Page last updated: 2024-08-22

titanium and Osteolysis

titanium has been researched along with Osteolysis in 309 studies

Research

Studies (309)

TimeframeStudies, this research(%)All Research%
pre-19902 (0.65)18.7374
1990's40 (12.94)18.2507
2000's77 (24.92)29.6817
2010's128 (41.42)24.3611
2020's62 (20.06)2.80

Authors

AuthorsStudies
Ha, YC; Kim, HS; Koo, KH; Lee, SJ; Lee, YK; Park, JW1
Chen, Z; Ding, Y; Kuang, M; Li, C; Li, S; Lin, C; Lin, S; Ouyang, Z; Wen, Z; Xue, C1
Hu, W; Sun, Y; Yu, Y; Yuan, F; Zhao, F1
Diao, L; Liu, M; Liu, X; Mao, Y; Shi, X; Yang, X; Zhang, Y; Zhao, F; Zhou, J1
Geng, D; Gu, Y; Li, W; Liang, X; Liu, X; Liu, Y; Peng, X; Tao, Y; Wang, L; Wang, Q; Wang, T; Wu, Z; Xu, Y; Zhang, H; Zhang, W; Zhou, J1
Dorodi, O; Ghanbari, N; Jousheghan, SS; Panahi, M; Qoreishi, M1
Cao, J; Fu, Y; Gong, A; Li, Y; Liu, L; Ma, X; Wu, Y; Yang, Z; Zhang, G; Zhang, L; Zhao, Y1
Gao, X; Ge, J; Geng, D; Xu, L; Zhou, W1
Chi, Y; Gao, J; Mao, Y; Song, N; Wu, P; Xu, H; Zhao, Y1
Bai, J; Chen, L; Geng, D; Gu, Y; Li, M; Li, W; Liang, X; Liu, X; Tao, Y; Wang, H; Wang, T; Wang, W; Wu, Z; Yang, H; Zhang, W; Zhou, J1
Chai, H; Fang, JY; Geng, C; She, C; Xu, W; Zhang, ZH1
García González, E; Martínez Villén, G; Rodríguez Nogué, L1
Cao, W; Dong, J; Jiang, Q; Lv, Z; Ruan, B; Wang, H; Wang, Y; Zhang, L1
Cheng, X; Deng, J; Miao, X; Pan, C; Pan, H; Wang, X1
Chen, S; Feng, C; Geng, D; Gu, M; Li, W; Li, Y; Ma, Y; Wang, Z; Xiao, L; Yang, Y1
Ding, Y; Gao, L; Li, C; Li, S; Li, X; Lin, S; Luo, W; Wang, X; Wen, Z; Wu, C1
Ding, Y; Huang, Y; Li, C; Li, S; Lin, S; Liu, T; Ouyang, Z; Sun, Y; Xu, J; Zeng, G; Zheng, Z1
Cheng, Y; Han, Z; He, S; Li, L; Lin, J; Liu, N; Teng, Y; Wu, Y; Yang, H; Zhang, S; Zhao, Z1
Chai, H; Geng, D; Huang, Q; Jiao, Z; Sun, C; Wang, S; Xu, W1
Du, G; Huang, N; Jiang, J; Kang, J; Ning, B; Sun, Z; Yang, S; Zhang, X; Zhang, Y1
Jia, C; Li, H; Li, W; Li, Y; Liu, B; Liu, H; Liu, L; Liu, Y; Liu, Z; Nie, L; Sun, X; Wang, Y; Xu, Z; Yu, R; Yuan, Y; Zhang, P; Zhao, Y1
Kang, J; Tan, Y; Xiao, W; Xie, X; Yang, D1
Choi, H; Ihn, HJ; Kim, JA; Kim, JE; Lim, S; Moon, J; Park, EK; Yea, K1
Cao, L; Chen, X; Li, L; Li, Y; Li, Z; Qiu, W; Su, Z; Zhang, W1
Chen, DS; Liu, Y; Liu, ZG; Wang, WP; Xie, YL; Yuan, A; Zhang, C; Zhao, JB1
Chen, L; Gu, X; Luo, H; Qu, Y; Si, M; Tong, Z1
Bai, J; Ge, G; Geng, D; Lin, J; Wang, L; Wang, Q; Wang, Y; Xu, C; Xu, N; Xu, Y1
Cheng, T; Qian, Y; Yang, C; Yuan, X; Zhang, X; Zhu, K1
Chai, H; Fang, JY; Geng, C; Huang, Q; Jia, P; Jia, XY; She, C; Xu, W; Zhang, ZH1
Deng, F; Fu, T; Fu, X; Hu, X; Huang, J; Ji, P; Jiang, L; Song, J; Wu, X; Xu, L; Yang, Z; Zhang, Z; Zhou, P1
Chen, X; Cheng, Y; Fan, B; Wei, X; Yu, S; Zhang, A; Zhang, S; Zhao, H1
Chen, Z; Ding, Y; Fang, G; Fu, Y; Kuang, M; Li, C; Li, S; Lin, S; Mao, J; Peng, P; Qin, L; Qiu, J; Wen, Z; Xin, M1
Cai, Z; Li, D; Ma, R; Qiu, M; Su, B; Sun, H; Xu, J1
Jiang, J; Jiang, S; Li, D; Yang, S1
Bai, J; Ge, G; Geng, D; Guo, X; Lin, J; Liu, Y; Qu, Q; Shen, J; Shi, J; Tao, Y; Xu, Y; Yang, H; Yu, B1
Liu, W; Qian, Y; Shan, H; Yang, C; Yu, X; Zeng, B; Zhang, X1
Chen, J; Hong, D; Lei, X; Li, B; Li, M; Liao, Z; Liu, Q; Yang, H; Yang, Y; Zhang, L; Zhang, Z; Zhu, M1
Gao, Y; Ma, H; Shi, J; Sun, C; Zhang, Q; Zhang, W1
Chen, HF; Feng, K; Ge, YW; Liu, XL; Liu, ZQ; Mao, YQ; Sun, ZY; Wang, CF; Wang, HW; Yu, DG; Zhang, JW1
Bai, J; Geng, D; Guo, X; Lin, J; Liu, Y; Pan, G; Shen, J; Sun, H; Wang, D; Xu, M; Yu, B; Zhang, H1
Ding, Y; Guo, D; Guo, H; Huang, J; Li, Y; Lin, S; Liu, P; Liu, Q; Liu, Y; Luo, P; Ma, Y; Mo, G; Qiu, H; Qiu, J; Tang, Y; Wen, Z; Xu, J; Xu, L; Yuan, J; Zhang, S; Zhou, T1
Dong, F; Li, H; Lian, Y; Liao, Y; Liu, H; Lu, D; Wang, Y; Wu, J; Zhang, Z1
Gang, F; Jiang, L; Lin, J; Liu, Z; Shi, W; Sun, X; Wang, X; Wang, Y; Wei, Y; Xu, N; Zhao, L; Zhu, X1
He, F; Lin, J; Yang, H; Zhang, Y; Zhu, X1
Gao, XR; Ge, J; Geng, DQ; Li, WY; Xu, L; Zhou, WC1
Bai, J; Ge, G; Geng, D; Liang, X; Liu, B; Wang, Q; Wang, W; Wei, M; Xu, Y; Yang, H; Yang, S; Zhang, W; Zheng, K1
Ding, X; Feng, W; Kc, A; Liang, J; Liao, S; Lin, X; Liu, Q; Liu, Y; Song, F; Song, H; Su, Y; Wang, Z; Xu, J; Zhao, J1
Bai, J; Feng, C; Ge, G; Geng, D; Qin, J; Tang, W; Wang, Z; Wei, M; Xiao, L; Zhang, W; Zhong, M; Zhu, J; Zhu, X1
Deng, Z; Fu, G; Jin, J; Li, M; Li, S; Liu, C; Lyu, FJ; Ma, Y; Wang, S; Zheng, Q1
Chen, D; Guo, F; Li, Y; Liu, Z; Song, G; Yang, J; Zhang, C1
Deng, Z; Fu, G; Jin, J; Li, M; Ma, Y; Wang, S; Wang, Z; Zhang, R; Zheng, Q1
García-Cimbrelo, E; García-Rey, E; Saldaña, L; Vallés, G; Vilaboa, N1
Geng, T; Guo, H; Jin, Q; Lu, Z; Sun, K; Wang, B; Zhang, L1
Huang, Q; Huang, W; Lei, G; Li, Q; Liu, Y; Wu, H; Xiao, J; Yang, M; Yin, Y; Zhou, K1
Bai, J; Geng, D; Gu, Y; Shi, J; Tao, Y; Wang, Y; Xiong, L; Xu, Y; Xue, Y; Yang, H; Ye, H1
Madsen, F; Petersen, ET; Stilling, M; Søballe, K; Thillemann, JK; Torle, J1
Bai, J; Ge, G; Geng, D; Gu, Y; Li, N; Li, X; Sun, H; Wang, W; Wang, Z; Xu, Y; Xue, Y; Zhang, W; Zheng, K; Zhou, J1
Chen, J; Liao, Z; Sun, S; You, H; Zhang, L; Zhao, G1
Chen, W; Gu, M; Pan, B; Sheng, P; Wu, X; Xian, G; Ye, Y; Zhang, Z; Zheng, L1
Ge, G; Geng, D; Jiang, S; Wang, L; Wang, Q; Wang, W; Wang, Y; Xu, N; Xu, Y; Zhao, G; Zheng, D; Zhu, R1
He, F; Jin, Z; Lin, J; Lin, W; Liu, A; Shi, W; Su, X; Wu, Y; Yang, H; Zhang, C; Zhang, Q; Zhu, X1
Shang, GQ; Wang, P; Wang, YZ; Xiang, S; Xu, H; Zhang, HN1
Chen, C; He, J; Hu, S; Jin, Y; Rui, Y; Shi, Q; Sun, J; Xue, Y; Zhang, Y1
Li, X; Sun, Y; Wang, J; Yan, L; Zhang, Z; Zhao, S1
Hussey, DK; McGrory, BJ1
Chughtai, M; Delanois, RE; Gwam, CU; Khlopas, A; Malkani, AL; Mohamed, N; Mont, MA1
DiVincenzo, MJ; Frydman, GH; Jennings, SH; Kowaleski, MP; Lai, B; Oura, TJ; Vanderburg, CR1
Jiao, Z; Qin, A; Shen, P; Xu, W; Yang, C; Zhang, S; Zheng, J1
Fernández-Fernández, R; Gil-Garay, E; Martínez-Miranda, JM1
Chen, X; Geng, T; Guo, H; Jin, Q; Sun, S; Wang, B; Zhang, S1
Du, Z; Wang, Y; Zhu, Z1
Chen, L; Chu, B; Fan, Y; Feng, M; Hong, D; Hong, Z; Li, Z; Lv, H; Yuan, C; Zhang, L; Zhu, M1
Chen, Y; Li, B; Li, J; Li, Y; Peng, X; Yuan, X1
Jeon, JG; Kim, JE; Kim, JS; Lee, MH; Park, IS; Takanche, JS; Yi, HK1
Gao, ZY; Guo, CC; Lv, CY; Wang, CY; Wang, YZ; Xu, H; Yin, ZY; Zhang, HN1
Ding, Y; Geng, D; Guo, X; Liu, Y; Shi, J; Wang, L; Wu, X; Xu, Y; Yang, H; Zhou, W1
Cai, W; Ding, Y; Fu, G; Li, C; Li, S; Luo, M; Peng, P; Qin, L; Qiu, J; Zhang, C1
Pritchett, JW1
Feng, W; Huang, H; Li, F; Li, G; Li, J; Liao, S; Liu, Y; Ma, S; Wei, Q; Wei, Y; Yao, J; Zhong, C1
Fini, M; Martini, L; Parrilli, A; Sartori, M; Tschon, M; Veronesi, F1
Feng, K; Ge, YW; Liu, ZQ; Mao, YQ; Sun, ZY; Yu, DG; Zhu, ZA1
Liang, T; Lu, Q; Nong, X; Wei, C; Wei, G; Zhao, J1
Ding, Y; Fu, G; Li, C; Li, S; Liu, W; Ouyang, N; Peng, P; Qin, L; Qiu, J; Wu, J1
Benazzo, F; Cuzzocrea, F; Ferranti, E; Fioruzzi, A; Ivone, A; Jannelli, E; Vanelli, R1
Carmi, Y; Eger, M; Gabet, Y; Hiram-Bab, S; Kohavi, D; Liron, T; Sterer, N1
Dai, K; Huang, Y; Tang, J; Yang, F1
Feng, WY; Liao, SJ; Lin, XX; Liu, Q; Liu, Y; Ma, ST; Moro, A; Song, FM; Wang, ZY; Xu, J; Zhan, XL; Zhao, JM1
Atkins, GJ; Crotti, TN; Findlay, DM; Haynes, DR; Ormsby, RT; Solomon, LB; Yang, D1
Awiszus, F; Feuerstein, B; Goldau, G; Hameister, R; Klutzny, M; Lohmann, CH; Singh, G; Stärke, C1
Perni, S; Prokopovich, P; Rivera, MC; Sloan, A1
Ding, X; Feng, W; Liao, S; Lin, X; Liu, Q; Liu, Y; Ma, S; Song, F; Song, H; Wang, Z; Xu, J; Yao, J; Zhao, J1
Chang, L; Li, W; Wang, F; Wang, X1
Cai, W; Chen, Z; Ding, Y; Fang, G; Fu, Y; Li, C; Li, S; Lin, S; Mao, J; Peng, P; Qin, L; Qiu, J1
Chen, X; Hayball, J; Li, P; Li, W; Li, Y; Liu, L; Qiu, C; Qu, R; Vasilev, K; Wang, W; Yuan, Y; Zhang, Z; Zhao, Y1
Cho, HS; Ihn, HJ; Kim, K; Park, EK1
Hong, Y; Liao, L; Lin, Y; Liu, Q; Ni, J; Yu, S; Zhang, Z; Zhong, Y1
Gong, W; Jia, T; Jiang, Y; Wooley, PH; Yang, SY1
Capello, WN; D'Antonio, JA; Naughton, M1
Baxter, RM; Connor, PM; Day, JS; Kurtz, SM; Morrey, BF; Ramsey, ML; Steinbeck, MJ1
Ding, Y; Guan, ZP; Huang, DS; Huang, JB; Zeng, WK; Zhang, ML1
Guo, H; Hao, S; Jin, Q; Ma, X; Sun, S; Yang, X; Yu, B1
Fischer, L; Obando-Pereda, GA; Stach-Machado, DR1
Agarwal, S; Azam, A; Morgan-Jones, R1
Liu, S; Ross, RD; Sena, K; Sumner, DR; Virdi, AS1
Dai, K; Fan, Q; Li, H; Liu, X; Ouyang, Z; Qin, A; Qu, X; Tang, T; Tian, B; Wang, W; Wu, C; Xu, X; Zhai, Z1
Baad-Hansen, T; Bonefeld, CM; Gustafson, K; Jakobsen, SS; Johansen, JD; Lorenzen, ND; Stilling, M; Søballe, K; Thyssen, JP1
Fan, Q; Gu, D; Jiang, C; Li, H; Liu, X; Ouyang, Z; Qin, A; Qu, X; Tang, T; Xiao, F; Zhai, Z1
Ellison, P; Grosse, S; Hallan, G; Haugland, HK; Høl, PJ; Lilleng, P1
Cui, J; Geng, D; Liu, X; Shao, H; Xu, Y; Yang, H; Yu, L; Zhang, W; Zhu, S1
Dai, K; Fan, Q; Jiang, Q; Jiang, T; Li, H; Liu, X; Ouyang, Z; Qin, A; Shao, Z; Tang, T; Tian, B; Yu, Y; Zhai, Z; Zheng, M; Zhu, Z1
Aquarius, R; Buma, P; Schreurs, BW; Verdonschot, N; Walschot, LH1
Hong, JM; Ihn, HJ; Kim, JA; Kim, SH; Kim, SY; Lim, J; Park, EK; Park, JY; Shin, HI1
Ang, ES; Chim, SM; Ding, Y; Feng, H; Huang, J; Liu, Q; Pavlos, N; Tan, RX; Tickner, J; Wu, H; Xu, J; Xue, W; Ye, J; Zhao, J; Zhou, L1
Fan, Q; Li, H; Liu, F; Liu, X; Qin, A; Qu, X; Tang, T; Tian, B; Wang, W; Wu, C; Zhai, Z; Zhu, Z1
Jiang, C; Liu, X; Mao, Y; Ouyang, Z; Qin, A; Qu, X; Tang, T; Tian, B; Wang, W; Wu, C; Zhai, Z; Zhu, Z1
Dai, K; Gu, X; Jiang, C; Liu, X; Qin, A; Tang, T; Wang, J; Wang, W; Wang, Y; Xiao, F; Zhai, Z; Zhu, Z1
Chen, D; Guo, F; Hei, C; Jin, Q; Li, P; Li, Y; Lu, Z1
Bao, N; Cao, L; Fang, Y; Sun, Y; Wang, B; Wang, Q; Xiong, C; Zhang, Z; Zhao, J1
Frydman, A; Simonian, K1
Cui, J; Geng, D; Shao, H; Shen, J; Wang, M; Wang, Y; Xu, Y; Yang, H; Zhang, W; Zhu, S1
Jang, SP; Kim, DW; Lim, SJ; Moon, YW; Park, YS1
Choi, YH; Im, SU; Lee, YE; Park, EK; Park, KS; Song, KB1
Chen, S; Fan, SW; Hu, ZJ; Huang, KM; Jin, G; Ma, JJ; Ma, Y; Qin, A; Tang, XZ; Wang, JY; Wang, Q; Zhou, ZJ1
Geng, D; Hu, X; Ping, Z; Shao, H; Wang, Y; Wu, J; Xu, Y; Yang, H; Zhang, W; Zhu, S; Zhu, X1
Berger, RA; Della Valle, CJ; Jacobs, JJ; Paprosky, WG; Plummer, DR; Sporer, SM1
Dong, W; Geng, L; Li, M; Qin, A; Qin, Y; Wang, W; Zhang, M; Zhang, X1
Bao, N; Gan, J; Guo, T; Liu, N; Qian, H; Shi, T; Wang, Z; Zhao, J; Zhou, G1
Bao, N; Gan, J; Guo, T; Liu, N; Qian, H; Shi, T; Wang, R; Wang, Z; Zhao, J; Zhou, G1
Hall, DJ; Jacobs, JJ; Pourzal, R; Skipor, AK; Turner, TM; Urban, RM1
Geng, D; Gu, Y; Hu, X; Ping, Z; Shao, H; Wang, L; Wang, Y; Xu, Y; Yang, H; Zhang, W; Zhu, M1
Chen, HX; Fan, YY; Feng, MX; Hong, D; Hong, JX; Lei, XH; Qin, A; Wang, Q; Yuan, CT; Zhu, M1
Chen, KH; Huang, KC; Hung, LK; Lee, CH; Shih, CM; Su, KC1
Einhorn, TA; Liu, AT; Liu, CJ; Tian, QY; Wei, JL; Yi, YS; Zhao, YP1
Chen, W; Guo, Y; Li, C; Li, Z; Luo, G; Sheng, P; Wang, H; Wang, Y; Xiao, Y; Zhang, Y; Zhang, Z1
Bechtel, CP; Gebhart, JJ; Greenfield, EM; Kiss-Toth, E; Tatro, JM; Wilkinson, JM1
Chen, L; Deng, ZL; He, MS; Li, H; Liao, Y; Liu, Y; Wang, C; Wang, Y; Wu, NN; Zhang, RX1
Liu, N; Meng, J; Shi, T; Wang, Z; Zhao, J; Zhou, G1
Lachiewicz, PF; Soileau, ES2
Geng, D; Hu, X; Ping, Z; Shi, J; Tao, Y; Wang, J; Wang, L; Wang, Y; Wu, X; Xu, Y; Yang, H; Zhang, W1
Delank, KS; Floerkemeier, T; Frecher, S; Grupp, TM; Jäger, M; Puente Reyna, AL; Schilling, C1
Dai, J; He, J; Li, X; Sun, Y; Wang, D; Wang, J; Wang, S; Yan, L; Zhang, Z; Zhao, S1
Ding, Y; Huang, DS; Huang, JB; Qin, CQ; Song, B; Zhang, C1
He, R; Jiang, S; Xue, D; Ye, C; Yu, Y; Zhang, W; Zhou, X; Zhu, L1
Gan, M; Geng, D; Hu, X; Ping, Z; Shi, J; Tao, Y; Wang, L; Wang, Z; Wu, X; Xu, Y; Yang, H; Zhang, W1
Bao, N; Deng, Z; Gao, Q; Jin, J; Wang, Y; Wang, Z; Zhao, J1
Hasegawa, Y; Higuchi, Y; Ishiguro, N; Komatsu, D; Seki, T1
Eger, M; Gabet, Y; Kohavi, D; Liron, T; Sterer, N1
Chakraborty, C; Chang, JD; Jagga, S; Lee, DH; Lee, SS; Lee, YH; Nam, JS; Nguyen, LT; Sharma, AR; Sharma, G1
Geng, D; Guo, X; Hou, Z; Hu, X; Ping, Z; Shi, J; Tao, Y; Wang, L; Wang, Z; Wu, X; Xu, Y; Yang, H; Zhang, W1
Deng, LF; Fan, WS; Guo, CA; Kang, H; Wang, YM; Yan, ZQ; Zhu, L1
Bian, Z; He, Q; Li, M; Tian, F; Wang, X; Yao, W; Zhu, L1
Bonar, SF; Kirsh, G; Murali, R; Walter, WK; Walter, WL1
Hubbard, JB; Lachiewicz, PF; Soileau, ES1
Ihle, M; Mai, S; Pfluger, D; Siebert, W1
Assini, JB; Biant, LC; Bruce, WJ; Walker, PM; Walsh, WR1
Beksaç, B; González Della Valle, A; Salas, A; Salvati, EA1
Rahbek, O; Stilling, M; Søballe, K1
Bresson, D; Chauvet, D; Chibbaro, S; Di Emidio, P; Galzio, R; George, B; Makiese, O; Mirone, G1
Bailey, MJ; Clanchy, FI; De Kok, B; Graves, SE; Hamilton, JA; Haynes, D; Lacey, DC; Speed, K1
Bukata, SV; Darowish, M; Flick, LM; Gelinas, J; Huang, W; Li, P; O'Keefe, RJ; Rahman, R; Schwarz, EM1
Alanen, K; Kohonen, I; Koivu, H; Sipola, E; Tiusanen, H; Vahlberg, T1
Altenburg, AJ; Brown, TD; Callaghan, JJ; Dahl, KA; Goetz, DD; Johnston, RC; Leinen, JA; Liu, SS; Pedersen, DR; Yehyawi, TM1
Araki, Y; Harada, H; Kagiya, T; Kimura, S; Narushima, T; Nezu, T; Sasaki, M; Taira, M1
Krieg, AH; Ochsner, PE; Speth, BM1
Gong, W; Jia, T; Wooley, PH; Yang, SY; Yu, H; Zhang, L; Zhang, T1
Galley, MR; Meding, JB; Ritter, MA1
Zhang, C; Zhang, P; Zhou, X; Zhu, Z1
Geng, D; Wang, J; Wang, X; Xu, Y; Yang, H; Zhu, G; Zhu, X1
Cai, XZ; Li, R; Yan, SG; Zhu, FB; Zhu, HX1
Asou, Y; Denhardt, DT; Kato, N; Muneta, T; Noda, M; Okawa, A; Okuda, N; Rittling, SR; Shimizu, S; Shinomiya, K; Tsuji, K1
Eastell, R; Gordon, A; Greenfield, EM; Kiss-Toth, E; Wilkinson, JM1
Lv, D; Sun, ML; Wang, HB; Zhu, L1
Forke, L; Irlenbusch, U; Lorenz, U1
Hawkins, M; Markel, DC; Ren, W; Shi, T; Zhang, R1
Geng, DC; Wang, XB; Xu, YZ; Yang, HL; Zhu, GM; Zhu, XS1
Ayers, DC; Chan, M; Finberg, RW; Iwakura, Y; Kurt-Jones, EA; St Pierre, CA1
Bourne, RB; Charron, KD; Corten, K; MacDonald, SJ; McCalden, RW; Teo, Y1
Belt, EA; Ikävalko, M; Kautiainen, H; Kokkonen, A; Tiihonen, R1
Bai, L; McQueen, DA; Song, Z; Wooley, PH; Yang, SY; Yu, H; Zhang, K1
Cheng, T; Peng, X; Zhang, W; Zhang, X1
Cahir, J; Chirodian, N; Derbyshire, B; Macnair, R; Toms, A; Wimhurst, J; Wynn-Jones, H1
Greenfield, EM; Schnaser, EA; Smith, MV; Tatro, JM; Wu, D1
Bourne, RB; Brandt, JM; Burnell, CD; Petrak, MJ1
Chen, L; Geng, D; Huang, C; Mao, H; Wang, J; Xu, Y; Yang, H; Zhu, X1
Hong, JM; Jin, S; Kim, SY; Kim, TH; Park, EK; Park, JY; Shin, HI1
Cheng, T; Peng, X; Zhang, W; Zhang, X; Zhao, H1
Bader, R; Fritsche, A; Hansmann, D; Jonitz, A; Lochner, K; Mueller, P; Mueller-Hilke, B1
Celil Aydemir, AB; Chung, KJ; Hsu, AC; Jacobs, CR; Kim, KO; Lee, FY; Lee, HG; Minematsu, H; Nizami, SA; Shin, MJ1
Hasty, KA; Marlar, J; Schwab, LP; Smith, RA1
Cheng, T; Mao, X; Pan, X; Zhang, X1
Argintar, E; Bush, C; Chen, FH; Haleem-Smith, H; Hampton, D; Lamb, J; Postma, WF; Rimington, T; Tuan, RS1
García-Cimbrelo, E; Vallés, G; Vilaboa, N1
Cheng, T; Mao, X; Pan, X; Peng, X; Zhang, X; Zhao, S1
Beecher, B; Glassner, P; Kwon, YM; Malchau, H1
Cao, L; Cheng, TS; Chim, SM; Dai, KR; Lin, Z; Pavlos, NJ; Qin, A; Xu, J; Zheng, MH1
Kim, MH; Kim, SY; Kim, TH; Lee, SH; Shin, DK1
Ding, Y; Fu, YR; Huang, DS; Qin, CQ; Xu, J1
Chen, D; Guo, Y; Mao, X; Zhang, X1
Ecker, TM; Murphy, SB; Tannast, M1
Masri, B; Noordin, S1
Chen, D; Cheng, T; Guo, Y; Mao, X; Pan, X; Shi, S; Zhang, X1
Back, DA; Haas, NP; Kaeppler, K; Pauly, S; Schmidmaier, G; Wildemann, B1
Anderson, JA; Beksac, B; Bruni, D; Poultsides, LA; Sculco, TP; Sioros, V1
Carmody, EE; O'Keefe, RJ; Puzas, JE; Rosier, RN; Schwarz, EM1
Corbeil, J; Du, P; Genini, D; Leoni, L; Pioletti, DP; Takei, H1
Emerson, CB; Emerson, RH; Head, WC; Higgins, LL; Rosenfeldt, W1
Rosson, JW; Sott, AH1
Cunningham, BW; Dmitriev, AE; Hallab, NJ; McAfee, PC; Orbegoso, CM; Sefter, JC1
Foguet, P; Hashmi, F; Lawrence, T1
Pace, TB; Rizzo, M1
Ebramzadeh, E; Gruen, TA; Llinás, A; McKellop, HA; Normand, PL; Sangiorgio, SN; Sarmiento, A1
Hasegawa, Y; Ishiguro, N; Kitamura, S; Sakano, S; Warashina, H; Yamaguchi, J; Yamauchi, KI1
Jenny, JY1
Goodman, SB; Ma, T; Miyanishi, K; Schurman, DJ; Smith, RL; Trindade, MC1
Cunningham, BW; Hallab, NJ; Jacobs, JJ1
Bukata, SV; Gelinas, J; Griswold, DE; O'Keefe, RJ; Puzas, JE; Rosier, RN; Schwarz, EM; Song, XY; Wei, X; Zhang, X1
Akisue, T; Fujishiro, T; Kurosaka, M; Nishikawa, T; Shibanuma, N; Takikawa, S; Yamamoto, T; Yoshiya, S1
Goodman, SB; Patel, R; Smith, RL; Trindade, MC; Wong, N; Yaszay, B1
Berry, DJ; Jewison, DE; Loer, F; Morrey, BF; Scully, SP; Sibonga, JD; Sprecher, C; von Knoch, M1
Anderson, GI; Coles, C; Fang Chen, Y; MacQuarrie, RA1
Della Valle, AG; Doty, S; Gradl, G; Labissiere, A; Nestor, BJ1
Fornasier, VL; Goodman, SB; Kamel, M; Protzner, K; Shojaci, A; Song, Y1
Epstein, NJ; Goodman, SB; Ma, T; Miyanishi, K; Regula, D; Saket, RR; Smith, RL; Trindade, MC; Warme, BA1
Hasegawa, Y; Ishiguro, N; Masui, T; Sakano, S; Warashina, H1
Cho, DR; Garrigues, GE; Goldring, SR; Herndon, JH; Rubash, HE; Shanbhag, AS1
Goldberg, VM; Greenfield, EM; Nalepka, JL; Rimnac, CM; Taki, N; Tatro, JM; Togawa, D1
Anderson, PG; Koetsier, JW; Louwerse, RT; Van Hout, F; Vervest, TM; Wapstra, FH1
Gruen, TA; Hanssen, AD; Lewallen, DG; Lewis, RJ; O'Keefe, TJ; Poggie, RA; Stulberg, SD; Sutherland, CJ1
Baumann, B; Eulert, J; Jakob, F; Nöth, U; Rader, CP; Rolf, O; Seufert, J1
Darowish, M; O'Keefe, RJ; Schwarz, EM; Soloviev, A1
Giddins, G; Hobby, J1
Haleem-Smith, H; Laqueriere, P; Manner, PA; Okafor, CC; Tuan, RS1
Cheng, K; Pruitt, L; Ries, MD; Zaloudek, C1
Grübl, A1
Ivashkiv, LB; Ly, K; Nestor, BJ; Purdue, PE; Rakshit, DS; Sculco, TP; Sengupta, TK1
Korovessis, P; Petsinis, G; Repanti, M; Repantis, T1
Ivashkiv, LB; Lim, JT; Ly, K; Nestor, BJ; Purdue, PE; Rakshit, DS; Sculco, TP1
Kurtz, SM; Manley, MT; Ong, KL1
Gál, I; Glant, TT; Jacobs, JJ; Koreny, T; Tunyogi-Csapó, M; Vermes, C1
Doerschuk, CM; Goldberg, VM; Greenfield, EM; Islam, AS; Rimnac, CM; Stewart, MC; Taki, N; Tatro, JM1
Gosens, T; Groot, D; Leeuwen, NC; Rhee, MV; Teepen, HJ1
Goldberg, VM; Greenfield, EM; Lowe, R; Taki, N; Tatro, JM1
Schwarzinger, UM; Steindl, MS; Zweymüller, KA1
Hasty, KA; Smith, RA; Xing, Z1
Greene, AK; McNeely, PD; Mislow, JM; Proctor, MR; Rogers, GF1
Berasi, CC; Berend, KR; Lombardi, AV1
Bragg, B; Epstein, NJ; Goodman, S; Ma, T; Smith, RL1
Bryant, P; Lachiewicz, PF; Soileau, ES1
Bierbaum, BE; Bono, JV; Kelly, SJ; Robbins, CE; Ward, DM1
Bostrom, MP; Ivashkiv, LB; Koulouvaris, P; Ly, K; Nestor, BJ; Purdue, PE; Sculco, TP1
Lee, JA; McCarthy, JC1
Schwarzinger, U; Steindl, M; Zweymüller, KA1
Gejo, R; Kimura, T; Matsushita, I; Morita, Y1
Bell, CG; Crawford, R; Pickering, SA; Sydney, SE1
Barrack, RL; Ezzet, KA; Garcia, R1
Galante, JO; Glant, TT; Hoerrner, LA; Hutchinson, NI; Jacobs, JJ; Kuettner, KE; Lark, MW; Mikecz, K; Yao, J1
Stiles, PJ; Unwin, AJ1
Chiba, J; Kim, KJ; Rubash, HE1
Fox, GM; Heiner, JP; McBeath, AA1
Amstutz, HC; Grecula, M; Guttmann, D; Schmalzried, TP1
Berry, DJ; Rand, JA; Wold, LE1
Bloebaum, RD; Dupont, JA1
Böhler, N1
Beebe, JD; DeHeer, DH; Kane, KR; Owens, SR; Swanson, AB1
Maloney, WJ; Woolson, ST1
Gustilo, RB; Tsukayama, DT; Wang, JY; Wicklund, BH2
Eng, K; Hozack, WJ; Mesa, J; Rothman, RH1
Faris, PM; Herbst, SA; Keating, EM; Meding, JB; Ritter, MA1
Brennan, FR; Glant, TT; Jacobs, JJ; Lee, SH; Ragasa, DR; Urban, RM1
Betts, F; Doty, SB; Evans, BG; Salvati, EA1
Coldham, G; Devane, PA; Horne, JG; Krause, B; Martin, K1
Bourne, RB; Mulliken, BD; Nayak, N; Rorabeck, CH2
Bourne, RB; Devane, PA; Horne, JG; Nayak, NN; Robinson, EJ; Rorabeck, CH1
Engh, CA; Engh, GA; Moore, KD; Vinh, TN1
Lee, KR; McLaughlin, JR1
Aspenberg, P; de Kleine, R; Tigchelaar, W; van der Vis, H; van Noorden, CJ1
Boehler, N1
Hyde, ID; Loupasis, G; Morris, EW1
Herrington, SM; Lombardi, AV; Mallory, TH; Staab, M1
Frech, W; Herberts, P; Kärrholm, J; Malchau, H; Nivbrant, B; Snorrason, F1
Chun, LE; Goodman, SB; Maloney, WJ; Nakashima, Y; Schurman, DJ; Smith, RL; Song, Y; Sun, DH; Trindade, MC1
Beight, J; Cautilli, GP; Hozack, WJ; Yao, B1
Hallikainen, D; Helevirta, P; Peltoniemi, HH; Toivonen, T; Waris, T1
Amstutz, HC; Brown, IC; Engh, CA; Harris, WH; Schmalzried, TP1
Campbell, P; Ebramzadeh, E; Llinás, A; McKellop, HA; Park, SH; Sarmiento, A1
Thanner, J1
Bookman, I; Davey, JR; Kreder, HK; Yee, AJ1
Fisher, J; Ingham, E1
Beals, N; Bearcroff, J; Lalor, PA; Mitchell, SL; Namba, R; Sledge, CB; Spector, M1
Benz, EB; Goater, JJ; Kollias, G; Lu, AP; O'Keefe, RJ; Puzas, JE; Rosier, RN; Schwarz, EM1
Eggli, S; Ganz, R; Schöll, E1
Ando, M; Baba, H; Dai, X; Hashimoto, N; Oki, H; Okumura, Y; Omori, H1
Childs, LM; Goater, JJ; O'Keefe, RJ; Schwarz, EM1
Chandrasekaran, R; Galante, JO; Glant, TT; Jacobs, JJ; Roebuck, KA; Vermes, C1
Boyce, BF; Langenbach, R; Morham, SG; O'Keefe, RJ; Puzas, EJ; Rosier, RN; Schwarz, EM; Xing, L; Young, DA; Zhang, X1
Bi, Y; Carter, JR; Goldberg, VM; Greenfield, EM; Jinno, T; Kaar, SG; Kaye, SJ; Kilic, BA; Ragab, AA; Stewart, MC1
Andrews, M; Fisher, J; Ingham, E; Ivory, J; Mcgrath, LR; Shardlow, DL; Stone, MH1
Anderson, D; Boskey, AL; Boyce, BF; Childs, LM; Dougall, WC; O'Keefe, RJ; Paschalis, EP; Puzas, JE; Rosier, RN; Schwarz, EM; Xing, L1
Hernández Cortés, P; Hernández Hernández, MA; Mesa Ramos, F; Nájera Sagastume, OO; Pajares López, M1
Goater, JJ; O'Keefe, RJ; Puzas, JE; Rosier, RN; Schwarz, EM1
Latta, LL; Sarmiento, A; Tarr, RR; Zych, GA1
Bansal, M; Brien, W; Buly, RL; Huo, MH; Salvati, E1
Harris, WH1
Bloebaum, R; Dorr, LD; Emmanual, J; Meldrum, R1
Amstutz, HC; Campbell, PA; Kilgus, D; Kossovsky, N; Nasser, S1
Drouillard, P; Lombardi, AV; Mallory, TH; Vaughn, BK1

