tirucallane and Neoplasms

tirucallane has been researched along with Neoplasms* in 2 studies

Other Studies

2 other study(ies) available for tirucallane and Neoplasms

Article	Year
Cytotoxic Activity of Inositol Angelates and Tirucallane-Type Alkaloids from Molecules (Basel, Switzerland), 2020, Mar-09, Volume: 25, Issue:5 Three new inositol angelate compounds ( Topics: Aglaia; Alkaloids; Cell Proliferation; Hep G2 Cells; Humans; Inositol; Neoplasms; Triterpenes	2020
Cytotoxic tirucallane triterpenoids from the stem bark of Melia toosendan. Archives of pharmacal research, 2012, Volume: 35, Issue:11 Three new tirucallane triterpenoids, 3β,16-dihydroxy-25-hydroperoxytirucalla-7,23(24)-dien-6-oxo acid (1), 3β,16β-hydroxytirucalla-7,24(25)-dien-21,23-olide (2), and 3β,16β-hydroxytirucalla-7,24(25)-dien-6-oxo-21,23-olide (3) were isolated from the 70% ethanol extract of the stem bark of Melia toosendan. Their structures were determined on the basis of 1D and 2D NMR (COSY, HMQC, HMBC and NOESY) analyses. The isolated compounds were evaluated in vitro for cytotoxic activities against A549, SK-OV-3, SK-MEL-2 and HCT15 tumor cell lines. Compounds 2 and 3 exhibited significant cytotoxic activities against the four tested cell lines with IC(50) values of 3.4-5.7 μg/mL and 3.2-5.0 μg/mL, respectively. Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Melia; Neoplasms; Plant Bark; Plant Extracts; Plant Stems; Terpenes; Triterpenes	2012

Article

Year

Cytotoxic Activity of Inositol Angelates and Tirucallane-Type Alkaloids from

Molecules (Basel, Switzerland), 2020, Mar-09, Volume: 25, Issue:5

Three new inositol angelate compounds (

Topics: Aglaia; Alkaloids; Cell Proliferation; Hep G2 Cells; Humans; Inositol; Neoplasms; Triterpenes

2020

Cytotoxic tirucallane triterpenoids from the stem bark of Melia toosendan.

Archives of pharmacal research, 2012, Volume: 35, Issue:11

Three new tirucallane triterpenoids, 3β,16-dihydroxy-25-hydroperoxytirucalla-7,23(24)-dien-6-oxo acid (1), 3β,16β-hydroxytirucalla-7,24(25)-dien-21,23-olide (2), and 3β,16β-hydroxytirucalla-7,24(25)-dien-6-oxo-21,23-olide (3) were isolated from the 70% ethanol extract of the stem bark of Melia toosendan. Their structures were determined on the basis of 1D and 2D NMR (COSY, HMQC, HMBC and NOESY) analyses. The isolated compounds were evaluated in vitro for cytotoxic activities against A549, SK-OV-3, SK-MEL-2 and HCT15 tumor cell lines. Compounds 2 and 3 exhibited significant cytotoxic activities against the four tested cell lines with IC(50) values of 3.4-5.7 μg/mL and 3.2-5.0 μg/mL, respectively.

Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Melia; Neoplasms; Plant Bark; Plant Extracts; Plant Stems; Terpenes; Triterpenes

2012