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tinidazole and Bacterial Disease

tinidazole has been researched along with Bacterial Disease in 51 studies

Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.

Research Excerpts

ExcerptRelevanceReference
"Men with non-gonococcal urethritis (NGU) were divided into two groups and treated with either lymecycline or tinidazole; anaerobic cultures were performed before and after treatment."3.65The possible role of anaerobic bacteria in the aetiology of non-gonococcal urethritis in men. ( Hallén, A; Rydén, AC; Schwan, A; Wallin, J, 1977)
"Urinary tract infections were found in 10 placebo (20."2.66Single-dose intravenous tinidazole prophylaxis in abdominal hysterectomy. ( Evaldson, GR; Lindgren, S; Malmborg, AS; Nord, CE, 1986)
" The serum half-life values in the same order were 8."2.65The pharmacokinetics of one single preoperative dose of metronidazole or tinidazole. ( Bergan, T; Leinebø, O; Rosseland, AR; Solhaug, JH; Spada, L; Vaagenes, F, 1984)
"The pharmacokinetic properties of metronidazole (M) and tinidazole (T) were studied in patients undergoing colorectal surgery after a single preoperative dose of 1500 mg infused during 50 minutes."2.65Comparative pharmacokinetics of metronidazole and tinidazole used as single dose prophylactic agents. ( Bakkevold, K; Bergan, T; Leinebø, O; Salvesen, B; Søreide, O; Ulvik, NM, 1984)
" The prophylactic regimens significantly reduced the infectious complications, as evidenced by fewer infections, less total antibiotic dosage and shorter hospitalization."2.65Short term chemotherapeutic prophylaxis in gastrointestinal operations. ( Bergan, T; Christiansen, E; Fuglesang, J; Giercksky, KE; Johnson, JA, 1980)
"Tinidazole is a versatile anti-amoebic and anti-anaerobic drug used in treatment of intestinal infection."1.43Development of microbial trigger based oral formulation of Tinidazole and its Gamma Scintigraphy Evaluation: A promising tool against anaerobic microbes associated GI problems. ( Bhatnagar, A; Khare, NK; Kumar, N; Nishad, DK; Sharma, BG, 2016)
" However, extreme caution in their long-term use and use in obstetric and paediatric patients should be exercised until toxicological issues are resolved."1.27Current clinical applications and dose regimens of metronidazole and related nitroimidazoles. ( Ioannides-Demos, LL; McLean, AJ; Spicer, WJ, 1984)

Research

Studies (51)

TimeframeStudies, this research(%)All Research%
pre-199045 (88.24)18.7374
1990's2 (3.92)18.2507
2000's2 (3.92)29.6817
2010's2 (3.92)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ang, CW1
Jarrad, AM1
Cooper, MA1
Blaskovich, MAT1
Sharma, BG1
Kumar, N1
Nishad, DK1
Khare, NK1
Bhatnagar, A1
Iakovlev, VP1
Blatun, LA1
Terekhova, RP1
Sud, B1
Salvaggio, M1
Greenfield, R1
Greenfield, RA1
Bronze, MS1
McDonald, PJ1
Sanders, T1
Higgins, G1
Finlay-Jones, L1
Hakendorf, M1
Turnidge, J1
Jones, W1
Lagast, H2
Klastersky, J3
Ivchenko, VN1
Mel'nik, VM1
Lafaix, C1
Langlois, O1
Zrubek, H1
Szymański, CZ1
Czajka, R1
Oleszczuk, J1
Tunér, K1
Nord, CE5
Skarin, A1
Holst, E1
Mårdh, PA1
Solhaug, JH1
Bergan, T3
Leinebø, O2
Rosseland, AR1
Spada, L1
Vaagenes, F1
Søreide, O1
Bakkevold, K1
Salvesen, B1
Ulvik, NM1
Cho, N2
Fukunaga, K2
Kunii, K2
Deguchi, K2
McLean, AJ1
Ioannides-Demos, LL1
Spicer, WJ1
Carmine, AA1
Brogden, RN1
Heel, RC1
Speight, TM1
Avery, GS1
Packard, RS1
Nordbring, F1
Jokipii, AM2
Jokipii, L2
Kuhn, RJ1
Salo, J1
Silvennoinen, E1
Hulkko, A1
Ervasti, E1
Holopainen, O1
Lahnborg, G1
Giamarellou, H1
Gazis, J1
Vlachos, G1
Michalopoulos, A1
Aravantinos, P1
Daikos, GK1
Van Laethem, Y1
Mattie, H1
Dijkmans, BA1
van Gulpen, C1
Eibach, HW1
Karhunen, M4
Koskela, O4
Hannelin, M2
Hällström, K1
Appelbaum, PC1
Moodley, J1
Chatterton, SA1
Cowan, DB1
Africa, CW1
Giercksky, KE1
Fuglesang, J1
Christiansen, E1
Johnson, JA1
Vutyavanich, T1
Pongsuthirak, P1
Vannareumol, P1
Ruangsri, RA1
Luangsook, P1
Adno, J1
Cassel, R1
Hallén, A1
Rydén, AC1
Schwan, A1
Wallin, J1
Myllylä, VV1
Hokkanen, E1
Husson, M1
Weerts-Ruhl, D1
Daneau, D1
Holst-Larsen, L1
Brismar, B1
Edlund, C1
Malmborg, AS2
Heikkinen, J1
Vuopala, S1
Evaldson, GR1
Lindgren, S1
Teisala, K1
Suikkari, AM1
Mattila, J1

