Page last updated: 2024-11-05

tinidazole and Abscess, Amebic

tinidazole has been researched along with Abscess, Amebic in 14 studies

Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.

Research Excerpts

ExcerptRelevanceReference
"Intestinal amoebiasis: of 502 patients, comprising 458 adults and 44 children, with symptomatic intestinal amoebiasis who received tinidazole as a single daily dose on 2 to 3 consecutive days, 477 (95%) were parasitologically cured with complete or marked improvement in symptoms."5.26Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study. ( Apte, VV; Packard, RS, 1978)
"We describe a patient with a liver abscess due to Entamoeba histolytica, in whom metronidazole therapy (total dose, 21 g over 14 days) was complicated by reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess."3.69Amebic abscess of the spleen complicated by metronidazole-induced neurotoxicity: case report. ( Lawford, R; Sorrell, TC, 1994)
"Tinidazole, a synthetic imidazole derivative, has been used in the oral treatment of several protozoal infections - trichomoniasis, giardiasis and amoebiasis."3.65Tinidazole: a review of its antiprotozoal activity and therapeutic efficacy. ( Avery, GS; Brogden, RN; Pinder, RM; Sawyer, PR; Speight, TM, 1976)
" We cannot, therefore, recommend tinidazole alone in this dosage as a treatment for non-invasive amoebiasis."2.65Treatment of non-invasive amoebiasis. A comparison between tinidazole alone and in combination with diloxanide furoate. ( Bengtsson, E; Pehrson, P, 1983)
"Intestinal amoebiasis: of 502 patients, comprising 458 adults and 44 children, with symptomatic intestinal amoebiasis who received tinidazole as a single daily dose on 2 to 3 consecutive days, 477 (95%) were parasitologically cured with complete or marked improvement in symptoms."1.26Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study. ( Apte, VV; Packard, RS, 1978)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's1 (7.14)18.2507
2000's2 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fabio, PF1
Fields, TL1
Lin, Y1
Burden, EJ1
Carvajal, S1
Murdock, KC1
Lang, SA1
Manes, G1
Balzano, A1
van Hal, SJ1
Stark, DJ1
Fotedar, R1
Marriott, D1
Ellis, JT1
Harkness, JL1
Knight, R1
Pehrson, P1
Bengtsson, E1
Rossignol, JF1
Maisonneuve, H1
Cho, YW1
Coulaud, JP1
Mechali, D1
Lawford, R1
Sorrell, TC1
Spillmann, R1
Ayala, SC1
Sanchez, CE1
Bakshi, JS1
Ghiara, JM1
Nanivadekar, AS1
Apte, VV1
Packard, RS1
Sawyer, PR1
Brogden, RN1
Pinder, RM1
Speight, TM1
Avery, GS1
Saif, M1
Koura, M1
Ashmawy, H1
Gaber, A1
Abdel-Meguid, M1
Bhandari, B1
Mandowara, SL1

Reviews

2 reviews available for tinidazole and Abscess, Amebic

ArticleYear
Tinidazole: from protozoa to Helicobacter pylori--the past, present and future of a nitroimidazole with peculiarities.
    Expert review of anti-infective therapy, 2004, Volume: 2, Issue:5

    Topics: Amebiasis; Animals; Anti-Bacterial Agents; Antibiotic Prophylaxis; Antitrichomonal Agents; Clinical

2004
Amoebiasis: current status in Australia.
    The Medical journal of Australia, 2007, Apr-16, Volume: 186, Issue:8

    Topics: Amebiasis; Amebicides; Animals; Australia; Emigration and Immigration; Entamoeba histolytica; Humans

2007

Trials

3 trials available for tinidazole and Abscess, Amebic

ArticleYear
Treatment of non-invasive amoebiasis. A comparison between tinidazole alone and in combination with diloxanide furoate.
    Transactions of the Royal Society of Tropical Medicine and Hygiene, 1983, Volume: 77, Issue:6

    Topics: Adolescent; Adult; Aged; Amebiasis; Amebicides; Child; Drug Therapy, Combination; Furans; Humans; Mi

1983
Double-blind test of metronidazole and tinidazole in the treatment of asymptomatic Entamoeba histolytica and Entamoeba hartmanni carriers.
    The American journal of tropical medicine and hygiene, 1976, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Aged; Amebiasis; Carrier State; Child; Clinical Trials as Topic; Entamoeba; Entam

1976
How does tinidazole compare with metronidazole? A summary report of Indian trials in amoebiasis and giardiasis.
    Drugs, 1978, Volume: 15 Suppl 1

    Topics: Adult; Amebiasis; Child; Clinical Trials as Topic; Dysentery, Amebic; Female; Giardiasis; Humans; In

1978

Other Studies

9 other studies available for tinidazole and Abscess, Amebic

ArticleYear
Bisamidines of 2,6-diaminoanthraquinone as antiamebic agents.
    Journal of medicinal chemistry, 1978, Volume: 21, Issue:3

    Topics: Amebiasis; Amebicides; Amidines; Animals; Anthraquinones; Cricetinae; Dysentery, Amebic; Entamoeba h

1978
The chemotherapy of amoebiasis.
    The Journal of antimicrobial chemotherapy, 1980, Volume: 6, Issue:5

    Topics: Acetanilides; Amebiasis; Amebicides; Arsenicals; Carrier State; Chloroquine; Dysentery, Amebic; Emet

1980
Nitroimidazoles in the treatment of trichomoniasis, giardiasis, and amebiasis.
    International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:2

    Topics: Amebiasis; Animals; Chemical Phenomena; Chemistry; Cricetinae; Female; Giardiasis; Humans; Metronida

1984
[Treatment of amebiasis].
    Soins. Pathologie tropicale, 1981, Issue:29

    Topics: Amebiasis; Emetine; Humans; Metronidazole; Tinidazole

1981
Amebic abscess of the spleen complicated by metronidazole-induced neurotoxicity: case report.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 19, Issue:2

    Topics: Adult; Amebiasis; Ataxia; Central Nervous System Diseases; Humans; Liver Abscess, Amebic; Male; Metr

1994
Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study.
    Drugs, 1978, Volume: 15 Suppl 1

    Topics: Adult; Amebiasis; Child; Dysentery, Amebic; Giardiasis; Humans; Liver Abscess, Amebic; Nitroimidazol

1978
Tinidazole: a review of its antiprotozoal activity and therapeutic efficacy.
    Drugs, 1976, Volume: 11, Issue:6

    Topics: Abnormalities, Drug-Induced; Amebiasis; Animals; Eukaryota; Giardiasis; Gonorrhea; Humans; Kinetics;

1976
Tinidazole therapy in lambliasis and amoebiasis.
    The Journal of the Egyptian Medical Association, 1976, Volume: 59, Issue:7-12

    Topics: Adolescent; Adult; Amebiasis; Female; Giardiasis; Humans; Intestinal Diseases, Parasitic; Male; Midd

1976
Rectal prolapse.
    Indian pediatrics, 1985, Volume: 22, Issue:6

    Topics: Amebiasis; Child; Child, Preschool; Dysentery, Bacillary; Humans; Infant; Infant, Newborn; Iodoquino

1985