timolol has been researched along with Ocular Hypertension in 594 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 63 (10.61) | 18.7374 |
1990's | 142 (23.91) | 18.2507 |
2000's | 210 (35.35) | 29.6817 |
2010's | 138 (23.23) | 24.3611 |
2020's | 41 (6.90) | 2.80 |
Authors | Studies |
---|---|
Allen, J; Almstead, ZY; Courtney, LF; Crist, M; Crosson, CE; Gardyan, M; Gopinathan, S; Gu, KJ; Hamman, BD; Harrison, BA; Key, B; Kimball, SD; Liu, Q; Liu, Y; Mabon, R; McKnight, B; Patel, N; Rawlins, DB; Rice, DS; Voronkov, MV; Whitlock, NA; Wilson, AG; Yates, PW; Zhang, Y; Zhou, J | 1 |
Almirante, N; Bastia, E; Blangetti, M; Chegaev, K; Durante, M; Fruttero, R; Gasco, A; Guglielmo, S; Impagnatiello, F; Lazzarato, L; Masini, E; Rolando, B | 1 |
Chang, SN; Kuo, BI; Lin, JW; Nishida, T; Wu, JH | 1 |
Aihara, M; Iwata, A; Kawata, H; Lu, F; Odani-Kawabata, N | 1 |
Bacharach, J; Bejanian, M; Belalcázar, S; Chen, MY; Ferguson, G; Goodkin, ML; Guo, Q; Liu, J; Robinson, MR; Tatham, A; Thieme, H; Wirta, DL | 1 |
Çakmak, K; Erbil, H; Korkmaz, Ş; Mesci, C | 1 |
Asghari, A; Ozmaie, S; Rajaei, SM; Ziadi, A | 1 |
Ansari, E; Chappiti, S; Pavicic-Astalos, J; Pinto-Bonilla, JC; Riva, I; Sacchi, M; Saénz-Francés, F | 1 |
Barbosa, GCS; Lima, VL; Mota, RT; Susanna, BN; Susanna, CN; Susanna, FN; Susanna, R | 1 |
Fassari, C; Holló, G; Kirwan, J; Lopez-Lopez, F; Oddone, F; Zimina, M | 2 |
Brye, N; Camp, A; Do, JL; El-Nimri, NW; Ghahari, E; Moghimi, S; Penteado, RC; Proudfoot, J; Rubio, V; Salcedo, M; Weinreb, RN; Yang, D | 1 |
Karlova, EV; Zolotarev, AV | 1 |
Ahn, HS; Chang, DJ; Chang, J; Kang, HY; Lee, H; Lee, JW; Suh, JK | 1 |
Oddone, F | 1 |
Alekseev, IB; Alekseeva, LI; Volkova, AV | 1 |
Bleskina, MY; Kolotilina, NE; Lisitsyn, AB; Loskutov, IA; Poromov, AA | 1 |
Gou, J; He, H; Long, L; Ning, Y; Tang, X; Wang, Z; Xiong, J; Yin, T; Zhang, Y; Zhao, J | 1 |
Achiron, A; Goldberg, M; Hayat, H; Masarwa, D | 1 |
Athanasopoulos, GP; Boboridis, KG; Haidich, AB; Katsanos, A; Katz, LJ; Konstas, AG; Pagkalidou, E; Voudouragkaki, IC | 1 |
Adachi, M; Aihara, M; Asato, R; Hamada, N; Hara, T; Mizoue, S; Muramatsu, T; Naito, T; Ohkubo, S; Sakata, R; Yoshikawa, K | 1 |
Paul, C | 1 |
Fang, Y; Gan, D; Jiang, R; Ku, H; Sun, X | 1 |
Holló, G; Kóthy, P; Oddone, F; Tanga, L | 1 |
Belfort, R; Chen, MY; Della Paolera, M; Goodkin, ML; Kim, T; Lopes Silva, MJ; Paula, JS | 1 |
Huang, S; Xing, Y; Zhang, K; Zhu, L | 1 |
Ciganov, AZ; Dorofeev, DA; Kryzhanovskaya, AV | 1 |
Chen, E; Denis, P; Duch, S; Erb, C; Klyve, P; Puska, P; Skov, J | 1 |
Chono, E; Kashiwagi, K; Koesters, S; Yap, PS | 1 |
Bejanian, M; Coote, M; Goodkin, ML; Guo, Q; Kolko, M; Medeiros, FA; Robinson, MR; Walters, TR; Weinreb, RN; Zhang, J | 1 |
Freddo, TF; Furtado, N; Ho, DY; Steenbakkers, M | 1 |
Germanova, VN; Karlova, EV; Petrov, SY | 1 |
Fechtner, RD; Heah, T; Kim, T; Kopczynski, CC; Lewis, RA; McKee, H; Myers, JS; Sheng, H; Singh, IP; Usner, DW | 1 |
George, RJ; Jain, V; Nair, AG; Natarajan, S | 1 |
Holló, G; Hutnik, CML; Katsanos, A; Katz, LJ; Konstas, AG; Pfeiffer, N; Quaranta, L; Schmetterer, L; Teus, MA; Uusitalo, H | 1 |
Liao, Y; Nie, X; Wang, Y | 1 |
Barbeau, M; Beauchemin, C; Cui, AX; Harasymowycz, P; Jobin-Gervais, K; Lachaine, J; Mathurin, K; Royer, C | 1 |
Armengol, L; Banchs, I; Canut, MI; Casaroli-Marano, RP; González, JR; Kudsieh, B; Mattlin, H; Villa, O | 1 |
Kim, JM; Lee, JW; Maglambayan, J; Park, KH; Park, SW; Simonyi, S | 1 |
Dagi Glass, LR; Kim, HM; Tran, AQ; Yang, C | 1 |
Ansari, E; Ayan, F; King, AJ; Kinsella, M; Ng, E; Nita, A; Pavicic-Astalos, J | 1 |
Azuara-Blanco, A; Freiberg, J; Kolko, M; Rives, AS; Skov, AG; Virgili, G | 1 |
Aihara, M; Kishimoto, N; Kizaki, J; Saito, Y; Shibasaki, Y; Wada, Y | 1 |
Coroneo, M; Huang, J; Kalloniatis, M; Tong, J; Zangerl, B | 1 |
Adachi, M; Aihara, M; Fukuchi, T; Matsuo, H; Sasaki, N; Togano, T | 1 |
Balsak, S; Erdem, S; Fuat Alakus, M; Kaydu, A; Ozkurt, ZG | 1 |
Nuzzi, R; Rolle, T; Spinetta, R | 1 |
Holopainen, JM; Pisella, PJ; Rantamäki, AH; Robciuc, A; Ruokonen, SK; Wiedmer, SK; Witos, J | 1 |
Aljasim, LA; Bradfield, Y; Dixon, ER; Feldman, R; Gustafson, N; Landry, T; Salem, C; Venkataraman, S | 1 |
Kaufman, PL; Liebmann, JM; Martin, KR; Vittitow, JL; Weinreb, RN | 1 |
Boboridis, KG; Holló, G; Irkec, M; Katsanos, A; Konstas, AGP | 1 |
Heah, T; Katz, LJ; Kopczynski, CC; McLaurin, E; Novack, GD; Ramirez-Davis, N; Serle, JB; Usner, DW | 1 |
Kim, YY; Na, KH; Park, JH; Yoo, C | 1 |
Gouws, P; Oliphant, H | 1 |
Hashimoto, M; Hizaki, H; Kuwayama, Y; Otsuka, N; Suzuki, K | 1 |
Arciniegas-Perasso, CA; Clemente-Tomás, R; Duch-Samper, AM; García-Ibor, F; Hervás-Hernandis, JM; Ruiz-Del Río, N | 1 |
Bobic-Radovanovic, A; Bozic, M; Knezevic, M; Marjanovic, I; Stojkovic, M | 1 |
Baudouin, C; Belkacem, S; Derdour, A; Garout, R; Ghroud, N; Kherroubi, R; Lazreg, S; Merad, Z; Meziane, M; Nouri, MT; Ouhadj, O; Tiar, M | 1 |
Heah, T; Kahook, MY; Kim, T; Kopczynski, CC; Mah, FS; Novack, GD; Raizman, MB; Ramirez-Davis, N; Serle, JB; Usner, DW | 1 |
Bacharach, J; Braswell, P; Heah, T; Khouri, AS; Kopczynski, CC; Lewis, RA; Serle, JB; Usner, DW | 1 |
Hayashi, K; Manabe, SI; Sato, T; Yoshida, M | 1 |
Bourne, RRA; Kaarniranta, K; Lorenz, K; Ropo, A; Traverso, CE; Vuorinen, J | 1 |
Aptel, F; Astakhov, YS; Clarke, J; Coupier, L; Csutak, A; Jugaste, T; Lavín-Dapena, C; Moreno-Montañés, J; Nordmann, JP; Pfeiffer, N; Schmickler, S; Stalmans, I; Volksone, L; Żarnowski, T | 1 |
Isakov, IN; Kolbasko, AV; Makogon, SI; Onishchenko, AL | 1 |
Chung, IY; Han, YS; Kim, GN; Park, JM; Seo, SW; Yoo, JM | 1 |
Ebigwai, JK; Edu, EA; Itam, EH; Mofunanya, AJ | 1 |
Dimopoulos, AT; Empeslidis, T; Haidich, AB; Holló, G; Konstas, AG; Mikropoulos, DG; Ritch, R; Teus, MA | 1 |
Baser, EF; Gülhan, C; Öztürk, B; Seymenoğlu, G | 1 |
Bagaglia, SA; Fogagnolo, P; Frezzotti, P; Haka, G; Iester, M; Menicacci, C; Mittica, P; Motolese, E; Motolese, I; Rossetti, L | 1 |
Karaśkiewicz, J; Lubiński, W; Penkala, K | 1 |
Akçali, G; Bozkurt, KT; Güney, E; Sezgin Akçay, Bİ; Unlü, C | 1 |
Arunachalam, C | 1 |
Barros, Jde N; Faria, NV; Gomes, JÁ; Mello, PA; Montiani-Ferreira, F; Nogueira-Filho, PA; Russ, HH | 1 |
Campagna, O; Colica, C; Cruciani, F; De Vico, U; Gharbiya, M | 1 |
Bernardo, FP; Gomes, B; Marques, FP; Portes, AL; Safady, MV; Santhiago, MR; Turiel, PR | 1 |
He, M; Huang, W; Wang, W | 1 |
Chen, X; Dong, Y; Fang, A; Hu, Y; Ling, Z; Liu, D; Sun, W; Sun, X; Wang, Y; Xing, Y; Ye, J; Yin, Z; Zhang, M | 1 |
Bejanian, M; Gil Pina, R; Goldberg, I; Lanzagorta-Aresti, A; Liu, C; Schiffman, RM | 1 |
Antón López, A; Holló, G; Hommer, A; Ropo, A | 1 |
Ghahari, E; Pakravan, M; Rad, SS; Yaseri, M; Yazdani, S | 1 |
Ando, T; Hamada, R; Hamasaki, Y; Hataya, H; Honda, M; Ishikura, K; Kawaguchi, E; Miura, M; Morikawa, Y; Nagaoka, Y; Noda, E; Sakai, T | 1 |
Abegāo Pinto, L; Lequeu, I; Stalmans, I; Theuwis, K; Vandewalle, E | 1 |
Cong, X; Molloy, B | 1 |
Alezzandrini, A; Alfaro, R; Hubatsch, D | 1 |
Lorenz, K; Pfeiffer, N | 1 |
Bautista, D; Chew, PT; Khoo, AL; Lim, BP; Lin, L; Sng, CC; Teng, M; Wong, HT; Wu, TS; Yip, LW; Zhao, YJ | 1 |
Holló, G; Huttunen, T; Pfeiffer, N; Ropo, A; Tuominen, J; Vuorinen, J | 1 |
Özyol, E; Özyol, P | 1 |
Astakhov, Y; Boiko, E; Liinamaa, J; Lorenz, K; Pfeiffer, N; Ropo, A; Saarela, V; Traverso, CE; Uusitalo, H | 1 |
Agarwal, P; Agarwal, R; Ismail, NM; Kannan Kutty, M; Kapitonova, MY; Razali, N; Salmah Bakar, N; Smirnov, A | 1 |
García-López, A; Hartleben, C; Jiménez-Román, J; Paczka, JA | 1 |
Boehm, A; Centofanti, M; Fogagnolo, P; Goldblum, D; Karabatsas, CH; Rossetti, L; Sacchi, M; Topouzis, F; Vetrugno, M; Vorwerk, C | 1 |
Alagoz, G; Altun, G; Celik, E; Turkoglu, EB | 1 |
Abe, H; Araie, M; Inoue, T; Kuwayama, Y; Suganami, H; Tanihara, H; Yamamoto, T | 1 |
Agarwal, P; El-Assal, K; Khan, AA; Mustafa, MZ | 1 |
Fang, Y; Ling, Z; Sun, X | 1 |
Boccolucci, A; Cagini, C; Cerquaglia, A; Di Pasquale, G; Fiore, T; Lupidi, M | 1 |
Liu, KL; Lwin, NC; Ng, XW; Veluchamy, AB; Venkatraman, SS; Wong, TT | 1 |
Adachi, M; Aihara, M; Hamada, N; Honda, N; Koseki, N; Matsuo, H; Miyata, K; Otani, S; Unoki, K | 1 |
Akaishi, T; Kawazu, K; Miyawaki, N; Shimazaki, A; Tonouchi, A; Ueda, K | 1 |
Fuse, N; Iwase, A; Matsumoto, S; Mizoue, S; Nakano, T; Yoshikawa, K | 1 |
Hoy, SM | 1 |
Berardo, F; Centofanti, M; Ferrazza, M; Manni, G; Michelessi, M; Oddone, F; Roberti, G; Rossetti, L; Tanga, L | 1 |
Ha, SJ; Seo, du R | 1 |
Kanda, T; Mine, I; Sakurai, Y; Shibata, M; Taguchi, M; Takeuchi, M | 1 |
Liebmann, J; Scassellati Sforzolini, B; Vittitow, J; Weinreb, RN | 1 |
Sah, AK; Suresh, PK | 1 |
Holló, G; Konstas, AG | 1 |
Martin, KR; Medeiros, FA; Peace, J; Scassellati Sforzolini, B; Vittitow, JL; Weinreb, RN | 1 |
Baranak, C; Chabi, A; Herring, WJ; Lupinacci, R | 1 |
Akaishi, T; Fuwa, M; Kawazu, K; Kirihara, T; Mano, H; Shimazaki, A; Ueda, K; Yamashita, N | 1 |
Konstantinidis, A; Kozobolis, V; Labiris, G; Panos, GD | 1 |
Liu, JHK; Scassellati Sforzolini, B; Slight, JR; Vittitow, JL; Weinreb, RN | 1 |
Cong, X; Molloy, BL; Watson, C | 1 |
Li, J; Liu, D; Pan, H; Pan, W; Tan, G; Yang, X; Yu, S; Yuan, K | 1 |
Henao-Guerrero, N; Herring, IP; Matusow, RB; Pickett, JP; Werre, SR | 1 |
Boboridis, KG; Haidich, AB; Kapis, P; Katsanos, A; Konstas, AG; Marinopoulos, K; Mikropoulos, DG; Pagkalidou, E; Panayiotou, D; Quaranta, L; Voudouragkaki, IC | 1 |
Barnebey, HS; Robin, AL | 1 |
DeWitt, PE; Kahook, MY; Kroehl, ME; Seibold, LK | 1 |
Armour, MD; Dees, DD; Greller, A; Madsen, R; Paglia, D; Spahn, KJ; Wagner, LS | 1 |
Bell, K; Keicher, A; Lorenz, K; Pfeiffer, N; Renieri, G; Ruckes, C; Thieme, H; Wasielica-Poslednik, J | 1 |
Besada, E; Frauens, BJ; Shechtman, D | 1 |
Arzeno, G; Bergamini, MV; Dickerson, JE; Hua, SY; James, JE; Kaback, M; Landry, TA; Salem, C; Scoper, SV | 1 |
Batoosingh, AL; Cohen, JS; Gross, RL; Liu, CC; Safyan, E; Williams, RD | 1 |
Higuchi, S; Kawazu, K; Kitahara, T; Nakamura, J; Nakashima, M; Nishida, K; Sakanaka, K; Sasaki, H; Tomonari, M | 1 |
Hunter, A; Liu, W; Ma, J; Zhang, W | 1 |
Czechowicz-Janicka, K; Kałuzny, BJ; Kałuzny, J; Kecik, D; Sobecki, R; Stewart, JA; Stewart, WC | 1 |
Batiste, C; Fudemberg, SJ; Katz, LJ | 1 |
Berdeaux, G; Denis, P; Jeanbat, V; Lafuma, A; Laurendeau, C | 1 |
Kim, JH; Lee, NY; Park, CK; Park, HY | 1 |
Evans, RM; Mallick, S; Stewart, RH; Vold, SD; Walters, T | 1 |
Barbosa, WL; Grigera, DE; Hatanaka, M; Jordao, M; Susanna, R | 1 |
Berdeaux, G; De Natale, R; Lafuma, A | 1 |
Liu, JH; Medeiros, FA; Slight, JR; Weinreb, RN | 1 |
Balestrazzi, A; Frezzotti, P; Malandrini, A; Martone, G; Mittica, V; Motolese, E; Motolese, I; Motolese, PA; Pichierri, P; Tosi, GM; Traversi, C | 1 |
Chalkidou, S; Georgopoulos, G; Halkiadakis, I; Kostakou, A; Markomichelakis, NN; Papakonstantinou, D | 1 |
Curran, MP; Orman, JS | 1 |
Cai, JP; Cheng, JW; Li, Y; Wei, RL; Xi, GL | 1 |
Longo, A; Reibaldi, M; Uva, MG | 1 |
Buchholz, P; Feuerhake, C; Kimmich, F | 1 |
Delgado-Ortega, L; Díaz-Cerezo, S; Pinazo-Durán, MD; Soto-Alvarez, J; Vinuesa-Silva, I; Vinuesa-Silva, JM | 1 |
Konstas, AG; Kozobolis, VP; Lasaridis, AN; Mikropoulos, D; Nelson, LA; Pikilidou, MI; Sarafidis, PA; Stewart, WC; Tsironi, S | 1 |
Eysteinsson, T; Gottfredsdottir, MS; Hardarson, SH; Harris, A; Karlsson, RA; Stefánsson, E; Traustason, S | 1 |
Bean, GW; Grunden, JW; Hwang, LJ; Sultan, MB; Varma, R | 1 |
Galet, VA; Jia, G; Olander, KW; Smugar, SS; Stewart, WC | 1 |
Chartrand, JP; Hollander, DA; Nixon, DR; Piemontesi, RL; Simonyi, S; Yan, DB | 1 |
Croxtall, JD; Scott, LJ | 1 |
Agarwal, R; Agrawal, SS; Gupta, SK; Saxena, R; Srivastava, S | 1 |
Jamshidian-Tehrani, M; Mehdizadeh, M; Nowroozzadeh, MH | 1 |
Laxmana Rao, HB; Sekhar, GC | 1 |
Bellini, R; Bracchino, M; Bucarelli, M; Caravati, C; Celesia, L; Cerqueti, P; Clemente, A; Franchin, S; Pasinetti, GM; Rossi, GC; Tinelli, C | 1 |
Bozkurt, B; Holló, G; Irkec, M | 1 |
Bean, GW; Grunden, JW; Hwang, LJ; Varma, R | 1 |
Díaz, F; García-Campos, J; Moreno, M; Pérez de Vargas, I; Vidal, L; Villena, A | 1 |
Fuchsjäger-Mayrl, G; Garhöfer, G; Georgopoulos, M; Hommer, A; Pemp, B; Schmetterer, L; Vass, C; Weigert, G | 1 |
Batoosingh, AL; Gross, RL; Lewis, RA; Liu, CC; Sall, KN; Schiffman, RM | 1 |
de Moraes, CG; Facio, AC; Hatanaka, M; Reis, AS; Susanna, R; Suzuki, R; Vidal, KS | 1 |
Colen, TP; Lemij, HG; Reus, NJ; van der Schoot, J | 1 |
Mundorf, TK; Sonty, S; Stewart, JA; Stewart, WC | 1 |
Grunden, JW; Kwok, K; Miglior, S | 1 |
Grunden, JW; Higginbotham, EJ; Kim, EE; Kwok, KK; Olander, KW; Tressler, CS | 1 |
Camras, CB; Fan, S; Johnson, TV; Toris, CB; Zhan, G | 1 |
Baudouin, C; Bron, A; Denis, P; Nordmann, JP; Renard, JP; Rouland, JF; Sellem, E | 1 |
Brinkmann, CK; Katsimpris, JM; Lepidas, J; Livieratou, A; Petropoulos, IK; Theoulakis, PE | 1 |
Calvo-González, C; Fernández-Vidal, A; García-Feijoó, J; García-Sánchez, J; Martínez-de-la-Casa, JM; Méndez-Hernández, C; Sáenz-Francés, F | 1 |
Adamsons, IA; Getson, AJ; Hewitt, DJ; Ho, TW; Laurence, JK; Lines, CR; Shedden, A | 1 |
Huang, P; Li, H; Liu, J; Tang, Y; Wei, R; Xu, Y; Zhang, C; Zhang, SS | 1 |
Hendrikse, F; Peeters, A; Prins, MH; Schouten, JS; Severens, JL; Webers, CA | 1 |
Guzy, C; Heckmann, B; Miller, PJ; Schwenn, O | 1 |
García-Pérez, JL; González-Gordaliza, C; Muñoz-Negrete, FJ; Puerto-Hernández, B; Rebolleda Fernández, G | 1 |
Bastien, NR; Behki, R; Boucher, S; Crichton, AC; Harasymowycz, P; Hutnik, CM; Ibrahim, F; Liao, C; Rifkind, AW; Sampalis, JS; Solomon, L | 1 |
Li, J; Lin, X; Wu, K; Yang, Y; Yu, M; Yuan, H | 1 |
Crowston, JG; Goldberg, I; Jasek, MC; Stewart, JA; Stewart, WC | 1 |
Bernstein, P; Caprioli, J; Schiffman, RM; Spaeth, GL | 1 |
Biuk, D; Bojic, L; Dobutovic, D; Kovacic, Z; Mandic, Z; Maricic-Došen, V; Novak-Lauš, K; Pavan, J; Pelcic, G; Popovic-Suic, S | 1 |
Sihota, R | 1 |
Hendrikse, F; Peeters, A; Prins, MH; Schouten, JS; Webers, CA | 1 |
Dastiridou, AI; Fanariotis, M; Katsanos, A; Kotoula, M; Tsironi, EE | 1 |
Georgakopoulos, CD; Giannopoulos, K; Makri, OE; Pharmakakis, N; Stasinos, S | 1 |
