Page last updated: 2024-11-05

tinidazole and Diarrhea

tinidazole has been researched along with Diarrhea in 21 studies

Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.

Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.

Research Excerpts

ExcerptRelevanceReference
"In random order, a single dose of either tinidazole or metronidazole, calculated as 50mg/kg body weight, was given to 100 children with symptomatic giardiasis."9.04Single dose therapy of giardiasis with tinidazole and metronidazole. ( Banerjee, M; Gazder, AJ, 1978)
"In random order, a single dose of either tinidazole or metronidazole, calculated as 50mg/kg body weight, was given to 100 children with symptomatic giardiasis."5.04Single dose therapy of giardiasis with tinidazole and metronidazole. ( Banerjee, M; Gazder, AJ, 1978)
" Giardia lamblia were found in nine patients and 15 patients responded to an empirical course of either metronidazole or tinidazole, without a positive diagnosis of giardiasis being made."3.66A prospective study of persistent diarrhoea. ( Bolin, TD; Davis, AE; Duncombe, VM, 1982)
"One of the principal features of AIDS in Africa is the diarrhea wasting syndrome known as "slim disease."2.67Chemotherapy of African AIDS diarrhoea: a preliminary study. ( Buve, A; Kelly, P, 1993)
"Giardiasis is an important cause of waterborne and foodborne diarrhea, daycare center outbreaks, and traveler's diarrhea."2.61Giardiasis: An Overview. ( Kam, JKM; Leung, AAM; Leung, AKC; Sergi, CM; Wong, AHC, 2019)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."2.49Amoebic dysentery. ( Marie, C; Petri, WA, 2013)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."2.47Amoebic dysentery. ( Mackey-Lawrence, NM; Petri, WA, 2011)
"Amoebic dysentery is caused by the protozoan parasite Entamoeba histolytica."2.44Amoebic dysentery. ( Dans, LF; Martínez, EG, 2007)

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19906 (28.57)18.7374
1990's1 (4.76)18.2507
2000's7 (33.33)29.6817
2010's7 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Subedi, Y1
Nissan, B1
Lachish, T1
Schwartz, E1
Sebastián Domingo, JJ1
Leung, AKC1
Leung, AAM1
Wong, AHC1
Sergi, CM1
Kam, JKM1
Marie, C1
Petri, WA2
Dans, LF1
Martínez, EG1
Escobedo, AA2
Almirall, P2
Alfonso, M1
Salazar, Y1
Avila, I1
Cimerman, S2
Núñez, FA1
Dawkins, IV1
Mackey-Lawrence, NM1
Ali, SA1
Hill, DR1
Alvarez, G1
González, ME1
Cañete, R1
Ruiz, A1
Pérez, R1
Bolin, TD1
Davis, AE1
Duncombe, VM1
Kelly, P1
Buve, A1
Calvet, X1
Titó, L1
Comet, R1
García, N1
Campo, R1
Brullet, E1
Armuzzi, A1
Cremonini, F1
Ojetti, V1
Bartolozzi, F1
Canducci, F1
Candelli, M1
Santarelli, L1
Cammarota, G1
De Lorenzo, A1
Pola, P1
Gasbarrini, G1
Gasbarrini, A1
Heering, NJ1
Gazder, AJ1
Banerjee, M1
Spech, HJ1
Salih, SY1
Abdalla, RE1
Holst-Larsen, L1
Chunge, CN1
Estambale, BB1
Pamba, HO1
Chitayi, PM1
Munanga, P1
Kangethe, S1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Phase 4, Prospective, Randomized and Comparative Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice[NCT01273441]Phase 4338 participants (Actual)Interventional2010-12-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

5 reviews available for tinidazole and Diarrhea

ArticleYear
Giardiasis: An Overview.
    Recent patents on inflammation & allergy drug discovery, 2019, Volume: 13, Issue:2

    Topics: Animals; Asymptomatic Diseases; Child; Clinical Trials as Topic; Diarrhea; Giardia; Giardiasis; Huma

2019
Amoebic dysentery.
    BMJ clinical evidence, 2013, Aug-30, Volume: 2013

    Topics: Administration, Oral; Diarrhea; Dysentery, Amebic; Entamoeba histolytica; Feces; Humans; Metronidazo

2013
Amoebic dysentery.
    BMJ clinical evidence, 2007, Jan-01, Volume: 2007

    Topics: Administration, Oral; Antibodies, Protozoan; Diarrhea; Dysentery, Amebic; Entamoeba histolytica; Fec

2007
Amoebic dysentery.
    BMJ clinical evidence, 2011, Jan-13, Volume: 2011

    Topics: Administration, Oral; Diarrhea; Dysentery, Amebic; Entamoeba histolytica; Humans; Incidence; Iodoqui

2011
Giardia intestinalis.
    Current opinion in infectious diseases, 2003, Volume: 16, Issue:5

    Topics: Animals; Antiprotozoal Agents; Diarrhea; Genotype; Giardia lamblia; Giardiasis; Humans; Ornidazole;

