Page last updated: 2024-09-04

tipifarnib and Malignant Melanoma

tipifarnib has been researched along with Malignant Melanoma in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	3 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bentke, A; Krzykowska-Petitjean, K; Laidler, P; Małecki, J; Ostrowska, B	1
Akerley, WL; Flaherty, LE; Kirkwood, JM; Lao, CD; Margolin, KA; Moon, J; Othus, M; Sondak, VK; Sosman, JA	1
Blaskovich, MA; Bucher, C; Gajewski, TF; Haluska, F; Johnson, J; Linette, G; Niedzwiecki, D; Salama, AK; Sebti, SM	1

Trials

2 trial(s) available for tipifarnib and Malignant Melanoma

Article	Year
Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438). Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Feb-15, Volume: 18, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Quinolones; Sirolimus; Sorafenib; Survival Analysis; Treatment Outcome	2012
Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104). Journal of translational medicine, 2012, Dec-10, Volume: 10 Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cell Line, Tumor; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Female; HSP40 Heat-Shock Proteins; Humans; Interferon-gamma; Male; Melanoma; Middle Aged; Neoplasm Staging; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Treatment Outcome	2012

Article

Year

Randomized phase II trial of sorafenib with temsirolimus or tipifarnib in untreated metastatic melanoma (S0438).

Clinical cancer research : an official journal of the American Association for Cancer Research, 2012, Feb-15, Volume: 18, Issue:4

Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Female; Humans; Male; Melanoma; Middle Aged; Neoplasm Metastasis; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Pyridines; Quinolones; Sirolimus; Sorafenib; Survival Analysis; Treatment Outcome

2012

Phase II study of the farnesyltransferase inhibitor R115777 in advanced melanoma (CALGB 500104).

Journal of translational medicine, 2012, Dec-10, Volume: 10

Topics: Adult; Aged; Aged, 80 and over; Biopsy; Cell Line, Tumor; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Farnesyltranstransferase; Female; HSP40 Heat-Shock Proteins; Humans; Interferon-gamma; Male; Melanoma; Middle Aged; Neoplasm Staging; Phosphorylation; Proto-Oncogene Proteins c-akt; Quinolones; Signal Transduction; Skin Neoplasms; T-Lymphocytes; Treatment Outcome

2012

Other Studies

1 other study(ies) available for tipifarnib and Malignant Melanoma

Article	Year
Tanespimycin and tipifarnib exhibit synergism in inducing apoptosis in melanoma cell lines from later stages of tumor progression. Cancer investigation, 2013, Volume: 31, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Melanoma; Protein Serine-Threonine Kinases; Quinolones	2013

Article

Year

Tanespimycin and tipifarnib exhibit synergism in inducing apoptosis in melanoma cell lines from later stages of tumor progression.

Cancer investigation, 2013, Volume: 31, Issue:8

Topics: Antineoplastic Agents; Apoptosis; Benzoquinones; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Proliferation; Drug Resistance, Neoplasm; Drug Synergism; Enzyme Activation; HSP90 Heat-Shock Proteins; Humans; Lactams, Macrocyclic; Melanoma; Protein Serine-Threonine Kinases; Quinolones

2013