Reviews

6 review(s) available for titanium and Osteolysis

ArticleYear
Involvement of NF-κB/NLRP3 axis in the progression of aseptic loosening of total joint arthroplasties: a review of molecular mechanisms.
    Naunyn-Schmiedeberg's archives of pharmacology, 2022, Volume: 395, Issue:7

    Topics: Arthroplasty; Cytokines; Humans; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Osteoclasts; Osteolysis; Titanium

2022
Titanium particles in peri-implantitis: distribution, pathogenesis and prospects.
    International journal of oral science, 2023, Nov-23, Volume: 15, Issue:1

    Topics: Dental Implants; Humans; Inflammation; Osteolysis; Peri-Implantitis; Titanium

2023
Review of models for titanium as a foreign body.
    Journal of the California Dental Association, 2014, Volume: 42, Issue:12

    Topics: Dental Implants; Dental Materials; Dental Restoration Failure; Foreign Bodies; Foreign-Body Reaction; Humans; Hypersensitivity; Osteolysis; Solubility; Titanium

2014
Periprosthetic osteolysis: genetics, mechanisms and potential therapeutic interventions.
    Canadian journal of surgery. Journal canadien de chirurgie, 2012, Volume: 55, Issue:6

    Topics: Adaptive Immunity; Animals; Arthroplasty, Replacement; Bone Resorption; Humans; Joint Prosthesis; Osteogenesis; Osteolysis; Polymethyl Methacrylate; Prosthesis Failure; Titanium

2012
Particulate debris in cemented total hip replacement.
    Instructional course lectures, 1994, Volume: 43

    Topics: Biocompatible Materials; Bone Cements; Chromium Alloys; Hip Prosthesis; Humans; Macrophages; Metals; Osteolysis; Particle Size; Polyethylenes; Prosthesis Design; Prosthesis Failure; Synovial Fluid; Titanium

1994
Biological reactions to wear debris in total joint replacement.
    Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 2000, Volume: 214, Issue:1

    Topics: Biocompatible Materials; Bone Cements; Ceramics; Cytokines; Foreign Bodies; Hip Joint; Hip Prosthesis; Humans; Macrophages; Metals; Osteolysis; Particle Size; Polyethylenes; Polymethyl Methacrylate; Prosthesis Failure; Titanium

2000

Trials

7 trial(s) available for titanium and Osteolysis

ArticleYear
Less polyethylene wear in monobloc compared to modular ultra-high-molecular-weight-polyethylene inlays in hybrid total knee arthroplasty: A 5-year randomized radiostereometry study.
    The Knee, 2021, Volume: 29

    Topics: Adult; Aged; Arthroplasty, Replacement, Knee; Bone Screws; Female; Follow-Up Studies; Humans; Knee Prosthesis; Male; Middle Aged; Osteoarthritis, Knee; Osteolysis; Polyethylenes; Prospective Studies; Prosthesis Design; Radiostereometric Analysis; Tibia; Titanium

2021
Metal release and metal allergy after total hip replacement with resurfacing versus conventional hybrid prosthesis.
    Acta orthopaedica, 2014, Volume: 85, Issue:4

    Topics: Arthroplasty, Replacement, Hip; Chromium; Cobalt; Female; Follow-Up Studies; Hip Prosthesis; Humans; Hypersensitivity; Lymphocyte Activation; Male; Metals; Middle Aged; Nanoparticles; Osteolysis; Patch Tests; Polyethylene; Prosthesis Failure; Surveys and Questionnaires; Titanium

2014
Polyethylene wear and osteolysis with a new modular titanium acetabular component: results at 7 to 13 years.
    The Journal of arthroplasty, 2008, Volume: 23, Issue:7

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Biocompatible Materials; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prospective Studies; Prosthesis Failure; Titanium; Young Adult

2008
Inferior survival of hydroxyapatite versus titanium-coated cups at 15 years.
    Clinical orthopaedics and related research, 2009, Volume: 467, Issue:11

    Topics: Aged; Arthroplasty, Replacement, Hip; Coated Materials, Biocompatible; Durapatite; Equipment Safety; Female; Follow-Up Studies; Hip Prosthesis; Humans; Joint Instability; Kaplan-Meier Estimate; Male; Materials Testing; Middle Aged; Osteoarthritis, Hip; Osteolysis; Probability; Prospective Studies; Prosthesis Design; Prosthesis Failure; Risk Assessment; Statistics, Nonparametric; Time Factors; Titanium; Treatment Outcome

2009
A comparison of cemented and cementless titanium femoral components used for primary total hip arthroplasty: a radiographic and survivorship study.
    The Journal of arthroplasty, 2002, Volume: 17, Issue:5

    Topics: Acetabulum; Arthroplasty, Replacement, Hip; Cementation; Equipment Failure Analysis; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Osteolysis; Prosthesis Design; Reoperation; Titanium

2002
Measurement of polyethylene wear in acetabular components inserted with and without cement. A randomized trial.
    The Journal of bone and joint surgery. American volume, 1997, Volume: 79, Issue:5

    Topics: Acetabulum; Adult; Aged; Bone Cements; Computer Simulation; Double-Blind Method; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Image Processing, Computer-Assisted; Male; Materials Testing; Middle Aged; Models, Anatomic; Osteoarthritis, Hip; Osteolysis; Polyethylenes; Prospective Studies; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium

1997
A randomized trial of hydroxyapatite coated prostheses in total hip arthroplasty.
    Clinical orthopaedics and related research, 1999, Issue:366

    Topics: Acetabulum; Age Factors; Aged; Alloys; Arthroplasty, Replacement, Hip; Biocompatible Materials; Coated Materials, Biocompatible; Durapatite; Female; Femur; Follow-Up Studies; Foreign-Body Migration; Hip Prosthesis; Humans; Hyperostosis; Linear Models; Male; Middle Aged; Osteolysis; Porosity; Prospective Studies; Prosthesis Design; Radiography; Sex Factors; Surface Properties; Titanium

1999

Other Studies

296 other study(ies) available for titanium and Osteolysis

ArticleYear
High Risk of Neck-liner Impingement and Notching Observed with Thick Femoral Neck Implants in Ceramic-on-ceramic THA.
    Clinical orthopaedics and related research, 2022, Apr-01, Volume: 480, Issue:4

    Topics: Adult; Arthroplasty, Replacement, Hip; Ceramics; Femur Neck; Hip Joint; Hip Prosthesis; Humans; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Reproducibility of Results; Retrospective Studies; Titanium; Treatment Outcome

2022
LncRNA Neat1 promotes the macrophage inflammatory response and acts as a therapeutic target in titanium particle-induced osteolysis.
    Acta biomaterialia, 2022, 04-01, Volume: 142

    Topics: Animals; Inflammation; Joint Prosthesis; Macrophages; Mice; NF-kappa B; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; RNA, Long Noncoding; Titanium

2022
MiR-25 overexpression inhibits titanium particle-induced osteoclast differentiation via down-regulation of mitochondrial calcium uniporter in vitro.
    Journal of orthopaedic surgery and research, 2022, Mar-03, Volume: 17, Issue:1

    Topics: Calcium; Calcium Channels; Cell Differentiation; Down-Regulation; Humans; MicroRNAs; Osteoclasts; Osteolysis; RANK Ligand; RNA, Messenger; Titanium

2022
Piperlongumine Inhibits Titanium Particles-Induced Osteolysis, Osteoclast Formation, and RANKL-Induced Signaling Pathways.
    International journal of molecular sciences, 2022, Mar-05, Volume: 23, Issue:5

    Topics: Animals; Bone Resorption; Dioxolanes; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Signal Transduction; Titanium

2022
GSK-3β suppression upregulates Gli1 to alleviate osteogenesis inhibition in titanium nanoparticle-induced osteolysis.
    Journal of nanobiotechnology, 2022, Mar-19, Volume: 20, Issue:1

    Topics: Glycogen Synthase Kinase 3 beta; Hedgehog Proteins; Humans; Nanoparticles; Osteogenesis; Osteolysis; Titanium; Zinc Finger Protein GLI1

