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tiopronin and Experimental Radiation Injuries

tiopronin has been researched along with Experimental Radiation Injuries in 26 studies

Tiopronin: Sulfhydryl acylated derivative of GLYCINE.

Research Excerpts

ExcerptRelevanceReference
"After 24 h, chromosomal aberrations were studied in the bone marrow of the femur by routine metaphase preparation after colchicine treatment."1.30A comparative study of radioprotection by Ocimum flavonoids and synthetic aminothiol protectors in the mouse. ( Bisht, KS; Devi, PU; Vinitha, M, 1998)
" The effectiveness of two doses of WR-2721 (300 mg/kg and 150 mg/kg body weight) alone or in combination with an optimal dose (20 mg/kg body weight) of MPG, on the mouse bone marrow was studied by the exogenous spleen colony assay (CFU-s) after a single whole body exposure to 4."1.28Drug combination against single drug treatment in radiation protection of the bone marrow CFU. ( Bisht, KS; Jagetia, GC; Kamath, G; Uma Devi, P, 1990)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199022 (84.62)18.7374
1990's4 (15.38)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ghose, A5
Ganguly, SK1
Kaur, J2
Patni, N1
Metha, G1
Dev, FU1
Kumar, S2
Uma Devi, P7
Kumar, A4
Pant, RD2
Devi, PU4
Srinivasan, MN1
Bhagat, RM3
Prasanna, PG1
Bisht, KS3
Vinitha, M1
Laconi, A1
Buscemi, M1
Cardinale, A1
De Simone, GF1
Pasqualino, A1
Tessitore, V1
Saini, MR1
Verma, A1
Saharan, BR1
Sugahara, T1
Horikawa, M1
Hikita, M1
Nagata, H1
Kobayashi, S1
Kasuya, M1
Ishii, Y1
Takehana, M1
Sakai, K1
Suzuki, N1
Itoi, M1
Jagetia, GC2
Kamath, G1
Thomas, B1
Mathur, VB2
Ganguly, SU1
Mathur, M1
Khan, AS1
Bhartiya, HC1
Bhartiya, KM1

Reviews

1 review available for tiopronin and Experimental Radiation Injuries

ArticleYear
Studies on radioprotectors in mammals and their possible use in radiotherapy--a summary.
    Radiobiologia, radiotherapia, 1985, Volume: 26, Issue:3

    Topics: Amifostine; Amino Acids, Sulfur; Animals; Drug Combinations; Humans; Mice; Neoplasms; Organothiophos

1985

Other Studies

25 other studies available for tiopronin and Experimental Radiation Injuries

ArticleYear
Protection with combinations of hydroxytryptophan and some thiol compounds against whole-body gamma irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1983, Volume: 44, Issue:2

    Topics: Animals; beta-Aminoethyl Isothiourea; Cobalt Radioisotopes; Cystamine; Cysteamine; Cysteine; Drug Th

1983
Radioprotective effect of MPG on mouse liver irradiated in utero with gamma radiation.
    Radiobiologia, radiotherapia, 1983, Volume: 24, Issue:6

    Topics: Amino Acids, Sulfur; Animals; Cobalt Radioisotopes; Female; Liver; Mice; Mice, Inbred Strains; Pregn

1983
Radioresponse of peripheral blood and its modification by MPG (2-mercaptopropionylglycine) in mice III leucocyte.
    Radiobiologia, radiotherapia, 1983, Volume: 24, Issue:1

    Topics: Amino Acids, Sulfur; Animals; Leukocyte Count; Leukocytes; Mice; Mice, Inbred Strains; Radiation Inj

1983
Chemical protection of mice against radiation induced sickness and mortality by 2-mercaptopropionylglycine.
    Radiobiologia, radiotherapia, 1983, Volume: 24, Issue:2

    Topics: Amino Acids, Sulfur; Animals; Body Weight; Drug Evaluation, Preclinical; Female; Gamma Rays; Mice; M

1983
Effect of MPG and AET on erythrocytes in peripheral blood after gamma irradiation.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1981, Volume: 40, Issue:2

    Topics: Amino Acids, Sulfur; Animals; beta-Aminoethyl Isothiourea; Erythrocyte Count; Erythrocytes; Female;

1981
Chemoprotection of ovarian follicles of mice against gamma irradiation by MPG (2-mercaptopropionylglycine).
    Journal of radiation research, 1982, Volume: 23, Issue:3

    Topics: Amino Acids, Sulfur; Animals; Cobalt Radioisotopes; Female; Gamma Rays; Mice; Ovarian Follicle; Radi

1982
Ineffectiveness of 2-mercaptopropionylglycine in increasing survival of mice after gamma irradiation either alone or in combination with 2-aminoethyl isothiuronium bromide hydrobromide.
    Journal of radiation research, 1980, Volume: 21, Issue:3-4

    Topics: Amino Acids, Sulfur; Animals; beta-Aminoethyl Isothiourea; Gamma Rays; Mice; Prognosis; Radiation In

1980
Effect of 2-mercaptopropionylglycine and 2-aminoethyl isothiuronium bromide hydrobromide on leucocytes in peripheral blood after gamma ray exposure in mice.
    Journal of radiation research, 1981, Volume: 22, Issue:4

    Topics: Amino Acids, Sulfur; Animals; beta-Aminoethyl Isothiourea; Cobalt Radioisotopes; Female; Leukopenia;

1981
Radioprotective effect of 2-mercaptopropionylglycine (2-MPG) on the haematology of Swiss albino mice after radiocalcium (Ca-45) internal administration.
    Radiobiologia, radiotherapia, 1981, Volume: 22, Issue:5

