tinidazole has been researched along with Pouch Ileitis in 4 studies
Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Sixteen consecutive ulcerative colitis patients with chronic refractory pouchitis (disease>4 weeks and failure to respond to>4 weeks of single-antibiotic therapy) were treated with a four-week course of ciprofloxacin 1 g/day and tinidazole 15 mg/kg/day." | 9.12 | Combined ciprofloxacin and tinidazole therapy in the treatment of chronic refractory pouchitis. ( Bennett, AE; Brzezinski, A; Fazio, VW; Lashner, BA; Lopez, R; Oikonomou, I; Remzi, FH; Shen, B; Sherman, KK, 2007) |
| "Sixteen consecutive ulcerative colitis patients with chronic refractory pouchitis (disease>4 weeks and failure to respond to>4 weeks of single-antibiotic therapy) were treated with a four-week course of ciprofloxacin 1 g/day and tinidazole 15 mg/kg/day." | 5.12 | Combined ciprofloxacin and tinidazole therapy in the treatment of chronic refractory pouchitis. ( Bennett, AE; Brzezinski, A; Fazio, VW; Lashner, BA; Lopez, R; Oikonomou, I; Remzi, FH; Shen, B; Sherman, KK, 2007) |
| "Pouchitis is the most frequent long-term complication of IPAA in patients with UC, with a cumulative prevalence of up to 50%." | 2.46 | Diagnosis and management of pouchitis and ileoanal pouch dysfunction. ( Navaneethan, U; Shen, B, 2010) |
| "Collagenous colitis is characterised by watery diarrhoea, normal colonic mucosa on endoscopy, diffuse colitis with surface epithelial injury, and a distinctive thickening of the subepithelial collagen table on histology." | 1.33 | Collagenous pouchitis. ( Bennett, AE; Fazio, VW; Lashner, BA; Remzi, FH; Shen, B; Sherman, KK; Sun, J, 2006) |
| "Pouchitis is the most common long-term sequela of ileal pouch-anal anastomosis (IPAA) following total proctocolectomy." | 1.33 | Clostridium difficile-associated pouchitis. ( Bennett, AE; Fazio, VW; Goldblum, JR; Hull, TL; Remzi, FH; Shen, B, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Navaneethan, U | 1 |
| Shen, B | 4 |
| Bennett, AE | 3 |
| Fazio, VW | 3 |
| Sherman, KK | 2 |
| Sun, J | 1 |
| Remzi, FH | 3 |
| Lashner, BA | 2 |
| Goldblum, JR | 1 |
| Hull, TL | 1 |
| Lopez, R | 1 |
| Brzezinski, A | 1 |
| Oikonomou, I | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Pilot Study of the Safety and Efficacy of AST-120 in the Treatment of Active Pouchitis[NCT00583076] | Phase 2 | 19 participants (Actual) | Interventional | 2007-02-28 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for tinidazole and Pouch Ileitis
| Article | Year |
|---|---|
Diagnosis and management of pouchitis and ileoanal pouch dysfunction.
Topics: Adenomatous Polyposis Coli; Algorithms; Anti-Infective Agents; Antitrichomonal Agents; Ciprofloxacin | 2010 |
1 trial available for tinidazole and Pouch Ileitis
| Article | Year |
|---|---|
Combined ciprofloxacin and tinidazole therapy in the treatment of chronic refractory pouchitis.
Topics: Administration, Oral; Administration, Topical; Adult; Anti-Infective Agents; Chronic Disease; Ciprof | 2007 |
2 other studies available for tinidazole and Pouch Ileitis
| Article | Year |
|---|---|
Collagenous pouchitis.
Topics: Anal Canal; Anastomosis, Surgical; Anti-Bacterial Agents; Ciprofloxacin; Colitis, Collagenous; Endos | 2006 |
Clostridium difficile-associated pouchitis.
Topics: Anti-Infective Agents; Ciprofloxacin; Clostridioides difficile; Enterocolitis, Pseudomembranous; Hum | 2006 |