Abdlseaed, AA; Abeysinghe, SS; Kelly, S; Montgomery, DM; Rahman, MQ; Roskell, NS; Shannon, PR | 1 |
David, R; Kurtz, S; Newman, H | 1 |
Baudouin, C; Brignole-Baudouin, F; Liang, H; Nakib, Z; Riancho, L | 1 |
Baudouin, C; Brignole-Baudouin, F; Liang, H; Pauly, A; Riancho, L | 1 |
García-Pérez, JL; González-Gordaliza, C; Muñoz-Negrete, FJ; Puerto-Hernández, B; Rebolleda, G | 1 |
Pfeiffer, N | 2 |
Dombi, TM; Huang, K; Jessen, B; Kwok, KK; Tressler, CS; Wirostko, BM; Wiseman, RL | 1 |
Liu, JH; Realini, T; Weinreb, RN | 1 |
Bae, K; Iwamoto, Y; Kitazawa, Y; Kotake, S; Sasaki, N; Smith, P | 1 |
Amato, R; Avitabile, T; Gagliano, C; Longo, A; Ortisi, E; Pulvirenti, L; Reibaldi, M; Scollo, D | 1 |
Pachimkul, P; Thoophom, P; Yuttitham, K | 1 |
Araie, M; Kitazawa, Y | 1 |
Liehneova, I; Negrete, FJ; Scherzer, ML; Schnober, D | 1 |
Babić, N; Camara, C; Cieślińska, I; Ferkova, S; Holló, G; Januleviciene, I; Kaluzny, BJ; Kóthy, P; Kozobolis, V; Kristoffersen, MS; Krzyzanowska-Berkowska, P; Mikropoulos, DG; Misiuk-Hojlo, M; Nelson, LA; Quaranta, L; Russo, A; Stewart, JA; Stewart, WC; Teus, MA; Thelen, U | 1 |
Novack, GD | 1 |
Barisić, F; Biuk, D; Bojić, L; Clementi, D; Dobutović, D; Dogan, KK; Dosen, VM; Ekert, M; Geser, MZ; Iveković, R; Jurić-Miletić, A; Kovacević, S; Kovacić, Z; Krolo, I; Mandić, Z; Novak-Laus, K; Pavan, J; Pelcić, G; Popović-Suić, S; Susić, N; Tomić, M | 1 |
Ge, J; Li, XX; Li, YM; Sheng, YH; Sun, NX; Sun, XH; Yao, K; Zhao, JL; Zhong, Z | 1 |
Escalada, A; García Sánchez, J; García-Feijoó, J; Martínez-de-la-Casa, JM; Sáenz-Francés, F; Sánchez-Pulgarín, M | 1 |
Higa, R; Inoue, K; Okayama, R; Sawada, H; Tomita, G; Wakakura, M | 1 |
Grover, DS; Smith, O | 1 |
Kobayashi, H | 2 |
Baranak, C; Chabi, A; Ho, TW; Lines, C; Lupinacci, R; Noble, L; Pigeon, J; Tsai, JC; Varma, R | 1 |
Fan, S; Gangahar, C; Gulati, V; Maslonka, MA; Toris, CB; Zhao, M | 1 |
Cottingham, AJ; Hollander, DA; Katz, LJ; Rauchman, SH; Schiffman, RM; Simmons, ST; Williams, JM | 1 |
De Bacquer, D; Kestelyn, PA; Kestelyn, PG; Stevens, AM | 1 |
Kashiwagi, K | 1 |
Chen, DF; Chen, H; Cho, KS; Guo, W; Luo, G; Pang, IH; Wang, WH; Yang, Q; Yu, D | 1 |
Garhöfer, G; Hommer, A; Popa-Cherecheanu, A; Qiao, C; Resch, H; Schmetterer, L; Sperl, P | 1 |
Dot, C; El Chehab, H; Giraud, JM; Le Corre, A; Ract-Madoux, G; Swalduz, B | 1 |
Inoue, K; Shiokawa, M; Soeda, S; Sugahara, M; Tomita, G; Wakakura, M | 1 |
Beckers, HJ; Brink, HM; Busch, MJ; Colen, TP; Schouten, JS; Webers, CA | 1 |
Biagioli, E; Floriani, I; Katsanos, A; Poli, D; Quaranta, L; Riva, I; Rulli, E | 1 |
Araie, M; Kuwayama, Y; Sugiyama, K; Tanihara, H; Yamazaki, Y | 1 |
Goldberg, I | 1 |
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Diestelhorst, M; Nordmann, JP; Toris, CB | 1 |
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Goñi, FJ | 1 |
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Cohen, JS; Netland, PA; Nussbaum, LL; Stewart, WC; Weiss, HS | 1 |
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Azuma, I; Kitazawa, Y; Masuda, K; Yamamoto, T | 1 |
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Hosokawa, T; Inoue, T; Koike, H; Mori, Y; Sasaki, Y; Yanagisawa, H; Yokoyoma, T | 1 |
Fu, P; Guo, W; Li, M; Li, S; Meng, F; Peng, D; Shao, H; Sheng, Y; Sun, X; Xu, C; Yu, K; Zhu, Z | 1 |
Davis, AA; Fellman, RL; Ratliff, M; Silver, LH; Sullivan, EK; Turner, FD; Weiner, AL; Whitson, JT | 1 |
Dobbins, T; Halper, LK; Hartenbaum, D; Johnson-Pratt, L | 1 |
Easthope, SE; Perry, CM | 1 |
Konstas, AG; Lallos, NA; Leech, JN; Nakos, E; Stewart, WC; Tersis, I | 1 |
Whitson, JT | 1 |
Benozzi, J; Campanelli, JL; Nahum, LP; Rosenstein, RE | 1 |
Dubiner, H; Feldman, R; Higginbotham, EJ; Stiles, M | 1 |
Robin, AL | 1 |
Halper, LK; Hartenbaum, D; Johnson-Pratt, L; Polis, A; Stewart, WC | 1 |
Béchetoille, A; Brunner-Ferber, FL; Buntinx, A; Clineschmidt, C; Gerling, J; Grehn, F; Gunning, F; Holder, D; Lippa, EA; Pfeiffer, N | 1 |
Camras, CB; Deasy, D; Framm, L; Lippa, EA; Lustgarten, J; Payne, JE; Podos, SM; Serle, JB | 1 |
Batterbury, M; Harding, SP; Wong, D | 1 |
Batterbury, M; Wishart, PK | 1 |
Chen, YJ; Chiou, GC | 1 |
Bricker, SR; McGalliard, JN; Mercer, NP; Mostafa, SM; Smith, GT; Trimble, RB | 1 |
Li, S; Liu, Y; Yang, W | 1 |
Lee, SH; Lee, SY; Parrow, KA; Shin, DH; Yaldo, MK | 1 |
Cai, FY; Zhu, MD | 1 |
Béchetoille, A; Gerling, J; Grehn, F; Greve, E; Gunning, F; Jaquet-Müller, F; Lippa, EA; Pfeiffer, N | 1 |
Choplin, N; Kelley, E; Lue, J; Mundorf, T; Rose, A; Silverstone, D; Stoecker, J; Zimmerman, T | 1 |
Marquardt, R; Schubert, T | 1 |
Gaasterland, DE; Javitt, JC; Street, DA | 1 |
Douglas, GR; Drance, SM; Schulzer, M; Wijsman, KJ | 1 |
Douglas, GR; Drance, SM; Schulzer, M | 1 |
Grunwald, JE | 2 |
Aasved, H; Bergaust, B; Bulie, T; Høvding, G; Løfors, KT; Viksmoen, L | 1 |
Longstaff, S; West, J | 1 |
Blackmore, H; Bulpitt, CJ; Crick, RP; Newson, RB; Shipley, MJ | 1 |
Geyer, O; Lazar, M; Rothkoff, L | 1 |
Gordon, MO; Kass, MA; Nesher, R; Trick, GL | 1 |
Buncic, JR; Trope, GE; Tytla, ME | 1 |
Sponsel, WE | 1 |
Gans, LA; Kass, MA; Nesher, R | 1 |
Brettschneider, I; Brozek, B; Krejcí, L | 1 |
Remler, BF; Tomsak, RL | 1 |
Kass, MA | 1 |
Brooks, AM; Clark, JB; Gillies, WE; Harper, CA; Mantzioros, N | 1 |
Hong, YJ; McCarty, B; Parrow, KA; Shi, DX; Shin, DH | 1 |
De Heer, LJ; De Keizer, RJ; Maas, S; Ros, FE | 1 |
Ji, XC; Zhao, F; Zheng, YZ | 1 |
Almog, Y; Friedland, BR; Kelley, EP; Lazar, M; LeBlanc, RP; Lee, PF; Mann, C; Novack, GD; Orr, A; Rakofsky, SI | 1 |
Diestelhorst, M; Krieglstein, GK | 1 |
Edelstein, DJ; Epstein, DL; Hertzmark, E; Krug, JH; Remis, LL | 1 |
Dandona, L; Morrison, JC; Quigley, HA; Robin, AL | 1 |
Chauhan, BC; Douglas, GR; Drance, SM | 2 |
Heijl, A | 1 |
Schwartz, B | 1 |
Becker, B; Gordon, MO; Hart, WM; Hoff, MR; Kass, MA; Kolker, AE; Parkinson, JM | 1 |
Batoosingh, AL; David, R; Elman, J; Masi, R; Novack, GD; Ober, M; Sears, ML | 1 |
Caprioli, J; Elman, J; Mead, A; Petillo, J; Rosanelli, EG; Sears, M; Shields, R | 1 |
Demailly, P; Savelsbergh-Fillette, MP | 1 |
Blasi, NA; Carrascosa-Cerquero, A; Fernandez-Vozmediano, JM; Romero-Cabrera, MA | 1 |
Batoosingh, AL; Freyler, H; Menapace, R; Mordaunt, J; Novack, GD; Skorpik, C | 1 |
Gibbens, MV | 2 |
Reddy, PS | 1 |
Krieglstein, GK; Mueller, B; Scoville, B; White, BG | 1 |
Batoosingh, AL; David, R; Duzman, E; Freeman, MI; Lee, PF; Novack, GD | 1 |
Allen, RC; Batoosingh, AL; Boozman, FW; Carriker, R; Foerster, R; Novack, GD | 1 |
Cinotti, AA; Constad, WH; Fiore, P; Samson, C | 1 |
Jacobs, NJ; Mills, KB; Vogel, R | 1 |
LeBlanc, R; Novack, G; Saheb, N; Seamone, C | 1 |
Aasved, H; Høvding, G | 1 |
Lustgarten, JS | 1 |
Stilma, JS | 1 |
Fellman, RL; Starita, RJ | 1 |
Duzman, E; Geyer, O; Lazar, M; Lue, JC; Novack, GD | 1 |
Beckman, H; Channell, MM; Migliori, ME | 1 |
Péchereau, A | 1 |
Flury, H; Martenet, AC; Tournoux, A | 1 |
Gherezghiher, T; Koss, MC; March, WF; Nordquist, RE | 1 |
Bouchey, R; Cinotti, A; Cinotti, D; Esters, J; Galin, M; Grant, W; Jacobs, I; Lee, J; Shin, D; Silverstone, D | 1 |
Berson, FG; Cohen, HB; Duzman, E; Foerster, RJ; Lass, JH; Novack, GD | 1 |
Biedner, BZ; David, R; Duzman, E; Lue, JC; Novack, GD; Ober, M; Robins, DS; Scharrer, A | 1 |
Krip, G; LeBlanc, RP; Saheb, NE | 1 |
60 review(s) available for timolol and Ocular Hypertension
Article | Year |
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Intraocular pressure-lowering efficacy and ocular safety of Rho-kinase inhibitor in glaucoma: a meta-analysis and systematic review of prospective randomized trials.
Topics: Antihypertensive Agents; Double-Blind Method; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Randomized Controlled Trials as Topic; rho-Associated Kinases; Timolol; Treatment Outcome | 2022 |
Comparison of Netarsudil/Latanoprost Therapy with Latanoprost Monotherapy for Lowering Intraocular Pressure: A Systematic Review and Meta-analysis.
Topics: Antihypertensive Agents; Benzoates; beta-Alanine; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; rho-Associated Kinases; Timolol; Treatment Outcome | 2022 |
[Xalacom: possibilities and advantages of the drug in the treatment of patients with glaucoma].
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quality of Life; Timolol; Treatment Outcome | 2022 |
[ROCK (RHO-KINASE INHIBITORS) FOR THE TREATMENT OF OPEN-ANGLE GLAUCOMA AND OCULAR HYPERTENSION].
Topics: Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Timolol; Treatment Outcome; United States | 2023 |
The efficacy of the fixed combination of latanoprost and timolol versus other fixed combinations for primary open-angle glaucoma and ocular hypertension: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Bimatoprost; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2020 |
Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2021 |
Short-term efficacy of latanoprostene bunod for the treatment of open-angle glaucoma and ocular hypertension: a systematic literature review and a network meta-analysis.
Topics: Amides; Antihypertensive Agents; Bayes Theorem; Betaxolol; Bimatoprost; Brimonidine Tartrate; Carteolol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Network Meta-Analysis; Ocular Hypertension; Prostaglandins A; Prostaglandins F, Synthetic; Timolol; Travoprost | 2022 |
Comparative efficacy and safety of preserved versus preservative-free beta-blockers in patients with glaucoma or ocular hypertension: a systematic review.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol | 2022 |
Preservative-Free Prostaglandin Analogs and Prostaglandin/Timolol Fixed Combinations in the Treatment of Glaucoma: Efficacy, Safety and Potential Advantages.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzalkonium Compounds; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins; Prostaglandins, Synthetic; Retrospective Studies; Timolol | 2018 |
Electrophysiological tests in evaluation of glaucoma and ocular hypertension treatment--up to date knowledge. A review.
Topics: Acetazolamide; Dose-Response Relationship, Drug; Electroretinography; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Trabeculectomy; Treatment Outcome | 2013 |
Efficacy and tolerability of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Drug Tolerance; Female; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2013 |
Efficacy and safety of tafluprost 0.0015% and timolol maleate 0.5% fixed combination in patients with ocular hypertension or open-angle glaucoma.
Topics: Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug-Related Side Effects and Adverse Reactions; Glaucoma; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Prostaglandins F; Timolol | 2014 |
Comparative efficacy and tolerability of topical prostaglandin analogues for primary open-angle glaucoma and ocular hypertension.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost | 2014 |
Fixed-dose combination of tafluprost and timolol in the treatment of open-angle glaucoma and ocular hypertension: comparison with other fixed-combination products.
Topics: Adrenergic beta-Antagonists; Amides; Cloprostenol; Double-Blind Method; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F; Randomized Controlled Trials as Topic; Timolol | 2014 |
Fixed-combination treatments for intraocular hypertension in Chinese patients - focus on bimatoprost-timolol.
Topics: Adrenergic beta-Antagonists; Asian People; Bimatoprost; China; Drug Combinations; Glaucoma; Humans; Ocular Hypertension; Timolol | 2015 |
Tafluprost/Timolol: A Review in Open-Angle Glaucoma or Ocular Hypertension.
Topics: Adrenergic beta-Antagonists; Drug Combinations; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F; Timolol | 2015 |
Medical management of glaucoma: focus on ophthalmologic drug delivery systems of timolol maleate.
Topics: Antihypertensive Agents; Biological Availability; Disease Management; Drug Delivery Systems; Emulsions; Epithelium, Corneal; Glaucoma; Humans; Hydrogels; Intraocular Pressure; Microspheres; Nanoparticles; Ocular Hypertension; Ophthalmic Solutions; Permeability; Polymers; Timolol | 2017 |
Preservative-free tafluprost/timolol fixed combination: a new opportunity in the treatment of glaucoma.
Topics: Antihypertensive Agents; Disease Management; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F; Quality of Life; Timolol | 2016 |
Efficacy, safety, and current applications of brimonidine.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Timolol; Treatment Outcome | 2008 |
Bimatoprost/timolol: a review of its use in glaucoma and ocular hypertension.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Cost-Benefit Analysis; Drug Combinations; Glaucoma; Humans; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2009 |
Efficacy and tolerability of latanoprost compared to dorzolamide combined with timolol in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized, controlled trials.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2009 |
[Development of conjunctival hyperemia with the use of a fixed combination of latanoprost/timolol: systematic review and meta-analysis of clinical trials].
Topics: Aged; Brimonidine Tartrate; Clinical Trials as Topic; Cloprostenol; Conjunctival Diseases; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Glaucoma; Humans; Hyperemia; Latanoprost; Middle Aged; Ocular Hypertension; Odds Ratio; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Timolol; Travoprost | 2009 |
Assessing the efficacy of latanoprost vs timolol using an alternate efficacy parameter: the intervisit intraocular pressure range.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Risk Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2009 |
Brinzolamide/timolol fixed combination: a new ocular suspension for the treatment of open-angle glaucoma and ocular hypertension.
Topics: Administration, Topical; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Suspensions; Thiazines; Timolol | 2009 |
An Indian perspective on primary angle closure and glaucoma.