2022
Cortistatin attenuates titanium particle-induced osteolysis through regulation of TNFR1-ROS-caspase-3 signaling in osteoblasts.
    Annals of the New York Academy of Sciences, 2022, Volume: 1513, Issue:1

    Topics: Animals; Caspase 3; Mice; Mice, Inbred C57BL; Neuropeptides; Osteoblasts; Osteoclasts; Osteolysis; Reactive Oxygen Species; Receptors, Tumor Necrosis Factor, Type I; Titanium

2022
IL-10 inhibits osteoclast differentiation and osteolysis through MEG3/IRF8 pathway.
    Cellular signalling, 2022, Volume: 95

    Topics: Animals; Cell Differentiation; Interferon Regulatory Factors; Interleukin-10; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Polymethyl Methacrylate; Prosthesis Failure; RANK Ligand; RNA; RNA, Long Noncoding; Signal Transduction; Titanium

2022
LY450139 Inhibited Ti-Particle-Induced Bone Dissolution via Suppressing Notch and NF-κB Signaling Pathways.
    Calcified tissue international, 2022, Volume: 111, Issue:2

    Topics: Alanine; Animals; Azepines; Bone Resorption; Disease Models, Animal; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Signal Transduction; Solubility; Titanium

2022
NOX4 blockade suppresses titanium nanoparticle-induced bone destruction via activation of the Nrf2 signaling pathway.
    Journal of nanobiotechnology, 2022, May-23, Volume: 20, Issue:1

    Topics: Animals; Mice; Mice, Inbred C57BL; NADPH Oxidase 4; Nanoparticles; NF-E2-Related Factor 2; Osteogenesis; Osteolysis; Reactive Oxygen Species; Signal Transduction; Titanium

2022
Osteocytic cells exposed to titanium particles increase sclerostin expression and inhibit osteoblastic cell differentiation mostly via direct cell-to-cell contact.
    Journal of cellular and molecular medicine, 2022, Volume: 26, Issue:15

    Topics: Adaptor Proteins, Signal Transducing; Cell Differentiation; Connexin 43; Interleukin-6; Osteoblasts; Osteocytes; Osteolysis; Titanium; Tumor Necrosis Factor-alpha

2022
Postoperative assessment and management of metallosis and periprosthetic osteolysis in patients treated with metal-on-polyethylene total wrist prostheses.
    The Journal of hand surgery, European volume, 2022, Volume: 47, Issue:9

    Topics: Chromium; Cobalt; Humans; Metals; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Titanium; Wrist

2022
NRF2 is a critical regulator and therapeutic target of metal implant particle-incurred bone damage.
    Biomaterials, 2022, Volume: 288

    Topics: Animals; Mice; Mice, Inbred C57BL; Mice, Knockout; NF-E2-Related Factor 2; Osteoclasts; Osteolysis; Prostheses and Implants; Titanium

2022
Bimetallic Metal-Organic Framework for Mitigating Aseptic Osteolysis.
    ACS applied materials & interfaces, 2023, Feb-01, Volume: 15, Issue:4

    Topics: Humans; Macrophages; Metal-Organic Frameworks; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Reactive Oxygen Species; Titanium

2023
The Dopamine D1 Receptor Attenuates Titanium Particle-Induced Inhibition of Osteogenesis by Activating the Wnt Signaling Pathway.
    Mediators of inflammation, 2023, Volume: 2023

    Topics: Dopamine; Humans; Osteoclasts; Osteogenesis; Osteolysis; Receptors, Dopamine D1; Titanium; Wnt Signaling Pathway

2023
HUCMSC-derived Exosomes Suppress the Titanium Particles-induced Osteolysis in Mice through Inhibiting CCL2 and CCL3.
    Orthopaedic surgery, 2023, Volume: 15, Issue:3

    Topics: Animals; Chemokine CCL2; Chemokine CCL3; Exosomes; Humans; Mice; Osteolysis; Titanium

2023
STING/TBK1 Regulates Inflammation in Macrophages and Titanium Particles-Induced Osteolysis.
    ACS biomaterials science & engineering, 2023, 06-12, Volume: 9, Issue:6

    Topics: Animals; Inflammation; Macrophages; Mice; NF-kappa B; Osteolysis; Titanium

2023
Quercetin alleviates nanoparticle-induced osteolysis
    Biomaterials science, 2023, Jun-27, Volume: 11, Issue:13

    Topics: Animals; Humans; Inflammasomes; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Pyroptosis; Quercetin; Reactive Oxygen Species; Titanium

2023
Osteocytes Exposed to Titanium Particles Inhibit Osteoblastic Cell Differentiation via Connexin 43.
    International journal of molecular sciences, 2023, Jun-29, Volume: 24, Issue:13

    Topics: Animals; beta Catenin; Cell Differentiation; Connexin 43; Mice; Osteoblasts; Osteocytes; Osteolysis; Titanium

2023
CD73 inhibits titanium particle-associated aseptic loosening by alternating activation of macrophages.
    International immunopharmacology, 2023, Volume: 122

    Topics: 5'-Nucleotidase; Adenosine; Humans; Inflammation; Macrophages; Osteolysis; Titanium

2023
Selenomethionine against titanium particle-induced osteolysis by regulating the ROS-dependent NLRP3 inflammasome activation via the β-catenin signaling pathway.
    Frontiers in immunology, 2023, Volume: 14

    Topics: 3T3 Cells; Animals; beta Catenin; Inflammasomes; Inflammation; Mice; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; Reactive Oxygen Species; Selenomethionine; Signal Transduction; Titanium

2023
Zingerone attenuates Ti particle-induced inflammatory osteolysis by suppressing the NF-κB signaling pathway in osteoclasts.
    International immunopharmacology, 2023, Volume: 115

    Topics: Humans; NF-kappa B; Osteoclasts; Osteolysis; Signal Transduction; Titanium

2023
Britanin inhibits titanium wear particle‑induced osteolysis and osteoclastogenesis.
    Molecular medicine reports, 2023, Volume: 28, Issue:5

    Topics: Actin Cytoskeleton; Animals; Disease Models, Animal; Humans; Mice; Osteoclasts; Osteogenesis; Osteolysis; Titanium

2023
Kaempferol prevents aseptic loosening via enhance the Wnt/β-catenin signaling pathway in vitro and in vivo.
    European journal of medical research, 2023, Nov-09, Volume: 28, Issue:1

    Topics: Animals; beta Catenin; Cell Differentiation; Cells, Cultured; Core Binding Factor Alpha 1 Subunit; Kaempferols; Mice; Osteogenesis; Osteolysis; Prospective Studies; Titanium; Wnt Signaling Pathway

2023
The JNK signaling pathway against titanium-particle-induced osteoclastogenesis and bone resorption in vivo.
    European review for medical and pharmacological sciences, 2023, Volume: 27, Issue:21

    Topics: Animals; Bone Resorption; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Titanium

2023
Inhibition of protein phosphatase 2A attenuates titanium-particle induced suppression of bone formation.
    International journal of biological macromolecules, 2020, Jan-01, Volume: 142

    Topics: 3T3 Cells; Animals; beta Catenin; Cell Differentiation; Disease Models, Animal; Male; Mice; Mice, Inbred C57BL; Okadaic Acid; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Protein Phosphatase 2; Skull; Titanium; Wnt Signaling Pathway

2020
Curcumin has immunomodulatory effects on RANKL-stimulated osteoclastogenesis in vitro and titanium nanoparticle-induced bone loss in vivo.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:2

    Topics: Actins; Animals; Bone Resorption; Cell Death; Cell Differentiation; Cell Polarity; Curcumin; Cytokines; Immunomodulation; Macrophages; Male; Mice; Mice, Inbred C57BL; Models, Biological; Nanoparticles; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; Phosphorylation; Protective Agents; Proto-Oncogene Proteins c-akt; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium; Up-Regulation

2020
Reduction of SOST gene promotes bone formation through the Wnt/β-catenin signalling pathway and compensates particle-induced osteolysis.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:7

    Topics: 3T3 Cells; Adaptor Proteins, Signal Transducing; Animals; beta Catenin; Bone Regeneration; Cell Differentiation; Mice; Osteoblasts; Osteoclasts; Osteocytes; Osteogenesis; Osteolysis; Skull; Titanium; Wnt Signaling Pathway

2020
Nanosized Alumina Particle and Proteasome Inhibitor Bortezomib Prevented inflammation and Osteolysis Induced by Titanium Particle via Autophagy and NF-κB Signaling.
    Scientific reports, 2020, 03-27, Volume: 10, Issue:1

    Topics: Aluminum Oxide; Animals; Autophagy; Bortezomib; Cell Line; Cytokines; Humans; Inflammation; Male; Mice; Mice, Inbred C57BL; Nanoparticles; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Proteasome Inhibitors; Signal Transduction; Titanium

2020
DAPT inhibits titanium particle-induced osteolysis by suppressing the RANKL/Notch2 signaling pathway.
    Journal of biomedical materials research. Part A, 2020, 11-01, Volume: 108, Issue:11

    Topics: Amyloid Precursor Protein Secretases; Animals; Cells, Cultured; Diamines; Enzyme Inhibitors; Mice, Inbred C57BL; Osteolysis; Prostheses and Implants; RANK Ligand; Receptor, Notch2; Signal Transduction; Thiazoles; Titanium

2020
ZBTB20-mediated titanium particle-induced peri-implant osteolysis by promoting macrophage inflammatory responses.
    Biomaterials science, 2020, Jun-07, Volume: 8, Issue:11

    Topics: Aged; Aged, 80 and over; Animals; Arthroplasty, Replacement, Hip; Cells, Cultured; Cytokines; Female; Hip Prosthesis; Humans; Macrophages; Male; Mice, Inbred C57BL; Mice, Nude; Middle Aged; NF-kappa B; Osteolysis; Prosthesis Failure; Reoperation; Skull; Synovial Membrane; Titanium; Transcription Factors

2020
Exosomal lncRNAs NONMMUT000375.2 and NONMMUT071578.2 derived from titanium particle treated RAW264.7 cells regulate osteogenic differentiation of MC3T3-E1 cells.
    Journal of biomedical materials research. Part A, 2020, 11-01, Volume: 108, Issue:11

    Topics: Animals; Biocompatible Materials; Cell Line; Exosomes; Mice; Osteoclasts; Osteogenesis; Osteolysis; RAW 264.7 Cells; RNA, Long Noncoding; Titanium

2020
[Establishment of artificial joint aseptic loosening mouse model by cobalt-chromium particles stimulation].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2020, May-15, Volume: 34, Issue:5

    Topics: Animals; Chromium; Cobalt; Male; Mice; Mice, SCID; Osteolysis; Prosthesis Failure; Titanium

2020
MiR-106b inhibition suppresses inflammatory bone destruction of wear debris-induced periprosthetic osteolysis in rats.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:13

    Topics: Animals; Bone and Bones; Bone Resorption; Cell Count; Cell Polarity; Cytokines; Inflammation; Kidney; Liver; Macrophages; Male; MicroRNAs; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Phosphatidylinositol 3-Kinases; Prostheses and Implants; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; RANK Ligand; Rats, Sprague-Dawley; Signal Transduction; Titanium

2020
Naringin inhibits titanium particles-induced up-regulation of TNF-α and IL-6 via the p38 MAPK pathway in fibroblasts from hip periprosthetic membrane.
    Connective tissue research, 2021, Volume: 62, Issue:5

    Topics: Fibroblasts; Flavanones; Humans; Interleukin-6; NF-kappa B; Osteoclasts; Osteolysis; p38 Mitogen-Activated Protein Kinases; Titanium; Tumor Necrosis Factor-alpha; Up-Regulation

2021
Genetic and pharmacological activation of Hedgehog signaling inhibits osteoclastogenesis and attenuates titanium particle-induced osteolysis partly through suppressing the JNK/c-Fos-NFATc1 cascade.
    Theranostics, 2020, Volume: 10, Issue:15

    Topics: Animals; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Gene Knock-In Techniques; Hedgehog Proteins; JNK Mitogen-Activated Protein Kinases; Macrophages; Male; Mice; Mice, Inbred C57BL; Morpholines; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proto-Oncogene Proteins c-fos; Purines; Rabbits; Repressor Proteins; Signal Transduction; Titanium

2020
Enalapril inhibits inflammatory osteolysis induced by wear debris in a mouse model.
    The Journal of international medical research, 2020, Volume: 48, Issue:6

    Topics: Animals; China; Disease Models, Animal; Enalapril; Female; Inflammation; Mice; Mice, Inbred BALB C; Osteoclasts; Osteolysis; Prostheses and Implants; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2020
The Recombinant Protein EphB4-Fc Changes the Ti Particle-Mediated Imbalance of OPG/RANKL via EphrinB2/EphB4 Signaling Pathway and Inhibits the Release of Proinflammatory Factors In Vivo.
    Oxidative medicine and cellular longevity, 2020, Volume: 2020

    Topics: Actins; Animals; Bone Resorption; Cell Differentiation; Ephrin-B2; Female; Humans; Inflammation Mediators; Interleukin-1beta; Interleukin-6; Mice, Inbred C57BL; NFATC Transcription Factors; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Proto-Oncogene Proteins c-fos; RANK Ligand; Receptor, EphB4; Recombinant Proteins; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha

2020
Efficient Inhibition of Wear-Debris-Induced Osteolysis by Surface Biomimetic Engineering of Titanium Implant with a Mussel-Derived Integrin-Targeting Peptide.
    Advanced biosystems, 2019, Volume: 3, Issue:2

    Topics: Animals; Biomimetic Materials; Bivalvia; Catechols; Cells, Cultured; Coated Materials, Biocompatible; Femur; Integrin alphaVbeta3; Joint Prosthesis; Macrophages; Male; Mice; Mice, Inbred C57BL; Oligopeptides; Osteogenesis; Osteolysis; RANK Ligand; Rats, Sprague-Dawley; Titanium

2019
Carnosol suppresses RANKL-induced osteoclastogenesis and attenuates titanium particles-induced osteolysis.
    Journal of cellular physiology, 2021, Volume: 236, Issue:3

    Topics: Abietanes; Animals; Bone Resorption; Calcium Signaling; Female; Gene Expression Regulation; Male; MAP Kinase Signaling System; Mice, Inbred C57BL; Models, Biological; NF-kappa B; NF-KappaB Inhibitor alpha; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proteolysis; RANK Ligand; Skull; Titanium

2021
5-Aza-2-deoxycytidine inhibits osteolysis induced by titanium particles by regulating RANKL/OPG ratio.
    Biochemical and biophysical research communications, 2020, 08-27, Volume: 529, Issue:3

    Topics: Animals; Base Sequence; Blotting, Western; CpG Islands; Decitabine; DNA Methylation; Gene Expression; Male; Mice, Inbred BALB C; Osteolysis; Osteoprotegerin; Particle Size; RANK Ligand; Reverse Transcriptase Polymerase Chain Reaction; Skull; Titanium; X-Ray Microtomography

2020
Dual directions to address the problem of aseptic loosening via electrospun PLGA @ aspirin nanofiber coatings on titanium.
    Biomaterials, 2020, Volume: 257

    Topics: Aspirin; Humans; Nanofibers; Osteogenesis; Osteolysis; Titanium

2020
Melatonin suppresses Ti-particle-induced inflammatory osteolysis via activation of the Nrf2/Catalase signaling pathway.
    International immunopharmacology, 2020, Volume: 88

    Topics: Actins; Animals; Bone Marrow Cells; Catalase; Cathepsin K; Cell Differentiation; Cells, Cultured; Inflammation; Male; Melatonin; Mice, Inbred C57BL; Monocytes; NF-E2-Related Factor 2; Osteoclasts; Osteogenesis; Osteolysis; Receptors, Cell Surface; Signal Transduction; Skull; Tartrate-Resistant Acid Phosphatase; Titanium

2020
miR-34a carried by adipocyte exosomes inhibits the polarization of M1 macrophages in mouse osteolysis model.
    Journal of biomedical materials research. Part A, 2021, Volume: 109, Issue:6

    Topics: 3T3 Cells; Adipocytes; Animals; Cell Polarity; Exosomes; Genetic Therapy; Macrophages; Mice; MicroRNAs; Nanoparticles; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; RAW 264.7 Cells; Titanium; Up-Regulation

2021
Punicalagin ameliorates wear-particle-induced inflammatory bone destruction by bi-directional regulation of osteoblastic formation and osteoclastic resorption.
    Biomaterials science, 2020, Sep-21, Volume: 8, Issue:18

    Topics: Animals; Bone Resorption; Hydrolyzable Tannins; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Titanium

2020
Inhibitory effects of biochanin A on titanium particle-induced osteoclast activation and inflammatory bone resorption via NF-κB and MAPK pathways.
    Journal of cellular physiology, 2021, Volume: 236, Issue:2

    Topics: Animals; Arthroplasty, Replacement; Bone Resorption; Cell Line; Durapatite; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation, Developmental; Genistein; Humans; Inflammation; Interleukin-1alpha; Interleukin-1beta; Mice; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; Osteoporosis; Prostheses and Implants; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha

2021
Puerarin inhibits titanium particle-induced osteolysis and RANKL-induced osteoclastogenesis via suppression of the NF-κB signaling pathway.
    Journal of cellular and molecular medicine, 2020, Volume: 24, Issue:20

    Topics: Actins; Animals; Bone Resorption; Cytokines; Gene Expression Regulation; Inflammation Mediators; Isoflavones; Male; Mice; NF-kappa B; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Rats, Sprague-Dawley; RAW 264.7 Cells; Signal Transduction; Titanium

2020
A Modified Murine Calvarial Osteolysis Model Exposed to Ti Particles in Aseptic Loosening.
    BioMed research international, 2020, Volume: 2020

    Topics: Animals; Arthroplasty, Replacement; Disease Models, Animal; Mice, Inbred C57BL; Osteolysis; Prosthesis Failure; Skull; Spectrometry, X-Ray Emission; Titanium; X-Ray Diffraction; X-Ray Microtomography

2020
Tetrandrine Inhibits Titanium Particle-Induced Inflammatory Osteolysis through the Nuclear Factor-
    Mediators of inflammation, 2020, Volume: 2020

    Topics: Animals; Anti-Inflammatory Agents; Benzylisoquinolines; Bone Resorption; Calcium Signaling; Cells, Cultured; Cytokines; Humans; Mice; NF-kappa B; Osteoclasts; Osteolysis; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium

2020
STAT3/IL-6 dependent induction of inflammatory response in osteoblast and osteoclast formation in nanoscale wear particle-induced aseptic prosthesis loosening.
    Biomaterials science, 2021, Feb-21, Volume: 9, Issue:4

    Topics: Animals; Interleukin-6; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteolysis; Prosthesis Failure; Titanium

2021
Wear of hip prostheses increases serum IGFBP-1 levels in patients with aseptic loosening.
    Scientific reports, 2021, 01-12, Volume: 11, Issue:1

    Topics: Aged; Arthroplasty, Replacement, Hip; Enzyme-Linked Immunosorbent Assay; Female; Hip Prosthesis; Humans; In Vitro Techniques; Insulin-Like Growth Factor Binding Protein 1; Macrophages; Male; Osteoblasts; Osteolysis; Prosthesis Failure; Reoperation; Titanium

2021
The effect of strontium ranelate on titanium particle-induced periprosthetic osteolysis regulated by WNT/β-catenin signaling in vivo and in vitro.
    Bioscience reports, 2021, 01-29, Volume: 41, Issue:1

    Topics: 3T3 Cells; Animals; Apoptosis; beta Catenin; Culture Media, Conditioned; Female; In Vitro Techniques; Mice; Mice, Inbred C57BL; Osteoblasts; Osteolysis; Prostheses and Implants; RAW 264.7 Cells; Thiophenes; Titanium; Wnt Signaling Pathway

2021
MgO Nanoparticles Protect against Titanium Particle-Induced Osteolysis in a Mouse Model Because of Their Positive Immunomodulatory Effect.
    ACS biomaterials science & engineering, 2020, 05-11, Volume: 6, Issue:5

    Topics: Animals; Magnesium Oxide; Mice; Mice, Inbred C57BL; Nanoparticles; Osteolysis; Titanium

2020
Inhibitory effect of acetyl-11-keto-β-boswellic acid on titanium particle-induced bone loss by abrogating osteoclast formation and downregulating the ERK signaling pathway.
    International immunopharmacology, 2021, Volume: 94

    Topics: Animals; Bone Density Conservation Agents; Down-Regulation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RAW 264.7 Cells; Skull; Titanium; Triterpenes

2021
Inhibition of Sirtuin 3 prevents titanium particle-induced bone resorption and osteoclastsogenesis via suppressing ERK and JNK signaling.
    International journal of biological sciences, 2021, Volume: 17, Issue:5

    Topics: Animals; Bone Resorption; Bone-Implant Interface; Cell Differentiation; Cells, Cultured; Drug Discovery; Extracellular Signal-Regulated MAP Kinases; Interleukins; MAP Kinase Signaling System; Matrix Metalloproteinase 9; Membrane Proteins; Mice; Nerve Tissue Proteins; NFATC Transcription Factors; Osteoclasts; Osteolysis; RANK Ligand; Sirtuin 3; Titanium

2021
Inhibition of osteoclastogenesis by histone deacetylase inhibitor Quisinostat protects mice against titanium particle-induced bone loss.
    European journal of pharmacology, 2021, Aug-05, Volume: 904

    Topics: Actins; Animals; Bone Resorption; Cells, Cultured; Disease Models, Animal; Histone Deacetylase Inhibitors; Hydroxamic Acids; Macrophages; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Prostheses and Implants; Proto-Oncogene Proteins c-fos; Signal Transduction; Skull; Titanium

2021
Autophagy inhibitors 3-MA and LY294002 repress osteoclastogenesis and titanium particle-stimulated osteolysis.
    Biomaterials science, 2021, Jul-13, Volume: 9, Issue:14

    Topics: Animals; Autophagy; Chromones; Humans; Mice; Mice, Inbred C57BL; Morpholines; Osteoclasts; Osteogenesis; Osteolysis; Titanium

2021
Harmine Alleviates Titanium Particle-Induced Inflammatory Bone Destruction by Immunomodulatory Effect on the Macrophage Polarization and Subsequent Osteogenic Differentiation.
    Frontiers in immunology, 2021, Volume: 12

