, X; Feng, W; Liao, S; Lin, X; Liu, Q; Liu, Y; Ma, S; Song, F; Song, H; Wang, Z; Xu, J; Yao, J; Zhao, J | 1 |
| Chang, L; Li, W; Wang, F; Wang, X | 1 |
| Cai, W; Chen, Z; Ding, Y; Fang, G; Fu, Y; Li, C; Li, S; Lin, S; Mao, J; Peng, P; Qin, L; Qiu, J | 1 |
| Chen, X; Hayball, J; Li, P; Li, W; Li, Y; Liu, L; Qiu, C; Qu, R; Vasilev, K; Wang, W; Yuan, Y; Zhang, Z; Zhao, Y | 1 |
| Cho, HS; Ihn, HJ; Kim, K; Park, EK | 1 |
| Hong, Y; Liao, L; Lin, Y; Liu, Q; Ni, J; Yu, S; Zhang, Z; Zhong, Y | 1 |
| Gong, W; Jia, T; Jiang, Y; Wooley, PH; Yang, SY | 1 |
| Capello, WN; D'Antonio, JA; Naughton, M | 1 |
| Baxter, RM; Connor, PM; Day, JS; Kurtz, SM; Morrey, BF; Ramsey, ML; Steinbeck, MJ | 1 |
| Ding, Y; Guan, ZP; Huang, DS; Huang, JB; Zeng, WK; Zhang, ML | 1 |
| Guo, H; Hao, S; Jin, Q; Ma, X; Sun, S; Yang, X; Yu, B | 1 |
| Fischer, L; Obando-Pereda, GA; Stach-Machado, DR | 1 |
| Agarwal, S; Azam, A; Morgan-Jones, R | 1 |
| Liu, S; Ross, RD; Sena, K; Sumner, DR; Virdi, AS | 1 |
| Dai, K; Fan, Q; Li, H; Liu, X; Ouyang, Z; Qin, A; Qu, X; Tang, T; Tian, B; Wang, W; Wu, C; Xu, X; Zhai, Z | 1 |
| Baad-Hansen, T; Bonefeld, CM; Gustafson, K; Jakobsen, SS; Johansen, JD; Lorenzen, ND; Stilling, M; Søballe, K; Thyssen, JP | 1 |
| Fan, Q; Gu, D; Jiang, C; Li, H; Liu, X; Ouyang, Z; Qin, A; Qu, X; Tang, T; Xiao, F; Zhai, Z | 1 |
| Ellison, P; Grosse, S; Hallan, G; Haugland, HK; Høl, PJ; Lilleng, P | 1 |
| Cui, J; Geng, D; Liu, X; Shao, H; Xu, Y; Yang, H; Yu, L; Zhang, W; Zhu, S | 1 |
| Dai, K; Fan, Q; Jiang, Q; Jiang, T; Li, H; Liu, X; Ouyang, Z; Qin, A; Shao, Z; Tang, T; Tian, B; Yu, Y; Zhai, Z; Zheng, M; Zhu, Z | 1 |
| Aquarius, R; Buma, P; Schreurs, BW; Verdonschot, N; Walschot, LH | 1 |
| Hong, JM; Ihn, HJ; Kim, JA; Kim, SH; Kim, SY; Lim, J; Park, EK; Park, JY; Shin, HI | 1 |
| Ang, ES; Chim, SM; Ding, Y; Feng, H; Huang, J; Liu, Q; Pavlos, N; Tan, RX; Tickner, J; Wu, H; Xu, J; Xue, W; Ye, J; Zhao, J; Zhou, L | 1 |
| Fan, Q; Li, H; Liu, F; Liu, X; Qin, A; Qu, X; Tang, T; Tian, B; Wang, W; Wu, C; Zhai, Z; Zhu, Z | 1 |
| Jiang, C; Liu, X; Mao, Y; Ouyang, Z; Qin, A; Qu, X; Tang, T; Tian, B; Wang, W; Wu, C; Zhai, Z; Zhu, Z | 1 |
| Dai, K; Gu, X; Jiang, C; Liu, X; Qin, A; Tang, T; Wang, J; Wang, W; Wang, Y; Xiao, F; Zhai, Z; Zhu, Z | 1 |
| Chen, D; Guo, F; Hei, C; Jin, Q; Li, P; Li, Y; Lu, Z | 1 |
| Bao, N; Cao, L; Fang, Y; Sun, Y; Wang, B; Wang, Q; Xiong, C; Zhang, Z; Zhao, J | 1 |
| Frydman, A; Simonian, K | 1 |
| Cui, J; Geng, D; Shao, H; Shen, J; Wang, M; Wang, Y; Xu, Y; Yang, H; Zhang, W; Zhu, S | 1 |
| Jang, SP; Kim, DW; Lim, SJ; Moon, YW; Park, YS | 1 |
| Choi, YH; Im, SU; Lee, YE; Park, EK; Park, KS; Song, KB | 1 |
| Chen, S; Fan, SW; Hu, ZJ; Huang, KM; Jin, G; Ma, JJ; Ma, Y; Qin, A; Tang, XZ; Wang, JY; Wang, Q; Zhou, ZJ | 1 |
| Geng, D; Hu, X; Ping, Z; Shao, H; Wang, Y; Wu, J; Xu, Y; Yang, H; Zhang, W; Zhu, S; Zhu, X | 1 |
| Berger, RA; Della Valle, CJ; Jacobs, JJ; Paprosky, WG; Plummer, DR; Sporer, SM | 1 |
| Dong, W; Geng, L; Li, M; Qin, A; Qin, Y; Wang, W; Zhang, M; Zhang, X | 1 |
| Bao, N; Gan, J; Guo, T; Liu, N; Qian, H; Shi, T; Wang, Z; Zhao, J; Zhou, G | 1 |
| Bao, N; Gan, J; Guo, T; Liu, N; Qian, H; Shi, T; Wang, R; Wang, Z; Zhao, J; Zhou, G | 1 |
| Hall, DJ; Jacobs, JJ; Pourzal, R; Skipor, AK; Turner, TM; Urban, RM | 1 |
| Geng, D; Gu, Y; Hu, X; Ping, Z; Shao, H; Wang, L; Wang, Y; Xu, Y; Yang, H; Zhang, W; Zhu, M | 1 |
| Chen, HX; Fan, YY; Feng, MX; Hong, D; Hong, JX; Lei, XH; Qin, A; Wang, Q; Yuan, CT; Zhu, M | 1 |
| Chen, KH; Huang, KC; Hung, LK; Lee, CH; Shih, CM; Su, KC | 1 |
| Einhorn, TA; Liu, AT; Liu, CJ; Tian, QY; Wei, JL; Yi, YS; Zhao, YP | 1 |
| Chen, W; Guo, Y; Li, C; Li, Z; Luo, G; Sheng, P; Wang, H; Wang, Y; Xiao, Y; Zhang, Y; Zhang, Z | 1 |
| Bechtel, CP; Gebhart, JJ; Greenfield, EM; Kiss-Toth, E; Tatro, JM; Wilkinson, JM | 1 |
| Chen, L; Deng, ZL; He, MS; Li, H; Liao, Y; Liu, Y; Wang, C; Wang, Y; Wu, NN; Zhang, RX | 1 |
| Liu, N; Meng, J; Shi, T; Wang, Z; Zhao, J; Zhou, G | 1 |
| Lachiewicz, PF; Soileau, ES | 2 |
| Geng, D; Hu, X; Ping, Z; Shi, J; Tao, Y; Wang, J; Wang, L; Wang, Y; Wu, X; Xu, Y; Yang, H; Zhang, W | 1 |
| Delank, KS; Floerkemeier, T; Frecher, S; Grupp, TM; Jäger, M; Puente Reyna, AL; Schilling, C | 1 |
| Dai, J; He, J; Li, X; Sun, Y; Wang, D; Wang, J; Wang, S; Yan, L; Zhang, Z; Zhao, S | 1 |
| Ding, Y; Huang, DS; Huang, JB; Qin, CQ; Song, B; Zhang, C | 1 |
| He, R; Jiang, S; Xue, D; Ye, C; Yu, Y; Zhang, W; Zhou, X; Zhu, L | 1 |
| Gan, M; Geng, D; Hu, X; Ping, Z; Shi, J; Tao, Y; Wang, L; Wang, Z; Wu, X; Xu, Y; Yang, H; Zhang, W | 1 |
| Bao, N; Deng, Z; Gao, Q; Jin, J; Wang, Y; Wang, Z; Zhao, J | 1 |
| Hasegawa, Y; Higuchi, Y; Ishiguro, N; Komatsu, D; Seki, T | 1 |
| Eger, M; Gabet, Y; Kohavi, D; Liron, T; Sterer, N | 1 |
| Chakraborty, C; Chang, JD; Jagga, S; Lee, DH; Lee, SS; Lee, YH; Nam, JS; Nguyen, LT; Sharma, AR; Sharma, G | 1 |
| Geng, D; Guo, X; Hou, Z; Hu, X; Ping, Z; Shi, J; Tao, Y; Wang, L; Wang, Z; Wu, X; Xu, Y; Yang, H; Zhang, W | 1 |
| Deng, LF; Fan, WS; Guo, CA; Kang, H; Wang, YM; Yan, ZQ; Zhu, L | 1 |
| Bian, Z; He, Q; Li, M; Tian, F; Wang, X; Yao, W; Zhu, L | 1 |
| Bonar, SF; Kirsh, G; Murali, R; Walter, WK; Walter, WL | 1 |
| Hubbard, JB; Lachiewicz, PF; Soileau, ES | 1 |
| Ihle, M; Mai, S; Pfluger, D; Siebert, W | 1 |
| Assini, JB; Biant, LC; Bruce, WJ; Walker, PM; Walsh, WR | 1 |
| Beksaç, B; González Della Valle, A; Salas, A; Salvati, EA | 1 |
| Rahbek, O; Stilling, M; Søballe, K | 1 |
| Bresson, D; Chauvet, D; Chibbaro, S; Di Emidio, P; Galzio, R; George, B; Makiese, O; Mirone, G | 1 |
| Bailey, MJ; Clanchy, FI; De Kok, B; Graves, SE; Hamilton, JA; Haynes, D; Lacey, DC; Speed, K | 1 |
| Bukata, SV; Darowish, M; Flick, LM; Gelinas, J; Huang, W; Li, P; O'Keefe, RJ; Rahman, R; Schwarz, EM | 1 |
| Alanen, K; Kohonen, I; Koivu, H; Sipola, E; Tiusanen, H; Vahlberg, T | 1 |
| Altenburg, AJ; Brown, TD; Callaghan, JJ; Dahl, KA; Goetz, DD; Johnston, RC; Leinen, JA; Liu, SS; Pedersen, DR; Yehyawi, TM | 1 |
| Araki, Y; Harada, H; Kagiya, T; Kimura, S; Narushima, T; Nezu, T; Sasaki, M; Taira, M | 1 |
| Krieg, AH; Ochsner, PE; Speth, BM | 1 |
| Gong, W; Jia, T; Wooley, PH; Yang, SY; Yu, H; Zhang, L; Zhang, T | 1 |
| Galley, MR; Meding, JB; Ritter, MA | 1 |
| Zhang, C; Zhang, P; Zhou, X; Zhu, Z | 1 |
| Geng, D; Wang, J; Wang, X; Xu, Y; Yang, H; Zhu, G; Zhu, X | 1 |
| Cai, XZ; Li, R; Yan, SG; Zhu, FB; Zhu, HX | 1 |
| Asou, Y; Denhardt, DT; Kato, N; Muneta, T; Noda, M; Okawa, A; Okuda, N; Rittling, SR; Shimizu, S; Shinomiya, K; Tsuji, K | 1 |
| Eastell, R; Gordon, A; Greenfield, EM; Kiss-Toth, E; Wilkinson, JM | 1 |
| Lv, D; Sun, ML; Wang, HB; Zhu, L | 1 |
| Forke, L; Irlenbusch, U; Lorenz, U | 1 |
| Hawkins, M; Markel, DC; Ren, W; Shi, T; Zhang, R | 1 |
| Geng, DC; Wang, XB; Xu, YZ; Yang, HL; Zhu, GM; Zhu, XS | 1 |
| Ayers, DC; Chan, M; Finberg, RW; Iwakura, Y; Kurt-Jones, EA; St Pierre, CA | 1 |
| Bourne, RB; Charron, KD; Corten, K; MacDonald, SJ; McCalden, RW; Teo, Y | 1 |
| Belt, EA; Ikävalko, M; Kautiainen, H; Kokkonen, A; Tiihonen, R | 1 |
| Bai, L; McQueen, DA; Song, Z; Wooley, PH; Yang, SY; Yu, H; Zhang, K | 1 |
| Cheng, T; Peng, X; Zhang, W; Zhang, X | 1 |
| Cahir, J; Chirodian, N; Derbyshire, B; Macnair, R; Toms, A; Wimhurst, J; Wynn-Jones, H | 1 |
| Greenfield, EM; Schnaser, EA; Smith, MV; Tatro, JM; Wu, D | 1 |
| Bourne, RB; Brandt, JM; Burnell, CD; Petrak, MJ | 1 |
| Chen, L; Geng, D; Huang, C; Mao, H; Wang, J; Xu, Y; Yang, H; Zhu, X | 1 |
| Hong, JM; Jin, S; Kim, SY; Kim, TH; Park, EK; Park, JY; Shin, HI | 1 |
| Cheng, T; Peng, X; Zhang, W; Zhang, X; Zhao, H | 1 |
| Bader, R; Fritsche, A; Hansmann, D; Jonitz, A; Lochner, K; Mueller, P; Mueller-Hilke, B | 1 |
| Celil Aydemir, AB; Chung, KJ; Hsu, AC; Jacobs, CR; Kim, KO; Lee, FY; Lee, HG; Minematsu, H; Nizami, SA; Shin, MJ | 1 |
| Hasty, KA; Marlar, J; Schwab, LP; Smith, RA | 1 |
| Cheng, T; Mao, X; Pan, X; Zhang, X | 1 |
| Argintar, E; Bush, C; Chen, FH; Haleem-Smith, H; Hampton, D; Lamb, J; Postma, WF; Rimington, T; Tuan, RS | 1 |
| García-Cimbrelo, E; Vallés, G; Vilaboa, N | 1 |
| Cheng, T; Mao, X; Pan, X; Peng, X; Zhang, X; Zhao, S | 1 |
| Beecher, B; Glassner, P; Kwon, YM; Malchau, H | 1 |
| Cao, L; Cheng, TS; Chim, SM; Dai, KR; Lin, Z; Pavlos, NJ; Qin, A; Xu, J; Zheng, MH | 1 |
| Kim, MH; Kim, SY; Kim, TH; Lee, SH; Shin, DK | 1 |
| Ding, Y; Fu, YR; Huang, DS; Qin, CQ; Xu, J | 1 |
| Chen, D; Guo, Y; Mao, X; Zhang, X | 1 |
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| Chen, D; Cheng, T; Guo, Y; Mao, X; Pan, X; Shi, S; Zhang, X | 1 |
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| Goodman, SB; Ma, T; Miyanishi, K; Schurman, DJ; Smith, RL; Trindade, MC | 1 |
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| Akisue, T; Fujishiro, T; Kurosaka, M; Nishikawa, T; Shibanuma, N; Takikawa, S; Yamamoto, T; Yoshiya, S | 1 |
| Goodman, SB; Patel, R; Smith, RL; Trindade, MC; Wong, N; Yaszay, B | 1 |
| Berry, DJ; Jewison, DE; Loer, F; Morrey, BF; Scully, SP; Sibonga, JD; Sprecher, C; von Knoch, M | 1 |
| Anderson, GI; Coles, C; Fang Chen, Y; MacQuarrie, RA | 1 |
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| Fornasier, VL; Goodman, SB; Kamel, M; Protzner, K; Shojaci, A; Song, Y | 1 |
| Epstein, NJ; Goodman, SB; Ma, T; Miyanishi, K; Regula, D; Saket, RR; Smith, RL; Trindade, MC; Warme, BA | 1 |
| Hasegawa, Y; Ishiguro, N; Masui, T; Sakano, S; Warashina, H | 1 |
| Cho, DR; Garrigues, GE; Goldring, SR; Herndon, JH; Rubash, HE; Shanbhag, AS | 1 |
| Goldberg, VM; Greenfield, EM; Nalepka, JL; Rimnac, CM; Taki, N; Tatro, JM; Togawa, D | 1 |
| Anderson, PG; Koetsier, JW; Louwerse, RT; Van Hout, F; Vervest, TM; Wapstra, FH | 1 |
| Gruen, TA; Hanssen, AD; Lewallen, DG; Lewis, RJ; O'Keefe, TJ; Poggie, RA; Stulberg, SD; Sutherland, CJ | 1 |
| Baumann, B; Eulert, J; Jakob, F; Nöth, U; Rader, CP; Rolf, O; Seufert, J | 1 |
| Darowish, M; O'Keefe, RJ; Schwarz, EM; Soloviev, A | 1 |
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| Haleem-Smith, H; Laqueriere, P; Manner, PA; Okafor, CC; Tuan, RS | 1 |
| Cheng, K; Pruitt, L; Ries, MD; Zaloudek, C | 1 |
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| Ivashkiv, LB; Ly, K; Nestor, BJ; Purdue, PE; Rakshit, DS; Sculco, TP; Sengupta, TK | 1 |
| Korovessis, P; Petsinis, G; Repanti, M; Repantis, T | 1 |
| Ivashkiv, LB; Lim, JT; Ly, K; Nestor, BJ; Purdue, PE; Rakshit, DS; Sculco, TP | 1 |
| Kurtz, SM; Manley, MT; Ong, KL | 1 |
| Gál, I; Glant, TT; Jacobs, JJ; Koreny, T; Tunyogi-Csapó, M; Vermes, C | 1 |
| Doerschuk, CM; Goldberg, VM; Greenfield, EM; Islam, AS; Rimnac, CM; Stewart, MC; Taki, N; Tatro, JM | 1 |
| Gosens, T; Groot, D; Leeuwen, NC; Rhee, MV; Teepen, HJ | 1 |
| Goldberg, VM; Greenfield, EM; Lowe, R; Taki, N; Tatro, JM | 1 |
| Schwarzinger, UM; Steindl, MS; Zweymüller, KA | 1 |
| Hasty, KA; Smith, RA; Xing, Z | 1 |
| Greene, AK; McNeely, PD; Mislow, JM; Proctor, MR; Rogers, GF | 1 |
| Berasi, CC; Berend, KR; Lombardi, AV | 1 |
| Bragg, B; Epstein, NJ; Goodman, S; Ma, T; Smith, RL | 1 |
| Bryant, P; Lachiewicz, PF; Soileau, ES | 1 |
| Bierbaum, BE; Bono, JV; Kelly, SJ; Robbins, CE; Ward, DM | 1 |
| Bostrom, MP; Ivashkiv, LB; Koulouvaris, P; Ly, K; Nestor, BJ; Purdue, PE; Sculco, TP | 1 |
| Lee, JA; McCarthy, JC | 1 |
| Schwarzinger, U; Steindl, M; Zweymüller, KA | 1 |
| Gejo, R; Kimura, T; Matsushita, I; Morita, Y | 1 |
| Bell, CG; Crawford, R; Pickering, SA; Sydney, SE | 1 |
| Barrack, RL; Ezzet, KA; Garcia, R | 1 |
| Galante, JO; Glant, TT; Hoerrner, LA; Hutchinson, NI; Jacobs, JJ; Kuettner, KE; Lark, MW; Mikecz, K; Yao, J | 1 |
| Stiles, PJ; Unwin, AJ | 1 |
| Chiba, J; Kim, KJ; Rubash, HE | 1 |
| Fox, GM; Heiner, JP; McBeath, AA | 1 |
| Amstutz, HC; Grecula, M; Guttmann, D; Schmalzried, TP | 1 |
| Berry, DJ; Rand, JA; Wold, LE | 1 |
| Bloebaum, RD; Dupont, JA | 1 |
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| Beebe, JD; DeHeer, DH; Kane, KR; Owens, SR; Swanson, AB | 1 |
| Maloney, WJ; Woolson, ST | 1 |
| Gustilo, RB; Tsukayama, DT; Wang, JY; Wicklund, BH | 2 |
| Eng, K; Hozack, WJ; Mesa, J; Rothman, RH | 1 |
| Faris, PM; Herbst, SA; Keating, EM; Meding, JB; Ritter, MA | 1 |
| Brennan, FR; Glant, TT; Jacobs, JJ; Lee, SH; Ragasa, DR; Urban, RM | 1 |
