tiopronin has been researched along with Chronic Disease in 11 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
Chronic Disease: Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).
| Excerpt | Relevance | Reference |
|---|---|---|
| "The efficacy of tiopronin (2-mercaptopropionyl glycine) 600 mg daily in the treatment of chronic active or chronic persistent hepatitis has been assessed in a double-blind controlled clinical trial of 12 weeks involving 165 Japanese patients with histologically proven disease." | 9.05 | Therapeutic effects of tiopronin on chronic hepatitis: a double-blind clinical study. ( Fujisawa, K; Hirasawa, T; Hirayama, C; Ichida, F; Inoue, J; Inoue, K; Kaito, I; Kameda, H; Kosaka, Y; Nagashima, H; Ohta, Y; Okada, J; Satoh, G; Shibasaki, K; Suzuki, H; Takino, T; Tsuji, T; Yamamoto, S, 1982) |
| "Follow-up studies were conducted in the patients with chronic active hepatitis treated 10 years ago with tiopronin (TP) or corticosteroids (CS)." | 7.66 | Follow-up study in chronic active hepatitis after therapies with immunosuppressive drugs and tiopronin. ( Nagashima, H; Tsuji, T, 1981) |
| "The efficacy of tiopronin (2-mercaptopropionyl glycine) 600 mg daily in the treatment of chronic active or chronic persistent hepatitis has been assessed in a double-blind controlled clinical trial of 12 weeks involving 165 Japanese patients with histologically proven disease." | 5.05 | Therapeutic effects of tiopronin on chronic hepatitis: a double-blind clinical study. ( Fujisawa, K; Hirasawa, T; Hirayama, C; Ichida, F; Inoue, J; Inoue, K; Kaito, I; Kameda, H; Kosaka, Y; Nagashima, H; Ohta, Y; Okada, J; Satoh, G; Shibasaki, K; Suzuki, H; Takino, T; Tsuji, T; Yamamoto, S, 1982) |
| "Follow-up studies were conducted in the patients with chronic active hepatitis treated 10 years ago with tiopronin (TP) or corticosteroids (CS)." | 3.66 | Follow-up study in chronic active hepatitis after therapies with immunosuppressive drugs and tiopronin. ( Nagashima, H; Tsuji, T, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ichida, F | 1 |
| Shibasaki, K | 1 |
| Takino, T | 1 |
| Suzuki, H | 1 |
| Fujisawa, K | 1 |
| Inoue, K | 1 |
| Hirayama, C | 1 |
| Kaito, I | 1 |
| Hirasawa, T | 1 |
| Kameda, H | 1 |
| Inoue, J | 1 |
| Satoh, G | 1 |
| Kosaka, Y | 1 |
| Yamamoto, S | 1 |
| Nagashima, H | 2 |
| Tsuji, T | 2 |
| Ohta, Y | 1 |
| Okada, J | 1 |
| Valente, U | 1 |
| Campisi, C | 1 |
| Barabino, C | 1 |
| De Rosa, E | 1 |
| Traverso, C | 1 |
| Pozzati, A | 1 |
| Fontana, I | 1 |
| Mazzetti, M | 1 |
| Guizzardi, G | 1 |
| Meliconi, R | 1 |
| Baraldini, M | 1 |
| Stancari, MV | 1 |
| Mazzoli, M | 1 |
| Stefanini, GF | 1 |
| Cortinovis, A | 1 |
| Paolini, FA | 1 |
| Crippa, A | 1 |
| Marinai, E | 1 |
| Ulivieri, P | 1 |
| Righi, A | 1 |
| Surrenti, C | 1 |
| Arcangeli, A | 1 |
| Casini, A | 1 |
| Markoff, NG | 1 |
| Dioguardi, N | 1 |
| Ideo, G | 1 |
| De Franchis, R | 1 |
| Ronchi, G | 1 |
| Straneo, G | 1 |
| Avanzini, F | 1 |
| Scaglione, F | 2 |
| Coppi, G | 2 |
| Fraschini, F | 2 |
| Piazza, G | 1 |
| Marchi, E | 1 |
| Montoli, CC | 1 |
| Scarpazza, G | 1 |
3 trials available for tiopronin and Chronic Disease
| Article | Year |
|---|---|
Therapeutic effects of tiopronin on chronic hepatitis: a double-blind clinical study.
Topics: Acyltransferases; Amino Acids, Sulfur; Chronic Disease; Clinical Trials as Topic; Double-Blind Metho | 1982 |
[The action of thiopronine in the treatment of chronic recurrent pancreatitis. Double-blind study of 105 patients].
Topics: Adult; Amino Acids, Sulfur; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; | 1983 |
[Controlled clinical trial of 2-mercapto-propionyl-glycine in chronic hepatopathies].
Topics: Amino Acids, Sulfur; Chronic Disease; Hepatitis; Humans; Liver Cirrhosis; Liver Diseases; Tiopronin; | 1976 |
8 other studies available for tiopronin and Chronic Disease
| Article | Year |
|---|---|
[Effect of 2 mercaptopropionylglycine on the cytotoxic activity of lymphocytes from patients with chronic active hepatitis against rabbit hepatocytes isolated and cultured in vitro].
Topics: Amino Acids, Sulfur; Animals; Chronic Disease; Cytotoxicity Tests, Immunologic; Hepatitis B; Hepatit | 1981 |
Follow-up study in chronic active hepatitis after therapies with immunosuppressive drugs and tiopronin.
Topics: Adult; Amino Acids, Sulfur; Chronic Disease; Drug Therapy, Combination; Follow-Up Studies; Hepatitis | 1981 |
[Evaluation of the fraction of hepatocyte depuration before and after treatment with alpha-mercaptopropionylglycine in chronic hepatopathies].
Topics: Amino Acids, Sulfur; Chronic Disease; Humans; Liver; Liver Diseases; Liver Function Tests; Sulfobrom | 1979 |
[Study of changes in certain immunoglobulin fractions in acute and chronic hepatopathies treated with alpha-mercaptopropionylglycine].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Amino Acids, Sulfur; Chronic Disease; Humans; Immu | 1977 |
[The antisteatosic activity of 2-MPG (Thiola). Study with the (BSF) dynamic test and with liver biopsy before and after the treatment].
Topics: Adult; Aged; Amino Acids, Sulfur; Chronic Disease; Drug Evaluation; Fatty Liver; Female; Humans; Liv | 1978 |
[Treatment of acute and chronic liver disease as well as several malabsorption syndromes with 2 mercaptopropionylglycine MPG (thiola) (author's transl)].
Topics: Acute Disease; Amino Acids, Sulfur; Chronic Disease; Humans; Liver Diseases; Malabsorption Syndromes | 1975 |
[Protective activity of tiopronin in relation to the acute exacerbation of chronic bronchitis].
Topics: Aged; Amino Acids, Sulfur; Bronchitis; Chronic Disease; Female; Humans; Length of Stay; Male; Middle | 1987 |
Some aspects of "deep lung" cellular immunity in chronic bronchitis before and after therapy with tiopronin.
Topics: Aged; Amino Acids, Sulfur; Antibodies, Monoclonal; Bronchitis; Chronic Disease; Female; Humans; Macr | 1987 |