tiopronin has been researched along with Liver Dysfunction in 15 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Isoniazid is a widely used drug for the treatment of tuberculosis, but hepatotoxicity is a major concern during treatment." | 1.35 | Protective effects of thiopronin against isoniazid-induced hepatotoxicity in rats. ( Chen, J; Dong, G; He, C; Liu, Y; Peng, R; Yue, J, 2009) |
| "Tiopronin suppressed increase in serum transaminase activity, accumulation of liver triglyceride and decrease of liver glucose-6-phosphatase activity induced by CCl4." | 1.26 | [Effect of thiol compounds on experimental liver damage (I). Preventive effect of tiopronin (2-mercaptopropionylglycine) on liver damage induced by carbon tetrachloride (author's transl)]. ( Chiba, T; Horiuchi, M; Nomura, M; Takase, K, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (80.00) | 18.7374 |
| 1990's | 2 (13.33) | 18.2507 |
| 2000's | 1 (6.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yue, J | 1 |
| Dong, G | 1 |
| He, C | 1 |
| Chen, J | 1 |
| Liu, Y | 1 |
| Peng, R | 1 |
| De Pergola, E | 1 |
| Carrozzini, B | 1 |
| Selvaggio, G | 1 |
| De Pergola, G | 1 |
| Sakr, SA | 1 |
| Chiba, T | 3 |
| Horiuchi, M | 3 |
| Akashi, Y | 2 |
| Zimmer, G | 1 |
| Ohlenschläger, G | 1 |
| Berger, J | 1 |
| Takase, K | 1 |
| Nomura, M | 1 |
| Cortinovis, A | 1 |
| Paolini, FA | 1 |
| Crippa, A | 1 |
| Marinai, E | 1 |
| Ulivieri, P | 1 |
| Righi, A | 1 |
| Precchia, G | 1 |
| d'Amico, A | 1 |
| Precchia, E | 1 |
| Precchia, A | 1 |
| Vela, R | 1 |
| Cerrati, A | 1 |
| Markoff, NG | 1 |
| Dioguardi, N | 1 |
| Ideo, G | 1 |
| De Franchis, R | 1 |
| Ronchi, G | 1 |
| Kurumaji, Y | 1 |
| Miyazaki, K | 1 |
| Hsiao, L | 1 |
| Yoshinaga, A | 1 |
| Ono, T | 1 |
1 trial available for tiopronin and Liver Dysfunction
| Article | Year |
|---|---|
[Controlled clinical trial of 2-mercapto-propionyl-glycine in chronic hepatopathies].
Topics: Amino Acids, Sulfur; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Tiopronin; | 1976 |
14 other studies available for tiopronin and Liver Dysfunction
| Article | Year |
|---|---|
Protective effects of thiopronin against isoniazid-induced hepatotoxicity in rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Alanine Transaminase; Aniline Compounds; Animals; Aspartate Aminotransf | 2009 |
[Therapy of hepatic diseases with alpha-mercaptopropionylglycine].
Topics: Amino Acids, Sulfur; Ascites; Hepatitis B; Hepatitis, Alcoholic; Humans; Liver Cirrhosis; Liver Dise | 1982 |
Effect of thiola on acetaminophen induced hepatic necrosis in mice.
Topics: Acetaminophen; Animals; Behavior, Animal; Chemical and Drug Induced Liver Injury; Drug Interactions; | 1993 |
[Effect of thiol compounds on experimental liver damage (III). Effect of tiopronin (2-mercaptopropionylglycine) and glutathione on drug metabolizing activity (author's transl)].
Topics: Amino Acids, Sulfur; Aminopyrine; Aminopyrine N-Demethylase; Aniline Hydroxylase; Animals; Chemical | 1979 |
[Biochemical and clinical studies on the influence of 2-mercaptopropionylglycine on liver cell function (author's transl)].
Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acids, Sulfur; Animals; Biological Transpor | 1978 |
[Effect of thiol compounds on experimental liver damage (I). Preventive effect of tiopronin (2-mercaptopropionylglycine) on liver damage induced by carbon tetrachloride (author's transl)].
Topics: Alanine Transaminase; Amino Acids, Sulfur; Animals; Carbon Tetrachloride Poisoning; Chemical and Dru | 1979 |
[Evaluation of the fraction of hepatocyte depuration before and after treatment with alpha-mercaptopropionylglycine in chronic hepatopathies].
Topics: Amino Acids, Sulfur; Chronic Disease; Humans; Liver; Liver Diseases; Liver Function Tests; Sulfobrom | 1979 |
[Effects of thiol compounds on experimental liver damage (II). Preventive and therapeutic effects of tiopronin (2-mercaptopropionylglycine) and glutathione on ethionine induced liver damage (author's transl)].
Topics: Amino Acids, Sulfur; Animals; Body Weight; Chemical and Drug Induced Liver Injury; Ethionine; Female | 1979 |
[Study of changes in certain immunoglobulin fractions in acute and chronic hepatopathies treated with alpha-mercaptopropionylglycine].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Amino Acids, Sulfur; Chronic Disease; Humans; Immu | 1977 |
[Effects of Thiola in post-hepatitis hepatic insufficiency].
Topics: Adolescent; Adult; Age Factors; Aged; Alkaline Phosphatase; Amino Acids, Sulfur; Bilirubin; Child; C | 1977 |
[Protection induced by some pharmacological molecules with prevalent hepatoprotective activity against toxic effects provoked by hyperbaric oxygenation].
Topics: Animals; Female; Glutathione; Hyperbaric Oxygenation; Ketoglutaric Acids; Liver; Liver Diseases; Mal | 1976 |
[Treatment of acute and chronic liver disease as well as several malabsorption syndromes with 2 mercaptopropionylglycine MPG (thiola) (author's transl)].
Topics: Acute Disease; Amino Acids, Sulfur; Chronic Disease; Humans; Liver Diseases; Malabsorption Syndromes | 1975 |
Tiopronin-induced lichenoid eruption in a patient with liver disease and positive patch test reaction to drugs with sulfhydryl group.
Topics: Drug Eruptions; Female; Humans; Lichen Planus; Liver Diseases; Middle Aged; Skin Tests; Tiopronin | 1990 |
Drug-induced bullous lichen planus in a patient with diabetes mellitus and liver disease.
Topics: Aged; Amino Acids, Sulfur; Diabetes Complications; Female; Humans; Lichen Planus; Liver Diseases; Sk | 1986 |