Topics: Acute Disease; Anterior Chamber; Antihypertensive Agents; Chronic Disease; Cornea; Disease Progression; Drug Administration Schedule; Glaucoma, Angle-Closure; Humans; Incidence; India; Iris; Latanoprost; Ocular Hypertension; Ophthalmologic Surgical Procedures; Prevalence; Prostaglandins F, Synthetic; Timolol | 2011 |
Lack of evidence for a link between latanoprost use and malignant melanoma: an analysis of safety databases and a review of the literature.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Child; Child, Preschool; Databases, Factual; Drug Combinations; Evidence-Based Medicine; Eye Neoplasms; Female; Humans; Latanoprost; Male; Melanoma; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Skin Neoplasms; Timolol; Young Adult | 2011 |
Recent clinical pearls from clinical trials in glaucoma.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Filtering Surgery; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Low Tension Glaucoma; Ocular Hypertension; Quinoxalines; Timolol; Tonometry, Ocular | 2012 |
Prostaglandin analogs and timolol-fixed versus unfixed combinations or monotherapy for open-angle glaucoma: a systematic review and meta-analysis.
Topics: Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Ocular Hypertension; Prostaglandins; Timolol | 2013 |
The effect of latanoprost on circadian intraocular pressure.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2002 |
Bimatoprost and travoprost: a review of recent studies of two new glaucoma drugs.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost | 2002 |
Latanoprost versus combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
Combined therapy of pilocarpine or latanoprost with timolol versus latanoprost monotherapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Muscarinic Agonists; Ocular Hypertension; Pilocarpine; Prostaglandins F, Synthetic; Timolol | 2002 |
[Comparison of latanoprost monotherapy with timolol-dorzolamide combination in patients with open-angle glaucoma or ocular hypertension].
Topics: Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
Four years later: a clinical update on latanoprost.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Eye; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
Latanoprost : an update of its use in glaucoma and ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Combinations; Eye Diseases; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2003 |
Pooled-data analysis of three randomized, double-masked, six-month studies comparing intraocular pressure-reducing effects of latanoprost and timolol in patients with ocular hypertension.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Retrospective Studies; Timolol; Treatment Outcome | 2003 |
An evaluation of the fixed-combination of latanoprost and timolol for use in open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol | 2004 |
[Timolol topical ophthalmic combination].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
[Latanoprost topical ophthalmic combinations].
Topics: Acetazolamide; Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Dinoprost; Drug Combinations; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2004 |
Intraocular pressure-lowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Prescriptions; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prostaglandins, Synthetic; Randomized Controlled Trials as Topic; Timolol | 2005 |
[Does the ocular hypertension need treatment].
Topics: Antihypertensive Agents; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Risk Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2006 |
Topical brimonidine 0.2%/timolol 0.5% ophthalmic solution: in glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Timolol; Treatment Outcome | 2006 |
Travoprost compared with other prostaglandin analogues or timolol in patients with open-angle glaucoma or ocular hypertension: meta-analysis of randomized controlled trials.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Dinoprost; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost | 2006 |
Topical dorzolamide 2%/timolol 0.5% ophthalmic solution: a review of its use in the treatment of glaucoma and ocular hypertension.
Topics: Drug Combinations; Glaucoma; Humans; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Vision, Ocular | 2006 |
Travoprost 0.004%/timolol 0.5% fixed combination.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Timolol; Travoprost | 2007 |
Efficacy and safety of bimatoprost/timolol fixed combination in the treatment of glaucoma or ocular hypertension.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Blood Pressure; Cloprostenol; Drug Combinations; Glaucoma; Humans; Lipids; Ocular Hypertension; Timolol; Treatment Outcome | 2008 |
Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2008 |
Travoprost/timolol fixed combination.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Patient Compliance; Timolol; Travoprost | 2008 |
Topical ophthalmic beta-adrenergic blockade for the treatment of glaucoma and ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Humans; Levobunolol; Metipranolol; Ocular Hypertension; Timolol | 1994 |
Will latanoprost be the 'wonder' drug of the '90s for the treatment of glaucoma?
Topics: Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 1996 |
Timolol hemihydrate: a new formulation of timolol for the treatment of glaucoma.
Topics: Adrenergic beta-Antagonists; Animals; Chemistry, Pharmaceutical; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Timolol | 1996 |
Clinical dose-regimen studies with latanoprost, a new ocular hypotensive PGF2 alpha analogue.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 1997 |
Phase III latanoprost studies in Scandinavia, the United Kingdom and the United States.
Topics: Adrenergic beta-Antagonists; Clinical Trials, Phase III as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Scandinavian and Nordic Countries; Timolol; United Kingdom; United States | 1997 |
Brimonidine: a new alpha2-adrenoreceptor agonist for glaucoma treatment.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Betaxolol; Brimonidine Tartrate; Clinical Trials as Topic; Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Timolol; Trabeculectomy | 1997 |
Anesthesia and preoperative and postoperative medications.
Topics: Acetazolamide; Adrenergic beta-Antagonists; Anesthesia, Local; Anesthetics, Local; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Carbonic Anhydrase Inhibitors; Cataract Extraction; Humans; Hyaluronic Acid; Ocular Hypertension; Therapeutic Irrigation; Timolol | 1996 |
Atopic dermatitis: a case report and current clinical review of systemic and ocular manifestations.
Topics: Adrenergic beta-Antagonists; Cataract; Conjunctivitis, Allergic; Corneal Edema; Dermatitis, Atopic; Diagnosis, Differential; Female; Humans; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prednisolone; Prognosis; Timolol; Visual Acuity | 2001 |
Meta-analysis of randomised controlled trials comparing latanoprost with timolol in the treatment of patients with open angle glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Ocular Hypertension; Pigmentation Disorders; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Risk Factors; Single-Blind Method; Timolol; Treatment Outcome | 2001 |
Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension.
Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctival Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2002 |
Travoprost--a new prostaglandin analogue for the treatment of glaucoma.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Racial Groups; Receptors, Prostaglandin; Timolol; Travoprost | 2002 |
Development of D-timolol for the treatment of glaucoma and ocular hypertension.
Topics: Animals; Drug Evaluation; Glaucoma; Humans; Ocular Hypertension; Timolol | 1990 |
376 trial(s) available for timolol and Ocular Hypertension
Article | Year |
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Twelve-month efficacy and safety of omidenepag isopropyl, a selective EP2 agonist, in open-angle glaucoma and ocular hypertension: the RENGE study.
Topics: Antihypertensive Agents; Double-Blind Method; Glaucoma, Open-Angle; Glycine; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pyrazoles; Pyridines; Timolol; Treatment Outcome | 2021 |
Phase 3, Randomized, 20-Month Study of the Efficacy and Safety of Bimatoprost Implant in Patients with Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 2).
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Dose-Response Relationship, Drug; Double-Blind Method; Drug Implants; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Young Adult | 2021 |
Comparing the effects and safety of dorzolamide hydrochloride + timolol maleate versus brimonidine after neodymium-doped yttrium aluminium garnet laser capsulotomy posterior capsule opacification.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Capsule Opacification; Glaucoma; Humans; Intraocular Pressure; Lasers, Solid-State; Neodymium; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Yttrium | 2022 |
Effect of Topically Applied 0.5% Apraclonidine Versus 0.5% Timolol Maleate on Intraocular Pressure of Healthy Horses.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Double-Blind Method; Female; Horse Diseases; Horses; Intraocular Pressure; Lubricant Eye Drops; Ocular Hypertension; Timolol | 2022 |
Intraocular Peak Pressure in Patients Under Treatment With Fixed Combination of Bimatoprost/Timolol/Brimonidine Once Daily Versus Twice Daily.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Water | 2022 |
Comparison of the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density: A Randomized Clinical Trial.
Topics: Glaucoma, Open-Angle; Humans; Intraocular Pressure; Macula Lutea; Ocular Hypertension; Prostaglandins F, Synthetic; Retinal Vessels; Timolol; Tomography, Optical Coherence | 2022 |
Changing from preserved, to preservative-free cyclosporine 0.1% enhanced triple glaucoma therapy: impact on ocular surface disease-a randomized controlled trial.
Topics: Antihypertensive Agents; Cyclosporins; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Matrix Metalloproteinase 9; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Timolol; Treatment Outcome | 2023 |
Efficacy And Safety Of Travoprost Versus Timolol To Treat Early-Onset Ocular Hypertension Secondary To Vitrectomy: A Randomized Trial.
Topics: Female; Humans; Inflammation; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Risk Factors; Single-Blind Method; Timolol; Travoprost; Vitrectomy | 2019 |
Fixed-combination Bimatoprost/Brimonidine/Timolol in Glaucoma: A Randomized, Masked, Controlled, Phase III Study Conducted in Brazil
Topics: Aged; Antihypertensive Agents; Bimatoprost; Brazil; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 2020 |
Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1).
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Double-Blind Method; Drug Implants; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Tonometry, Ocular; Vitreous Body; Young Adult | 2020 |
Validation of a More Reliable Method of Eye Drop Self-Administration.
Topics: Administration, Ophthalmic; Adult; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Reproducibility of Results; Self Administration; Timolol; Tonometry, Ocular; Young Adult | 2020 |
[Preservative-free fixed combination in the treatment of open-angle glaucoma and ocular hypertension: the VISIONARY Study (EUPAS22204)].
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Russia; Timolol; Treatment Outcome | 2020 |
Pooled Efficacy and Safety Profile of Netarsudil Ophthalmic Solution 0.02% in Patients With Open-angle Glaucoma or Ocular Hypertension.
Topics: Administration, Ophthalmic; Adult; Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Timolol; Tonometry, Ocular; Treatment Outcome | 2020 |
MLIP genotype as a predictor of pharmacological response in primary open-angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alleles; Biomarkers; Co-Repressor Proteins; Cross-Over Studies; DNA Copy Number Variations; Female; Genome-Wide Association Study; Genotype; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol | 2021 |
Comparison of the 24-h efficacy and safety of fixed combination carteolol/latanoprost and timolol/latanoprost in patients with primary open-angle glaucoma and ocular hypertension: a prospective crossover study.
Topics: Antihypertensive Agents; Carteolol; Cross-Over Studies; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2021 |
Clinical Trial: Diurnal IOP Fluctuations in Glaucoma Using Latanoprost and Timolol with Self-Tonometry.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Manometry; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2021 |
Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin-treated glaucoma patients.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Follow-Up Studies; Glaucoma, Open-Angle; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Brimonidine-timolol versus brinzolamide-timolol for treatment of elevated intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2018 |
A 3-month safety and efficacy study of travoprost 0.004% ophthalmic solution compared with timolol in pediatric patients with glaucoma or ocular hypertension.
Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol; Tonometry, Ocular; Travoprost | 2017 |
Latanoprostene Bunod 0.024% in Subjects With Open-angle Glaucoma or Ocular Hypertension: Pooled Phase 3 Study Findings.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Visual Acuity; Young Adult | 2018 |
Two Phase 3 Clinical Trials Comparing the Safety and Efficacy of Netarsudil to Timolol in Patients With Elevated Intraocular Pressure: Rho Kinase Elevated IOP Treatment Trial 1 and 2 (ROCKET-1 and ROCKET-2).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzoates; beta-Alanine; Child; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2018 |
Multicenter, Randomized, Controlled Study Comparing Tafluprost/Timolol Fixed Combination with Latanoprost/Timolol Fixed Combination in Primary Open-Angle Glaucoma and Ocular Hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Japan; Latanoprost; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Young Adult | 2018 |
Efficacy and safety of preservative-free timolol 0.1% gel in open-angle glaucoma and ocular hypertension in treatment-naïve patients and patients intolerant to other hypotensive medications.
Topics: Adult; Aged; Aged, 80 and over; Algeria; Antihypertensive Agents; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2018 |
Long-term Safety and Ocular Hypotensive Efficacy Evaluation of Netarsudil Ophthalmic Solution: Rho Kinase Elevated IOP Treatment Trial (ROCKET-2).
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Timolol; Treatment Outcome | 2019 |
Once-Daily Netarsudil Versus Twice-Daily Timolol in Patients With Elevated Intraocular Pressure: The Randomized Phase 3 ROCKET-4 Study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzoates; beta-Alanine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Tonometry, Ocular; Treatment Outcome | 2019 |
Effect of Topical Hypotensive Medications for Preventing Intraocular Pressure Increase after Cataract Surgery in Eyes with Glaucoma.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cataract; Cataract Extraction; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2019 |
Changes in ocular signs and symptoms in patients switching from bimatoprost-timolol to tafluprost-timolol eye drops: an open-label phase IV study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intention to Treat Analysis; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Quality of Life; Timolol | 2019 |
Noninferiority of Preservative-free Versus BAK-preserved Latanoprost-timolol Fixed Combination Eye Drops in Patients With Open-angle Glaucoma or Ocular Hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzalkonium Compounds; Drug Combinations; Equivalence Trials as Topic; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol; Tonometry, Ocular; Treatment Outcome | 2019 |
24-hour efficacy of the bimatoprost-timolol fixed combination versus latanoprost as first choice therapy in subjects with high-pressure exfoliation syndrome and glaucoma.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Field Tests; Visual Fields | 2013 |
Comparison of dorzolamide/timolol versus brimonidine/timolol fixed combination therapy in the management of steroid-induced ocular hypertension.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Diabetic Retinopathy; Drug Combinations; Female; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Triamcinolone Acetonide | 2015 |
In vivo confocal microscopy of conjunctiva in preservative-free timolol 0.1% gel formulation therapy for glaucoma.
Topics: Adrenergic beta-Antagonists; Benzalkonium Compounds; Cell Count; Conjunctiva; Female; Gels; Glaucoma, Open-Angle; Goblet Cells; Humans; Intraocular Pressure; Male; Microscopy, Confocal; Middle Aged; Ocular Hypertension; Pharmaceutical Preparations; Preservatives, Pharmaceutical; Tears; Timolol; Tonometry, Ocular | 2014 |
The safety and efficacy of brinzolamide 1%/timolol 0.5% fixed combination versus dorzolamide 2%/timolol 0.5% in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Preference; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2013 |
Ocular surface evaluation in patients treated with a fixed combination of prostaglandin analogues with 0.5% timolol maleate topical monotherapy: a randomized clinical trial.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; HLA-DR Antigens; Humans; Immunohistochemistry; Interleukin-6; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Single-Blind Method; Timolol; Travoprost; Treatment Outcome | 2013 |
Safety and efficacy of bimatoprost/timolol fixed combination in Chinese patients with open-angle glaucoma or ocular hypertension.
Topics: Adolescent; Adult; Aged; Amides; Bimatoprost; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Timolol; Young Adult | 2014 |
Bimatoprost 0.03%/timolol 0.5% preservative-free ophthalmic solution versus bimatoprost 0.03%/timolol 0.5% ophthalmic solution (Ganfort) for glaucoma or ocular hypertension: a 12-week randomised controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Therapeutic Equivalency; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2014 |
Efficacy, safety, and tolerability of preservative-free fixed combination of tafluprost 0.0015%/timolol 0.5% versus concomitant use of the ingredients.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F; Timolol; Young Adult | 2014 |
Effect of early treatment with aqueous suppressants on Ahmed glaucoma valve implantation outcomes.
Topics: Adult; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Logistic Models; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2014 |
Long term IOP lowering efficacy of bimatoprost/timolol fixed combination: a 12 month prospective study.
Topics: Aged; Amides; Bimatoprost; Cloprostenol; Drug Combinations; Female; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Timolol; Treatment Outcome | 2013 |
Efficacy and tolerability of fixed-combination brinzolamide/timolol in Latin American patients with open-angle glaucoma or ocular hypertension previously on brimonidine/timolol fixed combination.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latin America; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Research Design; Sulfonamides; Thiazines; Timolol; United States | 2014 |
The Efficacy of a Latanoprost/Timolol Fixed Combination Versus Latanoprost and Timolol Gel-forming Solution Unfixed Combination on Daytime Intraocular Pressure.
Topics: Aged; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome | 2016 |
A 6-month study comparing efficacy, safety, and tolerability of the preservative-free fixed combination of tafluprost 0.0015% and timolol 0.5% versus each of its individual preservative-free components.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Comparison of the effects of bimatoprost and a fixed combination of latanoprost and timolol on 24-hour blood and ocular perfusion pressures: the results of a randomized trial.
Topics: Adult; Aged; Amides; Analysis of Variance; Antihypertensive Agents; Bimatoprost; Blood Pressure; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2015 |
Short-term effect of topical brinzolamide 1%-timolol 0.5% fixed combination on human central corneal thickness.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Capsule Opacification; Carbonic Anhydrase Inhibitors; Clonidine; Cornea; Corneal Pachymetry; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lasers, Solid-State; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2015 |
Additive Intraocular Pressure-Lowering Effects of the Rho Kinase Inhibitor Ripasudil (K-115) Combined With Timolol or Latanoprost: A Report of 2 Randomized Clinical Trials.
Topics: Aged; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Isoquinolines; Japan; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; rho-Associated Kinases; Severity of Illness Index; Sulfonamides; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2015 |
Effects of Switching from Timolol to Brimonidine in Prostaglandin Analog and Timolol Combination Therapy.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins, Synthetic; Timolol; Treatment Outcome | 2015 |
Fixed Combination of Travoprost and Timolol Maleate Reduces Intraocular Pressure in Japanese Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: A Prospective Multicenter Open-Label Study.
Topics: Adult; Aged; Aged, 80 and over; Cloprostenol; Drug Combinations; Drug Substitution; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Japan; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol; Tonometry, Ocular | 2015 |
Effects of Topical Bimatoprost 0.01% and Timolol 0.5% on Circadian IOP, Blood Pressure and Perfusion Pressure in Patients with Glaucoma or Ocular Hypertension: A Randomized, Double Masked, Placebo-Controlled Clinical Trial.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Bimatoprost; Blood Pressure; Circadian Rhythm; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol; Tonometry, Ocular; Treatment Outcome | 2015 |
Latanoprostene Bunod 0.024% versus Timolol Maleate 0.5% in Subjects with Open-Angle Glaucoma or Ocular Hypertension: The APOLLO Study.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Young Adult | 2016 |
Comparison of Latanoprostene Bunod 0.024% and Timolol Maleate 0.5% in Open-Angle Glaucoma or Ocular Hypertension: The LUNAR Study.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Visual Acuity; Young Adult | 2016 |
Preservative-free tafluprost in the treatment of open-angle glaucoma or ocular hypertension in India: a phase III clinical trial.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; India; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prostaglandins F; Prostaglandins, Synthetic; Timolol | 2016 |
Comparison of dorzolamide/timolol vs brinzolamide/brimonidine fixed combination therapy in the management of primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Efficacy of Latanoprostene Bunod 0.024% Compared With Timolol 0.5% in Lowering Intraocular Pressure Over 24 Hours.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 2016 |
Preventive Dorzolamide-Timolol for Rising Intraocular Pressure During Steep Trendelenburg Position Surgery.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Combinations; Eye; Female; Head-Down Tilt; Humans; Intraocular Pressure; Intraoperative Complications; Laparoscopy; Male; Middle Aged; Monitoring, Intraoperative; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2016 |
Effects of perioperative topical dorzolamide hydrochloride-timolol maleate administration on incidence and severity of postoperative ocular hypertension in dogs undergoing cataract extraction by phacoemulsification.
Topics: Animals; Antihypertensive Agents; Cataract Extraction; Dog Diseases; Dogs; Drug Combinations; Ocular Hypertension; Perioperative Care; Postoperative Complications; Sulfonamides; Thiophenes; Timolol | 2016 |
24-Hour Efficacy and Ocular Surface Health with Preservative-Free Tafluprost Alone and in Conjunction with Preservative-Free Dorzolamide/Timolol Fixed Combination in Open-Angle Glaucoma Patients Insufficiently Controlled with Preserved Latanoprost Monothe
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins F; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Adherence to Fixed-Combination Versus Unfixed Travoprost 0.004%/Timolol 0.5% for Glaucoma or Ocular Hypertension: A Randomized Trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Compliance; Single-Blind Method; Time Factors; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2017 |
The 24-Hour Effects of Brinzolamide/Brimonidine Fixed Combination and Timolol on Intraocular Pressure and Ocular Perfusion Pressure.
