timolol has been researched along with Intraocular Pressure in 1458 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 401 (27.50) | 18.7374 |
| 1990's | 297 (20.37) | 18.2507 |
| 2000's | 402 (27.57) | 29.6817 |
| 2010's | 289 (19.82) | 24.3611 |
| 2020's | 69 (4.73) | 2.80 |
| Authors | Studies |
|---|---|
| Antonaroli, S; Bianco, A; Bonomi, L; Brufani, M; Cellai, L; Fiaschi, AI; Lo Baido, G; Perfetti, S; Potier, E; Segre, G | 1 |
| Bodor, N; ElKoussi, A; Kano, M; Nakamura, T | 1 |
| Sugrue, MF | 2 |
| Allen, J; Almstead, ZY; Courtney, LF; Crist, M; Crosson, CE; Gardyan, M; Gopinathan, S; Gu, KJ; Hamman, BD; Harrison, BA; Key, B; Kimball, SD; Liu, Q; Liu, Y; Mabon, R; McKnight, B; Patel, N; Rawlins, DB; Rice, DS; Voronkov, MV; Whitlock, NA; Wilson, AG; Yates, PW; Zhang, Y; Zhou, J | 1 |
| Almirante, N; Bastia, E; Blangetti, M; Chegaev, K; Durante, M; Fruttero, R; Gasco, A; Guglielmo, S; Impagnatiello, F; Lazzarato, L; Masini, E; Rolando, B | 1 |
| Beznos, OV; Chesnokova, NB; Lozinskaya, NA; Volkova, MS; Zaryanova, EV; Zefirov, NS | 1 |
| Andring, JT; Bua, S; Carta, F; Ceruso, M; Filippi, L; Gratteri, P; Lanzi, C; Lomelino, CL; Masini, E; Matucci, R; McKenna, R; Nocentini, A; Pecori, R; Selleri, S; Sgambellone, S; Supuran, CT | 1 |
| Chang, SN; Kuo, BI; Lin, JW; Nishida, T; Wu, JH | 1 |
| Aihara, M; Iwata, A; Kawata, H; Lu, F; Odani-Kawabata, N | 1 |
| Chung, HW; Ji, MJ; Kim, YY; Park, JH; Yoo, C; Yoon, EG | 1 |
| Gupta, N; Hanna, J; Irving, H; Kim, N; Yücel, YH; Zhou, X | 1 |
| Fan, S; Gilbert, J; Gulati, V; Kazemi, A; Kolli, A; Moroi, SE; Musch, DC; Reed, DM; Sit, AJ; Toris, CB | 1 |
| Huang, T; Shen, J; Xiong, X; Yan, J | 1 |
| Bacharach, J; Bejanian, M; Belalcázar, S; Chen, MY; Ferguson, G; Goodkin, ML; Guo, Q; Liu, J; Robinson, MR; Tatham, A; Thieme, H; Wirta, DL | 1 |
| Çakmak, K; Erbil, H; Korkmaz, Ş; Mesci, C | 1 |
| Andreadis, D; Andreadis, II; Bouropoulos, N; Fatouros, DG; Karavasili, C; Komnenou, A; Thomas, A; Tzetzis, D; Tzimtzimis, M | 1 |
| Bartošová, L; Fůs, M; Lešták, J; Marešová, K | 1 |
| Asghari, A; Ozmaie, S; Rajaei, SM; Ziadi, A | 1 |
| Barbosa, GCS; Lima, VL; Mota, RT; Susanna, BN; Susanna, CN; Susanna, FN; Susanna, R | 1 |
| Fassari, C; Holló, G; Kirwan, J; Lopez-Lopez, F; Oddone, F; Zimina, M | 2 |
| Brye, N; Camp, A; Do, JL; El-Nimri, NW; Ghahari, E; Moghimi, S; Penteado, RC; Proudfoot, J; Rubio, V; Salcedo, M; Weinreb, RN; Yang, D | 1 |
| Aapola, U; Nukareddy, P; Uusitalo, H; Välimäki, J | 1 |
| Karlova, EV; Zolotarev, AV | 1 |
| Ahn, HS; Chang, DJ; Chang, J; Kang, HY; Lee, H; Lee, JW; Suh, JK | 1 |
| Oddone, F | 1 |
| Alekseev, IB; Alekseeva, LI; Volkova, AV | 1 |
| Bigdeli, A; Feghhi, M; Makhmalzadeh, BS; SoleimaniBiatiani, E | 1 |
| Bleskina, MY; Kolotilina, NE; Lisitsyn, AB; Loskutov, IA; Poromov, AA | 1 |
| Gou, J; He, H; Long, L; Ning, Y; Tang, X; Wang, Z; Xiong, J; Yin, T; Zhang, Y; Zhao, J | 1 |
| Achiron, A; Goldberg, M; Hayat, H; Masarwa, D | 1 |
| Cenk Celebi, AR; Nur Pilevne, S; Ozdemir, S; Uner, B | 1 |
| Gugleta, K; Hasler, PW; Saruhan, Y | 1 |
| Athanasopoulos, GP; Boboridis, KG; Haidich, AB; Katsanos, A; Katz, LJ; Konstas, AG; Pagkalidou, E; Voudouragkaki, IC | 1 |
| Fujita, A; Kaji, Y; Oshika, T; Palchunova, K | 1 |
| Abe, H; Aoki, R; Arimura, S; Hayashi, K; Inatani, M; Inoue, C; Inoue, K; Inoue, T; Ishida, A; Ishiyama, S; Iwasaki, K; Kagaya, F; Kanamori, A; Kano, K; Kido, N; Kurimoto, T; Kuwamura, R; Kuwayama, Y; Lee, J; Manabe, K; Manabe, S; Matsuyama, A; Mori, S; Murai, Y; Musashi, K; Nakagawa, S; Nakakura, S; Nakamura, M; Oi, J; Orii, Y; Otani, S; Ozaki, M; Sagara, T; Saito, Y; Sakono, T; Sameshima, M; Shiokawa, M; Sunagawa, H; Suzuki, K; Takaki, K; Tanabe, H; Tanito, M; Tsutsui, A; Ueda, K; Urahashi, M; Watanabe-Kitamura, F; Yamada-Nakanishi, Y; Yamashita, T; Yoshida, A | 1 |
| Adachi, M; Aihara, M; Asato, R; Hamada, N; Hara, T; Mizoue, S; Muramatsu, T; Naito, T; Ohkubo, S; Sakata, R; Yoshikawa, K | 1 |
| Paul, C | 1 |
| Moshetova, LK; Soshina, MM; Sychev, DA; Turkina, KI | 1 |
| Eldaly, ZH; Rateb, MF; Soliman, WM | 1 |
| Bachmann, LM; Jensen, BP; Müller, L; Wells, AP; Wong, D | 1 |
| Fang, Y; Gan, D; Jiang, R; Ku, H; Sun, X | 1 |
| Chen, O; Jamieson, MPH; Ling, D; Perera, N; Pinnuck, BC; Williams, M | 1 |
| Del Amo, EM; Fayyaz, A; Gardner, I; Heikkinen, EM; Jamei, M; Ranta, VP; Reinisalo, M; Ricci, GD; Toropainen, E; Urtti, A; Vellonen, KS | 1 |
| Ha, A; Jeoung, JW; Kim, YK; Park, KH; Wy, S | 1 |
| Holló, G; Kóthy, P; Oddone, F; Tanga, L | 1 |
| Belfort, R; Chen, MY; Della Paolera, M; Goodkin, ML; Kim, T; Lopes Silva, MJ; Paula, JS | 1 |
| Huang, S; Xing, Y; Zhang, K; Zhu, L | 1 |
| Ahmed, KA; Al-Sawahli, MM; Alolayan, EM; El-Feky, YA; El-Telbany, DFA; El-Telbany, RFA; Fayez, AM; Mostafa, DA; Zakaria, S | 1 |
| Esfandiari, H; Tanna, AP; Teramoto, K | 1 |
| Chen, E; Chiang, A; Garg, SJ; Ho, AC; Hsu, J; Jenkins, TL; Mikhail, M; Obeid, A; Patel, SN; Shah, CP; Spirn, MJ; Vander, JF; Wibbelsman, TD; Wolfe, JD | 1 |
| Ciganov, AZ; Dorofeev, DA; Kryzhanovskaya, AV | 1 |
| Chen, E; Denis, P; Duch, S; Erb, C; Klyve, P; Puska, P; Skov, J | 1 |
| Desai, AR; Desai, DM; Maulvi, FA; Ranch, KM; Sandeman, S; Shah, DO; Shah, SA; Shukla, MR; Vyas, BA | 1 |
| Arfaee, F; Asghari, A; Khaksar, E; Shokoohimand, A | 1 |
| Chono, E; Kashiwagi, K; Koesters, S; Yap, PS | 1 |
| Bejanian, M; Coote, M; Goodkin, ML; Guo, Q; Kolko, M; Medeiros, FA; Robinson, MR; Walters, TR; Weinreb, RN; Zhang, J | 1 |
| Freddo, TF; Furtado, N; Ho, DY; Steenbakkers, M | 1 |
| Germanova, VN; Karlova, EV; Petrov, SY | 1 |
| Khomyakova, EN; Ryabtseva, AA; Sergushev, SG | 1 |
| Fechtner, RD; Heah, T; Kim, T; Kopczynski, CC; Lewis, RA; McKee, H; Myers, JS; Sheng, H; Singh, IP; Usner, DW | 1 |
| George, RJ; Jain, V; Nair, AG; Natarajan, S | 1 |
| Holló, G; Hutnik, CML; Katsanos, A; Katz, LJ; Konstas, AG; Pfeiffer, N; Quaranta, L; Schmetterer, L; Teus, MA; Uusitalo, H | 1 |
| Dudhipala, N; ElSohly, MA; Gul, W; Majumdar, S; Marathe, S; Mehraj, T; Murphy, B; Sweeney, C; Thakkar, R | 1 |
| Alvarez Igarzabal, CI; Cuggino, JC; Gugliotta, LM; Palma, SD; Tártara, LI | 1 |
| Liao, Y; Nie, X; Wang, Y | 1 |
| Filimonova, EE; Kogan, MP; Pashentsev, YE; Sorokin, EL | 1 |
| Barbeau, M; Beauchemin, C; Cui, AX; Harasymowycz, P; Jobin-Gervais, K; Lachaine, J; Mathurin, K; Royer, C | 1 |
| Armengol, L; Banchs, I; Canut, MI; Casaroli-Marano, RP; González, JR; Kudsieh, B; Mattlin, H; Villa, O | 1 |
| Kim, JM; Lee, JW; Maglambayan, J; Park, KH; Park, SW; Simonyi, S | 1 |
| Dagi Glass, LR; Kim, HM; Tran, AQ; Yang, C | 1 |
| Ansari, E; Ayan, F; King, AJ; Kinsella, M; Ng, E; Nita, A; Pavicic-Astalos, J | 1 |
| Azuara-Blanco, A; Freiberg, J; Kolko, M; Rives, AS; Skov, AG; Virgili, G | 1 |
| Aihara, M; Kishimoto, N; Kizaki, J; Saito, Y; Shibasaki, Y; Wada, Y | 1 |
| Coroneo, M; Huang, J; Kalloniatis, M; Tong, J; Zangerl, B | 1 |
| Huang, J; Ma, F; Pang, Y; Song, Y; Wang, F; Wang, X; Wang, Y; Wu, B; Zhang, W; Zhang, X; Zhu, Z | 1 |
| Adachi, M; Aihara, M; Fukuchi, T; Matsuo, H; Sasaki, N; Togano, T | 1 |
| Akyol, N; Imamoglu, HI; Kalkisim, A; Kola, M; Turk, A | 1 |
| Huang, J; Huang, Y; Li, Y; Pan, X; Peng, T; Wu, C; Wu, CY; Zeng, Y; Zhan, Z | 1 |
| Chen, Y; Feng, X; Gao, C; Li, Y; Qi, H; Wang, M; Zhang, Y | 1 |
| Allemandi, DA; Battistini, FD; Boiero, C; Guzmán, ML; Luciani-Giaccobbe, LC; Manzo, RH; Olivera, ME; Palma, SD; Tártara, LI | 1 |
| Kimura, T; Matsumoto, S; Mizoue, S; Nitta, A; Nitta, K; Shirakashi, M; Takeda, R; Ueda, T; Yamabayashi, S; Yoshikawa, K | 1 |
| Ates, H; Degirmenci, C; Guven Yilmaz, S; Karakoyun, YE; Yusifov, E | 1 |
| Callahan, AB; Nanda, T; Odel, JG; Rasool, N; Stamper, RL | 1 |
| Balsak, S; Erdem, S; Fuat Alakus, M; Kaydu, A; Ozkurt, ZG | 1 |
| Nuzzi, R; Rolle, T; Spinetta, R | 1 |
| Chiboub, O; De Agustino Rodríguez, J; López-Arencibia, A; Lorenzo-Morales, J; Piñero, JE; Reyes-Batlle, M; Rocha-Cabrera, P; Sifaoui, I; Valladares, B; Wagner, C | 1 |
| Holopainen, JM; Pisella, PJ; Rantamäki, AH; Robciuc, A; Ruokonen, SK; Wiedmer, SK; Witos, J | 1 |
| Aljasim, LA; Bradfield, Y; Dixon, ER; Feldman, R; Gustafson, N; Landry, T; Salem, C; Venkataraman, S | 1 |
| Kanai, K; Kawasaki, N; Nagai, N; Nakazawa, Y; Ogata, F; Okamoto, N; Otake, H; Shimomura, Y | 1 |
| Caruso, A; Chiaradia, G; D'Oria, L; De Luca, C; De Santis, M; Licameli, A; Neri, C; Nucci, M; Pellegrino, M; Visconti, D | 1 |
| Lee, TE; Park, YM | 1 |
| Bahler, CK; Bertrand, JA; Dosa, PI; Fautsch, MP; Holman, BH; Millar, JC; Overby, DR; Rinkoski, TA; Roy Chowdhury, U; Sherwood, JM; Stoltz, KL | 1 |
| Allemandi, DA; Arias, FJ; Fernández-Colino, A; Girotti, A; Palma, SD; Quinteros, DA | 1 |
| Belcaro, G; Feragalli, B; Gizzi, C; Hosoi, M; Hu, S; Torino-Rodriguez, P | 1 |
| Ma, F; Ma, H; Ma, J; Shang, Q; Su, J; Wang, X; Yu, J; Zhang, T | 1 |
| Kaufman, PL; Liebmann, JM; Martin, KR; Vittitow, JL; Weinreb, RN | 1 |
| Boboridis, KG; Holló, G; Irkec, M; Katsanos, A; Konstas, AGP | 1 |
| Heah, T; Katz, LJ; Kopczynski, CC; McLaurin, E; Novack, GD; Ramirez-Davis, N; Serle, JB; Usner, DW | 1 |
| K R, A; Nair, RV; Nair, SC; S, S; Suresh, A | 1 |
| Kim, YY; Na, KH; Park, JH; Yoo, C | 1 |
| Agnifili, L; Brescia, L; Fasanella, V; Mastropasqua, L; Mastropasqua, R; Oddone, F; Scatena, B | 1 |
| Gouws, P; Oliphant, H | 1 |
| Samuelson, TW | 2 |
| Carleton, B; Etminan, M; Mikelberg, FS; Wendel, C; Zakrzewski, H | 1 |
| Hathout, RM; Mansour, S; Shokry, M | 1 |
| Inoue, K; Ishida, K; Tomita, G | 1 |
| Chiang, A; Ehmann, D; Gao, X; Ho, AC; Hsu, J; Obeid, A; Park, CH; Sridhar, J | 1 |
| Hashimoto, M; Hizaki, H; Kuwayama, Y; Otsuka, N; Suzuki, K | 1 |
| Bello, TO; Ogunleye, T; Olawoye, OO; Sarimiye, TF | 1 |
| Holló, G; Hommer, A; Schmidl, D | 1 |
| Agnifili, L; Brescia, L; Mastropasqua, L | 1 |
| Paul, S; Sangma, C; Sarma, P; Sharma, M; Tayab, S | 1 |
| Almobarak, F; Edward, DP; Rahmathullah, R; Robin, AL; Stagg, BC; Stein, JD; Zhao, PY | 1 |
| Bobic-Radovanovic, A; Bozic, M; Knezevic, M; Marjanovic, I; Stojkovic, M | 1 |
| Hwang, CK; Kim, BJ; Kolomeyer, AM | 1 |
| Baudouin, C; Belkacem, S; Derdour, A; Garout, R; Ghroud, N; Kherroubi, R; Lazreg, S; Merad, Z; Meziane, M; Nouri, MT; Ouhadj, O; Tiar, M | 1 |
| Abdel-Hafez, SM; Amr, A; Ateyya, T; Gad, HA; Hathout, RM; Khalil, N; Metwally, AA; Nasr, S; Nasser, N; Yasser, N | 1 |
| Chen, R; Fathollahzadeh, N; Lin, SC; Moghimi, S; Weinreb, RN | 1 |
| Bhisitkul, RB; Bloomer, MM; Cao, Y; Desai, TA; Kim, J; Konichi da Silva, NR; Phone, A; Samy, KE | 1 |
| Desai, AR; Maulvi, FA; Patil, RJ; Ranch, KM; Shah, DO; Shah, SA; Shukla, MR; Vaidya, RJ; Vyas, BA | 1 |
| Heah, T; Kahook, MY; Kim, T; Kopczynski, CC; Mah, FS; Novack, GD; Raizman, MB; Ramirez-Davis, N; Serle, JB; Usner, DW | 1 |
| Fan, S; Gilbert, J; Gulati, V; Kazemi, A; Kristoff, T; McLaren, JW; Moroi, SE; Reed, DM; Sit, AJ; Toris, CB; Trese, MGJ | 1 |
| Bacharach, J; Braswell, P; Heah, T; Khouri, AS; Kopczynski, CC; Lewis, RA; Serle, JB; Usner, DW | 1 |
| Hayashi, K; Manabe, SI; Sato, T; Yoshida, M | 1 |
| Brown, GC; Brown, MM | 1 |
| Bourne, RRA; Kaarniranta, K; Lorenz, K; Ropo, A; Traverso, CE; Vuorinen, J | 1 |
| Bhika, RE; Meyer, D; van der Merwe, EB | 1 |
| Akaishi, T; Fuwa, M; Kato, M; Mieda, M; Shimazaki, A; Taniguchi, T; Yamashita, N | 1 |
| Boevé, MH; de Gee, R; Djajadiningrat-Laanen, SC; Elders, DJ; Koele, LE; Slenter, IJM; Vermeer, LW | 1 |
| Bu, R; Feng, S; Ge, Y; Gou, J; He, H; Tang, X; Wang, J; Xu, J; Yin, T; Zhang, A; Zhang, Y | 1 |
| Jin, SW; Joh, HJ | 1 |
| Aptel, F; Astakhov, YS; Clarke, J; Coupier, L; Csutak, A; Jugaste, T; Lavín-Dapena, C; Moreno-Montañés, J; Nordmann, JP; Pfeiffer, N; Schmickler, S; Stalmans, I; Volksone, L; Żarnowski, T | 1 |
| Alemzadeh, SA; Anvari, P; Falavarjani, KG; Habibi, A; Hadi, Y; Jafari, S; Modarres, M; Parvaresh, MM | 1 |
| Kawasaki, R; Maekawa, S; Nakazawa, T; Omodaka, K; Takahashi, H; Tsuda, S; Yokoyama, Y | 1 |
| Isakov, IN; Kolbasko, AV; Makogon, SI; Onishchenko, AL | 1 |
| Jung, JH; Kim, SI; Lee, JE; Lee, SM; Shin, J | 1 |
| Schlote, T | 1 |
| Chung, IY; Han, YS; Kim, GN; Park, JM; Seo, SW; Yoo, JM | 1 |
| Balbaba, M; Çelebi, S; Ulaş, F | 1 |
| Prokosch, V; Schallenberg, M; Thanos, S | 1 |
| Feke, GT; Pasquale, LR; Rhee, DJ; Turalba, AV | 1 |
| Giannopoulos, T; Haidich, AB; Holló, G; Konidaris, V; Konstas, AG; Mikropoulos, DG; Paschalinou, E; Samples, JR; Voudouragkaki, IC | 1 |
| Dimopoulos, AT; Empeslidis, T; Haidich, AB; Holló, G; Konstas, AG; Mikropoulos, DG; Ritch, R; Teus, MA | 1 |
| Hossain, MS; Islam, MS; Khaleque, MA; Khan, N; Uddin, MS | 1 |
| Hong, SJ; Lai, YH; Wu, KY; Wu, PC | 1 |
| Irkec, M; Katsanos, A; Konstas, AG; Mocan, MC; Voudouragkaki, IC | 1 |
| Baser, EF; Gülhan, C; Öztürk, B; Seymenoğlu, G | 1 |
| Oláh, Z; Veselovský, J | 4 |
| Cabarga, C; Casado, A; de la Fuente, MA; Muñoz-Negrete, FJ | 1 |
| Calles, JA; Diebold, Y; Lopez-García, A; Palma, SD; Tártara, LI; Vallés, EM | 1 |
| Enoki, T; Hirota, N; Kanda, T; Kojima, T; Mizukawa, A; Sato, H; Shoji, T; Takeuchi, M | 1 |
| Akat, PB; Jain, SS; Joshi, SR; Karande, VB; Ramanand, JB; Ramanand, SJ | 1 |
| Bagaglia, SA; Fogagnolo, P; Frezzotti, P; Haka, G; Iester, M; Menicacci, C; Mittica, P; Motolese, E; Motolese, I; Rossetti, L | 1 |
| Karaśkiewicz, J; Lubiński, W; Penkala, K | 1 |
| Nixon, DR | 1 |
| Bhattacharya, SS; Ghosh, A; Hegde, RR; Verma, A | 1 |
| Apostolopoulos, M; Georgalas, I; Koutsandrea, C; Papaconstantinou, D; Tsikripis, P | 1 |
| Akçali, G; Bozkurt, KT; Güney, E; Sezgin Akçay, Bİ; Unlü, C | 1 |
| Arunachalam, C | 1 |
| Bernardo, FP; Gomes, B; Marques, FP; Portes, AL; Safady, MV; Santhiago, MR; Turiel, PR | 1 |
| Coban, DT; Erol, MK; Yucel, O | 1 |
| He, M; Huang, W; Wang, W | 1 |
| Hirota, A; Ichioka, I; Kanamoto, T; Kimura, W; Kiuchi, Y; Miyoshi, T; Mukai, S; Nagaya, M; Onishi, T; Osada, K; Suchiro, T; Yoshi, H | 1 |
| Baršauskaitė, R; Dilienė, V; Harris, A; Janulevičienė, I; Kuzmienė, L; Šiaudvytytė, L; Siesky, B | 1 |
| Abegão Pinto, L; Gerlier, L; Stalmans, I; Vandewalle, E | 1 |
| Choi, CY; Kim, CY; Kim, JM; Shim, SH | 1 |
| De Moraes, CG; Furlanetto, RL; Gardiner, SK; Greenfield, DS; Krupin, T; Liebmann, JM; Ritch, R; Teng, CC | 1 |
| Cheng, JW; Ge, YR; Lou, H; Wei, RL; Zong, Y | 1 |
| Bejanian, M; Gil Pina, R; Goldberg, I; Lanzagorta-Aresti, A; Liu, C; Schiffman, RM | 1 |
| Antón López, A; Holló, G; Hommer, A; Ropo, A | 1 |
| Figus, M; Fogagnolo, P; Frezzotti, P; Iester, M; Motolese, I; Perdicchi, A; Telani, S | 1 |
| Ghahari, E; Pakravan, M; Rad, SS; Yaseri, M; Yazdani, S | 1 |
| Marques, A | 1 |
| Ando, T; Hamada, R; Hamasaki, Y; Hataya, H; Honda, M; Ishikura, K; Kawaguchi, E; Miura, M; Morikawa, Y; Nagaoka, Y; Noda, E; Sakai, T | 1 |
| Agnifili, L; Di Staso, S; Fasanella, V; Lanzini, M; Mastropasqua, L; Mastropasqua, R; Pedrotti, E | 1 |
| Boboridis, KG; Dragoumis, ND; Giannopoulos, T; Haidich, AB; Kahook, MY; Konstas, AG; Makridis, AK; Paschalinou, E; Voudouragkaki, IC | 1 |
| Abegāo Pinto, L; Lequeu, I; Stalmans, I; Theuwis, K; Vandewalle, E | 1 |
| Garg, SJ; Gerstenblith, AT; Hsu, J; London, NJ; Maguire, JI; Park, C; Sivalingam, A; Spirn, MJ | 1 |
| Alezzandrini, A; Alfaro, R; Hubatsch, D | 1 |
| Bautista, D; Chew, PT; Khoo, AL; Lim, BP; Lin, L; Sng, CC; Teng, M; Wong, HT; Wu, TS; Yip, LW; Zhao, YJ | 1 |
| Holló, G; Huttunen, T; Pfeiffer, N; Ropo, A; Tuominen, J; Vuorinen, J | 1 |
| Özyol, E; Özyol, P | 1 |
| Kumar, MS; Mishra, D; Sinha, BP | 1 |
| Astakhov, Y; Boiko, E; Liinamaa, J; Lorenz, K; Pfeiffer, N; Ropo, A; Saarela, V; Traverso, CE; Uusitalo, H | 1 |
| Agarwal, P; Agarwal, R; Ismail, NM; Kannan Kutty, M; Kapitonova, MY; Razali, N; Salmah Bakar, N; Smirnov, A | 1 |
| Allbaugh, RA; Ben-Shlomo, G; Dufour, VL; Flinn, AM; Griggs, AN; Peterson, CS; Tofflemire, KL; Whitley, DR; Whitley, EM | 1 |
| García-López, A; Hartleben, C; Jiménez-Román, J; Paczka, JA | 1 |
| Hirano, Y; Nozaki, M; Ogura, S; Ogura, Y; Orazbekov, L; Usui, H; Yasukawa, T | 1 |
| Boehm, A; Centofanti, M; Fogagnolo, P; Goldblum, D; Karabatsas, CH; Rossetti, L; Sacchi, M; Topouzis, F; Vetrugno, M; Vorwerk, C | 1 |
| Liu, D; Pan, W; Wang, QM; Wang, X; Yang, X; Ye, T; Yu, S; Zhang, W | 1 |
| Holló, G; Katsanos, A | 1 |
| Guzman-Aranguez, A; Loma, P; Perez de Lara, MJ; Pintor, J | 1 |
| Alagoz, G; Altun, G; Celik, E; Turkoglu, EB | 1 |
| Avalos-Franco, N; Castellar-Cerpa, J; García Sánchez, J; Sáenz-Francés, F; Santos-Bueso, E | 1 |
| Alvarez Igarzabal, CI; González, A; Palma, SD; Tártara, LI | 1 |
| Cheng, JW; Lou, H; Wang, H; Wei, RL; Zong, Y | 1 |
| Chistyakov, TA; Kuzmin, AG; Lipatov, DV; Tolkacheva, AA | 1 |
| Carbia, BE; Chauhan, A; Hsu, KH; Plummer, C | 1 |
| Liu, KL; Lwin, NC; Ng, XW; Veluchamy, AB; Venkatraman, SS; Wong, TT | 1 |
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| Andrew, R; Bergamini, MV; Davis, AA; Dickerson, J; Landry, T; Mallick, S; Netland, PA; Robertson, SM; Silver, L; Sullivan, EK; Weiner, A | 1 |
| Cole, C; Garzozi, H; Harris, A; Jonescu-Cuypers, CP; Kagemann, L; Martin, B; Nowacki, EA | 1 |
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| Aarsland, T; Dickstein, K; Hapnes, R | 1 |
| Cunha-Vaz, J; Goldberg, I; Jakobsen, JE; Nordmann, JP; Sullivan, EK; Trost, E | 1 |
| Davis, AA; Landry, T; Orengo-Nania, S; Silver, LH; Von Tress, M; Weiner, A | 1 |
| Kapik, B; Mertz, B; Nordmann, JP; Schwenninger, C; Shams, N; Yannoulis, NC | 1 |
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| Brubaker, RF; McCannel, CA; Scanlon, PD; Thibodeau, S | 1 |
| Calogero, G; Caprilli, A; Quaranta-Leoni, FM; Ricci, B | 1 |
| Beekhuis, WH; Huige, WM; Remeijer, L; Rijneveld, WJ; Schrage, N | 1 |
| Béchetoille, A; Gerling, J; Grehn, F; Greve, E; Gunning, F; Jaquet-Müller, F; Lippa, EA; Pfeiffer, N | 1 |
| Allen, RC; Bahr, RL; Cohen, JS; Delehanty, JT; Hetherington, JN; Hoskins, HD; Lewis, RA; Noblin, JE; Shields, MB; Stewart, WC | 1 |
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| Caprioli, J; Elman, J; Mead, A; Petillo, J; Rosanelli, EG; Sears, M; Shields, R | 1 |
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| Fukado, Y; Inatomi, M; Koide, R; Maeda, I; Oguchi, K; Uchida, E; Ueda, T; Yasuhara, H | 1 |
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| Batoosingh, AL; David, R; Duzman, E; Freeman, MI; Lee, PF; Novack, GD | 1 |
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| Allen, RC; Kaplan, G; Long, D; Lue, JC; Novack, GD; Robin, AL | 1 |
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95 review(s) available for timolol and Intraocular Pressure
| Article | Year |
|---|---|
New approaches to antiglaucoma therapy.
Topics: Adenosine; Animals; Antihypertensive Agents; Cannabinoids; Drug Design; Endothelins; Glaucoma; Guanylate Cyclase; Humans; Intraocular Pressure; Neuroprotective Agents | 1997 |
Intraocular pressure-lowering efficacy and ocular safety of Rho-kinase inhibitor in glaucoma: a meta-analysis and systematic review of prospective randomized trials.
Topics: Antihypertensive Agents; Double-Blind Method; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Randomized Controlled Trials as Topic; rho-Associated Kinases; Timolol; Treatment Outcome | 2022 |
Comparison of Netarsudil/Latanoprost Therapy with Latanoprost Monotherapy for Lowering Intraocular Pressure: A Systematic Review and Meta-analysis.
Topics: Antihypertensive Agents; Benzoates; beta-Alanine; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; rho-Associated Kinases; Timolol; Treatment Outcome | 2022 |
[Xalacom: possibilities and advantages of the drug in the treatment of patients with glaucoma].
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quality of Life; Timolol; Treatment Outcome | 2022 |
[ROCK (RHO-KINASE INHIBITORS) FOR THE TREATMENT OF OPEN-ANGLE GLAUCOMA AND OCULAR HYPERTENSION].
Topics: Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Timolol; Treatment Outcome; United States | 2023 |
The efficacy of the fixed combination of latanoprost and timolol versus other fixed combinations for primary open-angle glaucoma and ocular hypertension: A systematic review and meta-analysis.
Topics: Antihypertensive Agents; Bimatoprost; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2020 |
Dorzolamide/Timolol Fixed Combination: Learning from the Past and Looking Toward the Future.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2021 |
Short-term efficacy of latanoprostene bunod for the treatment of open-angle glaucoma and ocular hypertension: a systematic literature review and a network meta-analysis.
Topics: Amides; Antihypertensive Agents; Bayes Theorem; Betaxolol; Bimatoprost; Brimonidine Tartrate; Carteolol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Network Meta-Analysis; Ocular Hypertension; Prostaglandins A; Prostaglandins F, Synthetic; Timolol; Travoprost | 2022 |
Comparative efficacy and safety of preserved versus preservative-free beta-blockers in patients with glaucoma or ocular hypertension: a systematic review.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol | 2022 |
Ophthalmic Timolol Hallucinations: A Case Series and Review of the Literature.
Topics: Administration, Topical; Aged; Aged, 80 and over; Antihypertensive Agents; Female; Glaucoma; Hallucinations; Humans; Intraocular Pressure; Ophthalmic Solutions; Timolol | 2017 |
Glaucoma Drug Therapy in Pregnancy: Literature Review and Teratology Information Service (TIS) Case Series.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Congenital Abnormalities; Counseling; Drug Therapy, Combination; Female; Glaucoma; Humans; Information Services; Intraocular Pressure; Italy; Pregnancy; Pregnancy Outcome; Prospective Studies; Teratology; Timolol | 2018 |
Preservative-Free Prostaglandin Analogs and Prostaglandin/Timolol Fixed Combinations in the Treatment of Glaucoma: Efficacy, Safety and Potential Advantages.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Benzalkonium Compounds; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins; Prostaglandins, Synthetic; Retrospective Studies; Timolol | 2018 |
Anterior chamber fibrinoid syndrome after cataract extraction in a patient on ibrutinib for B-cell chronic lymphocytic leukemia: a case report and review of the literature.
Topics: Adenine; Administration, Topical; Aged; Anterior Chamber; Antihypertensive Agents; Antineoplastic Agents; Brimonidine Tartrate; Cataract Extraction; Humans; Intraocular Pressure; Leukemia, Lymphocytic, Chronic, B-Cell; Male; Phacoemulsification; Piperidines; Prednisolone; Pyrazoles; Pyrimidines; Sulfonamides; Syndrome; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2018 |
[Mode of action, clinical profile and significance of beta-blockers in antiglaucoma therapy].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Cost-Benefit Analysis; Dose-Response Relationship, Drug; Drug Interactions; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Timolol; Treatment Outcome | 2013 |
Latanoprost/timolol fixed combination for the treatment of glaucoma.
Topics: Animals; Antihypertensive Agents; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2013 |
Electrophysiological tests in evaluation of glaucoma and ocular hypertension treatment--up to date knowledge. A review.
Topics: Acetazolamide; Dose-Response Relationship, Drug; Electroretinography; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Trabeculectomy; Treatment Outcome | 2013 |
Efficacy and tolerability of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials.
Topics: Antihypertensive Agents; Drug Tolerance; Female; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2013 |
Efficacy and tolerability of latanoprost compared with timolol in the treatment of patients with chronic angle-closure glaucoma.
Topics: Antihypertensive Agents; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Treatment Outcome | 2014 |
Comparative efficacy and tolerability of topical prostaglandin analogues for primary open-angle glaucoma and ocular hypertension.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost | 2014 |
Fixed-dose combination of tafluprost and timolol in the treatment of open-angle glaucoma and ocular hypertension: comparison with other fixed-combination products.
Topics: Adrenergic beta-Antagonists; Amides; Cloprostenol; Double-Blind Method; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F; Randomized Controlled Trials as Topic; Timolol | 2014 |
Safety and tolerability of the tafluprost/timolol fixed combination for the treatment of glaucoma.
Topics: Antihypertensive Agents; Conjunctival Diseases; Drug Combinations; Glaucoma; Humans; Hyperemia; Intraocular Pressure; Medication Adherence; Prostaglandins F; Timolol | 2015 |
Efficacy and tolerability of prostaglandin-timolol fixed combinations: an updated systematic review and meta-analysis.
Topics: Antihypertensive Agents; Bimatoprost; Drug Combinations; Glaucoma; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Timolol; Travoprost | 2015 |
Medical management of glaucoma: focus on ophthalmologic drug delivery systems of timolol maleate.
Topics: Antihypertensive Agents; Biological Availability; Disease Management; Drug Delivery Systems; Emulsions; Epithelium, Corneal; Glaucoma; Humans; Hydrogels; Intraocular Pressure; Microspheres; Nanoparticles; Ocular Hypertension; Ophthalmic Solutions; Permeability; Polymers; Timolol | 2017 |
Preservative-free tafluprost/timolol fixed combination: a new opportunity in the treatment of glaucoma.
Topics: Antihypertensive Agents; Disease Management; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F; Quality of Life; Timolol | 2016 |
Efficacy, safety, and current applications of brimonidine.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Timolol; Treatment Outcome | 2008 |
[Fixed combinations of glaucoma medications].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2008 |
Efficacy and tolerability of latanoprost compared to dorzolamide combined with timolol in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized, controlled trials.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2009 |
Intraocular pressure measurements throughout the 24 h.
Topics: Carbonic Anhydrase Inhibitors; Circadian Rhythm; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Prostaglandins; Timolol; Trabeculectomy | 2009 |
[The role of Cosopt in glaucoma treatment].
Topics: Antihypertensive Agents; Drug Combinations; Evidence-Based Medicine; Glaucoma; Humans; Intraocular Pressure; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
Assessing the efficacy of latanoprost vs timolol using an alternate efficacy parameter: the intervisit intraocular pressure range.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Risk Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2009 |
Meta-analysis of medical intervention for normal tension glaucoma.
