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tiopronin and Nephrotic Syndrome

tiopronin has been researched along with Nephrotic Syndrome in 14 studies

Tiopronin: Sulfhydryl acylated derivative of GLYCINE.

Nephrotic Syndrome: A condition characterized by severe PROTEINURIA, greater than 3.5 g/day in an average adult. The substantial loss of protein in the urine results in complications such as HYPOPROTEINEMIA; generalized EDEMA; HYPERTENSION; and HYPERLIPIDEMIAS. Diseases associated with nephrotic syndrome generally cause chronic kidney dysfunction.

Research Excerpts

ExcerptRelevanceReference
" Pediatricians should be aware of this adverse effect of tiopronin, and therefore, testing of the urine with strips or sulfosalicylic acid at least once weekly at home may be very helpful for early detection of proteinuria."7.77Nephrotic syndrome occurring during tiopronin treatment for cystinuria. ( Gucev, Z; Lozanovski, VJ; Ristoska-Bojkovska, N; Sahpazova, E; Tasic, V, 2011)
"A case of nephrotic syndrome with ascites and heart failure in a patient who had received tiopronin for the treatment of cystinuria is presented."7.71[Nephrotic syndrome and anasarca status, secondary to treatment with tiopronin in a case of cystinuria]. ( Alvarez Navascués, R; Herrera Pérez de Villar, J; Rodríguez Suarez, C; Suarez Heiva, M; Vidau Argüelles, P, 2001)
"A 73-year-old patient developed severe nephrotic syndrome with minimal glomerular lesions 6 weeks after tiopronin therapy was initiated."7.70[Tiopronin-induced nephrotic syndrome with minimal glomerular lesions]. ( Duvic, C; Hérody, M; Lecoules, S; Nédélec, G, 1999)
"In the basic treatment of 25 cases of classic or ARA defined rheumatoid arthritis, Tiopronin (alpha-mercaptopropionylglycine) was used for one year."7.67[Basic treatment of rheumatoid arthritis with tiopronin. A study of 25 cases]. ( Buonavia, A; Guidoni, G; Lavagni, A; Maestrini, M; Mordini, M, 1989)
"Tiopronin, a glycine derivative extensively used to treat cystinuria and hepatic cell injury, can give rise to rare complications such as proteinuria and nephrotic syndrome."3.80Tiopronin-induced membranous nephropathy: a case report. ( Jia, J; Lin, S; Shang, W; Wei, L; Xue, Y; Zheng, Z, 2014)
" Pediatricians should be aware of this adverse effect of tiopronin, and therefore, testing of the urine with strips or sulfosalicylic acid at least once weekly at home may be very helpful for early detection of proteinuria."3.77Nephrotic syndrome occurring during tiopronin treatment for cystinuria. ( Gucev, Z; Lozanovski, VJ; Ristoska-Bojkovska, N; Sahpazova, E; Tasic, V, 2011)
"A case of nephrotic syndrome with ascites and heart failure in a patient who had received tiopronin for the treatment of cystinuria is presented."3.71[Nephrotic syndrome and anasarca status, secondary to treatment with tiopronin in a case of cystinuria]. ( Alvarez Navascués, R; Herrera Pérez de Villar, J; Rodríguez Suarez, C; Suarez Heiva, M; Vidau Argüelles, P, 2001)
"A 73-year-old patient developed severe nephrotic syndrome with minimal glomerular lesions 6 weeks after tiopronin therapy was initiated."3.70[Tiopronin-induced nephrotic syndrome with minimal glomerular lesions]. ( Duvic, C; Hérody, M; Lecoules, S; Nédélec, G, 1999)
"In the basic treatment of 25 cases of classic or ARA defined rheumatoid arthritis, Tiopronin (alpha-mercaptopropionylglycine) was used for one year."3.67[Basic treatment of rheumatoid arthritis with tiopronin. A study of 25 cases]. ( Buonavia, A; Guidoni, G; Lavagni, A; Maestrini, M; Mordini, M, 1989)
"Nephrotic syndrome was suggested and renal biopsy was performed."2.38A case of nephrotic syndrome due to alpha-mercaptopropionyl glycine in a patient with familial cystinuria. ( Ishimoto, F; Kodama, K; Murai, S; Nakano, H; Sakai, O; Shibasaki, T, 1990)
"The causes of the recurrences in the other 2 children are discussed."1.26Cystinuria in children. ( Dussini, N; Pagano, F; Passerini, G; Pavanello, L; Rizzoni, G; Tasca, A; Zacchello, G, 1981)
" A relatively high dosage resulted in a reduction of the cytinuria."1.25[Cystine stone therapy with mercapto-propyonyl-glycine (MPG) (Thiola) (author's transl)]. ( Stuhlsatz, HW; Terhorst, B, 1975)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19906 (42.86)18.7374
1990's4 (28.57)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Micallef, S1
Delicata, L1
Agius, JF1
Holwill, S1
Zheng, Z1
Xue, Y1
Jia, J1
Wei, L1
Shang, W1
Lin, S1
Tasic, V1
Lozanovski, VJ1
Ristoska-Bojkovska, N1
Sahpazova, E1
Gucev, Z1
Pavanello, L2
Rizzoni, G2
Dussini, N2
Zacchello, G2
Passerini, G1
Tasca, A1
Pagano, F1
Koeger, AC1
Palazzo, E1
De Person, JF1
Huchet, B1
Kahn, MF1
Bourgeois, P1
Dubois, A1
Blotman, F1
Combe, B1
Lecoules, S1
Duvic, C1
Hérody, M1
Nédélec, G1
Alvarez Navascués, R1
Vidau Argüelles, P1
Rodríguez Suarez, C1
Herrera Pérez de Villar, J1
Suarez Heiva, M1
Chiandetti, L1
Reveillaud, RJ1
Blanc, G1
Daudon, M1
Terhorst, B1
Stuhlsatz, HW1
Shibasaki, T1
Murai, S1
Kodama, K1
Nakano, H1
Ishimoto, F1
Sakai, O1
Mordini, M1
Guidoni, G1
Maestrini, M1
Buonavia, A1
Lavagni, A1
Salvarani, C1
Macchioni, P1
Rossi, F1
Iori, I1
Filippi, G1

