Page last updated: 2024-11-05

tinidazole and Neoplasms

tinidazole has been researched along with Neoplasms in 7 studies

Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" Teratogenicity tests in animals have given negative results in the case of metronidazole, ornidazole and tinidazole, and in the case of metronidazole no evidence of any adverse effect on the outcome of pregnancy was seen in women treated for trichomoniasis at various times during gestation, including the first trimester."3.67Safety of nitroimidazoles. ( Roe, FJ, 1985)
" The pharmacokinetic properties of tinidazole were studied by treating patients with 1."1.27Radiosensitization by tinidazole: pharmacokinetic study. ( Cossu, F; Facchini, A; Mazza, S; Rombi, GP, 1986)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lin, R1
Elf, S1
Shan, C1
Kang, HB1
Ji, Q1
Zhou, L1
Hitosugi, T1
Zhang, L1
Zhang, S1
Seo, JH1
Xie, J1
Tucker, M1
Gu, TL1
Sudderth, J1
Jiang, L1
Mitsche, M1
DeBerardinis, RJ1
Wu, S1
Li, Y1
Mao, H1
Chen, PR1
Wang, D1
Chen, GZ1
Hurwitz, SJ1
Lonial, S1
Arellano, ML1
Khoury, HJ1
Khuri, FR1
Lee, BH1
Lei, Q1
Brat, DJ1
Ye, K1
Boggon, TJ1
He, C1
Kang, S1
Fan, J1
Chen, J1
Lagast, H2
Klastersky, J3
Van Laethem, Y1
Coulter, JR1
Turner, JV1
Husson, M1
Weerts-Ruhl, D1
Daneau, D1
Cossu, F1
Rombi, GP1
Mazza, S1
Facchini, A1
Roe, FJ1

Reviews

1 review available for tinidazole and Neoplasms

ArticleYear
6-Phosphogluconate dehydrogenase links oxidative PPP, lipogenesis and tumour growth by inhibiting LKB1-AMPK signalling.
    Nature cell biology, 2015, Volume: 17, Issue:11

    Topics: AMP-Activated Protein Kinase Kinases; AMP-Activated Protein Kinases; Humans; Lipogenesis; Neoplasms;

2015

Trials

2 trials available for tinidazole and Neoplasms

ArticleYear
Anaerobic infections in cancer patients--a retrospective analysis of clindamycin, tinidazole, doxycycline, cefoxitin and lamoxactam.
    Infection, 1982, Volume: 10, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cefoxitin; Cephamycins; Clindamycin; Clinical Trials as

1982
Anaerobic wound infections in cancer patients: comparative trial of clindamycin, tinidazole, and doxycycline.
    Antimicrobial agents and chemotherapy, 1977, Volume: 12, Issue:5

    Topics: Anaerobiosis; Bacterial Infections; Clindamycin; Double-Blind Method; Doxycycline; Drug Resistance,

1977

Other Studies

4 other studies available for tinidazole and Neoplasms

ArticleYear
Anaerobic infections in cancer patients--comparison between therapy oriented strictly against anaerobes or both anaerobes and aerobes.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Aerobiosis; Anaerobiosis; Bacterial Infections; Female; Humans; Male; Middle Aged; Neoplasms; Tinida

1982
Treatment of amoebiasis and giardiasis.
    The Medical journal of Australia, 1978, Sep-09, Volume: 2, Issue:6

    Topics: Child; Dysentery, Amebic; Giardiasis; Humans; Metronidazole; Neoplasms; Nitroimidazoles; Research De

1978
Radiosensitization by tinidazole: pharmacokinetic study.
    International journal of clinical pharmacology research, 1986, Volume: 6, Issue:4

    Topics: Drug Administration Schedule; Humans; Kinetics; Neoplasms; Nitroimidazoles; Radiation-Sensitizing Ag

1986
Safety of nitroimidazoles.
    Scandinavian journal of infectious diseases. Supplementum, 1985, Volume: 46

    Topics: Abnormalities, Drug-Induced; Animals; Chromosome Aberrations; Cricetinae; Dose-Response Relationship

1985