Page last updated: 2024-11-05

tiopronin and Kidney Stones

tiopronin has been researched along with Kidney Stones in 19 studies

Tiopronin: Sulfhydryl acylated derivative of GLYCINE.

Research Excerpts

ExcerptRelevanceReference
"Cystinuria is the most common monogenic nephrolithiasis disorder."2.72[Cystinuria]. ( Courbebaisse, M; Daudon, M; Defazio, J; Dousseaux, MP; Knebelmann, B; Prot-Bertoye, C; Tostivint, I; Traxer, O, 2021)
"Cystinuria is a complex hereditary disorder characterized by excessive urinary excretion of cystine."1.27Management of the patient with cystinuria. ( Pahira, JJ, 1987)
"The causes of the recurrences in the other 2 children are discussed."1.26Cystinuria in children. ( Dussini, N; Pagano, F; Passerini, G; Pavanello, L; Rizzoni, G; Tasca, A; Zacchello, G, 1981)
"Cystinuria is an inherited disorder of amino acid transport affecting the epithelial cells of the renal tubules and the gastro-intestinal tract."1.26[Clinical aspects of cystinuria and its treatment by thiola (author's transl)]. ( Gründig, E; Latal, D; Müller, M; Zechner, O, 1976)

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's4 (21.05)18.2507
2000's1 (5.26)29.6817
2010's0 (0.00)24.3611
2020's2 (10.53)2.80

Authors

AuthorsStudies
Modersitzki, F1
Goldfarb, DS1
Goldstein, RL1
Sur, RL1
Penniston, KL1
Prot-Bertoye, C1
Daudon, M2
Tostivint, I1
Dousseaux, MP1
Defazio, J1
Traxer, O1
Knebelmann, B1
Courbebaisse, M1
Knoll, T1
Janitzky, V1
Michel, MS1
Alken, P1
Köhrmann, KU1
Pak, CY2
Koide, T2
Kinoshita, K1
Takemoto, M1
Yachiku, S1
Sonoda, T2
Pavanello, L1
Rizzoni, G1
Dussini, N1
Zacchello, G1
Passerini, G1
Tasca, A1
Pagano, F1
Dimopoulos, C1
Stokidis, D1
Kallistratos, G1
Sidéris, C1
Kyriakidis, A1
Kollias, G1
Hayase, Y1
Fukatsu, H1
Segawa, A1
Lindell, A1
Denneberg, T1
Hellgren, E1
Jeppsson, JO1
Tiselius, HG1
Pierides, AM1
Deltas, CC1
Berio, A3
Piazzi, A1
Reveillaud, RJ1
Blanc, G1
Zechner, O1
Latal, D1
Gründig, E1
Müller, M1
Yoshioka, T1
Yamaguchi, S1
Utsunomiya, M1
de Temple, R1
Brien, G1
Hellmann, C1
Otting, U1
Schöpke, W1
Schönberger, B1
Fuller, C1
Sakhaee, K1
Zerwekh, JE1
Adams, BV1
Pahira, JJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage[NCT01095731]Phase 260 participants (Actual)Interventional2010-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for tiopronin and Kidney Stones

ArticleYear
[Cystinuria].
    Nephrologie & therapeutique, 2021, Volume: 17S

    Topics: Cystine; Cystinuria; Humans; Kidney Calculi; Penicillamine; Tiopronin

2021
[Cystinuria - Cystine Stones: Recommendations for Diagnosis, Therapy and Follow-up].
    Aktuelle Urologie, 2003, Volume: 34, Issue:2

    Topics: Adult; Age Factors; Angiotensin-Converting Enzyme Inhibitors; Ascorbic Acid; Captopril; Chelating Ag

2003

Trials

2 trials available for tiopronin and Kidney Stones

ArticleYear
Clinical course and cystine stone formation during tiopronin treatment.
    Urological research, 1995, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Cystinuria; Female; Humans; Kidney Calculi; Male; Middle

1995
Management of cystine nephrolithiasis with alpha-mercaptopropionylglycine.
    The Journal of urology, 1986, Volume: 136, Issue:5

    Topics: Adolescent; Adult; Aged; Amino Acids, Sulfur; Child; Clinical Trials as Topic; Cystine; Cystinuria;

1986

Other Studies

15 other studies available for tiopronin and Kidney Stones

ArticleYear
Assessment of health-related quality of life in patients with cystinuria on tiopronin therapy.
    Urolithiasis, 2020, Volume: 48, Issue:4