Topics: Aged; Amides; Antihypertensive Agents; Betaxolol; Bimatoprost; Brimonidine Tartrate; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Travoprost | 2009 |
Systematic review of intraocular pressure-lowering effects of adjunctive medications added to latanoprost.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Databases, Factual; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Optic Nerve Diseases; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol | 2009 |
Is the medication used to achieve the target intraocular pressure in glaucoma therapy of relevance?--an exemplary analysis on the basis of two beta-blockers.
Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans; Intraocular Pressure; Timolol; Visual Fields | 2010 |
[Drug therapy for glaucoma].
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Disease Progression; Glaucoma; Humans; Intraocular Pressure; Muscarinic Antagonists; Pilocarpine; Timolol | 2009 |
[Bimatoprost therapy in glaucoma].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Evidence-Based Medicine; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost; Treatment Outcome | 2009 |
WITHDRAWN: Interventions for normal tension glaucoma.
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Vincamine | 2010 |
Fixed combinations of dorzolamide-timolol and brimonidine-timolol in the management of glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Patient Selection; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2010 |
Brinzolamide 1%/timolol 0.5%: safety and efficacy of a new fixed-combination IOP-lowering product for glaucoma.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Glaucoma; Humans; Intraocular Pressure; Sulfonamides; Thiazines; Timolol; Treatment Outcome | 2010 |
Travoprost/timolol fixed combination in the management of open-angle glaucoma: a clinical review.
Topics: Animals; Antihypertensive Agents; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Timolol; Travoprost | 2011 |
Metabolism of ophthalmic timolol: new aspects of an old drug.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2C19; Cytochrome P-450 CYP2D6; Eye; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Liver; Timolol | 2011 |
Recent clinical pearls from clinical trials in glaucoma.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Filtering Surgery; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Low Tension Glaucoma; Ocular Hypertension; Quinoxalines; Timolol; Tonometry, Ocular | 2012 |
[Azarga, a new and useful fixed combination in glaucoma treatment].
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome; Vision, Ocular | 2011 |
[The latest developments in glaucoma therapy using fixed combination products].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate, Timolol Maleate Drug Combination; Carbonic Anhydrase Inhibitors; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiazines; Thiophenes; Timolol; Travoprost; Treatment Outcome | 2011 |
[Fixed combination of topical prostaglandin analogue in glaucoma treatment].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Carbonic Anhydrase Inhibitors; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Optic Nerve; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Timolol; Travoprost; Treatment Outcome; Visual Fields | 2011 |
Intraocular pressure-lowering effects of commonly used fixed-combination drugs with timolol: a systematic review and meta-analysis.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Drug Combinations; Humans; Intraocular Pressure; Middle Aged; Randomized Controlled Trials as Topic; Timolol | 2012 |
Prostaglandin analogs and timolol-fixed versus unfixed combinations or monotherapy for open-angle glaucoma: a systematic review and meta-analysis.
Topics: Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Ocular Hypertension; Prostaglandins; Timolol | 2013 |
Efficacy and tolerability of fixed combination of brimonidine 0.2%/timolol 0.5% compared with fixed combination of dorzolamide 2%/timolol 0.5% in the treatment of patients with elevated intraocular pressure: a meta-analysis of randomized controlled trials
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2013 |
The effect of latanoprost on circadian intraocular pressure.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2002 |
Bimatoprost and travoprost: a review of recent studies of two new glaucoma drugs.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost | 2002 |
Latanoprost versus combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
Combined therapy of pilocarpine or latanoprost with timolol versus latanoprost monotherapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Muscarinic Agonists; Ocular Hypertension; Pilocarpine; Prostaglandins F, Synthetic; Timolol | 2002 |
[Comparison of latanoprost monotherapy with timolol-dorzolamide combination in patients with open-angle glaucoma or ocular hypertension].
Topics: Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2002 |
Myopia: attempts to arrest progression.
Topics: Accommodation, Ocular; Adolescent; Adult; Atropine; Biofeedback, Psychology; Child; Contact Lenses; Disease Progression; Eye Movements; Eyeglasses; Humans; Intraocular Pressure; Medicine, Chinese Traditional; Myopia; Ophthalmic Solutions; Pirenzepine; Timolol; Tropicamide | 2002 |
Four years later: a clinical update on latanoprost.
Topics: Antihypertensive Agents; Aqueous Humor; Blood Flow Velocity; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Eye; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
Latanoprost : an update of its use in glaucoma and ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Combinations; Eye Diseases; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2003 |
Short- and long-term safety of glaucoma drugs.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Glaucoma; Humans; Intraocular Pressure; Safety; Timolol | 2002 |
Interventions for normal tension glaucoma.
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Vincamine | 2003 |
Pooled-data analysis of three randomized, double-masked, six-month studies comparing intraocular pressure-reducing effects of latanoprost and timolol in patients with ocular hypertension.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Retrospective Studies; Timolol; Treatment Outcome | 2003 |
An evaluation of the fixed-combination of latanoprost and timolol for use in open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol | 2004 |
[Timolol topical ophthalmic combination].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
[Latanoprost topical ophthalmic combinations].
Topics: Acetazolamide; Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Dinoprost; Drug Combinations; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2004 |
Intraocular pressure-lowering effects of all commonly used glaucoma drugs: a meta-analysis of randomized clinical trials.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Drug Prescriptions; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prostaglandins, Synthetic; Randomized Controlled Trials as Topic; Timolol | 2005 |
Glaucoma pharmacotherapy: implications for flying fitness.
Topics: Acetazolamide; Adrenergic beta-Antagonists; Aerospace Medicine; Carbonic Anhydrase Inhibitors; Contraindications; Glaucoma; Humans; Intraocular Pressure; Miotics; Physical Fitness; Pilocarpine; Safety; Task Performance and Analysis; Timolol; Visual Perception | 2005 |
Analytic review of bimatoprost, latanoprost and travoprost in primary open angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Amides; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost; Treatment Outcome | 2005 |
Cost considerations in the medical management of glaucoma in the US: estimated yearly costs and cost effectiveness of bimatoprost compared with other medications.
Topics: Adrenergic beta-Antagonists; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Cost-Benefit Analysis; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Treatment Outcome; United States | 2006 |
The fading of reported effectiveness. A meta-analysis of randomised controlled trials.
Topics: Adrenergic beta-Antagonists; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Cholesterol, LDL; Drug Evaluation; Heptanoic Acids; Humans; Intraocular Pressure; Latanoprost; Pravastatin; Prostaglandins F, Synthetic; Publication Bias; Pyrroles; Randomized Controlled Trials as Topic; Sample Size; Selection Bias; Time Factors; Timolol; Treatment Outcome | 2006 |
Intraocular pressure-lowering effect of adding dorzolamide or latanoprost to timolol: a meta-analysis of randomized clinical trials.
Topics: Antihypertensive Agents; Databases, Factual; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2007 |
Travoprost compared with other prostaglandin analogues or timolol in patients with open-angle glaucoma or ocular hypertension: meta-analysis of randomized controlled trials.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Dinoprost; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost | 2006 |
Use of fixed-dose combination drugs for the treatment of glaucoma.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Geriatrics; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Patient Compliance; Prostaglandins; Timolol | 2007 |
Meta-analysis of 24-hour intraocular pressure studies evaluating the efficacy of glaucoma medicines.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2008 |
Shortterm "escape" and longterm "drift." The dissipation effects of the beta adrenergic blocking agents.
Topics: Adrenergic beta-Antagonists; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Receptors, Adrenergic, beta; Tachyphylaxis; Time Factors; Timolol | 1983 |
Advances in ocular pharmacology.
Topics: Animals; Cannabis; Carbachol; Cytochalasin B; Epinephrine; Eye; Eye Diseases; Glaucoma; Humans; Idoxuridine; Interferons; Intraocular Pressure; Keratitis; Membranes, Artificial; Pharmaceutical Preparations; Timolol; Trifluridine; Vidarabine; Virus Diseases | 1980 |
Mechanisms of topical drugs used in the control of open angle glaucoma.
Topics: Animals; Cats; Ciliary Body; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Rabbits; Timolol | 1980 |
Topical ophthalmic beta blockers: a comparative review.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Carteolol; Drug Tolerance; Glaucoma; Humans; Intraocular Pressure; Levobunolol; Metipranolol; Ophthalmic Solutions; Timolol | 1993 |
[Eye-pressure tonometry in prevention of glaucoma].
Topics: Equipment Design; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Reference Values; Timolol; Tonometry, Ocular; Visual Fields | 1993 |
The preclinical pharmacology of dorzolamide hydrochloride, a topical carbonic anhydrase inhibitor.
Topics: Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Dogs; Drug Combinations; Drug Evaluation, Preclinical; Glaucoma; Intraocular Pressure; Macaca; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Timolol | 1996 |
Clinical dose-regimen studies with latanoprost, a new ocular hypotensive PGF2 alpha analogue.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 1997 |
Reduced intraocular pressure and increased ocular perfusion pressure in normal tension glaucoma: a review of short-term studies with three dose regimens of latanoprost treatment.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Circadian Rhythm; Dose-Response Relationship, Drug; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 1997 |
The additive intraocular pressure-lowering effect of latanoprost in combined therapy with other ocular hypotensive agents.
Topics: Acetazolamide; Adrenergic Agonists; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Timolol | 1997 |
Phase III latanoprost studies in Scandinavia, the United Kingdom and the United States.
Topics: Adrenergic beta-Antagonists; Clinical Trials, Phase III as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Scandinavian and Nordic Countries; Timolol; United Kingdom; United States | 1997 |
Brimonidine: a new alpha2-adrenoreceptor agonist for glaucoma treatment.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Betaxolol; Brimonidine Tartrate; Clinical Trials as Topic; Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Timolol; Trabeculectomy | 1997 |
Medical treatment as the initial therapy for open-angle glaucoma.
Topics: Contraindications; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Timolol; Trabeculectomy | 1992 |
Should laser trabeculoplasty be the initial mode of treatment in open-angle glaucoma?
Topics: Contraindications; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Timolol; Trabeculectomy | 1992 |
Assessment of ocular hypotensive mechanisms and additivity of antiglaucoma drugs in humans.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aqueous Humor; Brimonidine Tartrate; Clonidine; Drug Synergism; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 1999 |
Topical dorzolamide 2%/timolol 0.5%: a review of its use in the treatment of open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Timolol; Vision, Ocular | 2000 |
Bimatoprost: a member of a new class of agents, the prostamides, for glaucoma management.
Topics: Amides; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Prostaglandins F, Synthetic; Timolol | 2001 |
Meta-analysis of randomised controlled trials comparing latanoprost with timolol in the treatment of patients with open angle glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Confidence Intervals; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Ocular Hypertension; Pigmentation Disorders; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Risk Factors; Single-Blind Method; Timolol; Treatment Outcome | 2001 |
Topical bimatoprost: a review of its use in open-angle glaucoma and ocular hypertension.
Topics: Administration, Topical; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctival Diseases; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma, Open-Angle; Intraocular Pressure; Latanoprost; Lipids; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2002 |
Travoprost--a new prostaglandin analogue for the treatment of glaucoma.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Racial Groups; Receptors, Prostaglandin; Timolol; Travoprost | 2002 |
Myopia progression in young school children. A prospective study of myopia progression and the effect of a trial with bifocal lenses and beta blocker eye drops.
Topics: Child; Eyeglasses; Female; Humans; Intraocular Pressure; Male; Myopia; Ophthalmic Solutions; Prospective Studies; Timolol | 1991 |
Pharmacologic effects of beta-blocking agents used in the management of glaucoma.
Topics: Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Metipranolol; Propanolamines; Solubility; Timolol | 1989 |
Betaxolol.
Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Time Factors; Timolol | 1989 |
Pharmaceutical agents and the prevention or reduction of progressive myopia.
Topics: Atropine; Epinephrine; Humans; Intraocular Pressure; Myopia; Ophthalmic Solutions; Sclera; Timolol; Tropicamide | 1988 |
[Modification in amplitude of nycthemeral changes in intraocular pressure under timolol].
Topics: Adult; Circadian Rhythm; Female; Humans; Intraocular Pressure; Male; Timolol | 1988 |
Glaucoma: an overview.
Topics: Aged; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cholinesterase Inhibitors; Epinephrine; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Optic Nerve; Pilocarpine; Risk; Time Factors; Timolol; Trabecular Meshwork; Visual Acuity; Visual Fields | 1986 |
702 trial(s) available for timolol and Intraocular Pressure
| Article | Year |
|---|---|
Twelve-month efficacy and safety of omidenepag isopropyl, a selective EP2 agonist, in open-angle glaucoma and ocular hypertension: the RENGE study.
Topics: Antihypertensive Agents; Double-Blind Method; Glaucoma, Open-Angle; Glycine; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pyrazoles; Pyridines; Timolol; Treatment Outcome | 2021 |
The Effects of Topical Timolol and Latanoprost on Calculated Ocular Perfusion Pressure in Nonglaucomatous Volunteers.
Topics: Blood Pressure; Cross-Over Studies; Female; Healthy Volunteers; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Physiological Phenomena; Ophthalmic Solutions; Prospective Studies; Timolol | 2021 |
Phase 3, Randomized, 20-Month Study of the Efficacy and Safety of Bimatoprost Implant in Patients with Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 2).
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Dose-Response Relationship, Drug; Double-Blind Method; Drug Implants; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Young Adult | 2021 |
Comparing the effects and safety of dorzolamide hydrochloride + timolol maleate versus brimonidine after neodymium-doped yttrium aluminium garnet laser capsulotomy posterior capsule opacification.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Capsule Opacification; Glaucoma; Humans; Intraocular Pressure; Lasers, Solid-State; Neodymium; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Yttrium | 2022 |
Effect of Topically Applied 0.5% Apraclonidine Versus 0.5% Timolol Maleate on Intraocular Pressure of Healthy Horses.
Topics: Adrenergic alpha-Agonists; Animals; Clonidine; Double-Blind Method; Female; Horse Diseases; Horses; Intraocular Pressure; Lubricant Eye Drops; Ocular Hypertension; Timolol | 2022 |
Intraocular Peak Pressure in Patients Under Treatment With Fixed Combination of Bimatoprost/Timolol/Brimonidine Once Daily Versus Twice Daily.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Water | 2022 |
Comparison of the Effects of Latanoprostene Bunod and Timolol on Retinal Blood Vessel Density: A Randomized Clinical Trial.
Topics: Glaucoma, Open-Angle; Humans; Intraocular Pressure; Macula Lutea; Ocular Hypertension; Prostaglandins F, Synthetic; Retinal Vessels; Timolol; Tomography, Optical Coherence | 2022 |
Changing from preserved, to preservative-free cyclosporine 0.1% enhanced triple glaucoma therapy: impact on ocular surface disease-a randomized controlled trial.
Topics: Antihypertensive Agents; Cyclosporins; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Matrix Metalloproteinase 9; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Timolol; Treatment Outcome | 2023 |
Randomized Multicenter Clinical Trial Comparing 0.1% Brimonidine/0.5% Timolol Versus 1% Dorzolamide/0.5% Timolol as Adjuncts to Prostaglandin Analogues: Aibeta Crossover Study.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Prostaglandins, Synthetic; Timolol | 2023 |
New technique to reduce systemic side effects of timolol eye drops: The tissue press method-Cross-over clinical trial.
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Pressure; Bradycardia; Cross-Over Studies; Double-Blind Method; Drug-Related Side Effects and Adverse Reactions; Dyspnea; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Nasolacrimal Duct; Ocular Absorption; Ophthalmic Solutions; Timolol | 2020 |
Efficacy And Safety Of Travoprost Versus Timolol To Treat Early-Onset Ocular Hypertension Secondary To Vitrectomy: A Randomized Trial.
Topics: Female; Humans; Inflammation; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Risk Factors; Single-Blind Method; Timolol; Travoprost; Vitrectomy | 2019 |
Fixed-combination Bimatoprost/Brimonidine/Timolol in Glaucoma: A Randomized, Masked, Controlled, Phase III Study Conducted in Brazil
Topics: Aged; Antihypertensive Agents; Bimatoprost; Brazil; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 2020 |
Effect of Adjuvant Topical Dorzolamide-Timolol vs Placebo in Neovascular Age-Related Macular Degeneration: A Randomized Clinical Trial.
Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Chemotherapy, Adjuvant; Choroidal Neovascularization; Drug Combinations; Exudates and Transudates; Female; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Ophthalmic Solutions; Placebos; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity; Wet Macular Degeneration | 2020 |
Phase 3, Randomized, 20-Month Study of Bimatoprost Implant in Open-Angle Glaucoma and Ocular Hypertension (ARTEMIS 1).
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Double-Blind Method; Drug Implants; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Tonometry, Ocular; Vitreous Body; Young Adult | 2020 |
Validation of a More Reliable Method of Eye Drop Self-Administration.
Topics: Administration, Ophthalmic; Adult; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Reproducibility of Results; Self Administration; Timolol; Tonometry, Ocular; Young Adult | 2020 |
[Preservative-free fixed combination in the treatment of open-angle glaucoma and ocular hypertension: the VISIONARY Study (EUPAS22204)].
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Russia; Timolol; Treatment Outcome | 2020 |
Pooled Efficacy and Safety Profile of Netarsudil Ophthalmic Solution 0.02% in Patients With Open-angle Glaucoma or Ocular Hypertension.
Topics: Administration, Ophthalmic; Adult; Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Timolol; Tonometry, Ocular; Treatment Outcome | 2020 |
MLIP genotype as a predictor of pharmacological response in primary open-angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Alleles; Biomarkers; Co-Repressor Proteins; Cross-Over Studies; DNA Copy Number Variations; Female; Genome-Wide Association Study; Genotype; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol | 2021 |
Comparison of the 24-h efficacy and safety of fixed combination carteolol/latanoprost and timolol/latanoprost in patients with primary open-angle glaucoma and ocular hypertension: a prospective crossover study.
Topics: Antihypertensive Agents; Carteolol; Cross-Over Studies; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2021 |
Clinical Trial: Diurnal IOP Fluctuations in Glaucoma Using Latanoprost and Timolol with Self-Tonometry.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Manometry; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2021 |
Additive effects and safety of fixed combination therapy with 1% brinzolamide and 0.5% timolol versus 1% dorzolamide and 0.5% timolol in prostaglandin-treated glaucoma patients.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Follow-Up Studies; Glaucoma, Open-Angle; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins, Synthetic; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Evaluation of the effects on choroidal thickness of bimatoprost 0.03% versus a brinzolamide 1.0%/timolol maleate 0.5% fixed combination.
Topics: Adult; Aged; Antihypertensive Agents; Bimatoprost; Choroid; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Single-Blind Method; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence | 2017 |
The effect of Timolol 0.5% on the correction of myopic regression after LASIK.
Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Intraocular Pressure; Keratomileusis, Laser In Situ; Male; Myopia; Ophthalmic Solutions; Timolol; Treatment Failure | 2017 |
Multicenter, Randomized, Investigator-Masked Study Comparing Brimonidine Tartrate 0.1% and Timolol Maleate 0.5% as Adjunctive Therapies to Prostaglandin Analogues in Normal-Tension Glaucoma.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Female; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins, Synthetic; Single-Blind Method; Timolol | 2017 |
The efficacy and safety of bimatoprost/timolol maleate, latanoprost/timolol maleate, and travoprost/timolol maleate fixed combinations on 24-h IOP.
Topics: Aged; Aged, 80 and over; Bimatoprost; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Substitution; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Monitoring, Physiologic; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2018 |
Brimonidine-timolol versus brinzolamide-timolol for treatment of elevated intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2018 |
A 3-month safety and efficacy study of travoprost 0.004% ophthalmic solution compared with timolol in pediatric patients with glaucoma or ocular hypertension.
Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Double-Blind Method; Drug Therapy, Combination; Equivalence Trials as Topic; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol; Tonometry, Ocular; Travoprost | 2017 |
Latanoprostene Bunod 0.024% in Subjects With Open-angle Glaucoma or Ocular Hypertension: Pooled Phase 3 Study Findings.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Visual Acuity; Young Adult | 2018 |
Two Phase 3 Clinical Trials Comparing the Safety and Efficacy of Netarsudil to Timolol in Patients With Elevated Intraocular Pressure: Rho Kinase Elevated IOP Treatment Trial 1 and 2 (ROCKET-1 and ROCKET-2).
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzoates; beta-Alanine; Child; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2018 |
Multicenter, Randomized, Controlled Study Comparing Tafluprost/Timolol Fixed Combination with Latanoprost/Timolol Fixed Combination in Primary Open-Angle Glaucoma and Ocular Hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Japan; Latanoprost; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Young Adult | 2018 |
Efficacy and safety of preservative-free timolol 0.1% gel in open-angle glaucoma and ocular hypertension in treatment-naïve patients and patients intolerant to other hypotensive medications.
Topics: Adult; Aged; Aged, 80 and over; Algeria; Antihypertensive Agents; Drug Hypersensitivity; Drug-Related Side Effects and Adverse Reactions; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2018 |
Long-term Safety and Ocular Hypotensive Efficacy Evaluation of Netarsudil Ophthalmic Solution: Rho Kinase Elevated IOP Treatment Trial (ROCKET-2).
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; rho-Associated Kinases; Timolol; Treatment Outcome | 2019 |
Once-Daily Netarsudil Versus Twice-Daily Timolol in Patients With Elevated Intraocular Pressure: The Randomized Phase 3 ROCKET-4 Study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzoates; beta-Alanine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Tonometry, Ocular; Treatment Outcome | 2019 |
Effect of Topical Hypotensive Medications for Preventing Intraocular Pressure Increase after Cataract Surgery in Eyes with Glaucoma.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cataract; Cataract Extraction; Dose-Response Relationship, Drug; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2019 |
Changes in ocular signs and symptoms in patients switching from bimatoprost-timolol to tafluprost-timolol eye drops: an open-label phase IV study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intention to Treat Analysis; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Quality of Life; Timolol | 2019 |
The effects of topical dorzolamide 2% and brinzolamide 1%, either alone or combined with timolol 0.5%, on intraocular pressure, pupil diameter, and heart rate in healthy cats.
Topics: Animals; Cats; Cross-Over Studies; Double-Blind Method; Drug Combinations; Drug Interactions; Drug Therapy, Combination; Female; Heart Rate; Intraocular Pressure; Male; Ophthalmic Solutions; Pupil; Sulfonamides; Thiazines; Thiophenes; Timolol | 2020 |
Noninferiority of Preservative-free Versus BAK-preserved Latanoprost-timolol Fixed Combination Eye Drops in Patients With Open-angle Glaucoma or Ocular Hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzalkonium Compounds; Drug Combinations; Equivalence Trials as Topic; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol; Tonometry, Ocular; Treatment Outcome | 2019 |
Effects of Brimonidine and Timolol on the Progression of Visual Field Defects in Open-angle Glaucoma: A Single-center Randomized Trial.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Disease Progression; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol; Tonometry, Ocular; Vision Disorders; Visual Field Tests; Visual Fields | 2019 |
Effect of prophylactic intraocular pressure-lowering medication on pain during cataract surgery.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Cataract; Cloprostenol; Combined Modality Therapy; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pain; Phacoemulsification; Postoperative Period; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Travoprost | 2013 |
Effects of dorzolamide-timolol and brimonidine-timolol on retinal vascular autoregulation and ocular perfusion pressure in primary open angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2013 |
Comparison of 24-hour intraocular pressure reduction obtained with brinzolamide/timolol or brimonidine/timolol fixed-combination adjunctive to travoprost therapy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cloprostenol; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol; Travoprost | 2013 |
24-hour efficacy of the bimatoprost-timolol fixed combination versus latanoprost as first choice therapy in subjects with high-pressure exfoliation syndrome and glaucoma.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Field Tests; Visual Fields | 2013 |
Comparison of dorzolamide/timolol versus brimonidine/timolol fixed combination therapy in the management of steroid-induced ocular hypertension.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Diabetic Retinopathy; Drug Combinations; Female; Glucocorticoids; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Triamcinolone Acetonide | 2015 |
Hypotensive effect of latanoprost/timolol versus travoprost/timolol fixed combinations in NTG patients: a randomized, multicenter, crossover clinical trial.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Low Tension Glaucoma; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Timolol; Travoprost | 2013 |
Evaluation of brimonidine-timolol fixed combination in patients of primary open-angle glaucoma.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Dose-Response Relationship, Drug; Drug Therapy, Combination; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Timolol; Treatment Outcome | 2013 |
In vivo confocal microscopy of conjunctiva in preservative-free timolol 0.1% gel formulation therapy for glaucoma.
Topics: Adrenergic beta-Antagonists; Benzalkonium Compounds; Cell Count; Conjunctiva; Female; Gels; Glaucoma, Open-Angle; Goblet Cells; Humans; Intraocular Pressure; Male; Microscopy, Confocal; Middle Aged; Ocular Hypertension; Pharmaceutical Preparations; Preservatives, Pharmaceutical; Tears; Timolol; Tonometry, Ocular | 2014 |
A randomized, prospective study of bimatoprost 0.01% or travoprost/timolol in patients previously treated with latanoprost and timolol to reduce intraocular pressure.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Male; Middle Aged; Patient Preference; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Timolol; Travoprost; Treatment Outcome | 2013 |
The effect of prostaglandin analogs on the biomechanical properties and central thickness of the cornea of patients with open-angle glaucoma: a 3-year study on 108 eyes.
Topics: Aged; Antihypertensive Agents; Cornea; Corneal Pachymetry; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2013 |
The safety and efficacy of brinzolamide 1%/timolol 0.5% fixed combination versus dorzolamide 2%/timolol 0.5% in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Preference; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2013 |
[Clinical efficacy of travoprost-timolol fixed combination on ocular hypotensive agents and ocular surface agents in Japanese glaucoma patients].
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Asian People; Cloprostenol; Cornea; Dinoprost; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Patient Satisfaction; Surveys and Questionnaires; Timolol; Travoprost; Treatment Outcome | 2013 |
The effect of nebulized dorzolamide/timolol fixed combination mist versus drops on retrobulbar blood flow and intraocular pressure in glaucoma patients.
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Nebulizers and Vaporizers; Ophthalmic Solutions; Orbit; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2013 |
Diurnal intraocular pressure with bimatoprost/timolol fixed combination versus latanoprost/timolol fixed combination in healthy subjects.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Healthy Volunteers; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Risk factors for optic disc hemorrhage in the low-pressure glaucoma treatment study.
Topics: Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Female; Follow-Up Studies; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Optic Disk; Proportional Hazards Models; Quinoxalines; Retinal Hemorrhage; Risk Factors; Timolol | 2014 |
Bimatoprost 0.03%/timolol 0.5% preservative-free ophthalmic solution versus bimatoprost 0.03%/timolol 0.5% ophthalmic solution (Ganfort) for glaucoma or ocular hypertension: a 12-week randomised controlled trial.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Therapeutic Equivalency; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2014 |
Efficacy, safety, and tolerability of preservative-free fixed combination of tafluprost 0.0015%/timolol 0.5% versus concomitant use of the ingredients.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F; Timolol; Young Adult | 2014 |
Effect of early treatment with aqueous suppressants on Ahmed glaucoma valve implantation outcomes.
Topics: Adult; Antihypertensive Agents; Aqueous Humor; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Logistic Models; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2014 |
Trans-conjunctival aqueous humor outflow in glaucomatous patients treated with prostaglandin analogues: an in vivo confocal microscopy study.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Cell Count; Conjunctiva; Cysts; Double-Blind Method; Epithelial Cells; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Microscopy, Confocal; Middle Aged; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Visual Acuity | 2014 |
24-hour efficacy of travoprost/timolol BAK-free versus latanoprost/timolol fixed combinations in patients insufficiently controlled with latanoprost.
Topics: Antihypertensive Agents; Cross-Over Studies; Drug Combinations; Drug Monitoring; Drug Synergism; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2014 |
Long term IOP lowering efficacy of bimatoprost/timolol fixed combination: a 12 month prospective study.
Topics: Aged; Amides; Bimatoprost; Cloprostenol; Drug Combinations; Female; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Timolol; Treatment Outcome | 2013 |
Effect of topical aqueous suppression on intraocular gas duration after pure perfluoropropane injection in nonvitrectomized eyes with retinal detachment.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cryotherapy; Drug Combinations; Endotamponade; Fluorocarbons; Humans; Injections, Intraocular; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Prospective Studies; Retinal Detachment; Scleral Buckling; Sulfonamides; Thiophenes; Time Factors; Timolol; Vitrectomy | 2014 |
Efficacy and tolerability of fixed-combination brinzolamide/timolol in Latin American patients with open-angle glaucoma or ocular hypertension previously on brimonidine/timolol fixed combination.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latin America; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Research Design; Sulfonamides; Thiazines; Timolol; United States | 2014 |
The Efficacy of a Latanoprost/Timolol Fixed Combination Versus Latanoprost and Timolol Gel-forming Solution Unfixed Combination on Daytime Intraocular Pressure.
Topics: Aged; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome | 2016 |
Comparing the efficacy of latanoprost (0.005%), bimatoprost (0.03%), travoprost (0.004%), and timolol (0.5%) in the treatment of primary open angle glaucoma.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Blood Pressure; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Visual Acuity; Visual Field Tests; Visual Fields | 2014 |
A 6-month study comparing efficacy, safety, and tolerability of the preservative-free fixed combination of tafluprost 0.0015% and timolol 0.5% versus each of its individual preservative-free components.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Effect of topical ophthalmic dorzolamide(2%)-timolol(0.5%) solution and ointment on intraocular pressure in normal horses.
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Animals; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Ointments; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Efficacy and tolerability of fixed-combination bimatoprost/timolol versus fixed-combination dorzolamide/brimonidine/timolol in patients with primary open-angle glaucoma or ocular hypertension: a multicenter, prospective, crossover study.
Topics: Administration, Topical; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2014 |
Comparison of the effects of bimatoprost and a fixed combination of latanoprost and timolol on 24-hour blood and ocular perfusion pressures: the results of a randomized trial.
Topics: Adult; Aged; Amides; Analysis of Variance; Antihypertensive Agents; Bimatoprost; Blood Pressure; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2015 |
Short-term effect of topical brinzolamide 1%-timolol 0.5% fixed combination on human central corneal thickness.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Capsule Opacification; Carbonic Anhydrase Inhibitors; Clonidine; Cornea; Corneal Pachymetry; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lasers, Solid-State; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2015 |
Effects of Switching from Timolol to Brimonidine in Prostaglandin Analog and Timolol Combination Therapy.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins, Synthetic; Timolol; Treatment Outcome | 2015 |
Effect of glaucoma medications on 24-hour intraocular pressure-related patterns using a contact lens sensor.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Circadian Rhythm; Contact Lenses; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Monitoring, Ambulatory; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Young Adult | 2015 |
Oxygen therapy for corneal edema after cataract surgery.
Topics: Adrenergic beta-Antagonists; Aged; Betamethasone; Corneal Edema; Corneal Pachymetry; Endothelium, Corneal; Female; Glucocorticoids; Humans; Intraocular Pressure; Isotonic Solutions; Male; Middle Aged; Oxygen; Phacoemulsification; Sodium Chloride; Timolol; Visual Acuity | 2015 |
Anterior segment morphology after acute primary angle closure treatment: a randomised study comparing iridoplasty and medical therapy.
Topics: Acute Disease; Aged; Anterior Eye Segment; Antihypertensive Agents; Argon Plasma Coagulation; Brimonidine Tartrate; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Intraocular Pressure; Iridectomy; Iris; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Prospective Studies; Tertiary Care Centers; Timolol; Tomography, Optical Coherence; Tonometry, Ocular | 2016 |
Fixed Combination of Travoprost and Timolol Maleate Reduces Intraocular Pressure in Japanese Patients with Primary Open-Angle Glaucoma or Ocular Hypertension: A Prospective Multicenter Open-Label Study.
Topics: Adult; Aged; Aged, 80 and over; Cloprostenol; Drug Combinations; Drug Substitution; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Japan; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol; Tonometry, Ocular | 2015 |
Effects of Topical Bimatoprost 0.01% and Timolol 0.5% on Circadian IOP, Blood Pressure and Perfusion Pressure in Patients with Glaucoma or Ocular Hypertension: A Randomized, Double Masked, Placebo-Controlled Clinical Trial.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Bimatoprost; Blood Pressure; Circadian Rhythm; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol; Tonometry, Ocular; Treatment Outcome | 2015 |
Comparison of the intraocular pressure-lowering effect and safety of brimonidine/timolol fixed combination and 0.5% timolol in normal-tension glaucoma patients.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Brimonidine Tartrate; Corneal Pachymetry; Drug Combinations; Female; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol; Tonometry, Ocular | 2016 |
Comparison of the Effects of Dorzolamide/Timolol Fixed Combination versus Latanoprost on Intraocular Pressure and Ocular Perfusion Pressure in Patients with Normal-Tension Glaucoma: A Randomized, Crossover Clinical Trial.
Topics: Blood Pressure; Circadian Rhythm; Cross-Over Studies; Demography; Diastole; Drug Combinations; Female; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Low Tension Glaucoma; Male; Middle Aged; Perfusion; Prostaglandins F, Synthetic; Sulfonamides; Systole; Thiophenes; Timolol | 2016 |
Latanoprostene Bunod 0.024% versus Timolol Maleate 0.5% in Subjects with Open-Angle Glaucoma or Ocular Hypertension: The APOLLO Study.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Young Adult | 2016 |
Effect of timolol maleate gel-forming solution on intraocular pressure, pupil diameter, and heart rate in normal and glaucomatous cats.
Topics: Adrenergic beta-Antagonists; Animals; Cat Diseases; Cats; Female; Glaucoma; Heart Rate; Intraocular Pressure; Male; Ophthalmic Solutions; Pupil; Timolol | 2016 |
Brinzolamide/timolol versus dorzolamide/timolol fixed combinations: A hospital-based, prospective, randomized study.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Egypt; Female; Glaucoma, Open-Angle; Hospitals, University; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular | 2016 |
Six-Month Intraocular Pressure Reduction with a Topical Bimatoprost Ocular Insert: Results of a Phase II Randomized Controlled Study.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Bimatoprost; Delayed-Action Preparations; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol; Tonometry, Ocular | 2016 |
Comparison of Latanoprostene Bunod 0.024% and Timolol Maleate 0.5% in Open-Angle Glaucoma or Ocular Hypertension: The LUNAR Study.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Antihypertensive Agents; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Visual Acuity; Young Adult | 2016 |
Preservative-free tafluprost in the treatment of open-angle glaucoma or ocular hypertension in India: a phase III clinical trial.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; India; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prostaglandins F; Prostaglandins, Synthetic; Timolol | 2016 |
Effects of a dorzolamide/timolol fixed combination on diurnal intraocular pressure, heart rate, blood pressure, and ocular perfusion pressure in normal-tension glaucoma.
Topics: Aged; Blood Pressure; Circadian Rhythm; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Gonioscopy; Heart Rate; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Time Factors; Timolol | 2016 |
Comparison of dorzolamide/timolol vs brinzolamide/brimonidine fixed combination therapy in the management of primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Efficacy of Latanoprostene Bunod 0.024% Compared With Timolol 0.5% in Lowering Intraocular Pressure Over 24 Hours.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 2016 |
Preventive Dorzolamide-Timolol for Rising Intraocular Pressure During Steep Trendelenburg Position Surgery.
Topics: Adult; Aged; Blood Pressure; Double-Blind Method; Drug Combinations; Eye; Female; Head-Down Tilt; Humans; Intraocular Pressure; Intraoperative Complications; Laparoscopy; Male; Middle Aged; Monitoring, Intraoperative; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2016 |
24-Hour Efficacy and Ocular Surface Health with Preservative-Free Tafluprost Alone and in Conjunction with Preservative-Free Dorzolamide/Timolol Fixed Combination in Open-Angle Glaucoma Patients Insufficiently Controlled with Preserved Latanoprost Monothe
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins F; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Adherence to Fixed-Combination Versus Unfixed Travoprost 0.004%/Timolol 0.5% for Glaucoma or Ocular Hypertension: A Randomized Trial.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Compliance; Single-Blind Method; Time Factors; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2017 |
The 24-Hour Effects of Brinzolamide/Brimonidine Fixed Combination and Timolol on Intraocular Pressure and Ocular Perfusion Pressure.
Topics: Aged; Blood Pressure; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol | 2017 |
Efficacy and safety of preoperative IOP reduction using a preservative-free fixed combination of dorzolamide/timolol eye drops versus oral acetazolamide and dexamethasone eye drops and assessment of the clinical outcome of trabeculectomy in glaucoma.