Topics: Aged; Blood Pressure; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2017 |
Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma.
Topics: Acetazolamide; Aged; Antihypertensive Agents; Dexamethasone; Drug Combinations; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preoperative Care; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Treatment Outcome | 2017 |
Intraocular pressure-lowering efficacy of brinzolamide 1%/timolol 0.5% fixed combination compared with brinzolamide 1% and timolol 0.5%.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Visual Acuity | 2008 |
Long-term efficacy and safety of bimatoprost for intraocular pressure lowering in glaucoma and ocular hypertension: year 4.
Topics: Amides; Analysis of Variance; Bimatoprost; Cloprostenol; Conjunctival Diseases; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Treatment Outcome; Visual Acuity | 2008 |
Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Pain; Pilocarpine; Prostaglandins F, Synthetic; Timolol; Treatment Outcome; Vision Disorders | 2008 |
Intraocular pressure control with latanoprost/timolol and travoprost/timolol fixed combinations : a retrospective, multicentre, cross-sectional study.
Topics: Adult; Aged; Cloprostenol; Cross-Sectional Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Timolol; Travoprost | 2008 |
A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2008 |
An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2008 |
Comparing diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure in patients receiving latanoprost monotherapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular | 2009 |
Efficacy and safety of latanoprost in eyes with uveitic glaucoma.
Topics: Adult; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Uveitis, Anterior; Uveitis, Intermediate; Visual Acuity | 2009 |
Pneumatic trabeculoplasty vs latanoprost as adjunctive therapy to timolol in primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Trabeculectomy; Treatment Outcome; Visual Acuity | 2009 |
24-hour intraocular pressure and blood pressure levels with latanoprost/timolol fixed combination versus timolol.
Topics: Aged; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2009 |
Dorzolamide-timolol combination and retinal vessel oxygen saturation in patients with glaucoma or ocular hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Oximetry; Oxygen; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Young Adult | 2009 |
Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Switching from concomitant latanoprost 0.005% and timolol 0.5% to a fixed combination of travoprost 0.004%/timolol 0.5% in patients with primary open-angle glaucoma and ocular hypertension: a 6-month, multicenter, cohort study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Cohort Studies; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Tears; Time Factors; Timolol; Travoprost | 2009 |
Using diurnal intraocular pressure fluctuation to assess the efficacy of fixed-combination latanoprost/timolol versus latanoprost or timolol monotherapy.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2010 |
Effect of dorzolamide and timolol on ocular pressure: blood flow relationship in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Interferometry; Intraocular Pressure; Laser-Doppler Flowmetry; Lasers; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2010 |
The safety and efficacy of bimatoprost/timolol fixed combination: a 1-year double-masked, randomized parallel comparison to its individual components in patients with glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
A comparison of bimatoprost 0.03% versus the fixed-combination of latanoprost 0.005% and timolol 0.5% in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label trial.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Blood Pressure; Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2009 |
The ability of short-wavelength automated perimetry to predict conversion to glaucoma.
Topics: Aged; Antihypertensive Agents; Betaxolol; Double-Blind Method; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Nerve Fibers; Ocular Hypertension; Optic Nerve Diseases; Prospective Studies; Retinal Ganglion Cells; Timolol; Vision Disorders; Visual Field Tests; Visual Fields | 2010 |
Short-term tolerability of once-daily timolol hemihydrate 0.5%, timolol maleate in sorbate 0.5%, and generic timolol maleate gel-forming solution 0.5% in glaucoma and/or ocular hypertension: a prospective, randomized, double-masked, active-controlled, thr
Topics: Adrenergic beta-Antagonists; Aged; Anterior Chamber; Cross-Over Studies; Double-Blind Method; Drugs, Generic; Female; Gels; Glaucoma; Humans; Intraocular Pressure; Irritants; Male; Ocular Hypertension; Pharmaceutical Solutions; Prospective Studies; Therapeutic Equivalency; Timolol; Vision Disorders; Visual Acuity | 2009 |
Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2010 |
Fixed combination of latanoprost and timolol vs individual components for primary open-angle glaucoma or ocular hypertension: a randomized, double-masked study.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2010 |
Efficacy and mechanisms of intraocular pressure reduction with latanoprost and timolol in participants with ocular hypertension: a comparison of 1 and 6 weeks of treatment.
Topics: Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sclera; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome; Uvea | 2010 |
Predictors of additional intraocular pressure reduction in patients changed to latanoprost/timolol fixed combination.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prognosis; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome; Young Adult | 2010 |
Effect of brimonidine/timolol fixed combination on preventing the short-term intraocular pressure increase after intravitreal injection of ranibizumab.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Humans; Injections, Intralesional; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebo Effect; Quinoxalines; Ranibizumab; Timolol; Treatment Outcome; Vitreous Body | 2010 |
Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol.
Topics: Aged; Aged, 80 and over; Algorithms; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dosage Forms; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2010 |
Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
[Evaluation of the effect of bimatoprost/timolol fixed combination on ocular blood flow in patients with ocular hypertension using colour Doppler imaging. Preliminary study].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Eye; Female; Humans; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Regional Blood Flow; Timolol; Ultrasonography, Doppler, Color | 2010 |
Intraocular pressure-lowering efficacy of brinzolamide when added to travoprost/timolol fixed combination as adjunctive therapy.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Visual Acuity | 2012 |
Control of intraocular pressure and fluctuation with fixed-combination brimonidine-timolol versus brimonidine or timolol monotherapy.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Double-Blind Method; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Timolol; Tonometry, Ocular | 2011 |
Observational study of patients switched to the fixed travoprost 0.004%/timolol 0.5% combination in Croatia.
Topics: Antihypertensive Agents; Cloprostenol; Croatia; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Timolol; Travoprost; Treatment Outcome | 2010 |
Effect of a fixed brimonidine-timolol combination on intraocular pressure after phacoemulsification.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cataract Extraction; Double-Blind Method; Drug Combinations; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Prospective Studies; Quinoxalines; Time Factors; Timolol | 2011 |
Intraocular pressure changes in the contralateral eye after topical treatment: does an "ophthalmotonic consensual reaction" exist?
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Timolol | 2010 |
[Effect on ocular blood flow of Combigan® versus placebo in patients with ocular hypertension].
Topics: Aged; Brimonidine Tartrate, Timolol Maleate Drug Combination; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Regional Blood Flow; Retinal Vessels; Timolol; Ultrasonography, Doppler, Color; Vascular Resistance | 2011 |
Timolol versus brinzolamide added to travoprost in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2011 |
Travoprost 0.004%/timolol 0.5%-fixed combination with and without benzalkonium chloride: a prospective, randomized, doubled-masked comparison of safety and efficacy.
Topics: Aged; Antihypertensive Agents; Benzalkonium Compounds; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Japan; Logistic Models; Male; Middle Aged; Ocular Hypertension; Polymers; Prospective Studies; Timolol; Travoprost; United States | 2011 |
Ocular hypotensive effect of oral palmitoyl-ethanolamide: a clinical trial.
Topics: Administration, Oral; Aged; Amides; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Endocannabinoids; Ethanolamines; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Palmitic Acids; Prospective Studies; Tablets; Timolol; Visual Acuity; Visual Fields | 2011 |
24-Hour intraocular pressure control between travoprost/timolol fixed combination, latanoprost/ timolol fixed combination and standard timolol in primary open angle glaucoma and ocular hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Time Factors; Timolol; Travoprost; Treatment Outcome; Young Adult | 2011 |
[Double-masked, phase III comparative study of the combination ophthalmic solution of the 1% dorzolamide hydrochloride/0.5% timolol maleate (MK-0507A) in patients with glaucoma and ocular hypertension].
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2011 |
Travoprost 0.004%/timolol 0.5% fixed combination in patients transitioning from fixed or unfixed bimatoprost 0.03%/timolol 0.5%.
Topics: Adult; Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol; Travoprost | 2011 |
Comparative efficacy and safety of the fixed versus unfixed combination of latanoprost and timolol in Chinese patients with open-angle glaucoma or ocular hypertension.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; China; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prevalence; Prostaglandins F, Synthetic; Retrospective Studies; Time Factors; Timolol; Treatment Outcome; Young Adult | 2011 |
[The influence of the Travalert(®) dosing aid on medical treatment compliance and the quality of life of glaucoma patients].
Topics: Administration, Ophthalmic; Aged; Anxiety; Cloprostenol; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Humans; Instillation, Drug; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quality of Life; Reminder Systems; Surveys and Questionnaires; Timolol; Travoprost | 2011 |
Ocular hypotensive effects and safety over 3 months of switching from an unfixed combination to latanoprost 0.005%/timolol maleate 0.5% fixed combination.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Surveys and Questionnaires; Timolol; Tonometry, Ocular; Treatment Outcome | 2011 |
Efficacy of single glaucoma drug in combined timolol XE, latanoprost and brinzolamide therapy: a discontinuation study.
Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol | 2012 |
Randomized clinical trial of the efficacy and safety of preservative-free tafluprost and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2012 |
Diurnal and nocturnal variations in aqueous humor dynamics of patients with ocular hypertension undergoing medical therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cornea; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sphygmomanometers; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography | 2012 |
Efficacy of single glaucoma medication in combined latanoprost and timolol XE therapy in patients with open-angle glaucoma and ocular hypertension: a discontinuation study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sample Size; Substance Withdrawal Syndrome; Timolol; Treatment Outcome | 2012 |
Fixed-combination brimonidine-timolol versus latanoprost in glaucoma and ocular hypertension: a 12-week, randomized, comparison study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Time Factors; Timolol; Treatment Outcome | 2012 |
Benzalkonium chloride induces anterior chamber inflammation in previously untreated patients with ocular hypertension as measured by flare meter: a randomized clinical trial.
Topics: Adult; Aged; Antihypertensive Agents; Aqueous Humor; Benzalkonium Compounds; Blood-Aqueous Barrier; Diagnostic Techniques, Ophthalmological; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Single-Blind Method; Timolol; Uveitis, Anterior | 2012 |
A double-masked randomized crossover study comparing the effect of latanoprost/timolol and brimonidine/timolol fixed combination on intraocular pressure and ocular blood flow in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Time Factors; Timolol; Ultrasonography, Doppler, Color | 2012 |
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimonidine Tartrate; Chemoprevention; Clonidine; Drug Combinations; Female; Humans; Hypotonic Solutions; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2012 |
Three-month evaluation of dorzolamide hydrochloride/timolol maleate fixed-combination eye drops versus the separate use of both drugs.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
Adherence improvement in Dutch glaucoma patients: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Drug Combinations; Drug Monitoring; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Netherlands; Ocular Hypertension; Ophthalmic Solutions; Patient Compliance; Patient Education as Topic; Surveys and Questionnaires; Timolol; Tonometry, Ocular; Travoprost | 2013 |
[Phase III clinical trial of brimonidine in patients with primary open-angle glaucoma and ocular hypertension--comparison of the effects of brimonidine monotherapy versus timolol monotherapy, or combination brimonidine/prostaglandins therapy versus combin
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins; Quinoxalines; Timolol; Treatment Outcome | 2012 |
The effect of latanoprost compared with timolol in African-American, Asian, Caucasian, and Mexican open-angle glaucoma or ocular hypertensive patients.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Asia; Black People; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Mexico; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; White People | 2002 |
One-year, randomized study comparing bimatoprost and timolol in glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Amides; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Humans; Hyperemia; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Safety; Timolol; Treatment Outcome | 2002 |
Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2002 |
The safety and efficacy of timolol 0.5% in xanthan gum versus timolol gel forming solution 0.5%.
Topics: Adrenergic beta-Antagonists; Adult; Anterior Eye Segment; Conjunctiva; Gels; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Ocular Hypertension; Polysaccharides, Bacterial; Prospective Studies; Safety; Single-Blind Method; Solutions; Staining and Labeling; Timolol; Visual Acuity | 2002 |
A comparison of the fixed combination of latanoprost and timolol with its individual components.
Topics: Aged; Circadian Rhythm; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2002 |
A randomised, double masked, multicentre clinical trial comparing bimatoprost and timolol for the treatment of glaucoma and ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Timolol; Treatment Outcome | 2003 |
Projected impact of travoprost versus both timolol and latanoprost on visual field deficit progression and costs among black glaucoma subjects.
Topics: Aged; Antihypertensive Agents; Black People; Cloprostenol; Disease Progression; Double-Blind Method; Drug Costs; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Travoprost; United States; Vision Disorders; Visual Fields | 2002 |
Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2003 |
Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2003 |
The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2003 |
Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2003 |
Efficacy and safety of timolol maleate/latanoprost fixed combination versus timolol maleate and brimonidine given twice daily.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Safety; Timolol | 2003 |
Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Twenty-four-hour diurnal curve comparison of commercially available latanoprost 0.005% versus the timolol and dorzolamide fixed combination.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
[Efficacy and safety of substituting a twice-daily regimen of timolol with a single daily instillation of nonpreserved beta-blocker in patients with chronic glaucoma or ocular hypertension].
Topics: Adrenergic beta-Antagonists; Aged; Aqueous Humor; Chronic Disease; Circadian Rhythm; Comorbidity; Drug Administration Schedule; Female; Glaucoma; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Acceptance of Health Care; Prospective Studies; Safety; Timolol | 2003 |
A six-week, parallel, randomized, double-blind study comparing the efficacy and safety of the 0.5% timolol/2.0% MK-507 combination b.i.d. to the concomitant administration of 0.5% timolol b.i.d. and 2.0% MK-507 b.i.d.
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Sulfonamides; Thiophenes; Timolol | 2003 |
A 3-month randomized controlled trial of bimatoprost (LUMIGAN) versus combined timolol and dorzolamide (Cosopt) in patients with glaucoma or ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
Pooled-data analysis of three randomized, double-masked, six-month studies comparing intraocular pressure-reducing effects of latanoprost and timolol in patients with ocular hypertension.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Retrospective Studies; Timolol; Treatment Outcome | 2003 |
Rate of response to latanoprost or timolol in patients with ocular hypertension or glaucoma.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Resistance; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2003 |
A 12 week study comparing the fixed combination of latanoprost and timolol with the concomitant use of the individual components in patients with open angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2004 |
Efficacy and tolerability of the dorzolamide 2%/timolol 0.5% combination (COSOPT) versus 0.005% (XALATAN) in the treatment of ocular hypertension or glaucoma: results from two randomized clinical trials.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
24-Hour IOP control with once-daily bimatoprost, timolol gel-forming solution, or latanoprost: a 1-month, randomized, comparative clinical trial.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2004 |
Two-year double-masked comparison of bimatoprost with timolol in patients with glaucoma or ocular hypertension.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2004 |
Efficacy and safety of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Efficacy and safety of the latanoprost/timolol maleate fixed combination vs concomitant brimonidine and latanoprost therapy.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2004 |
Brimonidine 0.2% vs unoprostone 0.15% both added to timolol maleate 0.5% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dinoprost; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Timolol; Treatment Outcome | 2005 |
Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2004 |
A 12-month, multicenter, randomized, double-masked, parallel-group comparison of timolol-LA once daily and timolol maleate ophthalmic solution twice daily in the treatment of adults with glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Delayed-Action Preparations; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol; Treatment Outcome | 2004 |
A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, evaluator masked, multicentre study in Europe.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Europe; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Timolol; Treatment Outcome | 2004 |
Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5%.
Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Comparison of latanoprost with fixed-combination dorzolamide and timolol in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label, parallel-group, multicenter study in Latin America.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Low incidence of iris pigmentation and eyelash changes in 2 randomized clinical trials with unoprostone isopropyl 0.15%.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Betaxolol; Dinoprost; Double-Blind Method; Eye Color; Eyelashes; Female; Glaucoma, Open-Angle; Hair Color; Humans; Hyperpigmentation; Incidence; Intraocular Pressure; Iris; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Photography; Timolol | 2004 |
Comparison of the nocturnal effects of once-daily timolol and latanoprost on intraocular pressure.
Topics: Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sleep; Supine Position; Timolol; Tonometry, Ocular | 2004 |
Short term efficacy and safety in glaucoma patients changed to the latanoprost 0.005%/timolol maleate 0.5% fixed combination from monotherapies and adjunctive therapies.
Topics: Aged; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Failure; Treatment Outcome | 2004 |
Concomitant administration of travoprost and brinzolamide versus fixed latanoprost/timolol combined therapy: three-month comparison of efficacy and safety.
Topics: Cloprostenol; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Travoprost | 2004 |
Switching from latanoprost to fixed-combination latanoprost-timolol: a 21-day, randomized, double-masked, active-control study in patients with glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2004 |
[A multicentre, observative, non-invasive study of the tolerance of NYOLOL gel 0,1% in ocular hypertensive patients].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Administration Schedule; Female; Gels; Humans; Male; Middle Aged; Observation; Ocular Hypertension; Prospective Studies; Severity of Illness Index; Timolol | 2004 |
Intraocular pressure and safety in glaucoma patients switching to latanoprost/timolol maleate fixed combination from mono- and adjunctive therapies.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Safety; Timolol; Tonometry, Ocular; Treatment Outcome | 2004 |
Interleukin-1beta tear concentration in glaucomatous and ocular hypertensive patients treated with preservative-free nonselective beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Conjunctival Diseases; Cross-Over Studies; Enzyme-Linked Immunosorbent Assay; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Interleukin-1; Intraocular Pressure; Keratitis; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Single-Blind Method; Tears; Timolol | 2005 |
Association between low plasma levels of ophthalmic timolol and haemodynamics in glaucoma patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Exercise Test; Female; Glaucoma; Heart Rate; Hemodynamics; Humans; Hydrogels; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pulse; Tilt-Table Test; Timolol; Vascular Resistance | 2005 |
Efficacy of the dorzolamide/timolol fixed combination versus latanoprost in the treatment of ocular hypertension or glaucoma: combined analysis of pooled data from two large randomized observer and patient-masked studies.
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
The safety and efficacy of travoprost 0.004%/timolol 0.5% fixed combination ophthalmic solution.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost; Treatment Outcome | 2005 |
Efficacy and safety of a fixed combination of travoprost 0.004%/timolol 0.5% ophthalmic solution once daily for open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Travoprost; Treatment Outcome | 2005 |
Brimonidine and timolol fixed-combination therapy versus monotherapy: a 3-month randomized trial in patients with glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Timolol; Treatment Outcome | 2005 |
A three-month, multicenter, double-masked study of the safety and efficacy of travoprost 0.004%/timolol 0.5% ophthalmic solution compared to travoprost 0.004% ophthalmic solution and timolol 0.5% dosed concomitantly in subjects with open angle glaucoma or
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Travoprost; Treatment Outcome | 2005 |
A randomized trial assessing dorzolamide in patients with glaucoma who are younger than 6 years.
Topics: Antihypertensive Agents; Child, Preschool; Double-Blind Method; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Choroid; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Regional Blood Flow; Regression Analysis; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2005 |
A 6-month assessment of bimatoprost 0.03% vs timolol maleate 0.5%: hypotensive efficacy, macular thickness and flare in ocular-hypertensive and glaucoma patients.
Topics: Adult; Amides; Anterior Chamber; Antihypertensive Agents; Bimatoprost; Cloprostenol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Macula Lutea; Ocular Hypertension; Prospective Studies; Timolol; Treatment Outcome | 2007 |
A 12-week, randomized, double-masked, multicenter study of the fixed combination of latanoprost and timolol in the evening versus the individual components.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2006 |
Comparative analysis of the efficacy and safety of latanoprost, travoprost and the fixed combination timolol-dorzolamide; a prospective, randomized, masked, cross-over design study.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Latanoprost; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2005 |
Efficacy of latanoprost or fixed-combination latanoprost-timolol in patients switched from a combination of timolol and a nonprostaglandin medication.
