Page last updated: 2024-11-05

tinidazole and Pregnancy

tinidazole has been researched along with Pregnancy in 24 studies

Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Resistance during pregnancy has not been reported."5.37A case of high-level metronidazole-resistant trichomoniasis in pregnancy successfully treated. ( Sobel, JD; Subramanian, C, 2011)
" Metronidazole has become the drug of choice for most cases of giardiasis because of its efficacy, favorable tolerance, and availability."4.78Giardiasis. Issues in diagnosis and management. ( Hill, DR, 1993)
" Teratogenicity tests in animals have given negative results in the case of metronidazole, ornidazole and tinidazole, and in the case of metronidazole no evidence of any adverse effect on the outcome of pregnancy was seen in women treated for trichomoniasis at various times during gestation, including the first trimester."3.67Safety of nitroimidazoles. ( Roe, FJ, 1985)
"Mycophenolic acid was detected in all cats."2.61 ( Abrams, G; Adolfsson, E; Agarwal, PK; Akkan, AG; Al Alhareth, NS; Alves, VGL; Armentano, R; Bahroos, E; Baig, M; Baldridge, KK; Barman, S; Bartolucci, C; Basit, A; Bertoli, SV; Bian, L; Bigatti, G; Bobenko, AI; Boix, PP; Bokulic, T; Bolink, HJ; Borowiec, J; Bulski, W; Burciaga, J; Butt, NS; Cai, AL; Campos, AM; Cao, G; Cao, Y; Čapo, I; Caruso, ML; Chao, CT; Cheatum, CM; Chelminski, K; Chen, AJW; Chen, C; Chen, CH; Chen, D; Chen, G; Chen, H; Chen, LH; Chen, R; Chen, RX; Chen, X; Cherdtrakulkiat, R; Chirvony, VS; Cho, JG; Chu, K; Ciurlino, D; Coletta, S; Contaldo, G; Crispi, F; Cui, JF; D'Esposito, M; de Biase, S; Demir, B; Deng, W; Deng, Z; Di Pinto, F; Domenech-Ximenos, B; Dong, G; Drácz, L; Du, XJ; Duan, LJ; Duan, Y; Ekendahl, D; Fan, W; Fang, L; Feng, C; Followill, DS; Foreman, SC; Fortunato, G; Frew, R; Fu, M; Gaál, V; Ganzevoort, W; Gao, DM; Gao, X; Gao, ZW; Garcia-Alvarez, A; Garza, MS; Gauthier, L; Gazzaz, ZJ; Ge, RS; Geng, Y; Genovesi, S; Geoffroy, V; Georg, D; Gigli, GL; Gong, J; Gong, Q; Groeneveld, J; Guerra, V; Guo, Q; Guo, X; Güttinger, R; Guyo, U; Haldar, J; Han, DS; Han, S; Hao, W; Hayman, A; He, D; Heidari, A; Heller, S; Ho, CT; Ho, SL; Hong, SN; Hou, YJ; Hu, D; Hu, X; Hu, ZY; Huang, JW; Huang, KC; Huang, Q; Huang, T; Hwang, JK; Izewska, J; Jablonski, CL; Jameel, T; Jeong, HK; Ji, J; Jia, Z; Jiang, W; Jiang, Y; Kalumpha, M; Kang, JH; Kazantsev, P; Kazemier, BM; Kebede, B; Khan, SA; Kiss, J; Kohen, A; Kolbenheyer, E; Konai, MM; Koniarova, I; Kornblith, E; Krawetz, RJ; Kreouzis, T; Kry, SF; Laepple, T; Lalošević, D; Lan, Y; Lawung, R; Lechner, W; Lee, KH; Lee, YH; Leonard, C; Li, C; Li, CF; Li, CM; Li, F; Li, J; Li, L; Li, S; Li, X; Li, Y; Li, YB; Li, Z; Liang, C; Lin, J; Lin, XH; Ling, M; Link, TM; Liu, HH; Liu, J; Liu, M; Liu, W; Liu, YP; Lou, H; Lu, G; Lu, M; Lun, SM; Ma, Z; Mackensen, A; Majumdar, S; Martineau, C; Martínez-Pastor, JP; McQuaid, JR; Mehrabian, H; Meng, Y; Miao, T; Miljković, D; Mo, J; Mohamed, HSH; Mohtadi, M; Mol, BWJ; Moosavi, L; Mosdósi, B; Nabu, S; Nava, E; Ni, L; Novakovic-Agopian, T; Nyamunda, BC; Nyul, Z; Önal, B; Özen, D; Özyazgan, S; Pajkrt, E; Palazon, F; Park, HW; Patai, Á; Patai, ÁV; Patzke, GR; Payette, G; Pedoia, V; Peelen, MJCS; Pellitteri, G; Peng, J; Perea, RJ; Pérez-Del-Rey, D; Popović, DJ; Popović, JK; Popović, KJ; Posecion, L; Povall, J; Prachayasittikul, S; Prachayasittikul, V; Prat-González, S; Qi, B; Qu, B; Rakshit, S; Ravelli, ACJ; Ren, ZG; Rivera, SM; Salo, P; Samaddar, S; Samper, JLA; Samy El Gendy, NM; Schmitt, N; Sekerbayev, KS; Sepúlveda-Martínez, Á; Sessolo, M; Severi, S; Sha, Y; Shen, FF; Shen, X; Shen, Y; Singh, P; Sinthupoom, N; Siri, S; Sitges, M; Slovak, JE; Solymosi, N; Song, H; Song, J; Song, M; Spingler, B; Stewart, I; Su, BL; Su, JF; Suming, L; Sun, JX; Tantimavanich, S; Tashkandi, JM; Taurbayev, TI; Tedgren, AC; Tenhunen, M; Thwaites, DI; Tibrewala, R; Tomsejm, M; Triana, CA; Vakira, FM; Valdez, M; Valente, M; Valentini, AM; Van de Winckel, A; van der Lee, R; Varga, F; Varga, M; Villarino, NF; Villemur, R; Vinatha, SP; Vincenti, A; Voskamp, BJ; Wang, B; Wang, C; Wang, H; Wang, HT; Wang, J; Wang, M; Wang, N; Wang, NC; Wang, Q; Wang, S; Wang, X; Wang, Y; Wang, Z; Wen, N; Wesolowska, P; Willis, M; Wu, C; Wu, D; Wu, L; Wu, X; Wu, Z; Xia, JM; Xia, X; Xia, Y; Xiao, J; Xiao, Y; Xie, CL; Xie, LM; Xie, S; Xing, Z; Xu, C; Xu, J; Yan, D; Yan, K; Yang, S; Yang, X; Yang, XW; Ye, M; Yin, Z; Yoon, N; Yoon, Y; Yu, H; Yu, K; Yu, ZY; Zhang, B; Zhang, GY; Zhang, H; Zhang, J; Zhang, M; Zhang, Q; Zhang, S; Zhang, W; Zhang, X; Zhang, Y; Zhang, YW; Zhang, Z; Zhao, D; Zhao, F; Zhao, P; Zhao, W; Zhao, Z; Zheng, C; Zhi, D; Zhou, C; Zhou, FY; Zhu, D; Zhu, J; Zhu, Q; Zinyama, NP; Zou, M; Zou, Z, 2019)
"Resistance during pregnancy has not been reported."1.37A case of high-level metronidazole-resistant trichomoniasis in pregnancy successfully treated. ( Sobel, JD; Subramanian, C, 2011)
"Metronidazole treatment during pregnancy should be resorted to only when absolutely essential."1.28Trichomoniasis: trends in diagnosis and management. ( Kent, HL; Lossick, JG, 1991)

