tinidazole has been researched along with Abscess, Amebic, Hepatic in 34 studies
Tinidazole: A nitroimidazole alkylating agent that is used as an antitrichomonal agent against TRICHOMONAS VAGINALIS; ENTAMOEBA HISTOLYTICA; and GIARDIA LAMBLIA infections. It also acts as an antibacterial agent for the treatment of BACTERIAL VAGINOSIS and anaerobic bacterial infections.
tinidazole : 1H-imidazole substituted at C-1 by a (2-ethylsulfonyl)ethyl group, at C-2 by a methyl group and at C-5 by a nitro group. It is used as an antiprotozoal, antibacterial agent.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intestinal amoebiasis: of 502 patients, comprising 458 adults and 44 children, with symptomatic intestinal amoebiasis who received tinidazole as a single daily dose on 2 to 3 consecutive days, 477 (95%) were parasitologically cured with complete or marked improvement in symptoms." | 5.26 | Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study. ( Apte, VV; Packard, RS, 1978) |
| "We describe a patient with a liver abscess due to Entamoeba histolytica, in whom metronidazole therapy (total dose, 21 g over 14 days) was complicated by reversible deafness, tinnitus, and ataxia and who relapsed 5 months later with a splenic abscess." | 3.69 | Amebic abscess of the spleen complicated by metronidazole-induced neurotoxicity: case report. ( Lawford, R; Sorrell, TC, 1994) |
| "Metronidazole is a drug of choice for amebic liver abscess (ALA), but has long course and significant side effects." | 2.87 | Comparative study of tinidazole versus metronidazole in treatment of amebic liver abscess: A randomized control trial. ( Gupta, GK; Nijhawan, S; Pandey, S; Wanjari, SJ, 2018) |
| "Thirty-six patients with uncomplicated amoebic liver abscess were treated with low dose tinidazole 1." | 2.66 | Low dose tinidazole in the treatment of amoebic liver abscess. ( Bunnag, D; Harinasuta, T; Looareesuwan, S; Vanijanonta, S, 1985) |
| "Forty-eight patients were treated for amoebic liver abscess, 27 with metronidazole (Flagyl; Maybaker) and 21 with tinidazole (Fasigyn; Pfizer)." | 2.66 | A comparative trial of metronidazole v. tinidazole in the treatment of amoebic liver abscess. ( Gathiram, V; Jackson, TF; Khan, BF; Simjee, AE, 1985) |
| "Ten patients suffering from amoebic liver abscess were treated with tinidazole (Fasigyn) 800 mg t." | 2.64 | Tinidazole for the treatment of amoebic liver abscess. ( Hatchuel, W, 1975) |
| "Twenty proven cases of amoebic liver abscess were treated at random with either tinidazole or metronidazole." | 2.64 | Comparative study of tinidazole and metronidazole in amoebic liver abscess. ( Damle, VB; Deodhar, KP; Garud, AD; Khokhani, RC; Kulkarni, M; Sureka, SB, 1977) |
| "20 patients with amoebic liver abscess, confirmed by aspiration of typical amoebic 'pus', were treated in random order with either tinidazole or metronidazole in a dose of 2g once daily for 2 days." | 2.64 | Treatment of amoebic liver abscess with tinidazole and metronidazole. ( Damle, VB; Deodhar, KP; Garud, AD; Khokhani, RC; Kulkarni, M; Sureka, SB, 1978) |
| "In this study of hepatic amoebiasis in Bangladesh, tinidazole was found to be superior to metronidazole in overall efficacy because a shorter course of treatment was necessary and it caused fewer side-effects." | 2.64 | Tinidazole and metronidazole in hepatic amoebiasis. ( Hasan, K; Islam, N, 1978) |
| "Hepatitis A virus (HAV) infection and amoebic liver abscess have an identical mode of transmission (fecal-oral route) and similar epidemiology." | 1.30 | Simultaneous amoebic liver abscess and hepatitis A infection. ( Piper-Jenks, N; Schwartz, E, 1998) |