    Topics: Amino Acids, Sulfur; Animals; Calcium Radioisotopes; Erythrocyte Count; Erythrocytes; Hematocrit; Le

1981
Modification of WR-2721 radiation protection from gastrointestinal injury and death in mice by 2-mercaptopropionylglycine.
    Radiation research, 1993, Volume: 133, Issue:1

    Topics: Amifostine; Animals; Drug Therapy, Combination; Gastrointestinal Diseases; Mice; Mice, Inbred Strain

1993
A comparative study of radioprotection by Ocimum flavonoids and synthetic aminothiol protectors in the mouse.
    The British journal of radiology, 1998, Volume: 71, Issue:847

    Topics: Amifostine; Animals; Bone Marrow; Chromosome Aberrations; Flavonoids; Mice; Plant Extracts; Radiatio

1998
[Protective effect of complexogenic drugs (BAL, alpha-mercaptopropionyl-glycine) on some enzyme activities of the kidney of rats treated with chlormerodrin-Hg197. Histochemical studies].
    Bollettino della Societa italiana di biologia sperimentale, 1975, Jul-15, Volume: 51, Issue:13

    Topics: Acetylglucosaminidase; Adenosine Triphosphatases; Amino Acids, Sulfur; Animals; Chlormerodrin; Dimer

1975
Radioprotective effect of 2-mercaptopropionylglycine on the small intestine of Swiss albino mice.
    Indian journal of experimental biology, 1977, Volume: 16, Issue:1

    Topics: Amino Acids, Sulfur; Animals; Ileum; Male; Mice; Radiation Injuries, Experimental; Radiation-Protect

1977
Studies on a sulfhydryl radioprotector of low toxicity.
    Experientia. Supplementum, 1977, Volume: 27

    Topics: Amino Acids, Sulfur; Animals; Cell Survival; Cysteamine; Dose-Response Relationship, Drug; Female; H

1977
Protection of mouse intestine against gamma irradiation by 2-mercaptopriopionylglycine (MPG).
    Journal of radiation research, 1977, Volume: 18, Issue:2

    Topics: Amino Acids, Sulfur; Animals; Intestine, Small; Mice; Radiation Injuries, Experimental; Radiation-Pr

1977
Effects of 2-mercaptopropionylglycine on the development of X-ray-induced cataract in rats.
    Current eye research, 1992, Volume: 11, Issue:11

    Topics: Animals; Cataract; Female; Injections, Intraperitoneal; Lens, Crystalline; Radiation Injuries, Exper

1992
Drug combination against single drug treatment in radiation protection of the bone marrow CFU.
    Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 1990, Volume: 166, Issue:8

    Topics: Amifostine; Animals; Bone Marrow; Colony-Forming Units Assay; Drug Combinations; Mice; Organothiopho

1990
Bone marrow cell protection and modification of drug toxicity by combination of protectors.
    Pharmacology & therapeutics, 1988, Volume: 39, Issue:1-3

    Topics: Amifostine; Animals; Bone Marrow; Chromosome Aberrations; Drug Therapy, Combination; Mice; Radiation

1988
MPG protection and crypt cell kinetics in mouse ileum.
    Radiobiologia, radiotherapia, 1988, Volume: 29, Issue:4

    Topics: Animals; Cell Count; Ileum; Male; Mice; Radiation Injuries, Experimental; Radiation-Protective Agent

1988
Recovery from radiation injury by 2-mercaptopropionylglycine in lymphocytes of mouse bone marrow.
    Radiobiologia, radiotherapia, 1987, Volume: 28, Issue:6

    Topics: Amino Acids, Sulfur; Animals; Bone Marrow; Calcium Radioisotopes; Lymphocytes; Male; Mice; Mice, Inb

1987
Radioprotection to mice by combination of hydroxytryptophan with AET or MPG: bone marrow histology study.
    Radiobiologia, radiotherapia, 1987, Volume: 28, Issue:4

    Topics: 5-Hydroxytryptophan; Amino Acids, Sulfur; Animals; beta-Aminoethyl Isothiourea; Bone Marrow; Male; M

1987
MPG modification of adrenal response in Swiss albino mice exposed to gamma radiation.
    Radiobiologia, radiotherapia, 1986, Volume: 27, Issue:6

    Topics: Adrenal Cortex; Amino Acids, Sulfur; Animals; Cobalt Radioisotopes; Gamma Rays; Male; Mice; Mice, In

1986
Modification of haemoglobin level and haematocrit value in the peripheral blood of mice after 45Ca internal irradiation by MPG (2-mercaptopropionylglycine).
    Radiobiologia, radiotherapia, 1986, Volume: 27, Issue:4

    Topics: Amino Acids, Sulfur; Animals; Calcium Radioisotopes; Hematocrit; Hemoglobins; Male; Mice; Radiation

1986
Effect of gamma irradiation and radioprotector MPG on liver glycogen in mice.
    Radiobiologia, radiotherapia, 1986, Volume: 27, Issue:4

    Topics: Amino Acids, Sulfur; Animals; Liver; Liver Glycogen; Male; Mice; Radiation Injuries, Experimental; R

1986
Influence of 2-mercaptopropionylglycine (MPG) on radiation-induced changes in the acid phosphatase activity of mouse intestine and its role in tissue protection.
    Radiobiologia, radiotherapia, 1986, Volume: 27, Issue:4

    Topics: Acid Phosphatase; Amino Acids, Sulfur; Animals; Ileum; Male; Mice; Radiation Injuries, Experimental;

1986