| Betts, F; Doty, SB; Evans, BG; Salvati, EA | 1 |
| Coldham, G; Devane, PA; Horne, JG; Krause, B; Martin, K | 1 |
| Bourne, RB; Mulliken, BD; Nayak, N; Rorabeck, CH | 2 |
| Bourne, RB; Devane, PA; Horne, JG; Nayak, NN; Robinson, EJ; Rorabeck, CH | 1 |
| Engh, CA; Engh, GA; Moore, KD; Vinh, TN | 1 |
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| Aspenberg, P; de Kleine, R; Tigchelaar, W; van der Vis, H; van Noorden, CJ | 1 |
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| Herrington, SM; Lombardi, AV; Mallory, TH; Staab, M | 1 |
| Frech, W; Herberts, P; Kärrholm, J; Malchau, H; Nivbrant, B; Snorrason, F | 1 |
| Chun, LE; Goodman, SB; Maloney, WJ; Nakashima, Y; Schurman, DJ; Smith, RL; Song, Y; Sun, DH; Trindade, MC | 1 |
| Beight, J; Cautilli, GP; Hozack, WJ; Yao, B | 1 |
| Hallikainen, D; Helevirta, P; Peltoniemi, HH; Toivonen, T; Waris, T | 1 |
| Amstutz, HC; Brown, IC; Engh, CA; Harris, WH; Schmalzried, TP | 1 |
| Campbell, P; Ebramzadeh, E; Llinás, A; McKellop, HA; Park, SH; Sarmiento, A | 1 |
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| Bookman, I; Davey, JR; Kreder, HK; Yee, AJ | 1 |
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| Beals, N; Bearcroff, J; Lalor, PA; Mitchell, SL; Namba, R; Sledge, CB; Spector, M | 1 |
| Benz, EB; Goater, JJ; Kollias, G; Lu, AP; O'Keefe, RJ; Puzas, JE; Rosier, RN; Schwarz, EM | 1 |
| Eggli, S; Ganz, R; Schöll, E | 1 |
| Ando, M; Baba, H; Dai, X; Hashimoto, N; Oki, H; Okumura, Y; Omori, H | 1 |
| Childs, LM; Goater, JJ; O'Keefe, RJ; Schwarz, EM | 1 |
| Chandrasekaran, R; Galante, JO; Glant, TT; Jacobs, JJ; Roebuck, KA; Vermes, C | 1 |
| Boyce, BF; Langenbach, R; Morham, SG; O'Keefe, RJ; Puzas, EJ; Rosier, RN; Schwarz, EM; Xing, L; Young, DA; Zhang, X | 1 |
| Bi, Y; Carter, JR; Goldberg, VM; Greenfield, EM; Jinno, T; Kaar, SG; Kaye, SJ; Kilic, BA; Ragab, AA; Stewart, MC | 1 |
| Andrews, M; Fisher, J; Ingham, E; Ivory, J; Mcgrath, LR; Shardlow, DL; Stone, MH | 1 |
| Anderson, D; Boskey, AL; Boyce, BF; Childs, LM; Dougall, WC; O'Keefe, RJ; Paschalis, EP; Puzas, JE; Rosier, RN; Schwarz, EM; Xing, L | 1 |
| Hernández Cortés, P; Hernández Hernández, MA; Mesa Ramos, F; Nájera Sagastume, OO; Pajares López, M | 1 |
| Goater, JJ; O'Keefe, RJ; Puzas, JE; Rosier, RN; Schwarz, EM | 1 |
| Latta, LL; Sarmiento, A; Tarr, RR; Zych, GA | 1 |
| Bansal, M; Brien, W; Buly, RL; Huo, MH; Salvati, E | 1 |
| Harris, WH | 1 |
| Bloebaum, R; Dorr, LD; Emmanual, J; Meldrum, R | 1 |
| Amstutz, HC; Campbell, PA; Kilgus, D; Kossovsky, N; Nasser, S | 1 |
| Drouillard, P; Lombardi, AV; Mallory, TH; Vaughn, BK | 1 |
6 review(s) available for titanium and Osteolysis
| Article | Year |
|---|---|
Involvement of NF-κB/NLRP3 axis in the progression of aseptic loosening of total joint arthroplasties: a review of molecular mechanisms.
Topics: Arthroplasty; Cytokines; Humans; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Osteoclasts; Osteolysis; Titanium | 2022 |
Titanium particles in peri-implantitis: distribution, pathogenesis and prospects.
Topics: Dental Implants; Humans; Inflammation; Osteolysis; Peri-Implantitis; Titanium | 2023 |
Review of models for titanium as a foreign body.
Topics: Dental Implants; Dental Materials; Dental Restoration Failure; Foreign Bodies; Foreign-Body Reaction; Humans; Hypersensitivity; Osteolysis; Solubility; Titanium | 2014 |
Periprosthetic osteolysis: genetics, mechanisms and potential therapeutic interventions.
Topics: Adaptive Immunity; Animals; Arthroplasty, Replacement; Bone Resorption; Humans; Joint Prosthesis; Osteogenesis; Osteolysis; Polymethyl Methacrylate; Prosthesis Failure; Titanium | 2012 |
Particulate debris in cemented total hip replacement.
Topics: Biocompatible Materials; Bone Cements; Chromium Alloys; Hip Prosthesis; Humans; Macrophages; Metals; Osteolysis; Particle Size; Polyethylenes; Prosthesis Design; Prosthesis Failure; Synovial Fluid; Titanium | 1994 |
Biological reactions to wear debris in total joint replacement.
Topics: Biocompatible Materials; Bone Cements; Ceramics; Cytokines; Foreign Bodies; Hip Joint; Hip Prosthesis; Humans; Macrophages; Metals; Osteolysis; Particle Size; Polyethylenes; Polymethyl Methacrylate; Prosthesis Failure; Titanium | 2000 |
7 trial(s) available for titanium and Osteolysis
| Article | Year |
|---|---|
Less polyethylene wear in monobloc compared to modular ultra-high-molecular-weight-polyethylene inlays in hybrid total knee arthroplasty: A 5-year randomized radiostereometry study.
Topics: Adult; Aged; Arthroplasty, Replacement, Knee; Bone Screws; Female; Follow-Up Studies; Humans; Knee Prosthesis; Male; Middle Aged; Osteoarthritis, Knee; Osteolysis; Polyethylenes; Prospective Studies; Prosthesis Design; Radiostereometric Analysis; Tibia; Titanium | 2021 |
Metal release and metal allergy after total hip replacement with resurfacing versus conventional hybrid prosthesis.
Topics: Arthroplasty, Replacement, Hip; Chromium; Cobalt; Female; Follow-Up Studies; Hip Prosthesis; Humans; Hypersensitivity; Lymphocyte Activation; Male; Metals; Middle Aged; Nanoparticles; Osteolysis; Patch Tests; Polyethylene; Prosthesis Failure; Surveys and Questionnaires; Titanium | 2014 |
Polyethylene wear and osteolysis with a new modular titanium acetabular component: results at 7 to 13 years.
Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Biocompatible Materials; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prospective Studies; Prosthesis Failure; Titanium; Young Adult | 2008 |
Inferior survival of hydroxyapatite versus titanium-coated cups at 15 years.
Topics: Aged; Arthroplasty, Replacement, Hip; Coated Materials, Biocompatible; Durapatite; Equipment Safety; Female; Follow-Up Studies; Hip Prosthesis; Humans; Joint Instability; Kaplan-Meier Estimate; Male; Materials Testing; Middle Aged; Osteoarthritis, Hip; Osteolysis; Probability; Prospective Studies; Prosthesis Design; Prosthesis Failure; Risk Assessment; Statistics, Nonparametric; Time Factors; Titanium; Treatment Outcome | 2009 |
A comparison of cemented and cementless titanium femoral components used for primary total hip arthroplasty: a radiographic and survivorship study.
Topics: Acetabulum; Arthroplasty, Replacement, Hip; Cementation; Equipment Failure Analysis; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Osteolysis; Prosthesis Design; Reoperation; Titanium | 2002 |
Measurement of polyethylene wear in acetabular components inserted with and without cement. A randomized trial.
Topics: Acetabulum; Adult; Aged; Bone Cements; Computer Simulation; Double-Blind Method; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Image Processing, Computer-Assisted; Male; Materials Testing; Middle Aged; Models, Anatomic; Osteoarthritis, Hip; Osteolysis; Polyethylenes; Prospective Studies; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium | 1997 |
A randomized trial of hydroxyapatite coated prostheses in total hip arthroplasty.
Topics: Acetabulum; Age Factors; Aged; Alloys; Arthroplasty, Replacement, Hip; Biocompatible Materials; Coated Materials, Biocompatible; Durapatite; Female; Femur; Follow-Up Studies; Foreign-Body Migration; Hip Prosthesis; Humans; Hyperostosis; Linear Models; Male; Middle Aged; Osteolysis; Porosity; Prospective Studies; Prosthesis Design; Radiography; Sex Factors; Surface Properties; Titanium | 1999 |
296 other study(ies) available for titanium and Osteolysis
| Article | Year |
|---|---|
High Risk of Neck-liner Impingement and Notching Observed with Thick Femoral Neck Implants in Ceramic-on-ceramic THA.
Topics: Adult; Arthroplasty, Replacement, Hip; Ceramics; Femur Neck; Hip Joint; Hip Prosthesis; Humans; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Reproducibility of Results; Retrospective Studies; Titanium; Treatment Outcome | 2022 |
LncRNA Neat1 promotes the macrophage inflammatory response and acts as a therapeutic target in titanium particle-induced osteolysis.
Topics: Animals; Inflammation; Joint Prosthesis; Macrophages; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; RNA, Long Noncoding; Titanium | 2022 |
MiR-25 overexpression inhibits titanium particle-induced osteoclast differentiation via down-regulation of mitochondrial calcium uniporter in vitro.
Topics: Calcium; Calcium Channels; Cell Differentiation; Down-Regulation; Humans; MicroRNAs; Osteoclasts; Osteolysis; RANK Ligand; RNA, Messenger; Titanium | 2022 |
Piperlongumine Inhibits Titanium Particles-Induced Osteolysis, Osteoclast Formation, and RANKL-Induced Signaling Pathways.
Topics: Animals; Bone Resorption; Dioxolanes; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Signal Transduction; Titanium | 2022 |
GSK-3β suppression upregulates Gli1 to alleviate osteogenesis inhibition in titanium nanoparticle-induced osteolysis.
Topics: Glycogen Synthase Kinase 3 beta; Hedgehog Proteins; Humans; Nanoparticles; Osteogenesis; Osteolysis; Titanium; Zinc Finger Protein GLI1 | 2022 |
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
Topics: Animals; Caspase 3; Mice; Mice, Inbred C57BL; Neuropeptides; Osteoblasts; Osteoclasts; Osteolysis; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Titanium | 2022 |
IL-10 inhibits osteoclast differentiation and osteolysis through MEG3/IRF8 pathway.
Topics: Animals; Cell Differentiation; Interferon Regulatory Factors; Interleukin-10; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Polymethyl Methacrylate; Prosthesis Failure; RANK Ligand; RNA; RNA, Long Noncoding; Signal Transduction; Titanium | 2022 |
LY450139 Inhibited Ti-Particle-Induced Bone Dissolution via Suppressing Notch and NF-κB Signaling Pathways.
Topics: Alanine; Animals; Azepines; Bone Resorption; Disease Models, Animal; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Signal Transduction; Solubility; Titanium | 2022 |
NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway.
Topics: Animals; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; Nanoparticles; NF-E2-Related Factor 2; Osteogenesis; Osteolysis; Reactive Oxygen Species; Signal Transduction; Titanium | 2022 |
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact.
Topics: Adaptor Proteins, Signal Transducing; Cell Differentiation; Connexin 43; Interleukin-6; Osteoblasts; Osteocytes; Osteolysis; Titanium; Tumor Necrosis Factor-alpha | 2022 |
Postoperative assessment and management of metallosis and periprosthetic osteolysis in patients treated with metal-on-polyethylene total wrist prostheses.
Topics: Chromium; Cobalt; Humans; Metals; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Titanium; Wrist | 2022 |
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
Topics: Animals; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Osteoclasts; Osteolysis; Prostheses and Implants; Titanium | 2022 |
Bimetallic Metal-Organic Framework for Mitigating Aseptic Osteolysis.
Topics: Humans; Macrophages; Metal-Organic Frameworks; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Reactive Oxygen Species; Titanium | 2023 |
The Dopamine D1 Receptor Attenuates Titanium Particle-Induced Inhibition of Osteogenesis by Activating the Wnt Signaling Pathway.
Topics: Dopamine; Humans; Osteoclasts; Osteogenesis; Osteolysis; Receptors, Dopamine D1; Titanium; Wnt Signaling Pathway | 2023 |
HUCMSC-derived Exosomes Suppress the Titanium Particles-induced Osteolysis in Mice through Inhibiting CCL2 and CCL3.
Topics: Animals; Chemokine CCL2; Chemokine CCL3; Exosomes; Humans; Mice; Osteolysis; Titanium | 2023 |
STING/TBK1 Regulates Inflammation in Macrophages and Titanium Particles-Induced Osteolysis.
Topics: Animals; Inflammation; Macrophages; Mice; NF-kappa B; Osteolysis; Titanium | 2023 |
Quercetin alleviates nanoparticle-induced osteolysis
Topics: Animals; Humans; Inflammasomes; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Pyroptosis; Quercetin; Reactive Oxygen Species; Titanium | 2023 |
Osteocytes Exposed to Titanium Particles Inhibit Osteoblastic Cell Differentiation via Connexin 43.
Topics: Animals; beta Catenin; Cell Differentiation; Connexin 43; Mice; Osteoblasts; Osteocytes; Osteolysis; Titanium | 2023 |
CD73 inhibits titanium particle-associated aseptic loosening by alternating activation of macrophages.