| "Ten cases of hepatic amoebiasis are notified in Bamako during 14 months among hospitalized adults." | 1.28 | [Short treatment of hepatic amebiasis by tinidazole. Apropos of 10 cases]. ( Dembele, M; Doumbo, O; Keita, A; Pène, P; Pichard, E; Traore, HA, 1991) |
| "Tinidazole is a noteworthy addition to anti-amoebic therapy." | 1.26 | Tinidazole and metronidazole in the treatment of amoebic liver abscess. ( Itigi, A; Mathur, SN; Rai, V, 1977) |
| " However, in 7 cases the dosage had to be repeated." | 1.26 | Amoebic liver abscess and clinical experiences with tinidazole in Bangladesh. ( Islam, N; Quaderi, MA; Rahman, A; Rahman, MS, 1978) |
| "Intestinal amoebiasis: of 502 patients, comprising 458 adults and 44 children, with symptomatic intestinal amoebiasis who received tinidazole as a single daily dose on 2 to 3 consecutive days, 477 (95%) were parasitologically cured with complete or marked improvement in symptoms." | 1.26 | Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study. ( Apte, VV; Packard, RS, 1978) |
| "Of 25 children with amoebic liver abscess, 23 were cured." | 1.26 | Tinidazole in treatment of amoebic liver abscess in children. ( Proctor, EM; Scragg, JN, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 23 (67.65) | 18.7374 |
| 1990's | 6 (17.65) | 18.2507 |
| 2000's | 1 (2.94) | 29.6817 |
| 2010's | 3 (8.82) | 24.3611 |
| 2020's | 1 (2.94) | 2.80 |
| Authors | Studies |
|---|---|
| Fabio, PF | 1 |
| Fields, TL | 1 |
| Lin, Y | 1 |
| Burden, EJ | 1 |
| Carvajal, S | 1 |
| Murdock, KC | 1 |
| Lang, SA | 1 |
| Singh, A | 1 |
| Banerjee, T | 1 |
| Shukla, SK | 1 |
| Upadhyay, S | 1 |
| Verma, A | 1 |
| Pandey, S | 1 |
| Gupta, GK | 1 |
| Wanjari, SJ | 1 |
| Nijhawan, S | 1 |
| Hwang, EW | 1 |
| Cheung, L | 1 |
| Mojtahed, A | 1 |
| Cartwright, CA | 1 |
| Hung, CC | 1 |
| Chang, SY | 1 |
| Ji, DD | 1 |
| Wolfe, MS | 1 |
| Mendis, S | 1 |
| Dharmasena, BD | 1 |
| Jayatissa, SK | 1 |
| Lasserre, R | 1 |
| Jaroonvesama, N | 1 |
| Kurathong, S | 1 |
| Soh, CT | 1 |
| Lawford, R | 1 |
| Sorrell, TC | 1 |
| García-Forcada, A | 1 |
| Sans, M | 1 |
| Gascón, J | 1 |
| Valls, ME | 1 |
| Bru, C | 1 |
| Corachán, M | 1 |
| Schwartz, E | 1 |
| Piper-Jenks, N | 1 |
| Mizuno, Y | 1 |
| Mori, M | 1 |
| Ohba, K | 1 |
| Kumada, K | 1 |
| Owaki, T | 1 |
| Kamiya, S | 1 |
| Kawai, H | 1 |
| Spicer, PE | 1 |
| Clapham, G | 1 |
| Ambroise-Thomas, P | 1 |
| Meyer, HA | 2 |
| Hatchuel, W | 1 |
| Khokhani, RC | 2 |
| Garud, AD | 2 |
| Deodhar, KP | 2 |
| Sureka, SB | 2 |
| Kulkarni, M | 2 |
| Damle, VB | 2 |
| Islam, N | 3 |
| Hasan, K | 1 |
| Bakshi, JS | 1 |
| Ghiara, JM | 1 |
| Nanivadekar, AS | 1 |
| Mathur, SN | 1 |
| Itigi, A | 1 |
| Rai, V | 1 |
| Kundu, SC | 1 |
| Sen, A | 1 |
| Bhattacherjee, TD | 1 |
| Dasgupta, DP | 1 |
| Majumdar, S | 1 |
| Moorkerjee, PK | 1 |
| Mukerjee, AB | 1 |
| Quaderi, MA | 1 |
| Rahman, MS | 1 |
| Rahman, A | 1 |
| Hasan, M | 1 |
| Apte, VV | 1 |
| Packard, RS | 1 |
| Ohn, KM | 1 |
| Thwe, M | 1 |
| Abiose, PA | 1 |
| Olupitan, SB | 1 |
| Yousuf, M | 1 |
| Scragg, JN | 1 |
| Proctor, EM | 1 |
| Pichard, E | 1 |
| Traore, HA | 1 |
| Keita, A | 1 |
| Dembele, M | 1 |
| Doumbo, O | 1 |
| Pène, P | 1 |
| Antón Aranda, E | 1 |
| Cía, MT | 1 |
| Celador Almaraz, A | 1 |
| Uribarrena Echeverría, R | 1 |
| Rivero Puente, A | 1 |
| Vanijanonta, S | 1 |
| Bunnag, D | 1 |
| Looareesuwan, S | 1 |
| Harinasuta, T | 1 |
| Simjee, AE | 1 |
| Gathiram, V | 1 |
| Jackson, TF | 1 |
| Khan, BF | 1 |
| Sankalé, M | 1 |
| Coly, D | 1 |
2 reviews available for tinidazole and Abscess, Amebic, Hepatic
| Article | Year |
|---|---|
The treatment of intestinal protozoan infections.
