tiopronin has been researched along with Uremia in 1 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Excerpt | Relevance | Reference |
|---|---|---|
| ") of cisplatin (6 mg/kg; 20 micromol/kg) to female Wistar albino rats caused a sustained decrease in body weight and, after 5 days, plasma urea, creatinine and kidney weight were increased." | 3.70 | Tiopronin protects against the nephrotoxicity of cisplatin in the rat. ( Esposito, M; Lindup, WE; Viale, M; Zhang, JG, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhang, JG | 1 |
| Viale, M | 1 |
| Esposito, M | 1 |
| Lindup, WE | 1 |
1 other study available for tiopronin and Uremia
| Article | Year |
|---|---|
Tiopronin protects against the nephrotoxicity of cisplatin in the rat.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Body Weight; Cisplatin; Creatinine; Dose-Respo | 1999 |