Topics: 5'-Nucleotidase; Adenosine; Humans; Inflammation; Macrophages; Osteolysis; Titanium | 2023 |
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
Topics: 3T3 Cells; Animals; beta Catenin; Inflammasomes; Inflammation; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; Reactive Oxygen Species; Selenomethionine; Signal Transduction; Titanium | 2023 |
Zingerone attenuates Ti particle-induced inflammatory osteolysis by suppressing the NF-κB signaling pathway in osteoclasts.
Topics: Humans; NF-kappa B; Osteoclasts; Osteolysis; Signal Transduction; Titanium | 2023 |
Britanin inhibits titanium wear particle‑induced osteolysis and osteoclastogenesis.
Topics: Actin Cytoskeleton; Animals; Disease Models, Animal; Humans; Mice; Osteoclasts; Osteogenesis; Osteolysis; Titanium | 2023 |
Kaempferol prevents aseptic loosening via enhance the Wnt/β-catenin signaling pathway in vitro and in vivo.
Topics: Animals; beta Catenin; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Kaempferols; Mice; Osteogenesis; Osteolysis; Prospective Studies; Titanium; Wnt Signaling Pathway | 2023 |
The JNK signaling pathway against titanium-particle-induced osteoclastogenesis and bone resorption in vivo.
Topics: Animals; Bone Resorption; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Titanium | 2023 |
Inhibition of protein phosphatase 2A attenuates titanium-particle induced suppression of bone formation.
Topics: 3T3 Cells; Animals; beta Catenin; Cell Differentiation; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Okadaic Acid; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Protein Phosphatase 2; Skull; Titanium; Wnt Signaling Pathway | 2020 |
Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo.
Topics: Actins; Animals; Bone Resorption; Cell Death; Cell Differentiation; Cell Polarity; Curcumin; Cytokines; Immunomodulation; Macrophages; Male; Mice; Mice, Inbred C57BL; Models, Biological; Nanoparticles; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium; Up-Regulation | 2020 |
Reduction of SOST gene promotes bone formation through the Wnt/β-catenin signalling pathway and compensates particle-induced osteolysis.
Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; beta Catenin; Bone Regeneration; Cell Differentiation; Mice; Osteoblasts; Osteoclasts; Osteocytes; Osteogenesis; Osteolysis; Skull; Titanium; Wnt Signaling Pathway | 2020 |
Nanosized Alumina Particle and Proteasome Inhibitor Bortezomib Prevented inflammation and Osteolysis Induced by Titanium Particle via Autophagy and NF-κB Signaling.
Topics: Aluminum Oxide; Animals; Autophagy; Bortezomib; Cell Line; Cytokines; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Nanoparticles; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Proteasome Inhibitors; Signal Transduction; Titanium | 2020 |
DAPT inhibits titanium particle-induced osteolysis by suppressing the RANKL/Notch2 signaling pathway.
Topics: Amyloid Precursor Protein Secretases; Animals; Cells, Cultured; Diamines; Enzyme Inhibitors; Mice, Inbred C57BL; Osteolysis; Prostheses and Implants; RANK Ligand; Receptor, Notch2; Signal Transduction; Thiazoles; Titanium | 2020 |
ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.
Topics: Aged; Aged, 80 and over; Animals; Arthroplasty, Replacement, Hip; Cells, Cultured; Cytokines; Female; Hip Prosthesis; Humans; Macrophages; Male; Mice, Inbred C57BL; Mice, Nude; Middle Aged; NF-kappa B; Osteolysis; Prosthesis Failure; Reoperation; Skull; Synovial Membrane; Titanium; Transcription Factors | 2020 |
Exosomal lncRNAs NONMMUT000375.2 and NONMMUT071578.2 derived from titanium particle treated RAW264.7 cells regulate osteogenic differentiation of MC3T3-E1 cells.
Topics: Animals; Biocompatible Materials; Cell Line; Exosomes; Mice; Osteoclasts; Osteogenesis; Osteolysis; RAW 264.7 Cells; RNA, Long Noncoding; Titanium | 2020 |
[Establishment of artificial joint aseptic loosening mouse model by cobalt-chromium particles stimulation].
Topics: Animals; Chromium; Cobalt; Male; Mice; Mice, SCID; Osteolysis; Prosthesis Failure; Titanium | 2020 |
MiR-106b inhibition suppresses inflammatory bone destruction of wear debris-induced periprosthetic osteolysis in rats.
Topics: Animals; Bone and Bones; Bone Resorption; Cell Count; Cell Polarity; Cytokines; Inflammation; Kidney; Liver; Macrophages; Male; MicroRNAs; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Phosphatidylinositol 3-Kinases; Prostheses and Implants; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RANK Ligand; Rats, Sprague-Dawley; Signal Transduction; Titanium | 2020 |
Naringin inhibits titanium particles-induced up-regulation of TNF-α and IL-6 via the p38 MAPK pathway in fibroblasts from hip periprosthetic membrane.
Topics: Fibroblasts; Flavanones; Humans; Interleukin-6; NF-kappa B; Osteoclasts; Osteolysis; p38 Mitogen-Activated Protein Kinases; Titanium; Tumor Necrosis Factor-alpha; Up-Regulation | 2021 |
Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade.
Topics: Animals; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Gene Knock-In Techniques; Hedgehog Proteins; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Mice; Mice, Inbred C57BL; Morpholines; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proto-Oncogene Proteins c-fos; Purines; Rabbits; Repressor Proteins; Signal Transduction; Titanium | 2020 |
Enalapril inhibits inflammatory osteolysis induced by wear debris in a mouse model.
Topics: Animals; China; Disease Models, Animal; Enalapril; Female; Inflammation; Mice; Mice, Inbred BALB C; Osteoclasts; Osteolysis; Prostheses and Implants; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2020 |
The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo.
Topics: Actins; Animals; Bone Resorption; Cell Differentiation; Ephrin-B2; Female; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Mice, Inbred C57BL; NFATC Transcription Factors; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Proto-Oncogene Proteins c-fos; RANK Ligand; Receptor, EphB4; Recombinant Proteins; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha | 2020 |
Efficient Inhibition of Wear-Debris-Induced Osteolysis by Surface Biomimetic Engineering of Titanium Implant with a Mussel-Derived Integrin-Targeting Peptide.
Topics: Animals; Biomimetic Materials; Bivalvia; Catechols; Cells, Cultured; Coated Materials, Biocompatible; Femur; Integrin alphaVbeta3; Joint Prosthesis; Macrophages; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Osteogenesis; Osteolysis; RANK Ligand; Rats, Sprague-Dawley; Titanium | 2019 |
Carnosol suppresses RANKL-induced osteoclastogenesis and attenuates titanium particles-induced osteolysis.
Topics: Abietanes; Animals; Bone Resorption; Calcium Signaling; Female; Gene Expression Regulation; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proteolysis; RANK Ligand; Skull; Titanium | 2021 |
5-Aza-2-deoxycytidine inhibits osteolysis induced by titanium particles by regulating RANKL/OPG ratio.
Topics: Animals; Base Sequence; Blotting, Western; CpG Islands; Decitabine; DNA Methylation; Gene Expression; Male; Mice, Inbred BALB C; Osteolysis; Osteoprotegerin; Particle Size; RANK Ligand; Reverse Transcriptase Polymerase Chain Reaction; Skull; Titanium; X-Ray Microtomography | 2020 |
Dual directions to address the problem of aseptic loosening via electrospun PLGA @ aspirin nanofiber coatings on titanium.
Topics: Aspirin; Humans; Nanofibers; Osteogenesis; Osteolysis; Titanium | 2020 |
Melatonin suppresses Ti-particle-induced inflammatory osteolysis via activation of the Nrf2/Catalase signaling pathway.
Topics: Actins; Animals; Bone Marrow Cells; Catalase; Cathepsin K; Cell Differentiation; Cells, Cultured; Inflammation; Male; Melatonin; Mice, Inbred C57BL; Monocytes; NF-E2-Related Factor 2; Osteoclasts; Osteogenesis; Osteolysis; Receptors, Cell Surface; Signal Transduction; Skull; Tartrate-Resistant Acid Phosphatase; Titanium | 2020 |
miR-34a carried by adipocyte exosomes inhibits the polarization of M1 macrophages in mouse osteolysis model.
Topics: 3T3 Cells; Adipocytes; Animals; Cell Polarity; Exosomes; Genetic Therapy; Macrophages; Mice; MicroRNAs; Nanoparticles; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; RAW 264.7 Cells; Titanium; Up-Regulation | 2021 |
Punicalagin ameliorates wear-particle-induced inflammatory bone destruction by bi-directional regulation of osteoblastic formation and osteoclastic resorption.
Topics: Animals; Bone Resorption; Hydrolyzable Tannins; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Titanium | 2020 |
Inhibitory effects of biochanin A on titanium particle-induced osteoclast activation and inflammatory bone resorption via NF-κB and MAPK pathways.
Topics: Animals; Arthroplasty, Replacement; Bone Resorption; Cell Line; Durapatite; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Developmental; Genistein; Humans; Inflammation; Interleukin-1alpha; Interleukin-1beta; Mice; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; Osteoporosis; Prostheses and Implants; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha | 2021 |
Puerarin inhibits titanium particle-induced osteolysis and RANKL-induced osteoclastogenesis via suppression of the NF-κB signaling pathway.
Topics: Actins; Animals; Bone Resorption; Cytokines; Gene Expression Regulation; Inflammation Mediators; Isoflavones; Male; Mice; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Rats, Sprague-Dawley; RAW 264.7 Cells; Signal Transduction; Titanium | 2020 |
A Modified Murine Calvarial Osteolysis Model Exposed to Ti Particles in Aseptic Loosening.
Topics: Animals; Arthroplasty, Replacement; Disease Models, Animal; Mice, Inbred C57BL; Osteolysis; Prosthesis Failure; Skull; Spectrometry, X-Ray Emission; Titanium; X-Ray Diffraction; X-Ray Microtomography | 2020 |
Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-
Topics: Animals; Anti-Inflammatory Agents; Benzylisoquinolines; Bone Resorption; Calcium Signaling; Cells, Cultured; Cytokines; Humans; Mice; NF-kappa B; Osteoclasts; Osteolysis; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium | 2020 |
STAT3/IL-6 dependent induction of inflammatory response in osteoblast and osteoclast formation in nanoscale wear particle-induced aseptic prosthesis loosening.
Topics: Animals; Interleukin-6; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteolysis; Prosthesis Failure; Titanium | 2021 |
Wear of hip prostheses increases serum IGFBP-1 levels in patients with aseptic loosening.
Topics: Aged; Arthroplasty, Replacement, Hip; Enzyme-Linked Immunosorbent Assay; Female; Hip Prosthesis; Humans; In Vitro Techniques; Insulin-Like Growth Factor Binding Protein 1; Macrophages; Male; Osteoblasts; Osteolysis; Prosthesis Failure; Reoperation; Titanium | 2021 |
The effect of strontium ranelate on titanium particle-induced periprosthetic osteolysis regulated by WNT/β-catenin signaling in vivo and in vitro.
Topics: 3T3 Cells; Animals; Apoptosis; beta Catenin; Culture Media, Conditioned; Female; In Vitro Techniques; Mice; Mice, Inbred C57BL; Osteoblasts; Osteolysis; Prostheses and Implants; RAW 264.7 Cells; Thiophenes; Titanium; Wnt Signaling Pathway | 2021 |
MgO Nanoparticles Protect against Titanium Particle-Induced Osteolysis in a Mouse Model Because of Their Positive Immunomodulatory Effect.
Topics: Animals; Magnesium Oxide; Mice; Mice, Inbred C57BL; Nanoparticles; Osteolysis; Titanium | 2020 |
Inhibitory effect of acetyl-11-keto-β-boswellic acid on titanium particle-induced bone loss by abrogating osteoclast formation and downregulating the ERK signaling pathway.
Topics: Animals; Bone Density Conservation Agents; Down-Regulation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RAW 264.7 Cells; Skull; Titanium; Triterpenes | 2021 |
Inhibition of Sirtuin 3 prevents titanium particle-induced bone resorption and osteoclastsogenesis via suppressing ERK and JNK signaling.
Topics: Animals; Bone Resorption; Bone-Implant Interface; Cell Differentiation; Cells, Cultured; Drug Discovery; Extracellular Signal-Regulated MAP Kinases; Interleukins; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Nerve Tissue Proteins; NFATC Transcription Factors; Osteoclasts; Osteolysis; RANK Ligand; Sirtuin 3; Titanium | 2021 |
Inhibition of osteoclastogenesis by histone deacetylase inhibitor Quisinostat protects mice against titanium particle-induced bone loss.
Topics: Actins; Animals; Bone Resorption; Cells, Cultured; Disease Models, Animal; Histone Deacetylase Inhibitors; Hydroxamic Acids; Macrophages; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Prostheses and Implants; Proto-Oncogene Proteins c-fos; Signal Transduction; Skull; Titanium | 2021 |
Autophagy inhibitors 3-MA and LY294002 repress osteoclastogenesis and titanium particle-stimulated osteolysis.
Topics: Animals; Autophagy; Chromones; Humans; Mice; Mice, Inbred C57BL; Morpholines; Osteoclasts; Osteogenesis; Osteolysis; Titanium | 2021 |
Harmine Alleviates Titanium Particle-Induced Inflammatory Bone Destruction by Immunomodulatory Effect on the Macrophage Polarization and Subsequent Osteogenic Differentiation.
Topics: Animals; Biomarkers; Bone Diseases; Cell Survival; Disease Models, Animal; Fluorescent Antibody Technique; Harmine; Immunohistochemistry; Inflammation; Macrophage Activation; Macrophages; Male; Mice; Nitric Oxide; Osteoclasts; Osteogenesis; Osteolysis; RAW 264.7 Cells; Titanium; X-Ray Microtomography | 2021 |
Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.
Topics: Animals; Butyrates; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Homeostasis; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanoparticles; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; Receptors, G-Protein-Coupled; RNA, Ribosomal, 16S; Signal Transduction; Titanium | 2021 |
Zoledronic acid and teriparatide have a complementary therapeutic effect on aseptic loosening in a rabbit model.
Topics: Animals; Male; Osteoclasts; Osteolysis; Prosthesis Failure; Rabbits; Teriparatide; Titanium; Zoledronic Acid | 2021 |
Irisin recouples osteogenesis and osteoclastogenesis to protect wear-particle-induced osteolysis by suppressing oxidative stress and RANKL production.
Topics: Animals; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Oxidative Stress; Titanium | 2021 |
Notoginsenoside R1 suppresses wear particle-induced osteolysis and RANKL mediated osteoclastogenesis in vivo and in vitro.
Topics: Animals; Arthroplasty, Replacement; Bone Resorption; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Ginsenosides; Humans; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoclasts; Osteolysis; Postoperative Complications; Prosthesis Failure; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium | 2017 |
Ten-Year Cross-Sectional Study of Mechanically Assisted Crevice Corrosion in 1352 Consecutive Patients With Metal-on-Polyethylene Total Hip Arthroplasty.
Topics: Aged; Arthroplasty, Replacement, Hip; C-Reactive Protein; Chromium; Chromium Alloys; Cobalt; Corrosion; Cross-Sectional Studies; Female; Femur Head; Hip Prosthesis; Humans; Maine; Male; Middle Aged; Osteolysis; Polyethylene; Postoperative Complications; Prevalence; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium | 2017 |
Midterm Outcomes of Revision Total Hip Arthroplasty With the Use of a Multihole Highly-Porous Titanium Shell.
Topics: Acetabulum; Adolescent; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Biocompatible Materials; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Joint Instability; Male; Middle Aged; Osteolysis; Porosity; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium; Treatment Outcome; Young Adult | 2017 |
Metallosis in a Dog as a Long-Term Complication Following Total Hip Arthroplasty.
Topics: Animals; Arthroplasty, Replacement, Hip; Chromium Alloys; Diagnosis, Differential; Dogs; Hip Prosthesis; Laser Capture Microdissection; Male; Metals; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Failure; Reoperation; Titanium | 2017 |
Kaempferide Prevents Titanium Particle Induced Osteolysis by Suppressing JNK Activation during Osteoclast Formation.
Topics: Animals; Anisomycin; Cell Differentiation; Cells, Cultured; Gene Expression Regulation; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Kaempferols; MAP Kinase Signaling System; Mice; Models, Molecular; Molecular Conformation; Osteoclasts; Osteogenesis; Osteolysis; Protective Agents; RANK Ligand; Structure-Activity Relationship; Titanium; X-Ray Microtomography | 2017 |
Comparison of an Uncemented Tapered Stem Design in Cobalt-Chrome vs Titanium at 15-Year Follow-Up.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Chromium; Chromium Alloys; Cobalt; Female; Follow-Up Studies; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Middle Aged; Osteolysis; Pain; Prosthesis Design; Radiography; Titanium; Young Adult | 2018 |
Strontium ranelate reduces the progression of titanium particle-induced osteolysis by increasing the ratio of osteoprotegerin to receptor activator of nuclear factor-κB ligand in vivo.