Topics: Acetazolamide; Aged; Antihypertensive Agents; Dexamethasone; Drug Combinations; Female; Fluorouracil; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preoperative Care; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Treatment Outcome | 2017 |
Bimatoprost/timolol fixed combination vs latanoprost/timolol fixed combination in open-angle glaucoma patients.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Timolol | 2009 |
Intraocular pressure-lowering efficacy of brinzolamide 1%/timolol 0.5% fixed combination compared with brinzolamide 1% and timolol 0.5%.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Visual Acuity | 2008 |
Long-term efficacy and safety of bimatoprost for intraocular pressure lowering in glaucoma and ocular hypertension: year 4.
Topics: Amides; Analysis of Variance; Bimatoprost; Cloprostenol; Conjunctival Diseases; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Treatment Outcome; Visual Acuity | 2008 |
24-hour control of intraocular pressure with 2% dorzolamide/0.5% timolol fixed-combination ophthalmic solution in open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2008 |
Effects of dorzolamide 2% added to timolol maleate 0.5% on intraocular pressure, retrobulbar blood flow, and the progression of visual field damage in patients with primary open-angle glaucoma: a single-center, 4-year, open-label study.
Topics: Aged; Antihypertensive Agents; Disease Progression; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Orbit; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Fields | 2008 |
Changes in visual function after intraocular pressure reduction using antiglaucoma medications.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cloprostenol; Contrast Sensitivity; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Timolol; Travoprost; Visual Acuity; Visual Fields; Visual Perception | 2009 |
Prolongation of activity of single intravitreal bevacizumab by adjuvant topical aqueous depressant (Timolol-Dorzolamide).
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Aqueous Humor; Bevacizumab; Diabetic Retinopathy; Drug Synergism; Drug Therapy, Combination; Female; Humans; Injections; Intraocular Pressure; Macular Edema; Male; Middle Aged; Retinal Vein Occlusion; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity; Vitreous Body | 2009 |
Second-line therapy with dorzolamide/timolol or latanoprost/timolol fixed combination versus adding dorzolamide/timolol fixed combination to latanoprost monotherapy.
Topics: Antihypertensive Agents; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
Efficacy and safety of latanoprost versus pilocarpine/timolol maleate fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Pain; Pilocarpine; Prostaglandins F, Synthetic; Timolol; Treatment Outcome; Vision Disorders | 2008 |
[Comparison of intraocular pressure lowering efficacy of bimatoprost / timolol fixed combination and other glaucoma medications in the treatment of glaucoma].
Topics: Adult; Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypotension; Prostaglandins F, Synthetic; Timolol; Travoprost | 2008 |
Intraocular pressure control with latanoprost/timolol and travoprost/timolol fixed combinations : a retrospective, multicentre, cross-sectional study.
Topics: Adult; Aged; Cloprostenol; Cross-Sectional Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Timolol; Travoprost | 2008 |
Twenty-four-hour intraocular pressure control with the travoprost/timolol maleate fixed combination compared with travoprost when both are dosed in the evening in primary open-angle glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Timolol; Travoprost; Treatment Outcome | 2009 |
A one-week comfort study of BID-dosed brinzolamide 1%/timolol 0.5% ophthalmic suspension fixed combination compared to BID-dosed dorzolamide 2%/timolol 0.5% ophthalmic solution in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2008 |
Changes in optic nerve head blood flow induced by the combined therapy of latanoprost and beta blockers.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Blood Flow Velocity; Blood Pressure; Carteolol; Ciliary Arteries; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Latanoprost; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Artery; Ophthalmic Solutions; Optic Disk; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Artery; Timolol; Tonometry, Ocular | 2009 |
An eight-week, multicentric, randomized, interventional, open-label, phase 4, parallel comparison of the efficacy and tolerability of the fixed combination of timolol maleate 0.5%/brimonidine tartrate 0.2% versus fixed combination of timolol maleate 0.5%/
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Young Adult | 2008 |
Comparing diurnal and nocturnal effects of brinzolamide and timolol on intraocular pressure in patients receiving latanoprost monotherapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular | 2009 |
Intraocular pressure control over 24 hours using travoprost and timolol fixed combination administered in the morning or evening in primary open-angle and exfoliative glaucoma.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol; Tonometry, Ocular; Travoprost; Visual Acuity | 2009 |
Efficacy and safety of latanoprost in eyes with uveitic glaucoma.
Topics: Adult; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Uveitis, Anterior; Uveitis, Intermediate; Visual Acuity | 2009 |
Pneumatic trabeculoplasty vs latanoprost as adjunctive therapy to timolol in primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Trabeculectomy; Treatment Outcome; Visual Acuity | 2009 |
A comparison of the long-term effects of dorzolamide 2% and brinzolamide 1%, each added to timolol 0.5%, on retrobulbar hemodynamics and intraocular pressure in open-angle glaucoma patients.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Regional Blood Flow; Sulfonamides; Thiazines; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2009 |
[Analysis of the effectiveness of beta-blockers for intraocular pressure and visual field in primary open-angle glaucoma].
Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Retrospective Studies; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Field Tests; Visual Fields | 2008 |
24-hour intraocular pressure and blood pressure levels with latanoprost/timolol fixed combination versus timolol.
Topics: Aged; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2009 |
Dorzolamide-timolol combination and retinal vessel oxygen saturation in patients with glaucoma or ocular hypertension.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Oximetry; Oxygen; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Young Adult | 2009 |
Three-month, randomized, parallel-group comparison of brimonidine-timolol versus dorzolamide-timolol fixed-combination therapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Osmolar Concentration; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Switching from concomitant latanoprost 0.005% and timolol 0.5% to a fixed combination of travoprost 0.004%/timolol 0.5% in patients with primary open-angle glaucoma and ocular hypertension: a 6-month, multicenter, cohort study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Cohort Studies; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Tears; Time Factors; Timolol; Travoprost | 2009 |
The effect of travoprost 0.004% as an adjuvant to timolol 0.5% therapy.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Timolol; Travoprost | 2009 |
Comparison of effects of topical levobunolol to a combination of timolol-dorzolamide on intraocular pressure and pulse rate of healthy dogs.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Dogs; Drug Combinations; Female; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol | 2009 |
Betaxolol hydrochloride ophthalmic suspension 0.25% and timolol gel-forming solution 0.25% and 0.5% in pediatric glaucoma: a randomized clinical trial.
Topics: Antihypertensive Agents; Betaxolol; Child; Child, Preschool; Double-Blind Method; Female; Gels; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular Pressure; Male; Ophthalmic Solutions; Suspensions; Timolol; Tonometry, Ocular; Visual Acuity | 2009 |
Using diurnal intraocular pressure fluctuation to assess the efficacy of fixed-combination latanoprost/timolol versus latanoprost or timolol monotherapy.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2010 |
Ocular blood flow and oxygen delivery to the retina in primary open-angle glaucoma patients: the addition of dorzolamide to timolol monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Middle Aged; Oximetry; Oxygen; Regional Blood Flow; Retina; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2010 |
Predictors for visual field progression and the effects of treatment with dorzolamide 2% or brinzolamide 1% each added to timolol 0.5% in primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Carbonic Anhydrase Inhibitors; Ciliary Arteries; Disease Progression; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Proportional Hazards Models; Prospective Studies; Retinal Artery; Risk Factors; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler, Color; Vision Disorders; Visual Fields | 2010 |
Twenty-four-hour intraocular pressure control with bimatoprost and the bimatoprost/timolol fixed combination administered in the morning, or evening in exfoliative glaucoma.
Topics: Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Single-Blind Method; Timolol; Treatment Outcome | 2010 |
Effect of dorzolamide and timolol on ocular pressure: blood flow relationship in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Interferometry; Intraocular Pressure; Laser-Doppler Flowmetry; Lasers; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Nerve Diseases; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2010 |
The safety and efficacy of bimatoprost/timolol fixed combination: a 1-year double-masked, randomized parallel comparison to its individual components in patients with glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
A comparison of bimatoprost 0.03% versus the fixed-combination of latanoprost 0.005% and timolol 0.5% in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label trial.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Blood Pressure; Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2009 |
The ability of short-wavelength automated perimetry to predict conversion to glaucoma.
Topics: Aged; Antihypertensive Agents; Betaxolol; Double-Blind Method; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Nerve Fibers; Ocular Hypertension; Optic Nerve Diseases; Prospective Studies; Retinal Ganglion Cells; Timolol; Vision Disorders; Visual Field Tests; Visual Fields | 2010 |
Short-term tolerability of once-daily timolol hemihydrate 0.5%, timolol maleate in sorbate 0.5%, and generic timolol maleate gel-forming solution 0.5% in glaucoma and/or ocular hypertension: a prospective, randomized, double-masked, active-controlled, thr
Topics: Adrenergic beta-Antagonists; Aged; Anterior Chamber; Cross-Over Studies; Double-Blind Method; Drugs, Generic; Female; Gels; Glaucoma; Humans; Intraocular Pressure; Irritants; Male; Ocular Hypertension; Pharmaceutical Solutions; Prospective Studies; Therapeutic Equivalency; Timolol; Vision Disorders; Visual Acuity | 2009 |
Efficacy and safety of fixed combinations of latanoprost/timolol and dorzolamide/timolol in open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2010 |
Fixed-combination brimonidine/timolol as adjunctive therapy to a prostaglandin analog: a 3-month, open-label, replacement study in glaucoma patients.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Hypersensitivity; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2009 |
Comparative study of topical application of timolol and verapamil in patients with glaucoma within 6 months.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol; Tonometry, Ocular; Treatment Outcome; Verapamil | 2009 |
Fixed combination of latanoprost and timolol vs individual components for primary open-angle glaucoma or ocular hypertension: a randomized, double-masked study.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2010 |
Efficacy and mechanisms of intraocular pressure reduction with latanoprost and timolol in participants with ocular hypertension: a comparison of 1 and 6 weeks of treatment.
Topics: Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sclera; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome; Uvea | 2010 |
Predictors of additional intraocular pressure reduction in patients changed to latanoprost/timolol fixed combination.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prognosis; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome; Young Adult | 2010 |
Effect of brimonidine/timolol fixed combination on preventing the short-term intraocular pressure increase after intravitreal injection of ranibizumab.
Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Humans; Injections, Intralesional; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Placebo Effect; Quinoxalines; Ranibizumab; Timolol; Treatment Outcome; Vitreous Body | 2010 |
Comparison of ocular hypotensive actions of fixed combinations of brimonidine/timolol and dorzolamide/timolol.
Topics: Aged; Aged, 80 and over; Algorithms; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dosage Forms; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2010 |
Comparison of the efficacy and tolerability of preservative-free and preservative-containing formulations of the dorzolamide/timolol fixed combination (COSOPT™) in patients with elevated intraocular pressure in a randomized clinical trial.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
The combination latanoprost-timolol versus twice daily 0.50% timolol administration either associated or not with latanoprost: efficacy and tolerability in the primary open-angle glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Time Factors; Timolol; Treatment Outcome | 2010 |
24-h Intraocular pressure control with evening-dosed travoprost/timolol, compared with latanoprost/timolol, fixed combinations in exfoliative glaucoma.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Time Factors; Timolol; Travoprost | 2010 |
Comparison of the effects of dorzolamide/timolol and latanoprost/timolol fixed combinations upon intraocular pressure and progression of visual field damage in primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Disease Progression; Dosage Forms; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Fields | 2010 |
Comparison of Travoprost and Bimatoprost plus timolol fixed combinations in open-angle glaucoma patients previously treated with latanoprost plus timolol fixed combination.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Cross-Over Studies; Double-Blind Method; Drug Combinations; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Travoprost; Visual Acuity | 2010 |
Visual field loss in patients with normal-tension glaucoma under topical nipradilol or timolol: subgroup and subfield analyses of the nipradilol-timolol study.
Topics: Administration, Topical; Adult; Antihypertensive Agents; Disease Progression; Double-Blind Method; Female; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol; Treatment Outcome; Vision Disorders; Visual Field Tests; Visual Fields | 2010 |
Effects of topical 0.5% levobunolol alone or in association with 2% dorzolamide compared with a fixed combination of 0.5% timolol and 2% dorzolamide on intraocular pressure and heart rate in dogs without glaucoma.
Topics: Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Dogs; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Heart Rate; Intraocular Pressure; Levobunolol; Male; Sulfonamides; Thiophenes; Timolol | 2010 |
Intraocular pressure-lowering efficacy of brinzolamide when added to travoprost/timolol fixed combination as adjunctive therapy.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Visual Acuity | 2012 |
Twenty-four-hour intraocular pressure control with latanoprost-timolol-fixed combination versus bimatoprost in patients who switched from timolol.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome; Vision Disorders; Visual Fields | 2011 |
Control of intraocular pressure and fluctuation with fixed-combination brimonidine-timolol versus brimonidine or timolol monotherapy.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Double-Blind Method; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Timolol; Tonometry, Ocular | 2011 |
Observational study of patients switched to the fixed travoprost 0.004%/timolol 0.5% combination in Croatia.
Topics: Antihypertensive Agents; Cloprostenol; Croatia; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Timolol; Travoprost; Treatment Outcome | 2010 |
Effect of a fixed brimonidine-timolol combination on intraocular pressure after phacoemulsification.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Cataract Extraction; Double-Blind Method; Drug Combinations; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Prospective Studies; Quinoxalines; Time Factors; Timolol | 2011 |
A randomized trial of brimonidine versus timolol in preserving visual function: results from the Low-Pressure Glaucoma Treatment Study.
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Brimonidine Tartrate; Double-Blind Method; Female; Follow-Up Studies; Gonioscopy; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Quinoxalines; Timolol; Tonometry, Ocular; Treatment Outcome; Vision Disorders; Visual Acuity; Visual Fields | 2011 |
Intraocular pressure changes in the contralateral eye after topical treatment: does an "ophthalmotonic consensual reaction" exist?
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Timolol | 2010 |
[Effect on ocular blood flow of Combigan® versus placebo in patients with ocular hypertension].
Topics: Aged; Brimonidine Tartrate, Timolol Maleate Drug Combination; Double-Blind Method; Drug Combinations; Female; Follow-Up Studies; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Regional Blood Flow; Retinal Vessels; Timolol; Ultrasonography, Doppler, Color; Vascular Resistance | 2011 |
Timolol versus brinzolamide added to travoprost in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2011 |
[Comparative study of the pressure lowering efficacy and variations in the ocular pulse amplitude between fixed combinations of dorzolamide/timolol and brinzolamide/timolol].
Topics: Adult; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Pulse; Sulfonamides; Thiazines; Thiophenes; Timolol; Young Adult | 2011 |
From dorzolamide 2%/timolol 0.5% to brinzolamide 1%/timolol 0.5% fixed combination: a 6-month, multicenter, open-label tolerability switch study.
Topics: Aged; Antihypertensive Agents; Diagnostic Techniques, Ophthalmological; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiazines; Thiophenes; Timolol | 2011 |
Comparison of latanoprost and timolol in pediatric glaucoma: a phase 3, 12-week, randomized, double-masked multicenter study.
Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Double-Blind Method; Female; Glaucoma; Humans; Hydrophthalmos; Infant; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2011 |
Travoprost 0.004%/timolol 0.5%-fixed combination with and without benzalkonium chloride: a prospective, randomized, doubled-masked comparison of safety and efficacy.
Topics: Aged; Antihypertensive Agents; Benzalkonium Compounds; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Japan; Logistic Models; Male; Middle Aged; Ocular Hypertension; Polymers; Prospective Studies; Timolol; Travoprost; United States | 2011 |
Ocular hypotensive effect of oral palmitoyl-ethanolamide: a clinical trial.
Topics: Administration, Oral; Aged; Amides; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Endocannabinoids; Ethanolamines; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Palmitic Acids; Prospective Studies; Tablets; Timolol; Visual Acuity; Visual Fields | 2011 |
24-Hour intraocular pressure control between travoprost/timolol fixed combination, latanoprost/ timolol fixed combination and standard timolol in primary open angle glaucoma and ocular hypertension.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Time Factors; Timolol; Travoprost; Treatment Outcome; Young Adult | 2011 |
[Double-masked, phase III comparative study of the combination ophthalmic solution of the 1% dorzolamide hydrochloride/0.5% timolol maleate (MK-0507A) in patients with glaucoma and ocular hypertension].
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2011 |
Pharmacodynamic equivalence study of two preparations of eye drops containing dorzolamide and timolol in healthy volunteers.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Eye Movements; Female; Fundus Oculi; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pupil; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Visual Acuity; Young Adult | 2011 |
Travoprost 0.004%/timolol 0.5% fixed combination in patients transitioning from fixed or unfixed bimatoprost 0.03%/timolol 0.5%.
Topics: Adult; Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol; Travoprost | 2011 |
Diurnal intraocular pressure efficacy of the timolol-brimonidine fixed combination and the timolol-dorzolamide fixed combination as a first choice therapy in patients with pseudoexfoliation glaucoma.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Single-Blind Method; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome; Visual Acuity | 2011 |
Comparative efficacy and safety of the fixed versus unfixed combination of latanoprost and timolol in Chinese patients with open-angle glaucoma or ocular hypertension.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; China; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prevalence; Prostaglandins F, Synthetic; Retrospective Studies; Time Factors; Timolol; Treatment Outcome; Young Adult | 2011 |
Twenty-four hour efficacy with the dorzolamide/timolol-fixed combination compared with the brimonidine/timolol-fixed combination in primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2012 |
Ocular hypotensive effects and safety over 3 months of switching from an unfixed combination to latanoprost 0.005%/timolol maleate 0.5% fixed combination.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Surveys and Questionnaires; Timolol; Tonometry, Ocular; Treatment Outcome | 2011 |
Circadian intraocular pressure and blood pressure reduction with timolol 0.5% solution and timogel 0.1% in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Administration Schedule; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Timolol | 2012 |
Comparison of fixed combinations of dorzolamide/timolol and brimonidine/timolol in patients with primary open-angle glaucoma.
Topics: Aged; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Patient Compliance; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2011 |
Short-term effects of brimonidine/timolol and dorzolamide/timolol on ocular perfusion pressure and blood flow in glaucoma.
Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
Efficacy of single glaucoma drug in combined timolol XE, latanoprost and brinzolamide therapy: a discontinuation study.
Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol | 2012 |
Randomized clinical trial of the efficacy and safety of preservative-free tafluprost and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2012 |
Comparison of dorzolamide/timolol and latanoprost/timolol fixed combinations on diurnal intraocular pressure control in primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Optic Disk; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2012 |
Diurnal and nocturnal variations in aqueous humor dynamics of patients with ocular hypertension undergoing medical therapy.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aqueous Humor; Blood Pressure; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Cornea; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sphygmomanometers; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography | 2012 |
Efficacy of single glaucoma medication in combined latanoprost and timolol XE therapy in patients with open-angle glaucoma and ocular hypertension: a discontinuation study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sample Size; Substance Withdrawal Syndrome; Timolol; Treatment Outcome | 2012 |
Fixed-combination brimonidine-timolol versus latanoprost in glaucoma and ocular hypertension: a 12-week, randomized, comparison study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Time Factors; Timolol; Treatment Outcome | 2012 |
Benzalkonium chloride induces anterior chamber inflammation in previously untreated patients with ocular hypertension as measured by flare meter: a randomized clinical trial.
Topics: Adult; Aged; Antihypertensive Agents; Aqueous Humor; Benzalkonium Compounds; Blood-Aqueous Barrier; Diagnostic Techniques, Ophthalmological; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Single-Blind Method; Timolol; Uveitis, Anterior | 2012 |
Risk factors for progression of normal-tension glaucoma under β-blocker monotherapy.
Topics: Adrenergic beta-Antagonists; Disease Progression; Double-Blind Method; Female; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Myopia; Ophthalmic Solutions; Prognosis; Propanolamines; Prospective Studies; Risk Factors; Timolol; Tonometry, Ocular; Vision Disorders; Visual Fields | 2012 |
A study of initial therapy for glaucoma in southern India: India Glaucoma Outcomes and Treatment (INGOT) Study.
Topics: Aged; Antihypertensive Agents; Antimetabolites, Antineoplastic; Brimonidine Tartrate; Drug Combinations; Female; Fluorouracil; Glaucoma; Humans; India; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular; Trabeculectomy; Visual Acuity | 2012 |
Intraocular pressure-reducing effects of latanoprost versus timolol in chinese patients with chronic angle-closure glaucoma.
Topics: Adolescent; Adult; Aged; Antihypertensive Agents; Asian People; China; Chronic Disease; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Timolol; Treatment Outcome; Young Adult | 2013 |
A double-masked randomized crossover study comparing the effect of latanoprost/timolol and brimonidine/timolol fixed combination on intraocular pressure and ocular blood flow in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Time Factors; Timolol; Ultrasonography, Doppler, Color | 2012 |
Fixed combination brimonidine-timolol versus brimonidine for treatment of intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Capsule Opacification; Drug Combinations; Female; Follow-Up Studies; Humans; Intraocular Pressure; Lasers, Solid-State; Male; Middle Aged; Phacoemulsification; Preoperative Care; Quinoxalines; Timolol; Treatment Outcome | 2012 |
[Efficacy of prophylactic treatment of intraocular pressure spikes due to intravitreal injections].
Topics: Acetazolamide; Aged; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Brimonidine Tartrate; Chemoprevention; Clonidine; Drug Combinations; Female; Humans; Hypotonic Solutions; Intraocular Pressure; Intravitreal Injections; Macular Degeneration; Male; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2012 |
Risk factors for visual field progression in the low-pressure glaucoma treatment study.
Topics: Administration, Topical; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Aged; Brimonidine Tartrate; Disease Progression; Double-Blind Method; Female; Follow-Up Studies; Gonioscopy; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Risk Factors; Timolol; Vision Disorders; Visual Acuity; Visual Field Tests; Visual Fields | 2012 |
Effect of timolol on refractive outcomes in eyes with myopic regression after laser in situ keratomileusis: a prospective randomized clinical trial.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Female; Humans; Intraocular Pressure; Keratomileusis, Laser In Situ; Lasers, Excimer; Male; Middle Aged; Myopia; Ophthalmic Solutions; Prospective Studies; Refraction, Ocular; Timolol; Visual Acuity; Young Adult | 2012 |
Three-month evaluation of dorzolamide hydrochloride/timolol maleate fixed-combination eye drops versus the separate use of both drugs.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
Adherence improvement in Dutch glaucoma patients: a randomized controlled trial.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Drug Combinations; Drug Monitoring; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Medication Adherence; Middle Aged; Netherlands; Ocular Hypertension; Ophthalmic Solutions; Patient Compliance; Patient Education as Topic; Surveys and Questionnaires; Timolol; Tonometry, Ocular; Travoprost | 2013 |
[Phase III clinical trial of brimonidine in patients with primary open-angle glaucoma and ocular hypertension--comparison of the effects of brimonidine monotherapy versus timolol monotherapy, or combination brimonidine/prostaglandins therapy versus combin
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins; Quinoxalines; Timolol; Treatment Outcome | 2012 |
The effect of latanoprost compared with timolol in African-American, Asian, Caucasian, and Mexican open-angle glaucoma or ocular hypertensive patients.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Asia; Black People; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Mexico; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; White People | 2002 |
Efficacy of latanoprost in reducing intraocular pressure in patients with primary angle-closure glaucoma.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Double-Blind Method; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Safety; Timolol | 2002 |
One-year, randomized study comparing bimatoprost and timolol in glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Amides; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Humans; Hyperemia; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Safety; Timolol; Treatment Outcome | 2002 |
Comparison of latanoprost, brimonidine and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2002 |
Progression of retinal nerve fibre layer damage in betaxolol- and timolol-treated glaucoma patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Disease Progression; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Nerve Fibers; Optic Nerve Diseases; Photography; Prospective Studies; Retinal Ganglion Cells; Timolol | 2002 |
The safety and efficacy of timolol 0.5% in xanthan gum versus timolol gel forming solution 0.5%.
Topics: Adrenergic beta-Antagonists; Adult; Anterior Eye Segment; Conjunctiva; Gels; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Ocular Hypertension; Polysaccharides, Bacterial; Prospective Studies; Safety; Single-Blind Method; Solutions; Staining and Labeling; Timolol; Visual Acuity | 2002 |
A comparison of the effects on intraocular pressure of latanoprost 0.005% and the fixed combination of dorzolamide 2% and timolol 0.5% in patients with open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2002 |
A comparison of the fixed combination of latanoprost and timolol with its individual components.
Topics: Aged; Circadian Rhythm; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 2002 |
A randomised, double masked, multicentre clinical trial comparing bimatoprost and timolol for the treatment of glaucoma and ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Timolol; Treatment Outcome | 2003 |
A prospective, long-term, randomized study of the efficacy and safety of the drug combination pilocarpine 1% with clonidine 0.06% or clonidine 0.125% versus timolol 0.25%.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Drug Administration Schedule; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Muscarinic Agonists; Pilocarpine; Safety; Timolol; Treatment Outcome | 2002 |
Projected impact of travoprost versus both timolol and latanoprost on visual field deficit progression and costs among black glaucoma subjects.
Topics: Aged; Antihypertensive Agents; Black People; Cloprostenol; Disease Progression; Double-Blind Method; Drug Costs; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Travoprost; United States; Vision Disorders; Visual Fields | 2002 |
Timolol 0.5%/dorzolamide 2% fixed combination vs timolol maleate 0.5% and unoprostone 0.15% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome; Visual Acuity | 2003 |
The efficacy and safety of the timolol/dorzolamide fixed combination vs latanoprost in exfoliation glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Patient Satisfaction; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2003 |
Dorzolamide/timolol combination versus concomitant administration of brimonidine and timolol: six-month comparison of efficacy and tolerability.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 2003 |
The effect of latanoprost, brimonidine, and a fixed combination of timolol and dorzolamide on circadian intraocular pressure in patients with glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2003 |
Unoprostone as adjunctive therapy to timolol: a double masked randomised study versus brimonidine and dorzolamide.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chemotherapy, Adjuvant; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2003 |
Efficacy and safety of timolol maleate/latanoprost fixed combination versus timolol maleate and brimonidine given twice daily.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Safety; Timolol | 2003 |
Effect of changing from concomitant timolol pilocarpine to bimatoprost monotherapy on ocular blood flow and IOP in primary chronic angle closure glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Amides; Bimatoprost; Chronic Disease; Cloprostenol; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Pilocarpine; Prospective Studies; Pulsatile Flow; Regional Blood Flow; Single-Blind Method; Timolol; Treatment Outcome | 2003 |
Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Aqueous humour flow after a single oral dose of isosorbide-5-mononitrate in healthy volunteers.
Topics: Administration, Oral; Adult; Aqueous Humor; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Fluorophotometry; Humans; Intraocular Pressure; Isosorbide Dinitrate; Male; Nitric Oxide Donors; Timolol; Tonometry, Ocular | 2003 |
Twenty-four-hour diurnal curve comparison of commercially available latanoprost 0.005% versus the timolol and dorzolamide fixed combination.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Peak pressures: crossover study of timolol and latanoprost.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2003 |
Evaluation of retinal haemodynamics and retinal function after application of dorzolamide, timolol and latanoprost in newly diagnosed open-angle glaucoma patients.
Topics: Adrenergic beta-Antagonists; Arteries; Blood Pressure; Carbonic Anhydrase Inhibitors; Contrast Sensitivity; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Microscopy, Confocal; Middle Aged; Ophthalmoscopy; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Vessels; Sulfonamides; Thiophenes; Timolol; Veins | 2003 |
Effect of a fixed dorzolamide-timolol combination on intraocular pressure after small-incision cataract surgery with Viscoat.
Topics: Aged; Aged, 80 and over; Cataract Extraction; Chondroitin; Chondroitin Sulfates; Double-Blind Method; Drug Combinations; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Time Factors; Timolol | 2003 |
A six-week, parallel, randomized, double-blind study comparing the efficacy and safety of the 0.5% timolol/2.0% MK-507 combination b.i.d. to the concomitant administration of 0.5% timolol b.i.d. and 2.0% MK-507 b.i.d.
Topics: Adult; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Sulfonamides; Thiophenes; Timolol | 2003 |
A 3-month randomized controlled trial of bimatoprost (LUMIGAN) versus combined timolol and dorzolamide (Cosopt) in patients with glaucoma or ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol | 2003 |
Pooled-data analysis of three randomized, double-masked, six-month studies comparing intraocular pressure-reducing effects of latanoprost and timolol in patients with ocular hypertension.
Topics: Antihypertensive Agents; Double-Blind Method; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Retrospective Studies; Timolol; Treatment Outcome | 2003 |
Rate of response to latanoprost or timolol in patients with ocular hypertension or glaucoma.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Drug Resistance; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2003 |
Contrast sensitivity improves after brimonidine therapy in primary open angle glaucoma: a case for neuroprotection.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Brimonidine Tartrate; Contrast Sensitivity; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Quinoxalines; Receptors, Adrenergic, alpha-2; Timolol | 2003 |
Efficacy of bunazosin hydrochloride 0.01% as adjunctive therapy of latanoprost or timolol.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Pupil; Quinazolines; Timolol | 2004 |
A 12 week study comparing the fixed combination of latanoprost and timolol with the concomitant use of the individual components in patients with open angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2004 |
A study of replacement of timolol-pilocarpine with latanoprost in pseudoexfoliation glaucoma.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Pilocarpine; Prostaglandins F, Synthetic; Timolol | 2003 |
Crossover comparison of timolol and latanoprost in chronic primary angle-closure glaucoma.
Topics: Aged; Antihypertensive Agents; Chronic Disease; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iridectomy; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol | 2004 |
[Long-term efficacy and safety of combined topical antiglaucoma therapy--timolol & unoprostone vs. betaxolol & unoprostone].
Topics: Adult; Aged; Antihypertensive Agents; Betaxolol; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol; Visual Fields | 2004 |
Efficacy and tolerability of the dorzolamide 2%/timolol 0.5% combination (COSOPT) versus 0.005% (XALATAN) in the treatment of ocular hypertension or glaucoma: results from two randomized clinical trials.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Diurnal intraocular pressure reduction with latanoprost 0.005% compared to timolol maleate 0.5% as monotherapy in subjects with exfoliation glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Timolol | 2004 |
24-Hour IOP control with once-daily bimatoprost, timolol gel-forming solution, or latanoprost: a 1-month, randomized, comparative clinical trial.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2004 |
Two-year double-masked comparison of bimatoprost with timolol in patients with glaucoma or ocular hypertension.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2004 |
Intraocular pressure-reducing effects and safety of latanoprost versus timolol in patients with chronic angle-closure glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Timolol | 2004 |
Efficacy and safety of the fixed combinations latanoprost/timolol versus dorzolamide/timolol in patients with elevated intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
A three-year prospective, randomized and open comparison between latanoprost and timolol in Japanese normal-tension glaucoma patients.
Topics: Adult; Aged; Analysis of Variance; Antihypertensive Agents; Drug Administration Schedule; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Visual Fields | 2004 |
Efficacy and safety of the latanoprost/timolol maleate fixed combination vs concomitant brimonidine and latanoprost therapy.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2004 |
Brimonidine 0.2% vs unoprostone 0.15% both added to timolol maleate 0.5% given twice daily to patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Dinoprost; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Timolol; Treatment Outcome | 2005 |
Dorzolamide/Timolol fixed combination versus concomitant administration of brimonidine and timolol in patients with elevated intraocular pressure: a 3-month comparison of efficacy, tolerability, and patient-reported measures.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Effects on aqueous flow of dorzolamide combined with either timolol or acetazolamide.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Antihypertensive Agents; Aqueous Humor; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Manometry; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 2004 |
Immediate postoperative use of a topical agent to prevent intraocular pressure elevation after pars plana vitrectomy with gas tamponade.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Female; Fluorocarbons; Humans; Intraocular Pressure; Male; Middle Aged; Postoperative Complications; Postoperative Period; Prospective Studies; Retinal Detachment; Retinal Perforations; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2004 |
A comparison of the fixed combination of latanoprost and timolol with the unfixed combination of brimonidine and timolol in patients with elevated intraocular pressure. A six month, evaluator masked, multicentre study in Europe.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Europe; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Timolol; Treatment Outcome | 2004 |
Ocular hypotensive effect and safety of brinzolamide ophthalmic solution in open angle glaucoma patients.
Topics: Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Consumer Product Safety; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Sulfonamides; Thiazines; Timolol | 2004 |
Daytime diurnal curve comparison between the fixed combinations of latanoprost 0.005%/timolol maleate 0.5% and dorzolamide 2%/timolol maleate 0.5%.
Topics: Adult; Aged; Antihypertensive Agents; Chronotherapy; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
Comparison of latanoprost with fixed-combination dorzolamide and timolol in adult patients with elevated intraocular pressure: an eight-week, randomized, open-label, parallel-group, multicenter study in Latin America.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2004 |
A 6-month randomized clinical trial of bimatoprost 0.03% versus the association of timolol 0.5% and latanoprost 0.005% in glaucomatous patients.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Safety; Single-Blind Method; Timolol; Treatment Outcome | 2004 |
Comparing the fixed combination dorzolamide-timolol (Cosopt) to concomitant administration of 2% dorzolamide (Trusopt) and 0.5% timolol -- a randomized controlled trial and a replacement study.
Topics: Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2004 |
Low incidence of iris pigmentation and eyelash changes in 2 randomized clinical trials with unoprostone isopropyl 0.15%.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Betaxolol; Dinoprost; Double-Blind Method; Eye Color; Eyelashes; Female; Glaucoma, Open-Angle; Hair Color; Humans; Hyperpigmentation; Incidence; Intraocular Pressure; Iris; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Photography; Timolol | 2004 |
[Comparison of the effects of latanoprost and timolol gel-forming solution on diurnal variation of intraocular pressure in normal-tension glaucoma].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2004 |
Comparison of the nocturnal effects of once-daily timolol and latanoprost on intraocular pressure.
Topics: Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sleep; Supine Position; Timolol; Tonometry, Ocular | 2004 |
Short term efficacy and safety in glaucoma patients changed to the latanoprost 0.005%/timolol maleate 0.5% fixed combination from monotherapies and adjunctive therapies.
Topics: Aged; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Failure; Treatment Outcome | 2004 |
Concomitant administration of travoprost and brinzolamide versus fixed latanoprost/timolol combined therapy: three-month comparison of efficacy and safety.
Topics: Cloprostenol; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Travoprost | 2004 |
[Short and long-term hypotensive effect of timolol-gel and latanoprost instillation in normal-tension glaucoma].
Topics: Adult; Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Time Factors; Timolol; Treatment Outcome | 2004 |
[Timolol 0.5%/dorzolamide 2% fixed combination versus timolol 0.5%/pilocarpine 2% fixed combination in primary open-angle glaucoma or ocular hypertensive patients].
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Preventive effect of lacrimal occlusion on topical timolol-induced bronchoconstriction in asthmatics.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Asthma; Blood Pressure; Bronchoconstriction; Female; Heart Rate; Humans; Intraocular Pressure; Lacrimal Duct Obstruction; Lung; Male; Middle Aged; Prospective Studies; Prostheses and Implants; Prosthesis Implantation; Respiratory Function Tests; Single-Blind Method; Timolol | 2004 |
Switching from latanoprost to fixed-combination latanoprost-timolol: a 21-day, randomized, double-masked, active-control study in patients with glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2004 |
A comparison of the effects of dorzolamide/timolol fixed combination versus latanoprost on intraocular pressure and pulsatile ocular blood flow in primary open-angle glaucoma patients.
Topics: Adult; Aged; Antihypertensive Agents; Blood Flow Velocity; Cross-Over Studies; Drug Therapy, Combination; Eye; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Pulsatile Flow; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography, Doppler | 2004 |
Configuration of the drainage angle, intraocular pressure, and optic disc cupping in subjects with chronic angle-closure glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Anterior Chamber; Antihypertensive Agents; Aqueous Humor; Chronic Disease; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Optic Disk; Optic Nerve Diseases; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Trabecular Meshwork | 2005 |
Bronchial reactivity in healthy individuals undergoing long-term topical treatment with beta-blockers.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Bronchial Hyperreactivity; Bronchoconstrictor Agents; Female; Forced Expiratory Volume; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Long-Term Care; Lung; Male; Methacholine Chloride; Middle Aged; Ophthalmic Solutions; Timolol; Trabeculectomy | 2005 |
Intraocular pressure and safety in glaucoma patients switching to latanoprost/timolol maleate fixed combination from mono- and adjunctive therapies.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Safety; Timolol; Tonometry, Ocular; Treatment Outcome | 2004 |
Interleukin-1beta tear concentration in glaucomatous and ocular hypertensive patients treated with preservative-free nonselective beta-blockers.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Conjunctival Diseases; Cross-Over Studies; Enzyme-Linked Immunosorbent Assay; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Interleukin-1; Intraocular Pressure; Keratitis; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Single-Blind Method; Tears; Timolol | 2005 |
Two-year follow-up of latanoprost 0.005% monotherapy after changing from previous glaucoma therapies.