    Topics: Animals; Biomarkers; Bone Diseases; Cell Survival; Disease Models, Animal; Fluorescent Antibody Technique; Harmine; Immunohistochemistry; Inflammation; Macrophage Activation; Macrophages; Male; Mice; Nitric Oxide; Osteoclasts; Osteogenesis; Osteolysis; RAW 264.7 Cells; Titanium; X-Ray Microtomography

2021
Melatonin alleviates titanium nanoparticles induced osteolysis via activation of butyrate/GPR109A signaling pathway.
    Journal of nanobiotechnology, 2021, Jun-06, Volume: 19, Issue:1

    Topics: Animals; Butyrates; Fatty Acids, Volatile; Feces; Gastrointestinal Microbiome; Homeostasis; Male; Melatonin; Mice; Mice, Inbred C57BL; Mice, Knockout; Nanoparticles; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; Receptors, G-Protein-Coupled; RNA, Ribosomal, 16S; Signal Transduction; Titanium

2021
Zoledronic acid and teriparatide have a complementary therapeutic effect on aseptic loosening in a rabbit model.
    BMC musculoskeletal disorders, 2021, Jun-24, Volume: 22, Issue:1

    Topics: Animals; Male; Osteoclasts; Osteolysis; Prosthesis Failure; Rabbits; Teriparatide; Titanium; Zoledronic Acid

2021
Irisin recouples osteogenesis and osteoclastogenesis to protect wear-particle-induced osteolysis by suppressing oxidative stress and RANKL production.
    Biomaterials science, 2021, Sep-07, Volume: 9, Issue:17

    Topics: Animals; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Oxidative Stress; Titanium

2021
Notoginsenoside R1 suppresses wear particle-induced osteolysis and RANKL mediated osteoclastogenesis in vivo and in vitro.
    International immunopharmacology, 2017, Volume: 47

    Topics: Animals; Arthroplasty, Replacement; Bone Resorption; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Ginsenosides; Humans; Male; Metal Nanoparticles; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoclasts; Osteolysis; Postoperative Complications; Prosthesis Failure; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium

2017
Ten-Year Cross-Sectional Study of Mechanically Assisted Crevice Corrosion in 1352 Consecutive Patients With Metal-on-Polyethylene Total Hip Arthroplasty.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:8

    Topics: Aged; Arthroplasty, Replacement, Hip; C-Reactive Protein; Chromium; Chromium Alloys; Cobalt; Corrosion; Cross-Sectional Studies; Female; Femur Head; Hip Prosthesis; Humans; Maine; Male; Middle Aged; Osteolysis; Polyethylene; Postoperative Complications; Prevalence; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium

2017
Midterm Outcomes of Revision Total Hip Arthroplasty With the Use of a Multihole Highly-Porous Titanium Shell.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:9

    Topics: Acetabulum; Adolescent; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Biocompatible Materials; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Joint Instability; Male; Middle Aged; Osteolysis; Porosity; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium; Treatment Outcome; Young Adult

2017
Metallosis in a Dog as a Long-Term Complication Following Total Hip Arthroplasty.
    Veterinary pathology, 2017, Volume: 54, Issue:5

    Topics: Animals; Arthroplasty, Replacement, Hip; Chromium Alloys; Diagnosis, Differential; Dogs; Hip Prosthesis; Laser Capture Microdissection; Male; Metals; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Failure; Reoperation; Titanium

2017
Kaempferide Prevents Titanium Particle Induced Osteolysis by Suppressing JNK Activation during Osteoclast Formation.
    Scientific reports, 2017, 11-30, Volume: 7, Issue:1

    Topics: Animals; Anisomycin; Cell Differentiation; Cells, Cultured; Gene Expression Regulation; Immunohistochemistry; JNK Mitogen-Activated Protein Kinases; Kaempferols; MAP Kinase Signaling System; Mice; Models, Molecular; Molecular Conformation; Osteoclasts; Osteogenesis; Osteolysis; Protective Agents; RANK Ligand; Structure-Activity Relationship; Titanium; X-Ray Microtomography

2017
Comparison of an Uncemented Tapered Stem Design in Cobalt-Chrome vs Titanium at 15-Year Follow-Up.
    The Journal of arthroplasty, 2018, Volume: 33, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Chromium; Chromium Alloys; Cobalt; Female; Follow-Up Studies; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Middle Aged; Osteolysis; Pain; Prosthesis Design; Radiography; Titanium; Young Adult

2018
Strontium ranelate reduces the progression of titanium particle-induced osteolysis by increasing the ratio of osteoprotegerin to receptor activator of nuclear factor-κB ligand in vivo.
    Molecular medicine reports, 2018, Volume: 17, Issue:3

    Topics: Administration, Oral; Alloys; Animals; Biomarkers; Bone Density Conservation Agents; Bone-Implant Interface; Dose-Response Relationship, Drug; Female; Gene Expression; Mice; Mice, Inbred C57BL; Osteolysis; Osteoprotegerin; Particulate Matter; Prostheses and Implants; Prosthesis Failure; RANK Ligand; Thiophenes; Tibia; Titanium

2018
The degree of peri-implant osteolysis induced by PEEK, CoCrMo, and HXLPE wear particles: a study based on a porous Ti6Al4V implant in a rabbit model.
    Journal of orthopaedic surgery and research, 2018, Jan-31, Volume: 13, Issue:1

    Topics: Alloys; Animals; Benzophenones; Biocompatible Materials; Female; Implants, Experimental; Ketones; Knee Joint; Models, Animal; Osteolysis; Particle Size; Polyethylene; Polyethylene Glycols; Polymers; Porosity; Rabbits; Titanium; Vitallium

2018
Bulleyaconitine A prevents Ti particle-induced osteolysis via suppressing NF-κB signal pathway during osteoclastogenesis and osteoblastogenesis.
    Journal of cellular physiology, 2018, Volume: 233, Issue:9

    Topics: Aconitine; Animals; Bone Resorption; Cell Differentiation; Gene Expression Regulation; Male; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Signal Transduction; Skull; Titanium

2018
Emodin attenuates titanium particle-induced osteolysis and RANKL-mediated osteoclastogenesis through the suppression of IKK phosphorylation.
    Molecular immunology, 2018, Volume: 96

    Topics: Animals; Emodin; I-kappa B Kinase; Male; Mice; Mice, Inbred C57BL; Osteogenesis; Osteolysis; Phosphorylation; Prostheses and Implants; Protein Kinase Inhibitors; RANK Ligand; Titanium

2018
Phelligridin D-loaded oral nanotube titanium implant enhances osseointegration and prevents osteolysis in rat mandible.
    Artificial cells, nanomedicine, and biotechnology, 2018, Volume: 46, Issue:sup2

    Topics: 3T3 Cells; Administration, Oral; Animals; Benzopyrans; Cell Differentiation; Cell Proliferation; Cell Survival; Drug Carriers; Drug Liberation; Male; Mandible; Mice; Nanotubes; Osseointegration; Osteoblasts; Osteogenesis; Osteolysis; Prostheses and Implants; Rats; Rats, Sprague-Dawley; Titanium

2018
Micrometer-Sized Titanium Particles Induce Aseptic Loosening in Rabbit Knee.
    BioMed research international, 2018, Volume: 2018

    Topics: Animals; Arthroplasty, Replacement, Knee; Cell Differentiation; Femur; Knee Prosthesis; Osteoblasts; Osteoclasts; Osteolysis; Prosthesis Failure; Rabbits; Signal Transduction; Titanium

2018
Protein phosphatase 2A as a new target for downregulating osteoclastogenesis and alleviating titanium particle-induced bone resorption.
    Acta biomaterialia, 2018, Volume: 73

    Topics: Animals; Biopsy; Bone and Bones; Bone Resorption; Cell Survival; Homeostasis; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Materials Testing; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Phosphorylation; Prostheses and Implants; Protein Phosphatase 2; RANK Ligand; RNA, Small Interfering; Stress, Mechanical; Titanium; X-Ray Microtomography

2018
Small Heterodimer Partner Negatively Regulates TLR4 Signaling Pathway of Titanium Particles-Induced Osteolysis in Mice.
    Journal of biomedical nanotechnology, 2018, Mar-01, Volume: 14, Issue:3

    Topics: Animals; Macrophages; Mice; Osteoclasts; Osteolysis; RAW 264.7 Cells; Signal Transduction; Titanium; Toll-Like Receptor 4; Tumor Necrosis Factor-alpha

2018
Hip resurfacing with a highly cross-linked polyethylene acetabular liner and a titanium nitride-coated femoral component.
    Hip international : the journal of clinical and experimental research on hip pathology and therapy, 2018, Volume: 28, Issue:4

    Topics: Acetabulum; Adult; Aged; Arthroplasty, Replacement, Hip; Female; Femur; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Design; Radiography; Titanium; Tomography, X-Ray Computed; Young Adult

2018
Gö6983 attenuates titanium particle-induced osteolysis and RANKL mediated osteoclastogenesis through the suppression of NFκB/JNK/p38 pathways.
    Biochemical and biophysical research communications, 2018, 09-03, Volume: 503, Issue:1

    Topics: Animals; Cell Differentiation; Cells, Cultured; Disease Models, Animal; Down-Regulation; Durapatite; Humans; In Vitro Techniques; Indoles; Male; Maleimides; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; p38 Mitogen-Activated Protein Kinases; Prosthesis Failure; Protein Kinase Inhibitors; RANK Ligand; Skull; Titanium

2018
Pulsed electromagnetic fields and platelet rich plasma alone and combined for the treatment of wear-mediated periprosthetic osteolysis: An in vivo study.
    Acta biomaterialia, 2018, 09-01, Volume: 77

    Topics: Alloys; Animals; Biomechanical Phenomena; Bone and Bones; Electromagnetic Fields; Hardness; Joint Prosthesis; Macrophages; Male; Osseointegration; Osteoclasts; Osteogenesis; Osteolysis; Platelet-Rich Plasma; Polyethylene; Polyethylenes; Rats; Rats, Inbred F344; Titanium; X-Ray Microtomography

2018
Titanium particle‑mediated osteoclastogenesis may be attenuated via bidirectional ephrin‑B2/eph‑B4 signaling in vitro.
    International journal of molecular medicine, 2018, Volume: 42, Issue:4

    Topics: Animals; Antigens, Differentiation; Cell Line; Ephrin-B2; Female; Mice; Osteoclasts; Osteolysis; Signal Transduction; Titanium

2018
Arctigenin inhibits RANKL-induced osteoclastogenesis and hydroxyapatite resorption in vitro and prevents titanium particle-induced bone loss in vivo.
    Journal of cellular biochemistry, 2019, Volume: 120, Issue:4

    Topics: Animals; Arthroplasty, Replacement; Bone Resorption; Cell Proliferation; Disease Models, Animal; Durapatite; Furans; Gene Expression Regulation, Developmental; Humans; Lignans; Mice; Osteoclasts; Osteogenesis; Osteolysis; Prostheses and Implants; RANK Ligand; Titanium; Transcription Factor RelA

2019
Antiresorptive Agents are More Effective in Preventing Titanium Particle-Induced Calvarial Osteolysis in Ovariectomized Mice Than Anabolic Agents in Short-Term Administration.
    Artificial organs, 2018, Volume: 42, Issue:9

    Topics: Anabolic Agents; Animals; Bone Density Conservation Agents; Female; Mice; Osteolysis; Ovariectomy; Skull; Titanium

2018
PEEK versus metal cages in posterior lumbar interbody fusion: a clinical and radiological comparative study.
    Musculoskeletal surgery, 2019, Volume: 103, Issue:3

    Topics: Activities of Daily Living; Adult; Benzophenones; Biocompatible Materials; Female; Humans; Ketones; Low Back Pain; Lumbar Vertebrae; Male; Middle Aged; Osteolysis; Pain Measurement; Polyethylene Glycols; Polymers; Retrospective Studies; Spinal Fusion; Tantalum; Titanium

2019
Mechanism and Prevention of Titanium Particle-Induced Inflammation and Osteolysis.
    Frontiers in immunology, 2018, Volume: 9

    Topics: Animals; Antibodies, Neutralizing; Cells, Cultured; Cytokines; Dental Implants; Disease Models, Animal; Female; Humans; Macrophages; Mice; Mice, Inbred C57BL; Osteogenesis; Osteolysis; Peri-Implantitis; Primary Cell Culture; Skull; Titanium; X-Ray Microtomography

2018
Metallic wear debris collected from patients induces apoptosis in rat primary osteoblasts via reactive oxygen species‑mediated mitochondrial dysfunction and endoplasmic reticulum stress.
    Molecular medicine reports, 2019, Volume: 19, Issue:3

    Topics: Animals; Apoptosis; Arthroplasty, Replacement, Hip; Endoplasmic Reticulum Stress; Hip Joint; Humans; Metals; Mitochondria; Osteoblasts; Osteolysis; Particle Size; Primary Cell Culture; Prostheses and Implants; Prosthesis Failure; Rats; Reactive Oxygen Species; Titanium

2019
Vaccarin prevents titanium particle-induced osteolysis and inhibits RANKL-induced osteoclastogenesis by blocking NF-κB and MAPK signaling pathways.
    Journal of cellular physiology, 2019, Volume: 234, Issue:8

    Topics: Animals; Biomarkers; Bone Resorption; Cell Differentiation; Disease Models, Animal; Durapatite; Flavonoids; Gene Expression Regulation; Glycosides; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proto-Oncogene Proteins c-fos; RANK Ligand; RAW 264.7 Cells; Skull; Titanium

2019
Osteocytes respond to particles of clinically-relevant conventional and cross-linked polyethylene and metal alloys by up-regulation of resorptive and inflammatory pathways.
    Acta biomaterialia, 2019, 03-15, Volume: 87

    Topics: Alloys; Antigens, Differentiation; Bone-Implant Interface; Humans; Osteocytes; Osteolysis; Polyethylenes; Titanium; Up-Regulation

2019
Screw Track Osteolysis in the Cementless Total Knee Replacement Design.
    The Journal of arthroplasty, 2019, Volume: 34, Issue:5

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Biocompatible Materials; Bone Cements; Bone Screws; Cementation; Equipment Failure Analysis; Female; Humans; Knee Prosthesis; Male; Middle Aged; Osteoarthritis, Knee; Osteolysis; Prosthesis Design; Prosthesis Failure; Tibia; Titanium

2019
Anti-inflammatory drug-eluting implant model system to prevent wear particle-induced periprosthetic osteolysis.
    International journal of nanomedicine, 2019, Volume: 14

    Topics: Animals; Anti-Inflammatory Agents; Cell Survival; Dexamethasone; Drug Liberation; Joint Prosthesis; Macrophages; Mice; Nanoparticles; Nitric Oxide; Osteolysis; Prosthesis Failure; RAW 264.7 Cells; Spectroscopy, Fourier Transform Infrared; Static Electricity; Temperature; Titanium; Tumor Necrosis Factor-alpha

2019
Rhoifolin ameliorates titanium particle-stimulated osteolysis and attenuates osteoclastogenesis via RANKL-induced NF-κB and MAPK pathways.
    Journal of cellular physiology, 2019, Volume: 234, Issue:10

    Topics: Animals; Cells, Cultured; Disaccharides; Flavonoids; Gene Expression; Glycosides; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; Osteogenesis; Osteolysis; Particle Size; Prosthesis Failure; RANK Ligand; Skull; Titanium; X-Ray Microtomography

2019
MiR-377 inhibits wear particle-induced osteolysis via targeting RANKL.
    Cell biology international, 2019, Volume: 43, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Cell Differentiation; Cytokines; Down-Regulation; Female; Humans; Interleukin-6; Macrophages; Male; MicroRNAs; Middle Aged; Osteoclasts; Osteolysis; RANK Ligand; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha

2019
NOD2 negatively regulated titanium particle-induced osteolysis in mice.
    Biomaterials science, 2019, Jul-01, Volume: 7, Issue:7

    Topics: Aminoquinolines; Animals; Female; Humans; Inflammation Mediators; Macrophage Activation; Male; Mice; Middle Aged; NF-kappa B; Nod2 Signaling Adaptor Protein; Osteolysis; Prosthesis Failure; RAW 264.7 Cells; Signal Transduction; Sulfones; Titanium

2019
Ghrelin Fights Against Titanium Particle-Induced Inflammatory Osteolysis Through Activation of β-Catenin Signaling Pathway.
    Inflammation, 2019, Volume: 42, Issue:5

    Topics: 3T3 Cells; Animals; beta Catenin; Ghrelin; Inflammation; Mice; Osteolysis; Particle Size; Particulate Matter; Protective Agents; Signal Transduction; Titanium

2019
Pentamidine Inhibits Titanium Particle-Induced Osteolysis
    Tissue engineering and regenerative medicine, 2019, Volume: 16, Issue:3

    Topics: Animals; Cell Differentiation; Cell Survival; Disease Models, Animal; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Pentamidine; Prostheses and Implants; RANK Ligand; Skull; Titanium; X-Ray Microtomography

2019
Cepharanthine ameliorates titanium particle-induced osteolysis by inhibiting osteoclastogenesis and modulating OPG/RANKL ratio in a murine model.
    Biochemical and biophysical research communications, 2019, 09-24, Volume: 517, Issue:3

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Benzylisoquinolines; Bone-Anchored Prosthesis; Bone-Implant Interface; Cathepsin D; Disease Models, Animal; Gene Expression Regulation; Male; Mice; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Prosthesis Failure; RANK Ligand; Skull; Tartrate-Resistant Acid Phosphatase; Titanium

2019
Titanium particle-challenged osteoblasts promote osteoclastogenesis and osteolysis in a murine model of periprosthestic osteolysis.
    Acta biomaterialia, 2013, Volume: 9, Issue:7

    Topics: Animals; Biocompatible Materials; Cell Differentiation; Dose-Response Relationship, Drug; Equipment Failure Analysis; Humans; Knee Prosthesis; Male; Materials Testing; Mice; Mice, Inbred BALB C; Osteoblasts; Osteoclasts; Osteolysis; Titanium

2013
High survivorship with a titanium-encased alumina ceramic bearing for total hip arthroplasty.
    Clinical orthopaedics and related research, 2014, Volume: 472, Issue:2

    Topics: Adult; Aluminum Oxide; Arthroplasty, Replacement, Hip; Female; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Male; Middle Aged; Noise; Osteolysis; Prosthesis Design; Prosthesis Failure; Stress, Mechanical; Time Factors; Titanium; Treatment Outcome; United States

2014
Characterization of wear debris in total elbow arthroplasty.
    Journal of shoulder and elbow surgery, 2013, Volume: 22, Issue:7

    Topics: Aged; Arthroplasty, Replacement, Elbow; Artifacts; Bone Cements; Chromium Alloys; Equipment Failure Analysis; Female; Humans; Joint Capsule; Joint Instability; Male; Microscopy, Electron, Scanning; Middle Aged; Osteolysis; Particle Size; Polyethylenes; Preoperative Care; Prosthesis Failure; Reoperation; Sampling Studies; Sensitivity and Specificity; Titanium

2013
rna interference targeting p110β reduces tumor necrosis factor-alpha production in cellular response to wear particles in vitro and osteolysis in vivo.
    Inflammation, 2013, Volume: 36, Issue:5

    Topics: Animals; Arthroplasty, Replacement; Cell Line; Ceramics; Class I Phosphatidylinositol 3-Kinases; Enzyme Activation; Inflammation; Joint Prosthesis; Lentivirus; Macrophages; Male; Mice; Mice, Inbred C57BL; Nanoparticles; Osteoclasts; Osteolysis; Prosthesis Failure; Proto-Oncogene Proteins c-akt; RNA Interference; RNA, Messenger; RNA, Small Interfering; Titanium; Tumor Necrosis Factor-alpha

2013
[Experimental study on small interfering RNA silencing expression of tumor necrosis factor alpha and inhibiting osteolysis].
    Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery, 2013, Volume: 27, Issue:8

    Topics: Adenoviridae; Animals; Disease Models, Animal; Female; Gene Silencing; Genetic Therapy; HEK293 Cells; Humans; Joint Prosthesis; Mice; Mice, Inbred BALB C; Osteolysis; Prosthesis Failure; Random Allocation; RNA, Small Interfering; Titanium; Transfection; Tumor Necrosis Factor-alpha

2013
Titanium and zirconia particle-induced pro-inflammatory gene expression in cultured macrophages and osteolysis, inflammatory hyperalgesia and edema in vivo.
    Life sciences, 2014, Mar-03, Volume: 97, Issue:2

    Topics: Animals; Cells, Cultured; Cytokines; Edema; Gene Expression Regulation; Hyperalgesia; Inflammation; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteolysis; RNA, Messenger; Skull; Titanium; Toll-Like Receptors; Zirconium

2014
Metal metaphyseal sleeves in revision total knee replacement.
    The bone & joint journal, 2013, Volume: 95-B, Issue:12

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Female; Follow-Up Studies; Humans; Knee Joint; Knee Prosthesis; Male; Middle Aged; Osseointegration; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Severity of Illness Index; Tibia; Titanium; Treatment Outcome

2013
Particle-induced osteolysis is not accompanied by systemic remodeling but is reflected by systemic bone biomarkers.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2014, Volume: 32, Issue:7

    Topics: Animals; Biomarkers; Bone and Bones; Bone Remodeling; Bone Resorption; Femur; Gene Expression Regulation; Humerus; Lumbar Vertebrae; Male; Osteolysis; Prostheses and Implants; Prosthesis Failure; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tibia; Titanium; X-Ray Microtomography

2014
The effect of enoxacin on osteoclastogenesis and reduction of titanium particle-induced osteolysis via suppression of JNK signaling pathway.
    Biomaterials, 2014, Volume: 35, Issue:22

    Topics: Animals; Anti-Infective Agents; Cell Line; Enoxacin; Gene Expression Regulation; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Prostheses and Implants; Titanium

2014
Geraniin suppresses RANKL-induced osteoclastogenesis in vitro and ameliorates wear particle-induced osteolysis in mouse model.
    Experimental cell research, 2015, Jan-01, Volume: 330, Issue:1

    Topics: Actins; Animals; Glucosides; Hydrolyzable Tannins; Macrophages; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; Proto-Oncogene Proteins c-fos; RANK Ligand; Skull; Titanium

2015
Wear particles and ions from cemented and uncemented titanium-based hip prostheses-a histological and chemical analysis of retrieval material.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2015, Volume: 103, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Alloys; Bone Cements; Device Removal; Female; Foreign-Body Reaction; Friction; Hip Joint; Hip Prosthesis; Histiocytes; Humans; Inflammation; Joint Capsule; Macrophages; Male; Middle Aged; Necrosis; Neutrophils; Osteolysis; Polyethylene; Prosthesis Failure; Titanium; Zirconium