Reviews

7 reviews available for tinidazole and Bacterial Disease

ArticleYear
Nitroimidazoles: Molecular Fireworks That Combat a Broad Spectrum of Infectious Diseases.
    Journal of medicinal chemistry, 2017, 09-28, Volume: 60, Issue:18

    Topics: Animals; Anti-Infective Agents; Bacteria; Bacterial Infections; Communicable Diseases; Humans; Nitro

2017
Part XI. Trimethoprim-sulfamethoxazole, nitrofurantoin, chloramphenicol, metronidazole and tinidazole, rifaximin, and nitazoxanide.
    The Journal of the Oklahoma State Medical Association, 2007, Volume: 100, Issue:7

    Topics: Anti-Bacterial Agents; Bacterial Infections; Chloramphenicol; Drug Resistance, Microbial; Humans; Me

2007
[Use of metronidazole and its analogs in surgery].
    Klinicheskaia khirurgiia, 1983, Issue:1

    Topics: Bacteria; Bacterial Infections; DNA, Bacterial; Female; Gram-Negative Anaerobic Bacteria; Humans; In

1983
Tinidazole in anaerobic infections: a review of its antibacterial activity, pharmacological properties and therapeutic efficacy.
    Drugs, 1982, Volume: 24, Issue:2

    Topics: Anaerobiosis; Animals; Bacteria; Bacterial Infections; Humans; Kinetics; Nitroimidazoles; Postoperat

1982
Tinidazole: a review of clinical experience in anaerobic infections.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Administration, Oral; Anaerobiosis; Bacterial Infections; Female; Gastrointestinal Diseases; Genital

1982
Aspects on antibacterial treatment of anaerobic infections.
    Scandinavian journal of infectious diseases. Supplementum, 1982, Volume: 35

    Topics: Anaerobiosis; Anti-Bacterial Agents; Bacterial Infections; Bacteroides fragilis; Bacteroides Infecti

1982
Ecological impact of antimicrobial prophylaxis on intestinal microflora in patients undergoing colorectal surgery.
    Scandinavian journal of infectious diseases. Supplementum, 1990, Volume: 70

    Topics: 4-Quinolones; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Clindamycin; Colon; Humans; Int

1990

Trials

26 trials available for tinidazole and Bacterial Disease

ArticleYear
[Clinical efficacy of a novel antimicrobial drug combination containing ciprofloxacin and tinidazole in the treatment of patients with skin and soft tissue infections].
    Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic], 2005, Volume: 50, Issue:2-3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Bacterial Agents; Bacterial Infections; Ciprofloxacin; Drug Com

2005
Antibiotic prophylaxis in hysterectomy--cefotaxime compared to ampicillin-tinidazole.
    The Journal of antimicrobial chemotherapy, 1984, Volume: 14 Suppl B

    Topics: Adult; Ampicillin; Bacterial Infections; Cefotaxime; Drug Combinations; Female; Humans; Hysterectomy