Topics: Aged; Antihypertensive Agents; Drug Therapy, Combination; Female; Follow-Up Studies; Germany; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2004 |
The effects on the intraocular pressure and visual field resulting from a switch in the treatment from timolol to betaxolol.
Topics: Adult; Aged; Antihypertensive Agents; Betaxolol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Japan; Male; Ophthalmic Solutions; Time Factors; Timolol; Treatment Outcome; Visual Fields | 2004 |
Degree of angle closure and the intraocular pressure-lowering effect of latanoprost in subjects with chronic angle-closure glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Chronic Disease; Double-Blind Method; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Trabecular Meshwork | 2005 |
Comparison of the efficacy and safety of dorzolamide 2% when added to brimonidine 0.2% or timolol maleate 0.5% in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
The Low-pressure Glaucoma Treatment Study (LoGTS) study design and baseline characteristics of enrolled patients.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Disease Progression; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Research Design; Timolol; Visual Field Tests; Visual Fields | 2005 |
The influence of diclofenac ophthalmic solution on the intraocular pressure-lowering effect of topical 0.5% timolol and 0.005% latanoprost in primary open-angle glaucoma patients.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Diclofenac; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sample Size; Timolol; Tonometry, Ocular | 2005 |
Efficacy of the dorzolamide/timolol fixed combination versus latanoprost in the treatment of ocular hypertension or glaucoma: combined analysis of pooled data from two large randomized observer and patient-masked studies.
Topics: Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
The safety and efficacy of travoprost 0.004%/timolol 0.5% fixed combination ophthalmic solution.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost; Treatment Outcome | 2005 |
Timolol/dorzolamide combination therapy as initial treatment for intraocular pressure over 30 mm Hg.
Topics: Adult; Antihypertensive Agents; Circadian Rhythm; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2005 |
Twenty-four-hour control with latanoprost-timolol-fixed combination therapy vs latanoprost therapy.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Prospective Studies; Prostaglandins F, Synthetic; Safety; Timolol; Tonometry, Ocular; Visual Acuity | 2005 |
Efficacy and safety of a fixed combination of travoprost 0.004%/timolol 0.5% ophthalmic solution once daily for open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Travoprost; Treatment Outcome | 2005 |
Brimonidine and timolol fixed-combination therapy versus monotherapy: a 3-month randomized trial in patients with glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Double-Blind Method; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Timolol; Treatment Outcome | 2005 |
A three-month, multicenter, double-masked study of the safety and efficacy of travoprost 0.004%/timolol 0.5% ophthalmic solution compared to travoprost 0.004% ophthalmic solution and timolol 0.5% dosed concomitantly in subjects with open angle glaucoma or
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Travoprost; Treatment Outcome | 2005 |
A randomized trial assessing dorzolamide in patients with glaucoma who are younger than 6 years.
Topics: Antihypertensive Agents; Child, Preschool; Double-Blind Method; Female; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2005 |
Effect of dorzolamide and timolol on ocular blood flow in patients with primary open angle glaucoma and ocular hypertension.
Topics: Aged; Antihypertensive Agents; Choroid; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Regional Blood Flow; Regression Analysis; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2005 |
The efficacy and ocular discomfort of substituting brinzolamide for dorzolamide in combination therapy with latanoprost, timolol, and dorzolamide.
Topics: Aged; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Thiophenes; Timolol; Vision, Ocular | 2005 |
A 6-month assessment of bimatoprost 0.03% vs timolol maleate 0.5%: hypotensive efficacy, macular thickness and flare in ocular-hypertensive and glaucoma patients.
Topics: Adult; Amides; Anterior Chamber; Antihypertensive Agents; Bimatoprost; Cloprostenol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Macula Lutea; Ocular Hypertension; Prospective Studies; Timolol; Treatment Outcome | 2007 |
A 12-week, randomized, double-masked, multicenter study of the fixed combination of latanoprost and timolol in the evening versus the individual components.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2006 |
Comparison of the effects of brimonidine 0.2% and timolol 0.5% on retinal nerve fiber layer thickness in ocular hypertensive patients: a prospective, unmasked study.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Nerve Fibers; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Retina; Time Factors; Timolol | 2005 |
Comparison of latanoprost monotherapy and combined therapy of 0.5% timolol and 1% dorzolamide in chronic primary angle-closure glaucoma (CACG) in Japanese patients.
Topics: Aged; Antihypertensive Agents; Chronic Disease; Drug Combinations; Female; Glaucoma, Angle-Closure; Humans; Instillation, Drug; Intraocular Pressure; Japan; Latanoprost; Male; Ophthalmic Solutions; Patient Compliance; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2005 |
A comparison of the effects of 0.005% latanoprost and fixed combination dorzolamide/timolol on retrobulbar haemodynamics in previously untreated glaucoma patients.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
Efficacy and systemic side-effects of topical 0.5% timolol aqueous solution and 0.1% timolol hydrogel.
Topics: Absorption; Adrenergic beta-Antagonists; Adult; Area Under Curve; Biological Availability; Blood Pressure; Cross-Over Studies; Double-Blind Method; Exercise; Female; Heart Rate; Humans; Hydrogels; Intraocular Pressure; Male; Ophthalmic Solutions; Respiratory Function Tests; Timolol; Treatment Outcome | 2005 |
Efficacy of latanoprost or fixed-combination latanoprost-timolol in patients switched from a combination of timolol and a nonprostaglandin medication.
Topics: Adult; Aged; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retreatment; Timolol; Treatment Outcome | 2006 |
Comparison of a non-preserved 0.1% T-Gel eye gel (single dose unit) with a preserved 0.1% T-Gel eye gel (multidose) in ocular hypertension and glaucomatous patients.
Topics: Adrenergic beta-Antagonists; Aged; Analysis of Variance; Antihypertensive Agents; Drug Administration Schedule; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Timolol | 2006 |
Improved systemic safety and risk-benefit ratio of topical 0.1% timolol hydrogel compared with 0.5% timolol aqueous solution in the treatment of glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Biological Availability; Cross-Over Studies; Double-Blind Method; Exercise Test; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Risk Assessment; Spirometry; Tilt-Table Test; Timolol; Visual Acuity | 2006 |
A 6-week, double-masked, parallel-group study of the efficacy and safety of travoprost 0.004% compared with latanoprost 0:005%/timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2006 |
A randomized, investigator-masked, 4-week study comparing timolol maleate 0.5%, brinzolamide 1%, and brimonidine tartrate 0.2% as adjunctive therapies to travoprost 0.004% in adults with primary open-angle glaucoma or ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Cloprostenol; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Thiazines; Timolol; Travoprost | 2006 |
The effect of timolol-dorzolamide and timolol-pilocarpine combinations on ocular blood flow in patients with glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Ciliary Arteries; Cross-Over Studies; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Artery; Pilocarpine; Prospective Studies; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Ultrasonography, Doppler, Color | 2006 |
An evaluation of the rate of nonresponders to latanoprost therapy.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Resistance; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Timolol; Tonometry, Ocular | 2006 |
Effects of topical hypotensive drugs on circadian IOP, blood pressure, and calculated diastolic ocular perfusion pressure in patients with glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Circadian Rhythm; Diastole; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Perfusion; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2006 |
The effects of a timolol maleate gel-forming solution on normotensive beagle dogs.
Topics: Animals; Blood Pressure; Dogs; Female; Gels; Intraocular Pressure; Male; Ophthalmic Solutions; Pupil; Timolol | 2006 |
[Combined therapy in glaucoma treatment: travoprost 0.004% and brinzolamid].
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Sulfonamides; Thiazines; Timolol; Travoprost | 2006 |
Twice-daily 0.2% brimonidine-0.5% timolol fixed-combination therapy vs monotherapy with timolol or brimonidine in patients with glaucoma or ocular hypertension: a 12-month randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Timolol; Tonometry, Ocular; Treatment Outcome | 2006 |
Travoprost versus latanoprost combinations in glaucoma: economic evaluation based on visual field deficit progression.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Cloprostenol; Double-Blind Method; Drug Costs; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Timolol; Travoprost; Visual Fields | 2006 |
Comparison of the efficacy and safety of travoprost with a fixed-combination of dorzolamide and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Travoprost | 2006 |
A comparative analysis of the effects of the fixed combination of timolol and dorzolamide versus latanoprost plus timolol on ocular hemodynamics and visual function in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Visual Acuity | 2006 |
24-Hour control with a latanoprost-timolol fixed combination vs timolol alone.
Topics: Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome; Visual Acuity | 2006 |
[Effect of timolol on central corneal thickness and endothelial cell density].
Topics: Adult; Antihypertensive Agents; Cell Count; Cornea; Dose-Response Relationship, Drug; Double-Blind Method; Endothelial Cells; Female; Humans; Intraocular Pressure; Male; Middle Aged; Pilot Projects; Timolol | 2006 |
Visual field and intraocular pressure asymmetry in the low-pressure glaucoma treatment study.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aging; Brimonidine Tartrate; Circadian Rhythm; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Quinoxalines; Timolol; Visual Fields | 2007 |
Circadian intraocular pressure control with dorzolamide versus timolol maleate add-on treatments in primary open-angle glaucoma patients using latanoprost.
Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2007 |
Comparison of the ocular hypotensive effects of bimatoprost and timolol-dorzolamide combination in patients with elevated intraocular pressure: a 6-month study.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Single-Blind Method; Sulfonamides; Thiophenes; Timolol | 2007 |
Retrobulbar haemodynamic effects of the latanoprost/timolol and the dorzolamide/timolol fixed combinations in newly diagnosed glaucoma patients.
Topics: Aged; Aged, 80 and over; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Artery; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2007 |
Latanoprost versus timolol gel-forming solution once daily in primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2007 |
Influence of ocular hypotensive eyedrops on intraocular pressure fluctuation with postural change in eyes with normal-tension glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Posture; Prospective Studies; Prostaglandins F, Synthetic; Single-Blind Method; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Visual Field Tests | 2007 |
Comparing the fixed combination brimonidine-timolol versus fixed combination dorzolamide-timolol in patients with elevated intraocular pressure.
Topics: Aged; Brimonidine Tartrate; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Sulfonamides; Thiophenes; Timolol | 2007 |
A comparison of latanoprost monotherapy with a combination therapy of timolol/dorzolamide in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Drug Therapy, Combination; Eye Color; Eyelashes; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pain; Prostaglandins F, Synthetic; Pruritus; Sulfonamides; Thiophenes; Timolol | 2006 |
Comparison of the effects of bimatoprost and a fixed combination of latanoprost and timolol on circadian intraocular pressure.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome | 2007 |
Special considerations in low-tension glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Neuroprotective Agents; Optic Nerve Diseases; Quinoxalines; Retinal Ganglion Cells; Timolol; Vision Disorders; Visual Field Tests; Visual Fields | 2007 |
A comparison of the safety and intraocular pressure lowering of bimatoprost/timolol fixed combination versus latanoprost/timolol fixed combination in patients with open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Middle Aged; Prostaglandins F, Synthetic; Single-Blind Method; Timolol; Treatment Outcome | 2007 |
Intraocular pressure elevation within the first 24 hours after cataract surgery in patients with glaucoma or exfoliation syndrome.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Prospective Studies; Timolol; Tonometry, Ocular | 2008 |
Twenty-four-hour efficacy of the brimonidine/timolol fixed combination versus therapy with the unfixed components.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Cross-Over Studies; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Time Factors; Timolol; Treatment Outcome | 2008 |
Prophylactic use of timolol maleate to prevent intraocular pressure elevation after Nd-YAG laser posterior capsulotomy.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Child; Child, Preschool; Female; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Premedication; Prospective Studies; Timolol; Tonometry, Ocular; Visual Acuity | 2008 |
Intraocular pressure rise after primary posterior continuous curvilinear capsulorhexis with a fixed dorzolamide-timolol combination: randomized safety study with intraindividual comparison using an angulated and a nonangulated intraocular lens.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Capsulorhexis; Cataract; Combined Modality Therapy; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Prosthesis Design; Sulfonamides; Thiophenes; Timolol | 2007 |
Effect of antiglaucoma agents on postoperative intraocular pressure after cataract surgery with Viscoat.
Topics: Acetazolamide; Acetylcholine; Administration, Topical; Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Chondroitin; Chondroitin Sulfates; Double-Blind Method; Drug Combinations; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Lens Implantation, Intraocular; Male; Middle Aged; Ocular Hypertension; Phacoemulsification; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular | 2007 |
Circadian changes of intraocular pressure and ocular perfusion pressure after timolol or latanoprost in Caucasians with normal-tension glaucoma.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Timolol; White People | 2008 |
Predicting intraocular pressure change before initiating therapy: timolol versus latanoprost.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Cohort Studies; Comorbidity; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Linear Models; Male; Middle Aged; Predictive Value of Tests; Prevalence; Prostaglandins F, Synthetic; Timolol | 2008 |
Success rates for switching to dorzolamide/timolol fixed combination in timolol responders who are insufficiently controlled by latanoprost monotherapy.
Topics: Aged; Antihypertensive Agents; Cohort Studies; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Patient Satisfaction; Prospective Studies; Quality of Life; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Treatment Outcome | 2008 |
[Additive therapy with carboanhydrase inhibitors for open angle glaucoma previously treated with timolol 0.5% drops].
Topics: Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Sulfonamides; Thiazines; Thiophenes; Timolol | 2007 |
Comparison of the 24-hour intraocular pressure-lowering effects of latanoprost and dorzolamide/timolol fixed combination after 2 and 6 months of treatment.
Topics: Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Therapeutic Equivalency; Thiophenes; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2008 |
Comparison of the effects of dorzolamide-timolol fixed combination and brimonidine on intraocular pressure after phacoemulsification surgery.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Postoperative Care; Postoperative Complications; Prospective Studies; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2008 |
The effects of dorzolamide 2% and dorzolamide/timolol fixed combination on retinal and optic nerve head blood flow in primary open-angle glaucoma patients.
Topics: Aged; Analysis of Variance; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Optic Disk; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2008 |
Dorzolamide/timolol fixed combination versus latanoprost/timolol fixed combination in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
Latanoprost-induced stabilization of central visual function in patients with primary open-angle glaucoma.
Topics: Aged; Antihypertensive Agents; Blood Pressure; Contrast Sensitivity; Cross-Over Studies; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Polysaccharides, Bacterial; Prospective Studies; Prostaglandins F, Synthetic; Time Factors; Timolol; Visual Fields | 2008 |
Intraocular pressure reduction with travoprost/timolol fixed combination, with and without adjunctive brinzolamide, in glaucoma.
Topics: Aged; Cloprostenol; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Sulfonamides; Thiazines; Timolol; Travoprost | 2008 |
Effects of the timolol-dorzolamide fixed combination and latanoprost on circadian diastolic ocular perfusion pressure in glaucoma.
Topics: Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Diastole; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
Regulation of intraocular pressure and pupil size by beta-blockers and epinephrine.
Topics: Adrenergic beta-Antagonists; Adult; Atenolol; Double-Blind Method; Drug Interactions; Epinephrine; Female; Hemodynamics; Humans; Intraocular Pressure; Male; Propranolol; Pupil; Timolol | 1980 |
Timolol in uncontrolled childhood glaucomas.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Age Factors; Child; Child, Preschool; Clinical Trials as Topic; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular Pressure; Propanolamines; Timolol | 1981 |
Role of the beta-adrenergic receptor-binding agent 'timolol' in the treatment of open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Pilocarpine; Propanolamines; Timolol | 1982 |
Adrenergic beta-receptor blockers, adrenalin and intraocular pressure.
Topics: Administration, Oral; Administration, Topical; Adolescent; Adrenergic beta-Antagonists; Adult; Atenolol; Clinical Trials as Topic; Drug Combinations; Epinephrine; Female; Humans; Intraocular Pressure; Male; Middle Aged; Propranolol; Pupil; Random Allocation; Timolol | 1982 |
The comparative multiple-dose intraocular pressure responses of nadolol and timolol in glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Nadolol; Ocular Hypertension; Propanolamines; Timolol | 1982 |
[Comparative studies of initial pressure reduction using 0.3% metipranolol and 0.25% timolol in eyes with wide-angle glaucoma].
Topics: Adult; Aged; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Propanolamines; Time Factors; Timolol | 1983 |
[Metipranolol--a new beta-blocker].
Topics: Adrenergic beta-Antagonists; Aged; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Propanolamines; Timolol | 1983 |
Diacetyl nadolol: 3-month ocular hypotensive effect in glaucomatous eyes.
Topics: Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Nadolol; Ocular Hypertension; Propanolamines; Timolol | 1983 |
A combination of oral and topical beta-blockers with additive effects on intraocular pressure.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Propranolol; Random Allocation; Timolol | 1983 |
[Indications and contraindications of beta blockaders in the treatment of glaucoma].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Airway Resistance; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pindolol; Respiration; Timolol | 1984 |
Betaxolol and timolol.
Topics: Adrenergic beta-Antagonists; Betaxolol; Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1984 |
Blind randomised non-crossover long-term trial comparing topical timolol 0.25% with timolol 0.5% in the treatment of simple chronic glaucoma.
Topics: Administration, Topical; Aged; Chronic Disease; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Propanolamines; Random Allocation; Timolol | 1983 |
Effect of pindolol on intraocular pressure in glaucoma: pilot study and a randomised comparison with timolol.
Topics: Clinical Trials as Topic; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilot Projects; Pindolol; Random Allocation; Timolol | 1983 |
Effect of timolol eye drops in subjects receiving systemic propranolol therapy.
Topics: Adult; Aged; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Propranolol; Time Factors; Timolol | 1983 |
Betaxolol and timolol. A comparison of efficacy and side effects.
Topics: Aged; Betaxolol; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Prospective Studies; Pulse; Timolol | 1984 |
[Clinical suitability of pindolol eyedrops in the treatment of chronic open-angle glaucoma].
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pindolol; Timolol | 1984 |
The additional pressure-lowering effect in patients with glaucoma of pilocarpine 2 per cent, adrenaline 1 per cent, or guanethidine 3 per cent with adrenaline 0.5 per cent and timolol 0.25 per cent: a double-blind cross-over study.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Timolol | 1983 |
Timolol v guanethidine-epinephrine formulations in the treatment of glaucoma. An open clinical trial.
Topics: Adult; Aged; Aqueous Humor; Circadian Rhythm; Clinical Trials as Topic; Drug Combinations; Epinephrine; Female; Glaucoma; Guanethidine; Humans; Intraocular Pressure; Male; Middle Aged; Timolol | 1984 |
A clinical evaluation of the effects of topically applied levobunolol and timolol on increased intraocular pressure.
Topics: Administration, Topical; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Propanolamines; Time Factors; Timolol | 1982 |
Two blind randomized cross-over trials in the treatment of primary open angle glaucoma.
Topics: Aged; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Random Allocation; Timolol | 1981 |
Preoperative timolol and ocular compression in cataract surgery.
Topics: Acetazolamide; Aged; Anesthesia, Intravenous; Cataract Extraction; Female; Humans; Intraocular Pressure; Male; Mannitol; Middle Aged; Postoperative Complications; Premedication; Propanolamines; Timolol; Vitreous Body | 1982 |
Dose-related interaction between timolol and adrenaline.
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Drug Interactions; Epinephrine; Humans; Intraocular Pressure; Propanolamines; Random Allocation; Timolol | 1981 |
[Timolol in the treatment of uncontrolled glaucoma (author's transl)].
Topics: Adult; Clinical Trials as Topic; Female; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1980 |
Addition of timolol maleate to routine medical therapy: a clinical trial.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Pulse; Timolol | 1980 |
[Timoptic. Timolol maleate, MSD (author's transl)].
Topics: Adult; Aged; Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1980 |
Interaction of timolol and adrenaline.
Topics: Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1981 |
Long-term drift and continued efficacy after multiyear timolol therapy.
Topics: Acetazolamide; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Time Factors; Timolol | 1981 |
Timolol and epinephrine in primary open angle glaucoma. Transient additive effect.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1981 |
Timolol versus pilocarpine separately or combined with acetazolamide-effects on intraocular pressure.
Topics: Acetazolamide; Aged; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Propanolamines; Research Design; Timolol | 1980 |
[Comparative study between timolol and d-epinephrine in the treatment of open-angle glaucoma (author's transl)].
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Random Allocation; Timolol | 1981 |
Timolol. Canadian multicenter study.
Topics: Blood Pressure; Canada; Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Pulse; Timolol | 1981 |
Prophylactic timolol for the prevention of high intraocular pressure after cataract extraction. A randomized, prospective, double-blind trial.
Topics: Cataract Extraction; Clinical Trials as Topic; Double-Blind Method; Humans; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Random Allocation; Timolol | 1981 |
[Experiences in a double-blind study with different concentrations of timolol and pilocarpine (author's transl)].
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Pilocarpine; Propanolamines; Pulse; Timolol | 1980 |
A study of the intraocular pressure lowering effect of timolol and dipivalyl epinephrine.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1981 |
[Timolol eye drops in the treatment of glaucoma and ocular hypertension. A multicentre study].
Topics: Adult; Aged; Clinical Trials as Topic; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1981 |
Study of the additive effect of timolol and epinephrine in lowering intraocular pressure.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Random Allocation; Timolol | 1981 |
Timolol and metoprolol. A diurnal study of the ocular and systemic effects in glaucoma patients.
Topics: Aged; Blood Pressure; Circadian Rhythm; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Propanolamines; Timolol | 1981 |
Timolol and metoprolol in glaucoma. A comparison of the ocular hypotensive effect, local and systemic tolerance.
Topics: Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Propanolamines; Timolol | 1981 |
The effects of timolol maleate and acetazolamide on the rate of aqueous formation in normal human subjects.
Topics: Acetazolamide; Anterior Chamber; Aqueous Humor; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Humans; Intraocular Pressure; Propanolamines; Random Allocation; Timolol | 1982 |
Dose response of oral timolol combined with adrenaline.
Topics: Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine; Female; Humans; Intraocular Pressure; Middle Aged; Propanolamines; Random Allocation; Timolol | 1982 |
Timolol and epinephrine: long-term evaluation of concurrent administration.
Topics: Administration, Topical; Clinical Trials as Topic; Drug Interactions; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Timolol | 1982 |
A study of the intraocular pressure lowering effect of timolol and dipivalyl epinephrine.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1982 |
Additive effect of epinephrine to timolol therapy in primary open angle glaucoma.
Topics: Adult; Aged; Drug Administration Schedule; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1982 |
Timolol and acetazolamide. A study of concurrent administration.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1982 |
Short term effects of timolol in chronic glaucoma. A double blind study using computerized perimetry.
Topics: Aged; Chronic Disease; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol; Tonometry, Ocular; Visual Field Tests; Visual Fields | 1982 |
A diurnal study of the ocular hypotensive effect of metoprolol mounted on ophthalmic rods compared to timolol eye drops in glaucoma patients.
Topics: Aged; Blood Pressure; Circadian Rhythm; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1981 |
The effect of timolol and acetazolamide on transient intraocular pressure elevation following cataract extraction with alpha-chymotrypsin.
Topics: Acetazolamide; Administration, Oral; Cataract Extraction; Chymotrypsin; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Postoperative Complications; Propanolamines; Timolol | 1981 |
A noninvasive tonometer in the measurement of the effects of pindolol and timolol on intraocular pressure in normal subjects.
Topics: Adolescent; Adult; Female; Humans; Intraocular Pressure; Male; Pindolol; Propanolamines; Pulse; Timolol; Tonometry, Ocular | 1981 |
Initial and long-term effects of metoprolol and timolol on the intraocular pressure. A comparison in healthy subjects.
Topics: Adult; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Propanolamines; Random Allocation; Tears; Timolol | 1981 |
Dynamics and kinetics of ophthalmic timolol.
Topics: Blood Pressure; Double-Blind Method; Forced Expiratory Volume; Heart Rate; Humans; Intraocular Pressure; Kinetics; Male; Ophthalmic Solutions; Physical Exertion; Propanolamines; Pulse; Timolol | 1980 |
Acute effect of epinephrine on aqueous humor formation in the timolol-treated normal eye as measured by fluorophotometry.
Topics: Aqueous Humor; Double-Blind Method; Drug Synergism; Epinephrine; Fluoresceins; Humans; Intraocular Pressure; Photometry; Propanolamines; Random Allocation; Timolol | 1980 |
Timolol and epinephrine: a clinical study of ocular interactions.
Topics: Aged; Blood Pressure; Drug Interactions; Epinephrine; Evaluation Studies as Topic; Female; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Prospective Studies; Pulse; Pupil; Random Allocation; Timolol | 1980 |
Evaluation of timolol in chronic open-angle glaucoma. Once a day vs twice a day.
Topics: Adult; Aged; Drug Administration Schedule; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Pulse; Timolol | 1980 |
[Multicenter double-blind study with 0.25% timolol in Gelrite (TG) once daily vs. 0.25% timolol solution (TS) twice daily. German Study Group].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pharmaceutical Vehicles; Polysaccharides, Bacterial; Timolol | 1995 |
The effect of topical beta-adrenoceptor blocking agents on pulsatile ocular blood flow.
Topics: Adrenergic beta-Antagonists; Betaxolol; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Pulsatile Flow; Time Factors; Timolol | 1995 |
The Glaucoma Laser Trial (GLT): 6. Treatment group differences in visual field changes. Glaucoma Laser Trial Research Group.
Topics: Adult; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Male; Pilocarpine; Timolol; Trabeculectomy; Visual Acuity; Visual Fields | 1995 |
Retrobulbar arterial hemodynamic effects of betaxolol and timolol in normal-tension glaucoma.
Topics: Arteries; Betaxolol; Blood Flow Velocity; Cross-Over Studies; Double-Blind Method; Female; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Orbit; Prospective Studies; Timolol; Ultrasonography, Doppler, Color; Vascular Resistance | 1995 |
A double-masked, randomized 1-year study comparing dorzolamide (Trusopt), timolol, and betaxolol. International Dorzolamide Study Group.
Topics: Administration, Topical; Adolescent; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1995 |
Comparative phase III clinical trial of latanoprost and timolol in patients with elevated intraocular pressure.
Topics: Circadian Rhythm; Double-Blind Method; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol | 1995 |
Efficacy and safety of timolol/pilocarpine combination drops in glaucoma patients.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Timolol; Visual Acuity; Visual Fields | 1994 |
The cardiovascular, pulmonary, and ocular hypotensive effects of 0.2% brimonidine.
Topics: Adrenergic alpha-Agonists; Adult; Betaxolol; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Exercise Test; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Quinoxalines; Respiration; Timolol | 1995 |
Influence of topical anesthesia on tonometric values of intraocular pressure.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Anesthesia, Local; Anesthetics, Local; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Timolol; Tonometry, Ocular | 1994 |
Latanoprost administered once daily caused a maintained reduction of intraocular pressure in glaucoma patients treated concomitantly with timolol.
Topics: Aged; Aged, 80 and over; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Time Factors; Timolol | 1995 |
The efficacy of apraclonidine as an adjunct to timolol therapy. Apraclonidine Adjunctive Therapy Study Group.
Topics: Adrenergic alpha-Agonists; Chemotherapy, Adjuvant; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Synergism; Drug Tolerance; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1995 |
Long-term functional outcome after early surgery compared with laser and medicine in open-angle glaucoma.
Topics: Aged; Chronic Disease; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Longitudinal Studies; Middle Aged; Pilocarpine; Prospective Studies; Timolol; Trabeculectomy; Treatment Outcome; Visual Acuity; Visual Fields | 1994 |
Differences in the longterm effect of timolol and betaxolol on the pulsatile ocular blood flow.
Topics: Adult; Aged; Aged, 80 and over; Betaxolol; Blood Flow Velocity; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Pulsatile Flow; Timolol | 1994 |
Longterm effect of topical beta-blockers on intraocular pressure and visual field sensitivity in ocular hypertension and chronic open-angle glaucoma.
Topics: Administration, Topical; Adult; Aged; Betaxolol; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol; Tonometry, Ocular; Visual Field Tests; Visual Fields | 1994 |
Longterm visual field follow-up of glaucoma patients treated with beta-blockers.
Topics: Aged; Betaxolol; Blood Pressure; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol; Visual Field Tests; Visual Fields | 1994 |
Diurnal variation in pulsatile ocular blood flow in normal and glaucomatous eyes.
Topics: Aged; Blood Flow Velocity; Blood Pressure; Circadian Rhythm; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pulsatile Flow; Timolol; Tonometry, Ocular | 1994 |
[The additive effect of dipivefrin in patients with wide angle glaucoma treated with long-term beta-blocker therapy in comparison with clonidine].
Topics: Clonidine; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Timolol | 1994 |
Assessment of the ocular response to topical beta-adrenoceptor antagonists using accommodative microfluctuations.
Topics: Accommodation, Ocular; Administration, Topical; Adult; Betaxolol; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Time Factors; Timolol | 1994 |
Effect of timolol vs. acetazolamide on sodium hyaluronate-induced rise in intraocular pressure after cataract surgery.
Topics: Acetazolamide; Administration, Oral; Adult; Aged; Aged, 80 and over; Cataract Extraction; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postoperative Complications; Prospective Studies; Timolol | 1994 |
Nasolacrimal occlusion improves the therapeutic index of antiglaucoma medications.
Topics: Aged; Carbachol; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Nasolacrimal Duct; Ophthalmic Solutions; Pilocarpine; Timolol; Treatment Outcome | 1994 |
Aqueous flow in humans after adrenalectomy.
Topics: Adrenalectomy; Adult; Aqueous Humor; Circadian Rhythm; Epinephrine; Estrogen Replacement Therapy; Fluorophotometry; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Timolol | 1994 |
The contralateral reduction of intraocular pressure by timolol.
Topics: Administration, Topical; Adult; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Time Factors; Timolol | 1994 |
Double-masked comparative study of UF-021 and timolol ophthalmic solutions in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Blood Pressure; Dinoprost; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1993 |
Combined timolol and pilocarpine vs pilocarpine alone and timolol alone in the treatment of glaucoma.
Topics: Administration, Topical; Adult; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Timolol; Tonometry, Ocular | 1994 |
Effects of ocular carteolol and timolol on plasma high-density lipoprotein cholesterol level.
Topics: Administration, Topical; Adult; Carteolol; Cholesterol; Cholesterol, HDL; Double-Blind Method; Eye; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol | 1993 |
The effect of betaxolol and timolol on postoperative intraocular pressure.
Topics: Betaxolol; Cataract Extraction; Double-Blind Method; Humans; Intraocular Pressure; Lenses, Intraocular; Ocular Hypertension; Ophthalmic Solutions; Timolol; Tonometry, Ocular | 1993 |
Comparison of apraclonidine and timolol in chronic open-angle glaucoma. A three-month study.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Clonidine; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Timolol | 1993 |
A comparison of the ocular tolerability of a single dose of timolol and levobunolol in healthy normotensive volunteers.
Topics: Adult; Aged; Asthenopia; Double-Blind Method; Drug Tolerance; Eye; Female; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Timolol; Vision Disorders | 1993 |
Serial administration of adrenergic antagonist and agonist ("pulsatile therapy") reduces the incidence of long-term drift to timolol in humans.
Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Drug Administration Schedule; Drug Tolerance; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1996 |
Around-the-clock intraocular pressure reduction with once-daily application of latanoprost by itself or in combination with timolol.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Chronic Disease; Circadian Rhythm; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Posture; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 1996 |
Timolol hemihydrate vs timolol maleate to treat ocular hypertension and open-angle glaucoma.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Chronic Disease; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 1996 |
A six-month, randomized, double-masked study comparing latanoprost with timolol in open-angle glaucoma and ocular hypertension. The Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prostaglandins F, Synthetic; Timolol; Visual Acuity | 1996 |
Comparison of latanoprost and timolol in patients with ocular hypertension and glaucoma: a six-month masked, multicenter trial in the United States. The United States Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Conjunctiva; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Hyperemia; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prostaglandins F, Synthetic; Timolol; United States | 1996 |
A six-week dose-response study of the ocular hypotensive effect of dorzolamide with a one-year extension. Dorzolamide Dose-Response Study Group.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 1996 |
A comparison of latanoprost and timolol in primary open-angle glaucoma and ocular hypertension. A 12-week study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Conjunctiva; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 1996 |
A 90-day study of the efficacy and side effects of 0.25% and 0.5% apraclonidine vs 0.5% timolol. Apraclonidine Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Clonidine; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1996 |
A 6-month, randomized, double-masked comparison of latanoprost with timolol in patients with open angle glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Scandinavian and Nordic Countries; Timolol | 1996 |
The intraocular pressure lowering effect of timolol in gel-forming solution.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Drug Delivery Systems; Female; Finland; Follow-Up Studies; Gels; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Scandinavian and Nordic Countries; Timolol | 1996 |
A controlled clinical trial of dorzolamide: a single-centre subset of a multicentre study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
The use of dorzolamide and pilocarpine as adjunctive therapy to timolol in patients with elevated intraocular pressure. The Dorzolamide Additivity Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pilot Projects; Safety; Sulfonamides; Thiophenes; Timolol | 1996 |
Early postoperative intraocular pressure pattern in glaucomatous and nonglaucomatous patients.
Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Cataract Extraction; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lenses, Intraocular; Male; Ocular Hypertension; Postoperative Period; Random Allocation; Risk Factors; Timolol | 1996 |
Decrease of optic disc cupping and pallor of ocular hypertensives with timolol therapy.
Topics: Double-Blind Method; Female; Follow-Up Studies; Humans; Image Processing, Computer-Assisted; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Models, Biological; Multivariate Analysis; Ocular Hypertension; Optic Disk; Photography; Timolol; Treatment Outcome | 1995 |
A comparative evaluation of pilocarpine 1% and clonidine 0.125% versus timolol 0.5%.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Timolol | 1996 |
Latanoprost, a prostaglandin analog, for glaucoma therapy. Efficacy and safety after 1 year of treatment in 198 patients. Latanoprost Study Groups.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Exfoliation Syndrome; Eye Color; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Timolol; Visual Acuity; Visual Fields | 1996 |
A comparative study of the effects of timolol and latanoprost on blood flow velocity of the retrobulbar vessels.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Blood Flow Velocity; Ciliary Body; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Artery; Ophthalmic Solutions; Orbit; Prospective Studies; Prostaglandins F, Synthetic; Regional Blood Flow; Retinal Artery; Timolol; Ultrasonography, Doppler, Color | 1996 |
Clinical experience with brimonidine 0.2% and timolol 0.5% in glaucoma and ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol; Treatment Outcome | 1996 |
Effect of dapiprazole, an alpha-adrenergic blocking agent, on aqueous humor dynamics in pigmentary glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aqueous Humor; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Piperazines; Prospective Studies; Timolol; Tonometry, Ocular; Treatment Outcome; Triazoles | 1996 |
Efficacy of silicone punctal plugs as adjuncts to topical pharmacotherapy of glaucoma--a pilot study. Punctal Plugs in Glaucoma Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Combined Modality Therapy; Cross-Over Studies; Double-Blind Method; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Lacrimal Duct Obstruction; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Silicones; Timolol | 1996 |
Comparison of topical timolol gel to oral acetazolamide in the prophylaxis of viscoelastic-induced ocular hypertension after penetrating keratoplasty.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Gels; Humans; Hyaluronic Acid; Intraocular Pressure; Keratoplasty, Penetrating; Male; Ocular Hypertension; Postoperative Complications; Prospective Studies; Timolol | 1997 |
A comparison of Healon and Amvisc on the early postoperative pressure after extracapsular cataract extraction with implantation of posterior chamber lens.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Cataract Extraction; Female; Follow-Up Studies; Humans; Hyaluronic Acid; Intraocular Pressure; Lenses, Intraocular; Male; Ocular Hypertension; Ophthalmic Solutions; Postoperative Period; Prospective Studies; Regression Analysis; Timolol | 1996 |
A comparison of dorzolamide and timolol in patients with pseudoexfoliation and glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
The effect of latanoprost 0.005% once daily versus 0.0015% twice daily on intraocular pressure and aqueous humour protein concentration in glaucoma patients. A randomized, double-masked comparison with timolol 0.5%.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aqueous Humor; Blood-Aqueous Barrier; Cross-Over Studies; Double-Blind Method; Eye Proteins; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 1997 |
[Beta-blockers in the treatment of open-angle glaucoma].