2015
Strontium ranelate inhibits titanium-particle-induced osteolysis by restraining inflammatory osteoclastogenesis in vivo.
    Acta biomaterialia, 2014, Volume: 10, Issue:11

    Topics: Acid Phosphatase; Animals; Inflammation; Interleukin-1beta; Isoenzymes; Male; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; RANK Ligand; RNA, Messenger; Skull; Staining and Labeling; Tartrate-Resistant Acid Phosphatase; Thiophenes; Titanium; Tumor Necrosis Factor-alpha; X-Ray Microtomography

2014
The prevention of titanium-particle-induced osteolysis by OA-14 through the suppression of the p38 signaling pathway and inhibition of osteoclastogenesis.
    Biomaterials, 2014, Volume: 35, Issue:32

    Topics: Acid Phosphatase; Actins; Animals; Benzamides; Bone Resorption; Cell Survival; Cells, Cultured; Indoles; Isoenzymes; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; RANK Ligand; Tartrate-Resistant Acid Phosphatase; Titanium

2014
Porous titanium particles for acetabular reconstruction in total hip replacement show extensive bony armoring after 15 weeks. A loaded in vivo study in 10 goats.
    Acta orthopaedica, 2014, Volume: 85, Issue:6

    Topics: Acetabulum; Animals; Arthroplasty, Replacement, Hip; Bone Transplantation; Calcium Phosphates; Cementation; Coated Materials, Biocompatible; Disease Models, Animal; Goats; Hip Prosthesis; Materials Testing; Osteolysis; Plastic Surgery Procedures; Polyethylene; Porosity; Prosthesis Failure; Titanium

2014
Inhibitory effects of triptolide on titanium particle-induced osteolysis and receptor activator of nuclear factor-κB ligand-mediated osteoclast differentiation.
    International orthopaedics, 2015, Volume: 39, Issue:1

    Topics: Acid Phosphatase; Animals; Blotting, Western; Cell Differentiation; Cell Survival; Diterpenes; Epoxy Compounds; Isoenzymes; Macrophages; Male; Mice; Mice, Inbred ICR; Osteoclasts; Osteolysis; Phenanthrenes; Receptor Activator of Nuclear Factor-kappa B; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Tartrate-Resistant Acid Phosphatase; Titanium

2015
Triptolide inhibits osteoclast formation, bone resorption, RANKL-mediated NF-қB activation and titanium particle-induced osteolysis in a mouse model.
    Molecular and cellular endocrinology, 2015, Jan-05, Volume: 399

    Topics: Animals; Antineoplastic Agents, Alkylating; Cell Line; Diterpenes; Epoxy Compounds; Mice; Osteoclasts; Osteolysis; Phenanthrenes; RANK Ligand; Titanium; Transcription Factor RelA

2015
Myricetin prevents titanium particle-induced osteolysis in vivo and inhibits RANKL-induced osteoclastogenesis in vitro.
    Biochemical pharmacology, 2015, Jan-01, Volume: 93, Issue:1

    Topics: Animals; Cells, Cultured; Dose-Response Relationship, Drug; Flavonoids; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Particle Size; Random Allocation; RANK Ligand; Titanium

2015
The inhibition of RANKL-induced osteoclastogenesis through the suppression of p38 signaling pathway by naringenin and attenuation of titanium-particle-induced osteolysis.
    International journal of molecular sciences, 2014, Nov-28, Volume: 15, Issue:12

    Topics: Actins; Animals; Anisomycin; Bone Resorption; Cell Death; Cell Differentiation; Extracellular Signal-Regulated MAP Kinases; Flavanones; Gene Expression Regulation; Humans; JNK Mitogen-Activated Protein Kinases; MAP Kinase Signaling System; Mice, Inbred C57BL; Models, Biological; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteogenesis; Osteolysis; p38 Mitogen-Activated Protein Kinases; RANK Ligand; Titanium

2014
Inhibitory effects of ursolic acid on osteoclastogenesis and titanium particle-induced osteolysis are mediated primarily via suppression of NF-κB signaling.
    Biochimie, 2015, Volume: 111

    Topics: Animals; Male; MAP Kinase Kinase 4; Mice; NF-kappa B; NFATC Transcription Factors; Osteoclasts; Osteolysis; RANK Ligand; Signal Transduction; Titanium; Triterpenes; Ursolic Acid

2015
Protective effect of p38 MAPK inhibitor on wear debris-induced inflammatory osteolysis through downregulating RANK/RANKL in a mouse model.
    Genetics and molecular research : GMR, 2015, Jan-15, Volume: 14, Issue:1

    Topics: Acid Phosphatase; Animals; Bone and Bones; Colonic Pouches; Disease Models, Animal; Down-Regulation; Female; Immunohistochemistry; Inflammation; Isoenzymes; Mice, Inbred BALB C; Osteolysis; p38 Mitogen-Activated Protein Kinases; Prostheses and Implants; Protective Agents; Protein Kinase Inhibitors; RANK Ligand; Real-Time Polymerase Chain Reaction; Receptor Activator of Nuclear Factor-kappa B; Tartrate-Resistant Acid Phosphatase; Titanium

2015
Tumor necrosis factor-like weak inducer of apoptosis regulates particle-induced inflammatory osteolysis via the p38 mitogen-activated protein kinase signaling pathway.
    Molecular medicine reports, 2015, Volume: 12, Issue:1

    Topics: Animals; Apoptosis; Arthroplasty, Replacement, Hip; Chemokine CCL2; Cytokine TWEAK; Gene Expression Regulation; Humans; Inflammation; Interleukin-6; Macrophages; MAP Kinase Signaling System; Mice; Osteolysis; p38 Mitogen-Activated Protein Kinases; Titanium; Tumor Necrosis Factors

2015
Icariin protects against titanium particle-induced osteolysis and inflammatory response in a mouse calvarial model.
    Biomaterials, 2015, Volume: 60

    Topics: Animals; Disease Models, Animal; Drugs, Chinese Herbal; Epimedium; Flavonoids; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice; Mice, Inbred C57BL; Osteolysis; Skull; Titanium; Tumor Necrosis Factor-alpha

2015
Primary ceramic-on-ceramic total hip arthroplasty using a 32-mm ceramic head with a titanium-alloy sleeve.
    Clinical orthopaedics and related research, 2015, Volume: 473, Issue:12

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Disease-Free Survival; Female; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Male; Metal Ceramic Alloys; Middle Aged; Noise; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Republic of Korea; Retrospective Studies; Risk Factors; Surveys and Questionnaires; Time Factors; Titanium; Treatment Outcome; Young Adult

2015
Polycan suppresses osteoclast differentiation and titanium particle-induced osteolysis in mice.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2016, Volume: 104, Issue:6

    Topics: Animals; Ascomycota; Cell Differentiation; Cytokines; Fungal Polysaccharides; Mice; Mice, Inbred ICR; Osteoclasts; Osteolysis; Titanium

2016
Lycorine suppresses RANKL-induced osteoclastogenesis in vitro and prevents ovariectomy-induced osteoporosis and titanium particle-induced osteolysis in vivo.
    Scientific reports, 2015, Aug-04, Volume: 5

    Topics: Amaryllidaceae Alkaloids; Animals; Bone Density Conservation Agents; Bone Marrow; Cell Differentiation; Cell Survival; Disease Models, Animal; Female; Gene Expression Regulation; Macrophages; Male; MAP Kinase Kinase 4; MAP Kinase Kinase 7; Mice; Mice, Inbred C57BL; Mice, Transgenic; Osteoclasts; Osteogenesis; Osteolysis; Osteoporosis; Ovariectomy; Phenanthridines; Primary Cell Culture; RANK Ligand; Signal Transduction; Titanium

2015
Pharmaceutical inhibition of glycogen synthetase kinase 3 beta suppresses wear debris-induced osteolysis.
    Biomaterials, 2015, Volume: 69

    Topics: Animals; Female; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Lithium Chloride; Mice; Mice, Inbred C57BL; Osteolysis; Prostheses and Implants; Protein Kinase Inhibitors; Skull; Titanium

2015
Diagnosis and Management of Adverse Local Tissue Reactions Secondary to Corrosion at the Head-Neck Junction in Patients With Metal on Polyethylene Bearings.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:1

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Blood Sedimentation; Body Mass Index; Ceramics; Chromium; Cobalt; Corrosion; Disease Management; Female; Foreign-Body Reaction; Hip Prosthesis; Humans; Male; Metals; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium

2016
Inhibition of RANKL-induced osteoclastogenesis through the suppression of the ERK signaling pathway by astragaloside IV and attenuation of titanium-particle-induced osteolysis.
    International journal of molecular medicine, 2015, Volume: 36, Issue:5

    Topics: Animals; Cell Line; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Ligands; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Saponins; Titanium; Triterpenes

2015
ER Stress Mediates TiAl6V4 Particle-Induced Peri-Implant Osteolysis by Promoting RANKL Expression in Fibroblasts.
    PloS one, 2015, Volume: 10, Issue:9

    Topics: Alloys; Animals; Biomarkers; Bone-Implant Interface; Cells, Cultured; Endoplasmic Reticulum Chaperone BiP; Endoplasmic Reticulum Stress; Female; Fibroblasts; Gene Expression Regulation; Humans; Male; Mice; Osteolysis; RANK Ligand; Titanium

2015
Expression of XBP1s in fibroblasts is critical for TiAl
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2017, Volume: 35, Issue:4

    Topics: Aged; Alloys; Animals; Arthroplasty, Replacement, Hip; Female; Fibroblasts; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Osteoclasts; Osteolysis; Prosthesis Failure; RANK Ligand; RNA, Small Interfering; Synovial Membrane; Titanium; X-Box Binding Protein 1; X-Ray Microtomography

2017
Nanoscale surface modification by anodic oxidation increased bone ingrowth and reduced fibrous tissue in the porous coating of titanium-alloy femoral hip arthroplasty implants.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2017, Volume: 105, Issue:2

    Topics: Alloys; Animals; Arthroplasty, Replacement, Hip; Dogs; Hip Prosthesis; Male; Osteolysis; Oxidation-Reduction; Surface Properties; Titanium

2017
Inhibition of titanium-particle-induced inflammatory osteolysis after local administration of dopamine and suppression of osteoclastogenesis via D2-like receptor signaling pathway.
    Biomaterials, 2016, Volume: 80

    Topics: Animals; Cells, Cultured; Dopamine; Inflammation; Interleukin-1beta; Interleukin-6; Male; Mice, Inbred C57BL; Osteoclasts; Osteolysis; RANK Ligand; Receptors, Dopamine D2; Signal Transduction; Skull; Titanium; Tumor Necrosis Factor-alpha; X-Ray Microtomography

2016
Dihydroartemisinin prevents breast cancer-induced osteolysis via inhibiting both breast caner cells and osteoclasts.
    Scientific reports, 2016, Jan-08, Volume: 6

    Topics: Actins; Animals; Artemisinins; Bone Density; Breast Neoplasms; Cell Differentiation; Cell Line, Tumor; Cell Movement; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteolysis; Proto-Oncogene Proteins c-akt; Signal Transduction; src-Family Kinases; Titanium; Xenograft Model Antitumor Assays

2016
Biomechanical Analysis of Implanted Clavicle Hook Plates With Different Implant Depths and Materials in the Acromioclavicular Joint: A Finite Element Analysis Study.
    Artificial organs, 2016, Volume: 40, Issue:11

    Topics: Acromioclavicular Joint; Alloys; Biomechanical Phenomena; Bone Plates; Clavicle; Computer Simulation; Finite Element Analysis; Fracture Fixation, Internal; Humans; Joint Dislocations; Osteolysis; Periprosthetic Fractures; Postoperative Complications; Stainless Steel; Titanium; Treatment Outcome

2016
Progranulin suppresses titanium particle induced inflammatory osteolysis by targeting TNFα signaling.
    Scientific reports, 2016, Feb-11, Volume: 6

    Topics: Animals; Animals, Newborn; Cell Differentiation; Cell Line; Gene Expression; Granulins; I-kappa B Kinase; Inflammation; Intercellular Signaling Peptides and Proteins; Macrophages; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Particle Size; Phosphorylation; Progranulins; RANK Ligand; Signal Transduction; Skull; Titanium; Transcription Factor RelA; Tumor Necrosis Factor-alpha

2016
Resveratrol Protects against Titanium Particle-Induced Aseptic Loosening Through Reduction of Oxidative Stress and Inactivation of NF-κB.
    Inflammation, 2016, Volume: 39, Issue:2

    Topics: Animals; Antioxidants; Catalase; Cell Line; Female; Glutathione Peroxidase; Glutathione Reductase; Lipid Peroxidation; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; NADH, NADPH Oxidoreductases; NADPH Oxidase 1; NADPH Oxidase 2; NADPH Oxidases; NF-kappa B; Nitric Oxide; Nitric Oxide Synthase Type II; Osteolysis; Oxidative Stress; Prostheses and Implants; RAW 264.7 Cells; Reactive Oxygen Species; Resveratrol; Stilbenes; Superoxide Dismutase; Titanium; Tumor Necrosis Factor-alpha

2016
Particle-Induced Osteolysis Is Mediated by TIRAP/Mal in Vitro and in Vivo: Dependence on Adherent Pathogen-Associated Molecular Patterns.
    The Journal of bone and joint surgery. American volume, 2016, Feb-17, Volume: 98, Issue:4

    Topics: Animals; Biomarkers; Cytokines; Female; Joint Prosthesis; Lipopolysaccharides; Macrophages; Membrane Glycoproteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Osteolysis; Pathogen-Associated Molecular Pattern Molecules; Prosthesis Failure; Random Allocation; Receptors, Interleukin-1; Titanium

2016
Adenovirus-mediated siRNA targeting CXCR2 attenuates titanium particle-induced osteolysis by suppressing osteoclast formation.
    Medical science monitor : international medical journal of experimental and clinical research, 2016, Mar-04, Volume: 22

    Topics: Adenoviridae; Animals; Bone Marrow Cells; Female; Macrophages; Mice; Mice, Inbred BALB C; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; RANK Ligand; RAW 264.7 Cells; Receptors, Interleukin-8B; RNA, Small Interfering; Signal Transduction; Skull; Titanium; Up-Regulation

2016
Autophagy mediated TiAl₆V₄ particle-induced peri-implant osteolysis by promoting expression of TNF-α.
    Biochemical and biophysical research communications, 2016, Apr-22, Volume: 473, Issue:1

    Topics: Adenine; Aged; Aged, 80 and over; Alloys; Animals; Autophagy; Disease Models, Animal; Female; Humans; Macrophages; Macrophages, Peritoneal; Male; Mice; Mice, Inbred C57BL; Middle Aged; Osteolysis; p38 Mitogen-Activated Protein Kinases; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha; Up-Regulation; X-Ray Microtomography

2016
Highly Cross-linked Polyethylene Provides Decreased Osteolysis and Reoperation at Minimum 10-Year Follow-Up.
    The Journal of arthroplasty, 2016, Volume: 31, Issue:9

    Topics: Acetabulum; Adult; Aged; Arthroplasty, Replacement, Hip; Bone Screws; Female; Follow-Up Studies; Hip Prosthesis; Humans; Incidence; Male; Middle Aged; North Carolina; Osteolysis; Polyethylene; Prosthesis Failure; Reoperation; Titanium

2016
Icariin attenuates titanium-particle inhibition of bone formation by activating the Wnt/β-catenin signaling pathway in vivo and in vitro.
    Scientific reports, 2016, Mar-31, Volume: 6

    Topics: Administration, Topical; Animals; beta Catenin; Bone-Implant Interface; Bridged Bicyclo Compounds, Heterocyclic; Cell Differentiation; Drugs, Chinese Herbal; Female; Flavonoids; Gene Expression; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Osteoblasts; Osteoclasts; Osteogenesis; Osteolysis; Primary Cell Culture; Pyrimidinones; Signal Transduction; Skull; Titanium

2016
Backside Wear Analysis of Retrieved Acetabular Liners with a Press-Fit Locking Mechanism in Comparison to Wear Simulation In Vitro.
    BioMed research international, 2016, Volume: 2016

    Topics: Acetabulum; Alloys; Internal Fixators; Materials Testing; Motion; Osteolysis; Polyethylenes; Prosthesis Failure; Stress, Mechanical; Surface Properties; Titanium

2016
Scutellarin inhibits RANKL-mediated osteoclastogenesis and titanium particle-induced osteolysis via suppression of NF-κB and MAPK signaling pathway.
    International immunopharmacology, 2016, Volume: 40

    Topics: Animals; Anti-Inflammatory Agents; Apigenin; Bone Resorption; Drugs, Chinese Herbal; Extracellular Signal-Regulated MAP Kinases; Glucuronates; Humans; Macrophages; Male; Mice; Mice, Inbred C57BL; Microspheres; NF-kappa B; Osteoclasts; Osteolysis; Prosthesis Failure; RANK Ligand; RAW 264.7 Cells; Signal Transduction; Titanium

2016
Lentivirus-mediated short hairpin RNA interference targeting TNF-alpha in macrophages inhibits particle-induced inflammation and osteolysis in vitro and in vivo.
    BMC musculoskeletal disorders, 2016, 10-18, Volume: 17, Issue:1

    Topics: Animals; Ceramics; Disease Models, Animal; Gene Knockdown Techniques; Genetic Vectors; Humans; Inflammation; Joint Prosthesis; Lentivirus; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteolysis; Particle Size; Prosthesis Failure; RAW 264.7 Cells; Real-Time Polymerase Chain Reaction; RNA Interference; RNA, Messenger; RNA, Small Interfering; RNAi Therapeutics; Skull; Titanium; Tumor Necrosis Factor-alpha

2016
Platelet-derived growth factor-BB attenuates titanium-particle-induced osteolysis in vivo.
    Growth factors (Chur, Switzerland), 2016, Volume: 34, Issue:5-6

    Topics: Animals; Becaplermin; Bone-Implant Interface; Interleukin-1beta; Interleukin-6; Mice; Mice, Inbred C57BL; Osteolysis; Platelet Endothelial Cell Adhesion Molecule-1; Proto-Oncogene Proteins c-sis; Titanium; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2016
Theaflavin-3,3'-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway.
    Acta biomaterialia, 2017, 01-15, Volume: 48

    Topics: Animals; Biflavonoids; Bone Resorption; Catechin; Gene Expression Regulation; Male; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; RANK Ligand; RAW 264.7 Cells; Skull; Titanium

2017
SIRT1 protects osteoblasts against particle-induced inflammatory responses and apoptosis in aseptic prosthesis loosening.
    Acta biomaterialia, 2017, Volume: 49

    Topics: Alloys; Animals; Apoptosis; Cell Line; Cytoprotection; Disease Models, Animal; Down-Regulation; Fluorescent Antibody Technique; Inflammation; Mice, Inbred C57BL; NF-kappa B; Osteoblasts; Osteolysis; Prosthesis Failure; Signal Transduction; Sirtuin 1; Titanium; Tumor Suppressor Protein p53

2017
Incidence of Ceramic Liner Malseating After Ceramic-on-Ceramic Total Hip Arthroplasty Associated With Osteolysis: A 5- to 15-Year Follow-Up Study.
    The Journal of arthroplasty, 2017, Volume: 32, Issue:5

    Topics: Acetabulum; Adult; Aged; Alloys; Arthroplasty, Replacement, Hip; Ceramics; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Incidence; Kaplan-Meier Estimate; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Risk Factors; Titanium; Treatment Outcome

2017
Scaling of titanium implants entrains inflammation-induced osteolysis.
    Scientific reports, 2017, 01-06, Volume: 7

    Topics: Animals; Cells, Cultured; Dental Implants; Dental Scaling; Female; Mice, Inbred C57BL; Osteogenesis; Osteolysis; Peri-Implantitis; Titanium

2017
Suppression of osteogenic activity by regulation of WNT and BMP signaling during titanium particle induced osteolysis.
    Journal of biomedical materials research. Part A, 2017, Volume: 105, Issue:3

    Topics: Animals; Bone Morphogenetic Proteins; Cell Line; Male; Mice; Mice, Inbred ICR; Osteoclasts; Osteogenesis; Osteolysis; Titanium; Wnt Signaling Pathway

2017
Melatonin attenuates titanium particle-induced osteolysis via activation of Wnt/β-catenin signaling pathway.
    Acta biomaterialia, 2017, 03-15, Volume: 51

    Topics: Animals; beta Catenin; Bone Regeneration; Cell Differentiation; Disease Models, Animal; Intercellular Signaling Peptides and Proteins; Male; Melatonin; Mesenchymal Stem Cells; Mice, Inbred C57BL; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; RANK Ligand; Skull; Titanium; Wnt Signaling Pathway

2017
Rifampin suppresses osteoclastogenesis and titanium particle-induced osteolysis via modulating RANKL signaling pathways.
    Biochemical and biophysical research communications, 2017, 02-26, Volume: 484, Issue:1

    Topics: Animals; Cell Differentiation; Dose-Response Relationship, Drug; Gene Expression; Mice; NF-kappa B; Osteogenesis; Osteolysis; p38 Mitogen-Activated Protein Kinases; RANK Ligand; Rifampin; Signal Transduction; Titanium; X-Ray Microtomography

2017
11R-VIVIT Peptide Inhibits Calvaria Osteolysis Induced by Experimental Design.
    The Journal of craniofacial surgery, 2017, Volume: 28, Issue:2

    Topics: Animals; Drug Administration Schedule; Injections, Intraperitoneal; Male; Mice, Inbred C57BL; Oligopeptides; Osteoclasts; Osteogenesis; Osteolysis; Prostheses and Implants; Prosthesis Failure; Research Design; Skull; Titanium

2017
Osteolysis in third-generation alumina ceramic-on-ceramic hip bearings with severe impingement and titanium metallosis.
    The Journal of arthroplasty, 2008, Volume: 23, Issue:8

    Topics: Adult; Aluminum Oxide; Arthroplasty, Replacement, Hip; Ceramics; Female; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Range of Motion, Articular; Titanium

2008
The results of the titanium-coated RM acetabular component at 20 years: a long-term follow-up of an uncemented primary total hip replacement.
    The Journal of bone and joint surgery. British volume, 2008, Volume: 90, Issue:10

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Equipment Failure Analysis; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prospective Studies; Prosthesis Design; Prosthesis-Related Infections; Range of Motion, Articular; Retreatment; Titanium; Treatment Outcome