Topics: Administration, Oral; Alloys; Animals; Biomarkers; Bone Density Conservation Agents; Bone-Implant Interface; Dose-Response Relationship, Drug; Female; Gene Expression; Mice; Mice, Inbred C57BL; Osteolysis; Osteoprotegerin; Particulate Matter; Prostheses and Implants; Prosthesis Failure; RANK Ligand; Thiophenes; Tibia; Titanium | 2018 |
The degree of peri-implant osteolysis induced by PEEK, CoCrMo, and HXLPE wear particles: a study based on a porous Ti6Al4V implant in a rabbit model.
Topics: Alloys; Animals; Benzophenones; Biocompatible Materials; Female; Implants, Experimental; Ketones; Knee Joint; Models, Animal; Osteolysis; Particle Size; Polyethylene; Polyethylene Glycols; Polymers; Porosity; Rabbits; Titanium; Vitallium | 2018 |
Bulleyaconitine A prevents Ti particle-induced osteolysis via suppressing NF-κB signal pathway during osteoclastogenesis and osteoblastogenesis.
Topics: Aconitine; Animals; Bone Resorption; Cell Differentiation; Gene Expression Regulation; Male; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Signal Transduction; Skull; Titanium | 2018 |
Emodin attenuates titanium particle-induced osteolysis and RANKL-mediated osteoclastogenesis through the suppression of IKK phosphorylation.
Topics: Animals; Emodin; I-kappa B Kinase; Male; Mice; Mice, Inbred C57BL; Osteogenesis; Osteolysis; Phosphorylation; Prostheses and Implants; Protein Kinase Inhibitors; RANK Ligand; Titanium | 2018 |
Phelligridin D-loaded oral nanotube titanium implant enhances osseointegration and prevents osteolysis in rat mandible.
Topics: 3T3 Cells; Administration, Oral; Animals; Benzopyrans; Cell Differentiation; Cell Proliferation; Cell Survival; Drug Carriers; Drug Liberation; Male; Mandible; Mice; Nanotubes; Osseointegration; Osteoblasts; Osteogenesis; Osteolysis; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Titanium | 2018 |
Micrometer-Sized Titanium Particles Induce Aseptic Loosening in Rabbit Knee.
Topics: Animals; Arthroplasty, Replacement, Knee; Cell Differentiation; Femur; Knee Prosthesis; Osteoblasts; Osteoclasts; Osteolysis; Prosthesis Failure; Rabbits; Signal Transduction; Titanium | 2018 |
Protein phosphatase 2A as a new target for downregulating osteoclastogenesis and alleviating titanium particle-induced bone resorption.
Topics: Animals; Biopsy; Bone and Bones; Bone Resorption; Cell Survival; Homeostasis; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Materials Testing; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Phosphorylation; Prostheses and Implants; Protein Phosphatase 2; RANK Ligand; RNA, Small Interfering; Stress, Mechanical; Titanium; X-Ray Microtomography | 2018 |
Small Heterodimer Partner Negatively Regulates TLR4 Signaling Pathway of Titanium Particles-Induced Osteolysis in Mice.
Topics: Animals; Macrophages; Mice; Osteoclasts; Osteolysis; RAW 264.7 Cells; Signal Transduction; Titanium; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha | 2018 |
Hip resurfacing with a highly cross-linked polyethylene acetabular liner and a titanium nitride-coated femoral component.
Topics: Acetabulum; Adult; Aged; Arthroplasty, Replacement, Hip; Female; Femur; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Design; Radiography; Titanium; Tomography, X-Ray Computed; Young Adult | 2018 |
Gö6983 attenuates titanium particle-induced osteolysis and RANKL mediated osteoclastogenesis through the suppression of NFκB/JNK/p38 pathways.
Topics: Animals; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Down-Regulation; Durapatite; Humans; In Vitro Techniques; Indoles; Male; Maleimides; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; p38 Mitogen-Activated Protein Kinases; Prosthesis Failure; Protein Kinase Inhibitors; RANK Ligand; Skull; Titanium | 2018 |
Pulsed electromagnetic fields and platelet rich plasma alone and combined for the treatment of wear-mediated periprosthetic osteolysis: An in vivo study.
Topics: Alloys; Animals; Biomechanical Phenomena; Bone and Bones; Electromagnetic Fields; Hardness; Joint Prosthesis; Macrophages; Male; Osseointegration; Osteoclasts; Osteogenesis; Osteolysis; Platelet-Rich Plasma; Polyethylene; Polyethylenes; Rats; Rats, Inbred F344; Titanium; X-Ray Microtomography | 2018 |
Titanium particle‑mediated osteoclastogenesis may be attenuated via bidirectional ephrin‑B2/eph‑B4 signaling in vitro.
Topics: Animals; Antigens, Differentiation; Cell Line; Ephrin-B2; Female; Mice; Osteoclasts; Osteolysis; Signal Transduction; Titanium | 2018 |
Arctigenin inhibits RANKL-induced osteoclastogenesis and hydroxyapatite resorption in vitro and prevents titanium particle-induced bone loss in vivo.
Topics: Animals; Arthroplasty, Replacement; Bone Resorption; Cell Proliferation; Disease Models, Animal; Durapatite; Furans; Gene Expression Regulation, Developmental; Humans; Lignans; Mice; Osteoclasts; Osteogenesis; Osteolysis; Prostheses and Implants; RANK Ligand; Titanium; Transcription Factor RelA | 2019 |
Antiresorptive Agents are More Effective in Preventing Titanium Particle-Induced Calvarial Osteolysis in Ovariectomized Mice Than Anabolic Agents in Short-Term Administration.
Topics: Anabolic Agents; Animals; Bone Density Conservation Agents; Female; Mice; Osteolysis; Ovariectomy; Skull; Titanium | 2018 |
PEEK versus metal cages in posterior lumbar interbody fusion: a clinical and radiological comparative study.
Topics: Activities of Daily Living; Adult; Benzophenones; Biocompatible Materials; Female; Humans; Ketones; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Osteolysis; Pain Measurement; Polyethylene Glycols; Polymers; Retrospective Studies; Spinal Fusion; Tantalum; Titanium | 2019 |
Mechanism and Prevention of Titanium Particle-Induced Inflammation and Osteolysis.
Topics: Animals; Antibodies, Neutralizing; Cells, Cultured; Cytokines; Dental Implants; Disease Models, Animal; Female; Humans; Macrophages; Mice; Mice, Inbred C57BL; Osteogenesis; Osteolysis; Peri-Implantitis; Primary Cell Culture; Skull; Titanium; X-Ray Microtomography | 2018 |
Metallic wear debris collected from patients induces apoptosis in rat primary osteoblasts via reactive oxygen species‑mediated mitochondrial dysfunction and endoplasmic reticulum stress.
Topics: Animals; Apoptosis; Arthroplasty, Replacement, Hip; Endoplasmic Reticulum Stress; Hip Joint; Humans; Metals; Mitochondria; Osteoblasts; Osteolysis; Particle Size; Primary Cell Culture; Prostheses and Implants; Prosthesis Failure; Rats; Reactive Oxygen Species; Titanium | 2019 |
Vaccarin prevents titanium particle-induced osteolysis and inhibits RANKL-induced osteoclastogenesis by blocking NF-κB and MAPK signaling pathways.
Topics: Animals; Biomarkers; Bone Resorption; Cell Differentiation; Disease Models, Animal; Durapatite; Flavonoids; Gene Expression Regulation; Glycosides; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proto-Oncogene Proteins c-fos; RANK Ligand; RAW 264.7 Cells; Skull; Titanium | 2019 |
Osteocytes respond to particles of clinically-relevant conventional and cross-linked polyethylene and metal alloys by up-regulation of resorptive and inflammatory pathways.
Topics: Alloys; Antigens, Differentiation; Bone-Implant Interface; Humans; Osteocytes; Osteolysis; Polyethylenes; Titanium; Up-Regulation | 2019 |
Screw Track Osteolysis in the Cementless Total Knee Replacement Design.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Biocompatible Materials; Bone Cements; Bone Screws; Cementation; Equipment Failure Analysis; Female; Humans; Knee Prosthesis; Male; Middle Aged; Osteoarthritis, Knee; Osteolysis; Prosthesis Design; Prosthesis Failure; Tibia; Titanium | 2019 |
Anti-inflammatory drug-eluting implant model system to prevent wear particle-induced periprosthetic osteolysis.
Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Dexamethasone; Drug Liberation; Joint Prosthesis; Macrophages; Mice; Nanoparticles; Nitric Oxide; Osteolysis; Prosthesis Failure; RAW 264.7 Cells; Spectroscopy, Fourier Transform Infrared; Static Electricity; Temperature; Titanium; Tumor Necrosis Factor-alpha | 2019 |
Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways.
Topics: Animals; Cells, Cultured; Disaccharides; Flavonoids; Gene Expression; Glycosides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Osteogenesis; Osteolysis; Particle Size; Prosthesis Failure; RANK Ligand; Skull; Titanium; X-Ray Microtomography | 2019 |
MiR-377 inhibits wear particle-induced osteolysis via targeting RANKL.
Topics: Adult; Aged; Aged, 80 and over; Cell Differentiation; Cytokines; Down-Regulation; Female; Humans; Interleukin-6; Macrophages; Male; MicroRNAs; Middle Aged; Osteoclasts; Osteolysis; RANK Ligand; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha | 2019 |
NOD2 negatively regulated titanium particle-induced osteolysis in mice.
Topics: Aminoquinolines; Animals; Female; Humans; Inflammation Mediators; Macrophage Activation; Male; Mice; Middle Aged; NF-kappa B; Nod2 Signaling Adaptor Protein; Osteolysis; Prosthesis Failure; RAW 264.7 Cells; Signal Transduction; Sulfones; Titanium | 2019 |
Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway.
Topics: 3T3 Cells; Animals; beta Catenin; Ghrelin; Inflammation; Mice; Osteolysis; Particle Size; Particulate Matter; Protective Agents; Signal Transduction; Titanium | 2019 |
Pentamidine Inhibits Titanium Particle-Induced Osteolysis
Topics: Animals; Cell Differentiation; Cell Survival; Disease Models, Animal; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Pentamidine; Prostheses and Implants; RANK Ligand; Skull; Titanium; X-Ray Microtomography | 2019 |
Cepharanthine ameliorates titanium particle-induced osteolysis by inhibiting osteoclastogenesis and modulating OPG/RANKL ratio in a murine model.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Bone-Anchored Prosthesis; Bone-Implant Interface; Cathepsin D; Disease Models, Animal; Gene Expression Regulation; Male; Mice; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Prosthesis Failure; RANK Ligand; Skull; Tartrate-Resistant Acid Phosphatase; Titanium | 2019 |
Titanium particle-challenged osteoblasts promote osteoclastogenesis and osteolysis in a murine model of periprosthestic osteolysis.
Topics: Animals; Biocompatible Materials; Cell Differentiation; Dose-Response Relationship, Drug; Equipment Failure Analysis; Humans; Knee Prosthesis; Male; Materials Testing; Mice; Mice, Inbred BALB C; Osteoblasts; Osteoclasts; Osteolysis; Titanium | 2013 |
High survivorship with a titanium-encased alumina ceramic bearing for total hip arthroplasty.
Topics: Adult; Aluminum Oxide; Arthroplasty, Replacement, Hip; Female; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Noise; Osteolysis; Prosthesis Design; Prosthesis Failure; Stress, Mechanical; Time Factors; Titanium; Treatment Outcome; United States | 2014 |
Characterization of wear debris in total elbow arthroplasty.
Topics: Aged; Arthroplasty, Replacement, Elbow; Artifacts; Bone Cements; Chromium Alloys; Equipment Failure Analysis; Female; Humans; Joint Capsule; Joint Instability; Male; Microscopy, Electron, Scanning; Middle Aged; Osteolysis; Particle Size; Polyethylenes; Preoperative Care; Prosthesis Failure; Reoperation; Sampling Studies; Sensitivity and Specificity; Titanium | 2013 |
rna interference targeting p110β reduces tumor necrosis factor-alpha production in cellular response to wear particles in vitro and osteolysis in vivo.
Topics: Animals; Arthroplasty, Replacement; Cell Line; Ceramics; Class I Phosphatidylinositol 3-Kinases; Enzyme Activation; Inflammation; Joint Prosthesis; Lentivirus; Macrophages; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Osteoclasts; Osteolysis; Prosthesis Failure; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Messenger; RNA, Small Interfering; Titanium; Tumor Necrosis Factor-alpha | 2013 |
[Experimental study on small interfering RNA silencing expression of tumor necrosis factor alpha and inhibiting osteolysis].
Topics: Adenoviridae; Animals; Disease Models, Animal; Female; Gene Silencing; Genetic Therapy; HEK293 Cells; Humans; Joint Prosthesis; Mice; Mice, Inbred BALB C; Osteolysis; Prosthesis Failure; Random Allocation; RNA, Small Interfering; Titanium; Transfection; Tumor Necrosis Factor-alpha | 2013 |
Titanium and zirconia particle-induced pro-inflammatory gene expression in cultured macrophages and osteolysis, inflammatory hyperalgesia and edema in vivo.
Topics: Animals; Cells, Cultured; Cytokines; Edema; Gene Expression Regulation; Hyperalgesia; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteolysis; RNA, Messenger; Skull; Titanium; Toll-Like Receptors; Zirconium | 2014 |
Metal metaphyseal sleeves in revision total knee replacement.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Female; Follow-Up Studies; Humans; Knee Joint; Knee Prosthesis; Male; Middle Aged; Osseointegration; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Severity of Illness Index; Tibia; Titanium; Treatment Outcome | 2013 |
Particle-induced osteolysis is not accompanied by systemic remodeling but is reflected by systemic bone biomarkers.
Topics: Animals; Biomarkers; Bone and Bones; Bone Remodeling; Bone Resorption; Femur; Gene Expression Regulation; Humerus; Lumbar Vertebrae; Male; Osteolysis; Prostheses and Implants; Prosthesis Failure; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tibia; Titanium; X-Ray Microtomography | 2014 |
The effect of enoxacin on osteoclastogenesis and reduction of titanium particle-induced osteolysis via suppression of JNK signaling pathway.
Topics: Animals; Anti-Infective Agents; Cell Line; Enoxacin; Gene Expression Regulation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Prostheses and Implants; Titanium | 2014 |
Geraniin suppresses RANKL-induced osteoclastogenesis in vitro and ameliorates wear particle-induced osteolysis in mouse model.
Topics: Actins; Animals; Glucosides; Hydrolyzable Tannins; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proto-Oncogene Proteins c-fos; RANK Ligand; Skull; Titanium | 2015 |
Wear particles and ions from cemented and uncemented titanium-based hip prostheses-a histological and chemical analysis of retrieval material.
Topics: Adult; Aged; Aged, 80 and over; Alloys; Bone Cements; Device Removal; Female; Foreign-Body Reaction; Friction; Hip Joint; Hip Prosthesis; Histiocytes; Humans; Inflammation; Joint Capsule; Macrophages; Male; Middle Aged; Necrosis; Neutrophils; Osteolysis; Polyethylene; Prosthesis Failure; Titanium; Zirconium | 2015 |
Strontium ranelate inhibits titanium-particle-induced osteolysis by restraining inflammatory osteoclastogenesis in vivo.
Topics: Acid Phosphatase; Animals; Inflammation; Interleukin-1beta; Isoenzymes; Male; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; RANK Ligand; RNA, Messenger; Skull; Staining and Labeling; Tartrate-Resistant Acid Phosphatase; Thiophenes; Titanium; Tumor Necrosis Factor-alpha; X-Ray Microtomography | 2014 |
The prevention of titanium-particle-induced osteolysis by OA-14 through the suppression of the p38 signaling pathway and inhibition of osteoclastogenesis.
Topics: Acid Phosphatase; Actins; Animals; Benzamides; Bone Resorption; Cell Survival; Cells, Cultured; Indoles; Isoenzymes; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; RANK Ligand; Tartrate-Resistant Acid Phosphatase; Titanium | 2014 |
Porous titanium particles for acetabular reconstruction in total hip replacement show extensive bony armoring after 15 weeks. A loaded in vivo study in 10 goats.
Topics: Acetabulum; Animals; Arthroplasty, Replacement, Hip; Bone Transplantation; Calcium Phosphates; Cementation; Coated Materials, Biocompatible; Disease Models, Animal; Goats; Hip Prosthesis; Materials Testing; Osteolysis; Plastic Surgery Procedures; Polyethylene; Porosity; Prosthesis Failure; Titanium | 2014 |
Inhibitory effects of triptolide on titanium particle-induced osteolysis and receptor activator of nuclear factor-κB ligand-mediated osteoclast differentiation.
Topics: Acid Phosphatase; Animals; Blotting, Western; Cell Differentiation; Cell Survival; Diterpenes; Epoxy Compounds; Isoenzymes; Macrophages; Male; Mice; Mice, Inbred ICR; Osteoclasts; Osteolysis; Phenanthrenes; Receptor Activator of Nuclear Factor-kappa B; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Titanium | 2015 |
Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-қB activation and titanium particle-induced osteolysis in a mouse model.
Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line; Diterpenes; Epoxy Compounds; Mice; Osteoclasts; Osteolysis; Phenanthrenes; RANK Ligand; Titanium; Transcription Factor RelA | 2015 |
Myricetin prevents titanium particle-induced osteolysis in vivo and inhibits RANKL-induced osteoclastogenesis in vitro.
Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Flavonoids; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Particle Size; Random Allocation; RANK Ligand; Titanium | 2015 |
The inhibition of RANKL-induced osteoclastogenesis through the suppression of p38 signaling pathway by naringenin and attenuation of titanium-particle-induced osteolysis.
Topics: Actins; Animals; Anisomycin; Bone Resorption; Cell Death; Cell Differentiation; Extracellular Signal-Regulated MAP Kinases; Flavanones; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice, Inbred C57BL; Models, Biological; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; p38 Mitogen-Activated Protein Kinases; RANK Ligand; Titanium | 2014 |
Inhibitory effects of ursolic acid on osteoclastogenesis and titanium particle-induced osteolysis are mediated primarily via suppression of NF-κB signaling.
Topics: Animals; Male; MAP Kinase Kinase 4; Mice; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteolysis; RANK Ligand; Signal Transduction; Titanium; Triterpenes; Ursolic Acid | 2015 |
Protective effect of p38 MAPK inhibitor on wear debris-induced inflammatory osteolysis through downregulating RANK/RANKL in a mouse model.
Topics: Acid Phosphatase; Animals; Bone and Bones; Colonic Pouches; Disease Models, Animal; Down-Regulation; Female; Immunohistochemistry; Inflammation; Isoenzymes; Mice, Inbred BALB C; Osteolysis; p38 Mitogen-Activated Protein Kinases; Prostheses and Implants; Protective Agents; Protein Kinase Inhibitors; RANK Ligand; Real-Time Polymerase Chain Reaction; Receptor Activator of Nuclear Factor-kappa B; Tartrate-Resistant Acid Phosphatase; Titanium | 2015 |
Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway.
Topics: Animals; Apoptosis; Arthroplasty, Replacement, Hip; Chemokine CCL2; Cytokine TWEAK; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Macrophages; MAP Kinase Signaling System; Mice; Osteolysis; p38 Mitogen-Activated Protein Kinases; Titanium; Tumor Necrosis Factors | 2015 |
Icariin protects against titanium particle-induced osteolysis and inflammatory response in a mouse calvarial model.
Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Epimedium; Flavonoids; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Osteolysis; Skull; Titanium; Tumor Necrosis Factor-alpha | 2015 |
Primary ceramic-on-ceramic total hip arthroplasty using a 32-mm ceramic head with a titanium-alloy sleeve.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Disease-Free Survival; Female; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Male; Metal Ceramic Alloys; Middle Aged; Noise; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Republic of Korea; Retrospective Studies; Risk Factors; Surveys and Questionnaires; Time Factors; Titanium; Treatment Outcome; Young Adult | 2015 |
Polycan suppresses osteoclast differentiation and titanium particle-induced osteolysis in mice.
Topics: Animals; Ascomycota; Cell Differentiation; Cytokines; Fungal Polysaccharides; Mice; Mice, Inbred ICR; Osteoclasts; Osteolysis; Titanium | 2016 |
Lycorine suppresses RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced osteoporosis and titanium particle-induced osteolysis in vivo.
Topics: Amaryllidaceae Alkaloids; Animals; Bone Density Conservation Agents; Bone Marrow; Cell Differentiation; Cell Survival; Disease Models, Animal; Female; Gene Expression Regulation; Macrophages; Male; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Mice; Mice, Inbred C57BL; Mice, Transgenic; Osteoclasts; Osteogenesis; Osteolysis; Osteoporosis; Ovariectomy; Phenanthridines; Primary Cell Culture; RANK Ligand; Signal Transduction; Titanium | 2015 |
Pharmaceutical inhibition of glycogen synthetase kinase 3 beta suppresses wear debris-induced osteolysis.
Topics: Animals; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium Chloride; Mice; Mice, Inbred C57BL; Osteolysis; Prostheses and Implants; Protein Kinase Inhibitors; Skull; Titanium | 2015 |
Diagnosis and Management of Adverse Local Tissue Reactions Secondary to Corrosion at the Head-Neck Junction in Patients With Metal on Polyethylene Bearings.
Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Blood Sedimentation; Body Mass Index; Ceramics; Chromium; Cobalt; Corrosion; Disease Management; Female; Foreign-Body Reaction; Hip Prosthesis; Humans; Male; Metals; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium | 2016 |
Inhibition of RANKL-induced osteoclastogenesis through the suppression of the ERK signaling pathway by astragaloside IV and attenuation of titanium-particle-induced osteolysis.
Topics: Animals; Cell Line; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Ligands; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Saponins; Titanium; Triterpenes | 2015 |
ER Stress Mediates TiAl6V4 Particle-Induced Peri-Implant Osteolysis by Promoting RANKL Expression in Fibroblasts.
Topics: Alloys; Animals; Biomarkers; Bone-Implant Interface; Cells, Cultured; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Fibroblasts; Gene Expression Regulation; Humans; Male; Mice; Osteolysis; RANK Ligand; Titanium | 2015 |
Expression of XBP1s in fibroblasts is critical for TiAl
Topics: Aged; Alloys; Animals; Arthroplasty, Replacement, Hip; Female; Fibroblasts; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Osteoclasts; Osteolysis; Prosthesis Failure; RANK Ligand; RNA, Small Interfering; Synovial Membrane; Titanium; X-Box Binding Protein 1; X-Ray Microtomography | 2017 |
Nanoscale surface modification by anodic oxidation increased bone ingrowth and reduced fibrous tissue in the porous coating of titanium-alloy femoral hip arthroplasty implants.
Topics: Alloys; Animals; Arthroplasty, Replacement, Hip; Dogs; Hip Prosthesis; Male; Osteolysis; Oxidation-Reduction; Surface Properties; Titanium | 2017 |
Inhibition of titanium-particle-induced inflammatory osteolysis after local administration of dopamine and suppression of osteoclastogenesis via D2-like receptor signaling pathway.
Topics: Animals; Cells, Cultured; Dopamine; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice, Inbred C57BL; Osteoclasts; Osteolysis; RANK Ligand; Receptors, Dopamine D2; Signal Transduction; Skull; Titanium; Tumor Necrosis Factor-alpha; X-Ray Microtomography | 2016 |
Dihydroartemisinin prevents breast cancer-induced osteolysis via inhibiting both breast caner cells and osteoclasts.
Topics: Actins; Animals; Artemisinins; Bone Density; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; Titanium; Xenograft Model Antitumor Assays | 2016 |
Biomechanical Analysis of Implanted Clavicle Hook Plates With Different Implant Depths and Materials in the Acromioclavicular Joint: A Finite Element Analysis Study.
Topics: Acromioclavicular Joint; Alloys; Biomechanical Phenomena; Bone Plates; Clavicle; Computer Simulation; Finite Element Analysis; Fracture Fixation, Internal; Humans; Joint Dislocations; Osteolysis; Periprosthetic Fractures; Postoperative Complications; Stainless Steel; Titanium; Treatment Outcome | 2016 |
Progranulin suppresses titanium particle induced inflammatory osteolysis by targeting TNFα signaling.
Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Line; Gene Expression; Granulins; I-kappa B Kinase; Inflammation; Intercellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Particle Size; Phosphorylation; Progranulins; RANK Ligand; Signal Transduction; Skull; Titanium; Transcription Factor RelA; Tumor Necrosis Factor-alpha | 2016 |
Resveratrol Protects against Titanium Particle-Induced Aseptic Loosening Through Reduction of Oxidative Stress and Inactivation of NF-κB.
Topics: Animals; Antioxidants; Catalase; Cell Line; Female; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Osteolysis; Oxidative Stress; Prostheses and Implants; RAW 264.7 Cells; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Titanium; Tumor Necrosis Factor-alpha | 2016 |
Particle-Induced Osteolysis Is Mediated by TIRAP/Mal in Vitro and in Vivo: Dependence on Adherent Pathogen-Associated Molecular Patterns.
Topics: Animals; Biomarkers; Cytokines; Female; Joint Prosthesis; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteolysis; Pathogen-Associated Molecular Pattern Molecules; Prosthesis Failure; Random Allocation; Receptors, Interleukin-1; Titanium | 2016 |
Adenovirus-mediated siRNA targeting CXCR2 attenuates titanium particle-induced osteolysis by suppressing osteoclast formation.
Topics: Adenoviridae; Animals; Bone Marrow Cells; Female; Macrophages; Mice; Mice, Inbred BALB C; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; RANK Ligand; RAW 264.7 Cells; Receptors, Interleukin-8B; RNA, Small Interfering; Signal Transduction; Skull; Titanium; Up-Regulation | 2016 |
Autophagy mediated TiAl₆V₄ particle-induced peri-implant osteolysis by promoting expression of TNF-α.
Topics: Adenine; Aged; Aged, 80 and over; Alloys; Animals; Autophagy; Disease Models, Animal; Female; Humans; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Middle Aged; Osteolysis; p38 Mitogen-Activated Protein Kinases; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha; Up-Regulation; X-Ray Microtomography | 2016 |
Highly Cross-linked Polyethylene Provides Decreased Osteolysis and Reoperation at Minimum 10-Year Follow-Up.
Topics: Acetabulum; Adult; Aged; Arthroplasty, Replacement, Hip; Bone Screws; Female; Follow-Up Studies; Hip Prosthesis; Humans; Incidence; Male; Middle Aged; North Carolina; Osteolysis; Polyethylene; Prosthesis Failure; Reoperation; Titanium | 2016 |
Icariin attenuates titanium-particle inhibition of bone formation by activating the Wnt/β-catenin signaling pathway in vivo and in vitro.
Topics: Administration, Topical; Animals; beta Catenin; Bone-Implant Interface; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Drugs, Chinese Herbal; Female; Flavonoids; Gene Expression; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Primary Cell Culture; Pyrimidinones; Signal Transduction; Skull; Titanium | 2016 |
Backside Wear Analysis of Retrieved Acetabular Liners with a Press-Fit Locking Mechanism in Comparison to Wear Simulation In Vitro.
Topics: Acetabulum; Alloys; Internal Fixators; Materials Testing; Motion; Osteolysis; Polyethylenes; Prosthesis Failure; Stress, Mechanical; Surface Properties; Titanium | 2016 |
Scutellarin inhibits RANKL-mediated osteoclastogenesis and titanium particle-induced osteolysis via suppression of NF-κB and MAPK signaling pathway.
Topics: Animals; Anti-Inflammatory Agents; Apigenin; Bone Resorption; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Glucuronates; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Microspheres; NF-kappa B; Osteoclasts; Osteolysis; Prosthesis Failure; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium | 2016 |
Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo.
Topics: Animals; Ceramics; Disease Models, Animal; Gene Knockdown Techniques; Genetic Vectors; Humans; Inflammation; Joint Prosthesis; Lentivirus; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteolysis; Particle Size; Prosthesis Failure; RAW 264.7 Cells; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; RNAi Therapeutics; Skull; Titanium; Tumor Necrosis Factor-alpha | 2016 |
Platelet-derived growth factor-BB attenuates titanium-particle-induced osteolysis in vivo.
Topics: Animals; Becaplermin; Bone-Implant Interface; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred C57BL; Osteolysis; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-sis; Titanium; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2016 |
Theaflavin-3,3'-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway.
Topics: Animals; Biflavonoids; Bone Resorption; Catechin; Gene Expression Regulation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; RAW 264.7 Cells; Skull; Titanium | 2017 |
SIRT1 protects osteoblasts against particle-induced inflammatory responses and apoptosis in aseptic prosthesis loosening.
Topics: Alloys; Animals; Apoptosis; Cell Line; Cytoprotection; Disease Models, Animal; Down-Regulation; Fluorescent Antibody Technique; Inflammation; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteolysis; Prosthesis Failure; Signal Transduction; Sirtuin 1; Titanium; Tumor Suppressor Protein p53 | 2017 |
Incidence of Ceramic Liner Malseating After Ceramic-on-Ceramic Total Hip Arthroplasty Associated With Osteolysis: A 5- to 15-Year Follow-Up Study.
Topics: Acetabulum; Adult; Aged; Alloys; Arthroplasty, Replacement, Hip; Ceramics; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Risk Factors; Titanium; Treatment Outcome | 2017 |
Scaling of titanium implants entrains inflammation-induced osteolysis.
Topics: Animals; Cells, Cultured; Dental Implants; Dental Scaling; Female; Mice, Inbred C57BL; Osteogenesis; Osteolysis; Peri-Implantitis; Titanium | 2017 |
Suppression of osteogenic activity by regulation of WNT and BMP signaling during titanium particle induced osteolysis.
Topics: Animals; Bone Morphogenetic Proteins; Cell Line; Male; Mice; Mice, Inbred ICR; Osteoclasts; Osteogenesis; Osteolysis; Titanium; Wnt Signaling Pathway | 2017 |
Melatonin attenuates titanium particle-induced osteolysis via activation of Wnt/β-catenin signaling pathway.
Topics: Animals; beta Catenin; Bone Regeneration; Cell Differentiation; Disease Models, Animal; Intercellular Signaling Peptides and Proteins; Male; Melatonin; Mesenchymal Stem Cells; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; RANK Ligand; Skull; Titanium; Wnt Signaling Pathway | 2017 |
Rifampin suppresses osteoclastogenesis and titanium particle-induced osteolysis via modulating RANKL signaling pathways.
Topics: Animals; Cell Differentiation; Dose-Response Relationship, Drug; Gene Expression; Mice; NF-kappa B; Osteogenesis; Osteolysis; p38 Mitogen-Activated Protein Kinases; RANK Ligand; Rifampin; Signal Transduction; Titanium; X-Ray Microtomography | 2017 |
11R-VIVIT Peptide Inhibits Calvaria Osteolysis Induced by Experimental Design.
Topics: Animals; Drug Administration Schedule; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Oligopeptides; Osteoclasts; Osteogenesis; Osteolysis; Prostheses and Implants; Prosthesis Failure; Research Design; Skull; Titanium | 2017 |
Osteolysis in third-generation alumina ceramic-on-ceramic hip bearings with severe impingement and titanium metallosis.
Topics: Adult; Aluminum Oxide; Arthroplasty, Replacement, Hip; Ceramics; Female; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Range of Motion, Articular; Titanium | 2008 |
The results of the titanium-coated RM acetabular component at 20 years: a long-term follow-up of an uncemented primary total hip replacement.
Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Equipment Failure Analysis; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prospective Studies; Prosthesis Design; Prosthesis-Related Infections; Range of Motion, Articular; Retreatment; Titanium; Treatment Outcome | 2008 |
Primary total hip arthroplasty in severe developmental dysplasia of the hip. Ten-year results using a cementless modular stem.
Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Bone Diseases, Developmental; Bone Transplantation; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Longitudinal Studies; Male; Middle Aged; Osteolysis; Outcome Assessment, Health Care; Radiography; Risk Factors; Titanium | 2009 |
Wear is reduced in THA performed with highly cross-linked polyethylene.
Topics: Adult; Arthroplasty, Replacement, Hip; Chromium Alloys; Cross-Linking Reagents; Female; Follow-Up Studies; Hip Prosthesis; Humans; Incidence; Male; Middle Aged; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Failure; Titanium | 2009 |
Skull bone flap fixation--comparative experimental study to assess the reliability of a new grip-like titanium device (Skull Grip) versus traditional sutures: technical note.
Topics: Cadaver; Craniotomy; Humans; Neurosurgical Procedures; Osteolysis; Plastic Surgery Procedures; Postoperative Complications; Prostheses and Implants; Pseudarthrosis; Reproducibility of Results; Skull; Stress, Mechanical; Surgical Flaps; Titanium; Treatment Outcome; Weight-Bearing; Wound Healing | 2009 |
Low dose metal particles can induce monocyte/macrophage survival.
Topics: Alloys; Animals; Cell Survival; Cells, Cultured; Chromium Alloys; Culture Media, Conditioned; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Metals; Mice; Monocytes; Osteolysis; Titanium | 2009 |
Reduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiation.
Topics: Animals; CD11b Antigen; Cell Differentiation; Inflammation; Interleukin-6; Macrophage Colony-Stimulating Factor; Mice; Osteoclasts; Osteogenesis; Osteolysis; Spleen; Stem Cells; Titanium; Tumor Necrosis Factor-alpha | 2009 |
Severe periprosthetic osteolytic lesions after the Ankle Evolutive System total ankle replacement.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ankle Joint; Arthroplasty, Replacement; Durapatite; Female; Humans; Image Interpretation, Computer-Assisted; Joint Prosthesis; Male; Middle Aged; Osteolysis; Radiography; Titanium; Young Adult | 2009 |
Cemented total hip replacement cable debris and acetabular construct durability.
Topics: Acetabulum; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cementation; Chromium Alloys; Follow-Up Studies; Hip Prosthesis; Humans; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Stainless Steel; Survival Analysis; Titanium | 2009 |
Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles.
Topics: Cell Survival; Cells, Cultured; Cytokines; Humans; Inflammation Mediators; Macrophages; Microscopy, Electron, Scanning; Nanoparticles; Osteolysis; Particle Size; Phagocytosis; Titanium | 2010 |
Backside volumetric change in the polyethylene of uncemented acetabular components.
