Page last updated: 2024-09-04

tipifarnib and Acute Disease

tipifarnib has been researched along with Acute Disease in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's7 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Atkins, D; Belly, RT; Karp, JE; Lancet, JE; Raponi, M; Wang, Y1
Zhang, GS1
Feldman, EJ1
Grever, MR1
Sekeres, MA1
De Porre, P; Fenaux, P; Harousseau, JL; Huguet, F; Lancet, JE; Lowenberg, B; Rackoff, W; Reiffers, J; Stone, R; Thomas, X; Zhang, S1

Reviews

3 review(s) available for tipifarnib and Acute Disease

ArticleYear
Farnesyltransferase inhibitors in myelodysplastic syndrome.
    Current hematology reports, 2005, Volume: 4, Issue:3

    Topics: Acute Disease; Aged; Alkyl and Aryl Transferases; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Disease Progression; Enzyme Inhibitors; Farnesyltranstransferase; Genes, ras; Hematologic Neoplasms; Humans; Leukemia, Myeloid; Middle Aged; Myelodysplastic Syndromes; Piperidines; Protein Prenylation; Protein Processing, Post-Translational; Proto-Oncogene Proteins p21(ras); Pyridines; Quinolones; Remission Induction; Signal Transduction; Treatment Outcome

2005
New drugs in acute myeloid leukemia.
    Clinical advances in hematology & oncology : H&O, 2003, Volume: 1, Issue:8

    Topics: Acute Disease; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; Drug Evaluation; Gene Expression Regulation, Neoplastic; Genes, bcl-2; Humans; Imatinib Mesylate; Leukemia, Myeloid; Piperazines; Protein-Tyrosine Kinases; Pyrimidines; Quinolones; Thionucleotides

2003
Non-transplant therapy for older adults with acute myeloid leukemia.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2006, Volume: 4, Issue:1

    Topics: Acute Disease; Age Factors; Aged; Aminoglycosides; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cytarabine; Cytogenetic Analysis; Gemtuzumab; Humans; Leukemia, Myeloid; Quinolones

2006

Trials

1 trial(s) available for tipifarnib and Acute Disease

ArticleYear
A phase 2 study of the oral farnesyltransferase inhibitor tipifarnib in patients with refractory or relapsed acute myeloid leukemia.
    Blood, 2007, Jun-15, Volume: 109, Issue:12

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Blast Crisis; Bone Marrow Cells; Farnesyltranstransferase; Female; Humans; Leukemia, Myeloid; Male; Middle Aged; Quinolones; Remission Induction; Salvage Therapy; Survival Rate; Treatment Outcome

2007

Other Studies

3 other study(ies) available for tipifarnib and Acute Disease

ArticleYear
Microarray analysis reveals genetic pathways modulated by tipifarnib in acute myeloid leukemia.
    BMC cancer, 2004, Aug-25, Volume: 4

    Topics: Acute Disease; Alkyl and Aryl Transferases; Apoptosis; Cell Growth Processes; Farnesyltranstransferase; Gene Expression Regulation, Leukemic; HL-60 Cells; Humans; Leukemia, Myeloid; Oligonucleotide Array Sequence Analysis; Quinolones

2004
[New targets for molecular therapy of acute leukemia: a "single-hit" or "multiple-hit" strategy against signaling pathway].
    Zhonghua yi xue za zhi, 2005, Feb-23, Volume: 85, Issue:7

    Topics: Acute Disease; Antineoplastic Agents; Carbazoles; Furans; Humans; Indoles; Leukemia; Leukemia, Myeloid, Acute; Mutation; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein-Tyrosine Kinases; Quinolones; ras Proteins; Staurosporine

2005
Molecule of the month. Tipifarnib.
    Drug news & perspectives, 2005, Volume: 18, Issue:3

    Topics: Acute Disease; Aged; Antineoplastic Agents; Clinical Trials as Topic; Humans; Leukemia, Myeloid; Quinolones

2005