Topics: Adrenergic beta-Antagonists; Betaxolol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Middle Aged; Timolol; Vital Capacity | 1996 |
Ocular hypotensive effect of topical ketanserin in timolol users.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Cross-Over Studies; Double-Blind Method; Female; Humans; Intraocular Pressure; Ketanserin; Male; Middle Aged; Retreatment; Serotonin Antagonists; Timolol | 1997 |
Effects on intraocular pressure and side effects of 0.005% latanoprost applied once daily, evening or morning. A comparison with timolol. Scandinavian Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 1995 |
Enhanced acute ocular hypotensive response to timolol with dexamethasone treatment.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Dexamethasone; Drug Synergism; Female; Glucocorticoids; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1997 |
Efficacy of a novel hydrogel formulation in human volunteers.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Circadian Rhythm; Cross-Over Studies; Drug Carriers; Female; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Polyethylene Glycols; Reference Values; Safety; Single-Blind Method; Timolol; Treatment Outcome | 1996 |
Clinical evaluation of UF-021 (Rescula; isopropyl unoprostone).
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Dinoprost; Drug Evaluation; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Timolol; Treatment Outcome | 1997 |
The incidence and time-course of latanoprost-induced iridial pigmentation as a function of eye color.
Topics: Adrenergic beta-Antagonists; Double-Blind Method; Europe; Eye Color; Glaucoma; Humans; Incidence; Intraocular Pressure; Iris; Iris Diseases; Latanoprost; Melanins; Melanosis; Ophthalmic Solutions; Prostaglandins F, Synthetic; Time Factors; Timolol; United States | 1997 |
Retinal capillary hemodynamics and VEP/pressure tolerance: evidence of retinal microcirculatory compromise in treated glaucomatous eyes.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Evoked Potentials, Visual; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Leukocytes; Male; Middle Aged; Muscarinic Agonists; Pilocarpine; Retinal Vessels; Timolol | 1997 |
A clinical trial of MK-507, Trusopt, for raised intraocular pressure--the Australian experience.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Australia; Betaxolol; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1996 |
Effect of timolol and UF-021 (a prostaglandin-related compound) on pulsatile ocular blood flow in normal volunteers.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Blood Pressure; Dinoprost; Double-Blind Method; Eye; Heart Rate; Humans; Intraocular Pressure; Ophthalmic Solutions; Pulsatile Flow; Reference Values; Reproducibility of Results; Timolol | 1997 |
A 1-year study of brimonidine twice daily in glaucoma and ocular hypertension. A controlled, randomized, multicenter clinical trial. Chronic Brimonidine Study Group.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pupil; Quinoxalines; Safety; Time Factors; Timolol; Treatment Outcome; Visual Acuity | 1997 |
Efficacy of carteolol hydrochloride 1% vs timolol maleate 0.5% in patients with increased intraocular pressure. Nocturnal Investigation of Glaucoma Hemodynamics Trial Study Group.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carteolol; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Treatment Outcome | 1997 |
Comparison of dorzolamide and timolol as suppressors of aqueous humor flow in humans.
Topics: Adrenergic beta-Antagonists; Adult; Aqueous Humor; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Synergism; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1997 |
Levobunolol 0.5% and timolol 0.5% to prevent intraocular pressure elevation after neodymium:YAG laser posterior capsulotomy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Cataract; Double-Blind Method; Female; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Levobunolol; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Premedication; Prospective Studies; Timolol | 1997 |
Timolol gel versus acetazolamide in the prophylaxis of ocular hypertension after phacoemulsification.
Topics: Acetazolamide; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Delayed-Action Preparations; Double-Blind Method; Female; Gels; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Premedication; Prospective Studies; Timolol | 1997 |
Short-term effect of apraclonidine on intraocular pressure in glaucoma patients receiving timolol and pilocarpine.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Clonidine; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Prospective Studies; Timolol | 1997 |
Latanoprost. Two years' experience of its use in the United Kingdom. Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prostaglandins F, Synthetic; Safety; Timolol; United Kingdom | 1998 |
The acute effect of topical beta-adrenoreceptor blocking agents on retinal and optic nerve head circulation.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Betaxolol; Blood Circulation; Blood Flow Velocity; Blood Pressure; Double-Blind Method; Female; Fluorescein Angiography; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Ophthalmic Solutions; Optic Disk; Retinal Vessels; Timolol | 1998 |
Ocular hypotensive effect of ketanserin in patients with primary open angle glaucoma.
Topics: Adrenergic beta-Antagonists; Blood Pressure; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Ketanserin; Male; Ophthalmic Solutions; Pupil; Serotonin Antagonists; Tears; Timolol; Treatment Outcome | 1997 |
Chronic topical eye preservative-free beta-blocker therapy effect on the ocular surface in glaucomatous patients.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Benzalkonium Compounds; Cornea; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Preservatives, Pharmaceutical; Single-Blind Method; Tears; Timolol | 1997 |
Prepared association of metipranolol 0.1% + pilocarpine 2% and of timolol 0.5% + pilocarpine 2%. Comparison of clinical efficacy and topical tolerability in the treatment of patients affected by POAG tonometrically uncontrolled with beta-blocker alone (tw
Topics: Administration, Topical; Adrenergic beta-Antagonists; Blood Pressure; Chronic Disease; Drug Therapy, Combination; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Metipranolol; Miotics; Ophthalmic Solutions; Pilocarpine; Timolol; Tonometry, Ocular; Treatment Outcome | 1997 |
Randomised, controlled trial of spirometric changes in elderly people receiving timolol or betaxolol as initial treatment for glaucoma.
Topics: Aged; Antihypertensive Agents; Betaxolol; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Respiration Disorders; Spirometry; Timolol | 1998 |
Comparison of the effect of latanoprost 0.005% and timolol 0.5% on the calculated ocular perfusion pressure in patients with normal-tension glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Cross-Over Studies; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 1998 |
Interaction between timolol eyedrops and oral nicardipine or oral diltiazem in healthy Japanese subjects.
Topics: Administration, Oral; Adrenergic beta-Antagonists; Adult; Asian People; Blood Pressure; Diltiazem; Double-Blind Method; Exercise Test; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Japan; Male; Nicardipine; Ophthalmic Solutions; Reference Values; Timolol; Vasodilator Agents | 1998 |
A multicenter study comparing dorzolamide and pilocarpine as adjunctive therapy to timolol: patient preference and impact on daily life.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Quality of Life; Sulfonamides; Thiophenes; Timolol; Visual Fields | 1998 |
A double-masked, randomized, 1-year study comparing the corneal effects of dorzolamide, timolol, and betaxolol. Dorzolamide Corneal Effects Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Carbonic Anhydrase Inhibitors; Cell Count; Double-Blind Method; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol | 1998 |
Comparison of two fixed combinations of latanoprost and timolol in open-angle glaucoma.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Treatment Outcome | 1998 |
Latanoprost treatment for glaucoma: effects of treating for 1 year and of switching from timolol. United States Latanoprost Study Group.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Double-Blind Method; Drug Administration Schedule; Eye Color; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Safety; Timolol | 1998 |
Clinical efficacy and safety of brinzolamide (Azopt), a new topical carbonic anhydrase inhibitor for primary open-angle glaucoma and ocular hypertension. Brinzolamide Primary Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 1998 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components. Dorzolamide-Timolol Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide. Dorzolamide-Timolol Combination Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
Twelve-month results of an ongoing randomized trial comparing brimonidine tartrate 0.2% and timolol 0.5% given twice daily in patients with glaucoma or ocular hypertension. Brimonidine Study Group 2.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol | 1998 |
Additive effect of dorzolamide on aqueous humor flow in patients receiving long-term treatment with timolol.
Topics: Adrenergic beta-Antagonists; Aged; Aqueous Humor; Carbonic Anhydrase Inhibitors; Cohort Studies; Drug Synergism; Female; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Direct costs of glaucoma management following initiation of medical therapy. A simulation model based on an observational study of glaucoma treatment in Germany.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cost-Benefit Analysis; Drug Costs; Drug Therapy, Combination; Female; Germany; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 1998 |
The effects of unoprostone isopropyl 0.12% and timolol maleate 0.5% on diurnal intraocular pressure.
Topics: Circadian Rhythm; Dinoprost; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Safety; Timolol; Visual Acuity | 1998 |
Two-year safety study of dorzolamide as monotherapy and with timolol and pilocarpine. Dorzolamide Safety Study Group.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Safety; Sulfonamides; Thiophenes; Timolol | 1998 |
Efficacy and safety of timolol solution once daily versus timolol gel in treating elevated intraocular pressure.
Topics: Blood Pressure; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Treatment Outcome; Visual Acuity | 1998 |
A comparison of the efficacy and tolerability of dorzolamide and acetazolamide as adjunctive therapy to timolol. Oral to Topical CAI Study Group.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Chemotherapy, Adjuvant; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Comparison of the safety and efficacy of the fixed combination of dorzolamide/timolol and the concomitant administration of dorzolamide and timolol: a clinical equivalence study. International Clinical Equivalence Study Group.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Brimonidine tartrate 0.2% twice daily vs timolol 0.5% twice daily: 1-year results in glaucoma patients. Brimonidine Study Group.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol; Treatment Outcome | 1999 |
Clinical use of a topical carbonic anhydrase inhibitor in patients affected by chronic simple glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Pilocarpine; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 1998 |
Latanoprost 0.005% in POAG: effects on IOP and ocular blood flow.
Topics: Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Choroid; Chronic Disease; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Single-Blind Method; Timolol; Treatment Outcome | 1998 |
The favorable effect of topical betaxolol and timolol on glaucomatous visual fields: a 2-year follow-up study.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Double-Blind Method; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Timolol; Visual Field Tests; Visual Fields | 1999 |
Comparison of short- and long-term effects of betaxolol and timolol on human retinal circulation.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Betaxolol; Blood Flow Velocity; Double-Blind Method; Drug Administration Schedule; Hemodynamics; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Retinal Vein; Time Factors; Timolol | 1998 |
A 12-month, randomized, double-masked study comparing latanoprost with timolol in pigmentary glaucoma.
Topics: Administration, Topical; Adult; Aqueous Humor; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Pigmentation Disorders; Prospective Studies; Prostaglandins F, Synthetic; Timolol | 1999 |
Intraocular pressure-lowering effects of latanoprost monotherapy versus latanoprost or pilocarpine in combination with timolol: a randomized, observer-masked multicenter study in patients with open-angle glaucoma. Italian Latanoprost Study Group.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Single-Blind Method; Timolol; Treatment Outcome | 1999 |
Pressure or progression?
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Brimonidine Tartrate; Disease Progression; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Timolol; Visual Fields | 1999 |
Patient preference, efficacy, and compliance with timolol maleate ophthalmic gel-forming solution versus timolol maleate ophthalmic solution in patients with ocular hypertension or open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Patient Compliance; Patient Satisfaction; Single-Blind Method; Timolol | 1999 |
Comparison of the early effects of brimonidine and apraclonidine as topical ocular hypotensive agents.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Fluorophotometry; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 1999 |
Immediate argon laser peripheral iridoplasty for acute attack of PACG (addendum to previous report)
Topics: Acute Disease; Aged; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Pilocarpine; Prospective Studies; Timolol; Visual Acuity | 1999 |
Diversity of response of optic nerve head circulation to timolol maleate in gel-forming solution.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Circulation; Blood Flow Velocity; Cross-Over Studies; Double-Blind Method; Eye Color; Female; Gels; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Optic Disk; Timolol | 1999 |
Modulation of Heidelberg Retinal Flowmeter parameter flow at the papilla of healthy subjects: effect of carbogen, oxygen, high intraocular pressure, and beta-blockers.
Topics: Administration, Inhalation; Adrenergic beta-Antagonists; Betaxolol; Blood Flow Velocity; Carbon Dioxide; Double-Blind Method; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Solutions; Optic Disk; Oxygen; Reference Values; Retinal Artery; Timolol | 1999 |
The short-term effect of adding brimonidine 0.2% to timolol treatment in patients with open-angle glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brimonidine Tartrate; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Timolol; Treatment Outcome | 1999 |
Comparison of 24-hour intraocular pressure reduction with two dosing regimens of latanoprost and timolol maleate in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Circadian Rhythm; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 1999 |
A comparison of the intraocular pressure-lowering effect of 0.5% timolol maleate and the docosanoid derivative of a PGF2 alpha metabolite, 0.12% unoprostone, in subjects with chronic open-angle glaucoma or ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Chronic Disease; Depression, Chemical; Dinoprost; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Statistics, Nonparametric; Time Factors; Timolol | 1999 |
The dorzolamide/timolol combination versus timolol plus pilocarpine: patient preference and impact on daily life. United States Patient Preference Study Group. International Patient Preference Study Group.
Topics: Activities of Daily Living; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Patient Satisfaction; Pilocarpine; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 1999 |
Comparison of 24 hour control with Timoptic 0.5% and Timoptic-XE 0.5% in exfoliation and primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Circadian Rhythm; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol | 1999 |
A randomized trial comparing the dorzolamide-timolol combination given twice daily to monotherapy with timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
The efficacy and safety of the dorzolamide-timolol combination versus the concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol; Visual Acuity; Visual Fields | 1999 |
A randomized trial in patients inadequately controlled with timolol alone comparing the dorzolamide-timolol combination to monotherapy with timolol or dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiophenes; Timolol | 1999 |
Central nervous system and plasma lipid profiles associated with carteolol and timolol in postmenopausal black women.
Topics: Adrenergic beta-Antagonists; Aged; Black People; Brain; Carteolol; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Postmenopause; Timolol; Visual Acuity | 1999 |
Primary open-angle glaucoma patients characterized by ocular vasospasm demonstrate a different ocular vascular response to timolol versus betaxolol.
Topics: Adrenergic beta-Antagonists; Betaxolol; Cross-Over Studies; Double-Blind Method; Eye; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Hypercapnia; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Spasm; Timolol; Ultrasonography, Doppler, Color; Vascular Resistance | 1999 |
Efficacy and safety of timolol solution once daily vs timolol gel added to latanoprost.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Safety; Timolol; Treatment Outcome | 1999 |
The comparative ocular hypotensive effect of apraclonidine with timolol maleate in exfoliation versus primary open-angle glaucoma patients.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Circadian Rhythm; Clonidine; Drug Therapy, Combination; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol | 1999 |
[Ocular pulse amplitude, intraocular pressure and beta blocker/carbonic anhydrase inhibition in combined therapy of primary open-angle glaucoma].
Topics: Adrenergic beta-Antagonists; Aged; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol | 1999 |
Comparison of the intraocular pressure lowering effect of latanoprost and a fixed combination of timolol-pilocarpine eye drops in patients insufficiently controlled with beta adrenergic antagonists. French Latanoprost Study Group, and the Swedish Latanopr
Topics: Adult; Aged; Antihypertensive Agents; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Timolol | 2000 |
Comparison of latanoprost monotherapy to dorzolamide combined with timolol in patients with glaucoma and ocular hypertension.A 3-month randomised study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
Drug interaction between cimetidine and timolol ophthalmic solution: effect on heart rate and intraocular pressure in healthy Japanese volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Cimetidine; Cytochrome P-450 CYP2D6 Inhibitors; Double-Blind Method; Drug Interactions; Enzyme Inhibitors; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Timolol | 2000 |
Adjunctive therapy with brinzolamide 1% ophthalmic suspension (Azopt) in patients with open-angle glaucoma or ocular hypertension maintained on timolol therapy.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Sulfonamides; Suspensions; Thiazines; Timolol; Treatment Outcome | 2000 |
The long-term safety and efficacy of brinzolamide 1.0% (azopt) in patients with primary open-angle glaucoma or ocular hypertension. The Brinzolamide Long-Term Therapy Study Group.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Evaluation; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Timolol | 2000 |
Effects of topical nipradilol, a beta blocking agent with alpha blocking and nitroglycerin-like activities, on intraocular pressure and aqueous dynamics in humans.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aqueous Humor; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Propanolamines; Timolol | 2000 |
Ongoing clinical assessment of the safety profile and efficacy of brimonidine compared with timolol: year-three results. Brimonidine Study Group II.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Quinoxalines; Timolol; Vision Tests | 2000 |
Comparison of the efficacy of betaxolol-brinzolamide and timolol-dorzolamide as suppressors of aqueous humor flow in human subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aqueous Humor; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
The lack of efficacy of topical beta-blockers, timolol and betaxolol on intraocular pressure in Nigerian healthy volunteers.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Betaxolol; Dose-Response Relationship, Drug; Female; Hemodynamics; Humans; Intraocular Pressure; Male; Single-Blind Method; Timolol | 1999 |
Comparison of the effects of 0.5% timolol maleate, 2% carteolol hydrochloride, and 0.3% metipranolol on intraocular pressure and perimetry findings and evaluation of their ocular and systemic effects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Carteolol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lipids; Male; Metipranolol; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol; Treatment Outcome; Visual Field Tests; Visual Fields | 2000 |
The use of topical aqueous suppressants in the prevention of postoperative intraocular pressure elevation after pars plana vitrectomy with long-acting gas tamponade.
Topics: Administration, Topical; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Clonidine; Fluorocarbons; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Quinoxalines; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Timolol; Vitrectomy | 2000 |
Latanoprost versus timolol gel to prevent ocular hypertension after phacoemulsification and intraocular lens implantation.
Topics: Adrenergic beta-Antagonists; Aged; Anterior Chamber; Antihypertensive Agents; Cell Count; Double-Blind Method; Female; Gels; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Ocular Hypertension; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2000 |
[The influence of 0.85% RS-timolol and 0.5% S-timolol on intraocular pressure and systemic arterial blood pressure, heart rate, ECG, expiratory capacity in patients with ocular hypertension and primary open-angle glaucoma].
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Electrocardiography; Expiratory Reserve Volume; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Severity of Illness Index; Timolol | 1999 |
Short-term effect of latanoprost and timolol eye drops on tear fluid and the ocular surface in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Conjunctiva; Cornea; Double-Blind Method; Female; Fluorescent Dyes; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rose Bengal; Tears; Timolol; Treatment Outcome | 2000 |
Latanoprost: experience of 2-year treatment in Scandinavia.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Exfoliation Syndrome; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Scandinavian and Nordic Countries; Timolol; Treatment Outcome | 2000 |
Additive effect of latanoprost to the combination of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Circadian Rhythm; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2000 |
Effects of systemic beta-blocker therapy on the efficacy and safety of topical brimonidine and timolol. Brimonidine Study Groups 1 and 2.
Topics: Administration, Oral; Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quinoxalines; Safety; Timolol | 2000 |
Comparison of the intraocular pressure-lowering effect of latanoprost and timolol in patients with chronic angle closure glaucoma: a preliminary study.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Chronic Disease; Double-Blind Method; Drug Evaluation; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2000 |
Effects of glaucoma medications on the cardiorespiratory and intraocular pressure status of newly diagnosed glaucoma patients.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Analysis of Variance; Betaxolol; Blood Pressure; Electrocardiography; Female; Forced Expiratory Volume; Glaucoma; Heart Failure; Humans; Intraocular Pressure; Lung Diseases, Obstructive; Male; Ophthalmic Solutions; Prostaglandins, Synthetic; Pulse; Timolol; Vital Capacity | 2000 |
Clinical success and quality of life with brimonidine 0.2% or timolol 0.5% used twice daily in glaucoma or ocular t hypertension: a randomized clinical trial. Brimonidine Outcomes Study Group I.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Blood Pressure; Brimonidine Tartrate; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Quality of Life; Quinoxalines; Safety; Surveys and Questionnaires; Timolol; Treatment Outcome | 2000 |
The additive intraocular pressure-lowering effect of latanoprost 0.005% daily once and pilocarpine 2% t.i.d. in patients with open-angle glaucoma or ocular hypertension. a 6-month, randomized, multicenter study. German Latanoprost Study Group.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Circadian Rhythm; Drug Administration Schedule; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2000 |
Effect of timolol, latanoprost, and dorzolamide on circadian IOP in glaucoma or ocular hypertension.
Topics: Aged; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2000 |
Long-term intraocular pressure-lowering efficacy and safety of timolol maleate gel-forming solution 0.5% compared with Timoptic XE 0.5% in a 12-month study.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Treatment Outcome | 2000 |
Effects of latanoprost and timolol-XE on hydrodynamics in the normal eye.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Female; Gels; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Pulsatile Flow; Sclera; Timolol; Tonometry, Ocular; Venous Pressure | 2000 |
Changes in ocular surface caused by antiglaucomatous eyedrops: prospective, randomised study for the comparison of 0.5% timolol v 0. 12% unoprostone.
Topics: Adrenergic beta-Antagonists; Aged; Dinoprost; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Optic Disk; Prospective Studies; Tears; Timolol; Visual Acuity | 2000 |
A comparison of dorzolamide-timolol combination versus the concomitant drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2000 |
Long-term effects of timolol therapy in ocular hypertension: a double-masked, randomised trial.
Topics: Adrenergic beta-Antagonists; Double-Blind Method; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Optic Disk; Prospective Studies; Risk Factors; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Fields | 2000 |
Comparison of the corneal effects of latanoprost, fixed combination latanoprost-timolol, and timolol: A double-masked, randomized, one-year study.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cell Count; Double-Blind Method; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol | 2001 |
Latanoprost versus combined therapy with timolol plus dorzolamide: IOP-lowering effect in open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
A comparative study on the effects of apraclonidine and timolol on the ophthalmic blood flow velocity waveforms.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Blood Pressure; Clonidine; Cross-Over Studies; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Ophthalmic Artery; Ophthalmic Solutions; Prospective Studies; Reference Values; Retinal Artery; Timolol; Ultrasonography, Doppler | 1999 |
Effect of timolol on anterior optic nerve blood flow in patients with primary open-angle glaucoma as assessed by the Heidelberg retina flowmeter.
Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ophthalmic Solutions; Optic Disk; Optic Nerve; Prospective Studies; Timolol; Tonometry, Ocular | 2001 |
Enhanced disruption of the blood-aqueous barrier and the incidence of angiographic cystoid macular edema by topical timolol and its preservative in early postoperative pseudophakia.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Anterior Eye Segment; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Benzalkonium Compounds; Blood-Aqueous Barrier; Capillary Permeability; Diclofenac; Double-Blind Method; Female; Fluorescein Angiography; Fluorometholone; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Macular Edema; Male; Ocular Hypertension; Preservatives, Pharmaceutical; Pseudophakia; Single-Blind Method; Timolol | 2001 |
The hypotensive efficacy of dorzolamide HCL-timolol maleate 0.50% vs concomitant use of the two drugs.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Sulfonamides; Therapeutic Equivalency; Thiophenes; Timolol | 2000 |
Comparison of the efficacy on intraocular pressure and retinal blood flow of a beta-blocker (timolol maleate) against the fixed association of a topical carbonic anhydrase (dorzolamide) and a beta-blocker (timolol maleate).
Topics: Administration, Topical; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Evaluation; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Solutions; Retinal Vessels; Sulfonamides; Thiophenes; Timolol | 2000 |
Hypotensive efficacy in primary open-angle glaucoma and ocular hypertension: latanoprost in monotherapy vs timolol and dorzolamide in association.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2000 |
The role of the uveoscleral outflow in the management of pigmentary glaucoma: a 24-month study comparing latanoprost with timolol.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Aqueous Humor; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; Sclera; Timolol; Uvea | 2000 |
The effect on diurnal intraocular pressure of the fixed combination of latanoprost 0.005% and timolol 0.5% in patients with ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2001 |
Aqueous humor flow in normal human eyes treated with brimonidine and timolol, alone and in combination.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aqueous Humor; Brimonidine Tartrate; Double-Blind Method; Drug Therapy, Combination; Female; Fluorescein; Fluorophotometry; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Quinoxalines; Timolol; Tonometry, Ocular | 2001 |
Effect on intraocular pressure during 24 hours after repeated administration of the fixed combination of latanoprost 0.005% and timolol 0.5% in patients with ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2001 |
Intraindividual comparison of the effects of a fixed dorzolamide-timolol combination and latanoprost on intraocular pressure after small incision cataract surgery.
Topics: Antihypertensive Agents; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Lens Implantation, Intraocular; Male; Middle Aged; Minimally Invasive Surgical Procedures; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2001 |
Comparison of once- or twice-daily bimatoprost with twice-daily timolol in patients with elevated IOP : a 3-month clinical trial.
Topics: Adult; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Treatment Outcome; Visual Acuity; Visual Fields | 2001 |
Brimonidine 0.2% given two or three times daily versus timolol maleate 0.5% in primary open-angle glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Brimonidine Tartrate; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Osmolar Concentration; Prospective Studies; Quinoxalines; Timolol | 2001 |
Additive IOP-reducing effect of latanoprost in patients insufficiently controlled on timolol.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2001 |
Six-month comparison of bimatoprost once-daily and twice-daily with timolol twice-daily in patients with elevated intraocular pressure.
Topics: Adrenergic beta-Antagonists; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Conjunctiva; Double-Blind Method; Eye Color; Female; Glaucoma; Humans; Hyperemia; Intraocular Pressure; Iris; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2001 |
Effect of timolol 0.5% gel and solution on pulmonary function in older glaucoma patients.
Topics: Adrenergic beta-Antagonists; Aged; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lung; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Tonometry, Ocular; Vital Capacity | 2001 |
Comparison of the ocular hypotensive lipid AGN 192024 with timolol: dosing, efficacy, and safety evaluation of a novel compound for glaucoma management.
Topics: Adult; Aged; Aged, 80 and over; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Hemodynamics; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2001 |
Influence of betaxolol and timolol on the venous tone in glaucoma patients.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Betaxolol; Blood Pressure; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Muscle, Smooth, Vascular; Ophthalmic Solutions; Timolol; Tonometry, Ocular; Valsalva Maneuver; Venous Pressure | 1999 |
A 7 year prospective comparative study of three topical beta blockers in the management of primary open angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Carteolol; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Linear Models; Male; Prospective Studies; Survival Analysis; Timolol; Trabeculectomy; Treatment Outcome; Visual Fields | 2001 |
Intraocular pressure over 24 hours after repeated administration of latanoprost 0.005% or timolol gel-forming solution 0.5% in patients with ocular hypertension.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Circadian Rhythm; Cross-Over Studies; Female; Gels; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol | 2001 |
Comparison of topical brinzolamide 1% and dorzolamide 2% eye drops given twice daily in addition to timolol 0.5% in patients with primary open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol; Treatment Outcome | 2001 |
Treatment of intraocular pressure elevation after photorefractive keratectomy.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Fluorometholone; Glucocorticoids; Humans; Intraocular Pressure; Lasers, Excimer; Male; Ocular Hypertension; Ophthalmic Solutions; Photorefractive Keratectomy; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2001 |
Comparison of the additive intraocular pressure-lowering effect of latanoprost and dorzolamide when added to timolol in patients with open-angle glaucoma or ocular hypertension: a randomized, open-label, multicenter study in Greece.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Travoprost compared with latanoprost and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pigmentation Disorders; Prodrugs; Prostaglandins F, Synthetic; Safety; Timolol; Travoprost; Treatment Outcome | 2001 |
Effect of dorzolamide timolol combination versus timolol 0.5% on ocular bloodflow in patients with primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Blood Flow Velocity; Ciliary Arteries; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Eye; Fluorescein Angiography; Glaucoma, Open-Angle; Humans; Indocyanine Green; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Artery; Ophthalmic Solutions; Ophthalmoscopy; Regional Blood Flow; Retinal Artery; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Ultrasonography; Visual Acuity | 2001 |
[Clinical evaluation of isopropyl unoprostone (Rescula), in the adjunctive treatment of primary open angle glaucoma].
Topics: Administration, Topical; Antihypertensive Agents; Dinoprost; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2001 |
Lack of long-term drift in timolol's effectiveness in patients with ocular hypertension.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Double-Blind Method; Drug Tolerance; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Prospective Studies; Timolol | 2001 |
[Prevention of early postoperative increase in intraocular pressure after phacoemulsification. Comparison of different antiglaucoma drugs].
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Middle Aged; Ophthalmic Solutions; Phacoemulsification; Polysaccharides, Bacterial; Postoperative Care; Postoperative Complications; Quinoxalines; Sulfonamides; Thiophenes; Time Factors; Timolol | 2001 |
Comparison of aqueous and gellan ophthalmic timolol with placebo on the 24-hour heart rate response in patients on treatment for glaucoma.
Topics: Adrenergic beta-Antagonists; Circadian Rhythm; Cross-Over Studies; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol | 2001 |
Comparison of topical travoprost eye drops given once daily and timolol 0.5% given twice daily in patients with open-angle glaucoma or ocular hypertension.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Cloprostenol; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost; Treatment Outcome | 2001 |
Evaluation of travoprost as adjunctive therapy in patients with uncontrolled intraocular pressure while using timolol 0.5%.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Antihypertensive Agents; Chemotherapy, Adjuvant; Cloprostenol; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Travoprost | 2001 |
A double-masked randomized comparison of the efficacy and safety of unoprostone with timolol and betaxolol in patients with primary open-angle glaucoma including pseudoexfoliation glaucoma or ocular hypertension. 6 month data.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Betaxolol; Dinoprost; Double-Blind Method; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pupil; Safety; Timolol; Visual Acuity; Visual Fields | 2002 |
Ocular surface changes induced by topical application of latanoprost and timolol: a short-term study in glaucomatous patients with and without allergic conjunctivitis.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Benzalkonium Compounds; Conjunctiva; Conjunctivitis, Allergic; Cross-Over Studies; Eosinophils; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Leukocyte Count; Lymphocytes; Male; Middle Aged; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Tears; Timolol | 2001 |
A short term study of the additive effect of timolol and brimonidine on intraocular pressure.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Blood Pressure; Brimonidine Tartrate; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Quinoxalines; Timolol | 2002 |
Bimatoprost vs. timolol.
Topics: Adrenergic beta-Antagonists; Amides; Antihypertensive Agents; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Glaucoma; Humans; Intraocular Pressure; Lipids; Ophthalmic Solutions; Timolol | 2002 |
Comparison of travoprost 0.0015% and 0.004% with timolol 0.5% in patients with elevated intraocular pressure: a 6-month, masked, multicenter trial.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cloprostenol; Double-Blind Method; Drug Evaluation; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Safety; Timolol; Travoprost; Treatment Outcome | 2002 |
A comparison of the efficacy and tolerability of 0.5% timolol maleate ophthalmic gel-forming solution QD and 0.5% levobunolol hydrochloride BID in patients with ocular hypertension or open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Cross-Over Studies; Double-Blind Method; Female; Gels; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Ocular Hypertension; Ophthalmic Solutions; Timolol | 2002 |
A comparison of once-daily morning vs evening dosing of concomitant latanoprost/timolol.
Topics: Antihypertensive Agents; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Greece; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Timolol | 2002 |
Timolol maleate 0.5% versus timolol maleate in gel forming solution 0.5% (Timolol GFS) in open angle glaucoma in India. Preliminary safety and efficacy study.
Topics: Adrenergic beta-Antagonists; Cross-Over Studies; Female; Gels; Glaucoma, Open-Angle; Humans; India; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Safety; Timolol | 2002 |
Latanoprost and timolol combination therapy vs monotherapy: one-year randomized trial.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Safety; Timolol; Treatment Outcome | 2002 |
Tolerability and efficacy of dorzolamide versus acetazolamide added to timolol.
Topics: Acetazolamide; Administration, Oral; Administration, Topical; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 2002 |
Systemic bioavailability and cardiopulmonary effects of 0.5% timolol eyedrops.
Topics: Absorption; Adrenergic beta-Antagonists; Adult; Area Under Curve; Biological Availability; Blood Pressure; Cross-Over Studies; Eye; Female; Forced Expiratory Volume; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Timolol; Vital Capacity | 2002 |
[A new beta-blocking agent in the treatment of chronic open-angle glaucoma: timolol maleate. Effect of instillation of 1 drop on the intraocular pressure].
Topics: Adolescent; Adult; Aged; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Propanolamines; Timolol | 1978 |
Timolol. A beta-adrenergic blocking agent for the treatment of glaucoma.
Topics: Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Placebos; Propanolamines; Reflex, Pupillary; Timolol; Visual Acuity | 1977 |
Timolol, dose response and duration of action.
Topics: Adult; Clinical Trials as Topic; Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Placebos; Propanolamines; Time Factors; Timolol | 1977 |
The effect of 1.5% timolol maleate on intraocular pressure.
Topics: Administration, Topical; Clinical Trials as Topic; Depression, Chemical; Double-Blind Method; Epinephrine; Humans; Intraocular Pressure; Placebos; Propanolamines; Technology, Pharmaceutical; Timolol | 1978 |
Long-term experience with timolol ophthalmic solution in patients with open-angle glaucoma.
Topics: Adult; Clinical Trials as Topic; Depression, Chemical; Evaluation Studies as Topic; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Pulse; Timolol | 1978 |
Clinical trial comparing timolol ophthalmic solution to pilocarpine in open-angle glaucoma.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Propanolamines; Pulse; Timolol | 1978 |
[Experiences with timolol in treatment of glaucoma (author's transl)].
Topics: Chemical Phenomena; Chemistry; Clinical Trials as Topic; Double-Blind Method; Drug Tolerance; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Timolol | 1978 |
A comparison of the effects of timolol and epinephrine on intraocular pressure.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1978 |
The mechanism of timolol in lowering intraocular pressure. In the normal eye.
Topics: Adult; Anterior Chamber; Aqueous Humor; Clinical Trials as Topic; Endothelium; Eye Color; Female; Fluorometry; Humans; Intraocular Pressure; Male; Permeability; Photometry; Placebos; Propanolamines; Timolol | 1978 |
[Drug tolerance of glaucomatous eyes to beta-receptor blockers].
Topics: Adult; Bupranolol; Clinical Trials as Topic; Drug Tolerance; Female; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1978 |
Timolol maleate: efficacy and safety.
Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1979 |
[Comparative study of atenolol and timolol in the treatment of ocular hypertension].
Topics: Atenolol; Clinical Trials as Topic; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1978 |
[Efficacy and safety of long-term maintenance treatment with timolol ophthalmic solution in chronic open-angle glaucoma (author's transl)].
Topics: Aphakia, Postcataract; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Propanolamines; Time Factors; Timolol | 1979 |
Interaction of topical and oral timolol in glaucoma.
Topics: Administration, Oral; Administration, Topical; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Propanolamines; Pulse; Timolol | 1979 |
[Timolol: long-term results, tolerance test and early-morning measurements (author's transl)].
Topics: Adult; Aged; Clinical Trials as Topic; Drug Evaluation; Drug Tolerance; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Optic Disk; Propanolamines; Timolol; Visual Fields | 1979 |
Timolol and epinephrine. Comparisin of efficacy and side effects.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Random Allocation; Timolol | 1979 |
Timolol plus maximum-tolerated antiglaucoma therapy.
Topics: Adult; Aged; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Parasympathomimetics; Placebos; Propanolamines; Sympathomimetics; Timolol | 1979 |
Timolol maleate--a new glaucoma medication?
Topics: Animals; Clinical Trials as Topic; Dogs; Glaucoma; Haplorhini; Humans; Intraocular Pressure; Propanolamines; Rabbits; Timolol | 1977 |
[Comparative study between timolol and pilocarpine in the treatment of open-angle glaucoma (author's transl)].
Topics: Double-Blind Method; Evaluation Studies as Topic; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Timolol | 1979 |
Effects of timolol and Daranide on elevated intraocular pressure after aphakic keratoplasty.
Topics: Adult; Aged; Aphakia, Postcataract; Carbonic Anhydrase Inhibitors; Cornea; Dichlorphenamide; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Postoperative Complications; Propanolamines; Random Allocation; Timolol | 1979 |
Timolol. A new drug for management of chronic simple glaucoma.
Topics: Adult; Aged; Albuterol; Animals; Epinephrine; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Middle Aged; Norepinephrine; Pilocarpine; Propanolamines; Rabbits; Timolol | 1978 |
Timolol-pilocarpine fixed-ratio combinations in the treatment of chronic open angle glaucoma. A controlled multicenter study of 48 weeks. Scandinavian Timpilo Study Group.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Osmolar Concentration; Pilocarpine; Timolol; Visual Acuity | 1992 |
Effects of timolol and acetazolamide on intraocular pressure elevation following argon laser iridotomy.