Topics: Amebicides; Antimalarials; Antiprotozoal Agents; Balantidiasis; Chloroquine; Coccidiosis; Dientamoeb | 1982 |
[Amoebic liver abscess].
Topics: Antitrichomonal Agents; Drug Therapy, Combination; Humans; Liver Abscess, Amebic; Metronidazole; Tin | 1999 |
12 trials available for tinidazole and Abscess, Amebic, Hepatic
| Article | Year |
|---|---|
Comparative study of tinidazole versus metronidazole in treatment of amebic liver abscess: A randomized control trial.
Topics: Administration, Oral; Adult; Amebicides; Female; Follow-Up Studies; Humans; Injections, Intravenous; | 2018 |
Comparison of tinidazole with metronidazole in the treatment of hepatic amoebiasis: a controlled double blind study.
Topics: Administration, Oral; Adult; Clinical Trials as Topic; Double-Blind Method; Humans; Liver Abscess, A | 1984 |
Single-day drug treatment of amebic liver abscess.
Topics: Double-Blind Method; Female; Humans; Liver Abscess, Amebic; Male; Nitroimidazoles; Ornidazole; Tinid | 1983 |
Tinidazole for the treatment of amoebic liver abscess.
Topics: Clinical Trials as Topic; Entamoeba histolytica; Feces; Humans; Liver Abscess, Amebic; Metronidazole | 1975 |
Comparative study of tinidazole and metronidazole in amoebic liver abscess.
Topics: Adult; Clinical Trials as Topic; Humans; Liver Abscess, Amebic; Male; Metronidazole; Nitroimidazoles | 1977 |
Treatment of amoebic liver abscess with tinidazole and metronidazole.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Liver Abscess, Amebic; Liver Function Tests; Male; | 1978 |
Tinidazole and metronidazole in hepatic amoebiasis.
Topics: Adolescent; Adult; Age Factors; Child; Clinical Trials as Topic; Female; Humans; Liver Abscess, Ameb | 1978 |
How does tinidazole compare with metronidazole? A summary report of Indian trials in amoebiasis and giardiasis.
Topics: Adult; Amebiasis; Child; Clinical Trials as Topic; Dysentery, Amebic; Female; Giardiasis; Humans; In | 1978 |
Tinidazole and metronidazole in hepatic amoebiasis.
Topics: Adolescent; Adult; Child; Female; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; N | 1978 |
Tinidazole in the treatment of amoebic liver abscess.
Topics: Adult; Clinical Trials as Topic; Female; Humans; Liver Abscess, Amebic; Male; Nitroimidazoles; Tinid | 1976 |
Low dose tinidazole in the treatment of amoebic liver abscess.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Humans; Liver Abscess, Amebic; Male; Middle Aged; Nit | 1985 |
A comparative trial of metronidazole v. tinidazole in the treatment of amoebic liver abscess.
Topics: Adult; Clinical Trials as Topic; Humans; Liver Abscess, Amebic; Metronidazole; Nitroimidazoles; Rand | 1985 |
20 other studies available for tinidazole and Abscess, Amebic, Hepatic
| Article | Year |
|---|---|
Bisamidines of 2,6-diaminoanthraquinone as antiamebic agents.
Topics: Amebiasis; Amebicides; Amidines; Animals; Anthraquinones; Cricetinae; Dysentery, Amebic; Entamoeba h | 1978 |
Creep in nitroimidazole inhibitory concentration among the Entamoeba histolytica isolates causing amoebic liver abscess and screening of andrographolide as a repurposing drug.