Topics: Acetabulum; Aged; Arthroplasty, Replacement, Hip; Female; Finite Element Analysis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium | 2009 |
The effect of osteoprotegerin gene modification on wear debris-induced osteolysis in a murine model of knee prosthesis failure.
Topics: Animals; Dependovirus; Interleukin-1; Knee Prosthesis; Mice; Mice, Inbred BALB C; Osteolysis; Osteoprotegerin; Prosthesis Design; Prosthesis Failure; RANK Ligand; RNA, Messenger; Time Factors; Tissue Distribution; Titanium; Transgenes; Tumor Necrosis Factor-alpha | 2009 |
High survival of uncemented proximally porous-coated titanium alloy femoral stems in osteoporotic bone.
Topics: Aged; Alloys; Arthroplasty, Replacement, Hip; Coated Materials, Biocompatible; Female; Femur; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Osteolysis; Osteoporosis; Pain; Pain Measurement; Porosity; Prosthesis Design; Prosthesis Failure; Radiography; Recovery of Function; Retrospective Studies; Severity of Illness Index; Stress, Mechanical; Surface Properties; Time Factors; Titanium; Treatment Outcome | 2010 |
Promotion of bone formation by naringin in a titanium particle-induced diabetic murine calvarial osteolysis model.
Topics: Animals; Bone Substitutes; Collagen Type I; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drugs, Chinese Herbal; Flavanones; Fracture Healing; Male; Mice; Mice, Inbred C57BL; Osteocalcin; Osteogenesis; Osteolysis; Peptides; Phytotherapy; Plant Extracts; Polypodiaceae; Skull; Titanium; Tomography, X-Ray Computed | 2010 |
Protection against titanium particle induced osteolysis by cannabinoid receptor 2 selective antagonist.
Topics: Animals; Female; Humans; Indoles; Mice; Mice, Inbred BALB C; Osteoclasts; Osteolysis; Particle Size; Prosthesis Failure; RANK Ligand; Receptor, Cannabinoid, CB2; Skull; Titanium | 2010 |
The effects of local and systemic alendronate delivery on wear debris-induced osteolysis in vivo.
Topics: Absorptiometry, Photon; Alendronate; Animals; Biomechanical Phenomena; Biopsy; Bone Cements; Bone Density; Bone Density Conservation Agents; Dose-Response Relationship, Drug; Injections, Subcutaneous; Knee Joint; Male; Osteolysis; Polymethyl Methacrylate; Rabbits; Titanium | 2010 |
Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages.
Topics: Animals; Cells, Cultured; Chemokine CCL3; Cytokines; Disease Models, Animal; Female; I-kappa B Proteins; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Osteolysis; Osteopontin; Phagocytosis; Skull; Titanium; Tumor Necrosis Factor-alpha | 2010 |
Individual susceptibility to periprosthetic osteolysis is associated with altered patterns of innate immune gene expression in response to pro-inflammatory stimuli.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Case-Control Studies; Cytokines; Female; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Failure; Reoperation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Titanium | 2010 |
Treating lumbar spinal canal stenosis by injecting insoluble particles.
Topics: Humans; Lumbar Vertebrae; Osteolysis; Particulate Matter; Polyethylene; Spinal Stenosis; Titanium | 2010 |
[Medium-term results of anatomic straight-shaft IMAGE implantation in primary hip joint endoprosthetics--a prospective study].
Topics: Adult; Aged; Aged, 80 and over; Alloys; Biomechanical Phenomena; Bone Remodeling; Equipment Failure Analysis; Female; Femur; Hip Prosthesis; Humans; Hyperostosis; Image Processing, Computer-Assisted; Male; Middle Aged; Osseointegration; Osteolysis; Postoperative Complications; Prospective Studies; Prosthesis Design; Titanium; Tomography, X-Ray Computed; Weight-Bearing | 2010 |
Efficacy of periprosthetic erythromycin delivery for wear debris-induced inflammation and osteolysis.
Topics: Animals; Anti-Bacterial Agents; Coated Materials, Biocompatible; Erythromycin; Humans; Implants, Experimental; Inflammation; Osteolysis; Polyethylenes; Prosthesis Failure; Rats; Rats, Sprague-Dawley; Tibia; Titanium | 2010 |
Inhibition of titanium particle-induced inflammatory osteolysis through inactivation of cannabinoid receptor 2 by AM630.
Topics: Animals; Cell Survival; Cells, Cultured; Cytokines; Gene Expression Regulation; Indoles; Inflammation; Inflammation Mediators; Mice; Microscopy, Electron, Scanning; Osteoclasts; Osteogenesis; Osteolysis; Receptor, Cannabinoid, CB2; Titanium | 2010 |
Periprosthetic osteolysis: characterizing the innate immune response to titanium wear-particles.
Topics: Animals; Arthroplasty, Replacement, Hip; Carrier Proteins; Cells, Cultured; Humans; Immunity, Innate; Interleukin-1; Macrophages; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; Titanium | 2010 |
Midterm results of 506 solid trispiked reflection cementless acetabular components for primary total hip arthroplasty.
Topics: Acetabulum; Adult; Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cohort Studies; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Incidence; Kaplan-Meier Estimate; Longitudinal Studies; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Prospective Studies; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Sex Factors; Titanium; Treatment Outcome | 2011 |
High rate of osteolytic lesions in medium-term followup after the AES total ankle replacement.
Topics: Adult; Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Ankle; Coated Materials, Biocompatible; Durapatite; Female; Follow-Up Studies; Humans; Joint Prosthesis; Male; Middle Aged; Osteoarthritis; Osteolysis; Prosthesis Design; Radiography; Reoperation; Retrospective Studies; Titanium; Young Adult | 2011 |
Polymethylmethacrylate and titanium alloy particles activate peripheral monocytes during periprosthetic inflammation and osteolysis.
Topics: Alloys; Animals; Arthroplasty, Replacement; Bone Transplantation; Humans; Inflammation; Leukocytes, Mononuclear; Mice; Mice, SCID; Osteolysis; Polymethyl Methacrylate; Titanium; Transplantation, Heterologous; X-Ray Microtomography | 2011 |
Vascular endothelial growth factor gene silencing suppresses wear debris-induced inflammation.
Topics: Alloys; Animals; Bone Resorption; Disease Models, Animal; Female; Gene Silencing; Genetic Vectors; Inflammation; Lentivirus; Mice; Mice, Inbred BALB C; MicroRNAs; Osteolysis; Prosthesis Failure; Titanium; Transfection; Vascular Endothelial Growth Factor A | 2011 |
Silent soft tissue pathology is common with a modern metal-on-metal hip arthroplasty.
Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Chromium; Cobalt; Edema; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium; Treatment Outcome | 2011 |
PI3Kγ deletion reduces variability in the in vivo osteolytic response induced by orthopaedic wear particles.
Topics: Animals; Class Ib Phosphatidylinositol 3-Kinase; Female; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Osteitis; Osteolysis; Parietal Bone; Polyethylene; Prosthesis Failure; Signal Transduction; Titanium | 2011 |
Posterior condyle surface damage on retrieved femoral knee components.
Topics: Arthroplasty, Replacement, Knee; Chromium Alloys; Female; Femur; Humans; Knee Joint; Knee Prosthesis; Male; Microscopy, Electron, Scanning; Niobium; Osteoarthritis, Knee; Osteolysis; Prosthesis Design; Prosthesis Failure; Range of Motion, Articular; Reoperation; Retrospective Studies; Surface Properties; Titanium; Zirconium | 2011 |
Protective effects of COX-2 inhibitor on titanium-particle-induced inflammatory osteolysis via the down-regulation of RANK/RANKL.
Topics: Acid Phosphatase; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Immunohistochemistry; Interleukin-1beta; Isoenzymes; Isoxazoles; Membranes; Mice; Mice, Inbred BALB C; Osteoclasts; Osteogenesis; Osteolysis; Particulate Matter; Protective Agents; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Tartrate-Resistant Acid Phosphatase; Titanium; Tumor Necrosis Factor-alpha | 2011 |
Inhibitory effect of (-)-epigallocatechin gallate on titanium particle-induced TNF-α release and in vivo osteolysis.
Topics: Animals; Catechin; Cell Line; Implants, Experimental; Macrophages; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 8; NF-kappa B; Osteolysis; Particulate Matter; Prosthesis Failure; Signal Transduction; Skull; Titanium; Transcription Factor AP-1; Tumor Necrosis Factor-alpha | 2011 |
Second-generation modular acetabular components provide fixation at 10 to 16 years.
Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Bone Cements; Bone Screws; Female; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Male; Middle Aged; North Carolina; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Range of Motion, Articular; Recovery of Function; Reoperation; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Titanium; Treatment Outcome; Young Adult | 2012 |
Low-dose captopril inhibits wear debris-induced inflammatory osteolysis.
Topics: Animals; Base Sequence; Captopril; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Female; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Osteolysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Titanium | 2011 |
The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particles.
Topics: Apoptosis; Arthroplasty, Replacement, Hip; Biocompatible Materials; Bone Cements; Bone Substitutes; Collagen Type I; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-6; Interleukin-8; Materials Testing; Matrix Metalloproteinase 1; Osteoblasts; Osteolysis; Particle Size; Polymethyl Methacrylate; Primary Cell Culture; Prostheses and Implants; Stainless Steel; Titanium; Vascular Endothelial Growth Factor A; Zirconium | 2011 |
Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells.
Topics: Actins; Adhesiveness; Animals; Benzimidazoles; Bone and Bones; CCAAT-Enhancer-Binding Protein-beta; Cyclooxygenase 2; Cytochalasin D; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Immunity, Innate; Inflammation; Interleukin-6; MAP Kinase Signaling System; Mice; Models, Biological; Osteogenesis; Osteolysis; Phagocytosis; Protein Kinase Inhibitors; Signal Transduction; Skull; Stem Cells; Time Factors; Titanium | 2011 |
Macrophage response to high number of titanium particles is cytotoxic and COX-2 mediated and it is not affected by the particle's endotoxin content or the cleaning treatment.
Topics: Animals; Bone and Bones; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Endotoxins; Macrophage Activation; Macrophages; Materials Testing; Mice; Osteolysis; Particle Size; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha | 2011 |
Therapeutic potential of the proteasome inhibitor Bortezomib on titanium particle-induced inflammation in a murine model.
Topics: Animals; Boronic Acids; Bortezomib; Female; I-kappa B Kinase; Inflammation; Inflammation Mediators; Joint Prosthesis; Mice; Mice, Inbred BALB C; NF-kappa B; Osteolysis; Prosthesis Failure; Proteasome Inhibitors; Pyrazines; Random Allocation; Titanium; Tumor Necrosis Factor-alpha | 2012 |
Biological responses of human mesenchymal stem cells to titanium wear debris particles.
Topics: Adherens Junctions; Apoptosis; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Cytoskeleton; Dose-Response Relationship, Drug; Endocytosis; Gene Expression; Gene Expression Profiling; Humans; Interleukin-6; Interleukin-8; Mesenchymal Stem Cells; Osteogenesis; Osteolysis; Particulate Matter; Titanium | 2012 |
Involvement of extracellular Hsp72 in wear particle-mediated osteolysis.
Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cells, Cultured; Female; Hip Prosthesis; HSP72 Heat-Shock Proteins; Humans; Inflammation; Interleukin-1beta; Macrophage Activation; Male; Middle Aged; Osteoclasts; Osteolysis; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha | 2012 |
Protection against titanium particle-induced inflammatory osteolysis by the proteasome inhibitor bortezomib in vivo.
Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Arthroplasty, Replacement; Boronic Acids; Bortezomib; Female; Inflammation; Mice; Mice, Inbred BALB C; Osteolysis; Osteoprotegerin; Prosthesis Failure; Proteasome Inhibitors; Pyrazines; Random Allocation; RANK Ligand; Titanium; TNF Receptor-Associated Factor 6; Vascular Endothelial Growth Factors | 2012 |
A concise minimum eight year follow-up of proximally porous-coated tapered titanium femoral stem in primary total hip arthroplasty.
Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Incidence; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Patient Satisfaction; Porosity; Prospective Studies; Radiography; Retrospective Studies; Titanium; Treatment Outcome | 2012 |
Prevention of wear particle-induced osteolysis by a novel V-ATPase inhibitor saliphenylhalamide through inhibition of osteoclast bone resorption.
Topics: Amides; Animals; Anti-Bacterial Agents; Arthroplasty, Replacement; Cell Polarity; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Mice; NF-kappa B; Osteoclasts; Osteolysis; RANK Ligand; Salicylates; Signal Transduction; Skull; Titanium; Vacuolar Proton-Translocating ATPases | 2012 |
Inhibitory effects of luteolin on titanium particle-induced osteolysis in a mouse model.
Topics: Animals; Base Sequence; Cell Differentiation; Culture Media, Conditioned; Disease Models, Animal; DNA Primers; Luteolin; Male; Mice; Mice, Inbred ICR; Osteoclasts; Osteolysis; Prostheses and Implants; Reverse Transcriptase Polymerase Chain Reaction; Titanium | 2012 |
In vitro comparison of the biological activity of alumina ceramic and titanium particles associated with aseptic loosening.
Topics: Aluminum Oxide; Animals; Biocompatible Materials; Cell Line; Cytokines; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; In Vitro Techniques; Inflammation; Joint Prosthesis; Macrophages; Mice; Osteolysis; Particle Size; Polymerase Chain Reaction; Prosthesis Design; RANK Ligand; Titanium; Tumor Necrosis Factor-alpha | 2012 |
Inhibition of p38 mitogen-activated protein kinase down-regulates the inflammatory osteolysis response to titanium particles in a murine osteolysis model.
Topics: Acid Phosphatase; Animals; Bone and Bones; Down-Regulation; Enzyme Inhibitors; Female; Imidazoles; Inflammation; Isoenzymes; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Osteoclasts; Osteolysis; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; Tartrate-Resistant Acid Phosphatase; Titanium; Tumor Necrosis Factor-alpha | 2012 |
Second-generation uncemented stems: excellent 5-13-year results.
Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Bone Cements; Female; Femoral Fractures; Femur; Hip; Humans; Hypertrophy; Male; Middle Aged; Osteolysis; Pain; Postoperative Complications; Prospective Studies; Prosthesis Design; Prosthesis Failure; Radiography; Titanium; Treatment Outcome; Young Adult | 2009 |
MMP-9 inhibition suppresses wear debris-induced inflammatory osteolysis through downregulation of RANK/RANKL in a murine osteolysis model.
Topics: Animals; Arthroplasty; Cell Differentiation; Drug Evaluation, Preclinical; Female; Gene Expression; Gene Expression Regulation, Enzymologic; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Osteitis; Osteoclasts; Osteolysis; Particulate Matter; Prosthesis Failure; Protein Synthesis Inhibitors; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Tetracycline; Titanium; Tumor Necrosis Factor-alpha | 2012 |
Influence of statins locally applied from orthopedic implants on osseous integration.
Topics: Animals; Biomechanical Phenomena; Coated Materials, Biocompatible; Dose-Response Relationship, Drug; Female; Femur; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Osseointegration; Osteolysis; Polyesters; Prosthesis Design; Prosthesis Implantation; Radiography; Rats; Rats, Sprague-Dawley; Simvastatin; Time Factors; Titanium | 2012 |
Ten- to 15-year clinical and radiographic results for a compression molded monoblock elliptical acetabular component.
Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium; Treatment Outcome | 2012 |
Viral interleukin-10 gene inhibition of inflammation, osteoclastogenesis, and bone resorption in response to titanium particles.
Topics: Adenoviridae; Animals; Cells, Cultured; Fibroblasts; Genetic Therapy; Genetic Vectors; Inflammation; Interleukin-1; Interleukin-10; Interleukin-6; Macrophages; Osteoclasts; Osteolysis; Skull; Spleen; Synovial Membrane; Titanium; Transduction, Genetic; Transgenes; Tumor Necrosis Factor-alpha; Viral Proteins | 2002 |
Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles.
Topics: Animals; Apoptosis; Biocompatible Materials; Caspase 3; Caspases; Cell Culture Techniques; Gene Expression Profiling; Humans; Joint Prosthesis; Osteoblasts; Osteolysis; Particle Size; Prosthesis Failure; Rats; Titanium | 2002 |
The influence of biomaterial on patterns of failure after cemented total hip replacement.
Topics: Adult; Aged; Aged, 80 and over; Biocompatible Materials; Cementation; Chromium; Cobalt; Equipment Failure Analysis; Female; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Statistics, Nonparametric; Titanium | 2002 |
The effect of titanium particulate on development and maintenance of a posterolateral spinal arthrodesis: an in vivo rabbit model.
Topics: Acid Phosphatase; Animals; Apoptosis; Bone Transplantation; Cell Count; Cytokines; Ilium; Immunohistochemistry; Implants, Experimental; Inflammation; Lumbar Vertebrae; Macrophages; Models, Animal; Osteoclasts; Osteolysis; Particle Size; Rabbits; Radiography; Spinal Fusion; Titanium; Treatment Outcome; Tumor Necrosis Factor-alpha | 2002 |
Case report: metaphyseal osteolysis around a titanium reconstruction nail.
Topics: Bone Nails; Bone Screws; Female; Femoral Fractures; Fracture Fixation, Intramedullary; Humans; Middle Aged; Osteolysis; Postoperative Complications; Radiography; Titanium | 2003 |
Premature failure of a hip hemiarthroplasty secondary to osteolysis and aseptic loosening.
