tiopronin has been researched along with Urinary Calculi in 25 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
Urinary Calculi: Low-density crystals or stones in any part of the URINARY TRACT. Their chemical compositions often include CALCIUM OXALATE, magnesium ammonium phosphate (struvite), CYSTINE, or URIC ACID.
| Excerpt | Relevance | Reference |
|---|---|---|
| "From 1987 to 1990, 719 subjects (385 males and 334 females) were screened, by means of urocystin-kit, for cystinuria and cystine lithiasis, in Epirus district (North-West Greece)." | 7.69 | [Results of treatment of cystinuria and cystine lithiasis with alpha-mercaptopropionylglycine. Apropos of 40 patients]. ( Chambilomatis, P; Evangelou, A; Giannakis, D; Giannakopoulos, X; Kalfakakou, V; Kallistratos, G; Karkabounas, S; Tsoumanis, P, 1994) |
| " Drug dosage was adjusted to maintain free urine cystine level below 100 micromol/mmol creatinine." | 6.73 | Cystinuria in children and young adults: success of monitoring free-cystine urine levels. ( Dello Strologo, L; Laurenzi, C; Legato, A; Pastore, A, 2007) |
| "Fifty-two cystinuric patients (cystine SF) entering our programme since 1970 were compared with 3215 SF without cystinuria (routine SF), of whom 114 had a single functioning kidney (routine SF + nephrectomy)." | 3.73 | Reduced renal function and benefits of treatment in cystinuria vs other forms of nephrolithiasis. ( Coe, FL; Evan, AP; Parks, JH; Worcester, EM, 2006) |
| " To improve the medical treatment of patients with cystinuria, this strategy was performed to guide the fluid intake and the administration of SH compounds (tiopronin, D-penicillamine, and MESNA)." | 3.71 | Cystine analyses of separate day and night urine as a basis for the management of patients with homozygous cystinuria. ( Christensson, A; Denneberg, T; Fjellstedt, E; Jeppsson, JO; Tiselius, HG, 2001) |
| "From 1987 to 1990, 719 subjects (385 males and 334 females) were screened, by means of urocystin-kit, for cystinuria and cystine lithiasis, in Epirus district (North-West Greece)." | 3.69 | [Results of treatment of cystinuria and cystine lithiasis with alpha-mercaptopropionylglycine. Apropos of 40 patients]. ( Chambilomatis, P; Evangelou, A; Giannakis, D; Giannakopoulos, X; Kalfakakou, V; Kallistratos, G; Karkabounas, S; Tsoumanis, P, 1994) |
| "During a 4-year period 9 cases of severe recurrent cystine stones and cystinuria were treated with mercaptopropionylglycine." | 3.65 | Mercaptopropionylglycine: a progress in cystine stone therapy. ( Hautmann, R; Lutzeyer, W; Stuhlsatz, HW; Terhorst, B, 1977) |
| " Drug dosage was adjusted to maintain free urine cystine level below 100 micromol/mmol creatinine." | 2.73 | Cystinuria in children and young adults: success of monitoring free-cystine urine levels. ( Dello Strologo, L; Laurenzi, C; Legato, A; Pastore, A, 2007) |
| "Captopril was added for failure of or intolerance to D-penicillamine or alpha-mercaptopropionylglycine." | 2.68 | Medical treatment of cystinuria: results of contemporary clinical practice. ( Chow, GK; Streem, SB, 1996) |
| "The potassium citrate dose was adjusted to render urinary pH 6." | 1.31 | Cystine calculi in children: the results of a metabolic evaluation and response to medical therapy. ( Atsu, N; Bakkaloglu, M; Sahin, A; Tekgul, S; Tekin, A, 2001) |
| "Cystinuria is an autosomal recessive disorder, and primary manifestation is the repeated formation of cystine calculi." | 1.30 | [Clinical study on cystinuria in children--the stone management and the prevention of calculi recurrence]. ( Asanuma, H; Kawamura, T; Nagakura, K; Nakai, H; Shishido, S; Takeda, M; Yamafuji, M, 1998) |