2008
Primary total hip arthroplasty in severe developmental dysplasia of the hip. Ten-year results using a cementless modular stem.
    The Journal of arthroplasty, 2009, Volume: 24, Issue:1

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Bone Diseases, Developmental; Bone Transplantation; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Longitudinal Studies; Male; Middle Aged; Osteolysis; Outcome Assessment, Health Care; Radiography; Risk Factors; Titanium

2009
Wear is reduced in THA performed with highly cross-linked polyethylene.
    Clinical orthopaedics and related research, 2009, Volume: 467, Issue:7

    Topics: Adult; Arthroplasty, Replacement, Hip; Chromium Alloys; Cross-Linking Reagents; Female; Follow-Up Studies; Hip Prosthesis; Humans; Incidence; Male; Middle Aged; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Failure; Titanium

2009
Skull bone flap fixation--comparative experimental study to assess the reliability of a new grip-like titanium device (Skull Grip) versus traditional sutures: technical note.
    Minimally invasive neurosurgery : MIN, 2009, Volume: 52, Issue:2

    Topics: Cadaver; Craniotomy; Humans; Neurosurgical Procedures; Osteolysis; Plastic Surgery Procedures; Postoperative Complications; Prostheses and Implants; Pseudarthrosis; Reproducibility of Results; Skull; Stress, Mechanical; Surgical Flaps; Titanium; Treatment Outcome; Weight-Bearing; Wound Healing

2009
Low dose metal particles can induce monocyte/macrophage survival.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2009, Volume: 27, Issue:11

    Topics: Alloys; Animals; Cell Survival; Cells, Cultured; Chromium Alloys; Culture Media, Conditioned; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; Macrophage Colony-Stimulating Factor; Macrophages; Metals; Mice; Monocytes; Osteolysis; Titanium

2009
Reduction of particle-induced osteolysis by interleukin-6 involves anti-inflammatory effect and inhibition of early osteoclast precursor differentiation.
    Bone, 2009, Volume: 45, Issue:4

    Topics: Animals; CD11b Antigen; Cell Differentiation; Inflammation; Interleukin-6; Macrophage Colony-Stimulating Factor; Mice; Osteoclasts; Osteogenesis; Osteolysis; Spleen; Stem Cells; Titanium; Tumor Necrosis Factor-alpha

2009
Severe periprosthetic osteolytic lesions after the Ankle Evolutive System total ankle replacement.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:7

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Ankle Joint; Arthroplasty, Replacement; Durapatite; Female; Humans; Image Interpretation, Computer-Assisted; Joint Prosthesis; Male; Middle Aged; Osteolysis; Radiography; Titanium; Young Adult

2009
Cemented total hip replacement cable debris and acetabular construct durability.
    The Journal of bone and joint surgery. American volume, 2009, Volume: 91, Issue:7

    Topics: Acetabulum; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cementation; Chromium Alloys; Follow-Up Studies; Hip Prosthesis; Humans; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Stainless Steel; Survival Analysis; Titanium

2009
Microscopic observations and inflammatory cytokine productions of human macrophage phagocytising submicron titanium particles.
    Journal of materials science. Materials in medicine, 2010, Volume: 21, Issue:1

    Topics: Cell Survival; Cells, Cultured; Cytokines; Humans; Inflammation Mediators; Macrophages; Microscopy, Electron, Scanning; Nanoparticles; Osteolysis; Particle Size; Phagocytosis; Titanium

2010
Backside volumetric change in the polyethylene of uncemented acetabular components.
    The Journal of bone and joint surgery. British volume, 2009, Volume: 91, Issue:8

    Topics: Acetabulum; Aged; Arthroplasty, Replacement, Hip; Female; Finite Element Analysis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium

2009
The effect of osteoprotegerin gene modification on wear debris-induced osteolysis in a murine model of knee prosthesis failure.
    Biomaterials, 2009, Volume: 30, Issue:30

    Topics: Animals; Dependovirus; Interleukin-1; Knee Prosthesis; Mice; Mice, Inbred BALB C; Osteolysis; Osteoprotegerin; Prosthesis Design; Prosthesis Failure; RANK Ligand; RNA, Messenger; Time Factors; Tissue Distribution; Titanium; Transgenes; Tumor Necrosis Factor-alpha

2009
High survival of uncemented proximally porous-coated titanium alloy femoral stems in osteoporotic bone.
    Clinical orthopaedics and related research, 2010, Volume: 468, Issue:2

    Topics: Aged; Alloys; Arthroplasty, Replacement, Hip; Coated Materials, Biocompatible; Female; Femur; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Linear Models; Male; Middle Aged; Osteolysis; Osteoporosis; Pain; Pain Measurement; Porosity; Prosthesis Design; Prosthesis Failure; Radiography; Recovery of Function; Retrospective Studies; Severity of Illness Index; Stress, Mechanical; Surface Properties; Time Factors; Titanium; Treatment Outcome

2010
Promotion of bone formation by naringin in a titanium particle-induced diabetic murine calvarial osteolysis model.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:4

    Topics: Animals; Bone Substitutes; Collagen Type I; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Drugs, Chinese Herbal; Flavanones; Fracture Healing; Male; Mice; Mice, Inbred C57BL; Osteocalcin; Osteogenesis; Osteolysis; Peptides; Phytotherapy; Plant Extracts; Polypodiaceae; Skull; Titanium; Tomography, X-Ray Computed

2010
Protection against titanium particle induced osteolysis by cannabinoid receptor 2 selective antagonist.
    Biomaterials, 2010, Volume: 31, Issue:8

    Topics: Animals; Female; Humans; Indoles; Mice; Mice, Inbred BALB C; Osteoclasts; Osteolysis; Particle Size; Prosthesis Failure; RANK Ligand; Receptor, Cannabinoid, CB2; Skull; Titanium

2010
The effects of local and systemic alendronate delivery on wear debris-induced osteolysis in vivo.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:7

    Topics: Absorptiometry, Photon; Alendronate; Animals; Biomechanical Phenomena; Biopsy; Bone Cements; Bone Density; Bone Density Conservation Agents; Dose-Response Relationship, Drug; Injections, Subcutaneous; Knee Joint; Male; Osteolysis; Polymethyl Methacrylate; Rabbits; Titanium

2010
Osteopontin deficiency impairs wear debris-induced osteolysis via regulation of cytokine secretion from murine macrophages.
    Arthritis and rheumatism, 2010, Volume: 62, Issue:5

    Topics: Animals; Cells, Cultured; Chemokine CCL3; Cytokines; Disease Models, Animal; Female; I-kappa B Proteins; Interleukin-1alpha; Interleukin-1beta; Interleukin-6; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Osteolysis; Osteopontin; Phagocytosis; Skull; Titanium; Tumor Necrosis Factor-alpha

2010
Individual susceptibility to periprosthetic osteolysis is associated with altered patterns of innate immune gene expression in response to pro-inflammatory stimuli.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:9

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Case-Control Studies; Cytokines; Female; Humans; Leukocytes, Mononuclear; Lipopolysaccharides; Male; Osteolysis; Polyethylene; Postoperative Complications; Prosthesis Failure; Reoperation; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Titanium

2010
Treating lumbar spinal canal stenosis by injecting insoluble particles.
    Medical hypotheses, 2010, Volume: 75, Issue:3

    Topics: Humans; Lumbar Vertebrae; Osteolysis; Particulate Matter; Polyethylene; Spinal Stenosis; Titanium

2010
[Medium-term results of anatomic straight-shaft IMAGE implantation in primary hip joint endoprosthetics--a prospective study].
    Zeitschrift fur Orthopadie und Unfallchirurgie, 2010, Volume: 148, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Alloys; Biomechanical Phenomena; Bone Remodeling; Equipment Failure Analysis; Female; Femur; Hip Prosthesis; Humans; Hyperostosis; Image Processing, Computer-Assisted; Male; Middle Aged; Osseointegration; Osteolysis; Postoperative Complications; Prospective Studies; Prosthesis Design; Titanium; Tomography, X-Ray Computed; Weight-Bearing

2010
Efficacy of periprosthetic erythromycin delivery for wear debris-induced inflammation and osteolysis.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2010, Volume: 59, Issue:12

    Topics: Animals; Anti-Bacterial Agents; Coated Materials, Biocompatible; Erythromycin; Humans; Implants, Experimental; Inflammation; Osteolysis; Polyethylenes; Prosthesis Failure; Rats; Rats, Sprague-Dawley; Tibia; Titanium

2010
Inhibition of titanium particle-induced inflammatory osteolysis through inactivation of cannabinoid receptor 2 by AM630.
    Journal of biomedical materials research. Part A, 2010, Volume: 95, Issue:1

    Topics: Animals; Cell Survival; Cells, Cultured; Cytokines; Gene Expression Regulation; Indoles; Inflammation; Inflammation Mediators; Mice; Microscopy, Electron, Scanning; Osteoclasts; Osteogenesis; Osteolysis; Receptor, Cannabinoid, CB2; Titanium

2010
Periprosthetic osteolysis: characterizing the innate immune response to titanium wear-particles.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2010, Volume: 28, Issue:11

    Topics: Animals; Arthroplasty, Replacement, Hip; Carrier Proteins; Cells, Cultured; Humans; Immunity, Innate; Interleukin-1; Macrophages; Mice; Mice, Inbred C57BL; Neutrophil Infiltration; NLR Family, Pyrin Domain-Containing 3 Protein; Osteolysis; Titanium

2010
Midterm results of 506 solid trispiked reflection cementless acetabular components for primary total hip arthroplasty.
    The Journal of arthroplasty, 2011, Volume: 26, Issue:8

    Topics: Acetabulum; Adult; Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cohort Studies; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Incidence; Kaplan-Meier Estimate; Longitudinal Studies; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Prospective Studies; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Sex Factors; Titanium; Treatment Outcome

2011
High rate of osteolytic lesions in medium-term followup after the AES total ankle replacement.
    Foot & ankle international, 2011, Volume: 32, Issue:2

    Topics: Adult; Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Ankle; Coated Materials, Biocompatible; Durapatite; Female; Follow-Up Studies; Humans; Joint Prosthesis; Male; Middle Aged; Osteoarthritis; Osteolysis; Prosthesis Design; Radiography; Reoperation; Retrospective Studies; Titanium; Young Adult

2011
Polymethylmethacrylate and titanium alloy particles activate peripheral monocytes during periprosthetic inflammation and osteolysis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2011, Volume: 29, Issue:5

    Topics: Alloys; Animals; Arthroplasty, Replacement; Bone Transplantation; Humans; Inflammation; Leukocytes, Mononuclear; Mice; Mice, SCID; Osteolysis; Polymethyl Methacrylate; Titanium; Transplantation, Heterologous; X-Ray Microtomography

2011
Vascular endothelial growth factor gene silencing suppresses wear debris-induced inflammation.
    International orthopaedics, 2011, Volume: 35, Issue:12

    Topics: Alloys; Animals; Bone Resorption; Disease Models, Animal; Female; Gene Silencing; Genetic Vectors; Inflammation; Lentivirus; Mice; Mice, Inbred BALB C; MicroRNAs; Osteolysis; Prosthesis Failure; Titanium; Transfection; Vascular Endothelial Growth Factor A

2011
Silent soft tissue pathology is common with a modern metal-on-metal hip arthroplasty.
    Acta orthopaedica, 2011, Volume: 82, Issue:3

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Chromium; Cobalt; Edema; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium; Treatment Outcome

2011
PI3Kγ deletion reduces variability in the in vivo osteolytic response induced by orthopaedic wear particles.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2011, Volume: 29, Issue:11

    Topics: Animals; Class Ib Phosphatidylinositol 3-Kinase; Female; Macrophages; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Osteitis; Osteolysis; Parietal Bone; Polyethylene; Prosthesis Failure; Signal Transduction; Titanium

2011
Posterior condyle surface damage on retrieved femoral knee components.
    The Journal of arthroplasty, 2011, Volume: 26, Issue:8

    Topics: Arthroplasty, Replacement, Knee; Chromium Alloys; Female; Femur; Humans; Knee Joint; Knee Prosthesis; Male; Microscopy, Electron, Scanning; Niobium; Osteoarthritis, Knee; Osteolysis; Prosthesis Design; Prosthesis Failure; Range of Motion, Articular; Reoperation; Retrospective Studies; Surface Properties; Titanium; Zirconium

2011
Protective effects of COX-2 inhibitor on titanium-particle-induced inflammatory osteolysis via the down-regulation of RANK/RANKL.
    Acta biomaterialia, 2011, Volume: 7, Issue:8

    Topics: Acid Phosphatase; Animals; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Down-Regulation; Immunohistochemistry; Interleukin-1beta; Isoenzymes; Isoxazoles; Membranes; Mice; Mice, Inbred BALB C; Osteoclasts; Osteogenesis; Osteolysis; Particulate Matter; Protective Agents; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Tartrate-Resistant Acid Phosphatase; Titanium; Tumor Necrosis Factor-alpha

2011
Inhibitory effect of (-)-epigallocatechin gallate on titanium particle-induced TNF-α release and in vivo osteolysis.
    Experimental & molecular medicine, 2011, Jul-30, Volume: 43, Issue:7

    Topics: Animals; Catechin; Cell Line; Implants, Experimental; Macrophages; Male; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase 8; NF-kappa B; Osteolysis; Particulate Matter; Prosthesis Failure; Signal Transduction; Skull; Titanium; Transcription Factor AP-1; Tumor Necrosis Factor-alpha

2011
Second-generation modular acetabular components provide fixation at 10 to 16 years.
    Clinical orthopaedics and related research, 2012, Volume: 470, Issue:2

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Bone Cements; Bone Screws; Female; Hip Joint; Hip Prosthesis; Humans; Kaplan-Meier Estimate; Male; Middle Aged; North Carolina; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Range of Motion, Articular; Recovery of Function; Reoperation; Retrospective Studies; Risk Assessment; Risk Factors; Time Factors; Titanium; Treatment Outcome; Young Adult

2012
Low-dose captopril inhibits wear debris-induced inflammatory osteolysis.
    The Journal of international medical research, 2011, Volume: 39, Issue:3

    Topics: Animals; Base Sequence; Captopril; Cytokines; DNA Primers; Dose-Response Relationship, Drug; Female; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Osteolysis; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Titanium

2011
The potential role of human osteoblasts for periprosthetic osteolysis following exposure to wear particles.
    International journal of molecular medicine, 2011, Volume: 28, Issue:6

    Topics: Apoptosis; Arthroplasty, Replacement, Hip; Biocompatible Materials; Bone Cements; Bone Substitutes; Collagen Type I; Enzyme-Linked Immunosorbent Assay; Humans; Interleukin-6; Interleukin-8; Materials Testing; Matrix Metalloproteinase 1; Osteoblasts; Osteolysis; Particle Size; Polymethyl Methacrylate; Primary Cell Culture; Prostheses and Implants; Stainless Steel; Titanium; Vascular Endothelial Growth Factor A; Zirconium

2011
Actin and ERK1/2-CEBPβ signaling mediates phagocytosis-induced innate immune response of osteoprogenitor cells.
    Biomaterials, 2011, Volume: 32, Issue:35

    Topics: Actins; Adhesiveness; Animals; Benzimidazoles; Bone and Bones; CCAAT-Enhancer-Binding Protein-beta; Cyclooxygenase 2; Cytochalasin D; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Humans; Immunity, Innate; Inflammation; Interleukin-6; MAP Kinase Signaling System; Mice; Models, Biological; Osteogenesis; Osteolysis; Phagocytosis; Protein Kinase Inhibitors; Signal Transduction; Skull; Stem Cells; Time Factors; Titanium

2011
Macrophage response to high number of titanium particles is cytotoxic and COX-2 mediated and it is not affected by the particle's endotoxin content or the cleaning treatment.
    Journal of biomedical materials research. Part A, 2011, Dec-15, Volume: 99, Issue:4

    Topics: Animals; Bone and Bones; Cell Line; Cell Survival; Cyclooxygenase 2; Dinoprostone; Endotoxins; Macrophage Activation; Macrophages; Materials Testing; Mice; Osteolysis; Particle Size; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha

2011
Therapeutic potential of the proteasome inhibitor Bortezomib on titanium particle-induced inflammation in a murine model.
    Inflammation, 2012, Volume: 35, Issue:3

    Topics: Animals; Boronic Acids; Bortezomib; Female; I-kappa B Kinase; Inflammation; Inflammation Mediators; Joint Prosthesis; Mice; Mice, Inbred BALB C; NF-kappa B; Osteolysis; Prosthesis Failure; Proteasome Inhibitors; Pyrazines; Random Allocation; Titanium; Tumor Necrosis Factor-alpha

2012
Biological responses of human mesenchymal stem cells to titanium wear debris particles.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2012, Volume: 30, Issue:6

    Topics: Adherens Junctions; Apoptosis; Cell Adhesion; Cell Proliferation; Cell Survival; Cells, Cultured; Culture Media, Conditioned; Cytoskeleton; Dose-Response Relationship, Drug; Endocytosis; Gene Expression; Gene Expression Profiling; Humans; Interleukin-6; Interleukin-8; Mesenchymal Stem Cells; Osteogenesis; Osteolysis; Particulate Matter; Titanium

2012
Involvement of extracellular Hsp72 in wear particle-mediated osteolysis.
    Acta biomaterialia, 2012, Volume: 8, Issue:3

    Topics: Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cells, Cultured; Female; Hip Prosthesis; HSP72 Heat-Shock Proteins; Humans; Inflammation; Interleukin-1beta; Macrophage Activation; Male; Middle Aged; Osteoclasts; Osteolysis; Prosthesis Failure; Titanium; Tumor Necrosis Factor-alpha

2012
Protection against titanium particle-induced inflammatory osteolysis by the proteasome inhibitor bortezomib in vivo.
    Inflammation, 2012, Volume: 35, Issue:4

    Topics: Animals; Antigens, CD; Antigens, Differentiation, Myelomonocytic; Apoptosis; Arthroplasty, Replacement; Boronic Acids; Bortezomib; Female; Inflammation; Mice; Mice, Inbred BALB C; Osteolysis; Osteoprotegerin; Prosthesis Failure; Proteasome Inhibitors; Pyrazines; Random Allocation; RANK Ligand; Titanium; TNF Receptor-Associated Factor 6; Vascular Endothelial Growth Factors

2012
A concise minimum eight year follow-up of proximally porous-coated tapered titanium femoral stem in primary total hip arthroplasty.
    International orthopaedics, 2012, Volume: 36, Issue:8

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Incidence; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Patient Satisfaction; Porosity; Prospective Studies; Radiography; Retrospective Studies; Titanium; Treatment Outcome

2012
Prevention of wear particle-induced osteolysis by a novel V-ATPase inhibitor saliphenylhalamide through inhibition of osteoclast bone resorption.
    PloS one, 2012, Volume: 7, Issue:4

    Topics: Amides; Animals; Anti-Bacterial Agents; Arthroplasty, Replacement; Cell Polarity; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Mice; NF-kappa B; Osteoclasts; Osteolysis; RANK Ligand; Salicylates; Signal Transduction; Skull; Titanium; Vacuolar Proton-Translocating ATPases

2012
Inhibitory effects of luteolin on titanium particle-induced osteolysis in a mouse model.
    Acta biomaterialia, 2012, Volume: 8, Issue:9

    Topics: Animals; Base Sequence; Cell Differentiation; Culture Media, Conditioned; Disease Models, Animal; DNA Primers; Luteolin; Male; Mice; Mice, Inbred ICR; Osteoclasts; Osteolysis; Prostheses and Implants; Reverse Transcriptase Polymerase Chain Reaction; Titanium

2012
In vitro comparison of the biological activity of alumina ceramic and titanium particles associated with aseptic loosening.
    Biomedical materials (Bristol, England), 2012, Volume: 7, Issue:4

    Topics: Aluminum Oxide; Animals; Biocompatible Materials; Cell Line; Cytokines; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation; In Vitro Techniques; Inflammation; Joint Prosthesis; Macrophages; Mice; Osteolysis; Particle Size; Polymerase Chain Reaction; Prosthesis Design; RANK Ligand; Titanium; Tumor Necrosis Factor-alpha

2012
Inhibition of p38 mitogen-activated protein kinase down-regulates the inflammatory osteolysis response to titanium particles in a murine osteolysis model.
    Inflammation, 2012, Volume: 35, Issue:6

    Topics: Acid Phosphatase; Animals; Bone and Bones; Down-Regulation; Enzyme Inhibitors; Female; Imidazoles; Inflammation; Isoenzymes; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Osteoclasts; Osteolysis; p38 Mitogen-Activated Protein Kinases; Pyridines; RNA, Messenger; Tartrate-Resistant Acid Phosphatase; Titanium; Tumor Necrosis Factor-alpha

2012
Second-generation uncemented stems: excellent 5-13-year results.
    Archives of orthopaedic and trauma surgery, 2009, Volume: 129, Issue:12

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Bone Cements; Female; Femoral Fractures; Femur; Hip; Humans; Hypertrophy; Male; Middle Aged; Osteolysis; Pain; Postoperative Complications; Prospective Studies; Prosthesis Design; Prosthesis Failure; Radiography; Titanium; Treatment Outcome; Young Adult

2009
MMP-9 inhibition suppresses wear debris-induced inflammatory osteolysis through downregulation of RANK/RANKL in a murine osteolysis model.
    International journal of molecular medicine, 2012, Volume: 30, Issue:6

    Topics: Animals; Arthroplasty; Cell Differentiation; Drug Evaluation, Preclinical; Female; Gene Expression; Gene Expression Regulation, Enzymologic; Matrix Metalloproteinase 9; Mice; Mice, Inbred BALB C; Osteitis; Osteoclasts; Osteolysis; Particulate Matter; Prosthesis Failure; Protein Synthesis Inhibitors; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Tetracycline; Titanium; Tumor Necrosis Factor-alpha

2012
Influence of statins locally applied from orthopedic implants on osseous integration.
    BMC musculoskeletal disorders, 2012, Oct-26, Volume: 13

    Topics: Animals; Biomechanical Phenomena; Coated Materials, Biocompatible; Dose-Response Relationship, Drug; Female; Femur; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Osseointegration; Osteolysis; Polyesters; Prosthesis Design; Prosthesis Implantation; Radiography; Rats; Rats, Sprague-Dawley; Simvastatin; Time Factors; Titanium

2012
Ten- to 15-year clinical and radiographic results for a compression molded monoblock elliptical acetabular component.
    The Journal of arthroplasty, 2012, Volume: 27, Issue:10