Topics: Acetazolamide; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Middle Aged; Postoperative Complications; Preoperative Care; Timolol | 1992 |
Assessment of bronchial effects following topical administration of butylamino-phenoxy-propanol-acetate, an oculoselective beta-adrenoceptor blocker in asthmatic subjects.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Asthma; Blood Pressure; Bronchoconstriction; Forced Expiratory Volume; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Protease Inhibitors; Respiratory Mechanics; Timolol | 1992 |
Effects of the association of alpha and beta-blocking agents in glaucoma.
Topics: Adrenergic alpha-Antagonists; Aged; Contrast Sensitivity; Double-Blind Method; Drug Combinations; Flicker Fusion; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Piperazines; Placebos; Timolol; Triazoles; Visual Fields | 1992 |
Ocular hypotensive effects of medifoxamine.
Topics: Administration, Oral; Adult; Antidepressive Agents; Double-Blind Method; Ethylamines; Female; Humans; Intraocular Pressure; Male; Random Allocation; Timolol | 1992 |
[Betoptic, a new possibility in the treatment of glaucoma].
Topics: Aged; Aged, 80 and over; Betaxolol; Blood Pressure; Glaucoma; Humans; Intraocular Pressure; Timolol | 1992 |
Six week safety study of 2% MK-927 administered twice daily to ocular hypertensive volunteers.
Topics: Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Double-Blind Method; Drug Administration Schedule; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Safety; Sulfonamides; Thiophenes; Timolol | 1992 |
Acetazolamide but not timolol lowers aqueous humor flow in sleeping humans.
Topics: Acetazolamide; Aqueous Humor; Double-Blind Method; Humans; Intraocular Pressure; Ophthalmic Solutions; Placebos; Secretory Rate; Sleep; Timolol | 1992 |
Effect of timolol versus pilocarpine on visual field progression in patients with primary open-angle glaucoma.
Topics: Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Pilocarpine; Prospective Studies; Timolol; Visual Acuity; Visual Fields | 1992 |
The effect of Healon and timolol on early postoperative intraocular pressure after extracapsular cataract extraction with implantation of a posterior chamber lens.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Cataract Extraction; Double-Blind Method; Female; Humans; Hyaluronic Acid; Intraocular Pressure; Lenses, Intraocular; Male; Middle Aged; Ocular Hypertension; Postoperative Complications; Prospective Studies; Timolol; Tonometry, Ocular | 1992 |
Long-term effect of ophthalmic beta-adrenoceptor antagonists on intraocular pressure and retinal sensitivity in primary open-angle glaucoma.
Topics: Aged; Betaxolol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Random Allocation; Retina; Sensory Thresholds; Timolol; Tonometry, Ocular; Visual Fields | 1992 |
Therapeutic index of pilocarpine, carbachol, and timolol with nasolacrimal occlusion.
Topics: Absorption; Carbachol; Chronic Disease; Cornea; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lacrimal Duct Obstruction; Nasolacrimal Duct; Pilocarpine; Placebos; Timolol | 1992 |
Myopia progression in young school children. A prospective study of myopia progression and the effect of a trial with bifocal lenses and beta blocker eye drops.
Topics: Child; Eyeglasses; Female; Humans; Intraocular Pressure; Male; Myopia; Ophthalmic Solutions; Prospective Studies; Timolol | 1991 |
[Intraocular pressure changes after Nd:YAG laser capsulotomy with preoperative use of timolol].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cataract Extraction; Child; Female; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Male; Middle Aged; Ocular Hypertension; Postoperative Period; Premedication; Timolol | 1991 |
Effects of topical flurbiprofen on the intraocular pressure lowering effects of apraclonidine and timolol.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adult; Clonidine; Double-Blind Method; Evaluation Studies as Topic; Female; Flurbiprofen; Humans; Intraocular Pressure; Male; Middle Aged; Premedication; Prospective Studies; Timolol | 1991 |
Apraclonidine and timolol. Combined effects in previously untreated normal subjects.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Aqueous Humor; Circadian Rhythm; Clonidine; Drug Therapy, Combination; Fluorescein; Fluoresceins; Humans; Intraocular Pressure; Random Allocation; Timolol | 1991 |
Additive effect of 1% apraclonidine hydrochloride to nonselective beta-blockers.
Topics: Adrenergic alpha-Agonists; Clonidine; Double-Blind Method; Drug Synergism; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Ocular Hypertension; Prospective Studies; Random Allocation; Timolol | 1991 |
Effect of apraclonidine in long-term timolol users.
Topics: Adrenergic alpha-Agonists; Aged; Aqueous Humor; Clonidine; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Secretory Rate; Timolol | 1991 |
[Additive effect of timolol and the local carbonic anhydrase inhibitor MK-417 (sezolamide)].
Topics: Aged; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Sulfonamides; Thiophenes; Timolol | 1991 |
A 3-month comparison of 1% and 2% carteolol and 0.5% timolol in open-angle glaucoma.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Blood Pressure; Carteolol; Dosage Forms; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Timolol | 1991 |
Occurrence of disc haemorrhages in open-angle glaucoma treated with pilocarpine or timolol.
Topics: Aged; Aged, 80 and over; Female; Glaucoma, Open-Angle; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Optic Disk; Pilocarpine; Premedication; Retinal Hemorrhage; Timolol | 1991 |
[Influence of topical administration of diclofenac on the reduction of intraocular pressure induced by timolol in healthy subjects].
Topics: Administration, Topical; Depression, Chemical; Diclofenac; Double-Blind Method; Drug Evaluation; Drug Interactions; Humans; Intraocular Pressure; Time Factors; Timolol | 1991 |
Evaluation of once-daily levobunolol 0.25% and timolol 0.25% therapy for increased intraocular pressure.
Topics: Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Administration Schedule; Evaluation Studies as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1991 |
[Effect of betaxolol and timolol on visual fields in glaucoma patients].
Topics: Betaxolol; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Prospective Studies; Timolol; Visual Fields | 1991 |
The Glaucoma Laser Trial: 4. Contralateral effects of timolol on the intraocular pressure of eyes treated with ALT. GLT Research Group.
Topics: Adult; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Timolol; Tonometry, Ocular; Trabeculectomy | 1991 |
Effect of timolol on human retinal, choroidal and optic nerve head circulation.
Topics: Administration, Topical; Adult; Blood Flow Velocity; Choroid; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Optic Disk; Regional Blood Flow; Retinal Artery; Timolol | 1991 |
Influence of betaxolol and timolol on the visual fields of patients with glaucoma.
Topics: Aged; Betaxolol; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Timolol; Visual Field Tests; Visual Fields | 1991 |
Apraclonidine hydrochloride: an evaluation of plasma concentrations, and a comparison of its intraocular pressure lowering and cardiovascular effects to timolol maleate.
Topics: Adrenergic alpha-Agonists; Adult; Blood Pressure; Clonidine; Double-Blind Method; Evaluation Studies as Topic; Female; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol | 1990 |
Follicular conjunctivitis associated with apraclonidine.
Topics: Adult; Clonidine; Conjunctivitis; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Timolol | 1991 |
Effect of two weeks of timolol maleate treatment on the normal retinal circulation.
Topics: Administration, Topical; Adult; Blood Pressure; Double-Blind Method; Fundus Oculi; Heart Rate; Humans; Intraocular Pressure; Photography; Random Allocation; Regional Blood Flow; Retinal Vessels; Timolol; Ultrasonics | 1991 |
Adrenergic and adrenolytic effects on intraocular pressure.
Topics: Administration, Topical; Analysis of Variance; Drug Therapy, Combination; Epinephrine; Humans; Intraocular Pressure; Ocular Hypertension; Pindolol; Placebos; Timolol | 1991 |
A comparison of treated and untreated glaucoma suspects.
Topics: Aged; Female; Follow-Up Studies; Glaucoma; Humans; Incidence; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Optic Disk; Prospective Studies; Retinal Hemorrhage; Survival Analysis; Timolol; Visual Fields | 1991 |
The effect of topical antiglaucoma drugs on the results of high-pass resolution perimetry.
Topics: Administration, Topical; Aged; Betaxolol; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Pupil; Timolol; Visual Field Tests; Visual Fields | 1991 |
Effect of a topical beta-adrenergic receptor antagonist on the dynamics of steady-state accommodation.
Topics: Accommodation, Ocular; Adult; Choroid; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Optometry; Pulse; Timolol | 1991 |
[Clinical trial of Timoptic used for inhibiting the development of keratoconus].
Topics: Adolescent; Adult; Female; Humans; Intraocular Pressure; Keratoconus; Male; Middle Aged; Ophthalmic Solutions; Timolol | 1990 |
Effect of timolol maleate on the retinal circulation of human eyes with ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Blood Flow Velocity; Blood Pressure; Double-Blind Method; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Photography; Random Allocation; Retinal Vein; Rheology; Timolol | 1990 |
[Primary open-angle glaucoma. Effects of an eyedrop combining timolol and pilocarpine on the ocular pressure].
Topics: Aged; Double-Blind Method; Drug Combinations; Drug Evaluation; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Pilocarpine; Timolol | 1990 |
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Pilocarpine; Prognosis; Timolol; Trabeculectomy | 1990 |
Steady-state pattern electroretinogram following long term unilateral administration of timolol to ocular hypertensive subjects.
Topics: Aged; Electroretinography; Female; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Pattern Recognition, Visual; Prospective Studies; Timolol | 1990 |
Effects of D-timolol and L-timolol eye drops on intraocular pressure and aqueous flow. A dose-response study in normal eyes.
Topics: Administration, Topical; Adult; Aqueous Humor; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Random Allocation; Stereoisomerism; Timolol; Tonometry, Ocular | 1990 |
The effect of adding prostaglandin F2 alpha-isopropylester to timolol in patients with open angle glaucoma.
Topics: Dinoprost; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Timolol | 1990 |
.008% timolol ophthalmic solution. A minimal-effect dose in a normal volunteer model.
Topics: Adult; Circadian Rhythm; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Timolol | 1990 |
Restoring sensitivity to timolol after long-term drift in primary open-angle glaucoma.
Topics: Aged; Drug Administration Schedule; Drug Tolerance; Epinephrine; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Pilot Projects; Randomized Controlled Trials as Topic; Timolol | 1990 |
Effect of ophthalmic administration of S-596 (Arotinolol) on intraocular pressure and haemodynamics in health volunteers: comparison with timolol.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Heart Rate; Hemodynamics; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Physical Exertion; Propanolamines; Pupil; Timolol | 1985 |
Topical timolol and the human retinal circulation.
Topics: Fundus Oculi; Humans; Intraocular Pressure; Ocular Hypertension; Random Allocation; Regional Blood Flow; Retina; Rheology; Timolol | 1989 |
Timolol treatment prevents or delays glaucomatous visual field loss in individuals with ocular hypertension: a five-year, randomized, double-masked, clinical trial.
Topics: Adult; Aged; Demography; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Longitudinal Studies; Male; Middle Aged; Ocular Hypertension; Optic Disk; Timolol; Visual Fields | 1989 |
Cardiovascular responses to metipranolol and timolol eyedrops in healthy volunteers.
Topics: Adult; Dose-Response Relationship, Drug; Female; Heart Rate; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Ophthalmic Solutions; Physical Exertion; Propanolamines; Timolol | 1989 |
Early visual field changes with beta-blocking agents.
Topics: Adrenergic beta-Antagonists; Betaxolol; Carteolol; Drug Evaluation, Preclinical; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Propanolamines; Timolol; Visual Fields | 1989 |
Is it worthwhile to add dipivefrin HCl 0.1% to topical beta 1-, beta 2-blocker therapy?
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Random Allocation; Timolol; Tonometry, Ocular | 1989 |
Changing therapy from timolol to betaxolol. Effect on intraocular pressure in selected patients with glaucoma. Timolol-Betaxolol Study Group.
Topics: Adrenergic beta-Antagonists; Betaxolol; Blood Pressure; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Pulse; Timolol; Vision, Ocular | 1989 |
Efficacy and safety of the combination therapy Pilogel/beta-blocker: interim results.
Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Circadian Rhythm; Clinical Trials as Topic; Drug Therapy, Combination; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Pilocarpine; Pupil; Refraction, Ocular; Timolol | 1989 |
Effects of D-timolol on intraocular pressure (IOP), beta blocking activity, and the dynamic changes of drug concentrations in aqueous humor.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Animals; Aqueous Humor; Female; Glaucoma; Humans; Hypotension; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Rabbits; Timolol | 1989 |
A comparison of the ocular hypotensive effect of 0.025% bromocriptine and 0.25% timolol eye drops in normal human volunteers.
Topics: Adult; Bromocriptine; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pupil; Timolol | 1989 |
Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate.
Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Epinephrine; Eye Diseases; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Timolol | 1989 |
Timolol-pilocarpine combined vs timolol and pilocarpine given separately.
Topics: Blood Pressure; Clinical Trials as Topic; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Multicenter Studies as Topic; Ophthalmic Solutions; Pilocarpine; Pulse; Random Allocation; Sweden; Time Factors; Timolol | 1989 |
Efficacy and safety of once-daily levobunolol for glaucoma therapy.
Topics: Administration, Topical; Adult; Aged; Blood Pressure; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Time Factors; Timolol; Tonometry, Ocular | 1989 |
[Treatment of glaucoma chronicum simplex with a combination of 0.5 percent timolol with 0.5 percent adrenaline plus 0.3 percent guanethidine].
Topics: Clinical Trials as Topic; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solutions; Retrospective Studies; Timolol | 1989 |
[The effect of levobunolol eyedrops on trabecular outflow of aqueous humor in chronic simple glaucoma].
Topics: Adult; Aqueous Humor; Clinical Trials as Topic; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Prospective Studies; Random Allocation; Stereoisomerism; Timolol; Trabecular Meshwork | 1989 |
The effect of betablockers with and without ISA on tonographic outflow facility.
Topics: Aqueous Humor; Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Pindolol; Random Allocation; Timolol; Tonometry, Ocular | 1989 |
Levobunolol. A four-year study of efficacy and safety in glaucoma treatment. The Levobunolol Study Group.
Topics: Adolescent; Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Longitudinal Studies; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Random Allocation; Time Factors; Timolol; Visual Fields | 1989 |
Laser trabeculoplasty versus medication treatment as primary therapy for glaucoma.
Topics: Acetazolamide; Clinical Trials as Topic; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Pilocarpine; Prospective Studies; Random Allocation; Timolol; Trabeculectomy; Visual Fields | 1989 |
[Effect of beta blockers on retinal hemodynamics. A double-blind study in healthy probands].
Topics: Adult; Blood Flow Velocity; Clinical Trials as Topic; Double-Blind Method; Female; Fluorescein Angiography; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Timolol | 1989 |
Long-term evaluation of timolol.
Topics: Adult; Aged; Clinical Trials as Topic; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol | 1989 |
"Outlier" intraocular pressure readings: valid or invalid for statistical analysis?
Topics: Analysis of Variance; Clinical Trials as Topic; Clonidine; Data Interpretation, Statistical; Double-Blind Method; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Random Allocation; Timolol | 1989 |
The benefit of early trabeculectomy versus conventional management in primary open angle glaucoma relative to severity of disease.
Topics: Chi-Square Distribution; Epinephrine; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Multicenter Studies as Topic; Prognosis; Prospective Studies; Random Allocation; Timolol; Trabeculectomy; Visual Acuity; Visual Fields | 1989 |
[Effect of carteolol and timolol eyedrops on the pressure tolerance of the optic nerve head].
Topics: Adaptation, Physiological; Adult; Carteolol; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Optic Disk; Propanolamines; Random Allocation; Timolol; Vision, Ocular | 1989 |
The time-course of intraocular pressure in timolol-treated and untreated glaucoma suspects.
Topics: Drug Evaluation; Follow-Up Studies; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Random Allocation; Time Factors; Timolol | 1989 |
Effect of topical timolol maleate on the ophthalmic artery blood pressure.
Topics: Administration, Topical; Adult; Blood Pressure; Brachial Artery; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Artery; Ophthalmodynamometry; Timolol | 1989 |
Reversibility by timolol of optic nerve disc cupping and pallor in ocular hypertensives.
Topics: Bradycardia; Heart Rate; Humans; Intraocular Pressure; Ocular Hypertension; Optic Disk; Time Factors; Timolol; Visual Fields | 1989 |
Quantification and monitoring of visual field defects and a prospective, randomized comparison of pilocarpine and timolol using computerized perimetry.
Topics: Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Prospective Studies; Random Allocation; Time Factors; Timolol; Visual Field Tests; Visual Fields | 1989 |
Overview of efficacy and local tolerability of a new timolol/pilocarpine combination.
Topics: Administration, Topical; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Timolol | 1989 |
The effect of a single oral dose of pergolide on intraocular pressure and pupil diameter.
Topics: Administration, Oral; Adult; Blood Pressure; Female; Humans; Intraocular Pressure; Male; Pergolide; Pulse; Pupil; Timolol | 1989 |
Timolol maleate in the control of myopia. A preliminary report.
Topics: Child; Clinical Trials as Topic; Female; Humans; Intraocular Pressure; Male; Myopia; Ophthalmic Solutions; Random Allocation; Timolol | 1988 |
Comparative efficacy of orally and topically administered beta blockers for chronic simple glaucoma.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Chronic Disease; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Nadolol; Propanolamines; Time Factors; Timolol | 1985 |
Timolol and aceclidine. A clinical study of interaction in the eye.
Topics: Aged; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Quinuclidines; Timolol | 1985 |
Levobunolol. A beta-adrenoceptor antagonist effective in the long-term treatment of glaucoma. The Levobunolol Study Group (Appended).
Topics: Adrenergic beta-Antagonists; Adult; Aged; Blood Pressure; Drug Evaluation; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Optic Disk; Time Factors; Timolol; Visual Fields | 1985 |
A blind randomised cross-over trial comparing metipranolol 0.3% with timolol 0.25% in open-angle glaucoma: a pilot study.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Metipranolol; Middle Aged; Propanolamines; Timolol | 1986 |
[Immediate effect of a topical beta-blocker on breakup time].
Topics: Adrenergic beta-Antagonists; Adult; Female; Humans; Intraocular Pressure; Levobunolol; Male; Metipranolol; Pindolol; Tears; Timolol | 1986 |
Additive effect of betaxolol and epinephrine in primary open angle glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Clinical Trials as Topic; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Random Allocation; Timolol | 1986 |
A single dose of three different ophthalmic beta-blockers antagonizes the chronotropic effect of isoproterenol in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Blood Pressure; Carteolol; Double-Blind Method; Heart Rate; Humans; Intraocular Pressure; Isoproterenol; Male; Metipranolol; Ophthalmic Solutions; Random Allocation; Timolol | 1987 |
[Mid-term results of a double-blind study comparing metipranolol to timolol in the treatment of primary open-angle glaucoma].
Topics: Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Metipranolol; Ophthalmic Solutions; Propanolamines; Time Factors; Timolol | 1987 |
Comparative efficacy of the beta-blockers for the prevention of increased intraocular pressure after cataract extraction.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Betaxolol; Cataract Extraction; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Postoperative Period; Propanolamines; Time Factors; Timolol | 1988 |
Beta-adrenergic receptor antagonism in myopia.
Topics: Accommodation, Ocular; Adrenergic beta-Antagonists; Adult; Convergence, Ocular; Cornea; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Myopia; Reading; Time Factors; Timolol | 1987 |
Celiprolol versus timolol and placebo: a two week double-blind comparison.
Topics: Adrenergic beta-Antagonists; Celiprolol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Propanolamines; Pulse; Random Allocation; Timolol | 1987 |
Comparison of topical timolol vs betaxolol on cardiopulmonary exercise performance in healthy volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Betaxolol; Clinical Trials as Topic; Exercise; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Random Allocation; Respiration; Timolol | 1988 |
Effect of topical timolol on the human retinal circulation.
Topics: Administration, Topical; Adolescent; Adult; Blood Pressure; Fundus Oculi; Humans; Intraocular Pressure; Regional Blood Flow; Retinal Vessels; Rheology; Timolol | 1986 |
A clinical trial of timolol and epinephrine in the treatment of primary open-angle glaucoma.
Topics: Aged; Chronic Disease; Clinical Trials as Topic; Epinephrine; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Prospective Studies; Random Allocation; Timolol | 1988 |
The 12-hour control of intraocular pressure on carteolol 2% twice daily.
Topics: Aged; Aged, 80 and over; Carteolol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1988 |
Levobunolol compared with timolol: a four-year study.
Topics: Aged; Blood Pressure; Double-Blind Method; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Timolol; Visual Fields | 1988 |
[Comparison of the effectiveness and safety of levobunolol and timolol in ocular hypertension and chronic open-angle glaucoma].
Topics: Adult; Aged; Aged, 80 and over; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Timolol | 1988 |
[Modification in amplitude of nycthemeral changes in intraocular pressure under timolol].
Topics: Adult; Circadian Rhythm; Female; Humans; Intraocular Pressure; Male; Timolol | 1988 |
The effect of long-term intraocular pressure reduction on the differential light sensitivity in glaucoma suspects.
Topics: Humans; Intraocular Pressure; Light; Ocular Hypertension; Regression Analysis; Time Factors; Timolol | 1988 |
The consensual ophthalmotonic reaction.
Topics: Adult; Aged; Aged, 80 and over; Epinephrine; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pilocarpine; Time Factors; Timolol | 1988 |
Sympathetic influences on the consensual ophthalmotonic reaction.
Topics: Aged; Female; Guanethidine; Horner Syndrome; Humans; Intraocular Pressure; Male; Middle Aged; Neurons, Efferent; Ocular Hypertension; Reflex; Sympathetic Nervous System; Time Factors; Timolol | 1988 |
A double-masked comparison of carteolol and timolol in ocular hypertension.
Topics: Administration, Topical; Ambulatory Care; Carteolol; Clinical Trials as Topic; Drug Administration Schedule; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Propanolamines; Timolol | 1988 |
Effect of changing medication regimens in glaucoma patients.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Patient Compliance; Timolol | 1988 |
[Effect of nonspecific and cardioselective beta receptor blockers on the formation of aqueous humor. An oculopressure tonometry study].
Topics: Adult; Betaxolol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Propanolamines; Timolol; Tonometry, Ocular | 1988 |
Use of an angiotensin converting enzyme inhibitor in ocular hypertension and primary open-angle glaucoma.
Topics: Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Phenylbutyrates; Pulse; Spiro Compounds; Time Factors; Timolol | 1988 |
A combination of levobunolol and dipivefrin for the treatment of glaucoma.
Topics: Drug Combinations; Epinephrine; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Optic Disk; Sleep Stages; Timolol; Visual Fields | 1988 |
Efficacy of twice-daily levobunolol in the treatment of elevated intraocular pressure.
Topics: Aged; Blood Pressure; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Timolol | 1988 |
The Lang lecture 1986. The enigma of primary open-angle glaucoma.
Topics: Adult; Aged; Clinical Trials as Topic; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Timolol; Visual Acuity; Visual Fields | 1986 |
Control of chronic simple glaucoma with primary medical, surgical and laser treatment.
Topics: Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Pilocarpine; Prospective Studies; Time Factors; Timolol; Trabecular Meshwork | 1986 |
A double-masked study of timolol and pilocarpine combined.
Topics: Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Pilocarpine; Timolol | 1987 |
Ocular and cardiovascular response to topical carteolol 2% and timolol 0.5% in healthy volunteers.
Topics: Adult; Blood Pressure; Cardiovascular System; Carteolol; Depression, Chemical; Double-Blind Method; Female; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Physical Exertion; Propanolamines; Timolol | 1988 |
[Effectiveness and tolerance of an active combination of timolol and pilocarpine--a pilot project].
Topics: Dose-Response Relationship, Drug; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Pilot Projects; Timolol | 1987 |
Influence of pindolol and timolol treatment on the visual fields of glaucoma patients.
Topics: Blood Pressure; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Pindolol; Prospective Studies; Timolol; Visual Fields | 1986 |
Betaxolol vs timolol. A six-month double-blind comparison.
Topics: Adult; Aged; Betaxolol; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1986 |
Levobunolol compared with timolol for the control of elevated intraocular pressure.
Topics: Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Ocular Hypertension; Timolol | 1986 |
Management of increased intraocular pressure after cataract extraction.
Topics: Cataract Extraction; Clinical Trials as Topic; Gels; Humans; Intraocular Pressure; Lenses, Intraocular; Ophthalmic Solutions; Pilocarpine; Postoperative Care; Random Allocation; Timolol | 1987 |
A comparison of the effects of oral nadolol and topical timolol on intraocular pressure, blood pressure, and heart rate.
Topics: Administration, Oral; Administration, Topical; Aged; Blood Pressure; Double-Blind Method; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Nadolol; Timolol | 1987 |
[Fluorophotometry by instillation. II. Effect of beta-blocker eyedrops in the normal subject].
Topics: Aqueous Humor; Fluorescein; Fluoresceins; Fluorometry; Humans; Instillation, Drug; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Placebos; Timolol | 1987 |
[Tolerance and pharmacologic effectiveness of antiglaucoma eyedrops].
Topics: Adult; Aged; Carteolol; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Propanolamines; Timolol | 1986 |
Sodium hyaluronate (Healon) in glaucoma filtering procedures.
Topics: Aged; Female; Glaucoma, Open-Angle; Gonioscopy; Humans; Hyaluronic Acid; Intraocular Pressure; Male; Middle Aged; Postoperative Complications; Prospective Studies; Random Allocation; Timolol; Trabecular Meshwork | 1986 |
Prevention of intraocular pressure elevation following neodymium-YAG laser posterior capsulotomy.
Topics: Aged; Evaluation Studies as Topic; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Lens, Crystalline; Middle Aged; Pilocarpine; Postoperative Care; Timolol | 1985 |
Primary therapy for chronic simple glaucoma the role of argon laser trabeculoplasty.
Topics: Aged; Chronic Disease; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Methods; Middle Aged; Pilocarpine; Random Allocation; Timolol; Trabecular Meshwork; Visual Acuity; Visual Fields | 1985 |
Levobunolol compared with timolol for the long-term control of elevated intraocular pressure.
Topics: Adult; Aged; Blood Pressure; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Timolol | 1985 |
Indomethacin does not attenuate the ocular hypotensive effect of timolol.
Topics: Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Interactions; Female; Humans; Indomethacin; Intraocular Pressure; Male; Timolol | 1985 |
Long-term ocular hypotensive effect of levobunolol: results of a one-year study.
Topics: Adult; Aged; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Random Allocation; Time Factors; Timolol | 1985 |
Timolol: long-term Canadian multicentre study.
Topics: Blood Pressure; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Pulse; Timolol | 1985 |
[Pressure lowering effect and side effects of 0.5% and 1.0% levobunolol eyedrops, compared with 0.5% timolol eyedrops in patients with open-angle glaucoma].
Topics: Dose-Response Relationship, Drug; Double-Blind Method; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ophthalmic Solutions; Random Allocation; Timolol | 1985 |
A study of the efficacy of two commercial preparations of timolol maleate with special reference to side effects.
Topics: Clinical Trials as Topic; Double-Blind Method; Female; Glaucoma; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Respiration Disorders; Timolol | 1985 |
Interaction of timolol and caffeine on intraocular pressure.
Topics: Adult; Caffeine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Timolol | 1985 |
Effect of topical indomethacin and timolol maleate on intraocular pressure in normal subjects.
Topics: Double-Blind Method; Humans; Indomethacin; Intraocular Pressure; Random Allocation; Timolol | 1985 |
664 other study(ies) available for timolol and Intraocular Pressure
| Article | Year |
|---|---|
Acetazolamide-like carbonic anhydrase inhibitors with topical ocular hypotensive activity.
Topics: Acetazolamide; Administration, Topical; Animals; Carbonic Anhydrase Inhibitors; Glaucoma; Intraocular Pressure; Male; Methazolamide; Rabbits; Structure-Activity Relationship | 1992 |
Improved delivery through biological membranes. 26. Design, synthesis, and pharmacological activity of a novel chemical delivery system for beta-adrenergic blocking agents.
Topics: Adrenergic beta-Antagonists; Animals; Heart Rate; Indicators and Reagents; Intraocular Pressure; Male; Propranolol; Rabbits; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Timolol | 1988 |
Novel class of LIM-kinase 2 inhibitors for the treatment of ocular hypertension and associated glaucoma.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Glaucoma; Guanidines; In Vitro Techniques; Intraocular Pressure; Lim Kinases; Mice; Nitriles; Ocular Hypertension; Piperazines; Pyrimidines; Pyrroles; Structure-Activity Relationship; Swine; Urea | 2009 |
New furoxan derivatives for the treatment of ocular hypertension.
Topics: Animals; Antihypertensive Agents; Disease Models, Animal; Glaucoma; Intraocular Pressure; Nitric Oxide; Ocular Hypertension; Oxadiazoles; Rabbits; Solubility; Timolol | 2017 |
Oxindole-based intraocular pressure reducing agents.
Topics: Crystallography, X-Ray; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Indoles; Intraocular Pressure; Ligands; Models, Molecular; Molecular Structure; Oxindoles; Quinone Reductases; Structure-Activity Relationship; Time Factors | 2017 |
Discovery of β-Adrenergic Receptors Blocker-Carbonic Anhydrase Inhibitor Hybrids for Multitargeted Antiglaucoma Therapy.
Topics: Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase II; Carbonic Anhydrase Inhibitors; Crystallography, X-Ray; Disease Models, Animal; Drug Design; Drug Evaluation, Preclinical; Glaucoma; Humans; Intraocular Pressure; Male; Molecular Targeted Therapy; Rabbits; Receptors, Adrenergic, beta; Structure-Activity Relationship | 2018 |
Morphological changes in the trabecular meshwork and Schlemm's canal after treatment with topical intraocular pressure-lowering agents.
Topics: Administration, Topical; Drug Combinations; Humans; Intraocular Pressure; Middle Aged; Prostaglandins, Synthetic; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Trabecular Meshwork | 2021 |
Beta-adrenergic glaucoma drugs reduce lymphatic clearance from the eye: A sequential photoacoustic imaging study.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Disease Models, Animal; Female; Glaucoma; Intraocular Pressure; Lymphatic Vessels; Male; Mice; Photoacoustic Techniques; Timolol | 2021 |
The use of fixed dose drug combinations for glaucoma in clinical settings: a retrospective, observational, single-centre study.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Retrospective Studies; Timolol | 2022 |
In Situ Gelling Electrospun Ocular Films Sustain the Intraocular Pressure-Lowering Effect of Timolol Maleate: In Vitro, Ex Vivo, and Pharmacodynamic Assessment.
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Animals; Chromatography, High Pressure Liquid; Cornea; Gels; Intraocular Pressure; Poloxamer; Polyvinyl Alcohol; Swine; Timolol | 2022 |
OCT ANGIOGRAPHY, VISUAL FIELD AND RNFL WITH VARIOUS MEDICATIONS IN HYPERTENSIVE GLAUCOMAS.
Topics: Angiography; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Timolol; Tomography, Optical Coherence; Visual Fields | 2021 |
Switching to Preservative-Free Tafluprost/Timolol Fixed-Dose Combination in the Treatment of Open-Angle Glaucoma or Ocular Hypertension: Subanalysis of Data from the VISIONARY Study According to Baseline Monotherapy Treatment.
Topics: Adult; Antihypertensive Agents; Bimatoprost; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prospective Studies; Prostaglandins A; Prostaglandins F; Timolol; Travoprost | 2022 |
Intraluminal deposits: A rare cause of glaucoma drainage implant total obstruction.
Topics: Glaucoma; Glaucoma Drainage Implants; Humans; Intraocular Pressure; Timolol | 2023 |
A comparison of country-level data from the VISIONARY study examining treatment outcomes with preservative-free tafluprost/timolol fixed-dose combination therapy.
Topics: Adrenergic beta-Antagonists; Adult; Antihypertensive Agents; Drug Combinations; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins A; Prostaglandins F; Timolol; Treatment Outcome | 2022 |
[Fixed combination of latanoprost and timolol in the long-term treatment of patients with normal-tension glaucoma].
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Low Tension Glaucoma; Ocular Hypertension; Prostaglandins F, Synthetic; Quality of Life; Timolol; Treatment Outcome | 2022 |
Reviewing the evidence surrounding preservative-free tafluprost/timolol fixed-dose combination therapy in open-angle glaucoma and ocular hypertension management: a focus on efficacy, safety, and tolerability.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Preservatives, Pharmaceutical; Timolol | 2022 |
Cationic liposomes as promising vehicles for timolol/brimonidine combination ocular delivery in glaucoma: formulation development and in vitro/in vivo evaluation.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Glaucoma; Intraocular Pressure; Liposomes; Polymers; Quinoxalines; Rabbits; Timolol | 2023 |
[Efficacy and safety of a fixed combination drug Brinzolol Duo in the treatment of patients with primary open-angle glaucoma].
Topics: Antihypertensive Agents; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Timolol; Treatment Outcome | 2022 |
A triple crosslinked micelle-hydrogel lacrimal implant for localized and prolonged therapy of glaucoma.
Topics: Animals; Antihypertensive Agents; Glaucoma; Hydrogels; Intraocular Pressure; Lacrimal Apparatus; Latanoprost; Micelles; Ocular Hypertension; Prostaglandins F, Synthetic; Quality of Life; Rabbits; Timolol; Treatment Outcome | 2023 |
Timolol-loaded ethosomes for ophthalmic delivery: Reduction of high intraocular pressure in vivo.
Topics: Adrenergic beta-Antagonists; Animals; Chickens; Female; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Pharmaceutical Preparations; Rats; Timolol | 2023 |
Primary Open-Angle Glaucoma Progression in Glaucoma Patients with Unchanged Topical Treatment over 3 Years - Retrospective Observational Cohort Analysis.
Topics: Administration, Topical; Antihypertensive Agents; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Retinal Ganglion Cells; Retrospective Studies; Timolol; Travoprost | 2023 |
RNA-seq analysis of human trabecular endothelial cells after treatment with timolol maleate.
Topics: Aqueous Humor; Endothelial Cells; Humans; Intraocular Pressure; RNA; Sequence Analysis, RNA; Timolol; Trabecular Meshwork | 2023 |
Additive effects of brimonidine tartrate 0.1%/brinzolamide 1% fixed-dose combination in prostaglandin analog-treated Japanese glaucoma patients.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; East Asian People; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Prostaglandins, Synthetic; Timolol | 2023 |
Efficacy of preserved Tafluprost 0.0015% in lowering intraocular pressure.
Topics: Antihypertensive Agents; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prostaglandins F; Retrospective Studies; Timolol; Treatment Outcome | 2023 |
[Pharmacogenetics of timolol].
Topics: Adrenergic beta-Antagonists; Humans; Intraocular Pressure; Pharmacogenetics; Timolol | 2019 |
Early weaning versus prolonged administration of aqueous suppressants for prevention of hyperencapsulation in paediatric Ahmed glaucoma valve.
Topics: Adolescent; Antihypertensive Agents; Child; Child, Preschool; Female; Follow-Up Studies; Glaucoma; Glaucoma Drainage Implants; Humans; Infant; Intraocular Pressure; Male; Ophthalmic Solutions; Postoperative Complications; Postoperative Period; Prospective Studies; Time Factors; Timolol; Treatment Outcome; Visual Acuity; Weaning | 2020 |
Prescribing Trends of Topical Glaucoma Medications in Australia From 2001 to 2017.
Topics: Administration, Ophthalmic; Adrenergic Agonists; Antihypertensive Agents; Australia; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Drug Prescriptions; Drug Therapy, Combination; Drug Utilization; Glaucoma, Open-Angle; Health Services Research; Health Surveys; Humans; Intraocular Pressure; Ophthalmic Solutions; Practice Patterns, Physicians'; Sulfonamides; Thiazines; Timolol | 2020 |
Ocular Intracameral Pharmacokinetics for a Cocktail of Timolol, Betaxolol, and Atenolol in Rabbits.
Topics: Adrenergic beta-1 Receptor Antagonists; Animals; Aqueous Humor; Atenolol; Betaxolol; Chromatography, Liquid; Drug Combinations; Half-Life; Injections, Intraocular; Intraocular Pressure; Male; Metabolic Clearance Rate; Rabbits; Tandem Mass Spectrometry; Timolol; Tissue Distribution | 2020 |
Comparison of Two Combinations of Maximum Medical Therapy for Lowering Intraocular Pressure in Primary Open-angle Glaucoma.