Topics: Adult; Aged; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retreatment; Timolol; Treatment Outcome | 2006 |
Comparison of a non-preserved 0.1% T-Gel eye gel (single dose unit) with a preserved 0.1% T-Gel eye gel (multidose) in ocular hypertension and glaucomatous patients.
Topics: Adrenergic beta-Antagonists; Aged; Analysis of Variance; Antihypertensive Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol | 2006 |
Improved systemic safety and risk-benefit ratio of topical 0.1% timolol hydrogel compared with 0.5% timolol aqueous solution in the treatment of glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Biological Availability; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Risk Assessment; Spirometry; Tilt-Table Test; Timolol; Visual Acuity | 2006 |
A 6-week, double-masked, parallel-group study of the efficacy and safety of travoprost 0.004% compared with latanoprost 0:005%/timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2006 |
A randomized, investigator-masked, 4-week study comparing timolol maleate 0.5%, brinzolamide 1%, and brimonidine tartrate 0.2% as adjunctive therapies to travoprost 0.004% in adults with primary open-angle glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiazines; Timolol; Travoprost | 2006 |
An evaluation of the rate of nonresponders to latanoprost therapy.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Resistance; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Timolol; Tonometry, Ocular | 2006 |
Twice-daily 0.2% brimonidine-0.5% timolol fixed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: a 12-month randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Timolol; Tonometry, Ocular; Treatment Outcome | 2006 |
Comparison of the efficacy and safety of travoprost with a fixed-combination of dorzolamide and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Travoprost | 2006 |
Phase III long-term study and comparative clinical study of nipradilol ophthalmic solution in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Propanolamines; Timolol; Vasodilator Agents | 2006 |
Comparison of the ocular hypotensive effects of bimatoprost and timolol-dorzolamide combination in patients with elevated intraocular pressure: a 6-month study.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2007 |
Phase III long-term study and comparative clinical study of nipradilol ophthalmic solution in patients with primary open-angle glaucoma and ocular hypertension. Part 2.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Double-Blind Method; Electrocardiography; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Propanolamines; Timolol | 2006 |
Latanoprost versus timolol gel-forming solution once daily in primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2007 |
Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure.
Topics: Aged; Brimonidine Tartrate; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2007 |
Comparison of the effects of bimatoprost and a fixed combination of latanoprost and timolol on circadian intraocular pressure.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome | 2007 |
Intraocular pressure elevation within the first 24 hours after cataract surgery in patients with glaucoma or exfoliation syndrome.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Timolol; Tonometry, Ocular | 2008 |
Twenty-four-hour efficacy of the brimonidine/timolol fixed combination versus therapy with the unfixed components.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Time Factors; Timolol; Treatment Outcome | 2008 |
Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Child; Child, Preschool; Female; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Premedication; Prospective Studies; Timolol; Tonometry, Ocular; Visual Acuity | 2008 |
Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Capsulorhexis; Cataract; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Prosthesis Design; Sulfonamides; Thiophenes; Timolol | 2007 |
Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat.
Topics: Acetazolamide; Acetylcholine; Administration, Topical; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chondroitin; Chondroitin Sulfates; Double-Blind Method; Drug Combinations; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular | 2007 |
The effect of ocular hypotensive agents on macula.
Topics: Administration, Topical; Adult; Aged; Amides; Bimatoprost; Cloprostenol; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Latanoprost; Lipids; Macula Lutea; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Travoprost; Visual Acuity; Visual Field Tests | 2007 |
Success rates for switching to dorzolamide/timolol fixed combination in timolol responders who are insufficiently controlled by latanoprost monotherapy.
Topics: Aged; Antihypertensive Agents; Cohort Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Satisfaction; Prospective Studies; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Treatment Outcome | 2008 |
Comparison of the 24-hour intraocular pressure-lowering effects of latanoprost and dorzolamide/timolol fixed combination after 2 and 6 months of treatment.
Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Therapeutic Equivalency; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2008 |
Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Postoperative Care; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
Dorzolamide/timolol fixed combination versus latanoprost/timolol fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
Effectiveness and safety of dorzolamide-timolol alone or combined with latanoprost in open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Canada; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
The comparative multiple-dose intraocular pressure responses of nadolol and timolol in glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Nadolol; Ocular Hypertension; Propanolamines; Timolol | 1982 |
Diacetyl nadolol: 3-month ocular hypotensive effect in glaucomatous eyes.
Topics: Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Nadolol; Ocular Hypertension; Propanolamines; Timolol | 1983 |
A combination of oral and topical beta-blockers with additive effects on intraocular pressure.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Propranolol; Random Allocation; Timolol | 1983 |
Diacetyl derivative of nadolol. I. Ocular pharmacology and short-term ocular hypotensive effect in glaucomatous eyes.
Topics: Absorption; Adult; Animals; Clinical Trials as Topic; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Humans; Hydrolysis; Male; Nadolol; Ocular Hypertension; Propanolamines; Rabbits; Timolol | 1982 |
The effect of topical beta-adrenoceptor blocking agents on pulsatile ocular blood flow.
Topics: Adrenergic beta-Antagonists; Betaxolol; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Pulsatile Flow; Time Factors; Timolol | 1995 |
A double-masked, randomized 1-year study comparing dorzolamide (Trusopt), timolol, and betaxolol. International Dorzolamide Study Group.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1995 |
Comparative phase III clinical trial of latanoprost and timolol in patients with elevated intraocular pressure.
Topics: Circadian Rhythm; Double-Blind Method; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 1995 |
[Hypotensive action of 0.5% carteolol versus 0.1% timolol in patients with intraocular hypertension].
Topics: Adult; Carteolol; Double-Blind Method; Female; Humans; Male; Ocular Hypertension; Prospective Studies; Timolol | 1995 |
Additive effect of latanoprost, a prostaglandin F2 alpha analogue, and timolol in patients with elevated intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Conjunctiva; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 1994 |
Efficacy and safety of timolol/pilocarpine combination drops in glaucoma patients.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Timolol; Visual Acuity; Visual Fields | 1994 |
The efficacy of apraclonidine as an adjunct to timolol therapy. Apraclonidine Adjunctive Therapy Study Group.
Topics: Adrenergic alpha-Agonists; Chemotherapy, Adjuvant; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1995 |
A comparison of timolol maleate and levobunolol. Length of use per 5-ml bottle.
Topics: Aged; Aged, 80 and over; Chronic Disease; Drug Monitoring; Drug Packaging; Glaucoma, Open-Angle; Humans; Levobunolol; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1994 |
Longterm effect of topical beta-blockers on intraocular pressure and visual field sensitivity in ocular hypertension and chronic open-angle glaucoma.
Topics: Administration, Topical; Adult; Aged; Betaxolol; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol; Tonometry, Ocular; Visual Field Tests; Visual Fields | 1994 |
Diurnal variation in pulsatile ocular blood flow in normal and glaucomatous eyes.
Topics: Aged; Blood Flow Velocity; Blood Pressure; Circadian Rhythm; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pulsatile Flow; Timolol; Tonometry, Ocular | 1994 |
Effect of timolol vs. acetazolamide on sodium hyaluronate-induced rise in intraocular pressure after cataract surgery.
Topics: Acetazolamide; Administration, Oral; Adult; Aged; Aged, 80 and over; Cataract Extraction; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Timolol | 1994 |
Double-masked comparative study of UF-021 and timolol ophthalmic solutions in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Blood Pressure; Dinoprost; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1993 |
Combined timolol and pilocarpine vs pilocarpine alone and timolol alone in the treatment of glaucoma.
Topics: Administration, Topical; Adult; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Timolol; Tonometry, Ocular | 1994 |
The effect of betaxolol and timolol on postoperative intraocular pressure.
Topics: Betaxolol; Cataract Extraction; Double-Blind Method; Humans; Intraocular Pressure; Lenses, Intraocular; Ocular Hypertension; Ophthalmic Solutions; Timolol; Tonometry, Ocular | 1993 |
Double-masked three-period crossover investigation of timolol in control of raised intraocular pressure.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Humans; Ocular Hypertension; Timolol | 1993 |
Comparison of apraclonidine and timolol in chronic open-angle glaucoma. A three-month study.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Clonidine; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol | 1993 |
[Prevention of IOP rise following laser iridectomy with topical timolol and indomethacin].
Topics: Female; Glaucoma, Angle-Closure; Humans; Indomethacin; Iris; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Premedication; Prospective Studies; Timolol | 1993 |
Serial administration of adrenergic antagonist and agonist ("pulsatile therapy") reduces the incidence of long-term drift to timolol in humans.
Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Drug Administration Schedule; Drug Tolerance; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1996 |
Around-the-clock intraocular pressure reduction with once-daily application of latanoprost by itself or in combination with timolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Chronic Disease; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Posture; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 1996 |
Timolol hemihydrate vs timolol maleate to treat ocular hypertension and open-angle glaucoma.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Chronic Disease; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 1996 |
A six-month, randomized, double-masked study comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension. The Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prostaglandins F, Synthetic; Timolol; Visual Acuity | 1996 |
Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: a six-month masked, multicenter trial in the United States. The United States Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Conjunctiva; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Hyperemia; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prostaglandins F, Synthetic; Timolol; United States | 1996 |
Relating spontaneous adverse experience reports to scores on a questionnaire querying tolerability.
Topics: Adult; Adverse Drug Reaction Reporting Systems; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1995 |
A six-week dose-response study of the ocular hypotensive effect of dorzolamide with a one-year extension. Dorzolamide Dose-Response Study Group.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 1996 |
A comparison of latanoprost and timolol in primary open-angle glaucoma and ocular hypertension. A 12-week study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Conjunctiva; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 1996 |
A 90-day study of the efficacy and side effects of 0.25% and 0.5% apraclonidine vs 0.5% timolol. Apraclonidine Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1996 |
A 6-month, randomized, double-masked comparison of latanoprost with timolol in patients with open angle glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Scandinavian and Nordic Countries; Timolol | 1996 |
A controlled clinical trial of dorzolamide: a single-centre subset of a multicentre study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pilot Projects; Safety; Sulfonamides; Thiophenes; Timolol | 1996 |
Early postoperative intraocular pressure pattern in glaucomatous and nonglaucomatous patients.
Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lenses, Intraocular; Male; Ocular Hypertension; Postoperative Period; Random Allocation; Risk Factors; Timolol | 1996 |
The effects of the beta-adrenergic-blocking agents, timolol and carteolol, on plasma lipids and lipoproteins in Japanese glaucoma patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carteolol; Cholesterol; Cholesterol, HDL; Female; Glaucoma, Open-Angle; Humans; Lipids; Lipoproteins; Male; Middle Aged; Ocular Hypertension; Phosphatidylcholine-Sterol O-Acyltransferase; Prospective Studies; Timolol | 1996 |
Increase of retinal nerve fiber layer thickness in ocular hypertensives with timolol therapy.
Topics: Double-Blind Method; Female; Humans; Male; Middle Aged; Models, Biological; Multivariate Analysis; Ocular Hypertension; Retina; Timolol | 1995 |
Increase of retinal vessel width in ocular hypertensives with timolol therapy.
Topics: Double-Blind Method; Fundus Oculi; Humans; Image Processing, Computer-Assisted; Models, Biological; Multivariate Analysis; Ocular Hypertension; Retinal Vessels; Timolol | 1995 |
Decrease of optic disc cupping and pallor of ocular hypertensives with timolol therapy.
Topics: Double-Blind Method; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Models, Biological; Multivariate Analysis; Ocular Hypertension; Optic Disk; Photography; Timolol; Treatment Outcome | 1995 |
Latanoprost, a prostaglandin analog, for glaucoma therapy. Efficacy and safety after 1 year of treatment in 198 patients. Latanoprost Study Groups.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Exfoliation Syndrome; Eye Color; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Timolol; Visual Acuity; Visual Fields | 1996 |
A comparative study of the effects of timolol and latanoprost on blood flow velocity of the retrobulbar vessels.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Blood Flow Velocity; Ciliary Body; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Artery; Ophthalmic Solutions; Orbit; Prospective Studies; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Artery; Timolol; Ultrasonography, Doppler, Color | 1996 |
Clinical experience with brimonidine 0.2% and timolol 0.5% in glaucoma and ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol; Treatment Outcome | 1996 |
Efficacy of silicone punctal plugs as adjuncts to topical pharmacotherapy of glaucoma--a pilot study. Punctal Plugs in Glaucoma Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Combined Modality Therapy; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Lacrimal Duct Obstruction; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Silicones; Timolol | 1996 |
Comparison of topical timolol gel to oral acetazolamide in the prophylaxis of viscoelastic-induced ocular hypertension after penetrating keratoplasty.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Gels; Humans; Hyaluronic Acid; Intraocular Pressure; Keratoplasty, Penetrating; Male; Ocular Hypertension; Postoperative Complications; Prospective Studies; Timolol | 1997 |
A comparison of Healon and Amvisc on the early postoperative pressure after extracapsular cataract extraction with implantation of posterior chamber lens.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Cataract Extraction; Female; Follow-Up Studies; Humans; Hyaluronic Acid; Intraocular Pressure; Lenses, Intraocular; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Period; Prospective Studies; Regression Analysis; Timolol | 1996 |
A comparison of dorzolamide and timolol in patients with pseudoexfoliation and glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
Validation of a questionnaire for comparing the tolerability of ophthalmic medications.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Eye Diseases; Female; Glaucoma, Open-Angle; Health Status Indicators; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Parasympathomimetics; Pilocarpine; Reproducibility of Results; Surveys and Questionnaires; Timolol | 1997 |
Effects on intraocular pressure and side effects of 0.005% latanoprost applied once daily, evening or morning. A comparison with timolol. Scandinavian Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 1995 |
Enhanced acute ocular hypotensive response to timolol with dexamethasone treatment.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Dexamethasone; Drug Synergism; Female; Glucocorticoids; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1997 |
Cardiovascular effects of topical carteolol hydrochloride and timolol maleate in patients with ocular hypertension and primary open-angle glaucoma. Night Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carteolol; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Visual Acuity | 1997 |
Clinical evaluation of UF-021 (Rescula; isopropyl unoprostone).
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Dinoprost; Drug Evaluation; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Timolol; Treatment Outcome | 1997 |
The effect of 0.5% timolol maleate on the ocular perfusion of ocular hypertensive patients by scanning laser flowmetry.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Blood Volume; Eye; Female; Humans; Male; Ocular Hypertension; Regional Blood Flow; Timolol | 1997 |
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Australia; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
A 1-year study of brimonidine twice daily in glaucoma and ocular hypertension. A controlled, randomized, multicenter clinical trial. Chronic Brimonidine Study Group.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pupil; Quinoxalines; Safety; Time Factors; Timolol; Treatment Outcome; Visual Acuity | 1997 |
Efficacy of carteolol hydrochloride 1% vs timolol maleate 0.5% in patients with increased intraocular pressure. Nocturnal Investigation of Glaucoma Hemodynamics Trial Study Group.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carteolol; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Treatment Outcome | 1997 |
Levobunolol 0.5% and timolol 0.5% to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Cataract; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Levobunolol; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Premedication; Prospective Studies; Timolol | 1997 |
Timolol gel versus acetazolamide in the prophylaxis of ocular hypertension after phacoemulsification.
Topics: Acetazolamide; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Delayed-Action Preparations; Double-Blind Method; Female; Gels; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Premedication; Prospective Studies; Timolol | 1997 |
Latanoprost. Two years' experience of its use in the United Kingdom. Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prostaglandins F, Synthetic; Safety; Timolol; United Kingdom | 1998 |
A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Quality of Life; Sulfonamides; Thiophenes; Timolol; Visual Fields | 1998 |
The efficacy and safety of dorzolamide as adjunctive therapy to timolol maleate gellan solution in patients with elevated intraocular pressure. Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Gels; Humans; Male; Middle Aged; Ocular Hypertension; Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
A double-masked, randomized, 1-year study comparing the corneal effects of dorzolamide, timolol, and betaxolol. Dorzolamide Corneal Effects Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Cell Count; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
Latanoprost treatment for glaucoma: effects of treating for 1 year and of switching from timolol. United States Latanoprost Study Group.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Eye Color; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Timolol | 1998 |
Clinical efficacy and safety of brinzolamide (Azopt), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 1998 |
The effect of timolol drops on respiratory function.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bronchoconstriction; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Male; Middle Aged; Ocular Hypertension; Peak Expiratory Flow Rate; Respiratory Mechanics; Timolol; Vital Capacity | 1998 |
Dark adaptation in early primary biliary cirrhosis.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Bronchoconstriction; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Humans; Middle Aged; Ocular Hypertension; Peak Expiratory Flow Rate; Respiratory Mechanics; Timolol; Vital Capacity | 1998 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol 0.5% given twice daily in patients with glaucoma or ocular hypertension. Brimonidine Study Group 2.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol | 1998 |
Additive effect of dorzolamide on aqueous humor flow in patients receiving long-term treatment with timolol.
Topics: Adrenergic beta-Antagonists; Aged; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Synergism; Female; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Direct costs of glaucoma management following initiation of medical therapy. A simulation model based on an observational study of glaucoma treatment in Germany.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Germany; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 1998 |
The effects of unoprostone isopropyl 0.12% and timolol maleate 0.5% on diurnal intraocular pressure.
Topics: Circadian Rhythm; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Safety; Timolol; Visual Acuity | 1998 |
Two-year safety study of dorzolamide as monotherapy and with timolol and pilocarpine. Dorzolamide Safety Study Group.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
Efficacy and safety of timolol solution once daily versus timolol gel in treating elevated intraocular pressure.
Topics: Blood Pressure; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Treatment Outcome; Visual Acuity | 1998 |
A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Brimonidine tartrate 0.2% twice daily vs timolol 0.5% twice daily: 1-year results in glaucoma patients. Brimonidine Study Group.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol; Treatment Outcome | 1999 |
Effects of carteolol and timolol on plasma lipid profiles in older women with ocular hypertension or primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Carteolol; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Lipids; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol | 1999 |
Pressure or progression?
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Brimonidine Tartrate; Disease Progression; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Timolol; Visual Fields | 1999 |
Patient preference, efficacy, and compliance with timolol maleate ophthalmic gel-forming solution versus timolol maleate ophthalmic solution in patients with ocular hypertension or open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Compliance; Patient Satisfaction; Single-Blind Method; Timolol | 1999 |
Diversity of response of optic nerve head circulation to timolol maleate in gel-forming solution.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Circulation; Blood Flow Velocity; Cross-Over Studies; Double-Blind Method; Eye Color; Female; Gels; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Optic Disk; Timolol | 1999 |
A comparison of the intraocular pressure-lowering effect of 0.5% timolol maleate and the docosanoid derivative of a PGF2 alpha metabolite, 0.12% unoprostone, in subjects with chronic open-angle glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Chronic Disease; Depression, Chemical; Dinoprost; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Time Factors; Timolol | 1999 |
Comparison of dorzolamide and pilocarpine as adjunctive therapy in patients with open-angle glaucoma and ocular hypertension.
Topics: Adjuvants, Pharmaceutic; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Parasympathomimetics; Patient Dropouts; Pilocarpine; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 1999 |
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1999 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 1999 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
Central nervous system and plasma lipid profiles associated with carteolol and timolol in postmenopausal black women.