Research

Studies (24)

TimeframeStudies, this research(%)All Research%
pre-199012 (50.00)18.7374
1990's5 (20.83)18.2507
2000's3 (12.50)29.6817
2010's3 (12.50)24.3611
2020's1 (4.17)2.80

Authors

AuthorsStudies
Bobenko, AI1
Heller, S1
Schmitt, N1
Cherdtrakulkiat, R1
Lawung, R1
Nabu, S1
Tantimavanich, S1
Sinthupoom, N1
Prachayasittikul, S1
Prachayasittikul, V1
Zhang, B1
Wu, C1
Zhang, Z2
Yan, K1
Li, C2
Li, Y4
Li, L3
Zheng, C1
Xiao, Y1
He, D1
Zhao, F1
Su, JF1
Lun, SM1
Hou, YJ1
Duan, LJ1
Wang, NC1
Shen, FF1
Zhang, YW1
Gao, ZW1
Li, J5
Du, XJ1
Zhou, FY1
Yin, Z1
Zhu, J2
Yan, D1
Lou, H1
Yu, H1
Feng, C1
Wang, Z1
Wang, Y4
Hu, X1
Li, Z2
Shen, Y1
Hu, D1
Chen, H1
Wu, X1
Duan, Y1
Zhi, D1
Zou, M2
Zhao, Z1
Zhang, X2
Yang, X2
Zhang, J2
Wang, H1
Popović, KJ1
Popović, DJ1
Miljković, D1
Lalošević, D1
Čapo, I1
Popović, JK1
Liu, M1
Song, H2
Xing, Z1
Lu, G1
Chen, D1
Valentini, AM1
Di Pinto, F1
Coletta, S1
Guerra, V1
Armentano, R1
Caruso, ML1
Gong, J1
Wang, N1
Bian, L1
Wang, M1
Ye, M1
Wen, N1
Fu, M1
Fan, W1
Meng, Y1
Dong, G1
Lin, XH1
Liu, HH1
Gao, DM1
Cui, JF1
Ren, ZG1
Chen, RX1
Önal, B1
Özen, D1
Demir, B1
Akkan, AG1
Özyazgan, S1
Payette, G1
Geoffroy, V1
Martineau, C1
Villemur, R1
Jameel, T1
Baig, M1
Gazzaz, ZJ1
Tashkandi, JM1
Al Alhareth, NS1
Khan, SA1
Butt, NS1
Wang, J2
Geng, Y1
Zhang, Y3
Wang, X2
Liu, J2
Basit, A1
Miao, T1
Liu, W1
Jiang, W1
Yu, ZY1
Wu, L2
Qu, B1
Sun, JX1
Cai, AL1
Xie, LM1
Groeneveld, J1
Ho, SL1
Mackensen, A1
Mohtadi, M1
Laepple, T1
Genovesi, S1
Nava, E1
Bartolucci, C1
Severi, S1
Vincenti, A1
Contaldo, G1
Bigatti, G1
Ciurlino, D1
Bertoli, SV1
Slovak, JE1
Hwang, JK1
Rivera, SM1
Villarino, NF1
Li, S1
Cao, G1
Ling, M1
Ji, J1
Zhao, D1
Sha, Y1
Gao, X1
Liang, C2
Guo, Q1
Zhou, C1
Ma, Z1
Xu, J1
Wang, C1
Zhao, W1
Xia, X1
Jiang, Y1
Peng, J1
Jia, Z1
Li, F1
Chen, X2
Mo, J1
Zhang, S2
Li, X1
Huang, T1
Zhu, Q1
Wang, S1
Ge, RS1
Fortunato, G1
Lin, J2
Agarwal, PK1
Kohen, A1
Singh, P1
Cheatum, CM1
Zhu, D1
Hayman, A1
Kebede, B1
Stewart, I1
Chen, G1
Frew, R1
Guo, X1
Gong, Q1
Borowiec, J1
Han, S1
Zhang, M1
Willis, M1
Kreouzis, T1
Yu, K1
Chirvony, VS1
Sekerbayev, KS1
Pérez-Del-Rey, D1
Martínez-Pastor, JP1
Palazon, F1
Boix, PP1
Taurbayev, TI1
Sessolo, M1
Bolink, HJ1
Lu, M1
Lan, Y1
Xiao, J1
Song, M1
Chen, C1
Huang, Q1
Cao, Y1
Ho, CT1
Qi, B1
Wang, Q1
Zhang, W1
Fang, L1
Xie, CL1
Chen, R1
Yang, S1
Xia, JM1
Zhang, GY1
Chen, CH1
Yang, XW1
Domenech-Ximenos, B1
Garza, MS1
Prat-González, S1