| " We concluded that 2-MPG is well tolerated and promising for treatment of cystinuric dogs, but the pharmacokinetic studies should be expanded to include different dosage regimens, and results of long-term treatment should be evaluated." | 1.27 | Treatment of clinically normal and cystinuric dogs with 2-mercaptopropionylglycine. ( Denneberg, T; Hoppe, A; Kågedal, B, 1988) |
| " A relatively high dosage resulted in a reduction of the cytinuria." | 1.25 | [Cystine stone therapy with mercapto-propyonyl-glycine (MPG) (Thiola) (author's transl)]. ( Stuhlsatz, HW; Terhorst, B, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 6 (24.00) | 18.2507 |
| 2000's | 4 (16.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Worcester, EM | 1 |
| Coe, FL | 1 |
| Evan, AP | 1 |
| Parks, JH | 1 |
| Dello Strologo, L | 1 |
| Laurenzi, C | 1 |
| Legato, A | 1 |
| Pastore, A | 1 |
| Berio, A | 1 |
| Laurenti, C | 1 |
| De Dominicis, C | 1 |
| Gallucci, M | 2 |
| Iori, F | 1 |
| Dal Forno, S | 1 |
| Franco, G | 1 |
| Denneberg, T | 3 |
| Jeppsson, JO | 2 |
| Stenberg, P | 1 |
| Johansen, K | 1 |
| Gammelgård, PA | 1 |
| Jørgensen, FS | 1 |
| Dimopoulos, C | 1 |
| Stokidis, D | 1 |
| Kallistratos, G | 3 |
| Sidéris, C | 1 |
| Kyriakidis, A | 1 |
| Kollias, G | 1 |
| Giannakopoulos, X | 1 |
| Kalfakakou, V | 1 |
| Tsoumanis, P | 1 |
| Karkabounas, S | 1 |
| Giannakis, D | 1 |
| Chambilomatis, P | 1 |
| Evangelou, A | 1 |
| Chow, GK | 1 |
| Streem, SB | 1 |
| Oner, A | 1 |
| Demircin, G | 1 |
| Ipekçioğlu, H | 1 |
| Bülbül, M | 1 |
| Ecin, N | 1 |
| Owada, M | 1 |
| Watanabe, S | 1 |
| Tsuda, M | 1 |
| Asanuma, H | 1 |
| Nakai, H | 1 |
| Takeda, M | 1 |
| Shishido, S | 1 |
| Kawamura, T | 1 |
| Nagakura, K | 1 |
| Yamafuji, M | 1 |
| Akakura, K | 1 |
| Egoshi, K | 1 |
| Ueda, T | 1 |
| Nozumi, K | 1 |
| Kotake, T | 1 |
| Masai, M | 1 |
| Ito, H | 1 |
| Tekin, A | 1 |
| Tekgul, S | 1 |
| Atsu, N | 1 |
| Sahin, A | 1 |
| Bakkaloglu, M | 1 |
| Fjellstedt, E | 1 |
| Christensson, A | 1 |
| Tiselius, HG | 1 |
| Perfumo, F | 1 |
| Basile, G | 1 |
| Ginevri, F | 1 |
| Gusmano, R | 1 |
| Miano, L | 1 |
| Petta, S | 1 |
| Barbero, S | 1 |
| Domeneghetti, G | 1 |
| Sardi, R | 1 |
| Terhorst, B | 2 |
| Stuhlsatz, HW | 2 |
| Hautmann, R | 1 |
| Lutzeyer, W | 1 |
| Carratù, A | 1 |
| Innocenti, MG | 1 |
| Rossi, R | 1 |
| Remien, A | 1 |
| Burchardt, P | 1 |
| Hoppe, A | 1 |
| Kågedal, B | 1 |
| Grunfeld Avellan, JA | 1 |
2 reviews available for tiopronin and Urinary Calculi
| Article | Year |
|---|---|
[Cystinuria].
Topics: Amino Acid Transport Systems, Basic; Carrier Proteins; Citric Acid; Cystinuria; Diagnosis, Different | 1998 |
[The hyperaminoacidurias with special reference to cystinuria].
Topics: Amino Acids; Biological Transport; Carrier Proteins; Child; Cystinuria; Female; Humans; Microvilli; | 1979 |
2 trials available for tiopronin and Urinary Calculi
| Article | Year |
|---|---|
Cystinuria in children and young adults: success of monitoring free-cystine urine levels.
Topics: Adolescent; Adult; Alkalies; Chelating Agents; Child; Child, Preschool; Cystine; Cystinuria; Diureti | 2007 |
Medical treatment of cystinuria: results of contemporary clinical practice.
Topics: Adolescent; Adult; Angiotensin-Converting Enzyme Inhibitors; Captopril; Child; Child, Preschool; Cys | 1996 |
21 other studies available for tiopronin and Urinary Calculi
| Article | Year |
|---|---|
Reduced renal function and benefits of treatment in cystinuria vs other forms of nephrolithiasis.
Topics: Adult; Chelating Agents; Cystine; Cystinuria; Drinking; Female; Humans; Male; Middle Aged; Nephrecto | 2006 |
[Prevention of cysteine calculosis by the continuous administration of alpha-mercaptopropionylglycine].