Topics: Drug Repositioning; Entamoeba histolytica; Humans; Liver Abscess, Amebic; Metronidazole; Nitroimidaz | 2023 |
Relapse of intestinal and hepatic amebiasis after treatment.
Topics: Amebicides; Antidiarrheals; Colonoscopy; Drug Therapy, Combination; Dysentery, Amebic; Humans; Iodoq | 2011 |
Entamoeba histolytica infection in men who have sex with men.
Topics: Antiprotozoal Agents; Dysentery, Amebic; Entamoeba histolytica; Entamoebiasis; Homosexuality, Male; | 2012 |
Tinidazole (Tindamax) - a new anti-protozoal drug.
Topics: Administration, Oral; Adult; Animals; Antiprotozoal Agents; Child; Child, Preschool; Dose-Response R | 2004 |
Amebic abscess of the spleen complicated by metronidazole-induced neurotoxicity: case report.
Topics: Adult; Amebiasis; Ataxia; Central Nervous System Diseases; Humans; Liver Abscess, Amebic; Male; Metr | 1994 |
[Amebic liver abscess: review of 13 cases].
Topics: Adult; Age Factors; Amebicides; Chloroquine; Drug Therapy, Combination; Emetine; Female; Humans; Liv | 1995 |
Simultaneous amoebic liver abscess and hepatitis A infection.
Topics: Acute Disease; Adult; Amebicides; Antitrichomonal Agents; Female; Furans; Hepatitis A; Humans; Liver | 1998 |
Multiple liver abscesses: an unusual case which demonstrates the importance of ultrasonography in the detection of liver pathology.
Topics: Anti-Bacterial Agents; Antitrichomonal Agents; Humans; Liver Abscess, Amebic; Liver Function Tests; | 1998 |
[Hepatic amebiasis in the Kilimanjaro region. Serodiagnosis on micro-specimens of dried blood and attempts at treatment with tinidazole (fasigyn)].
Topics: Adult; Aged; Alkaline Phosphatase; Emetine; Female; Fluorescent Antibody Technique; Hand; Humans; Li | 1975 |
Tinidazole and metronidazole in the treatment of amoebic liver abscess.
Topics: Adult; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Nitroimidazoles; Tinidazole | 1977 |
Comparative evaluation of tinidazole and metronidazole in the treatment of amoebic liver abscess.
Topics: Adult; Female; Humans; Liver Abscess, Amebic; Male; Metronidazole; Middle Aged; Nitroimidazoles; Tin | 1977 |
Amoebic liver abscess and clinical experiences with tinidazole in Bangladesh.
Topics: Adolescent; Adult; Aged; Bangladesh; Female; Humans; Liver Abscess, Amebic; Male; Middle Aged; Nitro | 1978 |
Tinidazole in the treatment of trichomoniasis, giardiasis and amoebiasis. Report of a multicentre study.
Topics: Adult; Amebiasis; Child; Dysentery, Amebic; Giardiasis; Humans; Liver Abscess, Amebic; Nitroimidazol | 1978 |
A study of tinidazole in hepatic amoebiasis.
Topics: Adult; Female; Humans; Liver Abscess, Amebic; Male; Middle Aged; Nitroimidazoles; Tinidazole | 1978 |
Tinidazole in treatment of amoebic liver abscess in children.
Topics: Child; Child, Preschool; Humans; Infant; Liver Abscess, Amebic; Nitroimidazoles; Nutrition Disorders | 1977 |
[Short treatment of hepatic amebiasis by tinidazole. Apropos of 10 cases].
Topics: Adolescent; Adult; Amoeba; Animals; Antibodies, Protozoan; Female; Humans; Liver Abscess, Amebic; Ma | 1991 |
[Diagnostic and therapeutic criteria in amebic liver abscess].
Topics: Diagnosis, Differential; Echinococcosis, Hepatic; Humans; Liver Abscess, Amebic; Male; Middle Aged; | 1986 |
[Use of tinidazole in hepatic amebiasis in Dakar (apropos of 11 cases)].
Topics: Adult; Female; Humans; Liver Abscess, Amebic; Male; Middle Aged; Nitroimidazoles; Tinidazole | 1974 |
Preliminary results of a trial in amoebic liver abscess: diagnosis by latex agglutination test and dry-blood sample serology. Treatment with tinidazole (Fasigyn).
Topics: Adolescent; Adult; Aged; Female; Fluorescent Antibody Technique; Humans; Latex Fixation Tests; Liver | 1974 |