Page last updated: 2024-09-04

tipifarnib and Colorectal Cancer

tipifarnib has been researched along with Colorectal Cancer in 4 studies

Research

Studies (4)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andre, T; Belly, R; Cunningham, D; de Gramont, A; Dostalova, J; Humblet, Y; Illes, A; Iveson, T; Kourteva, G; Palmer, PA; Park, YC; Perez-Ruixo, JJ; Rao, S; Scheithauer, W; Smakal, M	1
Abbruzzese, JL; Dakhil, SR; Lenz, HJ; Macdonald, JS; McCoy, S; Neubauer, MA; Rivkin, SE; Tanaka, MS; Whitehead, RP	1
Chen, W; Chow, A; Hayes, S; Perez-Ruixo, JJ; Zhang, S	1
Barrie, E; Kelland, LR; Rowlands, MG; Smith, V; Workman, P	1

Trials

3 trial(s) available for tipifarnib and Colorectal Cancer

Article	Year
Phase III double-blind placebo-controlled study of farnesyl transferase inhibitor R115777 in patients with refractory advanced colorectal cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2004, Oct-01, Volume: 22, Issue:19 Topics: Adult; Aged; Alkyl and Aryl Transferases; Antineoplastic Agents; Colorectal Neoplasms; Double-Blind Method; Farnesyltranstransferase; Female; Humans; Male; Middle Aged; Placebos; Quinolones; Survival Rate	2004
Phase II trial of R115777 (NSC #70818) in patients with advanced colorectal cancer: a Southwest Oncology Group study. Investigational new drugs, 2006, Volume: 24, Issue:4 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Male; Middle Aged; Neoplasm Staging; Quinolones; Southwestern United States; Survival Analysis	2006
Exposure-toxicity relationships for tipifarnib in cancer patients. British journal of clinical pharmacology, 2007, Volume: 64, Issue:2 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Colorectal Neoplasms; Dose-Response Relationship, Drug; Female; Humans; Leukemia; Male; Middle Aged; Quinolones; Treatment Outcome	2007

Other Studies

1 other study(ies) available for tipifarnib and Colorectal Cancer

Article	Year
Establishment and characterization of acquired resistance to the farnesyl protein transferase inhibitor R115777 in a human colon cancer cell line. Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:6 Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Blotting, Western; Cell Division; Chromones; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Farnesyltranstransferase; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinazolines; Quinolones; Transfection; Tumor Cells, Cultured	2002

Article

Year

Establishment and characterization of acquired resistance to the farnesyl protein transferase inhibitor R115777 in a human colon cancer cell line.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2002, Volume: 8, Issue:6

Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Blotting, Western; Cell Division; Chromones; Colorectal Neoplasms; Drug Resistance, Neoplasm; ErbB Receptors; Farnesyltranstransferase; Humans; Morpholines; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Phosphorylation; Quinazolines; Quinolones; Transfection; Tumor Cells, Cultured

2002