Topics: Aged; Arthroplasty; Arthroplasty, Replacement, Hip; Foreign-Body Reaction; Hip Prosthesis; Humans; Male; Osteolysis; Polyethylenes; Prosthesis Failure; Reoperation; Surface Properties; Titanium | 2003 |
Long-term radiographic changes in cemented total hip arthroplasty with six designs of femoral components.
Topics: Aged; Alloys; Arthroplasty, Replacement, Hip; Bone Cements; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Stainless Steel; Time Factors; Titanium | 2003 |
Biological reaction to alumina, zirconia, titanium and polyethylene particles implanted onto murine calvaria.
Topics: Aluminum; Animals; Arthroplasty, Replacement, Hip; Biocompatible Materials; Bone Substitutes; Ceramics; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Hip Prosthesis; Interleukin-1; Interleukin-6; Mice; Microscopy, Electron; Organ Culture Techniques; Osteolysis; Polyethylene; Prostheses and Implants; Time Factors; Titanium; Tumor Necrosis Factor-alpha; Zirconium | 2003 |
A comparison of cemented and cementless titanium femoral components used for primary total hip arthroplasty: a radiographic and survivorship study. By Emerson RH Jr, et al.
Topics: Acetabulum; Arthroplasty, Replacement, Hip; Cementation; Equipment Failure Analysis; Femur; Hip Prosthesis; Humans; Osteolysis; Prosthesis Design; Radiography; Reoperation; Titanium | 2003 |
Periprosthetic osteolysis: induction of vascular endothelial growth factor from human monocyte/macrophages by orthopaedic biomaterial particles.
Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Biocompatible Materials; Cells, Cultured; Chemotaxis; DNA, Complementary; Extracellular Matrix Proteins; Female; Humans; In Vitro Techniques; Joint Prosthesis; Macrophages; Male; MAP Kinase Signaling System; Middle Aged; Models, Biological; Monocytes; Osteolysis; Prosthesis Failure; RNA, Messenger; Titanium; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1 | 2003 |
Spinal implant debris-induced osteolysis.
Topics: Adult; Animals; Apoptosis; Arthroplasty, Replacement; Humans; Inflammation; Interleukin-1; Interleukin-6; Macrophages; Microscopy, Electron, Transmission; Models, Biological; Osteoclasts; Osteolysis; Particle Size; Prostheses and Implants; Rabbits; Spine; Stainless Steel; Titanium; Tumor Necrosis Factor-alpha | 2003 |
PGE2 and IL-6 production by fibroblasts in response to titanium wear debris particles is mediated through a Cox-2 dependent pathway.
Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Fibroblasts; In Vitro Techniques; Interleukin-6; Isoenzymes; Mice; Mice, Inbred CBA; Osteolysis; Prostaglandin-Endoperoxide Synthases; Prosthesis Failure; Titanium | 2004 |
Effect of cyclic mechanical stretch and titanium particles on prostaglandin E2 production by human macrophages in vitro.
Topics: Cyclooxygenase 2; Dinoprostone; Equipment Failure Analysis; Humans; Isoenzymes; Joint Prosthesis; Kinetics; Macrophages; Membrane Proteins; Osteolysis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Stress, Mechanical; Titanium | 2004 |
Effects of interleukin-10 on titanium particle-induced macrophage transcription factor activation and cytokine expression in vitro.
Topics: CCAAT-Enhancer-Binding Protein-beta; Cytokines; Humans; Interleukin-10; Joint Prosthesis; Macrophage Activation; Macrophages; NF-kappa B; Osteolysis; Titanium | 2004 |
The effectiveness of polyethylene versus titanium particles in inducing osteolysis in vivo.
Topics: Animals; Disease Models, Animal; Female; Giant Cells, Foreign-Body; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Particle Size; Polyethylene; Skull; Titanium; Wound Healing | 2004 |
Wear-particle-induced osteoclast osteolysis: the role of particulates and mechanical strain.
Topics: Animals; Antibodies; Apoptosis; Bone Marrow; Carrier Proteins; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Chromium Alloys; Eicosanoids; Glycoproteins; Membrane Glycoproteins; Mice; Osteoclasts; Osteolysis; Osteoprotegerin; Particle Size; Plastics; Polyethylene; Rabbits; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Solubility; Stress, Mechanical; Surface Properties; Titanium | 2004 |
Wear of a highly cross-linked polyethylene liner associated with metallic deposition on a ceramic femoral head.
Topics: Aged; Aluminum Oxide; Arthroplasty, Replacement, Hip; Hip Dislocation; Humans; Male; Microscopy, Electron, Scanning; Osteolysis; Polyethylene; Prosthesis Failure; Radiography; Reoperation; Surface Properties; Titanium | 2004 |
The role of implant alignment on stability and particles on periprosthetic osteolysis--A rabbit model of implant failure.
Topics: Alloys; Animals; Arthroplasty; Foreign-Body Reaction; Implants, Experimental; Osteolysis; Polyethylenes; Prosthesis Failure; Rabbits; Tibia; Titanium | 2004 |
Proinflammatory mediator expression in a novel murine model of titanium-particle-induced intramedullary inflammation.
Topics: Animals; Biocompatible Materials; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Femur; Histocytochemistry; Inflammation Mediators; Interleukin-6; Macrophage Colony-Stimulating Factor; Mice; Organ Culture Techniques; Osteolysis; Prostheses and Implants; Radiography; Stainless Steel; Titanium; Tumor Necrosis Factor-alpha | 2004 |
Expression of inflammatory cytokines, RANKL and OPG induced by titanium, cobalt-chromium and polyethylene particles.
Topics: Animals; Biocompatible Materials; Carrier Proteins; Chromium Alloys; Foreign-Body Reaction; Gene Expression Regulation; Glycoproteins; Materials Testing; Membrane Glycoproteins; Men; Mice; Mice, Inbred C57BL; Microspheres; Osteolysis; Osteoprotegerin; Particle Size; Polyethylene; Prosthesis-Related Infections; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Titanium | 2005 |
Gene expression clustering using self-organizing maps: analysis of the macrophage response to particulate biomaterials.
Topics: Algorithms; Alloys; Biocompatible Materials; Cluster Analysis; DNA, Complementary; Down-Regulation; Gene Expression Regulation; Humans; Image Processing, Computer-Assisted; Inflammation; Ligands; Macrophages; Male; Monocytes; Multigene Family; Oligonucleotide Array Sequence Analysis; Osteolysis; Phagocytosis; Polyethylene; Polyethylenes; Prosthesis Failure; RNA, Messenger; Signal Transduction; Statistics as Topic; Time Factors; Titanium; Up-Regulation | 2005 |
Polyethylene and titanium particles induce osteolysis by similar, lymphocyte-independent, mechanisms.
Topics: Animals; Arthroplasty, Replacement; Cytokines; Lymphocytes; Mice; Mice, Inbred C57BL; Osteolysis; Polyethylene; Titanium | 2005 |
Ten to twelve-year results with the Zweymüller cementless total hip prosthesis.
Topics: Aged; Bone Cements; Ceramics; Equipment Failure Analysis; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Postoperative Complications; Prosthesis Design; Radiography; Reoperation; Titanium | 2005 |
Radiographic evaluation of a monoblock acetabular component: a multicenter study with 2- to 5-year results.
Topics: Acetabulum; Biomechanical Phenomena; Coated Materials, Biocompatible; Equipment Failure Analysis; Follow-Up Studies; Fracture Healing; Fractures, Bone; Hip Dislocation, Congenital; Hip Prosthesis; Humans; Osseointegration; Osteoarthritis, Hip; Osteolysis; Postoperative Complications; Prosthesis Design; Radiography; Tantalum; Titanium | 2005 |
Activation of NF-kappaB signalling and TNFalpha-expression in THP-1 macrophages by TiAlV- and polyethylene-wear particles.
Topics: Alloys; Arthroplasty, Replacement, Knee; Cells, Cultured; DNA; Humans; Macrophages; NF-kappa B; Osteolysis; Polyethylene; Promoter Regions, Genetic; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha | 2005 |
Sphingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis: a role for free radicals, NFkappaB, and TNFalpha.
Topics: Animals; Cell Line; Free Radicals; Glutathione; Macrophage Activation; Mice; NF-kappa B; Osteolysis; Phagocytosis; Sphingomyelin Phosphodiesterase; Titanium; Tumor Necrosis Factor-alpha | 2005 |
Re: the LPM Titanium semi-constrained proximal interphalangeal joint replacement.
Topics: Arthroplasty, Replacement; Finger Joint; Humans; Joint Prosthesis; Osteolysis; Titanium | 2006 |
Particulate endocytosis mediates biological responses of human mesenchymal stem cells to titanium wear debris.
Topics: Apoptosis; Arthroplasty, Replacement; Cell Adhesion; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cytochalasin D; Endocytosis; Humans; Joint Prosthesis; Mesenchymal Stem Cells; Microscopy, Confocal; Osteogenesis; Osteolysis; Titanium | 2006 |
Osteolysis caused by tibial component debonding in total knee arthroplasty.
Topics: Aged; Arthroplasty, Replacement, Knee; Bone Cements; Follow-Up Studies; Humans; Male; Osteolysis; Prosthesis Failure; Radiography; Reoperation; Tibia; Titanium | 2006 |
[Results of cementless hip arthroplasty].
Topics: Austria; Bone Cements; Follow-Up Studies; Germany; Hip Prosthesis; Humans; Osseointegration; Osteolysis; Patient Satisfaction; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium | 2006 |
Wear debris inhibition of anti-osteoclastogenic signaling by interleukin-6 and interferon-gamma. Mechanistic insights and implications for periprosthetic osteolysis.
Topics: Bone Cements; Cells, Cultured; Humans; Interferon-gamma; Interleukin-6; Joint Prosthesis; Mitogen-Activated Protein Kinases; Osteoclasts; Osteolysis; Polymethyl Methacrylate; Titanium | 2006 |
Metallosis after contemporary metal-on-metal total hip arthroplasty. Five to nine-year follow-up.
Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Hypersensitivity; Joint Diseases; Male; Middle Aged; Niobium; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Time Factors; Titanium; Vitallium | 2006 |
Involvement of complement receptor 3 (CR3) and scavenger receptor in macrophage responses to wear debris.
Topics: Fibronectins; Humans; Lipopolysaccharide Receptors; Macrophages; Monocytes; Opsonin Proteins; Osteolysis; Phagocytosis; Polymethacrylic Acids; Prosthesis Failure; Receptors, Complement 3b; RNA, Messenger; Scavenger Receptors, Class A; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha | 2006 |
The potential for bone loss in acetabular structures following THA.
Topics: Acetabulum; Arthroplasty, Replacement, Hip; Benzophenones; Biocompatible Materials; Biomechanical Phenomena; Chromium Alloys; Female; Finite Element Analysis; Hip Joint; Hip Prosthesis; Humans; Imaging, Three-Dimensional; In Vitro Techniques; Ketones; Middle Aged; Osteolysis; Polyethylene Glycols; Polyethylenes; Polymers; Prosthesis Design; Prosthesis Failure; Stress, Mechanical; Titanium | 2006 |
The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Bone Resorption; Cells, Cultured; Culture Media, Conditioned; Cytokines; Female; Fibroblasts; Gene Expression Regulation; Humans; Knee Prosthesis; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Osteoclasts; Osteolysis; Osteoprotegerin; Phagocytosis; RANK Ligand; RNA, Messenger; Titanium; Vascular Endothelial Growth Factor A | 2006 |
The balance between endotoxin accumulation and clearance during particle-induced osteolysis in murine calvaria.
Topics: Animals; Endotoxins; Female; Germ-Free Life; Mice; Mice, Inbred C57BL; Osteolysis; Polyethylene; Prosthesis Failure; Skull; Titanium | 2007 |
Wear-induced osteolysis and synovial swelling in a patient with a metal-polyethylene wrist prosthesis.
Topics: Adult; Corrosion; Humans; Joint Prosthesis; Lymphocytes; Macrophages; Male; Neutrophils; Osteolysis; Polyethylene; Prosthesis Failure; Reoperation; Stress, Mechanical; Synovitis; Titanium; Wrist Joint | 2006 |
Comparison of the roles of IL-1, IL-6, and TNFalpha in cell culture and murine models of aseptic loosening.
Topics: Animals; Antibodies; Asepsis; Cell Differentiation; Cells, Cultured; Female; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Osteoclasts; Osteolysis; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Titanium; Tumor Necrosis Factor-alpha | 2007 |
Radiolucent lines and osteolysis along tapered straight cementless titanium hip stems: a comparison of 6-year and 10-year follow-up results in 95 patients.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Joint Instability; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Titanium | 2006 |
Administration of pamidronate alters bone-titanium attachment in the presence of endotoxin-coated polyethylene particles.
Topics: Absorptiometry, Photon; Animals; Bone and Bones; Bone Density Conservation Agents; Diphosphonates; Endotoxins; Female; Femur; Hip Prosthesis; Injections, Intraperitoneal; Osteolysis; Pamidronate; Polyethylene; Rats; Rats, Sprague-Dawley; Titanium | 2007 |
Calvarial defects associated with neurofibromatosis type 1. Report of two cases.
Topics: Absorbable Implants; Adolescent; Bone Plates; Female; Head; Humans; Ilium; Imaging, Three-Dimensional; Male; Neurofibromatosis 1; Neurosurgical Procedures; Osteolysis; Skull; Surgical Mesh; Titanium; Tomography, X-Ray Computed | 2007 |
Evolution of tibial fixation in total knee arthroplasty.
Topics: Arthroplasty, Replacement, Knee; Cementation; Humans; Osteolysis; Prosthesis Failure; Tantalum; Titanium | 2007 |
Histomorphometric analysis of the intramedullary bone response to titanium particles in wild-type and IL-1R1 knock-out mice: a preliminary study.
Topics: Animals; Bone and Bones; Bone Nails; Femur; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Osteolysis; Prosthesis Failure; Receptors, Interleukin-1 Type I; Titanium | 2008 |
Second-generation proximally coated titanium femoral component: minimum 7-year results.
Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Male; Materials Testing; Middle Aged; Osseointegration; Osteolysis; Pain; Pain Measurement; Prospective Studies; Prosthesis Design; Radiography; Range of Motion, Articular; Recovery of Function; Time Factors; Titanium; Treatment Outcome | 2007 |
Use of a hydroxyapatite-coated stem in patients with Dorr Type C femoral bone.
Topics: Alloys; Arthroplasty, Replacement, Hip; Durapatite; Female; Femur; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osseointegration; Osteolysis; Prosthesis Design; Radiography; Range of Motion, Articular; Recovery of Function; Retrospective Studies; Time Factors; Titanium; Treatment Outcome | 2007 |
Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis.
Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cells, Cultured; Cytokines; Female; Femur; Gene Expression Profiling; Humans; Macrophages; Male; Middle Aged; Osteoarthritis, Hip; Osteoclasts; Osteogenesis; Osteolysis; Polymethyl Methacrylate; Prosthesis Failure; Reverse Transcriptase Polymerase Chain Reaction; Synovial Membrane; Titanium | 2008 |
Complex revision total hip arthroplasty with modular stems at a mean of 14 years.
Topics: Arthroplasty, Replacement, Hip; Bone Transplantation; Femur; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Joint Instability; Osseointegration; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Stress, Mechanical; Time Factors; Titanium; Treatment Outcome | 2007 |
Good stability and minimal osteolysis with a biconical threaded cup at 10 years.
Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cementation; Ceramics; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Joint Instability; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Retrospective Studies; Titanium | 2007 |
Severe bone defects and reduced mineralization caused by massive metallosis after total knee arthroplasty: histopathologic and bone morphometric findings.
Topics: Aged; Arthroplasty, Replacement, Knee; Bone Resorption; Calcification, Physiologic; Female; Foreign-Body Reaction; Humans; Osteogenesis; Osteolysis; Postoperative Complications; Prosthesis Failure; Radiography; Tetracycline; Tibia; Tibial Fractures; Titanium | 2007 |
Reducing metal debris generation during total knee arthroplasty.
Topics: Animals; Arthroplasty, Replacement, Knee; Disease Models, Animal; Equipment Design; Materials Testing; Osteolysis; Particle Size; Postoperative Complications; Swine; Titanium | 2007 |
Effect of component fixation method on osteolysis in total knee arthroplasty.
Topics: Aged; Aged, 80 and over; Alloys; Bone Cements; Bone Screws; Chromium Alloys; Follow-Up Studies; Humans; Knee Prosthesis; Middle Aged; Osteolysis; Postoperative Complications; Prosthesis Design; Radiography; Titanium | 1995 |
The potential role of fibroblasts in periprosthetic osteolysis: fibroblast response to titanium particles.
Topics: Base Sequence; Bone Resorption; Fibroblasts; Hip Prosthesis; Humans; Metalloendopeptidases; Molecular Sequence Data; Osteolysis; Protein Biosynthesis; Reference Values; RNA, Messenger; Stimulation, Chemical; Synovial Membrane; Titanium | 1995 |
Early failure of titanium alloy femoral components: a quantitative radiological analysis of osteolytic and granulomatous change.