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium; Treatment Outcome

2012
Viral interleukin-10 gene inhibition of inflammation, osteoclastogenesis, and bone resorption in response to titanium particles.
    Arthritis and rheumatism, 2002, Volume: 46, Issue:5

    Topics: Adenoviridae; Animals; Cells, Cultured; Fibroblasts; Genetic Therapy; Genetic Vectors; Inflammation; Interleukin-1; Interleukin-10; Interleukin-6; Macrophages; Osteoclasts; Osteolysis; Skull; Spleen; Synovial Membrane; Titanium; Transduction, Genetic; Transgenes; Tumor Necrosis Factor-alpha; Viral Proteins

2002
Gene expression analysis of osteoblastic cells contacted by orthopedic implant particles.
    Journal of biomedical materials research, 2002, Sep-05, Volume: 61, Issue:3

    Topics: Animals; Apoptosis; Biocompatible Materials; Caspase 3; Caspases; Cell Culture Techniques; Gene Expression Profiling; Humans; Joint Prosthesis; Osteoblasts; Osteolysis; Particle Size; Prosthesis Failure; Rats; Titanium

2002
The influence of biomaterial on patterns of failure after cemented total hip replacement.
    International orthopaedics, 2002, Volume: 26, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Biocompatible Materials; Cementation; Chromium; Cobalt; Equipment Failure Analysis; Female; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Statistics, Nonparametric; Titanium

2002
The effect of titanium particulate on development and maintenance of a posterolateral spinal arthrodesis: an in vivo rabbit model.
    Spine, 2002, Sep-15, Volume: 27, Issue:18

    Topics: Acid Phosphatase; Animals; Apoptosis; Bone Transplantation; Cell Count; Cytokines; Ilium; Immunohistochemistry; Implants, Experimental; Inflammation; Lumbar Vertebrae; Macrophages; Models, Animal; Osteoclasts; Osteolysis; Particle Size; Rabbits; Radiography; Spinal Fusion; Titanium; Treatment Outcome; Tumor Necrosis Factor-alpha

2002
Case report: metaphyseal osteolysis around a titanium reconstruction nail.
    Injury, 2003, Volume: 34, Issue:5

    Topics: Bone Nails; Bone Screws; Female; Femoral Fractures; Fracture Fixation, Intramedullary; Humans; Middle Aged; Osteolysis; Postoperative Complications; Radiography; Titanium

2003
Premature failure of a hip hemiarthroplasty secondary to osteolysis and aseptic loosening.
    American journal of orthopedics (Belle Mead, N.J.), 2003, Volume: 32, Issue:4

    Topics: Aged; Arthroplasty; Arthroplasty, Replacement, Hip; Foreign-Body Reaction; Hip Prosthesis; Humans; Male; Osteolysis; Polyethylenes; Prosthesis Failure; Reoperation; Surface Properties; Titanium

2003
Long-term radiographic changes in cemented total hip arthroplasty with six designs of femoral components.
    Biomaterials, 2003, Volume: 24, Issue:19

    Topics: Aged; Alloys; Arthroplasty, Replacement, Hip; Bone Cements; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Stainless Steel; Time Factors; Titanium

2003
Biological reaction to alumina, zirconia, titanium and polyethylene particles implanted onto murine calvaria.
    Biomaterials, 2003, Volume: 24, Issue:21

    Topics: Aluminum; Animals; Arthroplasty, Replacement, Hip; Biocompatible Materials; Bone Substitutes; Ceramics; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Hip Prosthesis; Interleukin-1; Interleukin-6; Mice; Microscopy, Electron; Organ Culture Techniques; Osteolysis; Polyethylene; Prostheses and Implants; Time Factors; Titanium; Tumor Necrosis Factor-alpha; Zirconium

2003
A comparison of cemented and cementless titanium femoral components used for primary total hip arthroplasty: a radiographic and survivorship study. By Emerson RH Jr, et al.
    The Journal of arthroplasty, 2003, Volume: 18, Issue:4

    Topics: Acetabulum; Arthroplasty, Replacement, Hip; Cementation; Equipment Failure Analysis; Femur; Hip Prosthesis; Humans; Osteolysis; Prosthesis Design; Radiography; Reoperation; Titanium

2003
Periprosthetic osteolysis: induction of vascular endothelial growth factor from human monocyte/macrophages by orthopaedic biomaterial particles.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2003, Volume: 18, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Base Sequence; Biocompatible Materials; Cells, Cultured; Chemotaxis; DNA, Complementary; Extracellular Matrix Proteins; Female; Humans; In Vitro Techniques; Joint Prosthesis; Macrophages; Male; MAP Kinase Signaling System; Middle Aged; Models, Biological; Monocytes; Osteolysis; Prosthesis Failure; RNA, Messenger; Titanium; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1

2003
Spinal implant debris-induced osteolysis.
    Spine, 2003, Oct-15, Volume: 28, Issue:20

    Topics: Adult; Animals; Apoptosis; Arthroplasty, Replacement; Humans; Inflammation; Interleukin-1; Interleukin-6; Macrophages; Microscopy, Electron, Transmission; Models, Biological; Osteoclasts; Osteolysis; Particle Size; Prostheses and Implants; Rabbits; Spine; Stainless Steel; Titanium; Tumor Necrosis Factor-alpha

2003
PGE2 and IL-6 production by fibroblasts in response to titanium wear debris particles is mediated through a Cox-2 dependent pathway.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2004, Volume: 22, Issue:1

    Topics: Animals; Cell Line; Cyclooxygenase 2; Dinoprostone; Fibroblasts; In Vitro Techniques; Interleukin-6; Isoenzymes; Mice; Mice, Inbred CBA; Osteolysis; Prostaglandin-Endoperoxide Synthases; Prosthesis Failure; Titanium

2004
Effect of cyclic mechanical stretch and titanium particles on prostaglandin E2 production by human macrophages in vitro.
    Journal of biomedical materials research. Part A, 2004, Mar-01, Volume: 68, Issue:3

    Topics: Cyclooxygenase 2; Dinoprostone; Equipment Failure Analysis; Humans; Isoenzymes; Joint Prosthesis; Kinetics; Macrophages; Membrane Proteins; Osteolysis; Prostaglandin-Endoperoxide Synthases; RNA, Messenger; Stress, Mechanical; Titanium

2004
Effects of interleukin-10 on titanium particle-induced macrophage transcription factor activation and cytokine expression in vitro.
    Journal of biomedical materials research. Part A, 2004, Apr-01, Volume: 69, Issue:1

    Topics: CCAAT-Enhancer-Binding Protein-beta; Cytokines; Humans; Interleukin-10; Joint Prosthesis; Macrophage Activation; Macrophages; NF-kappa B; Osteolysis; Titanium

2004
The effectiveness of polyethylene versus titanium particles in inducing osteolysis in vivo.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2004, Volume: 22, Issue:2

    Topics: Animals; Disease Models, Animal; Female; Giant Cells, Foreign-Body; Macrophages; Male; Mice; Mice, Inbred C57BL; Osteoclasts; Osteolysis; Particle Size; Polyethylene; Skull; Titanium; Wound Healing

2004
Wear-particle-induced osteoclast osteolysis: the role of particulates and mechanical strain.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2004, Apr-15, Volume: 69, Issue:1

    Topics: Animals; Antibodies; Apoptosis; Bone Marrow; Carrier Proteins; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Chromium Alloys; Eicosanoids; Glycoproteins; Membrane Glycoproteins; Mice; Osteoclasts; Osteolysis; Osteoprotegerin; Particle Size; Plastics; Polyethylene; Rabbits; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Solubility; Stress, Mechanical; Surface Properties; Titanium

2004
Wear of a highly cross-linked polyethylene liner associated with metallic deposition on a ceramic femoral head.
    The Journal of arthroplasty, 2004, Volume: 19, Issue:4

    Topics: Aged; Aluminum Oxide; Arthroplasty, Replacement, Hip; Hip Dislocation; Humans; Male; Microscopy, Electron, Scanning; Osteolysis; Polyethylene; Prosthesis Failure; Radiography; Reoperation; Surface Properties; Titanium

2004
The role of implant alignment on stability and particles on periprosthetic osteolysis--A rabbit model of implant failure.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2004, Aug-15, Volume: 70, Issue:2

    Topics: Alloys; Animals; Arthroplasty; Foreign-Body Reaction; Implants, Experimental; Osteolysis; Polyethylenes; Prosthesis Failure; Rabbits; Tibia; Titanium

2004
Proinflammatory mediator expression in a novel murine model of titanium-particle-induced intramedullary inflammation.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2004, Nov-15, Volume: 71, Issue:2

    Topics: Animals; Biocompatible Materials; Chemokine CCL2; Enzyme-Linked Immunosorbent Assay; Femur; Histocytochemistry; Inflammation Mediators; Interleukin-6; Macrophage Colony-Stimulating Factor; Mice; Organ Culture Techniques; Osteolysis; Prostheses and Implants; Radiography; Stainless Steel; Titanium; Tumor Necrosis Factor-alpha

2004
Expression of inflammatory cytokines, RANKL and OPG induced by titanium, cobalt-chromium and polyethylene particles.
    Biomaterials, 2005, Volume: 26, Issue:14

    Topics: Animals; Biocompatible Materials; Carrier Proteins; Chromium Alloys; Foreign-Body Reaction; Gene Expression Regulation; Glycoproteins; Materials Testing; Membrane Glycoproteins; Men; Mice; Mice, Inbred C57BL; Microspheres; Osteolysis; Osteoprotegerin; Particle Size; Polyethylene; Prosthesis-Related Infections; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Titanium

2005
Gene expression clustering using self-organizing maps: analysis of the macrophage response to particulate biomaterials.
    Biomaterials, 2005, Volume: 26, Issue:16

    Topics: Algorithms; Alloys; Biocompatible Materials; Cluster Analysis; DNA, Complementary; Down-Regulation; Gene Expression Regulation; Humans; Image Processing, Computer-Assisted; Inflammation; Ligands; Macrophages; Male; Monocytes; Multigene Family; Oligonucleotide Array Sequence Analysis; Osteolysis; Phagocytosis; Polyethylene; Polyethylenes; Prosthesis Failure; RNA, Messenger; Signal Transduction; Statistics as Topic; Time Factors; Titanium; Up-Regulation

2005
Polyethylene and titanium particles induce osteolysis by similar, lymphocyte-independent, mechanisms.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:2

    Topics: Animals; Arthroplasty, Replacement; Cytokines; Lymphocytes; Mice; Mice, Inbred C57BL; Osteolysis; Polyethylene; Titanium

2005
Ten to twelve-year results with the Zweymüller cementless total hip prosthesis.
    The Journal of arthroplasty, 2005, Volume: 20, Issue:3

    Topics: Aged; Bone Cements; Ceramics; Equipment Failure Analysis; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Postoperative Complications; Prosthesis Design; Radiography; Reoperation; Titanium

2005
Radiographic evaluation of a monoblock acetabular component: a multicenter study with 2- to 5-year results.
    The Journal of arthroplasty, 2005, Volume: 20, Issue:3

    Topics: Acetabulum; Biomechanical Phenomena; Coated Materials, Biocompatible; Equipment Failure Analysis; Follow-Up Studies; Fracture Healing; Fractures, Bone; Hip Dislocation, Congenital; Hip Prosthesis; Humans; Osseointegration; Osteoarthritis, Hip; Osteolysis; Postoperative Complications; Prosthesis Design; Radiography; Tantalum; Titanium

2005
Activation of NF-kappaB signalling and TNFalpha-expression in THP-1 macrophages by TiAlV- and polyethylene-wear particles.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:6

    Topics: Alloys; Arthroplasty, Replacement, Knee; Cells, Cultured; DNA; Humans; Macrophages; NF-kappa B; Osteolysis; Polyethylene; Promoter Regions, Genetic; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha

2005
Sphingomyelinase mediates macrophage activation by titanium particles independent of phagocytosis: a role for free radicals, NFkappaB, and TNFalpha.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2005, Volume: 23, Issue:6

    Topics: Animals; Cell Line; Free Radicals; Glutathione; Macrophage Activation; Mice; NF-kappa B; Osteolysis; Phagocytosis; Sphingomyelin Phosphodiesterase; Titanium; Tumor Necrosis Factor-alpha

2005
Re: the LPM Titanium semi-constrained proximal interphalangeal joint replacement.
    Journal of hand surgery (Edinburgh, Scotland), 2006, Volume: 31, Issue:2

    Topics: Arthroplasty, Replacement; Finger Joint; Humans; Joint Prosthesis; Osteolysis; Titanium

2006
Particulate endocytosis mediates biological responses of human mesenchymal stem cells to titanium wear debris.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2006, Volume: 24, Issue:3

    Topics: Apoptosis; Arthroplasty, Replacement; Cell Adhesion; Cell Differentiation; Cell Proliferation; Cells, Cultured; Cytochalasin D; Endocytosis; Humans; Joint Prosthesis; Mesenchymal Stem Cells; Microscopy, Confocal; Osteogenesis; Osteolysis; Titanium

2006
Osteolysis caused by tibial component debonding in total knee arthroplasty.
    Clinical orthopaedics and related research, 2006, Volume: 443

    Topics: Aged; Arthroplasty, Replacement, Knee; Bone Cements; Follow-Up Studies; Humans; Male; Osteolysis; Prosthesis Failure; Radiography; Reoperation; Tibia; Titanium

2006
[Results of cementless hip arthroplasty].
    Der Radiologe, 2006, Volume: 46, Issue:9

    Topics: Austria; Bone Cements; Follow-Up Studies; Germany; Hip Prosthesis; Humans; Osseointegration; Osteolysis; Patient Satisfaction; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium

2006
Wear debris inhibition of anti-osteoclastogenic signaling by interleukin-6 and interferon-gamma. Mechanistic insights and implications for periprosthetic osteolysis.
    The Journal of bone and joint surgery. American volume, 2006, Volume: 88, Issue:4

    Topics: Bone Cements; Cells, Cultured; Humans; Interferon-gamma; Interleukin-6; Joint Prosthesis; Mitogen-Activated Protein Kinases; Osteoclasts; Osteolysis; Polymethyl Methacrylate; Titanium

2006
Metallosis after contemporary metal-on-metal total hip arthroplasty. Five to nine-year follow-up.
    The Journal of bone and joint surgery. American volume, 2006, Volume: 88, Issue:6

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Hypersensitivity; Joint Diseases; Male; Middle Aged; Niobium; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Time Factors; Titanium; Vitallium

2006
Involvement of complement receptor 3 (CR3) and scavenger receptor in macrophage responses to wear debris.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2006, Volume: 24, Issue:11

    Topics: Fibronectins; Humans; Lipopolysaccharide Receptors; Macrophages; Monocytes; Opsonin Proteins; Osteolysis; Phagocytosis; Polymethacrylic Acids; Prosthesis Failure; Receptors, Complement 3b; RNA, Messenger; Scavenger Receptors, Class A; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha

2006
The potential for bone loss in acetabular structures following THA.
    Clinical orthopaedics and related research, 2006, Volume: 453

    Topics: Acetabulum; Arthroplasty, Replacement, Hip; Benzophenones; Biocompatible Materials; Biomechanical Phenomena; Chromium Alloys; Female; Finite Element Analysis; Hip Joint; Hip Prosthesis; Humans; Imaging, Three-Dimensional; In Vitro Techniques; Ketones; Middle Aged; Osteolysis; Polyethylene Glycols; Polyethylenes; Polymers; Prosthesis Design; Prosthesis Failure; Stress, Mechanical; Titanium

2006
The role of fibroblasts and fibroblast-derived factors in periprosthetic osteolysis.
    Arthritis and rheumatism, 2006, Volume: 54, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Knee; Bone Resorption; Cells, Cultured; Culture Media, Conditioned; Cytokines; Female; Fibroblasts; Gene Expression Regulation; Humans; Knee Prosthesis; Macrophage Colony-Stimulating Factor; Male; Middle Aged; Osteoclasts; Osteolysis; Osteoprotegerin; Phagocytosis; RANK Ligand; RNA, Messenger; Titanium; Vascular Endothelial Growth Factor A

2006
The balance between endotoxin accumulation and clearance during particle-induced osteolysis in murine calvaria.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2007, Volume: 25, Issue:3

    Topics: Animals; Endotoxins; Female; Germ-Free Life; Mice; Mice, Inbred C57BL; Osteolysis; Polyethylene; Prosthesis Failure; Skull; Titanium

2007
Wear-induced osteolysis and synovial swelling in a patient with a metal-polyethylene wrist prosthesis.
    The Journal of hand surgery, 2006, Volume: 31, Issue:10

    Topics: Adult; Corrosion; Humans; Joint Prosthesis; Lymphocytes; Macrophages; Male; Neutrophils; Osteolysis; Polyethylene; Prosthesis Failure; Reoperation; Stress, Mechanical; Synovitis; Titanium; Wrist Joint

2006
Comparison of the roles of IL-1, IL-6, and TNFalpha in cell culture and murine models of aseptic loosening.
    Bone, 2007, Volume: 40, Issue:5

    Topics: Animals; Antibodies; Asepsis; Cell Differentiation; Cells, Cultured; Female; Interleukin-1; Interleukin-6; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Osteoclasts; Osteolysis; Receptors, Interleukin-1; Receptors, Tumor Necrosis Factor, Type I; Receptors, Tumor Necrosis Factor, Type II; Titanium; Tumor Necrosis Factor-alpha

2007
Radiolucent lines and osteolysis along tapered straight cementless titanium hip stems: a comparison of 6-year and 10-year follow-up results in 95 patients.
    Acta orthopaedica, 2006, Volume: 77, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Joint Instability; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Titanium

2006
Administration of pamidronate alters bone-titanium attachment in the presence of endotoxin-coated polyethylene particles.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2007, Volume: 83, Issue:2

    Topics: Absorptiometry, Photon; Animals; Bone and Bones; Bone Density Conservation Agents; Diphosphonates; Endotoxins; Female; Femur; Hip Prosthesis; Injections, Intraperitoneal; Osteolysis; Pamidronate; Polyethylene; Rats; Rats, Sprague-Dawley; Titanium

2007
Calvarial defects associated with neurofibromatosis type 1. Report of two cases.
    Journal of neurosurgery, 2007, Volume: 106, Issue:6 Suppl

    Topics: Absorbable Implants; Adolescent; Bone Plates; Female; Head; Humans; Ilium; Imaging, Three-Dimensional; Male; Neurofibromatosis 1; Neurosurgical Procedures; Osteolysis; Skull; Surgical Mesh; Titanium; Tomography, X-Ray Computed

2007
Evolution of tibial fixation in total knee arthroplasty.
    The Journal of arthroplasty, 2007, Volume: 22, Issue:4 Suppl 1

    Topics: Arthroplasty, Replacement, Knee; Cementation; Humans; Osteolysis; Prosthesis Failure; Tantalum; Titanium

2007
Histomorphometric analysis of the intramedullary bone response to titanium particles in wild-type and IL-1R1 knock-out mice: a preliminary study.
    Journal of biomedical materials research. Part B, Applied biomaterials, 2008, Volume: 84, Issue:2

    Topics: Animals; Bone and Bones; Bone Nails; Femur; Interleukin-1; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Models, Animal; Osteolysis; Prosthesis Failure; Receptors, Interleukin-1 Type I; Titanium

2008
Second-generation proximally coated titanium femoral component: minimum 7-year results.
    Clinical orthopaedics and related research, 2007, Volume: 465

    Topics: Adult; Aged; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Male; Materials Testing; Middle Aged; Osseointegration; Osteolysis; Pain; Pain Measurement; Prospective Studies; Prosthesis Design; Radiography; Range of Motion, Articular; Recovery of Function; Time Factors; Titanium; Treatment Outcome

2007
Use of a hydroxyapatite-coated stem in patients with Dorr Type C femoral bone.
    Clinical orthopaedics and related research, 2007, Volume: 465

    Topics: Alloys; Arthroplasty, Replacement, Hip; Durapatite; Female; Femur; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osseointegration; Osteolysis; Prosthesis Design; Radiography; Range of Motion, Articular; Recovery of Function; Retrospective Studies; Time Factors; Titanium; Treatment Outcome

2007
Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2008, Volume: 26, Issue:1

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cells, Cultured; Cytokines; Female; Femur; Gene Expression Profiling; Humans; Macrophages; Male; Middle Aged; Osteoarthritis, Hip; Osteoclasts; Osteogenesis; Osteolysis; Polymethyl Methacrylate; Prosthesis Failure; Reverse Transcriptase Polymerase Chain Reaction; Synovial Membrane; Titanium

2008
Complex revision total hip arthroplasty with modular stems at a mean of 14 years.
    Clinical orthopaedics and related research, 2007, Volume: 465

    Topics: Arthroplasty, Replacement, Hip; Bone Transplantation; Femur; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Joint Instability; Osseointegration; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Stress, Mechanical; Time Factors; Titanium; Treatment Outcome

2007
Good stability and minimal osteolysis with a biconical threaded cup at 10 years.
    Clinical orthopaedics and related research, 2007, Volume: 463

    Topics: Adult; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cementation; Ceramics; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Joint Instability; Middle Aged; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Reoperation; Retrospective Studies; Titanium

2007
Severe bone defects and reduced mineralization caused by massive metallosis after total knee arthroplasty: histopathologic and bone morphometric findings.
    Modern rheumatology, 2007, Volume: 17, Issue:6

    Topics: Aged; Arthroplasty, Replacement, Knee; Bone Resorption; Calcification, Physiologic; Female; Foreign-Body Reaction; Humans; Osteogenesis; Osteolysis; Postoperative Complications; Prosthesis Failure; Radiography; Tetracycline; Tibia; Tibial Fractures; Titanium

2007
Reducing metal debris generation during total knee arthroplasty.
    Orthopedics, 2007, Volume: 30, Issue:12

    Topics: Animals; Arthroplasty, Replacement, Knee; Disease Models, Animal; Equipment Design; Materials Testing; Osteolysis; Particle Size; Postoperative Complications; Swine; Titanium

2007
Effect of component fixation method on osteolysis in total knee arthroplasty.
    Clinical orthopaedics and related research, 1995, Issue:321

    Topics: Aged; Aged, 80 and over; Alloys; Bone Cements; Bone Screws; Chromium Alloys; Follow-Up Studies; Humans; Knee Prosthesis; Middle Aged; Osteolysis; Postoperative Complications; Prosthesis Design; Radiography; Titanium