Topics: Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2020 |
Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: The VISIONARY Study.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Prospective Studies; Prostaglandins F; Prostaglandins, Synthetic; Timolol; Tonometry, Ocular | 2020 |
Reduction of intraocular pressure using timolol orally dissolving strips in the treatment of induced primary open-angle glaucoma in rabbits.
Topics: Administration, Oral; Animals; Antihypertensive Agents; Biological Availability; Drug Compounding; Drug Delivery Systems; Drug Liberation; Drug Stability; Glaucoma, Open-Angle; In Vitro Techniques; Intraocular Pressure; Oxidative Stress; Polymers; Rabbits; Timolol | 2020 |
Reversible Corneal Endothelial Abnormalities With Netarsudil.
Topics: Aged; Antihypertensive Agents; Benzoates; beta-Alanine; Corneal Diseases; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Remission Induction; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Withholding Treatment | 2020 |
[Effectiveness of antihypertensive conservative-free therapy with fixed combination of bimatoprost and timolol (intermediate results)].
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Timolol; Treatment Outcome | 2020 |
European real-world data about the use of a new delivery system containing a preservative-free multi-dose glaucoma treatment.
Topics: Adult; Antihypertensive Agents; Child; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Treatment Outcome | 2021 |
Multiple drug delivery from the drug-implants-laden silicone contact lens: Addressing the issue of burst drug release.
Topics: Animals; Bimatoprost; Contact Lenses; Drug Carriers; Drug Implants; Drug Liberation; Hyaluronic Acid; Intraocular Pressure; Rabbits; Silicones; Surface Properties; Timolol | 2020 |
Effects of topical administration of tafluprost and combination of tafluprost and timolol or tafluprost and betaxolol on Schirmer tear test, intraocular pressure, and pupil size in clinically healthy dogs.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Betaxolol; Dogs; Intraocular Pressure; Male; Prostaglandins F; Pupil; Timolol | 2020 |
Persistence and treatment patterns of fixed combination drugs for glaucoma: a retrospective claims database study in Japan.
Topics: Adult; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Databases, Factual; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Insurance, Health, Reimbursement; Intraocular Pressure; Japan; Male; Medication Adherence; Middle Aged; Ocular Hypertension; Prostaglandins, Synthetic; Retrospective Studies; Timolol; Universal Health Insurance | 2020 |
[Combined laser treatment of glaucoma].
Topics: Antihypertensive Agents; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Timolol; Tonometry, Ocular; Trabeculectomy; Treatment Outcome | 2020 |
Topical timolol for the treatment of conjunctival pyogenic granulomas: Outcomes and effect on intraocular pressure.
Topics: Adult; Antihypertensive Agents; Double-Blind Method; Granuloma, Pyogenic; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Tonometry, Ocular | 2020 |
Effect of surfactant concentration and sterilization process on intraocular pressure-lowering activity of Δ
Topics: Animals; Antihypertensive Agents; Dronabinol; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sterilization; Surface-Active Agents; Timolol; Valine | 2021 |
Mucoadhesive and responsive nanogels as carriers for sustainable delivery of timolol for glaucoma therapy.
Topics: Antihypertensive Agents; Drug Delivery Systems; Glaucoma; Humans; Intraocular Pressure; Nanogels; Timolol | 2021 |
Comparative evaluation of Latanoprostene Bunod, Timolol Maleate, and latanoprost Ophthalmic Solutions to assess their safety and efficacy in lowering intraocular pressure for the management of Open-Angle Glaucoma.
Topics: Antihypertensive Agents; Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2020 |
[Development of additive systemic effects when taking β-blockers in patients with glaucoma and concurrent chronic diseases].
Topics: Adrenergic beta-Antagonists; Chronic Disease; Glaucoma; Humans; Intraocular Pressure; Timolol | 2020 |
Efficacy and safety of fixed-combination brimonidine tartrate/timolol maleate in primary open-angle glaucoma, including normal-tension glaucoma.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Prospective Studies; Timolol; Treatment Outcome | 2021 |
Netarsudil-related Eyelid Wound Dehiscence.
Topics: Aged, 80 and over; Antihypertensive Agents; Benzoates; beta-Alanine; Eyelids; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Timolol | 2021 |
Treatment of Open-Angle Glaucoma and Ocular Hypertension with Preservative-Free Tafluprost/Timolol Fixed-Dose Combination Therapy: UK and Ireland Results from the VISIONARY Study.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ireland; Ocular Hypertension; Prospective Studies; Prostaglandins F; Timolol; United Kingdom | 2021 |
Lollipop-Inspired Multilayered Drug Delivery Hydrogel for Dual Effective, Long-Term, and NIR-Defined Glaucoma Treatment.
Topics: Animals; Drug Delivery Systems; Glaucoma; Humans; Hydrogels; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Spectroscopy, Near-Infrared; Timolol | 2021 |
Ocular Cubosome Drug Delivery System for Timolol Maleate: Preparation, Characterization, Cytotoxicity, Ex Vivo, and In Vivo Evaluation.
Topics: Administration, Ophthalmic; Adrenergic beta-Antagonists; Animals; Cornea; Drug Delivery Systems; Drug Evaluation, Preclinical; Female; Humans; Intraocular Pressure; Ophthalmic Solutions; Particle Size; Rabbits; Scattering, Small Angle; Timolol; X-Ray Diffraction | 2017 |
The role of hyaluronan as a drug carrier to enhance the bioavailability of extended release ophthalmic formulations. Hyaluronan-timolol ionic complexes as a model case.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Biological Availability; Cornea; Delayed-Action Preparations; Drug Carriers; Drug Liberation; Hyaluronic Acid; Intraocular Pressure; Ophthalmic Solutions; Permeability; Rabbits; Timolol | 2017 |
Long term safety and tolerability of Tafluprost 0.0015% vs Timolol 0.1% preservative-free in ocular hypertensive and in primary open-angle glaucoma patients: a cross sectional study.
Topics: Aged; Antihypertensive Agents; Cross-Sectional Studies; Dose-Response Relationship, Drug; Drug Tolerance; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Microscopy, Confocal; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Tears; Time Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2017 |
Evaluation of the anti-Acanthamoeba activity of two commercial eye drops commonly used to lower eye pressure.
Topics: Acanthamoeba; Acanthamoeba Keratitis; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Analysis of Variance; Apoptosis; Brimonidine Tartrate; Brimonidine Tartrate, Timolol Maleate Drug Combination; Glaucoma; Inhibitory Concentration 50; Intraocular Pressure; Membrane Potential, Mitochondrial; Ophthalmic Solutions; Timolol | 2017 |
Pure Glaucoma Drugs Are Toxic to Immortalized Human Corneal Epithelial Cells, but They Do Not Destabilize Lipid Membranes.
Topics: Antihypertensive Agents; Apoptosis; Brimonidine Tartrate; Cell Line; Cell Membrane; Cell Survival; Electrophoresis, Capillary; Epithelium, Corneal; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Liposomes; Membrane Lipids; Ocular Hypertension; Pilocarpine; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol | 2017 |
Co-instillation of nano-solid magnesium hydroxide enhances corneal permeability of dissolved timolol.
Topics: Animals; Antihypertensive Agents; Biological Availability; Cornea; Disease Models, Animal; Glaucoma; Intraocular Pressure; Magnesium Hydroxide; Nanoparticles; Permeability; Rabbits; Rats; Timolol | 2017 |
Isotretinoin-induced Angle Closure and Myopic Shift.
Topics: Acne Vulgaris; Adult; Antihypertensive Agents; Dermatologic Agents; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Isotretinoin; Microscopy, Acoustic; Myopia; Sulfonamides; Thiophenes; Timolol | 2017 |
Effect of Cromakalim Prodrug 1 (CKLP1) on Aqueous Humor Dynamics and Feasibility of Combination Therapy With Existing Ocular Hypotensive Agents.
Topics: Amides; Animals; Anterior Eye Segment; Antihypertensive Agents; Aqueous Humor; Cromakalim; Drug Synergism; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Latanoprost; Male; Mice; Mice, Inbred C57BL; Middle Aged; Ophthalmic Solutions; Prodrugs; Prostaglandins F, Synthetic; Pyridines; Rabbits; Sclera; Timolol; Tonometry, Ocular; Venous Pressure | 2017 |
Self-Assembling Elastin-Like Hydrogels for Timolol Delivery: Development of an Ophthalmic Formulation Against Glaucoma.
Topics: Animals; Antihypertensive Agents; Calorimetry, Differential Scanning; Cell Line; Drug Carriers; Drug Liberation; Elastin; Eye; Fibroblasts; Glaucoma; Humans; Hydrogels; Intraocular Pressure; Male; Models, Animal; Ophthalmic Solutions; Rabbits; Rheology; Silk; Timolol; Treatment Outcome | 2017 |
Mirtogenol® supplementation in association with dorzolamide-timolol or latanoprost improves the retinal microcirculation in asymptomatic patients with increased ocular pressure.
Topics: Administration, Ophthalmic; Adult; Antihypertensive Agents; Blood Flow Velocity; Drug Combinations; Female; Flavonoids; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Microcirculation; Middle Aged; Oxidative Stress; Prostaglandins F, Synthetic; Retina; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2017 |
Changes in Ocular Hemodynamics after Carotid Artery Angioplasty and Stenting (CAAS) in Patients with Different Severity of Ocular Ischemic Syndrome.
Topics: Adrenergic beta-Antagonists; Aged; Angioplasty, Balloon; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Carotid Artery, Internal; Carotid Stenosis; Drug Therapy, Combination; Eye; Female; Humans; Intraocular Pressure; Iris; Ischemia; Laser Coagulation; Male; Neovascularization, Pathologic; Ophthalmic Artery; Prospective Studies; Retinal Vessels; Stents; Sulfonamides; Thiazines; Timolol; Ultrasonography, Doppler, Color; Visual Acuity | 2018 |
Sustained release timolol maleate loaded ocusert based on biopolymer composite.
Topics: Animals; Delayed-Action Preparations; Glaucoma; Goats; Intraocular Pressure; Pilocarpine; Rabbits; Timolol | 2018 |
Eye Drop Dispenser Type and Medication Possession Ratio in Patients With Glaucoma: Single-Use Containers Versus Multiple-Use Bottles.
Topics: Administration, Ophthalmic; Aged; Antihypertensive Agents; Drug Combinations; Drug Packaging; Drug Utilization; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
Meibomian Gland Features and Conjunctival Goblet Cell Density in Glaucomatous Patients Controlled With Prostaglandin/Timolol Fixed Combinations: A Case Control, Cross-sectional Study.
Topics: Aged; Antihypertensive Agents; Bimatoprost; Case-Control Studies; Cell Count; Conjunctiva; Cross-Sectional Studies; Drug Combinations; Female; Glaucoma; Goblet Cells; Humans; Intraocular Pressure; Latanoprost; Male; Meibomian Glands; Microscopy, Confocal; Middle Aged; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular; Travoprost | 2018 |
Peyronie's disease and Dupuytren's contracture secondary to topical timolol.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Dupuytren Contracture; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Penile Induration; Timolol | 2019 |
Coincident cataract and glaucoma surgery in an anticoagulated patient: January consultation #1.
Topics: Aged; Anticoagulants; Antihypertensive Agents; Bimatoprost; Cardiovascular Diseases; Cataract; Cataract Extraction; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Timolol; Trabeculectomy; Visual Acuity; Visual Field Tests; Visual Fields; Warfarin | 2018 |
Association of Postoperative Topical Prostaglandin Analog or Beta-Blocker Use and Incidence of Pseudophakic Cystoid Macular Edema.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Bimatoprost; Case-Control Studies; Cataract; Cataract Extraction; Combined Modality Therapy; Female; Humans; Incidence; Intraocular Pressure; Latanoprost; Macular Edema; Male; Middle Aged; Postoperative Complications; Postoperative Period; Prostaglandins, Synthetic; Pseudophakia; Timolol; Travoprost | 2018 |
Exploring gelatin nanoparticles as novel nanocarriers for Timolol Maleate: Augmented in-vivo efficacy and safe histological profile.
Topics: Administration, Ophthalmic; Animals; Antihypertensive Agents; Cross-Linking Reagents; Drug Carriers; Drug Compounding; Drug Liberation; Drug Stability; Gelatin; Glutaral; Intraocular Pressure; Microscopy, Electron, Transmission; Nanoparticles; Nanotechnology; Particle Size; Rabbits; Solubility; Technology, Pharmaceutical; Time Factors; Timolol | 2018 |
Effectiveness and safety of switching from prostaglandin analog monotherapy to prostaglandin/timolol fixed combination therapy or adding ripasudil.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Substitution; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Isoquinolines; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Prostaglandins F, Synthetic; rho-Associated Kinases; Sulfonamides; Timolol; Treatment Outcome | 2018 |
TOPICAL DORZOLAMIDE-TIMOLOL WITH INTRAVITREOUS ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR FOR RETINAL VEIN OCCLUSION: A PILOT STUDY.
Topics: Administration, Ophthalmic; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Bevacizumab; Drug Combinations; Drug Therapy, Combination; Female; Fovea Centralis; Humans; Intraocular Pressure; Intravitreal Injections; Macular Edema; Male; Middle Aged; Ophthalmic Solutions; Pilot Projects; Ranibizumab; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Retinal Vein Occlusion; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Vascular Endothelial Growth Factor A; Visual Acuity | 2021 |
Acute angle closure following hemodialysis in a 34-year-old Nigerian female.
Topics: Adult; Drug Combinations; Female; Glaucoma; Glaucoma, Angle-Closure; Glomerulonephritis; Gonioscopy; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Renal Dialysis; Renal Insufficiency, Chronic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome; Visual Acuity | 2018 |
Referral for first glaucoma surgery in Europe, the ReF-GS study.
Topics: Adrenergic beta-Antagonists; Aged; Carbonic Anhydrase Inhibitors; Disease Progression; European Union; Exfoliation Syndrome; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Referral and Consultation; Surveys and Questionnaires; Timolol; Trabeculectomy | 2019 |
In Reply: Meibomian Gland Features and Conjunctival Goblet Cell Density in Glaucomatous Patients Controlled With Prostaglandin/Timolol Fixed Combinations: A Case Control, Cross-sectional Study.
Topics: Cell Count; Cross-Sectional Studies; Humans; Intraocular Pressure; Meibomian Glands; Prostaglandins; Timolol | 2018 |
Meibomian Gland Features and Conjunctival Goblet Cell Density in Glaucomatous Patients Controlled With Prostaglandin/Timolol-fixed Combinations: A Case Control, Cross-sectional Study.
Topics: Cell Count; Cross-Sectional Studies; Humans; Intraocular Pressure; Meibomian Glands; Prostaglandins; Timolol | 2018 |
A Worldwide Price Comparison of Glaucoma Medications, Laser Trabeculoplasty, and Trabeculectomy Surgery.
Topics: Administration, Ophthalmic; Antihypertensive Agents; Costs and Cost Analysis; Cross-Sectional Studies; Drug Costs; Female; Glaucoma; Global Health; Health Services Accessibility; Humans; Income; Intraocular Pressure; Laser Coagulation; Latanoprost; Male; Middle Aged; Timolol; Trabeculectomy | 2018 |
Is the Use of Refrigerated Fixed Combination of Dorzolamide 2%-Timolol 0.5% (COSOPT) Associated with Less Ocular Discomfort: A Pilot Study.
Topics: Antihypertensive Agents; Drug Combinations; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Prospective Studies; Sulfonamides; Thiophenes; Timolol | 2018 |
Gelatinized core liposomes: A new Trojan horse for the development of a novel timolol maleate glaucoma medication.
Topics: Adrenergic beta-Antagonists; Animals; Chemistry, Pharmaceutical; Cornea; Delayed-Action Preparations; Disease Models, Animal; Drug Liberation; Drug Stability; Gelatin; Glaucoma; Hydrophobic and Hydrophilic Interactions; Intraocular Pressure; Liposomes; Particle Size; Rabbits; Timolol | 2019 |
Consultation Section: Glaucoma. Management of cataract and glaucoma in patient with a preexisting Cypass microstent in fellow eye: January consultation #1.
Topics: Aged; Antihypertensive Agents; Cataract; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Optic Disk; Referral and Consultation; Retinal Pigment Epithelium; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Fields | 2019 |
Comparison of Fellow Eyes of Acute Primary Angle Closure and Phacomorphic Angle Closure.
Topics: Acetazolamide; Acute Disease; Administration, Ophthalmic; Adult; Aged; Anterior Eye Segment; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cross-Sectional Studies; Diuretics, Osmotic; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Infusions, Intravenous; Intraocular Pressure; Lens Diseases; Male; Mannitol; Middle Aged; Prospective Studies; Timolol; Tomography, Optical Coherence | 2019 |
Co-Delivery of Timolol and Brimonidine with a Polymer Thin-Film Intraocular Device.
Topics: Animals; Brimonidine Tartrate; Chromatography, Liquid; Drug Delivery Systems; Female; Hydrogen-Ion Concentration; Intraocular Pressure; Kinetics; Male; Ophthalmic Solutions; Polyesters; Rabbits; Tandem Mass Spectrometry; Temperature; Timolol | 2019 |
Effect of gold nanoparticles on timolol uptake and its release kinetics from contact lenses: In vitro and in vivo evaluation.
Topics: Animals; Contact Lenses; Drug Liberation; Eye; Gold; Intraocular Pressure; Kinetics; Metal Nanoparticles; Rabbits; Timolol; Tissue Distribution | 2019 |
Effect of Timolol on Aqueous Humor Outflow Facility in Healthy Human Eyes.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Aqueous Humor; Female; Fluorophotometry; Gonioscopy; Healthy Volunteers; Humans; Instillation, Drug; Intraocular Pressure; Male; Middle Aged; Prospective Studies; Timolol; Tonometry, Ocular; Trabecular Meshwork | 2019 |
Patient Preference-Based Comparative Effectiveness and Cost-Utility Analysis of the Prostamides for Open-Angle Glaucoma.
Topics: Bimatoprost; Cost-Benefit Analysis; Glaucoma, Open-Angle; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Patient Preference; Prostaglandins F; Timolol; Travoprost; Visual Acuity | 2019 |
Glaucoma in Phacomatosis Pigmentovascularis in a Young African Adolescent Boy: A Case Report.
Topics: Adolescent; Antihypertensive Agents; Black People; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Male; Nerve Fibers; Neurocutaneous Syndromes; Nevus of Ota; Optic Disk; Port-Wine Stain; Retinal Ganglion Cells; South Africa; Timolol; Tomography, Optical Coherence; Ultrasonography | 2019 |
Efficacy and safety of the fixed combinations of tafluprost/timolol and latanoprost/carteolol.
Topics: Animals; Antihypertensive Agents; Carteolol; Cell Line; Drug Combinations; Epithelium, Corneal; Humans; Intraocular Pressure; Latanoprost; Macaca fascicularis; Male; Prostaglandins F; Timolol | 2019 |
Co-delivery of latanoprost and timolol from micelles-laden contact lenses for the treatment of glaucoma.
Topics: Animals; Antihypertensive Agents; Contact Lenses; Drug Carriers; Drug Combinations; Drug Delivery Systems; Glaucoma; Intraocular Pressure; Latanoprost; Male; Micelles; Polyethylene Glycols; Polyglutamic Acid; Rabbits; Timolol | 2019 |
Comparison of different combinations of maximum medical therapy for lowering intraocular pressure in primary open angle glaucoma: 12-month retrospective consecutive case series.
Topics: Aged; Antihypertensive Agents; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Dose-Response Relationship, Drug; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiazines; Time Factors; Timolol; Treatment Outcome | 2019 |
Efficacy of Topical Timolol Eye Drops for the Treatment of Diabetic Macular Edema.
Topics: Adrenergic beta-Antagonists; Diabetic Retinopathy; Follow-Up Studies; Humans; Intraocular Pressure; Macula Lutea; Macular Edema; Ophthalmic Solutions; Prospective Studies; Timolol; Tomography, Optical Coherence; Treatment Outcome; Visual Acuity | 2019 |
[Initial combination therapy for primary open-angle glaucoma].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2019 |
Effect of topical glaucoma medication on tear lipid layer thickness in patients with unilateral glaucoma.
Topics: Administration, Ophthalmic; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Cross-Sectional Studies; Drug Combinations; Dry Eye Syndromes; Female; Gonioscopy; Humans; Interferometry; Intraocular Pressure; Lipid Metabolism; Low Tension Glaucoma; Male; Meibomian Gland Dysfunction; Middle Aged; Ophthalmic Solutions; Sulfonamides; Tears; Thiophenes; Timolol; Tonometry, Ocular | 2019 |
Effect of Dorzolamide/Timolol or Brinzolamide/Timolol prophylaxis on intravitreal anti-VEGF injection-induced intraocular hypertension.
Topics: Administration, Topical; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antihypertensive Agents; Bevacizumab; Drug Therapy, Combination; Female; Humans; Intraocular Pressure; Intravitreal Injections; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prospective Studies; Ranibizumab; Retinal Diseases; Sulfonamides; Thiazines; Thiophenes; Timolol; Tonometry, Ocular; Vascular Endothelial Growth Factor A | 2013 |
Crystallins are regulated biomarkers for monitoring topical therapy of glaucomatous optic neuropathy.
Topics: Animals; Biomarkers; Crystallins; Disease Models, Animal; Drug Combinations; Gene Expression Profiling; Gene Expression Regulation; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Optic Nerve Diseases; Proteome; Proteomics; Rats; Real-Time Polymerase Chain Reaction; Retina; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Timolol | 2013 |
Comparison of trabeculectomy with mitomycin-C versus medical treatment in moderate stage of steroid induced glaucoma.
Topics: Administration, Topical; Adolescent; Adult; Alkylating Agents; Child; Combined Modality Therapy; Female; Glaucoma; Humans; Intraocular Pressure; Male; Mitomycin; Prospective Studies; Steroids; Timolol; Trabeculectomy; Visual Acuity | 2013 |
Novel usage of intraocular pressure-lowering drugs as wound-healing inhibitors after trabeculectomy with cell culture and animal models.
Topics: Animals; Aqueous Humor; Benzalkonium Compounds; Biomarkers; Cell Culture Techniques; Cell Movement; Cell Proliferation; Collagen; Dinoprost; Fibroblasts; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Proliferating Cell Nuclear Antigen; Prostaglandins F, Synthetic; Rabbits; Timolol; Trabeculectomy; Wound Healing | 2013 |
[Contribution focused to clarify correlation between mixtures of the free amino acids with antiglaucomatics in influencing the IOP in rabbits after application into the conjunctival sac].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2013 |
A decrease of the rabbit's physiologic IOP after the application of specific amino acids and double combination of antiglaucomatics mixture.
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Taurine; Thiophenes; Timolol | 2013 |
Suspected granulomatous anterior uveitis associated with brimonidine tartrate 0.2% and timolol maleate 0.5% ophthalmic solution.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Granuloma; Humans; Intraocular Pressure; Ophthalmic Solutions; Quinoxalines; Timolol; Uveitis, Anterior | 2013 |
Novel bioadhesive hyaluronan-itaconic acid crosslinked films for ocular therapy.
Topics: Adhesiveness; Administration, Ophthalmic; Animals; Antihypertensive Agents; Cell Line; Cell Proliferation; Cell Survival; Drug Delivery Systems; Epoxy Resins; Glutaral; Humans; Hyaluronic Acid; Intraocular Pressure; Rabbits; Succinates; Timolol | 2013 |
Physicochemical and pharmacological investigation of water/oil microemulsion of non-selective beta blocker for treatment of glaucoma.
Topics: Adrenergic beta-Antagonists; Animals; Biological Availability; Colloids; Cornea; Disease Models, Animal; Drug Delivery Systems; Electric Capacitance; Emulsions; Glaucoma; Goats; Intraocular Pressure; Oils; Particle Size; Polysorbates; Rabbits; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents; Timolol; Water | 2014 |
Comment on "Effect of dacryocystorhinostomy on systemic adverse effects of topical timolol maleate".
Topics: Adrenergic beta-Antagonists; Dacryocystorhinostomy; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Timolol | 2013 |
[Signs and symptoms of ocular surface disease in patients on topical intraocular pressure-lowering therapy].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blepharitis; Cornea; Cross-Sectional Studies; Female; Fluorescein; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Keratitis; Lacrimal Apparatus Diseases; Male; Microscopy, Acoustic; Middle Aged; Ocular Hypertension; Severity of Illness Index; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Young Adult | 2013 |
Hemorrhagic choroidal detachment after use of anti-glaucomatous eye drops: case report.
Topics: Aged, 80 and over; Antihypertensive Agents; Choroid; Choroid Hemorrhage; Cloprostenol; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Timolol; Travoprost; Ultrasonography | 2013 |
Improvement in glaucoma patient quality of life by therapy switch to preservative-free timolol/dorzolamide fixed combination.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Drug Substitution; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Preservatives, Pharmaceutical; Prospective Studies; Quality of Life; Sickness Impact Profile; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol; Visual Acuity | 2014 |
Ocular surface changes in glaucomatous patients treated with and without preservatives beta-blockers.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Dry Eye Syndromes; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Middle Aged; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Quality of Life; Surveys and Questionnaires; Timolol | 2014 |
Managing advanced unilateral pseudoexfoliative glaucoma.
Topics: Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Hypertrichosis; Intraocular Pressure; Iris Diseases; Latanoprost; Male; Middle Aged; Pigmentation Disorders; Prostaglandins F, Synthetic; Sulfonamides; Thiazines; Timolol; Trabeculectomy | 2014 |
Early and frequent development of ocular hypertension in children with nephrotic syndrome.
Topics: Adolescent; Adrenergic beta-Antagonists; Anti-Inflammatory Agents; Antihypertensive Agents; Child; Child, Preschool; Cohort Studies; Female; Humans; Infant; Intraocular Pressure; Latanoprost; Male; Nephrotic Syndrome; Ocular Hypertension; Ophthalmic Solutions; Prednisolone; Prevalence; Prostaglandins F, Synthetic; Recurrence; Retrospective Studies; Timolol | 2014 |
Anterior and posterior segment changes in rat eyes with chronic steroid administration and their responsiveness to antiglaucoma drugs.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Catalase; Dexamethasone; Disease Models, Animal; Female; Glutathione; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Oxidative Stress; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Rats, Sprague-Dawley; Retina; Sulfonamides; Superoxide Dismutase; Thiophenes; Timolol | 2015 |
Vitrectomy without gas tamponade for macular retinoschisis associated with normal-tension glaucoma.
Topics: Coloring Agents; Endotamponade; Female; Fluorescein Angiography; Humans; Indocyanine Green; Intraocular Pressure; Low Tension Glaucoma; Middle Aged; Ophthalmic Solutions; Retinoschisis; Timolol; Tomography, Optical Coherence; Visual Acuity; Visual Field Tests; Vitrectomy | 2015 |
Liposome incorporated ion sensitive in situ gels for opthalmic delivery of timolol maleate.
Topics: Administration, Ophthalmic; Animals; Antihypertensive Agents; Cornea; Drug Delivery Systems; Female; Gels; Hydrogen-Ion Concentration; Intraocular Pressure; Liposomes; Male; Ophthalmic Solutions; Permeability; Polysaccharides, Bacterial; Rabbits; Time Factors; Timolol | 2015 |
Diadenosine tetraphosphate improves adrenergic anti-glaucomatous drug delivery and efficiency.
Topics: Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Aqueous Humor; Blotting, Western; Brimonidine Tartrate; Cell Membrane Permeability; Cells, Cultured; Dinucleoside Phosphates; Drug Delivery Systems; Electric Impedance; Epithelium, Corneal; Glaucoma; Humans; Intraocular Pressure; Male; Occludin; Quinoxalines; Rabbits; Tight Junctions; Timolol; Zonula Occludens-1 Protein | 2015 |
Angle closure secondary to the use of lorazepam in patient with myopia magna.
Topics: Acetazolamide; Cholinergic Antagonists; Combined Modality Therapy; Depression; Dexamethasone; Disease Susceptibility; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Lorazepam; Mydriatics; Myopia; Timolol; Tomography, Optical Coherence; Visual Field Tests; Young Adult | 2015 |
Crosslinked soy protein films and their application as ophthalmic drug delivery system.
Topics: Animals; Antihypertensive Agents; Cross-Linking Reagents; Delayed-Action Preparations; Diffusion; Gastrointestinal Agents; Intraocular Pressure; Materials Testing; Membranes, Artificial; Ophthalmic Solutions; Rabbits; Soybean Proteins; Timolol | 2015 |
The fixed combination efficacy assessment in patients with secondary neovascular glaucoma and diabetes mellitus.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Amides; Cloprostenol; Diabetic Angiopathies; Drug Combinations; Drug Substitution; Female; Glaucoma, Neovascular; Humans; Intraocular Pressure; Male; Middle Aged; Timolol; Treatment Outcome | 2015 |
Dual drug delivery from vitamin E loaded contact lenses for glaucoma therapy.
Topics: Animals; Antihypertensive Agents; Biological Availability; Contact Lenses; Delayed-Action Preparations; Dogs; Drug Liberation; Drug Therapy, Combination; Glaucoma, Open-Angle; Heart Rate; Intraocular Pressure; Ophthalmic Solutions; Sulfonamides; Thiophenes; Timolol; Vitamin E | 2015 |
A biodegradable ocular implant for long-term suppression of intraocular pressure.
Topics: Absorbable Implants; Animals; Antihypertensive Agents; Delayed-Action Preparations; Drug Delivery Systems; Drug Liberation; Intraocular Pressure; Macaca fascicularis; Ocular Hypertension; Polymers; Timolol | 2015 |
In Vitro Effects of Anti-Glaucomatous Eye Drops on Platelet-Activating Factor and its Metabolism.
Topics: Animals; Disease Models, Animal; Drug Combinations; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Platelet Activating Factor; Platelet Aggregation; Rabbits; Sulfonamides; Thiophenes; Timolol | 2017 |
Benefits of Tafluprost and Timolol Fixed-Dose Combination for the Treatment of Glaucoma Are Confirmed by Studies on Experimental Animal Models.
Topics: Administration, Ophthalmic; Animals; Antihypertensive Agents; Aqueous Humor; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Macaca fascicularis; Male; Ocular Hypertension; Prostaglandins F; Rats; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Timolol | 2015 |
The effect of prophylactic topical carbonic anhydrase inhibitors in canine primary closed-angle glaucoma.
Topics: Administration, Ophthalmic; Animals; Carbonic Anhydrase Inhibitors; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Glaucoma, Angle-Closure; Intraocular Pressure; Male; Retrospective Studies; Sulfonamides; Thiazines; Thiophenes; Timolol | 2015 |
Comparison of Ocular Pulse Amplitude Lowering Effects of Preservative-Free Tafluprost and Preservative-Free Dorzolamide-Timolol Fixed Combination Eyedrops.
Topics: Drug Combinations; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2015 |
Secondary pigmentary glaucoma associated with 1-piece foldable intraocular lens in the ciliary sulcus.
Topics: Aged, 80 and over; Antihypertensive Agents; Ciliary Body; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Lenses, Intraocular; Male; Phacoemulsification; Prosthesis Design; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Tonometry, Ocular; Visual Acuity | 2015 |
Evaluation of Efficacy and Safety of Latanoprost/Timolol versus Travoprost/Timolol Fixed Combinations for Ocular Hypertension Associated with Uveitis.
Topics: Antihypertensive Agents; Drug Combinations; Female; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Retrospective Studies; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Uveitis | 2017 |
Strategies to estimate the characteristics of 24-hour IOP curves of treated glaucoma patients during office hours.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Office Visits; Physicians' Offices; Posture; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 2016 |
In vitro and in vivo evaluation of novel implantation technology in hydrogel contact lenses for controlled drug delivery.
Topics: Animals; Antihypertensive Agents; Contact Lenses; Delayed-Action Preparations; Drug Delivery Systems; Equipment Design; Female; Glaucoma; Hydrogel, Polyethylene Glycol Dimethacrylate; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Timolol | 2016 |
Efficacy of Bimatoprost Plus Timolol Fixed Combination in Open Angle Glaucoma Patients Previously Treated with Dorzolamide Plus Timolol Fixed Combination.
Topics: Aged; Antihypertensive Agents; Bimatoprost; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Retrospective Studies; Sulfonamides; Thiophenes; Time Factors; Timolol; Treatment Outcome | 2016 |
In vitro and in vivo corneal effects of latanoprost combined with brimonidine, timolol, dorzolamide, or brinzolamide.
Topics: Animals; Brimonidine Tartrate; Cell Survival; Electric Impedance; Epithelium, Corneal; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Prostaglandins F, Synthetic; Rabbits; Safety; Sulfonamides; Thiazines; Thiophenes; Timolol | 2016 |
Advantages of Efficacy and Safety of Fixed-Dose Tafluprost/Timolol Combination Over Fixed-Dose Latanoprost/Timolol Combination.
Topics: Animals; Antihypertensive Agents; Area Under Curve; Cell Line; Chromatography, Liquid; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Macaca fascicularis; Male; Metabolic Clearance Rate; Ocular Hypertension; Prostaglandins F; Prostaglandins F, Synthetic; Rats, Sprague-Dawley; Tandem Mass Spectrometry; Time Factors; Timolol; Treatment Outcome | 2016 |
Bioadhesive chitosan-loaded liposomes: A more efficient and higher permeable ocular delivery platform for timolol maleate.
Topics: Animals; Antihypertensive Agents; Chitosan; Drug Evaluation, Preclinical; Drug Liberation; Intraocular Pressure; Liposomes; Male; Ocular Hypertension; Particle Size; Permeability; Rabbits; Timolol; Tissue Distribution | 2017 |
Impact of Combination Glaucoma Therapies on β-Blocker Exposure.
Topics: Adrenergic beta-Antagonists; Aged; Betaxolol; Drug Combinations; Drug Prescriptions; Drug Utilization; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Timolol | 2017 |
Development of Timolol-Loaded Galactosylated Chitosan Nanoparticles and Evaluation of Their Potential for Ocular Drug Delivery.
Topics: Animals; Antihypertensive Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Chitosan; Cornea; Drug Delivery Systems; Intraocular Pressure; Nanoparticles; Particle Size; Rabbits; Timolol | 2017 |
Effect of prophylactic topical hypotensive medications in reducing the incidence of postoperative ocular hypertension after phacoemulsification in dogs.
Topics: Administration, Topical; Animals; Dog Diseases; Dogs; Female; Incidence; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Ophthalmic Solutions; Phacoemulsification; Postoperative Complications; Pre-Exposure Prophylaxis; Prostaglandins F, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol | 2017 |
Evaluation of retinal ganglion cell function after intraocular pressure reduction measured by pattern electroretinogram in patients with primary open-angle glaucoma.
Topics: Adult; Aged; Analysis of Variance; Antihypertensive Agents; Bimatoprost; Electroretinography; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Retinal Ganglion Cells; Timolol; Vision, Ocular; Visual Field Tests | 2017 |
Clinical case of influenza A with outer retinal maculopathy.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Eye Infections, Viral; Fluorescein Angiography; Glucocorticoids; Humans; Influenza A virus; Influenza, Human; Intraocular Pressure; Male; Middle Aged; Nasopharynx; Retinal Diseases; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence; Visual Acuity | 2017 |
Recurrent serous macular detachment after topical ocular hypotensive medication.
Topics: Administration, Topical; Antihypertensive Agents; Clonidine; Drug Combinations; Drug Therapy, Combination; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Recurrence; Retinal Detachment; Serum; Sulfonamides; Thiophenes; Timolol; Tomography, Optical Coherence; Visual Acuity | 2008 |
Side effects of commonly used glaucoma medications: comparison of tolerability, chance of discontinuation, and patient satisfaction.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ophthalmic Solutions; Patient Compliance; Patient Satisfaction; Prostaglandins F, Synthetic; Sulfonamides; Surveys and Questionnaires; Thiophenes; Timolol | 2008 |
[Late postoperative choroidal detachment].
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Choroid Diseases; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypotension; Ophthalmic Solutions; Phacoemulsification; Timolol; Trabeculectomy; Treatment Outcome; Visual Acuity; Visual Fields | 2008 |
[Triamcinolone in anterior chamber].
Topics: Adult; Anterior Chamber; Chalazion; Female; Humans; Intraocular Pressure; Timolol; Triamcinolone Acetonide | 2008 |
Ocular pharmacokinetic/pharmacodynamic modeling for multiple anti-glaucoma drugs.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Algorithms; Animals; Aqueous Humor; Drug Combinations; Glaucoma; Intraocular Pressure; Male; Models, Statistical; Ocular Hypertension; Ophthalmic Solutions; Quinazolines; Rabbits; Telemetry; Timolol | 2008 |
Performing meta-analysis with incomplete statistical information in clinical trials.
