tinidazole has been researched along with Stomach Ulcer in 16 studies
Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.
Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Levofloxacin-tinidazole-based triple therapy was highly effective and safe as a first-line regimen in Indian patients with gastroduodenal ulcer disease associated with H." | 9.17 | Safety and efficacy of 1-week levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori-related peptic ulcer disease in Kashmir, India. ( Gulzar, GM; Javid, G; Khan, BA; Khan, MA; Saif, R; Shah, A; Shoukat, A; Sodhi, JS; Teli, F; Yattoo, GN; Zargar, SA, 2013) |
| "Levofloxacin-tinidazole-based triple therapy was highly effective and safe as a first-line regimen in Indian patients with gastroduodenal ulcer disease associated with H." | 5.17 | Safety and efficacy of 1-week levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori-related peptic ulcer disease in Kashmir, India. ( Gulzar, GM; Javid, G; Khan, BA; Khan, MA; Saif, R; Shah, A; Shoukat, A; Sodhi, JS; Teli, F; Yattoo, GN; Zargar, SA, 2013) |
| "During a period of 1 year 152 patients with gastric ulcers were randomly assigned to one of two treatment regimens: omeprazole 20 mg daily in the morning for 8 weeks (74 patients), or bismuth subsalicylate 600 mg three times daily for 8 weeks combined with 500 mg amoxicillin twice daily and 1000 mg tinidazole twice daily for the first 10 days (triple therapy) (78 patients)." | 5.08 | Cure of gastric ulcer disease after cure of Helicobacter pylori infection--German Gastric Ulcer Study. ( Bästlein, E; Bayerdörffer, E; Bolle, KH; Hatz, R; Heldwein, W; Höchter, W; Klann, H; Lehn, N; Mannes, GA; Meining, A; Miehlke, S; Ruckdeschel, G; Simon, T; Sommer, A; Stolte, M; Weingart, J, 1996) |
| "Lansoprazole has a cytotoxic action against this organism, the MIC being 2." | 1.29 | Effect of lansoprazole in mono-, dual-, or triple therapy on Helicobacter pylori eradication. ( Kawano, S; Murakami, M; Saita, H; Tsuji, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 9 (56.25) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Choi, HS | 1 |
| Chun, HJ | 1 |
| Park, SH | 1 |
| Keum, B | 1 |
| Seo, YS | 1 |
| Kim, YS | 1 |
| Jeen, YT | 1 |
| Um, SH | 1 |
| Lee, HS | 1 |
| Kim, CD | 1 |
| Ryu, HS | 1 |
| Shah, A | 1 |
| Javid, G | 1 |
| Zargar, SA | 1 |
| Teli, F | 1 |
| Khan, BA | 1 |
| Yattoo, GN | 1 |
| Gulzar, GM | 1 |
| Sodhi, JS | 1 |
| Khan, MA | 1 |
| Shoukat, A | 1 |
| Saif, R | 1 |
| Brzozowski, T | 1 |
| Konturek, PC | 1 |
| Kwiecien, S | 1 |
| Konturek, SJ | 1 |
| Pajdo, R | 1 |
| Drozdowicz, D | 1 |
| Ptak, A | 1 |
| Pawlik, M | 1 |
| Stachura, J | 1 |
| Pawlik, WW | 1 |
| Hahn, EG | 1 |
| Herszényi, L | 1 |
| Ziemniak, W | 1 |
| Choné, L | 1 |
| Fléjou, JF | 1 |
| Grignon, Y | 1 |
| Bigard, MA | 1 |
| Bayerdörffer, E | 2 |
| Miehlke, S | 2 |
| Lehn, N | 2 |
| Mannes, GA | 2 |
| Höchter, W | 1 |
| Weingart, J | 1 |
| Klann, H | 1 |
| Sommer, A | 1 |
| Heldwein, W | 1 |
| Hatz, R | 1 |
| Simon, T | 1 |
| Bolle, KH | 1 |
| Bästlein, E | 2 |
| Meining, A | 2 |
| Ruckdeschel, G | 1 |
| Stolte, M | 2 |
| Kawano, S | 1 |
| Murakami, M | 1 |
| Saita, H | 1 |
| Tsuji, S | 1 |
| Moshkowitz, M | 1 |
| Konikoff, FM | 1 |
| Peled, Y | 1 |
| Brill, S | 1 |
| Hallak, A | 1 |
| Tiomny, E | 1 |
| Santo, M | 1 |
| Bujanover, Y | 1 |
| Gilat, T | 1 |
| Boixeda de Miquel, D | 1 |
| Oderda, G | 1 |
| Ponzetto, A | 1 |
| Boero, M | 1 |
| Bellis, D | 1 |
| Forni, M | 1 |
| Vaira, D | 1 |
| Ansaldi, N | 1 |
| Bardhan, KD | 1 |
| Morton, D | 1 |
| Slater, DN | 1 |
| Perry, MJ | 1 |
| Cherian, P | 1 |
| Jones, RB | 1 |
| Brookes, A | 1 |
| Thompson, M | 1 |
| Morris, P | 1 |
| McCaldin, B | 1 |
| Cammarota, G | 1 |
| Papa, A | 1 |
| Cianci, R | 1 |
| Cannizzaro, O | 1 |
| Armuzzi, A | 1 |
| Gasbarrini, A | 1 |
| Addolorato, G | 1 |
| Gasbarrini, GB | 1 |
| Zullo, A | 1 |
| Rinaldi, V | 1 |
| Winn, S | 1 |
| Meddi, P | 1 |
| Lionetti, R | 1 |
| Hassan, C | 1 |
| Ripani, C | 1 |
| Tomaselli, G | 1 |
| Attili, AF | 1 |
| Garcia, N | 1 |
| Calvet, X | 1 |
| Gené, E | 1 |
| Campo, R | 1 |
| Brullet, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Phase 4, Prospective, Randomized and Comparative Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice[NCT01273441] | Phase 4 | 338 participants (Actual) | Interventional | 2010-12-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tinidazole and Stomach Ulcer
| Article | Year |
|---|---|
[Eradication of Helicobacter pylori].