Sepúlveda-Martínez, Á1
Crispi, F1
Perea, RJ1
Garcia-Alvarez, A1
Sitges, M1
Kalumpha, M1
Guyo, U1
Zinyama, NP1
Vakira, FM1
Nyamunda, BC1
Varga, M1
Drácz, L1
Kolbenheyer, E1
Varga, F1
Patai, ÁV1
Solymosi, N1
Patai, Á1
Kiss, J1
Gaál, V1
Nyul, Z1
Mosdósi, B1
Valdez, M1
Moosavi, L1
Heidari, A1
Novakovic-Agopian, T1
Kornblith, E1
Abrams, G1
McQuaid, JR1
Posecion, L1
Burciaga, J1
D'Esposito, M1
Chen, AJW1
Samy El Gendy, NM1
Wesolowska, P1
Georg, D1
Lechner, W1
Kazantsev, P1
Bokulic, T1
Tedgren, AC1
Adolfsson, E1
Campos, AM1
Alves, VGL1
Suming, L1
Hao, W1
Ekendahl, D1
Koniarova, I1
Bulski, W1
Chelminski, K1
Samper, JLA1
Vinatha, SP1
Rakshit, S1
Siri, S1
Tomsejm, M1
Tenhunen, M1
Povall, J1
Kry, SF1
Followill, DS1
Thwaites, DI1
Izewska, J1
Kang, JH1
Yoon, Y1
Song, J1
Van de Winckel, A1
Gauthier, L1
Chao, CT1
Lee, YH1
Li, CM1
Han, DS1
Huang, JW1
Huang, KC1
Ni, L1
Güttinger, R1
Triana, CA1
Spingler, B1
Baldridge, KK1
Patzke, GR1
Shen, X1
Wang, B1
Xie, S1
Deng, W1
Wu, D1
Zhang, Q1
Voskamp, BJ1
Peelen, MJCS1
Ravelli, ACJ1
van der Lee, R1
Mol, BWJ1
Pajkrt, E1
Ganzevoort, W1
Kazemier, BM1
Tibrewala, R1
Bahroos, E1
Mehrabian, H1
Foreman, SC1
Link, TM1
Pedoia, V1
Majumdar, S1
Jablonski, CL1
Leonard, C1
Salo, P1
Krawetz, RJ1
Yoon, N1
Hong, SN1
Cho, JG1
Jeong, HK1
Lee, KH1
Park, HW1
Barman, S1
Konai, MM1
Samaddar, S1
Haldar, J1
Mohamed, HSH1
Li, CF1
Hu, ZY1
Deng, Z1
Chen, LH1
Su, BL1
Chu, K1
Liu, YP1
Li, YB1
Zhang, H1
Xu, C1
Zou, Z1
Wu, Z1
Xia, Y1
Zhao, P1
Wang, HT1
de Biase, S1
Pellitteri, G1
Gigli, GL1
Valente, M1
Gadoth, A1
Shannon, CL1
Hoff, NA1
Mvumbi, G1
Musene, K1
Okitolonda-Wemakoy, E1
Hoffman, RM1
Rimoin, AW1
Klausner, JD1
Forbes, GL1
Drayton, R1
Forbes, GD1
Subramanian, C1
Sobel, JD1
Czeizel, AE1
Kazy, Z1
Vargha, P2
Zoltán, K1
Czeizel, E1
Karhunen, M2
Richter, R1
Krohn, K1
Weström, L1
Svensson, L1
Wölner-Hanssen, P1
Mårdh, PA1
Mittendorf, R1
Aronson, MP1
Berry, RE1
Williams, MA1
Kupelnick, B1
Klickstein, A1
Herbst, AL1
Chalmers, TC1
Hill, DR1
Hirvonen, J1
Pyörälä, S1
Heinäsuo, A1
Jousimies-Somer, H1
Mank, TG1
Zaat, JO1
Sucharit, P1
Uthaischant, A1
Chintana, T1
Suphadtanapongs, W1
Eamsobhana, P1
Prasomsitti, P1
Akinla, O1
Ogunbi, O1
Sternadel, Z1
Karwan-Plońska, A1
Peksa, A1
Lossick, JG1
Kent, HL1
Boiadzhieva, N2
Georgieva, I1
Roe, FJ1
Hoyme, UB1
Eschenbach, DA1
Koskela, O1
Teisala, K1
Suikkari, AM1
Mattila, J1
Evaldson, GR1
Lindgren, S1
Nord, CE1
Rane, AT1