Topics: Adrenergic beta-Antagonists; Aged; Black People; Brain; Carteolol; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postmenopause; Timolol; Visual Acuity | 1999 |
Efficacy and safety of timolol solution once daily vs timolol gel added to latanoprost.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Safety; Timolol; Treatment Outcome | 1999 |
Comparison of the intraocular pressure lowering effect of latanoprost and a fixed combination of timolol-pilocarpine eye drops in patients insufficiently controlled with beta adrenergic antagonists. French Latanoprost Study Group, and the Swedish Latanopr
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Timolol | 2000 |
Comparison of latanoprost monotherapy to dorzolamide combined with timolol in patients with glaucoma and ocular hypertension.A 3-month randomised study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
Adjunctive therapy with brinzolamide 1% ophthalmic suspension (Azopt) in patients with open-angle glaucoma or ocular hypertension maintained on timolol therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Timolol; Treatment Outcome | 2000 |
The long-term safety and efficacy of brinzolamide 1.0% (azopt) in patients with primary open-angle glaucoma or ocular hypertension. The Brinzolamide Long-Term Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Evaluation; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Timolol | 2000 |
Effects of topical nipradilol, a beta blocking agent with alpha blocking and nitroglycerin-like activities, on intraocular pressure and aqueous dynamics in humans.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aqueous Humor; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Propanolamines; Timolol | 2000 |
Ongoing clinical assessment of the safety profile and efficacy of brimonidine compared with timolol: year-three results. Brimonidine Study Group II.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Timolol; Vision Tests | 2000 |
Comparison of the effects of 0.5% timolol maleate, 2% carteolol hydrochloride, and 0.3% metipranolol on intraocular pressure and perimetry findings and evaluation of their ocular and systemic effects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carteolol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Metipranolol; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Treatment Outcome; Visual Field Tests; Visual Fields | 2000 |
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2000 |
Latanoprost versus timolol gel to prevent ocular hypertension after phacoemulsification and intraocular lens implantation.
Topics: Adrenergic beta-Antagonists; Aged; Anterior Chamber; Antihypertensive Agents; Cell Count; Double-Blind Method; Female; Gels; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2000 |
[The influence of 0.85% RS-timolol and 0.5% S-timolol on intraocular pressure and systemic arterial blood pressure, heart rate, ECG, expiratory capacity in patients with ocular hypertension and primary open-angle glaucoma].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Electrocardiography; Expiratory Reserve Volume; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Severity of Illness Index; Timolol | 1999 |
Short-term effect of latanoprost and timolol eye drops on tear fluid and the ocular surface in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Conjunctiva; Cornea; Double-Blind Method; Female; Fluorescent Dyes; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rose Bengal; Tears; Timolol; Treatment Outcome | 2000 |
Latanoprost: experience of 2-year treatment in Scandinavia.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Scandinavian and Nordic Countries; Timolol; Treatment Outcome | 2000 |
Effects of systemic beta-blocker therapy on the efficacy and safety of topical brimonidine and timolol. Brimonidine Study Groups 1 and 2.
Topics: Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Timolol | 2000 |
Clinical success and quality of life with brimonidine 0.2% or timolol 0.5% used twice daily in glaucoma or ocular t hypertension: a randomized clinical trial. Brimonidine Outcomes Study Group I.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quality of Life; Quinoxalines; Safety; Surveys and Questionnaires; Timolol; Treatment Outcome | 2000 |
The additive intraocular pressure-lowering effect of latanoprost 0.005% daily once and pilocarpine 2% t.i.d. in patients with open-angle glaucoma or ocular hypertension. a 6-month, randomized, multicenter study. German Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2000 |
Effect of timolol, latanoprost, and dorzolamide on circadian IOP in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
Long-term intraocular pressure-lowering efficacy and safety of timolol maleate gel-forming solution 0.5% compared with Timoptic XE 0.5% in a 12-month study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Treatment Outcome | 2000 |
Long-term effects of timolol therapy in ocular hypertension: a double-masked, randomised trial.
Topics: Adrenergic beta-Antagonists; Double-Blind Method; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Optic Disk; Prospective Studies; Risk Factors; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Fields | 2000 |
Comparison of the corneal effects of latanoprost, fixed combination latanoprost-timolol, and timolol: A double-masked, randomized, one-year study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cell Count; Double-Blind Method; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol | 2001 |
Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Anterior Eye Segment; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzalkonium Compounds; Blood-Aqueous Barrier; Capillary Permeability; Diclofenac; Double-Blind Method; Female; Fluorescein Angiography; Fluorometholone; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Macular Edema; Male; Ocular Hypertension; Preservatives, Pharmaceutical; Pseudophakia; Single-Blind Method; Timolol | 2001 |
The hypotensive efficacy of dorzolamide HCL-timolol maleate 0.50% vs concomitant use of the two drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Therapeutic Equivalency; Thiophenes; Timolol | 2000 |
Hypotensive efficacy in primary open-angle glaucoma and ocular hypertension: latanoprost in monotherapy vs timolol and dorzolamide in association.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2000 |
The effect on diurnal intraocular pressure of the fixed combination of latanoprost 0.005% and timolol 0.5% in patients with ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2001 |
Effect on intraocular pressure during 24 hours after repeated administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in patients with ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2001 |
Efficacy and tolerability of timolol maleate ophthalmic gel-forming solution versus timolol ophthalmic solution in adults with open-angle glaucoma or ocular hypertension: a six-month, double-masked, multicenter study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 2001 |
Intraindividual comparison of the effects of a fixed dorzolamide-timolol combination and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
Comparison of once- or twice-daily bimatoprost with twice-daily timolol in patients with elevated IOP : a 3-month clinical trial.
Topics: Adult; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Treatment Outcome; Visual Acuity; Visual Fields | 2001 |
Additive IOP-reducing effect of latanoprost in patients insufficiently controlled on timolol.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2001 |
Six-month comparison of bimatoprost once-daily and twice-daily with timolol twice-daily in patients with elevated intraocular pressure.
Topics: Adrenergic beta-Antagonists; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctiva; Double-Blind Method; Eye Color; Female; Glaucoma; Humans; Hyperemia; Intraocular Pressure; Iris; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2001 |
Effect of timolol 0.5% gel and solution on pulmonary function in older glaucoma patients.
Topics: Adrenergic beta-Antagonists; Aged; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lung; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Tonometry, Ocular; Vital Capacity | 2001 |
Comparison of the ocular hypotensive lipid AGN 192024 with timolol: dosing, efficacy, and safety evaluation of a novel compound for glaucoma management.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Hemodynamics; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2001 |
Intraocular pressure over 24 hours after repeated administration of latanoprost 0.005% or timolol gel-forming solution 0.5% in patients with ocular hypertension.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Female; Gels; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2001 |
Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2001 |
Treatment of intraocular pressure elevation after photorefractive keratectomy.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorometholone; Glucocorticoids; Humans; Intraocular Pressure; Lasers, Excimer; Male; Ocular Hypertension; Ophthalmic Solutions; Photorefractive Keratectomy; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2001 |
Comparison of the additive intraocular pressure-lowering effect of latanoprost and dorzolamide when added to timolol in patients with open-angle glaucoma or ocular hypertension: a randomized, open-label, multicenter study in Greece.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Travoprost compared with latanoprost and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prodrugs; Prostaglandins F, Synthetic; Safety; Timolol; Travoprost; Treatment Outcome | 2001 |
[Clinical evaluation of isopropyl unoprostone (Rescula), in the adjunctive treatment of primary open angle glaucoma].
Topics: Administration, Topical; Antihypertensive Agents; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2001 |
Lack of long-term drift in timolol's effectiveness in patients with ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Drug Tolerance; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol | 2001 |
Comparison of aqueous and gellan ophthalmic timolol with placebo on the 24-hour heart rate response in patients on treatment for glaucoma.
Topics: Adrenergic beta-Antagonists; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2001 |
Comparison of topical travoprost eye drops given once daily and timolol 0.5% given twice daily in patients with open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost; Treatment Outcome | 2001 |
Evaluation of travoprost as adjunctive therapy in patients with uncontrolled intraocular pressure while using timolol 0.5%.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Chemotherapy, Adjuvant; Cloprostenol; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Travoprost | 2001 |
A double-masked randomized comparison of the efficacy and safety of unoprostone with timolol and betaxolol in patients with primary open-angle glaucoma including pseudoexfoliation glaucoma or ocular hypertension. 6 month data.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Betaxolol; Dinoprost; Double-Blind Method; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pupil; Safety; Timolol; Visual Acuity; Visual Fields | 2002 |
[A comparison between latanoprost and timolol in treatment of patients with primary open-angle glaucoma and ocular hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2000 |
Comparison of travoprost 0.0015% and 0.004% with timolol 0.5% in patients with elevated intraocular pressure: a 6-month, masked, multicenter trial.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cloprostenol; Double-Blind Method; Drug Evaluation; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Travoprost; Treatment Outcome | 2002 |
A comparison of the efficacy and tolerability of 0.5% timolol maleate ophthalmic gel-forming solution QD and 0.5% levobunolol hydrochloride BID in patients with ocular hypertension or open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Cross-Over Studies; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Ocular Hypertension; Ophthalmic Solutions; Timolol | 2002 |
A comparison of once-daily morning vs evening dosing of concomitant latanoprost/timolol.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol | 2002 |
Latanoprost and timolol combination therapy vs monotherapy: one-year randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Safety; Timolol; Treatment Outcome | 2002 |
Tolerability and efficacy of dorzolamide versus acetazolamide added to timolol.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
Sezolamide: additivity to timolol twice daily.
Topics: Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 1992 |
Six week safety study of 2% MK-927 administered twice daily to ocular hypertensive volunteers.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol | 1992 |
Ocular hypertension: correlation of anterior chamber angle width and risk of progression to glaucoma.
Topics: Aged; Anterior Chamber; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Male; Middle Aged; Ocular Hypertension; Optic Disk; Risk Factors; Timolol; Visual Fields | 1992 |
Effects of timolol ophthalmic solution on the intra-ocular pressure rise induced by suxamethonium and tracheal intubation.
Topics: Adult; Aged; Double-Blind Method; Humans; Intubation, Intratracheal; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Ophthalmologic Surgical Procedures; Premedication; Succinylcholine; Timolol | 1992 |
The effect of Healon and timolol on early postoperative intraocular pressure after extracapsular cataract extraction with implantation of a posterior chamber lens.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cataract Extraction; Double-Blind Method; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Timolol; Tonometry, Ocular | 1992 |
[Intraocular pressure changes after Nd:YAG laser capsulotomy with preoperative use of timolol].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cataract Extraction; Child; Female; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Male; Middle Aged; Ocular Hypertension; Postoperative Period; Premedication; Timolol | 1991 |
Additive effect of 1% apraclonidine hydrochloride to nonselective beta-blockers.
Topics: Adrenergic alpha-Agonists; Clonidine; Double-Blind Method; Drug Synergism; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Ocular Hypertension; Prospective Studies; Random Allocation; Timolol | 1991 |
[Additive effect of timolol and the local carbonic anhydrase inhibitor MK-417 (sezolamide)].
Topics: Aged; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 1991 |
Evaluation of once-daily levobunolol 0.25% and timolol 0.25% therapy for increased intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Evaluation Studies as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1991 |
Adrenergic and adrenolytic effects on intraocular pressure.
Topics: Administration, Topical; Analysis of Variance; Drug Therapy, Combination; Epinephrine; Humans; Intraocular Pressure; Ocular Hypertension; Pindolol; Placebos; Timolol | 1991 |
A comparison of treated and untreated glaucoma suspects.
Topics: Aged; Female; Follow-Up Studies; Glaucoma; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Optic Disk; Prospective Studies; Retinal Hemorrhage; Survival Analysis; Timolol; Visual Fields | 1991 |
Effect of timolol maleate on the retinal circulation of human eyes with ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Blood Flow Velocity; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Photography; Random Allocation; Retinal Vein; Rheology; Timolol | 1990 |
Twelve-hour IOP control obtained by a single dose of timolol/pilocarpine combination eye drops.
Topics: Administration, Topical; Aged; Aged, 80 and over; Analysis of Variance; Chi-Square Distribution; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Pilocarpine; Time Factors; Timolol | 1990 |
Topical timolol and serum lipoproteins.
Topics: Administration, Topical; Aged; Aged, 80 and over; Female; Glaucoma; Humans; Lipoproteins; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol | 1990 |
Steady-state pattern electroretinogram following long term unilateral administration of timolol to ocular hypertensive subjects.
Topics: Aged; Electroretinography; Female; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Pattern Recognition, Visual; Prospective Studies; Timolol | 1990 |
Topical timolol and the human retinal circulation.
Topics: Fundus Oculi; Humans; Intraocular Pressure; Ocular Hypertension; Random Allocation; Regional Blood Flow; Retina; Rheology; Timolol | 1989 |
Timolol treatment prevents or delays glaucomatous visual field loss in individuals with ocular hypertension: a five-year, randomized, double-masked, clinical trial.
Topics: Adult; Aged; Demography; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Optic Disk; Timolol; Visual Fields | 1989 |
A comparison of the efficacy of betaxolol and timolol in ocular hypertension with or without adrenaline.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Betaxolol; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Humans; Male; Middle Aged; Ocular Hypertension; Propanolamines; Random Allocation; Timolol | 1989 |
Is it worthwhile to add dipivefrin HCl 0.1% to topical beta 1-, beta 2-blocker therapy?
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Random Allocation; Timolol; Tonometry, Ocular | 1989 |
Efficacy and safety of the combination therapy Pilogel/beta-blocker: interim results.
Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Pilocarpine; Pupil; Refraction, Ocular; Timolol | 1989 |
Effects of D-timolol on intraocular pressure (IOP), beta blocking activity, and the dynamic changes of drug concentrations in aqueous humor.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Animals; Aqueous Humor; Female; Glaucoma; Humans; Hypotension; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Rabbits; Timolol | 1989 |
Efficacy and safety of once-daily levobunolol for glaucoma therapy.
Topics: Administration, Topical; Adult; Aged; Blood Pressure; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Time Factors; Timolol; Tonometry, Ocular | 1989 |
The effect of betablockers with and without ISA on tonographic outflow facility.
Topics: Aqueous Humor; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Pindolol; Random Allocation; Timolol; Tonometry, Ocular | 1989 |
Levobunolol. A four-year study of efficacy and safety in glaucoma treatment. The Levobunolol Study Group.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Longitudinal Studies; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Random Allocation; Time Factors; Timolol; Visual Fields | 1989 |
A long-term clinical trial of timolol therapy versus no treatment in the management of glaucoma suspects.
Topics: Clinical Trials as Topic; Female; Follow-Up Studies; Glaucoma; Humans; Longitudinal Studies; Male; Middle Aged; Multivariate Analysis; Ocular Hypertension; Prospective Studies; Random Allocation; Seasons; Timolol | 1989 |
Long-term evaluation of timolol.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol | 1989 |
"Outlier" intraocular pressure readings: valid or invalid for statistical analysis?
Topics: Analysis of Variance; Clinical Trials as Topic; Clonidine; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Random Allocation; Timolol | 1989 |
The time-course of intraocular pressure in timolol-treated and untreated glaucoma suspects.
Topics: Drug Evaluation; Follow-Up Studies; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Random Allocation; Time Factors; Timolol | 1989 |
Reversibility by timolol of optic nerve disc cupping and pallor in ocular hypertensives.
Topics: Bradycardia; Heart Rate; Humans; Intraocular Pressure; Ocular Hypertension; Optic Disk; Time Factors; Timolol; Visual Fields | 1989 |
Topical timolol administration reduces the incidence of glaucomatous damage in ocular hypertensive individuals. A randomized, double-masked, long-term clinical trial.
Topics: Administration, Topical; Blood Pressure; Glaucoma; Humans; Ocular Hypertension; Optic Disk; Pulse; Timolol; Visual Fields | 1989 |
Treatment of elevated intraocular pressure with concurrent levobunolol and pilocarpine.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Levobunolol; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Timolol | 1987 |
Celiprolol versus timolol and placebo: a two week double-blind comparison.
Topics: Adrenergic beta-Antagonists; Celiprolol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Propanolamines; Pulse; Random Allocation; Timolol | 1987 |
[Comparative study of levobunolol and timolol in the treatment of chronic open-angle glaucoma and chronic ocular hypertension].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Time Factors; Timolol | 1988 |
[Comparison of the effectiveness and safety of levobunolol and timolol in ocular hypertension and chronic open-angle glaucoma].
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Timolol | 1988 |
The effect of long-term intraocular pressure reduction on the differential light sensitivity in glaucoma suspects.
Topics: Humans; Intraocular Pressure; Light; Ocular Hypertension; Regression Analysis; Time Factors; Timolol | 1988 |
The consensual ophthalmotonic reaction.
Topics: Adult; Aged; Aged, 80 and over; Epinephrine; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Time Factors; Timolol | 1988 |
Sympathetic influences on the consensual ophthalmotonic reaction.
Topics: Aged; Female; Guanethidine; Horner Syndrome; Humans; Intraocular Pressure; Male; Middle Aged; Neurons, Efferent; Ocular Hypertension; Reflex; Sympathetic Nervous System; Time Factors; Timolol | 1988 |
A double-masked comparison of carteolol and timolol in ocular hypertension.
Topics: Administration, Topical; Ambulatory Care; Carteolol; Clinical Trials as Topic; Drug Administration Schedule; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Propanolamines; Timolol | 1988 |
Effect of changing medication regimens in glaucoma patients.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Patient Compliance; Timolol | 1988 |
Long-term evaluation of 0.25% levobunolol and timolol for therapy for elevated intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Timolol | 1988 |
Use of an angiotensin converting enzyme inhibitor in ocular hypertension and primary open-angle glaucoma.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Phenylbutyrates; Pulse; Spiro Compounds; Time Factors; Timolol | 1988 |
A study of the effects of four concentrations of D-timolol, 0.25% L-timolol, and placebo on intraocular pressure on patients with raised intraocular pressure.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Middle Aged; Ocular Hypertension; Random Allocation; Stereoisomerism; Timolol | 1988 |
Efficacy of twice-daily levobunolol in the treatment of elevated intraocular pressure.
Topics: Aged; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Timolol | 1988 |
Timolol/pilocarpine combination eye drops in open angle glaucoma and in ocular hypertension. A controlled randomized study.
Topics: Aged; Clinical Trials as Topic; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Random Allocation; Timolol | 1987 |
Glaucoma treatment with once-daily levobunolol.
Topics: Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Levobunolol; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1986 |
Levobunolol compared with timolol for the control of elevated intraocular pressure.
Topics: Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Ocular Hypertension; Timolol | 1986 |
Intraocular pressure changes after neodymium-YAG laser capsulotomy in eyes pretreated with timolol.
Topics: Humans; Laser Therapy; Lens Capsule, Crystalline; Lens, Crystalline; Ocular Hypertension; Pilocarpine; Postoperative Complications; Premedication; Prospective Studies; Timolol | 1987 |
[Tolerance and pharmacologic effectiveness of antiglaucoma eyedrops].
Topics: Adult; Aged; Carteolol; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Propanolamines; Timolol | 1986 |
Levobunolol vs timolol for open-angle glaucoma and ocular hypertension.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Timolol | 1985 |
Levobunolol compared with timolol for the long-term control of elevated intraocular pressure.
Topics: Adult; Aged; Blood Pressure; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Timolol | 1985 |
Long-term ocular hypotensive effect of levobunolol: results of a one-year study.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Time Factors; Timolol | 1985 |
Timolol: long-term Canadian multicentre study.
Topics: Blood Pressure; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Pulse; Timolol | 1985 |
159 other study(ies) available for timolol and Ocular Hypertension
Article | Year |
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Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Glaucoma; Guanidines; In Vitro Techniques; Intraocular Pressure; Lim Kinases; Mice; Nitriles; Ocular Hypertension; Piperazines; Pyrimidines; Pyrroles; Structure-Activity Relationship; Swine; Urea | 2009 |
New furoxan derivatives for the treatment of ocular hypertension.
Topics: Animals; Antihypertensive Agents; Disease Models, Animal; Glaucoma; Intraocular Pressure; Nitric Oxide; Ocular Hypertension; Oxadiazoles; Rabbits; Solubility; Timolol | 2017 |
Treatment of open-angle glaucoma and ocular hypertension with preservative-free tafluprost/timolol fixed-dose combination therapy: 6 case reports and clinical outcomes.
