Page last updated: 2024-09-04

tipifarnib and Neurofibroma, Plexiform

tipifarnib has been researched along with Neurofibroma, Plexiform in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (50.00)29.6817
2010's2 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Balis, FM; Belasco, J; Dombi, E; Fox, E; Gillespie, A; Goldman, S; Kieran, MW; Kim, A; Korf, BR; Martin, S; Patronas, N; Perentesis, JP; Reddy, A; Salzer, W; Solomon, J; Steinberg, SM; Widemann, BC; Wolters, PL; Wright, JJ1
Prados, MD1
Arceci, RJ; Balis, FM; Blaney, SM; End, D; Fox, E; Gillespie, A; Jayaprakash, N; Palumbo, JS; Pitney, A; Salzer, WL; Whitcomb, P; Widemann, BC; Zannikos, P1
Bouffet, E; Drake, JM; Parkin, P; Rutka, JT; Serletis, D; Shroff, M1

Trials

2 trial(s) available for tipifarnib and Neurofibroma, Plexiform

ArticleYear
Phase 2 randomized, flexible crossover, double-blinded, placebo-controlled trial of the farnesyltransferase inhibitor tipifarnib in children and young adults with neurofibromatosis type 1 and progressive plexiform neurofibromas.
    Neuro-oncology, 2014, Volume: 16, Issue:5

    Topics: Adolescent; Adult; Antineoplastic Agents; Child; Child, Preschool; Cross-Over Studies; Disease Progression; Double-Blind Method; Enzyme Inhibitors; Farnesyltranstransferase; Female; Humans; Male; Neurofibroma, Plexiform; Neurofibromatosis 1; Quinolones; Treatment Outcome; Young Adult

2014
Phase I trial and pharmacokinetic study of the farnesyltransferase inhibitor tipifarnib in children with refractory solid tumors or neurofibromatosis type I and plexiform neurofibromas.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Jan-20, Volume: 24, Issue:3

    Topics: Adolescent; Antineoplastic Agents; Bone Marrow; Child; Child, Preschool; Drug Administration Schedule; Drug Eruptions; Enzyme Inhibitors; Farnesyltranstransferase; Female; Gastrointestinal Tract; Humans; Male; Neurofibroma, Plexiform; Neurofibromatosis 1; Quinolones; Treatment Outcome

2006

Other Studies

2 other study(ies) available for tipifarnib and Neurofibroma, Plexiform

ArticleYear
Plexiform neurofibromas, trial design, and the definitions of "progression" and "treatment failure".
    Neuro-oncology, 2014, Volume: 16, Issue:5

    Topics: Antineoplastic Agents; Enzyme Inhibitors; Farnesyltranstransferase; Female; Humans; Male; Neurofibroma, Plexiform; Neurofibromatosis 1; Quinolones

2014
Massive plexiform neurofibromas in childhood: natural history and management issues.
    Journal of neurosurgery, 2007, Volume: 106, Issue:5 Suppl

    Topics: Adolescent; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Child; Child, Preschool; Cyclophosphamide; Humans; Magnetic Resonance Imaging; Male; Neoplasms, Second Primary; Neurofibroma, Plexiform; Neurosurgical Procedures; Pain; Quinolones; Respiration Disorders; Retrospective Studies

2007