Page last updated: 2024-09-04

tipifarnib and Brain Neoplasms

tipifarnib has been researched along with Brain Neoplasms in 10 studies

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (50.00)29.6817
2010's5 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Abrey, LE; Aldape, K; Chang, S; Cloughesy, TF; Dancey, JE; DeAngelis, LM; Drappatz, J; Ebiana, VA; Gilbert, M; Kuhn, J; Levin, VA; Lieberman, F; Mehta, MP; Nghiemphu, PL; Prados, M; Robins, HI; Wen, P; Wright, JJ; Yung, WKA1
Benouaich-Amiel, A; Cohen-Jonathan Moyal, E; De Porre, P; Delisle, MB; Ducassou, A; Favre, G; Filleron, T; Ken, S; Laprie, A; Lubrano, V; Poublanc, M; Sol, JC; Toulas, C; Uro-Coste, E; Verrelle, P1
Berry, I; Catalaa, I; Celsis, P; Cohen-Jonathan Moyal, E; Deviers, A; Filleron, T; Ken, S; Laprie, A; Laruelo, A; Lubrano, V; Mogicato, G; Rowland, B1
Berry, I; Catalaa, I; Celsis, P; Deviers, A; Filleron, T; Ken, S; Khalifa, J; Laprie, A; Lotterie, JA; Lubrano, V; Moyal, EC; Péran, P1
Desideri, S; Fisher, J; Grossman, S; Lesser, G; Lustig, R; Mikkelsen, T; Wright, J; Ye, X1
Abrey, L; Chang, SM; Cloughesy, TF; DeAngelis, LM; Demopoulos, A; Drappatz, J; Fine, HA; Fink, K; Kesari, S; Lamborn, KR; Lassman, AB; Lieberman, FS; Malkin, MG; Mehta, MP; Nghiemphu, PL; Prados, MD; Robins, HI; Torres-Trejo, A; Wen, PY1
Abrey, L; Chang, S; Cloughesy, TF; DeAngelis, L; Fink, K; Groves, M; Junck, L; Kuhn, J; Lamborn, K; Lieberman, FS; Mehta, M; Paquette, S; Prados, M; Robins, HI; Schiff, D; Sebti, SM; Wen, P; Wright, J; Yung, A1
Abrey, L; Aldape, K; Chang, SM; Cloughesy, TF; DeAngelis, LM; Fink, KL; Gilbert, MR; Groves, MD; Junck, L; Kuhn, J; Lamborn, KR; Lieberman, F; Mehta, M; Prados, MD; Raizer, JJ; Robins, HI; Schiff, D; Wen, PY; Wright, J; Yung, WK1
Alaux, B; Berchery, D; Bousquet, P; Catalaa, I; Dalenc, F; De Porre, P; Delannes, M; Laprie, A; Moyal, EC; Poublanc, M; Sabatier, J; Toulas, C1
Cohen, K; Fouladi, M; Helton, KJ; Holmes, E; Laningham, F; Nicholson, HS; Pollack, IF; Speights, RA; Wright, J; Zhou, T1

Trials

10 trial(s) available for tipifarnib and Brain Neoplasms

ArticleYear
Phase I study of sorafenib and tipifarnib for recurrent glioblastoma: NABTC 05-02.
    Journal of neuro-oncology, 2018, Volume: 136, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Quinolones; Sorafenib; Treatment Outcome

2018
αvβ3 Integrin and Fibroblast growth factor receptor 1 (FGFR1): Prognostic factors in a phase I-II clinical trial associating continuous administration of Tipifarnib with radiotherapy for patients with newly diagnosed glioblastoma.
    European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:9

    Topics: Adult; Aged; Antineoplastic Agents; Biomarkers; Brain Neoplasms; Combined Modality Therapy; Drug Administration Schedule; Female; Fibroblast Growth Factor 2; Focal Adhesion Kinase 1; Glioblastoma; Humans; Integrin alphaVbeta3; Male; Middle Aged; Protein Serine-Threonine Kinases; Quinolones; Radiation-Sensitizing Agents; Receptor, Fibroblast Growth Factor, Type 1; Receptors, Vitronectin; Treatment Outcome

2013
Evaluation of the lactate-to-N-acetyl-aspartate ratio defined with magnetic resonance spectroscopic imaging before radiation therapy as a new predictive marker of the site of relapse in patients with glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2014, Oct-01, Volume: 90, Issue:2

    Topics: Adult; Aged; Antineoplastic Agents; Aspartic Acid; Biomarkers, Tumor; Brain Neoplasms; Choline; Creatine; Female; Glioblastoma; Humans; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Quinolones; Radiotherapy, Conformal; Sensitivity and Specificity

2014
Voxel-based evidence of perfusion normalization in glioblastoma patients included in a phase I-II trial of radiotherapy/tipifarnib combination.
    Journal of neuro-oncology, 2015, Volume: 124, Issue:3

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Cerebrovascular Circulation; Contrast Media; Female; Follow-Up Studies; Glioblastoma; Humans; Image Processing, Computer-Assisted; Magnetic Resonance Imaging; Male; Middle Aged; Quinolones; Radiotherapy; Survival Analysis; Treatment Outcome

2015
Phase II preradiation R115777 (tipifarnib) in newly diagnosed GBM with residual enhancing disease.
    Neuro-oncology, 2008, Volume: 10, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm, Residual; Neurosurgical Procedures; Quinolones; Radiotherapy

2008
A phase I trial of tipifarnib with radiation therapy, with and without temozolomide, for patients with newly diagnosed glioblastoma.
    International journal of radiation oncology, biology, physics, 2011, Dec-01, Volume: 81, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemoradiotherapy; Dacarbazine; Female; Glioblastoma; Humans; Male; Middle Aged; Quinolones; Temozolomide

2011
Phase I trial of tipifarnib in patients with recurrent malignant glioma taking enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2005, Sep-20, Volume: 23, Issue:27

    Topics: Administration, Oral; Adult; Aged; Anticonvulsants; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Glioma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Quinolones; Risk Assessment; Salvage Therapy; Survival Analysis; Treatment Outcome

2005
Phase II trial of tipifarnib in patients with recurrent malignant glioma either receiving or not receiving enzyme-inducing antiepileptic drugs: a North American Brain Tumor Consortium Study.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2006, Aug-01, Volume: 24, Issue:22

    Topics: Adult; Aged; Anticonvulsants; Antineoplastic Agents; Brain Neoplasms; Disease-Free Survival; Drug Administration Schedule; Enzyme Induction; Epilepsy; Female; Glioblastoma; Glioma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; North America; Quinolones; Treatment Outcome

2006
Phase I trial of tipifarnib (R115777) concurrent with radiotherapy in patients with glioblastoma multiforme.
    International journal of radiation oncology, biology, physics, 2007, Aug-01, Volume: 68, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Female; Glioblastoma; Humans; Male; Maximum Tolerated Dose; Middle Aged; Quinolones; Radiation Pneumonitis; Radiotherapy Dosage; Radiotherapy, Conformal

2007
A phase II study of the farnesyl transferase inhibitor, tipifarnib, in children with recurrent or progressive high-grade glioma, medulloblastoma/primitive neuroectodermal tumor, or brainstem glioma: a Children's Oncology Group study.
    Cancer, 2007, Dec-01, Volume: 110, Issue:11

    Topics: Adolescent; Adult; Antineoplastic Agents; Brain Neoplasms; Brain Stem Neoplasms; Child; Child, Preschool; Disease Progression; Female; Glioma; Humans; Male; Medulloblastoma; Neuroectodermal Tumors; Quinolones; Treatment Outcome

2007