tiopronin has been researched along with Cardiovascular Stroke in 28 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The hypothesis that blockade of angiotensin II type 1 (AT1) receptors after myocardial infarction prevents coronary endothelial vasomotor dysfunction by suppressing oxygen free radical production was examined." | 7.71 | Blockade of angiotensin II type 1 receptors suppressed free radical production and preserved coronary endothelial function in the rabbit heart after myocardial infarction. ( Hasegawa, T; Kuno, A; Miki, T; Miura, T; Nishino, Y; Shimamoto, K; Tsuchida, A, 2002) |
| "The hypothesis that blockade of angiotensin II type 1 (AT1) receptors after myocardial infarction prevents coronary endothelial vasomotor dysfunction by suppressing oxygen free radical production was examined." | 3.71 | Blockade of angiotensin II type 1 receptors suppressed free radical production and preserved coronary endothelial function in the rabbit heart after myocardial infarction. ( Hasegawa, T; Kuno, A; Miki, T; Miura, T; Nishino, Y; Shimamoto, K; Tsuchida, A, 2002) |
| "Myocardial infarction was induced by 20-minute coronary occlusion/reperfusion in spontaneously hypertensive stroke-prone rats (SHR-SPs) and their controls (Wistar-Kyoto rats [WKYs])." | 1.37 | Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection. ( Itoh, T; Kouzu, H; Kuno, A; Miki, T; Miura, T; Sato, T; Shimamoto, K; Takada, A; Tanno, M; Yano, T, 2011) |
| "Bucillamine is a potent sulfhydryl donor not previously tested as a treatment of reperfusion injury." | 1.31 | Bucillamine prevents myocardial reperfusion injury. ( Horwitz, LD; Sherman, NA, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (10.71) | 18.7374 |
| 1990's | 9 (32.14) | 18.2507 |
| 2000's | 13 (46.43) | 29.6817 |
| 2010's | 3 (10.71) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nadtochiy, SM | 1 |
| Burwell, LS | 1 |
| Ingraham, CA | 1 |
| Spencer, CM | 1 |
| Friedman, AE | 1 |
| Pinkert, CA | 1 |
| Brookes, PS | 1 |
| Yano, T | 1 |
| Miki, T | 3 |
| Tanno, M | 1 |
| Kuno, A | 2 |
| Itoh, T | 1 |
| Takada, A | 1 |
| Sato, T | 1 |
| Kouzu, H | 1 |
| Shimamoto, K | 2 |
| Miura, T | 2 |
| Andreadou, I | 1 |
| Iliodromitis, EK | 1 |
| Souridis, V | 1 |
| Prokovas, E | 1 |
| Kostidis, S | 1 |
| Zoga, A | 1 |
| Dagres, N | 1 |
| Tsantili-Kakoulidou, A | 1 |
| Kremastinos, DT | 1 |
| Mikros, E | 1 |
| Anastasiou-Nana, M | 1 |
| Belevych, AE | 1 |
| Terentyev, D | 1 |
| Terentyeva, R | 1 |
| Ho, HT | 1 |
| Gyorke, I | 1 |
| Bonilla, IM | 1 |
| Carnes, CA | 1 |
| Billman, GE | 1 |
| Györke, S | 1 |
| Yue, Y | 1 |
| Qin, Q | 1 |
| Cohen, MV | 4 |
| Downey, JM | 5 |
| Critz, SD | 1 |
| McLeod, CJ | 1 |
| Jeyabalan, AP | 1 |
| Minners, JO | 1 |
| Clevenger, R | 1 |
| Hoyt, RF | 1 |
| Sack, MN | 1 |
| Chen, YS | 1 |
| Chien, CT | 1 |
| Ma, MC | 1 |
| Tseng, YZ | 1 |
| Lin, FY | 1 |
| Wang, SS | 1 |
| Chen, CF | 1 |
| Bell, RM | 1 |
| Cave, AC | 1 |
| Johar, S | 1 |
| Hearse, DJ | 1 |
| Shah, AM | 1 |
| Shattock, MJ | 1 |
| Lecour, S | 1 |
| Owira, P | 1 |
| Opie, LH | 1 |
| Sovershaev, MA | 1 |
| Egorina, EM | 1 |
| Andreasen, TV | 1 |
| Jonassen, AK | 1 |
| Ytrehus, K | 1 |
| Gross, GJ | 1 |
| Hsu, A | 1 |
| Falck, JR | 1 |
| Nithipatikom, K | 1 |
| Dost, T | 1 |
| Matsuhisa, S | 1 |
| Otani, H | 1 |
| Okazaki, T | 1 |
| Yamashita, K | 1 |
| Akita, Y | 1 |