Topics: Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Drug Therapy, Combination; Duodenal Ulcer; Enzym | 2003 |
9 trials available for tinidazole and Stomach Ulcer
| Article | Year |
|---|---|
Comparison of sequential and 7-, 10-, 14-d triple therapy for Helicobacter pylori infection.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Alkylating Agents; Amoxicillin; Anti-Bacterial Agents; Anti | 2012 |
Safety and efficacy of 1-week levofloxacin-based triple therapy in first-line treatment for Helicobacter pylori-related peptic ulcer disease in Kashmir, India.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Drug Administration Schedule; Dru | 2013 |
Efficacy of Helicobacter pylori eradication taking into account its resistance to antibiotics.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Aged, 80 and over; Amoxicillin; An | 2006 |
Cure of gastric ulcer disease after cure of Helicobacter pylori infection--German Gastric Ulcer Study.
Topics: Adult; Aged; Amoxicillin; Anti-Ulcer Agents; Biopsy; Bismuth; Drug Administration Schedule; Drug The | 1996 |
One week triple therapy with omeprazole, clarithromycin and tinidazole for Helicobacter pylori: differing efficacy in previously treated and untreated patients.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Child; Clarithromycin; Drug Admin | 1996 |
Family treatment of symptomatic children with Helicobacter pylori infection.
Topics: Adolescent; Adult; Amoxicillin; Carrier State; Child; Child, Preschool; Chronic Disease; Disease Tra | 1997 |
Three-day antibiotic therapy with azithromycin and tinidazole plus lansoprazole or pantoprazole to cure Helicobacter pylori infection: a pilot study.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adolescent; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer | 1999 |
A new highly effective short-term therapy schedule for Helicobacter pylori eradication.
Topics: Administration, Oral; Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Antitricho | 2000 |
Limited usefulness of a seven-day twice-a-day quadruple therapy.
Topics: Adult; Aged; Amoxicillin; Confidence Intervals; Dose-Response Relationship, Drug; Drug Administratio | 2000 |
6 other studies available for tinidazole and Stomach Ulcer
| Article | Year |
|---|---|
Triple eradication therapy counteracts functional impairment associated with Helicobacter pylori infection in Mongolian gerbils.
Topics: Amoxicillin; Animals; Anti-Ulcer Agents; Colony Count, Microbial; Drug Therapy, Combination; Gastric | 2003 |
[Helicobacter heilmannii: new spiral shaped bacterium that may be responsible for ulcerated gastritis].
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Acute Disease; Amoxicillin; Anti-Ulcer Agents; Drug Therapy | 1995 |
Effect of lansoprazole in mono-, dual-, or triple therapy on Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Amoxicillin; Anti-Ulcer Agents; Drug Therapy, Combination; | 1996 |
Helicobacter pylori reinfection is rare in peptic ulcer patients cured by antimicrobial therapy.
Topics: Amoxicillin; Anti-Ulcer Agents; Bismuth; Drug Therapy, Combination; Duodenal Ulcer; Female; Follow-U | 1996 |
[Efficacy of the triple therapy in the eradication of H. pylori in peptic ulcer].
Topics: Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Drug Therapy, Combination; Du | 1997 |
Pantoprazole-based 10-day triple therapy is effective in Helicobacter pylori eradication.
Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Aged; Anti-Bacterial Agents; Anti-Ulcer Agents; Anti | 1998 |