1995
The potential role of fibroblasts in periprosthetic osteolysis: fibroblast response to titanium particles.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 1995, Volume: 10, Issue:9

    Topics: Base Sequence; Bone Resorption; Fibroblasts; Hip Prosthesis; Humans; Metalloendopeptidases; Molecular Sequence Data; Osteolysis; Protein Biosynthesis; Reference Values; RNA, Messenger; Stimulation, Chemical; Synovial Membrane; Titanium

1995
Early failure of titanium alloy femoral components: a quantitative radiological analysis of osteolytic and granulomatous change.
    Journal of the Royal Society of Medicine, 1993, Volume: 86, Issue:8

    Topics: Aged; Aged, 80 and over; Alloys; Femur; Granuloma; Hip Prosthesis; Humans; Middle Aged; Osteolysis; Prosthesis Failure; Radiography; Time Factors; Titanium; Vitallium

1993
In vivo and in vitro analysis of membranes from hip prostheses inserted without cement.
    The Journal of bone and joint surgery. American volume, 1994, Volume: 76, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Bone Cements; Bone Resorption; Chromium Alloys; Collagenases; Dinoprostone; Female; Hip Prosthesis; Humans; Immunohistochemistry; Interleukin-1; Macrophage Activation; Macrophages; Male; Middle Aged; Osteolysis; Polyethylenes; Prosthesis Failure; Radiography; Reoperation; Titanium

1994
Hip replacement with a threaded acetabular cup. A follow-up study.
    The Journal of bone and joint surgery. American volume, 1994, Volume: 76, Issue:2

    Topics: Acetabulum; Adult; Aged; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium

1994
The relationship between the design, position, and articular wear of acetabular components inserted without cement and the development of pelvic osteolysis.
    The Journal of bone and joint surgery. American volume, 1994, Volume: 76, Issue:5

    Topics: Acetabulum; Adolescent; Adult; Aged; Body Fluids; Bone Cysts; Female; Follow-Up Studies; Foreign-Body Reaction; Hip Prosthesis; Humans; Hydrostatic Pressure; Ilium; Logistic Models; Male; Middle Aged; Osteolysis; Pelvic Bones; Polyethylenes; Porosity; Prosthesis Design; Prosthesis Failure; Prosthesis Fitting; Reoperation; Surface Properties; Titanium; Weight-Bearing

1994
Extensive osteolysis around an aseptic, stable, uncemented total knee replacement.
    Clinical orthopaedics and related research, 1993, Issue:293

    Topics: Bone Cements; Chromium; Cobalt; Femur; Humans; Knee Prosthesis; Male; Middle Aged; Osteolysis; Polyethylenes; Prosthesis Failure; Synovial Membrane; Titanium

1993
Osteolysis from a press-fit hydroxyapatite-coated implant. A case study.
    The Journal of arthroplasty, 1993, Volume: 8, Issue:2

    Topics: Acetabulum; Durapatite; Female; Foreign-Body Migration; Hip Prosthesis; Humans; Hydroxyapatites; Microscopy, Electron, Scanning; Middle Aged; Osteoarthritis; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Titanium

1993
Metal/metal articulating interfaces.
    Orthopedics, 1995, Volume: 18, Issue:9

    Topics: Hip Prosthesis; Humans; Metals; Osteolysis; Polyethylenes; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Surface Properties; Titanium

1995
Adsorption of collagenase to particulate titanium: a possible mechanism for collagenase localization in periprosthetic tissue.
    Journal of applied biomaterials : an official journal of the Society for Biomaterials, 1994,Winter, Volume: 5, Issue:4

    Topics: Adsorption; Amino Acid Sequence; Animals; Biocompatible Materials; Cells, Cultured; Collagenases; Equipment Failure; Female; Joint Prosthesis; Kinetics; L-Lactate Dehydrogenase; Latex; Macrophages, Peritoneal; Male; Mice; Mice, Inbred BALB C; Molecular Sequence Data; Osteolysis; Substrate Specificity; Time Factors; Titanium

1994
Increasing incidence of femoral osteolysis in association with uncemented Harris-Galante total hip arthroplasty. A follow-up report.
    The Journal of arthroplasty, 1996, Volume: 11, Issue:2

    Topics: Adult; Aged; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Radiography; Titanium

1996
Titanium, chromium and cobalt ions modulate the release of bone-associated cytokines by human monocytes/macrophages in vitro.
    Biomaterials, 1996, Volume: 17, Issue:23

    Topics: Biocompatible Materials; Cell Division; Cells, Cultured; Chromium; Cobalt; Corrosion; Cytokines; Humans; Interleukin-1; Interleukin-6; Joint Prosthesis; Lymphoma, Large B-Cell, Diffuse; Macrophages; Monocytes; Osteolysis; Prosthesis Failure; Titanium; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha

1996
Primary cementless hip arthroplasty with a titanium plasma sprayed prosthesis.
    Clinical orthopaedics and related research, 1996, Issue:333

    Topics: Adult; Aged; Arthritis, Rheumatoid; Cementation; Female; Femur Head Necrosis; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Prosthesis Design; Prosthesis Failure; Radiography; Retrospective Studies; Titanium

1996
Radiographic analysis of a cemented titanium alloy femoral component.
    Clinical orthopaedics and related research, 1997, Issue:334

    Topics: Aged; Alloys; Bone Density; Bone Remodeling; Cementation; Female; Femur; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Design; Radiography; Titanium

1997
Human monocyte/macrophage response to cobalt-chromium corrosion products and titanium particles in patients with total joint replacements.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1997, Volume: 15, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Bone Resorption; Calcium; Cell Division; Cell Line; Cell Membrane; Cell Survival; Chromium; Cobalt; Corrosion; Culture Media, Conditioned; Dinoprostone; Female; Fibroblasts; Hip Prosthesis; Humans; Interleukin-1; Joint Instability; Macrophages; Male; Materials Testing; Metals; Middle Aged; Monocytes; Organ Culture Techniques; Osteolysis; Titanium

1997
Three-dimensional polyethylene wear of a press-fit titanium prosthesis. Factors influencing generation of polyethylene debris.
    The Journal of arthroplasty, 1997, Volume: 12, Issue:3

    Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Femur Head Necrosis; Follow-Up Studies; Hip; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Polyethylenes; Postoperative Complications; Prosthesis Design; Radiography; Regression Analysis; Risk Factors; Titanium

1997
Results of the cementless Mallory-Head primary total hip arthroplasty: a 5 to 7 year review.
    The Iowa orthopaedic journal, 1996, Volume: 16

    Topics: Adult; Aged; Arthritis, Rheumatoid; Female; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Polyethylenes; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Titanium; Treatment Outcome

1996
Prosthetic metals interfere with the functions of human osteoblast cells in vitro.
    Clinical orthopaedics and related research, 1997, Issue:339

    Topics: Bone Neoplasms; Cell Division; Chromium; Cobalt; Cytokines; Humans; Joint Prosthesis; Osteoblasts; Osteocalcin; Osteolysis; Osteosarcoma; Titanium; Tumor Cells, Cultured

1997
Titanium prosthetic wear debris in remote bone marrow. A report of two cases.
    The Journal of bone and joint surgery. American volume, 1997, Volume: 79, Issue:11

    Topics: Acetabulum; Aged; Aluminum; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; Bone Marrow; Electron Probe Microanalysis; Female; Femoral Fractures; Fractures, Spontaneous; Hip Prosthesis; Humans; Knee Prosthesis; Male; Middle Aged; Osteolysis; Patella; Prosthesis Failure; Reoperation; Titanium; Vanadium

1997
Total hip arthroplasty with an uncemented femoral component. Excellent results at ten-year follow-up.
    The Journal of bone and joint surgery. British volume, 1997, Volume: 79, Issue:6

    Topics: Acetabulum; Adult; Aged; Aged, 80 and over; Alloys; Arthroplasty, Replacement, Hip; Cementation; Connective Tissue; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Linear Models; Male; Middle Aged; Multivariate Analysis; Osseointegration; Osteolysis; Prosthesis Design; Prosthesis Failure; Prosthesis-Related Infections; Radiography; Reoperation; Sepsis; Surface Properties; Survival Rate; Titanium; Treatment Outcome

1997
Short periods of oscillating fluid pressure directed at a titanium-bone interface in rabbits lead to bone lysis.
    Acta orthopaedica Scandinavica, 1998, Volume: 69, Issue:1

    Topics: Animals; Bone and Bones; Disease Models, Animal; Hydrostatic Pressure; Osseointegration; Osteogenesis; Osteolysis; Pressure; Prostheses and Implants; Rabbits; Time Factors; Titanium

1998
Experiences with metal on metal components in THR.
    Acta orthopaedica Belgica, 1997, Volume: 63 Suppl 1

    Topics: Alloys; Arthroplasty, Replacement, Hip; Ceramics; Chromium Alloys; Friction; Hip Prosthesis; Humans; Osteolysis; Polyethylenes; Prosthesis Design; Stress, Mechanical; Surface Properties; Titanium; Treatment Outcome

1997
Acetabular osteolysis with cementless cups: a 5 to 7 year follow-up.
    Acta orthopaedica Belgica, 1997, Volume: 63 Suppl 1

    Topics: Acetabulum; Adult; Age Factors; Aged; Aged, 80 and over; Arthroplasty, Replacement, Hip; Cementation; Female; Femur; Follow-Up Studies; Hip Prosthesis; Humans; Hypertrophy; Joint Diseases; Male; Middle Aged; Osteolysis; Pain; Prosthesis Design; Prosthesis Failure; Radiography; Reoperation; Retrospective Studies; Stress, Mechanical; Titanium; Walking

1997
The Furlong hydroxyapatite-coated total hip replacement in patients under age 51. A 6-year follow-up study.
    Acta orthopaedica Belgica, 1998, Volume: 64, Issue:1

    Topics: Acetabulum; Adult; Age Factors; Alloys; Arthroplasty, Replacement, Hip; Biocompatible Materials; Chi-Square Distribution; Durable Medical Equipment; Durapatite; Female; Femoral Fractures; Femur; Follow-Up Studies; Hip Dislocation; Hip Prosthesis; Humans; Intraoperative Complications; Joint Instability; Male; Middle Aged; Osseointegration; Osteolysis; Pain; Patient Satisfaction; Polyethylenes; Postoperative Complications; Prosthesis Design; Prosthesis Failure; Radiography; Range of Motion, Articular; Reoperation; Surface Properties; Titanium; Treatment Outcome

1998
Particulate debris presenting as radiographic dense masses following total knee arthroplasty.
    The Journal of arthroplasty, 1998, Volume: 13, Issue:3

    Topics: Aged; Arthritis, Rheumatoid; Arthroplasty, Replacement, Knee; Humans; Male; Middle Aged; Osteoarthritis; Osteolysis; Prosthesis Failure; Radiography; Titanium

1998
Fixation and metal release from the Tifit femoral stem prosthesis. 5-year follow-up of 64 cases.
    Acta orthopaedica Scandinavica, 1998, Volume: 69, Issue:4

    Topics: Adult; Aged; Alloys; Arthroplasty, Replacement, Hip; Bone Cements; Coated Materials, Biocompatible; Durapatite; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteoarthritis, Hip; Osteolysis; Pain, Postoperative; Prosthesis Design; Prosthesis Failure; Radiography; Titanium

1998
Induction of macrophage C-C chemokine expression by titanium alloy and bone cement particles.
    The Journal of bone and joint surgery. British volume, 1999, Volume: 81, Issue:1

    Topics: Antibodies, Monoclonal; Bone Cements; Chemokine CCL2; Chemokine CCL3; Chemokine CCL4; Chemokine CCL5; Chemokines, CC; Chemotaxis; Hip Prosthesis; Humans; Macrophage Inflammatory Proteins; Macrophages; Osteolysis; Prosthesis Failure; Titanium

1999
A prospective review of 303 cementless universal cups with emphasis on wear as the cause of failure.
    Seminars in arthroplasty, 1994, Volume: 5, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Evaluation Studies as Topic; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Polyethylenes; Prospective Studies; Prosthesis Design; Prosthesis Failure; Range of Motion, Articular; Reoperation; Stress, Mechanical; Titanium

1994
SR-PLLA and SR-PGA miniscrews: biodegradation and tissue reactions in the calvarium and dura mater.
    Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery, 1999, Volume: 27, Issue:1

    Topics: Absorbable Implants; Absorption; Animals; Biocompatible Materials; Biodegradation, Environmental; Bone Matrix; Bone Plates; Bone Remodeling; Bone Screws; Follow-Up Studies; Foreign-Body Reaction; Frontal Bone; Hydrolysis; Osteolysis; Osteotomy; Polyesters; Polyglycolic Acid; Radiography; Sheep; Time Factors; Titanium

1999
The role of acetabular component screw holes and/or screws in the development of pelvic osteolysis.
    Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine, 1999, Volume: 213, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Alloys; Bone Screws; Chromium; Cobalt; Follow-Up Studies; Hip Prosthesis; Humans; Incidence; Middle Aged; Osseointegration; Osteolysis; Pelvic Bones; Prosthesis Design; Prosthesis Failure; Radiography; Surface Properties; Titanium

1999
Mechanism of failure in hips with an uncemented, all polyethylene socket.
    Clinical orthopaedics and related research, 1999, Issue:362

    Topics: Acetabulum; Alloys; Arthroplasty, Replacement, Hip; Cementation; Female; Femur; Follow-Up Studies; Foreign Bodies; Hip Prosthesis; Humans; Macrophages; Male; Middle Aged; Osteolysis; Particle Size; Polyethylenes; Prosthesis Design; Prosthesis Failure; Reoperation; Retrospective Studies; Titanium; Treatment Outcome

1999
The acetabular component in total hip arthroplasty. Evaluation of different fixation principles.
    Acta orthopaedica Scandinavica. Supplementum, 1999, Volume: 286

    Topics: Absorbable Implants; Acetabulum; Adult; Aged; Arthroplasty, Replacement, Hip; Biocompatible Materials; Biomechanical Phenomena; Bone Cements; Bone Screws; Calcium Phosphates; Case-Control Studies; Ceramics; Data Interpretation, Statistical; Durapatite; Evaluation Studies as Topic; Female; Follow-Up Studies; Humans; Male; Middle Aged; Orthopedic Fixation Devices; Osteolysis; Prosthesis Design; Prosthesis Failure; Randomized Controlled Trials as Topic; Spectrophotometry, Atomic; Time Factors; Titanium

1999
Migration of polyethylene particles around stable implants in an animal model.
    Journal of long-term effects of medical implants, 1999, Volume: 9, Issue:4

    Topics: Alloys; Animals; Disease Models, Animal; Foreign-Body Migration; Implants, Experimental; Knee Prosthesis; Osteolysis; Particle Size; Polyethylene; Rabbits; Titanium

1999
Tumor necrosis factor-alpha/nuclear transcription factor-kappaB signaling in periprosthetic osteolysis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2000, Volume: 18, Issue:3

    Topics: Animals; Arthroplasty, Replacement; Cell Line; Female; Immunohistochemistry; Macrophages; Male; Mice; Mice, Inbred CBA; NF-kappa B; Osteoclasts; Osteolysis; Signal Transduction; Titanium; Tumor Necrosis Factor-alpha

2000
Osteolysis in cemented titanium alloy hip prosthesis.
    The Journal of arthroplasty, 2000, Volume: 15, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Alloys; Arthroplasty, Replacement, Hip; Female; Follow-Up Studies; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Design; Prosthesis Failure; Reoperation; Survival Analysis; Titanium

2000
Serial measurement of polyethylene wear of well-fixed cementless metal-backed acetabular component in total hip arthroplasty: an over 10 year follow-up study.
    Artificial organs, 2000, Volume: 24, Issue:9

    Topics: Acetabulum; Adult; Aged; Alloys; Analysis of Variance; Arthritis, Rheumatoid; Arthroplasty, Replacement, Hip; Chromium Alloys; Coated Materials, Biocompatible; Femur Head; Femur Head Necrosis; Follow-Up Studies; Hip Joint; Hip Prosthesis; Humans; Image Processing, Computer-Assisted; Middle Aged; Osteoarthritis; Osteolysis; Polyethylene; Prosthesis Design; Prosthesis Failure; Radiography; Risk Factors; Stress, Mechanical; Surface Properties; Time Factors; Titanium

2000
Efficacy of etanercept for wear debris-induced osteolysis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:2

    Topics: Animals; Arthroplasty, Replacement; Cell Line; Culture Media, Conditioned; Enzyme-Linked Immunosorbent Assay; Etanercept; Immunoglobulin G; Interleukin-6; Mice; Mice, Inbred CBA; Osteoclasts; Osteolysis; Receptors, Tumor Necrosis Factor; Titanium; Tumor Necrosis Factor-alpha

2001
The effects of particulate wear debris, cytokines, and growth factors on the functions of MG-63 osteoblasts.
    The Journal of bone and joint surgery. American volume, 2001, Volume: 83, Issue:2

    Topics: Biocompatible Materials; Cell Line; Chromium; Cytokines; Gene Expression Regulation; Growth Substances; Humans; In Vitro Techniques; Joint Prosthesis; Multivariate Analysis; Osteoblasts; Osteolysis; Phagocytosis; Plastics; RNA, Messenger; Titanium

2001
Evidence for a direct role of cyclo-oxygenase 2 in implant wear debris-induced osteolysis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2001, Volume: 16, Issue:4

    Topics: Animals; Bone Resorption; Celecoxib; Cells, Cultured; Crosses, Genetic; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dinoprostone; Female; Interleukin-1; Interleukin-6; Isoenzymes; Macrophage Activation; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Osteoclasts; Osteolysis; Prostaglandin-Endoperoxide Synthases; Prostheses and Implants; Prosthesis Failure; Pyrazoles; Skull; Sulfonamides; Titanium; Tumor Necrosis Factor-alpha

2001
Rapid repair of titanium particle-induced osteolysis is dramatically reduced in aged mice.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2001, Volume: 19, Issue:2

    Topics: Aging; Animals; Female; Mice; Mice, Inbred C57BL; Osteolysis; Parietal Bone; Time Factors; Titanium; Wound Healing

2001
A retrieval study of capital hip prostheses with titanium alloy femoral stems.
    The Journal of bone and joint surgery. British volume, 2001, Volume: 83, Issue:8

    Topics: Aged; Aged, 80 and over; Device Removal; Female; Granulation Tissue; Hip Prosthesis; Humans; Male; Middle Aged; Necrosis; Osteolysis; Reoperation; Titanium

2001
In vivo RANK signaling blockade using the receptor activator of NF-kappaB:Fc effectively prevents and ameliorates wear debris-induced osteolysis via osteoclast depletion without inhibiting osteogenesis.
    Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, 2002, Volume: 17, Issue:2

    Topics: Acid Phosphatase; Animals; Bone Matrix; Bone Remodeling; Bone Resorption; Female; Fluoresceins; Glycoproteins; Mice; Mice, Inbred CBA; Osteoclasts; Osteogenesis; Osteolysis; Osteoprotegerin; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Signal Transduction; Skull; Titanium

2002
Hydroxyapatite-coated stems with metaphyseal and diaphyseal press-fit. Eleven-year follow-up results.
    Acta orthopaedica Belgica, 2002, Volume: 68, Issue:1

    Topics: Aged; Alloys; Arthroplasty, Replacement, Hip; Biocompatible Materials; Biomechanical Phenomena; Durapatite; Female; Follow-Up Studies; Hip; Humans; Male; Middle Aged; Osteolysis; Pain; Postoperative Complications; Prosthesis Design; Survival Analysis; Titanium

2002
Efficacy of ex vivo OPG gene therapy in preventing wear debris induced osteolysis.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 2002, Volume: 20, Issue:2

    Topics: Animals; Animals, Newborn; beta-Galactosidase; Cells, Cultured; Culture Media, Conditioned; Disease Models, Animal; Female; Fibroblasts; Genetic Therapy; Glycoproteins; Lac Operon; Mice; Mice, Inbred CBA; Osteoclasts; Osteolysis; Osteoprotegerin; Prostheses and Implants; Prosthesis Failure; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor; Skull; Titanium; Transduction, Genetic

2002
Clinical experiences with a titanium alloy total hip prosthesis: a posterior approach.
    Clinical orthopaedics and related research, 1979, Issue:144

    Topics: Adult; Aged; Female; Femoral Fractures; Femur Neck; Hepatitis; Hip Dislocation; Hip Joint; Hip Prosthesis; Humans; Leg Length Inequality; Locomotion; Male; Methods; Middle Aged; Movement; Osteolysis; Paralysis; Postoperative Complications; Surgical Wound Infection; Thromboembolism; Titanium

1979
Titanium wear debris in failed cemented total hip arthroplasty. An analysis of 71 cases.
    The Journal of arthroplasty, 1992, Volume: 7, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Cementation; Female; Hip Joint; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Failure; Radiography; Reoperation; Titanium

1992
Aseptic loosening in total hip arthroplasty secondary to osteolysis induced by wear debris from titanium-alloy modular femoral heads.
    The Journal of bone and joint surgery. American volume, 1991, Volume: 73, Issue:3

    Topics: Femur Head; Hip Prosthesis; Humans; Osteolysis; Prosthesis Failure; Titanium

1991
Histologic, biochemical, and ion analysis of tissue and fluids retrieved during total hip arthroplasty.
    Clinical orthopaedics and related research, 1990, Issue:261

    Topics: Aluminum; Dinoprostone; Hip Joint; Hip Prosthesis; Humans; Interleukin-2; Ions; Metals; Microbial Collagenase; Osteolysis; Polyethylenes; Radiography; Titanium; Vanadium

1990
Cementless total joint arthroplasty prostheses with titanium-alloy articular surfaces. A human retrieval analysis.
    Clinical orthopaedics and related research, 1990, Issue:261

    Topics: Adolescent; Adult; Aged; Alloys; Foreign Bodies; Hip Joint; Hip Prosthesis; Humans; Knee Prosthesis; Middle Aged; Osteolysis; Polyethylenes; Titanium

1990
Aseptic loosening in total hip arthroplasty secondary to osteolysis induced by wear debris from titanium-alloy modular femoral heads.
    The Journal of bone and joint surgery. American volume, 1989, Volume: 71, Issue:9

    Topics: Adult; Alloys; Corrosion; Female; Femur Head; Hip Prosthesis; Humans; Male; Middle Aged; Osteolysis; Prosthesis Failure; Radiography; Reoperation; Synovial Membrane; Titanium

1989