2003

Trials

5 trials available for tinidazole and Diarrhea

ArticleYear
The treatment of giardiasis in children: single-dose tinidazole compared with 3 days of nitazoxanide.
    Annals of tropical medicine and parasitology, 2008, Volume: 102, Issue:3

    Topics: Abdominal Pain; Adolescent; Antiparasitic Agents; Child; Child, Preschool; Cuba; Diarrhea; Feces; Fe

2008
Chemotherapy of African AIDS diarrhoea: a preliminary study.
    AIDS (London, England), 1993, Volume: 7, Issue:1

    Topics: Acquired Immunodeficiency Syndrome; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Di

1993
Four-day, twice daily, quadruple therapy with amoxicillin, clarithromycin, tinidazole and omeprazole to cure Helicobacter pylori infection: a pilot study.
    Helicobacter, 2000, Volume: 5, Issue:1

    Topics: Adult; Aged; Amoxicillin; Anti-Bacterial Agents; Anti-Ulcer Agents; Clarithromycin; Diarrhea; Drug A

2000
Effect of Lactobacillus GG supplementation on antibiotic-associated gastrointestinal side effects during Helicobacter pylori eradication therapy: a pilot study.
    Digestion, 2001, Volume: 63, Issue:1

    Topics: 2-Pyridinylmethylsulfinylbenzimidazoles; Adult; Anti-Bacterial Agents; Anti-Ulcer Agents; Benzimidaz

2001
Single dose therapy of giardiasis with tinidazole and metronidazole.
    Drugs, 1978, Volume: 15 Suppl 1

    Topics: Child; Child, Preschool; Diarrhea; Drug Administration Schedule; Feces; Female; Giardiasis; Humans;

1978

Other Studies

11 other studies available for tinidazole and Diarrhea

ArticleYear
Around Manaslu Ultramarathon: Diarrhea Is Still the King.
    Wilderness & environmental medicine, 2017, Volume: 28, Issue:4

    Topics: Acetaminophen; Acetazolamide; Altitude; Altitude Sickness; Analgesics, Non-Narcotic; Anti-Bacterial

2017
The effectiveness of empirical anti-parasitic treatment in returning travellers with persistent abdominal symptoms.
    Journal of travel medicine, 2018, Jan-01, Volume: 25, Issue:1

    Topics: Administration, Oral; Adolescent; Adult; Aged; Albendazole; Anthelmintics; Diarrhea; Drug Administra

2018
Irritable Bowel Syndrome with predominant diarrhea and giardiasis: is it one or the other?
    Gastroenterologia y hepatologia, 2018, Volume: 41, Issue:10

    Topics: Adult; Antiprotozoal Agents; Biopsy; Delayed Diagnosis; Diagnosis, Differential; Diarrhea; Duodenosc

2018
Hospitalization of Cuban children for giardiasis: a retrospective study in a paediatric hospital in Havana.
    Annals of tropical medicine and parasitology, 2011, Volume: 105, Issue:1

    Topics: Abdominal Pain; Antiprotozoal Agents; Child; Child, Preschool; Cuba; Diarrhea; Female; Giardiasis; H

2011
New drugs and dosage forms.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2004, Jul-15, Volume: 61, Issue:14

    Topics: Adolescent; Anti-Infective Agents; Antitrichomonal Agents; Apomorphine; Child; Contraindications; Di

2004
A prospective study of persistent diarrhoea.
    Australian and New Zealand journal of medicine, 1982, Volume: 12, Issue:1

    Topics: Adolescent; Adult; Aged; Colonic Diseases, Functional; Crohn Disease; Diarrhea; Female; Giardiasis;

1982
[Diarrhea due to a toxin of Clostridium difficile in hemato-oncological patients].
    Nederlands tijdschrift voor geneeskunde, 2001, Sep-08, Volume: 145, Issue:36

    Topics: Anti-Infective Agents; Bacterial Toxins; Clostridium Infections; Diarrhea; Dose-Response Relationshi

2001
[Lambliasis. Profile of a diarrheic disease].
    Deutsche medizinische Wochenschrift (1946), 1978, Dec-15, Volume: 103, Issue:50

    Topics: Biliary Tract Diseases; Diarrhea; Disease Outbreaks; Giardia; Giardiasis; Humans; Metronidazole; Nim

1978
Symptomatic giardiasis in Sudanese adults and its treatment with tinidazole.
    The Journal of tropical medicine and hygiene, 1977, Volume: 80, Issue:1

    Topics: Adolescent; Adult; Diarrhea; Female; Flatulence; Giardiasis; Humans; Male; Middle Aged; Nitroimidazo

1977
[Treatment of infections. Tourist diarrhea].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Mar-30, Volume: 96, Issue:9-10

    Topics: Bacterial Infections; Chloramphenicol; Chronic Disease; Diarrhea; Humans; Metronidazole; Tinidazole;

1976
Pathogenicity of Trichomonas hominis in Kenya.
    East African medical journal, 1988, Volume: 65, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Animals; Child; Diarrhea; Female; Humans; Kenya; Male; Tinidazole;

1988