Reviews

1 review available for tiopronin and Nephrotic Syndrome

ArticleYear
A case of nephrotic syndrome due to alpha-mercaptopropionyl glycine in a patient with familial cystinuria.
    Nihon Jinzo Gakkai shi, 1990, Volume: 32, Issue:8

    Topics: Adult; Cystinuria; Glomerulonephritis, Membranous; Humans; Male; Nephrotic Syndrome; Tiopronin

1990

Other Studies

13 other studies available for tiopronin and Nephrotic Syndrome

ArticleYear
Tiopronin-induced membranous nephropathy in a patient with refractory familial cystinuria.
    British journal of hospital medicine (London, England : 2005), 2022, 08-02, Volume: 83, Issue:8

    Topics: Cystinuria; Glomerulonephritis, Membranous; Humans; Nephrotic Syndrome; Tiopronin

2022
Tiopronin-induced membranous nephropathy: a case report.
    Renal failure, 2014, Volume: 36, Issue:9

    Topics: Aged; Glomerulonephritis, Membranous; Humans; Kidney; Male; Nephrotic Syndrome; Proteinuria; Tiopron

2014
Nephrotic syndrome occurring during tiopronin treatment for cystinuria.
    European journal of pediatrics, 2011, Volume: 170, Issue:2

    Topics: Amino Acids, Sulfur; Benzenesulfonates; Child, Preschool; Cystinuria; Edema; Humans; Lithotripsy; Ma

2011
Cystinuria in children.
    European urology, 1981, Volume: 7, Issue:3

    Topics: Amino Acids, Sulfur; Child; Child, Preschool; Cystinuria; Female; Humans; Infant; Kidney Calculi; Ma

1981
[Subacute development of nephrotic syndrome caused by tiopronin therapy. A propos of 4 cases].
    Revue du rhumatisme (Ed. francaise : 1993), 1993, Volume: 60, Issue:1

    Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Nephrotic Syndrome; Tiopronin

1993
Nephrotic syndrome and renal failure induced by tiopronin in patients with rheumatoid arthritis.
    The Journal of rheumatology, 1997, Volume: 24, Issue:10

    Topics: Adolescent; Arthritis, Rheumatoid; Biopsy; Female; Humans; Middle Aged; Nephrotic Syndrome; Renal In

1997
[Tiopronin-induced nephrotic syndrome with minimal glomerular lesions].
    Presse medicale (Paris, France : 1983), 1999, Feb-13, Volume: 28, Issue:6

    Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthralgia; Arthritis, Rheumatoid; Diclofenac; Dose-R

1999
[Nephrotic syndrome and anasarca status, secondary to treatment with tiopronin in a case of cystinuria].
    Archivos espanoles de urologia, 2001, Volume: 54, Issue:5

    Topics: Adult; Ascites; Cystinuria; Edema; Female; Humans; Nephrotic Syndrome; Tiopronin

2001
Nephrotic syndrome during treatment with alpha-mercaptopropionylglycine.
    The Journal of urology, 1979, Volume: 122, Issue:3

    Topics: Amino Acids, Sulfur; Child; Child, Preschool; Cystinuria; Humans; Male; Nephrotic Syndrome; Proteinu

1979
[Nephrotic syndrome and skin disorders appearing during alpha-mercapto-propionyl-glycine treatment of 2 cases of cystinic lithiasis].
    Journal d'urologie et de nephrologie, 1978, Volume: 84, Issue:9

    Topics: Adult; Amino Acids, Sulfur; Cystine; Female; Humans; Kidney Calculi; Male; Nephrotic Syndrome; Pruri

1978
[Cystine stone therapy with mercapto-propyonyl-glycine (MPG) (Thiola) (author's transl)].
    Der Urologe. Ausg. A, 1975, Volume: 14, Issue:4

    Topics: Adult; Amino Acids; Amino Acids, Sulfur; Cystinuria; Drug Tolerance; Female; Humans; Long-Term Care;

1975
[Basic treatment of rheumatoid arthritis with tiopronin. A study of 25 cases].
    Minerva medica, 1989, Volume: 80, Issue:9

    Topics: Adult; Aged; Ageusia; Arthritis, Rheumatoid; Drug Evaluation; Female; Humans; Male; Middle Aged; Nep

1989
Nephrotic syndrome induced by tiopronin: association with the HLA-DR3 antigen.
    Arthritis and rheumatism, 1985, Volume: 28, Issue:5

    Topics: Amino Acids, Sulfur; Female; Histocompatibility Antigens Class II; HLA-DR3 Antigen; Humans; Middle A

1985