| Sato, D | 1 |
| Moriguchi, A | 1 |
| Imamura, H | 1 |
| Iwasaka, T | 1 |
| Widman, SC | 1 |
| Liang, CS | 1 |
| Schenk, EA | 1 |
| Hood, WB | 1 |
| Tanaka, M | 1 |
| Fujiwara, H | 1 |
| Yamasaki, K | 1 |
| Sasayama, S | 1 |
| Horwitz, LD | 3 |
| Fennessey, PV | 1 |
| Shikes, RH | 1 |
| Kong, Y | 2 |
| Richard, V | 1 |
| Tron, C | 1 |
| Thuillez, C | 1 |
| Baines, CP | 1 |
| Goto, M | 1 |
| Yamashita, N | 2 |
| Hoshida, S | 2 |
| Taniguchi, N | 2 |
| Kuzuya, T | 2 |
| Hori, M | 2 |
| Robertson, AD | 1 |
| Yang, XM | 1 |
| Liu, GS | 1 |
| Heusch, G | 1 |
| Sherman, NA | 1 |
| Tsuchida, A | 1 |
| Hasegawa, T | 1 |
| Nishino, Y | 1 |
| Beyersdorf, F | 1 |
| Acar, C | 1 |
| Buckberg, GD | 1 |
| Partington, MT | 1 |
| Okamoto, F | 1 |
| Allen, BS | 1 |
| Young, HH | 1 |
| Bugyi, HI | 1 |
| Kiricuta, IC | 1 |
| Schmitt, WG | 1 |
| Beyer, HK | 1 |
| Mitsos, SE | 1 |
| Askew, TE | 1 |
| Fantone, JC | 1 |
| Kunkel, SL | 1 |
| Abrams, GD | 1 |
| Schork, A | 1 |
| Lucchesi, BR | 1 |
1 review available for tiopronin and Cardiovascular Stroke
| Article | Year |
|---|---|
[Possibilities of phosphorus 31 spectroscopy in assessing the therapeutic effects on cellular energy metabolism of the myocardium].
Topics: Acebutolol; Cardioplegic Solutions; Chlorpromazine; Energy Metabolism; Humans; Magnetic Resonance Sp | 1989 |
27 other studies available for tiopronin and Cardiovascular Stroke
| Article | Year |
|---|---|
In vivo cardioprotection by S-nitroso-2-mercaptopropionyl glycine.
Topics: Animals; Cardiotonic Agents; Electron Transport Complex I; Ischemic Preconditioning, Myocardial; Mal | 2009 |
Hypertensive hypertrophied myocardium is vulnerable to infarction and refractory to erythropoietin-induced protection.
Topics: Animals; Calcium; Cardiomegaly; Erythropoietin; Hypertension; Male; Mitochondria, Heart; Mitochondri | 2011 |
Investigating the effect of antioxidant treatment on the protective effect of preconditioning in anesthetized rabbits.
Topics: Animals; Antioxidants; Glutathione; Infusions, Intravenous; Ischemic Preconditioning, Myocardial; Li | 2011 |
Shortened Ca2+ signaling refractoriness underlies cellular arrhythmogenesis in a postinfarction model of sudden cardiac death.
Topics: Adrenergic beta-Agonists; Animals; Benzylamines; Caffeine; Calcium Channel Agonists; Calcium Signali | 2012 |
The relative order of mK(ATP) channels, free radicals and p38 MAPK in preconditioning's protective pathway in rat heart.
Topics: Animals; Anisomycin; Decanoic Acids; Diazoxide; Enzyme Activators; Enzyme Inhibitors; Free Radical S | 2002 |
Delayed ischemic preconditioning activates nuclear-encoded electron-transfer-chain gene expression in parallel with enhanced postanoxic mitochondrial respiratory recovery.
Topics: Adenosine Triphosphate; Animals; Cell Hypoxia; Drug Administration Schedule; Electron Transport Chai | 2004 |
Protection "outside the box" (skeletal remote preconditioning) in rat model is triggered by free radical pathway.
Topics: Animals; Blood Pressure; Free Radicals; Glutathione Peroxidase; Heart Rate; Heat-Shock Proteins; HSP | 2005 |
Pivotal role of NOX-2-containing NADPH oxidase in early ischemic preconditioning.
Topics: Acridines; Alkaloids; Animals; Benzophenanthridines; Coloring Agents; Heart; Ischemia; Ischemic Prec | 2005 |
Ceramide-induced preconditioning involves reactive oxygen species.
