tiopronin has been researched along with Acantholysis in 5 studies
Tiopronin: Sulfhydryl acylated derivative of GLYCINE.
Acantholysis: Separation of the prickle cells of the stratum spinosum of the epidermis, resulting in atrophy of the prickle cell layer. It is seen in diseases such as pemphigus vulgaris (see PEMPHIGUS) and DARIER DISEASE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Focal acantholysis was seen in specimens cultured with L-cysteine or GSH at a 15-mM concentration." | 5.27 | In vitro acantholysis by captopril and thiopronine. ( de Angelis, E; Lombardi, ML; Pisani, M; Ruocco, V, 1988) |
| "To explain the molecular mechanism of enalapril-induced acantholysis a potential link between transglutaminase (TGase) activity and the effects of this drug was investigated." | 3.69 | Are acantholysis and transglutaminase inhibition related phenomena? ( Cozzolino, A; Esposito, C; Lombardi, ML; LoSchiavo, A; Porta, R; Ruocco, V, 1996) |
| ", penicillamine, captopril, thiopronine) can induce pemphigus in vivo and provoke acantholysis in vitro." | 3.68 | Enalapril: a powerful in vitro non-thiol acantholytic agent. ( de Angelis, E; Grassi, M; Lombardi, ML; Ruocco, V, 1992) |
| "Focal acantholysis was seen in specimens cultured with L-cysteine or GSH at a 15-mM concentration." | 1.27 | In vitro acantholysis by captopril and thiopronine. ( de Angelis, E; Lombardi, ML; Pisani, M; Ruocco, V, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lombardi, ML | 5 |
| de Angelis, E | 4 |
| Rossano, F | 1 |
| Ruocco, V | 5 |
| Esposito, C | 1 |
| Cozzolino, A | 1 |
| LoSchiavo, A | 1 |
| Porta, R | 1 |
| Grassi, M | 1 |
| Pisani, M | 2 |
5 other studies available for tiopronin and Acantholysis
| Article | Year |
|---|---|
Imbalance between plasminogen activator and its inhibitors in thiol-induced acantholysis.
Topics: Acantholysis; Captopril; Culture Media; Culture Techniques; Epidermis; Humans; Penicillamine; Plasmi | 1993 |
Are acantholysis and transglutaminase inhibition related phenomena?
Topics: Acantholysis; Angiotensin-Converting Enzyme Inhibitors; Binding, Competitive; Biochemical Phenomena; | 1996 |
Enalapril: a powerful in vitro non-thiol acantholytic agent.
Topics: Acantholysis; Captopril; Culture Techniques; Enalapril; Female; Humans; Immunoglobulin G; Penicillam | 1992 |
Biochemical acantholysis provoked by thiol drugs.
Topics: Acantholysis; Captopril; Humans; Pemphigus; Penicillamine; Skin Diseases; Sulfhydryl Compounds; Tiop | 1990 |
In vitro acantholysis by captopril and thiopronine.
Topics: Acantholysis; Adult; Aged; Amino Acids, Sulfur; Captopril; Cysteine; Female; Glutathione; Humans; In | 1988 |