tiopronin has been researched along with Hypoxia in 9 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
Hypoxia: Sub-optimal OXYGEN levels in the ambient air of living organisms.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In vitro studies were performed to obtain the optimal dosage of the antioxidants N-(2-mercaptopropionyl)-glycine and and catalase to be used in subsequent in vivo experimental studies; cardiac homogenates were incubated in 0 to 5 mmol/L concentrations of the oxidant t-butylhydroperoxide and malondialdehyde production was measured." | 1.29 | Studies of hypoxemic/reoxygenation injury: without aortic clamping. VI. Counteraction of oxidant damage by exogenous antioxidants: N-(2-mercaptopropionyl)-glycine and catalase. ( Buckberg, GD; Ihnken, K; Morita, K; Sherman, MP; Young, HH, 1995) |
| "Of these, six piglets did not undergo hypoxemia (blood cardioplegic control) and 14 others remained hypoxemic (oxygen tension about 25 mm Hg) for up to 2 hours by lowering ventilator fraction of inspired oxygen before reoxygenation on cardiopulmonary bypass." | 1.29 | Studies of hypoxemic/reoxygenation injury: with aortic clamping. X. Exogenous antioxidants to avoid nullification of the cardioprotective effects of blood cardioplegia. ( Buckberg, GD; Ihnken, K; Matheis, G; Morita, K; Sherman, MP; Young, HH, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 4 (44.44) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (22.22) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wu, L | 1 |
| Tan, JL | 1 |
| Wang, ZH | 1 |
| Chen, YX | 1 |
| Gao, L | 1 |
| Liu, JL | 1 |
| Shi, YH | 1 |
| Endoh, M | 1 |
| Yang, HT | 1 |
| Lin, YK | 1 |
| Lai, MS | 1 |
| Chen, YC | 1 |
| Cheng, CC | 1 |
| Huang, JH | 1 |
| Chen, SA | 1 |
| Chen, YJ | 1 |
| Lin, CI | 1 |
| Ihnken, K | 2 |
| Morita, K | 2 |
| Buckberg, GD | 3 |
| Sherman, MP | 3 |
| Young, HH | 3 |
| Matheis, G | 2 |
| Modig, HG | 1 |
| Edgren, M | 1 |
| Révész, L | 1 |
| Haybron, DM | 1 |
| Ignarro, LJ | 1 |
| Tsao, PS | 1 |
| Lefer, AM | 1 |
| Beyersdorf, F | 1 |
| Zimmer, G | 2 |
| Fuchs, J | 2 |
| Kraft, H | 1 |
| Veit, P | 1 |
| Satter, P | 1 |
| Bereiter-Hahn, J | 1 |
9 other studies available for tiopronin and Hypoxia
| Article | Year |
|---|---|
ROS generated during early reperfusion contribute to intermittent hypobaric hypoxia-afforded cardioprotection against postischemia-induced Ca(2+) overload and contractile dysfunction via the JAK2/STAT3 pathway.
Topics: Animals; Calcium; Free Radical Scavengers; Gene Expression Regulation; Hypoxia; Ischemic Preconditio | 2015 |
Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium.
Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atrial Fibrillation; Blotting, Western; Chloramphe | 2012 |
Studies of hypoxemic/reoxygenation injury: without aortic clamping. VI. Counteraction of oxidant damage by exogenous antioxidants: N-(2-mercaptopropionyl)-glycine and catalase.
Topics: Alkadienes; Animals; Cardiopulmonary Bypass; Catalase; Dose-Response Relationship, Drug; Hemodynamic | 1995 |
Studies of hypoxemic/reoxygenation injury: with aortic clamping. X. Exogenous antioxidants to avoid nullification of the cardioprotective effects of blood cardioplegia.
Topics: Alkadienes; Animals; Aorta; Cardiopulmonary Bypass; Catalase; Constriction; Heart Arrest, Induced; H | 1995 |
Effect of radioprotective aminothiols on the induction and repair of single-strand breaks in the DNA of irradiated mammalian cells.
Topics: Amino Acids, Sulfur; Animals; Cell Line; Cricetinae; Cysteamine; DNA; DNA Repair; Hypoxia; Oxygen; Q | 1977 |
Role of L-arginine-nitric oxide pathway in myocardial reoxygenation injury.
Topics: Animals; Animals, Newborn; Arginine; Cardiopulmonary Bypass; Catalase; Hypoxia; Myocardial Reperfusi | 1992 |
Time course and mechanism of endothelial dysfunction in isolated ischemic- and hypoxic-perfused rat hearts.
Topics: Animals; Coronary Disease; Endothelium, Vascular; Heart; Humans; Hypoxia; In Vitro Techniques; Male; | 1990 |
Improvement of myocardial function after global hypoxia by protection of the inner mitochondrial membrane.
Topics: Adenosine Diphosphate; Adenosine Triphosphatases; Adenosine Triphosphate; Amino Acids, Sulfur; Anima | 1987 |
A multiparameter analysis of the perfused rat heart: responses to ischemia, uncouplers and drugs.
Topics: Adenosine Triphosphate; Animals; Coronary Disease; Female; Fluorescent Dyes; Heart; Hypoxia; In Vitr | 1987 |