tipifarnib has been researched along with Melanoma in 3 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 3 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Bentke, A; Krzykowska-Petitjean, K; Laidler, P; MaĆecki, J; Ostrowska, B | 1 |
Akerley, WL; Flaherty, LE; Kirkwood, JM; Lao, CD; Margolin, KA; Moon, J; Othus, M; Sondak, VK; Sosman, JA | 1 |
Blaskovich, MA; Bucher, C; Gajewski, TF; Haluska, F; Johnson, J; Linette, G; Niedzwiecki, D; Salama, AK; Sebti, SM | 1 |
2 trial(s) available for tipifarnib and Melanoma
Article | Year |
---|---|
Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Quinolones; Sirolimus; Sorafenib; Survival Analysis; Treatment Outcome | 2012 |
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).
Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cell Line, Tumor; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Female; HSP40 Heat-Shock Proteins; Humans; Interferon-gamma; Male; Melanoma; Middle Aged; Neoplasm Staging; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Treatment Outcome | 2012 |
1 other study(ies) available for tipifarnib and Melanoma
Article | Year |
---|---|
Tanespimycin and tipifarnib exhibit synergism in inducing apoptosis in melanoma cell lines from later stages of tumor progression.
Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Melanoma; Protein Serine-Threonine Kinases; Quinolones | 2013 |