Topics: Animals; Antioxidants; Catalase; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Male; My | 2006 |
Preconditioning by 17beta-estradiol in isolated rat heart depends on PI3-K/PKB pathway, PKC, and ROS.
Topics: Alkaloids; Androstadienes; Animals; Benzophenanthridines; Dose-Response Relationship, Drug; Enzyme I | 2006 |
Mechanisms by which epoxyeicosatrienoic acids (EETs) elicit cardioprotection in rat hearts.
Topics: 8,11,14-Eicosatrienoic Acid; Adenosine Triphosphate; Animals; Male; Myocardial Infarction; Potassium | 2007 |
Redox signaling triggers protection during the reperfusion rather than the ischemic phase of preconditioning.
Topics: Animals; Ischemic Preconditioning, Myocardial; Myocardial Infarction; Myocardial Ischemia; Myocardia | 2008 |
Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart.
Topics: Aldehydes; Amidines; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzylamines; D | 2008 |
Contraction band necrosis: its modification by the free radical scavenger N-2-mercaptopropionyl glycine.
Topics: Animals; Blood Pressure; Coronary Circulation; Coronary Disease; Disease Models, Animal; Dogs; Femal | 1994 |
Superoxide dismutase and N-2-mercaptopropionyl glycine attenuate infarct size limitation effect of ischaemic preconditioning in the rabbit.
Topics: Animals; Free Radicals; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Rabbits; Super | 1994 |
Marked reduction in myocardial infarct size due to prolonged infusion of an antioxidant during reperfusion.
Topics: Animals; Coronary Circulation; Dogs; Free Radical Scavengers; Hydrogen Peroxide; Infusions, Intraven | 1994 |
Ischaemic preconditioning is not mediated by oxygen derived free radicals in rats.
Topics: Animals; Free Radical Scavengers; Male; Myocardial Infarction; Myocardial Ischemia; Myocardial Reper | 1993 |
Oxygen radicals released during ischemic preconditioning contribute to cardioprotection in the rabbit myocardium.
Topics: Analysis of Variance; Animals; Enzyme Activation; Female; Free Radical Scavengers; Free Radicals; He | 1997 |
A "second window of protection" occurs 24 h after ischemic preconditioning in the rat heart.
Topics: Animals; Incidence; Ischemic Preconditioning, Myocardial; Male; Myocardial Infarction; Myocardial Is | 1998 |
Whole-body hyperthermia provides biphasic cardioprotection against ischemia/reperfusion injury in the rat.
Topics: Animals; Antioxidants; Enzyme Induction; Free Radicals; Heat-Shock Proteins; HSP72 Heat-Shock Protei | 1998 |
Timing of treatment for myocardial reperfusion injury.
Topics: Animals; Antioxidants; Dogs; Female; Hemodynamics; Male; Myocardial Infarction; Myocardial Reperfusi | 1999 |
Failure of N-2-mercaptopropionyl glycine to reduce myocardial infarction after 3 days of reperfusion in rabbits.
Topics: Animals; Dogs; Humans; Myocardial Infarction; Myocardial Reperfusion; Rabbits; Species Specificity; | 1999 |
Acetylcholine, bradykinin, opioids, and phenylephrine, but not adenosine, trigger preconditioning by generating free radicals and opening mitochondrial K(ATP) channels.
Topics: Acetylcholine; Adenosine; Animals; Bradykinin; Decanoic Acids; Free Radical Scavengers; Free Radical | 2001 |
Bucillamine prevents myocardial reperfusion injury.
Topics: Animals; Cells, Cultured; Collateral Circulation; Coronary Circulation; Cysteine; Dogs; Dose-Respons | 2001 |
Blockade of angiotensin II type 1 receptors suppressed free radical production and preserved coronary endothelial function in the rabbit heart after myocardial infarction.
Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Endothelium, Vascular; Enz | 2002 |
Studies on prolonged acute regional ischemia. V. Metabolic support of remote myocardium during left ventricular power failure.
Topics: Animals; Aspartic Acid; Coronary Circulation; Dogs; Glucose; Glutamates; Hemodynamics; Infusions, In | 1989 |
Protective effects of N-2-mercaptopropionyl glycine against myocardial reperfusion injury after neutrophil depletion in the dog: evidence for the role of intracellular-derived free radicals.
Topics: Amino Acids, Sulfur; Animals; Cell Movement; Dogs; Free Radicals; Hemodynamics; Male; Myocardial Inf | 1986 |