Reviews

4 reviews available for tinidazole and Pregnancy

ArticleYear
    Proceedings. Mathematical, physical, and engineering sciences, 2019, Volume: 475, Issue:2227

    Topics: Acetylcholine; Acinetobacter baumannii; Actinobacteria; Action Potentials; Adalimumab; Adaptation, P

2019
Avoiding serious infections associated with abdominal hysterectomy: a meta-analysis of antibiotic prophylaxis.
    American journal of obstetrics and gynecology, 1993, Volume: 169, Issue:5

    Topics: Abdomen; Anti-Bacterial Agents; Cefazolin; Female; Humans; Hysterectomy; Metronidazole; Pregnancy; P

1993
Giardiasis. Issues in diagnosis and management.
    Infectious disease clinics of North America, 1993, Volume: 7, Issue:3

    Topics: Adult; Animals; Child; Child, Preschool; Female; Furazolidone; Giardia lamblia; Giardiasis; Host-Par

1993
Diagnostic advantages and therapeutic options for giardiasis.
    Expert opinion on investigational drugs, 2001, Volume: 10, Issue:8

    Topics: Animals; Antiprotozoal Agents; Female; Giardiasis; HIV Infections; Humans; Metronidazole; Pregnancy;

2001

Trials

4 trials available for tinidazole and Pregnancy

ArticleYear
Investigation of the prophylactic effect of tinidazole on the postoperative infection rate of patients undergoing vacuum aspiration.
    Scandinavian journal of infectious diseases. Supplementum, 1981, Volume: 26

    Topics: Abortion, Induced; Adolescent; Adult; Female; Gestational Age; Humans; Nitroimidazoles; Pregnancy; P

1981
A clinical double-blind study on the effect of prophylactically administered single dose tinidazole on the occurrence of endometritis after first trimester legal abortion.
    Scandinavian journal of infectious diseases. Supplementum, 1981, Volume: 26

    Topics: Abortion, Induced; Adult; Age Factors; Double-Blind Method; Endometritis; Female; Humans; Nitroimida

1981
Treatment of trichomonal vaginitis with single dose tinidazole (Fasigyn).
    West African journal of pharmacology and drug research, 1975, Volume: 2, Issue:1

    Topics: Adult; Clinical Trials as Topic; Female; Humans; Nitroimidazoles; Pregnancy; Tinidazole; Trichomonas

1975
Prophylaxis and treatment of anaerobic infections following caesarean section with tinidazole.
    Chemotherapy, 1985, Volume: 31, Issue:3

    Topics: Adult; Amniotic Fluid; Anaerobiosis; Bacterial Infections; Cesarean Section; Double-Blind Method; En

1985

Other Studies

16 other studies available for tinidazole and Pregnancy

ArticleYear
Prenatal chlamydial, gonococcal, and trichomonal screening in the Democratic Republic of Congo for case detection and management.
    International journal of STD & AIDS, 2020, Volume: 31, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Azithromycin; Chlamydia Infections; Chlamydia trachomatis; Cross-Secti

2020
A case of metronidazole-resistant Trichomonas vaginalis in pregnancy.
    International journal of STD & AIDS, 2016, Volume: 27, Issue:10

    Topics: Antitrichomonal Agents; Drug Resistance; Female; Humans; Metronidazole; Pregnancy; Pregnancy Complic

2016
A case of high-level metronidazole-resistant trichomoniasis in pregnancy successfully treated.
    Journal of lower genital tract disease, 2011, Volume: 15, Issue:3

