Page last updated: 2024-09-04

tipifarnib and Melanoma

tipifarnib has been researched along with Melanoma in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bentke, A; Krzykowska-Petitjean, K; Laidler, P; MaƂecki, J; Ostrowska, B1
Akerley, WL; Flaherty, LE; Kirkwood, JM; Lao, CD; Margolin, KA; Moon, J; Othus, M; Sondak, VK; Sosman, JA1
Blaskovich, MA; Bucher, C; Gajewski, TF; Haluska, F; Johnson, J; Linette, G; Niedzwiecki, D; Salama, AK; Sebti, SM1

Trials

2 trial(s) available for tipifarnib and Melanoma

ArticleYear
Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Feb-15, Volume: 18, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Quinolones; Sirolimus; Sorafenib; Survival Analysis; Treatment Outcome

2012
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
    Journal of translational medicine, 2012, Dec-10, Volume: 10

    Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cell Line, Tumor; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Female; HSP40 Heat-Shock Proteins; Humans; Interferon-gamma; Male; Melanoma; Middle Aged; Neoplasm Staging; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Treatment Outcome

2012

Other Studies

1 other study(ies) available for tipifarnib and Melanoma

ArticleYear
Tanespimycin and tipifarnib exhibit synergism in inducing apoptosis in melanoma cell lines from later stages of tumor progression.
    Cancer investigation, 2013, Volume: 31, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Melanoma; Protein Serine-Threonine Kinases; Quinolones

2013