tiopronin has been researched along with Fanconi Anemia in 1 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
Fanconi Anemia: Congenital disorder affecting all bone marrow elements, resulting in ANEMIA; LEUKOPENIA; and THROMBOPENIA, and associated with cardiac, renal, and limb malformations as well as dermal pigmentary changes. Spontaneous CHROMOSOME BREAKAGE is a feature of this disease along with predisposition to LEUKEMIA. There are at least 7 complementation groups in Fanconi anemia: FANCA, FANCB, FANCC, FANCD1, FANCD2, FANCE, FANCF, FANCG, and FANCL. (from Online Mendelian Inheritance in Man, http://www.ncbi.nlm.nih.gov/entrez/dispomim.cgi?id=227650, August 20, 2004)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Peripheral blood lymphocytes from eight Fanconi anemia (FA) patients, 14 FA heterozygotes, and nine normal subjects have been tested for their susceptibility to chromosomal breakage induction by diepoxybutane (DEB) and by two peroxides." | 3.67 | Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes. ( Alimena, G; Dallapiccola, B; Gandini, E; Isacchi, G; Mokini, V; Porfirio, B, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dallapiccola, B | 1 |
| Porfirio, B | 1 |
| Mokini, V | 1 |
| Alimena, G | 1 |
| Isacchi, G | 1 |
| Gandini, E | 1 |
1 other study available for tiopronin and Fanconi Anemia
| Article | Year |
|---|---|
Effect of oxidants and antioxidants on chromosomal breakage in Fanconi anemia lymphocytes.
Topics: Anemia, Aplastic; Antioxidants; Ascorbic Acid; Cells, Cultured; Chromosome Aberrations; Cross-Linkin | 1985 |