    Topics: Adult; Anti-Infective Agents; Antitrichomonal Agents; Drug Resistance, Microbial; Female; Humans; Me

2011
Oral tinidazole treatment during pregnancy and teratogenesis.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2003, Volume: 83, Issue:3

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Adult; Antitrichomonal Agents; Case-Control Studi

2003
[Study of the teratogenic effects of oral tinidazole therapy in pregnancy].
    Orvosi hetilap, 2006, May-14, Volume: 147, Issue:19

    Topics: Abnormalities, Drug-Induced; Administration, Oral; Antitrichomonal Agents; Case-Control Studies; Fem

2006
Placental transfer of metronidazole and tinidazole in early human pregnancy after a single infusion.
    British journal of clinical pharmacology, 1984, Volume: 18, Issue:2

    Topics: Adult; Female; Humans; Infusions, Parenteral; Maternal-Fetal Exchange; Metronidazole; Nitroimidazole

1984
Conventional therapy of trichomoniasis.
    Gynakologische Rundschau, 1983, Volume: 23 Suppl 2

    Topics: Antitrichomonal Agents; Female; Gastrointestinal Diseases; Humans; Metronidazole; Ornidazole; Pregna

1983
Penicillin G and penicillin G-tinidazole treatment of experimentally induced summer mastitis--effect on elimination rates of bacteria and outcome of the disease.
    Veterinary microbiology, 1994, Volume: 42, Issue:4

    Topics: Animals; Cattle; Colony Count, Microbial; Drug Therapy, Combination; Female; Mastitis, Bovine; Penic

1994
In vivo and in vitro studies of tinidazole in Trichomonas vaginalis infection.
    The Southeast Asian journal of tropical medicine and public health, 1979, Volume: 10, Issue:4

    Topics: Adolescent; Adult; Female; Humans; Microbial Sensitivity Tests; Nitroimidazoles; Pregnancy; Tinidazo

1979
[Efficacity of a single oral dose of tinidazole (2,000 MG) in the treatment of trichomonas vaginitis].
    Ginekologia polska, 1975, Volume: 46, Issue:7

    Topics: Administration, Oral; Adult; Drug Tolerance; Female; Humans; Nitroimidazoles; Pregnancy; Tinidazole;

1975
Trichomoniasis: trends in diagnosis and management.
    American journal of obstetrics and gynecology, 1991, Volume: 165, Issue:4 Pt 2

    Topics: Drug Resistance; Female; Fluorescent Antibody Technique; Humans; Immunoenzyme Techniques; Latex Fixa

1991
[Experimental research on the effect of bioshik (tinidazole) on reproduction indices].
    Eksperimentalna meditsina i morfologiia, 1990, Volume: 29, Issue:1

    Topics: Administration, Oral; Animals; Dose-Response Relationship, Drug; Female; Male; Nitroimidazoles; Preg

1990
[Effect of bioshik (tinidazole) on fetal growth in pregnant rats].
    Akusherstvo i ginekologiia, 1987, Volume: 26, Issue:3

    Topics: Abnormalities, Drug-Induced; Animals; Female; Fetal Death; Fetal Diseases; Nitroimidazoles; Pregnanc

1987
Safety of nitroimidazoles.
    Scandinavian journal of infectious diseases. Supplementum, 1985, Volume: 46

    Topics: Abnormalities, Drug-Induced; Animals; Chromosome Aberrations; Cricetinae; Dose-Response Relationship

1985
[Bacterial vaginitis. Microbiology, diagnosis, therapy and complications].
    Deutsche medizinische Wochenschrift (1946), 1985, Mar-01, Volume: 110, Issue:9

    Topics: Anti-Bacterial Agents; Chlamydia Infections; Female; Gardnerella vaginalis; Gonorrhea; Haemophilus I

1985
Tinidazole milk excretion and pharmacokinetics in lactating women.
    British journal of clinical pharmacology, 1985, Volume: 19, Issue:4

    Topics: Cesarean Section; Female; Half-Life; Humans; Infusions, Parenteral; Kinetics; Lactation; Milk, Human

1985