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cross-Sectional Studies; Cystinuria; Female; Humans; Kid

2020
Rational therapy of nephrolithiasis, Part II.
    Rational drug therapy, 1984, Volume: 18, Issue:12

    Topics: Allopurinol; Benzothiadiazines; Cellulose; Citrates; Citric Acid; Diuretics; Humans; Kidney Calculi;

1984
Conservative treatment of cystine calculi: effect of oral alpha-mercaptopropionylglycine on cystine stone dissolution and on prevention of stone recurrence.
    The Journal of urology, 1982, Volume: 128, Issue:3

    Topics: Adolescent; Adult; Amino Acids, Sulfur; Cystine; Female; Humans; Kidney Calculi; Male; Recurrence; T

1982
Cystinuria in children.
    European urology, 1981, Volume: 7, Issue:3

    Topics: Amino Acids, Sulfur; Child; Child, Preschool; Cystinuria; Female; Humans; Infant; Kidney Calculi; Ma

1981
[The use of mercapto-propionyl-glycine in the treatment of cystine lithiasis (author's transl)].
    Journal d'urologie, 1981, Volume: 87, Issue:5

    Topics: Adult; Amino Acids, Sulfur; Cystinuria; Female; Humans; Kidney Calculi; Male; Recurrence; Tiopronin;

1981
Dissolution of cystine stones by irrigated tiopronin solution.
    The Journal of urology, 1980, Volume: 124, Issue:6

    Topics: Adolescent; Adult; Amino Acids, Sulfur; Catheterization; Child, Preschool; Cystine; Female; Humans;

1980
Clinical aspects of cystinuria.
    Contributions to nephrology, 1997, Volume: 122

    Topics: Adolescent; Adult; Chelating Agents; Child; Child, Preschool; Cystine; Cystinuria; Diet; Female; Hum

1997
Prophylaxis of cystine calculi by low dose of alpha-mercapto-propionyl-glycine administered every other day.
    Panminerva medica, 1998, Volume: 40, Issue:3

    Topics: Adult; Cystinuria; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Kidney Ca

1998
[Cystine-lysine-ornithine-argininuria. Current genetic and clinico-therapeutic problems].
    Minerva pediatrica, 1979, Oct-31, Volume: 31, Issue:20

    Topics: Adolescent; Amino Acid Metabolism, Inborn Errors; Amino Acids, Sulfur; Arginine; Child; Child, Presc

1979
[Nephrotic syndrome and skin disorders appearing during alpha-mercapto-propionyl-glycine treatment of 2 cases of cystinic lithiasis].
    Journal d'urologie et de nephrologie, 1978, Volume: 84, Issue:9

    Topics: Adult; Amino Acids, Sulfur; Cystine; Female; Humans; Kidney Calculi; Male; Nephrotic Syndrome; Pruri

1978
[Clinical aspects of cystinuria and its treatment by thiola (author's transl)].
    Wiener klinische Wochenschrift, 1976, Feb-06, Volume: 88, Issue:3

    Topics: Amino Acids; Amino Acids, Sulfur; Biological Transport; Cystinuria; Humans; Kidney Calculi; Tioproni

1976
A strategy of cystine stone management.
    The Journal of urology, 1992, Volume: 147, Issue:1

    Topics: Adult; Apatites; Cystine; Female; Humans; Kidney Calculi; Lithotripsy; Middle Aged; Nephrostomy, Per

1992
[Treatment and metaphylaxis of cystine urolithiasis in children].
    Kinderarztliche Praxis, 1989, Volume: 57, Issue:9

    Topics: Acetylcysteine; Administration, Oral; Adolescent; Cystinuria; Female; Humans; Kidney Calculi; Nephro

1989
Management of the patient with cystinuria.
    The Urologic clinics of North America, 1987, Volume: 14, Issue:2

    Topics: Adult; Alkalies; Child; Cystinuria; Dietary Proteins; Female; Fluid Therapy; Humans; Kidney Calculi;

1987
[Prophylaxis of cystinic calculosis with alpha mercapto propionylglycine. Personal cases].
    Minerva pediatrica, 1985, Dec-31, Volume: 37, Issue:23-24

    Topics: Adolescent; Adult; Amino Acids, Sulfur; Cystinuria; Electrophoresis; Humans; Kidney Calculi; Male; M

1985