Topics: Antihypertensive Agents; Cholesterol, LDL; Clinical Trials as Topic; Data Interpretation, Statistical; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Humans; Hypoglycemic Agents; Intraocular Pressure; Latanoprost; Meta-Analysis as Topic; Metformin; Ocular Hypertension; Prostaglandins F, Synthetic; Sampling Studies; Sulfonylurea Compounds; Thiazolidinediones; Time Factors; Timolol | 2008 |
Changes in intraocular pressure following a switch from latanoprost monotherapy to latanoprost/timolol fixed combination therapy in patients with primary open-angle glaucoma or ocular hypertension: results from a clinical practice database.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Databases, Factual; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Retrospective Studies; Timolol | 2008 |
Comparison of topical and intravenous administration of WIN 55-212-2 in normotensive rabbits.
Topics: Administration, Topical; Animals; Benzoxazines; Blood Pressure; Cannabinoids; Dose-Response Relationship, Drug; Female; Heart Rate; Injections, Intravenous; Intraocular Pressure; Morpholines; Naphthalenes; Rabbits; Timolol; Tonometry, Ocular | 2008 |
Anterior uveitis associated with fixed-combination latanoprost and timolol.
Topics: Antihypertensive Agents; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Timolol; Uveitis, Anterior | 2008 |
Intraocular pressure lowering, change of antiapoptotic molecule expression, and neuroretinal changes by dorzolamide 2%/timolol 0.5% combination in a chronic ocular hypertension rat model.
Topics: Animals; bcl-X Protein; Cell Survival; Disease Models, Animal; Drug Combinations; Glial Fibrillary Acidic Protein; Intraocular Pressure; Male; Ocular Hypertension; Proto-Oncogene Proteins c-bcl-2; Rats; Rats, Sprague-Dawley; Retinal Ganglion Cells; RNA, Messenger; Sulfonamides; Thiophenes; Timolol | 2008 |
Bilateral acute onset myopia and angle closure glaucoma after oral topiramate: a case report.
Topics: Acetazolamide; Acute Disease; Adult; Anticonvulsants; Antihypertensive Agents; Cryoprotective Agents; Female; Fructose; Glaucoma, Angle-Closure; Glycerol; Humans; Intraocular Pressure; Myopia; Risk Factors; Timolol; Topiramate | 2008 |
An in vivo confocal microscopy analysis of effects of topical antiglaucoma therapy with preservative on corneal innervation and morphology.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Benzalkonium Compounds; Cell Count; Cornea; Drug Combinations; Epithelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Microscopy, Confocal; Middle Aged; Ocular Hypertension; Ophthalmic Nerve; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Retrospective Studies; Timolol | 2009 |
Treatment of patients with primary open-angle glaucoma with a fixed combination of brimonidine 0.2%/timolol 0.5%: multicenter, open-label, observational study in Germany.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Brimonidine Tartrate; Drug Therapy, Combination; Female; Germany; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Quinoxalines; Timolol; Visual Fields; Young Adult | 2009 |
Cytochrome oxidase 2D6 gene polymorphism in primary open-angle glaucoma with various effects to ophthalmic timolol.
Topics: Administration, Topical; Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Bradycardia; Cytochrome P-450 CYP2D6; Female; Genotype; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Polymorphism, Single Nucleotide; Timolol; Young Adult | 2009 |
Efficacy, tolerability and safety of the fixed combination of bimatoprost 0.03% and timolol 0.5% in a broad patient population: multicenter, open-label observational study.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Optic Disk; Timolol; Visual Fields | 2009 |
A medical device/drug delivery system for treatment of glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Brimonidine Tartrate; Chromatography, High Pressure Liquid; Contact Lenses; Drug Delivery Systems; Female; Glaucoma; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Intraocular Pressure; Male; Middle Aged; Quinoxalines; Timolol | 2009 |
Enalaprilat and enalapril maleate eyedrops lower intraocular pressure in rabbits.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Enalapril; Enalaprilat; Female; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Time Factors; Timolol; Tonometry, Ocular | 2010 |
Relationship between visual field severity and response to fixed combination dorzolamide/timolol or timolol alone.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Double-Blind Method; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Linear Models; Male; Middle Aged; Ocular Hypertension; Randomized Controlled Trials as Topic; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2009 |
Decreased intraocular pressure in mice following either pharmacological or genetic inhibition of ROCK.
Topics: Acetazolamide; Administration, Topical; Adrenergic beta-Antagonists; Amides; Animals; Antihypertensive Agents; Dose-Response Relationship, Drug; Intraocular Pressure; Latanoprost; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Muscarinic Agonists; Pilocarpine; Prostaglandins F, Synthetic; Pyridines; rho-Associated Kinases; Timolol | 2009 |
L-Carnosine: multifunctional dipeptide buffer for sustained-duration topical ophthalmic formulations.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Buffers; Carnosine; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Delayed-Action Preparations; Dipeptides; Dogs; Drug Carriers; Drug Compounding; Drug Stability; Excipients; Female; Gels; Hydrogen-Ion Concentration; Intraocular Pressure; Male; Ophthalmic Solutions; Polysaccharides, Bacterial; Rabbits; Rheology; Timolol | 2009 |
Brinzolamide/timolol: in open-angle glaucoma and ocular hypertension.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Clinical Trials as Topic; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Sulfonamides; Thiazines; Timolol | 2009 |
Effects of timolol and latanoprost on respiratory and cardiovascular status in elderly patients with glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Blood Pressure; Cardiovascular System; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prospective Studies; Prostaglandins F, Synthetic; Respiration; Spirometry; Timolol; Treatment Outcome | 2009 |
Intraocular pressure-lowering activity of topical application of Aegle marmelos fruit extract in experimental animal models.
Topics: Administration, Topical; Aegle; Animals; Antihypertensive Agents; Disease Models, Animal; Fruit; Glaucoma; Intraocular Pressure; Ocular Hypertension; Phytotherapy; Plant Extracts; Rabbits; Timolol; Tonometry, Ocular | 2009 |
Corneal thickness and glaucoma medications.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Cornea; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Relative efficacy of prostaglandins.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Double-Blind Method; Drug Administration Schedule; Drug Combinations; Drug Therapy, Combination; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Single-Blind Method; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome | 2009 |
Smoothing the intraocular pressure roller coaster: a new goal?
Topics: Antihypertensive Agents; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Patient Compliance; Prostaglandins F, Synthetic; Risk Factors; Timolol; Tonometry, Ocular; Treatment Outcome | 2009 |
Aerobic exercise and intraocular pressure in normotensive and glaucoma patients.
Topics: Adolescent; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Exercise; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2009 |
Experimental model of ocular hypertension in the rat: study of the optic nerve capillaries and action of hypotensive drugs.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Capillaries; Disease Models, Animal; Glucose Transporter Type 1; Immunoenzyme Techniques; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Optic Disk; Optic Nerve; Prostaglandins F, Synthetic; Rats; Rats, Wistar; Timolol | 2010 |
Reaction of Müller cells in an experimental rat model of increased intraocular pressure following timolol, latanoprost and brimonidine.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Disease Models, Animal; Glaucoma; Glial Fibrillary Acidic Protein; Gliosis; Intraocular Pressure; Latanoprost; Male; Neuroglia; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Retina; Timolol; Tonometry, Ocular | 2010 |
Improved ocular absorption kinetics of timolol maleate loaded into a bioadhesive niosomal delivery system.
Topics: Absorption; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Cornea; Drug Delivery Systems; Intraocular Pressure; Liposomes; Male; Microdialysis; Permeability; Rabbits; Timolol | 2010 |
Efficacy of tetrandrine on lowering intraocular pressure in animal model with ocular hypertension.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Benzylisoquinolines; Disease Models, Animal; Drugs, Chinese Herbal; Intraocular Pressure; Male; Ocular Hypertension; Rats; Rats, Sprague-Dawley; Timolol; Tonometry, Ocular; Treatment Outcome | 2011 |
Impact of once daily versus twice daily application of adjunctive timolol on the intraocular pressure-lowering effect of latanoprost.
Topics: Antihypertensive Agents; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Optic Nerve Diseases; Prostaglandins F, Synthetic; Timolol | 2010 |
Efficacy of medical therapy in the initial management of acute primary angle closure in Asians.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Asian People; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Singapore; Timolol; Visual Acuity | 2010 |
Latanoprost versus timolol as first choice therapy in patients with ocular hypertension. A cost-effectiveness analysis.
Topics: Adult; Aged; Aged, 80 and over; Aging; Antihypertensive Agents; Blindness; Cost-Benefit Analysis; Decision Trees; Drug Costs; Female; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Theoretical; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Tonometry, Ocular | 2012 |
Effects of topical administration of latanoprost, timolol, or a combination of latanoprost and timolol on intraocular pressure, pupil size, and heart rate in clinically normal dogs.
Topics: Administration, Topical; Animals; Antihypertensive Agents; Dog Diseases; Dogs; Drug Therapy, Combination; Glaucoma; Heart Rate; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Reference Values; Species Specificity; Tears; Timolol | 2010 |
Long-term effect of latanoprost/timolol fixed combination in patients with glaucoma or ocular hypertension: a prospective, observational, noninterventional study.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Child; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Time Factors; Timolol; Treatment Outcome; Visual Fields; Young Adult | 2010 |
Effectiveness of dorzolamide–timolol (COSOPT) in patients who were treatment naive for open-angle glaucoma or ocular hypertension: the COSOPT first-line study.
Topics: Aged; Drug Combinations; Eye; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Multicenter Studies as Topic; Ocular Hypertension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
Association of CYP2D6 single-nucleotide polymorphism with response to ophthalmic timolol in primary open-angle Glaucoma--a pilot study.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Bradycardia; Cytochrome P-450 CYP2D6; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pilot Projects; Polymorphism, Single Nucleotide; Timolol | 2010 |
Comparison of evening and morning dosing of travoprost 0.004%/timolol 0.5% fixed combination in 6 month period.
Topics: Cloprostenol; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Prospective Studies; Timolol; Travoprost | 2010 |
Efficacy and tolerability of preservative-free eye drops containing a fixed combination of dorzolamide and timolol in glaucoma patients.
Topics: Administration, Topical; Aged; Antihypertensive Agents; Benzalkonium Compounds; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Hyperemia; Intraocular Pressure; Male; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2010 |
Hyperemia reduction after administration of a fixed combination of bimatoprost and timolol maleate to patients on prostaglandin or prostamide monotherapy.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Follow-Up Studies; Glaucoma; Humans; Hyperemia; Intraocular Pressure; Latanoprost; Longitudinal Studies; Prostaglandins F, Synthetic; Time Factors; Timolol; Travoprost | 2010 |
Effects of brimonidine 0.2%-timolol 0.5% fixed-combination therapy for glaucoma.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Low Tension Glaucoma; Male; Middle Aged; Prospective Studies; Pupil; Quinoxalines; Timolol; Tonometry, Ocular; Treatment Outcome | 2010 |
The clinical impact of 2 different strategies for initiating therapy in patients with ocular hypertension.
Topics: Adult; Antihypertensive Agents; Blindness; Brimonidine Tartrate; Decision Trees; Disease Progression; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Markov Chains; Middle Aged; Models, Biological; Monte Carlo Method; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Risk Assessment; Sulfonamides; Thiophenes; Timolol | 2011 |
Bimatoprost and bimatoprost/timolol fixed combination in patients with open-angle glaucoma and ocular hypertension.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Circadian Rhythm; Cloprostenol; Drug Combinations; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Single-Blind Method; Timolol; Treatment Outcome | 2011 |
Comparison of the in vitro tolerance and in vivo efficacy of traditional timolol maleate eye drops versus new formulations with bioadhesive polymers.
Topics: Animals; Carboxymethylcellulose Sodium; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Conjunctiva; Epithelium, Corneal; Humans; Hyaluronic Acid; Hydrogen-Ion Concentration; Hypromellose Derivatives; Intraocular Pressure; Male; Methylcellulose; Ophthalmic Solutions; Osmolar Concentration; Pharmaceutical Preparations; Preservatives, Pharmaceutical; Rabbits; Rheology; Timolol; Tonometry, Ocular | 2011 |
[Comparison of primary medicament therapy effects and primary argon laser trabeculoplasty on regulation of intraocular pressure and stability of perimetry findings in open angle glaucoma].
Topics: Aged; Antihypertensive Agents; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Lasers, Gas; Latanoprost; Male; Middle Aged; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Visual Field Tests | 2011 |
Familial juvenile glaucoma with underlying homozygous p.G61E CYP1B1 mutations.
Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Carrier State; Child; Consanguinity; Cytochrome P-450 CYP1B1; Cytoskeletal Proteins; Eye Proteins; Female; Glaucoma, Open-Angle; Glycoproteins; Gonioscopy; Homozygote; Humans; Intraocular Pressure; Male; Mutation; Pedigree; Siblings; Timolol; Visual Acuity | 2011 |
Characterization of intraocular pressure responses of the Tibetan monkey (Macaca thibetana).
Topics: Animals; Antihypertensive Agents; Circadian Rhythm; Cloprostenol; Eye; Glaucoma; Intraocular Pressure; Macaca; Male; Models, Animal; Naphazoline; Pyrrolidines; Timolol; Tonometry, Ocular; Travoprost | 2011 |
Comparison of selective laser trabeculoplasty success in patients treated with either prostaglandin or timolol/dorzolamide fixed combination.
Topics: Aged; Antihypertensive Agents; Drug Combinations; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Prostaglandins, Synthetic; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Trabeculectomy; Treatment Outcome | 2011 |
Asymmetry of 24-hour intraocular pressure reduction by topical ocular hypotensive medications in fellow eyes.
Topics: Administration, Topical; Adult; Aged; Antihypertensive Agents; Brimonidine Tartrate; Circadian Rhythm; Cloprostenol; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Posture; Prostaglandins F, Synthetic; Quinoxalines; Retrospective Studies; Sulfonamides; Thiazines; Timolol; Tonometry, Ocular; Travoprost | 2011 |
Effects of brimonidine timolol fixed combination therapy on anterior ocular segment configuration.
Topics: Adult; Anterior Eye Segment; Antihypertensive Agents; Brimonidine Tartrate; Drug Combinations; Female; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Pilocarpine; Pupil; Quinoxalines; Timolol; Tonometry, Ocular | 2011 |
Long-term outcomes of prostaglandin analog versus timolol maleate in ocular hypertensive or primary open-angle glaucoma patients in Europe.
Topics: Aged; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Disease Progression; Drug Costs; Europe; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prostaglandins F, Synthetic; Retrospective Studies; Time Factors; Timolol; Travoprost; Treatment Outcome | 2011 |
Safety and efficacy of monotherapy change to fixed combination (travoprost 0.004%/timolol 0.5%) in 6 months follow up period.
Topics: Antihypertensive Agents; Cloprostenol; Drug Combinations; Drug Substitution; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Timolol; Travoprost | 2010 |
The extended ocular hypotensive effect of positive liposomal cholesterol bound timolol maleate in glaucomatous rabbits.
Topics: 1,2-Dipalmitoylphosphatidylcholine; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Calorimetry, Differential Scanning; Cholesterol; Delayed-Action Preparations; Glaucoma; Intraocular Pressure; Liposomes; Male; Phenol; Rabbits; Sclerosing Solutions; Spectrophotometry, Ultraviolet; Timolol | 2011 |
Phacomorphic intermittent angle closure in a patient with retinopathy of prematurity and lenticular high myopia.
Topics: Adult; Anterior Chamber; Antihypertensive Agents; Female; Glaucoma, Angle-Closure; Gonioscopy; Humans; Infant, Newborn; Intraocular Pressure; Iridectomy; Iris; Laser Coagulation; Lasers, Solid-State; Myopia, Degenerative; Pilocarpine; Retinopathy of Prematurity; Timolol; Visual Acuity | 2012 |
The long-term outcomes of four alternative treatment strategies for primary open-angle glaucoma.
Topics: Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Cost-Benefit Analysis; Decision Support Techniques; Disease Progression; Drug Costs; Economics, Pharmaceutical; Follow-Up Studies; Glaucoma, Open-Angle; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quality-Adjusted Life Years; Quinoxalines; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2012 |
New mucoadhesive chitosan film for ophthalmic drug delivery of timolol maleate: in vivo evaluation.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Calorimetry, Differential Scanning; Chitosan; Drug Delivery Systems; Eye; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Solubility; Spectrophotometry, Ultraviolet; Spectroscopy, Fourier Transform Infrared; Timolol; Tissue Adhesives; Water | 2012 |
Generic versus brand-name North American topical glaucoma drops.
Topics: Administration, Topical; Antihypertensive Agents; Canada; Drug Packaging; Drugs, Generic; Glaucoma, Open-Angle; Intraocular Pressure; Ophthalmic Solutions; Prescription Drugs; Surface Tension; Therapeutic Equivalency; Timolol; United States; Viscosity | 2012 |
Drug delivery by contact lens in spontaneously glaucomatous dogs.
Topics: Animals; Antihypertensive Agents; Biological Availability; Contact Lenses, Hydrophilic; Disease Models, Animal; Dogs; Drug Delivery Systems; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Timolol; Vitamin E | 2012 |
The effects of a fixed combination of 0.5% timolol and 1% dorzolamide on optic nerve head blood circulation.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Blood Pressure; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Synergism; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Optic Disk; Perfusion; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol; Young Adult | 2012 |
Efficacy and safety of switching to travoprost/timolol fixed-combination therapy from latanoprost monotherapy.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Blood Pressure; Cloprostenol; Drug Combinations; Drug Substitution; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Ocular Hypertension; Prospective Studies; Prostaglandins F, Synthetic; Surveys and Questionnaires; Timolol; Tonometry, Ocular; Travoprost; Treatment Outcome; Young Adult | 2012 |
Microbead-induced ocular hypertensive mouse model for screening and testing of aqueous production suppressants for glaucoma.
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Disease Models, Animal; Drug Evaluation, Preclinical; Feasibility Studies; Intraocular Pressure; Latanoprost; Mice; Mice, Inbred C57BL; Microspheres; Muscarinic Agonists; Ocular Hypertension; Optic Nerve; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Retinal Ganglion Cells; Sulfonamides; Thiazines; Timolol; Tomography, Optical Coherence | 2012 |
Resolution of bilateral ptosis after reduction of unilaterally elevated intraocular pressure in a child with Axenfeld-Reiger spectrum disorder.
Topics: Anterior Eye Segment; Antihypertensive Agents; Blepharoptosis; Drug Combinations; Eye Abnormalities; Eye Diseases, Hereditary; Glaucoma; Humans; Infant; Intraocular Pressure; Male; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2012 |
Extended drug delivery by contact lenses for glaucoma therapy.
Topics: Animals; Antihypertensive Agents; Contact Lenses, Extended-Wear; Dogs; Drug Delivery Systems; Eye; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Timolol; Vitamin E | 2012 |
A neurobehavioral analysis of the prevention of visual impairment in the DBA/2J mouse model of glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aging; Animals; Behavior, Animal; Cell Count; Disease Models, Animal; Female; Glaucoma, Open-Angle; Intraocular Pressure; Male; Mice; Mice, Inbred DBA; Ophthalmic Solutions; Retinal Ganglion Cells; Superior Colliculi; Timolol; Treatment Outcome; Vision Disorders; Visual Perception; Wheat Germ Agglutinin-Horseradish Peroxidase Conjugate | 2012 |
[The rabbit's IOP values after instillation of the L-arginine HCL with selected antiglaucomatic drugs mixtures prepared in vitro. (comparative study of results of the experimental works)].
Topics: Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Thiophenes; Timolol | 2012 |
[Use of glaucoma medications during pregnancy and breastfeeding].
Topics: Abnormalities, Drug-Induced; Administration, Ophthalmic; Administration, Oral; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Carbonic Anhydrase Inhibitors; Contraindications; Female; Fetus; Gels; Glaucoma; Humans; Hypotension; Intraocular Pressure; Lactation; Obstetric Labor, Premature; Ophthalmic Solutions; Pregnancy; Pregnancy Complications; Prostaglandins; Quinoxalines; Timolol | 2012 |
Effect of topical Beta blocker (Timolol maleate 0.5%) in primary open angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Timolol; Visual Acuity | 2012 |
Congenital glaucoma with acquired peripheral circumferential iris degeneration.
Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP1B1; Drug Therapy, Combination; Eye Abnormalities; Female; Forkhead Transcription Factors; Humans; Hydrophthalmos; Infant; Intraocular Pressure; Iris; Point Mutation; Sequence Deletion; Sulfonamides; Thiophenes; Timolol | 2013 |
Comparison of tropical travoprost eye drops given once daily and timolol 0.5% given twice daily in patients with open-angle glaucoma or ocular hypertension. J. Glaucoma 2001;10:414-22.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost | 2002 |
Identification and characterization of the ocular hypotensive efficacy of travoprost, a potent and selective FP prostaglandin receptor agonist, and AL-6598, a DP prostaglandin receptor agonist.
Topics: Animals; Antihypertensive Agents; Aqueous Humor; Cats; Cloprostenol; Dinoprost; Dose-Response Relationship, Drug; Female; Glaucoma, Open-Angle; Guinea Pigs; Humans; Intraocular Pressure; Macaca fascicularis; Male; Ocular Hypertension; Rabbits; Randomized Controlled Trials as Topic; Receptors, Immunologic; Receptors, Prostaglandin; Safety; Structure-Activity Relationship; Timolol; Travoprost | 2002 |
The pulsatile ocular blood flow behaviour in open angle glaucoma patients after replacing timolol therapy with timolol and dorzolamide fixed combination: preliminary study.
Topics: Adrenergic beta-Antagonists; Aged; Blood Flow Velocity; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pulsatile Flow; Sulfonamides; Thiophenes; Timolol | 2002 |
[Chronic glaucoma].
Topics: Adrenergic beta-Antagonists; Diagnosis, Differential; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Ophthalmic Solutions; Optic Disk; Timolol; Visual Field Tests | 2002 |
Evaluation of the intraocular pressure-reducing effect of latanoprost as monotherapy in open-angle glaucoma.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Pilocarpine; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2002 |
Nurse prescribing in glaucoma.
Topics: Aged; Aged, 80 and over; Antihypertensive Agents; Clinical Competence; Clinical Protocols; Drug Prescriptions; England; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Nurse Practitioners; Nursing Audit; Nursing Staff, Hospital; Outpatient Clinics, Hospital; Prostaglandins F, Synthetic; Timolol | 2003 |
[Glaucoma: an ocular blood flow disorder?].
Topics: Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Eye; Female; Glaucoma; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Rheology; Risk Factors; Sulfonamides; Thiophenes; Time Factors; Timolol | 2003 |
Experience with COSOPT, the fixed combination of timolol and dorzolamide, gained in Swiss ophthalmologists' offices.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Carbonic Anhydrase Inhibitors; Child; Drug Combinations; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Neuroprotective Agents; Physicians' Offices; Practice Patterns, Physicians'; Prostaglandins F, Synthetic; Sulfonamides; Switzerland; Thiophenes; Timolol; Treatment Outcome | 2003 |
Comparison of the efficacy of the fixed-combination timolol/dorzolamide versus concomitant administration of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Aged; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2003 |
Experience with Cosopt, the fixed combination of timolol and dorzolamide, after switch from free combination of timolol and dorzolamide, in Swiss ophthalmologists' offices.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cluster Analysis; Drug Combinations; Female; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Ophthalmology; Sulfonamides; Switzerland; Thiophenes; Timolol | 2003 |
Hemorrhagic Descemet's membrane detachment after viscocanalostomy.
Topics: Corneal Diseases; Corneal Topography; Descemet Membrane; Exfoliation Syndrome; Hemorrhage; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmologic Surgical Procedures; Remission, Spontaneous; Timolol; Visual Acuity | 2003 |
Real-time direct measurement of nitric oxide in bovine perfused eye trabecular meshwork using a clark-type electrode.
Topics: Animals; Aqueous Humor; Cattle; Dose-Response Relationship, Drug; Electrochemistry; Epinephrine; Intraocular Pressure; Nitric Oxide; Nitric Oxide Synthase; Nitrites; omega-N-Methylarginine; Perfusion; Timolol; Trabecular Meshwork | 2003 |
[A combination of timoptol and L-arginine HCl: a regulator of intraocular pressure in rabbits].
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Drug Combinations; Female; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Timolol | 2003 |
ESCRS Binkhorst lecture 2002: Pseudophakic preservative maculopathy.
Topics: Aqueous Humor; Cataract Extraction; Humans; Incidence; Inflammation; Intraocular Pressure; Latanoprost; Macular Edema; Ophthalmic Solutions; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Pseudophakia; Timolol | 2003 |
[Effects of ocular hypotensive agents on the circadian rhythm in intraocular pressure in rabbits as measured by telemetry].
Topics: Animals; Circadian Rhythm; Intraocular Pressure; Male; Quinazolines; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol | 2003 |
In vitro effects of preserved or preservative-free antiglaucoma medications on human complement system.
Topics: Adrenergic beta-Antagonists; Benzalkonium Compounds; Betaxolol; Carteolol; Complement System Proteins; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Preservatives, Pharmaceutical; Prostaglandins F, Synthetic; Timolol | 2003 |
Timolol + latanoprost: new preparation. Last-resort eye drops.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2003 |
Persistency with latanoprost or timolol in primary open-angle glaucoma suspects.
Topics: Adult; Aged; Aged, 80 and over; Antihypertensive Agents; Cohort Studies; Drug Prescriptions; Drug Utilization; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Managed Care Programs; Middle Aged; Ophthalmic Solutions; Patient Compliance; Prostaglandins F, Synthetic; Retrospective Studies; Timolol | 2004 |
Optic nerve oxygen tension: the effects of timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Carbon Dioxide; Carbonic Anhydrase Inhibitors; Drug Interactions; Heart Rate; Intraocular Pressure; Optic Disk; Oxygen; Partial Pressure; Sulfonamides; Swine; Thiophenes; Timolol | 2004 |
Ocular blood flow and systemic blood pressure in patients with primary open-angle glaucoma and ocular hypertension.
Topics: Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Choroid; Clinical Trials as Topic; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Male; Middle Aged; Ocular Hypertension; Optic Disk; Pulsatile Flow; Regional Blood Flow; Retrospective Studies; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2004 |
Brimonidine and latanoprost as adjunctive therapy.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Timolol | 2004 |
Is addition of a third or fourth antiglaucoma medication effective?
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Prostaglandins; Retrospective Studies; Safety; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2004 |
Binding affinities of ocular hypotensive beta-blockers levobetaxolol, levobunolol, and timolol at endogenous guinea pig beta-adrenoceptors.
Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Binding, Competitive; Guinea Pigs; Heart; In Vitro Techniques; Intraocular Pressure; Levobunolol; Lung; Myocardium; Receptors, Adrenergic, beta; Timolol | 2004 |
[Comparison of the effectiveness of a mixture of 10% L-arginine and HCl combined with 0.5% Timoptol and with 2% Trusopt: and the individual components on intraocular pressure in an experiment on rabbits].
Topics: Animals; Antihypertensive Agents; Arginine; Carbonic Anhydrase Inhibitors; Drug Combinations; Intraocular Pressure; Male; Rabbits; Sulfonamides; Thiophenes; Timolol | 2004 |
Persistency and treatment failure in newly diagnosed open angle glaucoma patients in the United Kingdom.
Topics: Adrenergic beta-Antagonists; Aged; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Miotics; Prostaglandins F, Synthetic; Risk Factors; Sympathomimetics; Timolol; Treatment Failure | 2004 |
[Measurement of corneal thickness in cases where tonometry is contraindicated].
Topics: Antihypertensive Agents; Computer Graphics; Corneal Topography; Diagnosis, Differential; Drug Combinations; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Manometry; Middle Aged; Optic Disk; Prostaglandins F, Synthetic; Signal Processing, Computer-Assisted; Sulfonamides; Thiophenes; Timolol; Visual Fields | 2004 |
Tales of two drugs.
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Drug Design; Glaucoma; History, 20th Century; History, 21st Century; Humans; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pharmaceutical Preparations; Pharmacology; Prostaglandins F, Synthetic; Timolol | 2005 |
Bimatoprost versus timolol and dorzolamide.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Lipids; Ocular Hypertension; Ophthalmic Solutions; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol | 2005 |
The effect of combination pharmacotherapy on the prescription trends of glaucoma medications.
Topics: Antihypertensive Agents; Drug Combinations; Drug Prescriptions; Drug Utilization; Glaucoma, Open-Angle; Health Maintenance Organizations; Health Services Research; Health Surveys; Humans; Intraocular Pressure; Israel; Ocular Hypertension; Practice Patterns, Physicians'; Sulfonamides; Thiophenes; Timolol | 2005 |
Bilateral retinal venous occlusion in pigmentary glaucoma.
Topics: Adult; Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Exfoliation Syndrome; Functional Laterality; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Quinoxalines; Retinal Vein Occlusion; Timolol; Trabecular Meshwork; Vision Disorders; Visual Field Tests; Visual Fields | 2005 |
Topically administered timolol and dorzolamide reduce intraocular pressure and protect retinal ganglion cells in a rat experimental glaucoma model.
Topics: Animals; Antihypertensive Agents; Cell Count; Cell Survival; Cytoprotection; Disease Models, Animal; Glaucoma; Intraocular Pressure; Male; Ophthalmic Solutions; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Timolol | 2005 |
[IOP in rabbits after instillation of a mixture of the antiglaucomatic Cosopt and the aminoacid L-argininin HCL into the conjunctival sac].
Topics: Animals; Arginine; Drug Combinations; Female; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Thiophenes; Timolol | 2005 |
Fluctuating intraocular pressure.
Topics: Antihypertensive Agents; Circadian Rhythm; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Optic Disk; Optic Nerve Diseases; Timolol; Vision Disorders; Visual Fields | 2005 |
[The rabbit IOP and pupil values after application of aminoacid L-lysine and antiglaucomatic Timoptol mixture].
Topics: Animals; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Lysine; Pupil; Rabbits; Timolol | 2005 |
How to control measurement variation in estimating the mean intraocular pressure reducing effect at a specific point in time.
Topics: Antihypertensive Agents; Functional Laterality; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Models, Statistical; Multicenter Studies as Topic; Ocular Hypertension; Prostaglandins F, Synthetic; Randomized Controlled Trials as Topic; Research Design; Sample Size; Time Factors; Timolol; Tonometry, Ocular | 2005 |
Modern alchemy: fixed combinations of glaucoma drugs.
Topics: Antihypertensive Agents; Cloprostenol; Drug Combinations; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Safety; Timolol; Travoprost; Treatment Outcome | 2005 |
Reversal of laser in situ keratomileusis-induced ectasia with intraocular pressure reduction.
Topics: Adult; Antihypertensive Agents; Corneal Diseases; Corneal Topography; Dilatation, Pathologic; Female; Humans; Intraocular Pressure; Keratomileusis, Laser In Situ; Myopia; Timolol; Visual Acuity | 2005 |
Effects of a non-selective beta-blocker on adult rat anterograde axonal transport and retinal ganglion layer after increased intraocular pressure.
Topics: Adrenergic beta-Antagonists; Animals; Axonal Transport; Disease Models, Animal; Glaucoma; Intraocular Pressure; Male; Ocular Hypertension; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; Timolol | 2005 |
Polymorphism of the beta-2 adrenoceptor and IOP lowering potency of topical timolol in healthy subjects.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Blood Pressure; DNA Mutational Analysis; Genotype; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Polymorphism, Genetic; Receptors, Adrenergic, beta-2; Reverse Transcriptase Polymerase Chain Reaction; Timolol; Tonometry, Ocular | 2005 |
The efficacy of timolol in gel-forming solution after morning or evening dosing in Asian glaucomatous patients.
Topics: Adult; Aged; Asian People; Female; Gels; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Retrospective Studies; Time Factors; Timolol | 2005 |
Continuous monitoring of circadian variations in intraocular pressure by telemetry system throughout a 12-week treatment with timolol maleate in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Circadian Rhythm; Instillation, Drug; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Telemetry; Time Factors; Timolol | 2005 |
Physicochemical properties and in vivo assessment of timolol-loaded poly(D,L-lactide-co-glycolide) films for long-term intraocular pressure lowering effects.
Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Chromatography, High Pressure Liquid; Disease Models, Animal; Drug Delivery Systems; Intraocular Pressure; Male; Ocular Hypertension; Polyglactin 910; Rabbits; Solubility; Surface Properties; Tensile Strength; Time Factors; Timolol; Treatment Outcome | 2005 |
Dorzolamide and timolol saves retinal ganglion cells in glaucomatous adult rats.
Topics: Animals; Antihypertensive Agents; Cell Count; Disease Models, Animal; Drug Combinations; Female; Glaucoma; Intraocular Pressure; Pilot Projects; Rats; Rats, Wistar; Retinal Ganglion Cells; Sulfonamides; Thiophenes; Time Factors; Timolol | 2005 |
The state of being noninferior.
Topics: Antihypertensive Agents; Choroidal Neovascularization; Clinical Trials as Topic; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Macular Degeneration; Photochemotherapy; Practice Guidelines as Topic; Pregnadienediols; Prostaglandins F, Synthetic; Research Design; Timolol | 2006 |
[Reduction of the physiologic IOP value after instilation of the mixture of the 2 amino acid's (L-lysine and L-arginine) in timoptol--experiment on rabbit's].
Topics: Adrenergic beta-Antagonists; Animals; Arginine; Drug Combinations; Drug Synergism; Female; Intraocular Pressure; Lysine; Ophthalmic Solutions; Rabbits; Timolol | 2006 |
Does timolol LA enhance the disrupting effect of travoprost on the blood-aqueous barrier?
Topics: Adult; Antihypertensive Agents; Blood-Aqueous Barrier; Cloprostenol; Drug Synergism; Drug Therapy, Combination; Gonioscopy; Humans; Intraocular Pressure; Male; Ocular Hypertension; Timolol; Travoprost; Uveitis, Anterior | 2006 |
The cost-effectiveness of bimatoprost, latanoprost and timolol in treatment of primary open angle glaucoma in five European countries.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Controlled Clinical Trials as Topic; Cost-Benefit Analysis; Decision Trees; Drug Costs; Economics, Pharmaceutical; Europe; Glaucoma, Open-Angle; Health Care Costs; Humans; Intraocular Pressure; Latanoprost; Lipids; Models, Econometric; Prostaglandins F, Synthetic; Timolol | 2006 |
[Evolution of secondary pseudoexfoliative glaucoma after cataract surgery in patients with cataract-glaucoma combination].
Topics: Adrenergic beta-Antagonists; Cataract; Cataract Extraction; Evaluation Studies as Topic; Exfoliation Syndrome; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lens Implantation, Intraocular; Ophthalmic Solutions; Phacoemulsification; Prospective Studies; Timolol; Visual Acuity; Visual Fields | 2006 |
[The effect of glycine with timoptol on the rabbit IOP physiological values].
Topics: Adrenergic beta-Antagonists; Animals; Drug Combinations; Glycine; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Timolol | 2006 |
In vivo confocal microscopic findings of interlamellar stromal keratopathy induced by elevated intraocular pressure.
Topics: Acetazolamide; Adult; Antihypertensive Agents; Corneal Diseases; Corneal Stroma; Drug Therapy, Combination; Glucocorticoids; Humans; Intraocular Pressure; Keratomileusis, Laser In Situ; Male; Microscopy, Confocal; Ocular Hypertension; Postoperative Complications; Prednisolone; Timolol; Visual Acuity | 2006 |
Measurement of inflammatory cytokines by multicytokine assay in tears of patients with glaucoma topically treated with chronic drugs.
Topics: Administration, Topical; Aged; Amides; Antihypertensive Agents; Bimatoprost; Brimonidine Tartrate; Carteolol; Case-Control Studies; Chemokines; Cloprostenol; Cytokines; Dose-Response Relationship, Immunologic; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Lipids; Male; Prospective Studies; Prostaglandins F, Synthetic; Quinoxalines; Sulfonamides; Tears; Thiophenes; Timolol | 2007 |
What's in a name? New glaucoma drugs.
Topics: Adrenergic beta-Antagonists; Aged; Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Timolol | 2006 |
Effect of 2% dorzolamide on retinal blood flow: a study on juvenile primary open-angle glaucoma patients already receiving 0.5% timolol.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Carbonic Anhydrase Inhibitors; Drug Interactions; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Regional Blood Flow; Sulfonamides; Thiophenes; Timolol | 2007 |
Brimonidine/Timolol: a viewpoint by Richard Fiscella.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Quinoxalines; