tirucallane has been researched along with Adenocarcinoma-of-Lung* in 1 studies
1 other study(ies) available for tirucallane and Adenocarcinoma-of-Lung
| Article | Year |
|---|---|
Cytotoxic tirucallane triterpenoids from Melia azedarach fruits.
The phytochemical investigation of the dichloromethane-soluble part of the methanol extract obtained from the fruits of Melia azedarach afforded one new tirucallane-type triterpene, 3-alpha-tigloylmelianol and three known tirucallanes, melianone, 21-beta-acetoxy-melianone, and methyl kulonate. The structure of the isolated compounds was mainly determined by 1D and 2D NMR experiments as well as HPLC-Q-TOF mass spectrometry. The cytotoxicity of the isolated compounds toward the human lung adenocarcinoma epithelial cell line A549 was determined, while no activity was observed against the phytonematode Meloidogyne incognita. Topics: Adenocarcinoma; Adenocarcinoma of Lung; Animals; Cell Line, Tumor; Cytotoxins; Epithelial Cells; Fruit; Humans; Lung Neoplasms; Melia azedarach; Molecular Structure; Plant Extracts; Triterpenes; Tylenchoidea | 2010 |