1984
Anaerobic infections in cancer patients--a retrospective analysis of clindamycin, tinidazole, doxycycline, cefoxitin and lamoxactam.
    Infection, 1982, Volume: 10, Issue:3

    Topics: Anti-Bacterial Agents; Bacterial Infections; Cefoxitin; Cephamycins; Clindamycin; Clinical Trials as

1982
[Comparative study of tinidazole and ornidazole for the prevention of septic complications of colonic surgery].
    Pathologie-biologie, 1983, Volume: 31, Issue:6

    Topics: Bacterial Infections; Colon; Female; Humans; Male; Middle Aged; Nitroimidazoles; Ornidazole; Postope

1983
[Evaluation of the validity of the preventive use of metronidazole and tinidazole in surgery of the genital organs].
    Ginekologia polska, 1984, Volume: 55, Issue:11

    Topics: Adult; Bacterial Infections; Clinical Trials as Topic; Female; Genital Diseases, Female; Humans; Met

1984
The pharmacokinetics of one single preoperative dose of metronidazole or tinidazole.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 90

    Topics: Aged; Bacterial Infections; Chromatography, High Pressure Liquid; Colon; Female; Half-Life; Humans;

1984
Comparative pharmacokinetics of metronidazole and tinidazole used as single dose prophylactic agents.
    Scandinavian journal of gastroenterology. Supplement, 1984, Volume: 90

    Topics: Adult; Aged; Bacterial Infections; Chromatography, High Pressure Liquid; Colon; Female; Half-Life; H

1984
Chemoprophylaxis with tinidazole in major gynaecological surgery.
    The Australian & New Zealand journal of obstetrics & gynaecology, 1980, Volume: 20, Issue:1

    Topics: Bacterial Infections; Clinical Trials as Topic; Double-Blind Method; Female; Fever; Humans; Hysterec

1980
Tinidazole in the prophylaxis of post-appendicectomy infections.
    Annales chirurgiae et gynaecologiae, 1981, Volume: 70, Issue:4

    Topics: Adult; Anti-Infective Agents; Appendectomy; Bacterial Infections; Clinical Trials as Topic; Female;

1981
The pharmacokinetics of metronidazole and tinidazole in patients with mixed aerobic--anaerobic infections.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Administration, Oral; Adolescent; Adult; Aerobiosis; Aged; Anaerobiosis; Bacterial Infections; Chrom

1982
[Single dose of tinidazole in prevention of post-hysterectomy infections].
    Duodecim; laaketieteellinen aikakauskirja, 1980, Volume: 96, Issue:17

    Topics: Adult; Bacterial Infections; Drug Resistance, Microbial; Female; Humans; Hysterectomy; Metronidazole

1980
Single dose of tinidazole in prophylaxis in infections following vaginal surgery.
    The Journal of antimicrobial chemotherapy, 1981, Volume: 8, Issue:4

    Topics: Bacterial Infections; Bacteroides; Female; Humans; Hysterectomy, Vaginal; Nitroimidazoles; Postopera

1981
Short term chemotherapeutic prophylaxis in gastrointestinal operations.
    Surgery, gynecology & obstetrics, 1980, Volume: 151, Issue:3

    Topics: Adult; Anti-Bacterial Agents; Bacterial Infections; Clindamycin; Digestive System Surgical Procedure

1980
A randomized double-blind trial of tinidazole treatment of the sexual partners of females with bacterial vaginosis.
    Obstetrics and gynecology, 1993, Volume: 82, Issue:4 Pt 1

    Topics: Adolescent; Adult; Bacterial Infections; Double-Blind Method; Female; Follow-Up Studies; Humans; Mal

1993
The effect of prophylactic tinidazole on the anaerobic vaginal flora in patients undergoing gynaecological surgery.
    South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1979, Sep-29, Volume: 56, Issue:14

    Topics: Bacterial Infections; Cervix Uteri; Double-Blind Method; Drug Evaluation; Enterococcus faecalis; Fem

1979
Anaerobic wound infections in cancer patients: comparative trial of clindamycin, tinidazole, and doxycycline.
    Antimicrobial agents and chemotherapy, 1977, Volume: 12, Issue:5

    Topics: Anaerobiosis; Bacterial Infections; Clindamycin; Double-Blind Method; Doxycycline; Drug Resistance,

1977
Anaerobic vaginosis: treatment with tinidazole vaginal tablets.
    Gynecologic and obstetric investigation, 1989, Volume: 28, Issue:2

    Topics: Adult; Bacteria, Anaerobic; Bacterial Infections; Female; Humans; Intrauterine Devices; Middle Aged;

1989
Clinical trial of prophylaxis of wound sepsis in elective colorectal surgery comparing ticarcillin with tinidazole. University of Melbourne Colorectal Group.
    The Australian and New Zealand journal of surgery, 1986, Volume: 56, Issue:3

    Topics: Administration, Oral; Aged; Analysis of Variance; Bacterial Infections; Bacteroides Infections; Clin

1986
Infectious problems in elective colorectal surgery: a multi-centre study. The Norwegian Gastro-Intestinal Group (NORGAS).
    Current medical research and opinion, 1988, Volume: 11, Issue:3

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Child; Colonic Diseases; Doxycycli

1988
Infectious problems in elective surgery of the alimentary tract: the influence of pre-operative factors. The Norwegian Gastro-Intestinal Group (NORGAS).
    Current medical research and opinion, 1988, Volume: 11, Issue:3

    Topics: Abdomen; Bacterial Infections; Blood Pressure; Doxycycline; Drug Therapy, Combination; Female; Gastr

1988
Infectious problems in elective non-colorectal abdominal surgery. The Norwegian Gastro-Intestinal Group (NORGAS).
    Current medical research and opinion, 1988, Volume: 11, Issue:3

    Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Biliary Tract Diseases; C

1988
Infectious problems after elective surgery of the alimentary tract: the influence of peri-operative factors. The Norwegian Gastro-Intestinal Group (NORGAS).
    Current medical research and opinion, 1988, Volume: 11, Issue:3

    Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Blood Transfusion; Child;

1988
Critical care requirements after elective surgery of the alimentary tract. The Norwegian Gastro-Intestinal Group (NORGAS).
    Current medical research and opinion, 1988, Volume: 11, Issue:3

    Topics: Abdomen; Adolescent; Adult; Aged; Aged, 80 and over; Bacterial Infections; Child; Critical Care; Dox

1988
Single-dose intravenous tinidazole prophylaxis in abdominal hysterectomy.
    Acta obstetricia et gynecologica Scandinavica, 1986, Volume: 65, Issue:4

    Topics: Abscess; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Double-Blind Method; Female; H

1986
Should antimicrobial prophylaxis in colorectal surgery include agents effective against both anaerobic and aerobic microorganisms? A double-blind, multicenter study. The Norwegian Study Group for Colorectal Surgery.
    Surgery, 1985, Volume: 97, Issue:4

    Topics: Adolescent; Adult; Aged; Bacteria, Aerobic; Bacteria, Anaerobic; Bacterial Infections; Clinical Tria

1985
Prophylaxis and treatment of anaerobic infections following caesarean section with tinidazole.
    Chemotherapy, 1985, Volume: 31, Issue:3

    Topics: Adult; Amniotic Fluid; Anaerobiosis; Bacterial Infections; Cesarean Section; Double-Blind Method; En

1985

Other Studies

18 other studies available for tinidazole and Bacterial Disease

ArticleYear
Development of microbial trigger based oral formulation of Tinidazole and its Gamma Scintigraphy Evaluation: A promising tool against anaerobic microbes associated GI problems.
    European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences, 2016, Jun-30, Volume: 89

    Topics: Adult; Bacteria, Anaerobic; Bacterial Infections; Bacteroides fragilis; Chemistry, Pharmaceutical; D

2016
Betalactamase-producing microorganisms in recurrent tonsillitis.
    Scandinavian journal of infectious diseases. Supplementum, 1983, Volume: 39

    Topics: Adolescent; Adult; Bacteria; Bacterial Infections; beta-Lactamases; Clindamycin; Humans; Nitroimidaz

1983
Antimicrobial susceptibility of comma-shaped bacteria isolated from the vagina.
    Scandinavian journal of infectious diseases. Supplementum, 1983, Volume: 40

    Topics: Anti-Bacterial Agents; Bacterial Infections; Culture Media; Drug Resistance, Microbial; Female; Gram