Topics: Aged; Antihypertensive Agents; Glaucoma, Open-Angle; Humans; Middle Aged; Ocular Hypertension; Prostaglandins F; Timolol | 2022 |
Switching to Preservative-Free Tafluprost/Timolol Fixed-Dose Combination in the Treatment of Open-Angle Glaucoma or Ocular Hypertension: Subanalysis of Data from the VISIONARY Study According to Baseline Monotherapy Treatment.
Topics: Adult; Antihypertensive Agents; Bimatoprost; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prospective Studies; Prostaglandins A; Prostaglandins F; Timolol; Travoprost | 2022 |
A comparison of country-level data from the VISIONARY study examining treatment outcomes with preservative-free tafluprost/timolol fixed-dose combination therapy.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Drug Combinations; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins A; Prostaglandins F; Timolol; Treatment Outcome | 2022 |
[Fixed combination of latanoprost and timolol in the long-term treatment of patients with normal-tension glaucoma].
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Low Tension Glaucoma; Ocular Hypertension; Prostaglandins F, Synthetic; Quality of Life; Timolol; Treatment Outcome | 2022 |
Reviewing the evidence surrounding preservative-free tafluprost/timolol fixed-dose combination therapy in open-angle glaucoma and ocular hypertension management: a focus on efficacy, safety, and tolerability.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Timolol | 2022 |
[Efficacy and safety of a fixed combination drug Brinzolol Duo in the treatment of patients with primary open-angle glaucoma].
Topics: Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Timolol; Treatment Outcome | 2022 |
A triple crosslinked micelle-hydrogel lacrimal implant for localized and prolonged therapy of glaucoma.
Topics: Animals; Antihypertensive Agents; Glaucoma; Hydrogels; Intraocular Pressure; Lacrimal Apparatus; Latanoprost; Micelles; Ocular Hypertension; Prostaglandins F, Synthetic; Quality of Life; Rabbits; Timolol; Treatment Outcome | 2023 |
Additive effects of brimonidine tartrate 0.1%/brinzolamide 1% fixed-dose combination in prostaglandin analog-treated Japanese glaucoma patients.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; East Asian People; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Prostaglandins, Synthetic; Timolol | 2023 |
Efficacy of preserved Tafluprost 0.0015% in lowering intraocular pressure.
Topics: Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prostaglandins F; Retrospective Studies; Timolol; Treatment Outcome | 2023 |
Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: The VISIONARY Study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins F; Prostaglandins, Synthetic; Timolol; Tonometry, Ocular | 2020 |
[Effectiveness of antihypertensive conservative-free therapy with fixed combination of bimatoprost and timolol (intermediate results)].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Timolol; Treatment Outcome | 2020 |
European real-world data about the use of a new delivery system containing a preservative-free multi-dose glaucoma treatment.
Topics: Adult; Antihypertensive Agents; Child; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Treatment Outcome | 2021 |
Persistence and treatment patterns of fixed combination drugs for glaucoma: a retrospective claims database study in Japan.
Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Databases, Factual; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Japan; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Prostaglandins, Synthetic; Retrospective Studies; Timolol; Universal Health Insurance | 2020 |
Topical timolol for the treatment of conjunctival pyogenic granulomas: Outcomes and effect on intraocular pressure.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Granuloma, Pyogenic; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Tonometry, Ocular | 2020 |
Comparative evaluation of Latanoprostene Bunod, Timolol Maleate, and latanoprost Ophthalmic Solutions to assess their safety and efficacy in lowering intraocular pressure for the management of Open-Angle Glaucoma.
Topics: Antihypertensive Agents; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2020 |
Efficacy and safety of fixed-combination brimonidine tartrate/timolol maleate in primary open-angle glaucoma, including normal-tension glaucoma.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Timolol; Treatment Outcome | 2021 |
Netarsudil-related Eyelid Wound Dehiscence.
Topics: Aged, 80 and over; Antihypertensive Agents; Benzoates; beta-Alanine; Eyelids; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Timolol | 2021 |
Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: UK and Ireland Results from the VISIONARY Study.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ireland; Ocular Hypertension; Prospective Studies; Prostaglandins F; Timolol; United Kingdom | 2021 |
Long term safety and tolerability of Tafluprost 0.0015% vs Timolol 0.1% preservative-free in ocular hypertensive and in primary open-angle glaucoma patients: a cross sectional study.
Topics: Aged; Antihypertensive Agents; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Tolerance; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Microscopy, Confocal; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Tears; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Pure Glaucoma Drugs Are Toxic to Immortalized Human Corneal Epithelial Cells, but They Do Not Destabilize Lipid Membranes.
Topics: Antihypertensive Agents; Apoptosis; Brimonidine Tartrate; Cell Line; Cell Membrane; Cell Survival; Electrophoresis, Capillary; Epithelium, Corneal; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Liposomes; Membrane Lipids; Ocular Hypertension; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol | 2017 |
Eye Drop Dispenser Type and Medication Possession Ratio in Patients With Glaucoma: Single-Use Containers Versus Multiple-Use Bottles.
Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Drug Combinations; Drug Packaging; Drug Utilization; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
Peyronie's disease and Dupuytren's contracture secondary to topical timolol.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Dupuytren Contracture; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Penile Induration; Timolol | 2019 |
Hypertensive acute granulomatous anterior uveitis as a side effect of topical brimonidine.
Topics: Acute Disease; Adrenergic alpha-2 Receptor Agonists; Aged, 80 and over; Brimonidine Tartrate; Conjunctivitis, Allergic; Cyclopentolate; Drug Therapy, Combination; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Granuloma; Humans; Latanoprost; Lubricant Eye Drops; Ocular Hypertension; Ophthalmic Solutions; Prednisolone; Sulfonamides; Thiophenes; Timolol; Uveitis, Anterior | 2018 |
Is the Use of Refrigerated Fixed Combination of Dorzolamide 2%-Timolol 0.5% (COSOPT) Associated with Less Ocular Discomfort: A Pilot Study.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
[Initial combination therapy for primary open-angle glaucoma].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2019 |
Effect of Dorzolamide/Timolol or Brinzolamide/Timolol prophylaxis on intravitreal anti-VEGF injection-induced intraocular hypertension.
Topics: Administration, Topical; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Vascular Endothelial Growth Factor A | 2013 |
Activity of crude cold-water extract of the culinary-medicinal oyster mushroom, Pleurotus ostreatus (Jacq.:Fr.) P.Kumm. (higher Basidiomycetes), and timolol maleate on induced ocular hypertension.
Topics: Adrenergic beta-Antagonists; Animals; Cold Temperature; Dexamethasone; Glucocorticoids; Mice; Ocular Hypertension; Pleurotus; Random Allocation; Timolol; Water | 2012 |
Comment on "Effect of dacryocystorhinostomy on systemic adverse effects of topical timolol maleate".
Topics: Adrenergic beta-Antagonists; Dacryocystorhinostomy; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Timolol | 2013 |
Urrets- Zavalia Syndrome after glaucoma filtration device implantation.
Topics: Acetazolamide; Aged; Brimonidine Tartrate; Cataract Extraction; Combined Modality Therapy; Drug Resistance; Drug Therapy, Combination; Female; Glaucoma Drainage Implants; Glaucoma, Open-Angle; Humans; Hypertension; Miotics; Mydriasis; Ocular Hypertension; Pilocarpine; Prostaglandins F; Quinoxalines; Sulfonamides; Syndrome; Thiophenes; Timolol | 2013 |
[Signs and symptoms of ocular surface disease in patients on topical intraocular pressure-lowering therapy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blepharitis; Cornea; Cross-Sectional Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Keratitis; Lacrimal Apparatus Diseases; Male; Microscopy, Acoustic; Middle Aged; Ocular Hypertension; Severity of Illness Index; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Young Adult | 2013 |
Early and frequent development of ocular hypertension in children with nephrotic syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Antihypertensive Agents; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Intraocular Pressure; Latanoprost; Male; Nephrotic Syndrome; Ocular Hypertension; Ophthalmic Solutions; Prednisolone; Prevalence; Prostaglandins F, Synthetic; Recurrence; Retrospective Studies; Timolol | 2014 |
Perioperative dorzolamide-timolol intervention for rising intraocular pressure during steep Trendelenburg positioned surgery.
Topics: Adult; Aged; Anesthesia; Antihypertensive Agents; Blindness; Drug Combinations; Female; Head-Down Tilt; Humans; Laparoscopy; Male; Middle Aged; New England; Ocular Hypertension; Ophthalmic Solutions; Perioperative Care; Postoperative Complications; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2014 |
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol | 2015 |
Correcting timolol prescribing in glaucoma management.
Topics: Antihypertensive Agents; Female; Humans; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Timolol | 2015 |
Author's Replay: Correcting timolol prescribing in glaucoma management.
Topics: Antihypertensive Agents; Female; Humans; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Timolol | 2015 |
A biodegradable ocular implant for long-term suppression of intraocular pressure.
Topics: Absorbable Implants; Animals; Antihypertensive Agents; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Intraocular Pressure; Macaca fascicularis; Ocular Hypertension; Polymers; Timolol | 2015 |
Benefits of Tafluprost and Timolol Fixed-Dose Combination for the Treatment of Glaucoma Are Confirmed by Studies on Experimental Animal Models.
Topics: Administration, Ophthalmic; Animals; Antihypertensive Agents; Aqueous Humor; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Male; Ocular Hypertension; Prostaglandins F; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Timolol | 2015 |
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.
Topics: Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Evaluation of Efficacy and Safety of Latanoprost/Timolol versus Travoprost/Timolol Fixed Combinations for Ocular Hypertension Associated with Uveitis.
Topics: Antihypertensive Agents; Drug Combinations; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Retrospective Studies; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Uveitis | 2017 |
Advantages of Efficacy and Safety of Fixed-Dose Tafluprost/Timolol Combination Over Fixed-Dose Latanoprost/Timolol Combination.
Topics: Animals; Antihypertensive Agents; Area Under Curve; Cell Line; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Macaca fascicularis; Male; Metabolic Clearance Rate; Ocular Hypertension; Prostaglandins F; Prostaglandins F, Synthetic; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Time Factors; Timolol; Treatment Outcome | 2016 |
Bioadhesive chitosan-loaded liposomes: A more efficient and higher permeable ocular delivery platform for timolol maleate.
Topics: Animals; Antihypertensive Agents; Chitosan; Drug Evaluation, Preclinical; Drug Liberation; Intraocular Pressure; Liposomes; Male; Ocular Hypertension; Particle Size; Permeability; Rabbits; Timolol; Tissue Distribution | 2017 |
Effect of prophylactic topical hypotensive medications in reducing the incidence of postoperative ocular hypertension after phacoemulsification in dogs.
Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Female; Incidence; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Pre-Exposure Prophylaxis; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2017 |
Recurrent serous macular detachment after topical ocular hypotensive medication.
Topics: Administration, Topical; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Recurrence; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity | 2008 |
Ocular pharmacokinetic/pharmacodynamic modeling for multiple anti-glaucoma drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Algorithms; Animals; Aqueous Humor; Drug Combinations; Glaucoma; Intraocular Pressure; Male; Models, Statistical; Ocular Hypertension; Ophthalmic Solutions; Quinazolines; Rabbits; Telemetry; Timolol | 2008 |
Performing meta-analysis with incomplete statistical information in clinical trials.
Topics: Antihypertensive Agents; Cholesterol, LDL; Clinical Trials as Topic; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Intraocular Pressure; Latanoprost; Meta-Analysis as Topic; Metformin; Ocular Hypertension; Prostaglandins F, Synthetic; Sampling Studies; Sulfonylurea Compounds; Thiazolidinediones; Time Factors; Timolol | 2008 |
Intraocular pressure lowering, change of antiapoptotic molecule expression, and neuroretinal changes by dorzolamide 2%/timolol 0.5% combination in a chronic ocular hypertension rat model.
Topics: Animals; bcl-X Protein; Cell Survival; Disease Models, Animal; Drug Combinations; Glial Fibrillary Acidic Protein; Intraocular Pressure; Male; Ocular Hypertension; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; RNA, Messenger; Sulfonamides; Thiophenes; Timolol | 2008 |
Cost effectiveness of travoprost versus a fixed combination of latanoprost/timolol in patients with ocular hypertension or glaucoma: analysis based on the UK general practitioner research database.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Cost-Benefit Analysis; Databases, Factual; Drug Combinations; Female; Glaucoma; Humans; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Physicians, Family; Prostaglandins F, Synthetic; Timolol; Travoprost; United Kingdom | 2009 |
An in vivo confocal microscopy analysis of effects of topical antiglaucoma therapy with preservative on corneal innervation and morphology.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzalkonium Compounds; Cell Count; Cornea; Drug Combinations; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Microscopy, Confocal; Middle Aged; Ocular Hypertension; Ophthalmic Nerve; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Retrospective Studies; Timolol | 2009 |
Efficacy, tolerability and safety of the fixed combination of bimatoprost 0.03% and timolol 0.5% in a broad patient population: multicenter, open-label observational study.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Optic Disk; Timolol; Visual Fields | 2009 |
Relationship between visual field severity and response to fixed combination dorzolamide/timolol or timolol alone.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Linear Models; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2009 |
Brinzolamide/timolol: in open-angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiazines; Timolol | 2009 |
Intraocular pressure-lowering activity of topical application of Aegle marmelos fruit extract in experimental animal models.
Topics: Administration, Topical; Aegle; Animals; Antihypertensive Agents; Disease Models, Animal; Fruit; Glaucoma; Intraocular Pressure; Ocular Hypertension; Phytotherapy; Plant Extracts; Rabbits; Timolol; Tonometry, Ocular | 2009 |
Corneal thickness and glaucoma medications.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cornea; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Relative efficacy of prostaglandins.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Experimental model of ocular hypertension in the rat: study of the optic nerve capillaries and action of hypotensive drugs.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Capillaries; Disease Models, Animal; Glucose Transporter Type 1; Immunoenzyme Techniques; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Optic Disk; Optic Nerve; Prostaglandins F, Synthetic; Rats; Rats, Wistar; Timolol | 2010 |
Efficacy of tetrandrine on lowering intraocular pressure in animal model with ocular hypertension.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Intraocular Pressure; Male; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Timolol; Tonometry, Ocular; Treatment Outcome | 2011 |
Latanoprost versus timolol as first choice therapy in patients with ocular hypertension. A cost-effectiveness analysis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antihypertensive Agents; Blindness; Cost-Benefit Analysis; Decision Trees; Drug Costs; Female; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Theoretical; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 2012 |
Long-term effect of latanoprost/timolol fixed combination in patients with glaucoma or ocular hypertension: a prospective, observational, noninterventional study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Time Factors; Timolol; Treatment Outcome; Visual Fields; Young Adult | 2010 |
Effectiveness of dorzolamide–timolol (COSOPT) in patients who were treatment naive for open-angle glaucoma or ocular hypertension: the COSOPT first-line study.
Topics: Aged; Drug Combinations; Eye; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
Association of CYP2D6 single-nucleotide polymorphism with response to ophthalmic timolol in primary open-angle Glaucoma--a pilot study.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Bradycardia; Cytochrome P-450 CYP2D6; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Polymorphism, Single Nucleotide; Timolol | 2010 |
The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension.
Topics: Adult; Antihypertensive Agents; Blindness; Brimonidine Tartrate; Decision Trees; Disease Progression; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Biological; Monte Carlo Method; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol | 2011 |
Bimatoprost and bimatoprost/timolol fixed combination in patients with open-angle glaucoma and ocular hypertension.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Drug Combinations; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Timolol; Treatment Outcome | 2011 |
Persistence of glaucoma medical therapy in the Glasgow Glaucoma Database.
Topics: Algorithms; Antihypertensive Agents; Betaxolol; Brimonidine Tartrate; Clinical Protocols; Databases, Factual; Drug Utilization; Female; Glaucoma; Humans; Male; Ocular Hypertension; Quinoxalines; Scotland; Timolol | 2011 |
In vitro comparative toxicology of polyquad-preserved and benzalkonium chloride-preserved travoprost/timolol fixed combination and latanoprost/timolol fixed combination.
Topics: Apoptosis; Benzalkonium Compounds; Cell Line; Cell Survival; Chemistry, Pharmaceutical; Clone Cells; Cloprostenol; Conjunctiva; Drug Combinations; Epithelial Cells; Humans; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Oxidative Stress; Polymers; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Superoxides; Sympatholytics; Timolol; Travoprost | 2011 |
Polyquad-preserved travoprost/timolol, benzalkonium chloride (BAK)-preserved travoprost/timolol, and latanoprost/timolol in fixed combinations: a rabbit ocular surface study.
Topics: Animals; Anti-Bacterial Agents; Antihypertensive Agents; Benzalkonium Compounds; Cell Survival; Cloprostenol; Conjunctiva; Disease Models, Animal; Drug Combinations; Epithelium, Corneal; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Polymers; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Rabbits; Timolol; Travoprost; Treatment Outcome | 2011 |
Asymmetry of 24-hour intraocular pressure reduction by topical ocular hypotensive medications in fellow eyes.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost | 2011 |
Long-term outcomes of prostaglandin analog versus timolol maleate in ocular hypertensive or primary open-angle glaucoma patients in Europe.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Disease Progression; Drug Costs; Europe; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Time Factors; Timolol; Travoprost; Treatment Outcome | 2011 |
Drop size: an issue wrapped in a non-issue wrapped in an issue.
Topics: Adrenergic beta-Antagonists; Humans; Mydriatics; Ocular Hypertension; Ophthalmic Solutions; Phenylephrine; Self Administration; Timolol; United States; United States Food and Drug Administration | 2011 |
Safety and efficacy of monotherapy change to fixed combination (travoprost 0.004%/timolol 0.5%) in 6 months follow up period.
Topics: Antihypertensive Agents; Cloprostenol; Drug Combinations; Drug Substitution; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Timolol; Travoprost | 2010 |
Efficacy and safety of switching to travoprost/timolol fixed-combination therapy from latanoprost monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cloprostenol; Drug Combinations; Drug Substitution; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Surveys and Questionnaires; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Young Adult | 2012 |
Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for glaucoma.
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Feasibility Studies; Intraocular Pressure; Latanoprost; Mice; Mice, Inbred C57BL; Microspheres; Muscarinic Agonists; Ocular Hypertension; Optic Nerve; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Retinal Ganglion Cells; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence | 2012 |
Comparison of tropical travoprost eye drops given once daily and timolol 0.5% given twice daily in patients with open-angle glaucoma or ocular hypertension. J. Glaucoma 2001;10:414-22.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost | 2002 |
Identification and characterization of the ocular hypotensive efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist, and AL-6598, a DP prostaglandin receptor agonist.
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Cats; Cloprostenol; Dinoprost; Dose-Response Relationship, Drug; Female; Glaucoma, Open-Angle; Guinea Pigs; Humans; Intraocular Pressure; Macaca fascicularis; Male; Ocular Hypertension; Rabbits; Randomized Controlled Trials as Topic; Receptors, Immunologic; Receptors, Prostaglandin; Safety; Structure-Activity Relationship; Timolol; Travoprost | 2002 |
Choroidal detachment induced by dorzolamide 20 years after cataract surgery.
Topics: Aged; Antihypertensive Agents; Cataract Extraction; Choroid Diseases; Drug Therapy, Combination; Female; Humans; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
Experience with Cosopt, the fixed combination of timolol and dorzolamide, after switch from free combination of timolol and dorzolamide, in Swiss ophthalmologists' offices.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cluster Analysis; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Ophthalmology; Sulfonamides; Switzerland; Thiophenes; Timolol | 2003 |
Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Pulsatile Flow; Regional Blood Flow; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2004 |
Brimonidine and latanoprost as adjunctive therapy.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2004 |
Bimatoprost versus timolol and dorzolamide.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Lipids; Ocular Hypertension; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2005 |
The effect of combination pharmacotherapy on the prescription trends of glaucoma medications.