Topics: Adolescent; Amino Acids, Sulfur; Cysteine; Electrophoresis; Humans; Lysine; Male; Renal Aminoaciduri | 1983 |
[Medical treatment of cystine lithiasis in children].
Topics: Amino Acids, Sulfur; Child; Cystine; Female; Humans; Male; Penicillamine; Recurrence; Tiopronin; Uri | 1984 |
Alternative treatment of cystinuria with alpha-merkaptopropionylglycine, Thiola.
Topics: Adolescent; Adult; Aged; Amino Acids, Sulfur; Cystine; Cystinuria; Dipeptides; Female; Humans; Male; | 1983 |
Treatment of cystinuria with alpha-mercaptopropionylglycine.
Topics: Adult; Amino Acids, Sulfur; Cystine; Cystinuria; Female; Humans; Male; Recurrence; Tiopronin; Urinar | 1980 |
[The use of mercapto-propionyl-glycine in the treatment of cystine lithiasis (author's transl)].
Topics: Adult; Amino Acids, Sulfur; Cystinuria; Female; Humans; Kidney Calculi; Male; Recurrence; Tiopronin; | 1981 |
[Results of treatment of cystinuria and cystine lithiasis with alpha-mercaptopropionylglycine. Apropos of 40 patients].
Topics: Adult; Aged; Cystine; Cystinuria; Female; Follow-Up Studies; Humans; Male; Middle Aged; Recurrence; | 1994 |
Etiological and clinical patterns of urolithiasis in Turkish children.
Topics: Adolescent; Age Factors; Anti-Bacterial Agents; Bacteriuria; Benzothiadiazines; Child; Child, Presch | 1997 |
[Clinical study on cystinuria in children--the stone management and the prevention of calculi recurrence].
Topics: Adolescent; Adult; Child; Child, Preschool; Cystinuria; Female; Follow-Up Studies; Humans; Infant; L | 1998 |
The long-term outcome of cystinuria in Japan.
Topics: Adult; Chelating Agents; Cystine; Cystinuria; Female; Follow-Up Studies; Humans; Hydrogen-Ion Concen | 1998 |
Cystine calculi in children: the results of a metabolic evaluation and response to medical therapy.
Topics: Adolescent; Child; Child, Preschool; Cysteine; Female; Humans; Infant; Lithotripsy; Male; Potassium | 2001 |
Cystine analyses of separate day and night urine as a basis for the management of patients with homozygous cystinuria.
Topics: Adult; Aged; Circadian Rhythm; Cystinuria; Dose-Response Relationship, Drug; Female; Homozygote; Hum | 2001 |
Results of medical treatment of cystine lithiasis.
Topics: Adult; Cystine; Female; Humans; Male; Middle Aged; Tiopronin; Urinary Calculi | 1979 |
[Cystinuria. Description of a case].
Topics: Child, Preschool; Cystinuria; Female; Humans; Tiopronin; Urinary Calculi | 1979 |
[Cystine stone therapy with mercapto-propyonyl-glycine (MPG) (Thiola) (author's transl)].
Topics: Adult; Amino Acids; Amino Acids, Sulfur; Cystinuria; Drug Tolerance; Female; Humans; Long-Term Care; | 1975 |
Mercaptopropionylglycine: a progress in cystine stone therapy.
Topics: Adult; Amino Acids, Sulfur; Cystine; Cystinuria; Female; Follow-Up Studies; Humans; Male; Penicillam | 1977 |
[Cystine lithiasis. Report of a case with severe neuro-psychic disturbances. Discussion of the effects of anti-lithiasic treatment].
Topics: Amino Acids, Sulfur; Child; Cystinuria; Epilepsy; Humans; Male; Mental Disorders; Tiopronin; Urinary | 1976 |
Treatment of cystinuria with Thiola (alpha-mercaptopropionyl glycine).
Topics: Amino Acids, Sulfur; Cystinuria; Dose-Response Relationship, Drug; Female; Humans; Male; Recurrence; | 1975 |
Tiopronin for cystinuria.
Topics: Cystine; Cystinuria; Gastrointestinal Diseases; Humans; Leukopenia; Solubility; Tiopronin; Urinary C | 1989 |
Treatment of clinically normal and cystinuric dogs with 2-mercaptopropionylglycine.
Topics: Administration, Oral; Amino Acids, Sulfur; Animals; Cystinuria; Dog Diseases; Dogs; Drug Tolerance; | 1988 |
[Cystine lithiasis in the adult. Apropos of an isolated case without familial antecedents].
Topics: Adult; Cystinuria; Diuresis; Female; Humans; Prognosis; Recurrence; Tiopronin; Ureteral Calculi; Uri | 1985 |