1983
Tinidazole v. metronidazole.
    Drug and therapeutics bulletin, 1983, Nov-18, Volume: 21, Issue:23

    Topics: Bacteria, Anaerobic; Bacterial Infections; Humans; Metronidazole; Nitroimidazoles; Protozoan Infecti

1983
[Clinical evaluation of tinidazole on anaerobic infections in the field of obstetrics and gynecology].
    The Japanese journal of antibiotics, 1983, Volume: 36, Issue:12

    Topics: Adult; Bacteria, Anaerobic; Bacterial Infections; Drug Evaluation; Drug Resistance, Microbial; Femal

1983
Current clinical applications and dose regimens of metronidazole and related nitroimidazoles.
    The Medical journal of Australia, 1984, Aug-04, Volume: 141, Issue:3

    Topics: Administration, Oral; Bacterial Infections; Dose-Response Relationship, Drug; Drug Administration Sc

1984
Metronidazole, tinidazole, ornidazole and anaerobic infections of the middle ear, maxillary sinus and central nervous system.
    Scandinavian journal of infectious diseases. Supplementum, 1981, Volume: 26

    Topics: Bacterial Infections; Central Nervous System Diseases; Humans; Maxillary Sinus; Metronidazole; Nitro

1981
Anaerobic infections: the role of tinidazole. Proceedings of a symposium: Edinburgh, Scotland, 19 and 20 April 1982.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Anaerobiosis; Bacterial Infections; Humans; Nitroimidazoles; Tinidazole

1982
Efficacy of tinidazole compared to clindamycin in the treatment of experimentally induced intra-abdominal sepsis.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Abdomen; Animals; Bacterial Infections; Clindamycin; Drug Therapy, Combination; Male; Netilmicin; Ni

1982
Tinidazole in the treatment of surgical and gynaecological infections.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Adult; Aged; Aminoglycosides; Anaerobiosis; Anti-Bacterial Agents; Bacterial Infections; Female; Gen

1982
Anaerobic infections in cancer patients--comparison between therapy oriented strictly against anaerobes or both anaerobes and aerobes.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Aerobiosis; Anaerobiosis; Bacterial Infections; Female; Humans; Male; Middle Aged; Neoplasms; Tinida

1982
Tinidazole for the treatment of anaerobic gynaecological infections.
    The Journal of antimicrobial chemotherapy, 1982, Volume: 10 Suppl A

    Topics: Adolescent; Adult; Anaerobiosis; Bacterial Infections; Female; Genital Diseases, Female; Humans; Inf

1982
[The effect of tinidazole on the anaerobic bacterial flora in patients undergoing gynecological surgery].
    The Japanese journal of antibiotics, 1982, Volume: 35, Issue:7

    Topics: Bacteria; Bacterial Infections; Drug Administration Schedule; Drug Evaluation; Drug Resistance, Micr

1982
Single dose of tinidazole in prophylaxis of infections following hysterectomy.
    British journal of obstetrics and gynaecology, 1980, Volume: 87, Issue:1

    Topics: Adult; Bacterial Infections; Drug Administration Schedule; Female; Humans; Hysterectomy; Middle Aged

1980
Tinidazole in the prophylaxis and treatment of anaerobic infection.
    Chemotherapy, 1980, Volume: 26, Issue:2

    Topics: Anaerobiosis; Bacterial Infections; Female; Humans; Nitroimidazoles; Postoperative Complications; Ti

1980
The possible role of anaerobic bacteria in the aetiology of non-gonococcal urethritis in men.
    The British journal of venereal diseases, 1977, Volume: 53, Issue:6

    Topics: Adult; Anaerobiosis; Bacterial Infections; Humans; Lymecycline; Male; Tinidazole; Urethritis

1977
Penetration of the blood brain barrier by metronidazole and tinidazole.
    The Journal of antimicrobial chemotherapy, 1977, Volume: 3, Issue:3

    Topics: Animals; Bacterial Infections; Bacteroides Infections; Blood-Brain Barrier; Central Nervous System D

1977
[Treatment of infections. Tourist diarrhea].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1976, Mar-30, Volume: 96, Issue:9-10

    Topics: Bacterial Infections; Chloramphenicol; Chronic Disease; Diarrhea; Humans; Metronidazole; Tinidazole;

1976