Topics: Aged; Aged, 80 and over; Alloys; Femur; Granuloma; Hip Prosthesis; Humans; Middle Aged; Osteolysis; Prosthesis Failure; Radiography; Time Factors; Titanium; Vitallium | 1993 |
In vivo and in vitro analysis of membranes from hip prostheses inserted without cement.
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Bone Cements; Bone Resorption; Chromium Alloys; Collagenases; Dinoprostone; Female; Hip Prosthesis; Humans; Immunohistochemistry; Interleukin-1; Macrophage Activation; Macrophages; Male; Middle Aged; Osteolysis; Polyethylenes; Prosthesis Failure; Radiography; Reoperation; Titanium | 1994 |
Hip replacement with a threaded acetabular cup. A follow-up study.
Topics: Acetabulum; Adult; Aged; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium | 1994 |
The relationship between the design, position, and articular wear of acetabular components inserted without cement and the development of pelvic osteolysis.
Topics: Acetabulum; Adolescent; Adult; Aged; Body Fluids; Bone Cysts; Female; Follow-Up Studies; Foreign-Body Reaction; Hip Prosthesis; Humans; Hydrostatic Pressure; Ilium; Logistic Models; Male; Middle Aged; Osteolysis; Pelvic Bones; Polyethylenes; Porosity; Prosthesis Design; Prosthesis Failure; Prosthesis Fitting; Reoperation; Surface Properties; Titanium; Weight-Bearing | 1994 |
Extensive osteolysis around an aseptic, stable, uncemented total knee replacement.
Topics: Bone Cements; Chromium; Cobalt; Femur; Humans; Knee Prosthesis; Male; Middle Aged; Osteolysis; Polyethylenes; Prosthesis Failure; Synovial Membrane; Titanium | 1993 |
Osteolysis from a press-fit hydroxyapatite-coated implant. A case study.
Topics: Acetabulum; Durapatite; Female; Foreign-Body Migration; Hip Prosthesis; Humans; Hydroxyapatites; Microscopy, Electron, Scanning; Middle Aged; Osteoarthritis; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium | 1993 |
Metal/metal articulating interfaces.
Topics: Hip Prosthesis; Humans; Metals; Osteolysis; Polyethylenes; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Surface Properties; Titanium | 1995 |
Adsorption of collagenase to particulate titanium: a possible mechanism for collagenase localization in periprosthetic tissue.
Topics: Adsorption; Amino Acid Sequence; Animals; Biocompatible Materials; Cells, Cultured; Collagenases; Equipment Failure; Female; Joint Prosthesis; Kinetics; L-Lactate Dehydrogenase; Latex; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Osteolysis; Substrate Specificity; Time Factors; Titanium | 1994 |
Increasing incidence of femoral osteolysis in association with uncemented Harris-Galante total hip arthroplasty. A follow-up report.
Topics: Adult; Aged; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Radiography; Titanium | 1996 |
Titanium, chromium and cobalt ions modulate the release of bone-associated cytokines by human monocytes/macrophages in vitro.
Topics: Biocompatible Materials; Cell Division; Cells, Cultured; Chromium; Cobalt; Corrosion; Cytokines; Humans; Interleukin-1; Interleukin-6; Joint Prosthesis; Lymphoma, Large B-Cell, Diffuse; Macrophages; Monocytes; Osteolysis; Prosthesis Failure; Titanium; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha | 1996 |
Primary cementless hip arthroplasty with a titanium plasma sprayed prosthesis.
Topics: Adult; Aged; Arthritis, Rheumatoid; Cementation; Female; Femur Head Necrosis; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Retrospective Studies; Titanium | 1996 |
Radiographic analysis of a cemented titanium alloy femoral component.
Topics: Aged; Alloys; Bone Density; Bone Remodeling; Cementation; Female; Femur; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Design; Radiography; Titanium | 1997 |
Human monocyte/macrophage response to cobalt-chromium corrosion products and titanium particles in patients with total joint replacements.
Topics: Adult; Aged; Aged, 80 and over; Bone Resorption; Calcium; Cell Division; Cell Line; Cell Membrane; Cell Survival; Chromium; Cobalt; Corrosion; Culture Media, Conditioned; Dinoprostone; Female; Fibroblasts; Hip Prosthesis; Humans; Interleukin-1; Joint Instability; Macrophages; Male; Materials Testing; Metals; Middle Aged; Monocytes; Organ Culture Techniques; Osteolysis; Titanium | 1997 |
Three-dimensional polyethylene wear of a press-fit titanium prosthesis. Factors influencing generation of polyethylene debris.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Femur Head Necrosis; Follow-Up Studies; Hip; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Polyethylenes; Postoperative Complications; Prosthesis Design; Radiography; Regression Analysis; Risk Factors; Titanium | 1997 |
Results of the cementless Mallory-Head primary total hip arthroplasty: a 5 to 7 year review.
Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Polyethylenes; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium; Treatment Outcome | 1996 |
Prosthetic metals interfere with the functions of human osteoblast cells in vitro.
Topics: Bone Neoplasms; Cell Division; Chromium; Cobalt; Cytokines; Humans; Joint Prosthesis; Osteoblasts; Osteocalcin; Osteolysis; Osteosarcoma; Titanium; Tumor Cells, Cultured | 1997 |
Titanium prosthetic wear debris in remote bone marrow. A report of two cases.
Topics: Acetabulum; Aged; Aluminum; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone Marrow; Electron Probe Microanalysis; Female; Femoral Fractures; Fractures, Spontaneous; Hip Prosthesis; Humans; Knee Prosthesis; Male; Middle Aged; Osteolysis; Patella; Prosthesis Failure; Reoperation; Titanium; Vanadium | 1997 |
Total hip arthroplasty with an uncemented femoral component. Excellent results at ten-year follow-up.
Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Alloys; Arthroplasty, Replacement, Hip; Cementation; Connective Tissue; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Osseointegration; Osteolysis; Prosthesis Design; Prosthesis Failure; Prosthesis-Related Infections; Radiography; Reoperation; Sepsis; Surface Properties; Survival Rate; Titanium; Treatment Outcome | 1997 |
Short periods of oscillating fluid pressure directed at a titanium-bone interface in rabbits lead to bone lysis.
Topics: Animals; Bone and Bones; Disease Models, Animal; Hydrostatic Pressure; Osseointegration; Osteogenesis; Osteolysis; Pressure; Prostheses and Implants; Rabbits; Time Factors; Titanium | 1998 |
Experiences with metal on metal components in THR.
Topics: Alloys; Arthroplasty, Replacement, Hip; Ceramics; Chromium Alloys; Friction; Hip Prosthesis; Humans; Osteolysis; Polyethylenes; Prosthesis Design; Stress, Mechanical; Surface Properties; Titanium; Treatment Outcome | 1997 |
Acetabular osteolysis with cementless cups: a 5 to 7 year follow-up.
Topics: Acetabulum; Adult; Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cementation; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Hypertrophy; Joint Diseases; Male; Middle Aged; Osteolysis; Pain; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Stress, Mechanical; Titanium; Walking | 1997 |
The Furlong hydroxyapatite-coated total hip replacement in patients under age 51. A 6-year follow-up study.
Topics: Acetabulum; Adult; Age Factors; Alloys; Arthroplasty, Replacement, Hip; Biocompatible Materials; Chi-Square Distribution; Durable Medical Equipment; Durapatite; Female; Femoral Fractures; Femur; Follow-Up Studies; Hip Dislocation; Hip Prosthesis; Humans; Intraoperative Complications; Joint Instability; Male; Middle Aged; Osseointegration; Osteolysis; Pain; Patient Satisfaction; Polyethylenes; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Radiography; Range of Motion, Articular; Reoperation; Surface Properties; Titanium; Treatment Outcome | 1998 |
Particulate debris presenting as radiographic dense masses following total knee arthroplasty.
Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Humans; Male; Middle Aged; Osteoarthritis; Osteolysis; Prosthesis Failure; Radiography; Titanium | 1998 |
Fixation and metal release from the Tifit femoral stem prosthesis. 5-year follow-up of 64 cases.
Topics: Adult; Aged; Alloys; Arthroplasty, Replacement, Hip; Bone Cements; Coated Materials, Biocompatible; Durapatite; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Pain, Postoperative; Prosthesis Design; Prosthesis Failure; Radiography; Titanium | 1998 |
Induction of macrophage C-C chemokine expression by titanium alloy and bone cement particles.
Topics: Antibodies, Monoclonal; Bone Cements; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Chemokines, CC; Chemotaxis; Hip Prosthesis; Humans; Macrophage Inflammatory Proteins; Macrophages; Osteolysis; Prosthesis Failure; Titanium | 1999 |
A prospective review of 303 cementless universal cups with emphasis on wear as the cause of failure.
Topics: Adult; Aged; Aged, 80 and over; Evaluation Studies as Topic; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylenes; Prospective Studies; Prosthesis Design; Prosthesis Failure; Range of Motion, Articular; Reoperation; Stress, Mechanical; Titanium | 1994 |
SR-PLLA and SR-PGA miniscrews: biodegradation and tissue reactions in the calvarium and dura mater.
Topics: Absorbable Implants; Absorption; Animals; Biocompatible Materials; Biodegradation, Environmental; Bone Matrix; Bone Plates; Bone Remodeling; Bone Screws; Follow-Up Studies; Foreign-Body Reaction; Frontal Bone; Hydrolysis; Osteolysis; Osteotomy; Polyesters; Polyglycolic Acid; Radiography; Sheep; Time Factors; Titanium | 1999 |
The role of acetabular component screw holes and/or screws in the development of pelvic osteolysis.
Topics: Adult; Aged; Aged, 80 and over; Alloys; Bone Screws; Chromium; Cobalt; Follow-Up Studies; Hip Prosthesis; Humans; Incidence; Middle Aged; Osseointegration; Osteolysis; Pelvic Bones; Prosthesis Design; Prosthesis Failure; Radiography; Surface Properties; Titanium | 1999 |
Mechanism of failure in hips with an uncemented, all polyethylene socket.
Topics: Acetabulum; Alloys; Arthroplasty, Replacement, Hip; Cementation; Female; Femur; Follow-Up Studies; Foreign Bodies; Hip Prosthesis; Humans; Macrophages; Male; Middle Aged; Osteolysis; Particle Size; Polyethylenes; Prosthesis Design; Prosthesis Failure; Reoperation; Retrospective Studies; Titanium; Treatment Outcome | 1999 |
The acetabular component in total hip arthroplasty. Evaluation of different fixation principles.
Topics: Absorbable Implants; Acetabulum; Adult; Aged; Arthroplasty, Replacement, Hip; Biocompatible Materials; Biomechanical Phenomena; Bone Cements; Bone Screws; Calcium Phosphates; Case-Control Studies; Ceramics; Data Interpretation, Statistical; Durapatite; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Orthopedic Fixation Devices; Osteolysis; Prosthesis Design; Prosthesis Failure; Randomized Controlled Trials as Topic; Spectrophotometry, Atomic; Time Factors; Titanium | 1999 |
Migration of polyethylene particles around stable implants in an animal model.
Topics: Alloys; Animals; Disease Models, Animal; Foreign-Body Migration; Implants, Experimental; Knee Prosthesis; Osteolysis; Particle Size; Polyethylene; Rabbits; Titanium | 1999 |
Tumor necrosis factor-alpha/nuclear transcription factor-kappaB signaling in periprosthetic osteolysis.
Topics: Animals; Arthroplasty, Replacement; Cell Line; Female; Immunohistochemistry; Macrophages; Male; Mice; Mice, Inbred CBA; NF-kappa B; Osteoclasts; Osteolysis; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha | 2000 |
Osteolysis in cemented titanium alloy hip prosthesis.
Topics: Adult; Aged; Aged, 80 and over; Alloys; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Survival Analysis; Titanium | 2000 |
Serial measurement of polyethylene wear of well-fixed cementless metal-backed acetabular component in total hip arthroplasty: an over 10 year follow-up study.
Topics: Acetabulum; Adult; Aged; Alloys; Analysis of Variance; Arthritis, Rheumatoid; Arthroplasty, Replacement, Hip; Chromium Alloys; Coated Materials, Biocompatible; Femur Head; Femur Head Necrosis; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Image Processing, Computer-Assisted; Middle Aged; Osteoarthritis; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Risk Factors; Stress, Mechanical; Surface Properties; Time Factors; Titanium | 2000 |
Efficacy of etanercept for wear debris-induced osteolysis.
Topics: Animals; Arthroplasty, Replacement; Cell Line; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Etanercept; Immunoglobulin G; Interleukin-6; Mice; Mice, Inbred CBA; Osteoclasts; Osteolysis; Receptors, Tumor Necrosis Factor; Titanium; Tumor Necrosis Factor-alpha | 2001 |
The effects of particulate wear debris, cytokines, and growth factors on the functions of MG-63 osteoblasts.
Topics: Biocompatible Materials; Cell Line; Chromium; Cytokines; Gene Expression Regulation; Growth Substances; Humans; In Vitro Techniques; Joint Prosthesis; Multivariate Analysis; Osteoblasts; Osteolysis; Phagocytosis; Plastics; RNA, Messenger; Titanium | 2001 |
Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis.
Topics: Animals; Bone Resorption; Celecoxib; Cells, Cultured; Crosses, Genetic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Interleukin-1; Interleukin-6; Isoenzymes; Macrophage Activation; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Osteoclasts; Osteolysis; Prostaglandin-Endoperoxide Synthases; Prostheses and Implants; Prosthesis Failure; Pyrazoles; Skull; Sulfonamides; Titanium; Tumor Necrosis Factor-alpha | 2001 |
Rapid repair of titanium particle-induced osteolysis is dramatically reduced in aged mice.
Topics: Aging; Animals; Female; Mice; Mice, Inbred C57BL; Osteolysis; Parietal Bone; Time Factors; Titanium; Wound Healing | 2001 |
A retrieval study of capital hip prostheses with titanium alloy femoral stems.
Topics: Aged; Aged, 80 and over; Device Removal; Female; Granulation Tissue; Hip Prosthesis; Humans; Male; Middle Aged; Necrosis; Osteolysis; Reoperation; Titanium | 2001 |
In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis.
Topics: Acid Phosphatase; Animals; Bone Matrix; Bone Remodeling; Bone Resorption; Female; Fluoresceins; Glycoproteins; Mice; Mice, Inbred CBA; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Signal Transduction; Skull; Titanium | 2002 |
Hydroxyapatite-coated stems with metaphyseal and diaphyseal press-fit. Eleven-year follow-up results.
Topics: Aged; Alloys; Arthroplasty, Replacement, Hip; Biocompatible Materials; Biomechanical Phenomena; Durapatite; Female; Follow-Up Studies; Hip; Humans; Male; Middle Aged; Osteolysis; Pain; Postoperative Complications; Prosthesis Design; Survival Analysis; Titanium | 2002 |
Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis.
Topics: Animals; Animals, Newborn; beta-Galactosidase; Cells, Cultured; Culture Media, Conditioned; Disease Models, Animal; Female; Fibroblasts; Genetic Therapy; Glycoproteins; Lac Operon; Mice; Mice, Inbred CBA; Osteoclasts; Osteolysis; Osteoprotegerin; Prostheses and Implants; Prosthesis Failure; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Skull; Titanium; Transduction, Genetic | 2002 |
Clinical experiences with a titanium alloy total hip prosthesis: a posterior approach.
Topics: Adult; Aged; Female; Femoral Fractures; Femur Neck; Hepatitis; Hip Dislocation; Hip Joint; Hip Prosthesis; Humans; Leg Length Inequality; Locomotion; Male; Methods; Middle Aged; Movement; Osteolysis; Paralysis; Postoperative Complications; Surgical Wound Infection; Thromboembolism; Titanium | 1979 |
Titanium wear debris in failed cemented total hip arthroplasty. An analysis of 71 cases.
Topics: Adult; Aged; Aged, 80 and over; Cementation; Female; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Failure; Radiography; Reoperation; Titanium | 1992 |
Aseptic loosening in total hip arthroplasty secondary to osteolysis induced by wear debris from titanium-alloy modular femoral heads.
Topics: Femur Head; Hip Prosthesis; Humans; Osteolysis; Prosthesis Failure; Titanium | 1991 |
Histologic, biochemical, and ion analysis of tissue and fluids retrieved during total hip arthroplasty.
Topics: Aluminum; Dinoprostone; Hip Joint; Hip Prosthesis; Humans; Interleukin-2; Ions; Metals; Microbial Collagenase; Osteolysis; Polyethylenes; Radiography; Titanium; Vanadium | 1990 |
Cementless total joint arthroplasty prostheses with titanium-alloy articular surfaces. A human retrieval analysis.
Topics: Adolescent; Adult; Aged; Alloys; Foreign Bodies; Hip Joint; Hip Prosthesis; Humans; Knee Prosthesis; Middle Aged; Osteolysis; Polyethylenes; Titanium | 1990 |
Aseptic loosening in total hip arthroplasty secondary to osteolysis induced by wear debris from titanium-alloy modular femoral heads.
Topics: Adult; Alloys; Corrosion; Female; Femur Head; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Failure; Radiography; Reoperation; Synovial Membrane; Titanium | 1989 |