Topics: Antihypertensive Agents; Drug Combinations; Drug Prescriptions; Drug Utilization; Glaucoma, Open-Angle; Health Maintenance Organizations; Health Services Research; Health Surveys; Humans; Intraocular Pressure; Israel; Ocular Hypertension; Practice Patterns, Physicians'; Sulfonamides; Thiophenes; Timolol | 2005 |
How to control measurement variation in estimating the mean intraocular pressure reducing effect at a specific point in time.
Topics: Antihypertensive Agents; Functional Laterality; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Models, Statistical; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Research Design; Sample Size; Time Factors; Timolol; Tonometry, Ocular | 2005 |
Modern alchemy: fixed combinations of glaucoma drugs.
Topics: Antihypertensive Agents; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost; Treatment Outcome | 2005 |
Effects of a non-selective beta-blocker on adult rat anterograde axonal transport and retinal ganglion layer after increased intraocular pressure.
Topics: Adrenergic beta-Antagonists; Animals; Axonal Transport; Disease Models, Animal; Glaucoma; Intraocular Pressure; Male; Ocular Hypertension; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; Timolol | 2005 |
Physicochemical properties and in vivo assessment of timolol-loaded poly(D,L-lactide-co-glycolide) films for long-term intraocular pressure lowering effects.
Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Delivery Systems; Intraocular Pressure; Male; Ocular Hypertension; Polyglactin 910; Rabbits; Solubility; Surface Properties; Tensile Strength; Time Factors; Timolol; Treatment Outcome | 2005 |
Does timolol LA enhance the disrupting effect of travoprost on the blood-aqueous barrier?
Topics: Adult; Antihypertensive Agents; Blood-Aqueous Barrier; Cloprostenol; Drug Synergism; Drug Therapy, Combination; Gonioscopy; Humans; Intraocular Pressure; Male; Ocular Hypertension; Timolol; Travoprost; Uveitis, Anterior | 2006 |
In vivo confocal microscopic findings of interlamellar stromal keratopathy induced by elevated intraocular pressure.
Topics: Acetazolamide; Adult; Antihypertensive Agents; Corneal Diseases; Corneal Stroma; Drug Therapy, Combination; Glucocorticoids; Humans; Intraocular Pressure; Keratomileusis, Laser In Situ; Male; Microscopy, Confocal; Ocular Hypertension; Postoperative Complications; Prednisolone; Timolol; Visual Acuity | 2006 |
Brimonidine/Timolol: a viewpoint by Francisco J. Goñi.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
Reduced ocular allergy with fixed-combination 0.2% brimonidine-0.5% timolol.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Conjunctivitis, Allergic; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Timolol | 2007 |
Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Benzoxazines; Blood Pressure; Calcium Channel Blockers; Camphanes; Heart Rate; Intraocular Pressure; Irritants; Male; Morpholines; Naphthalenes; Ocular Hypertension; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Timolol | 2008 |
R-enantiomer of timolol: a potential selective ocular antihypertensive agent.
Topics: Animals; Aqueous Humor; Binding Sites; Bronchi; Chymotrypsin; Ciliary Body; Dihydroalprenolol; Dose-Response Relationship, Drug; Female; Glaucoma; Guinea Pigs; Humans; Intraocular Pressure; Iris; Male; Ocular Hypertension; Rabbits; Receptors, Adrenergic, beta; Time Factors; Timolol; Trachea | 1984 |
[Effect of beta-adrenoblockers on prostaglandin-induced ocular hypertension in rabbits].
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Dinoprostone; Male; Ocular Hypertension; Oxprenolol; Propanolamines; Propranolol; Prostaglandins E; Rabbits; Timolol | 1983 |
Treatment of ocular hypertension and glaucoma with dopamine antagonists.
Topics: Animals; Antipsychotic Agents; Butyrophenones; Dopamine Antagonists; Female; Glaucoma; Guinea Pigs; Haloperidol; Histamine Antagonists; Intraocular Pressure; Male; Muscle Relaxation; Myocardial Contraction; Ocular Hypertension; Rabbits; Timolol; Trifluperidol | 1984 |
[Residual effect of timoptol in ocular hypertension].
Topics: Aged; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Time Factors; Timolol | 1983 |
[Objective attempt at an estimation of the long-term efficacy of Timolol (15 months). Study of 73 patients].
Topics: Follow-Up Studies; Glaucoma; Humans; Ocular Hypertension; Timolol | 1983 |
Experience with dipivalyl epinephrine. Its effectiveness, alone or in combination, and its side effects.
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma; Glaucoma, Open-Angle; Headache; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1983 |
Timolol: a 4-year follow-up study.
Topics: Adult; Aged; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Timolol | 1983 |
Timolol and postoperative intraocular pressure.
Topics: Cataract Extraction; Humans; Intraocular Pressure; Lenses, Intraocular; Ocular Hypertension; Postoperative Care; Postoperative Complications; Timolol | 1984 |
The effect of d-timolol on intraocular pressure in patients with ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Evaluation; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pupil; Random Allocation; Stereoisomerism; Timolol; Visual Acuity | 1984 |
Vascular effects of timolol and pilocarpine in the iris. A simultaneous bilateral fluorescein angiographic study.
Topics: Adult; Aged; Female; Fluorescein Angiography; Glaucoma; Humans; Iris; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Propanolamines; Timolol | 1983 |
Timolol treatment of chronic open-angle glaucoma and ocular hypertension. A 2.5-year multicenter study.
Topics: Adult; Aged; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; Ocular Hypertension; Propanolamines; Timolol; Visual Fields | 1982 |
Timolol for treatment of glaucoma. (One year follow up).
Topics: Cataract; Glaucoma; Glaucoma, Open-Angle; Humans; Ocular Hypertension; Propanolamines; Timolol | 1982 |
Timolol and dipivalyl epinephrine combination therapy.
Topics: Aged; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Propanolamines; Timolol | 1982 |
Effect of timolol with and without preservative on the basal tear turnover in glaucoma.
Topics: Benzalkonium Compounds; Fluorophotometry; Glaucoma, Open-Angle; Humans; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Secretory Rate; Tears; Timolol | 1995 |
The effect of treatment on the results of high-pass resolution perimetry in glaucoma.
Topics: Aged; Betaxolol; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Retrospective Studies; Sensory Thresholds; Timolol; Visual Field Tests; Visual Fields; Visual Perception | 1994 |
Topical timolol, corneal epithelial permeability and autofluorescence in glaucoma by fluorophotometry.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cell Membrane Permeability; Cornea; Epithelium; Fluorescence; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1994 |
Topical timolol with and without benzalkonium chloride: epithelial permeability and autofluorescence of the cornea in glaucoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Benzalkonium Compounds; Cell Membrane Permeability; Cornea; Epithelium; Fluorophotometry; Glaucoma, Open-Angle; Humans; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1994 |
Visual field prognosis in early glaucoma. A long-term clinical follow-up.
Topics: Acetazolamide; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Ocular Hypertension; Optic Nerve Diseases; Pilocarpine; Prognosis; Retrospective Studies; Risk Factors; Timolol; Vision Disorders; Visual Fields | 1993 |
Can the concentration of timolol or the frequency of its administration be reduced?
Topics: Adult; Aged; Circadian Rhythm; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol | 1993 |
Preliminary evaluation of a series of amphiphilic timolol prodrugs: possible evidence for transscleral absorption.
Topics: Absorption; Animals; Cell Membrane Permeability; Cornea; Disease Models, Animal; Esters; Evaluation Studies as Topic; Intraocular Pressure; Isoproterenol; Ocular Hypertension; Pilot Projects; Prodrugs; Rabbits; Sclera; Solubility; Timolol | 1993 |
Pattern electroretinogram in treated ocular hypertension: a cross-sectional study after timolol maleate therapy.
Topics: Adult; Aged; Antihypertensive Agents; Cross-Sectional Studies; Electroretinography; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pattern Recognition, Visual; Retina; Timolol | 1995 |
Intraocular pressure after a two-week washout following long-term timolol or levobunolol.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Tonometry, Ocular | 1995 |
Vaninolol: a novel compound for the treatment of glaucoma and ischemic retinopathy.
Topics: Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Butanones; Electroretinography; Eye; Female; Glaucoma; Intraocular Pressure; Ischemia; Male; Microspheres; Ocular Hypertension; Propanolamines; Rabbits; Rats; Retina; Retinal Artery; Retinal Artery Occlusion; Timolol | 1995 |
Measurement of intraocular pressure by telemetry in conscious, unrestrained rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Circadian Rhythm; Consciousness; Female; Glucose; Heart Rate; Intraocular Pressure; Motor Activity; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Reproducibility of Results; Restraint, Physical; Telemetry; Timolol; Tonometry, Ocular | 1996 |
[A new type of headache of ocular origin: ophthalmotonic headache. Diagnosis and treatment].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Female; Headache; Humans; Laser Therapy; Male; Middle Aged; Ocular Hypertension; Refraction, Ocular; Timolol | 1997 |
Five-year follow-up of treated patients with glaucoma using resolution perimetry.
Topics: Aged; Betaxolol; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Timolol; Treatment Outcome; Visual Acuity; Visual Field Tests; Visual Fields | 1998 |
Pharmacological evaluation of a new timolol/pilocarpine formulation.
Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chymotrypsin; Intraocular Pressure; Muscarinic Agonists; Ocular Hypertension; Pilocarpine; Rabbits; Timolol | 1998 |
Influence of dorzolamide on corneal thickness, endothelial cell count and corneal sensibility.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Cell Count; Chronic Disease; Cornea; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Sensation; Sulfonamides; Thiophenes; Timolol | 1998 |
The safety and efficacy of switching timolol maleate 0.5% solution to timolol hemihydrate 0.5% solution given twice daily.
Topics: Aged; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1998 |
Ocular tension and pupil diameter effects of timolol 0.50% and pilocarpine 2% or 4% in association.
Topics: Adrenergic beta-Antagonists; Aged; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pupil; Timolol; Treatment Outcome | 1997 |
The effect of pneumoperitoneum on intraocular pressure in rabbits with alpha-chymotrypsin-induced glaucoma.
Topics: Adjuvants, Anesthesia; Administration, Topical; Anesthesia, General; Animals; Antihypertensive Agents; Blood Pressure; Body Temperature; Carbon Dioxide; Central Venous Pressure; Chymotrypsin; Disease Models, Animal; Glaucoma; Head-Down Tilt; Heart Rate; Insufflation; Intraocular Pressure; Male; Ocular Hypertension; Pentobarbital; Pneumoperitoneum, Artificial; Posture; Pressure; Rabbits; Reproducibility of Results; Time Factors; Timolol; Tonometry, Ocular | 1998 |
[A long-term study of the visual fields in patients treated with betaxolol and timolol].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Belgium; Betaxolol; Female; Glaucoma; Glaucoma, Angle-Closure; Humans; Male; Middle Aged; Ocular Hypertension; Paris; Switzerland; Time Factors; Timolol; Visual Fields | 1998 |
A comparison of trabeculectomy with topically applied timolol in a rabbit ocular hypertension model.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Female; Fluorocarbons; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Timolol; Trabeculectomy; Treatment Outcome | 1998 |
Prevalence and management of elevated intraocular pressure in patients with Graves' orbitopathy.
Topics: Adult; Aged; Antihypertensive Agents; Decompression, Surgical; Female; Glaucoma, Open-Angle; Graves Disease; Humans; Male; Middle Aged; Miotics; Netherlands; Ocular Hypertension; Optic Disk; Pilocarpine; Prevalence; Retrospective Studies; Timolol; Visual Fields | 1998 |
Aqueous humor dynamics in alpha-chymotrypsin-induced ocular hypertensive rabbits.
Topics: Animals; Aqueous Humor; Chymotrypsin; Eye Proteins; Intraocular Pressure; Ocular Hypertension; Pilocarpine; Rabbits; Timolol; Tonometry, Ocular; Trabecular Meshwork | 1999 |
[Bradycardia of an elderly patient caused by Timolol therapy in ocular hypertension].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Bradycardia; Electrocardiography; Female; Follow-Up Studies; Humans; Ocular Hypertension; Timolol | 1996 |
Long-term topical timolol and blood lipids: the Blue Mountains Eye Study.
Topics: Adrenergic beta-Antagonists; Anticholesteremic Agents; Cholesterol, HDL; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Male; Middle Aged; New South Wales; Ocular Hypertension; Ophthalmic Solutions; Optic Disk; Sex Factors; Time Factors; Timolol; Triglycerides; Urban Population | 2000 |
Effect of SR121463, a selective non-peptide vasopressin V2 receptor antagonist, in a rabbit model of ocular hypertension.
Topics: Administration, Oral; Administration, Topical; Animals; Antidiuretic Hormone Receptor Antagonists; Cell Membrane; Clonidine; Disease Models, Animal; Injections, Intravenous; Intraocular Pressure; Kidney; Male; Morpholines; Ocular Hypertension; Rabbits; Receptors, Vasopressin; Safety; Spiro Compounds; Timolol | 2000 |
Preliminary results of a study of the follow-up of nine glaucomatous patients treated with preservative-free eye drops.
Topics: Adrenergic beta-Antagonists; Follow-Up Studies; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Tears; Timolol | 2000 |
Case reports and small case series: LASIK-associated visual field loss in a glaucoma suspect.
Topics: Cornea; Female; Humans; Intraocular Pressure; Keratomileusis, Laser In Situ; Latanoprost; Middle Aged; Myopia; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Vision Disorders; Visual Acuity; Visual Fields | 2001 |
[Glaucoma related with photoreceptor outer segments in aqueous humor. Schwartz-Matsuo syndrome].
Topics: Adult; Aqueous Humor; Diagnosis, Differential; Diagnostic Errors; Eye Injuries; Glaucoma; Humans; Iritis; Male; Melanins; Methylprednisolone; Myopia; Ocular Hypertension; Recurrence; Retinal Detachment; Rod Cell Outer Segment; Rupture, Spontaneous; Syndrome; Timolol; Trabecular Meshwork; Uveitis | 2001 |
Systemic beta-blocker therapy and brimonidine and timolol.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Brimonidine Tartrate; Clinical Trials as Topic; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol | 2001 |
Timolol increased retrobulbar flow velocities in untreated glaucoma eyes but not in ocular hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Blood Flow Velocity; Blood Pressure; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Artery; Ophthalmic Solutions; Retinal Artery; Timolol; Ultrasonography, Doppler, Color | 2001 |
Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Cell Survival; Chronic Disease; Cytoprotection; Glial Fibrillary Acidic Protein; Intraocular Pressure; Laser Coagulation; Male; Neuroprotective Agents; Ocular Hypertension; Quinoxalines; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; Time Factors; Timolol | 2001 |
Ocular and retrobulbar blood flow in ocular hypertensives treated with topical timolol, betaxolol and carteolol.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Betaxolol; Blood Flow Velocity; Carteolol; Ciliary Arteries; Humans; Middle Aged; Ocular Hypertension; Ophthalmic Artery; Retinal Artery; Timolol | 2001 |
The effect of topical CS-088, an angiotensin AT1 receptor antagonist, on intraocular pressure and aqueous humor dynamics in rabbits.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Aqueous Humor; Chymotrypsin; Disease Models, Animal; Imidazoles; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Timolol | 2001 |
Travoprost compared with latanoprost and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Drug Evaluation; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Timolol; Travoprost | 2002 |
Effect of hyaluronic acid on intraocular pressure in rats.
Topics: Animals; Anterior Chamber; Antihypertensive Agents; Brimonidine Tartrate; Disease Models, Animal; Hyaluronic Acid; Injections; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Timolol; Tonometry, Ocular | 2002 |
An accurate comparison of bimatoprost's efficacy and adverse effects.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Humans; Intraocular Pressure; Lipids; Ocular Hypertension; Safety; Timolol | 2002 |
Long-term drift and timolol therapy: possible role for pulsed therapy.
Topics: Aged; Aged, 80 and over; Drug Administration Schedule; Epinephrine; Humans; Intraocular Pressure; Longitudinal Studies; Middle Aged; Ocular Hypertension; Timolol | 1992 |
Effects of D- and L-isomers of timolol on retinal and choroidal blood flow in ocular hypertensive rabbit eyes.
Topics: Animals; Choroid; Ciliary Body; Disease Models, Animal; Iris; Microspheres; Ocular Hypertension; Rabbits; Regional Blood Flow; Retinal Vessels; Stereoisomerism; Timolol | 1992 |
[The effect of Inj. Salviae Miltiorrhizae Co. on the retrograde axoplasmic transport in the optic nerve of rabbits with chronic IOP elevation].
Topics: Animals; Axonal Transport; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Intraocular Pressure; Male; Ocular Hypertension; Optic Nerve; Plant Extracts; Rabbits; Salvia miltiorrhiza; Timolol | 1991 |
[Modification of tear film break-up time by beta blocker eyedrops without preservatives].
Topics: Glaucoma; Humans; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Tears; Timolol | 1991 |
Treatment trials of glaucoma suspects.
Topics: Humans; Intraocular Pressure; Ocular Hypertension; Randomized Controlled Trials as Topic; Timolol; Visual Fields | 1991 |
The progress of the visual field in chronic simple glaucoma and ocular hypertension treated topically with pilocarpine or with timolol.
Topics: Administration, Topical; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Male; Ocular Hypertension; Pilocarpine; Prospective Studies; Timolol; Visual Fields | 1990 |
Efficacy of adding dipivefrin to a beta-blocker.
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Levobunolol; Ocular Hypertension; Timolol | 1990 |
Flicker sensitivity in treated ocular hypertension.
Topics: Adult; Aged; Contrast Sensitivity; Female; Flicker Fusion; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Visual Fields | 1990 |
Glaucoma suspect treatment trial.
Topics: Humans; Ocular Hypertension; Timolol; Visual Fields | 1990 |
Primary argon laser trabeculoplasty after pretreatment with timolol. A safe and economic therapy of early glaucoma.
Topics: Aged; Aged, 80 and over; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Premedication; Prospective Studies; Timolol; Trabeculectomy | 1990 |
Corneal endothelial changes in ocular hypertensive individuals after long-term unilateral treatment with timolol.
Topics: Aged; Cell Count; Cornea; Endothelium, Corneal; Female; Humans; Male; Middle Aged; Ocular Hypertension; Time Factors; Timolol | 1990 |
[The effect of adrenaline, pilocarpine and timolol on axoplasmic transport in the optic nerve. II. Findings in eyes with increased intraocular pressure].
Topics: Animals; Axonal Transport; Epinephrine; Female; Ocular Hypertension; Optic Nerve; Pilocarpine; Rats; Timolol | 1985 |
Anterior ischemic optic neuropathy and increased intraocular pressure.
Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Ischemia; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Neuritis; Timolol; Visual Acuity | 1989 |
Effect of IOP on the visual field in ocuLar hypertension and glaucoma.
Topics: Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Prognosis; Risk Factors; Timolol; Visual Fields | 1989 |
Allergic contact dermatitis to timolol.
Topics: Blepharitis; Conjunctivitis; Drug Eruptions; Eyelid Diseases; Humans; Male; Middle Aged; Ocular Hypertension; Patch Tests; Timolol | 1986 |
Therapeutic problems in ocular hypertension.
Topics: Drug Therapy, Combination; Epinephrine; Humans; Ocular Hypertension; Pilocarpine; Risk Factors; Timolol | 1988 |
Topical timolol-induced arthropathy.
Topics: Female; Humans; Joint Diseases; Knee Joint; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pain; Timolol | 1988 |
Prevention of intra-ocular pressure elevation following laser surgery.
Topics: Acetazolamide; Drug Therapy, Combination; Humans; Laser Therapy; Ocular Hypertension; Timolol | 1986 |
[An undesirable effect of a beta-blocker].
Topics: Erectile Dysfunction; Humans; Male; Middle Aged; Ocular Hypertension; Timolol | 1987 |
Laser-induced glaucoma in rabbits.
Topics: Animals; Aqueous Humor; Colforsin; Disease Models, Animal; Glaucoma; Lasers; Ocular Hypertension; Optic Disk; Pilocarpine; Rabbits; Timolol; Trabecular Meshwork | 1986 |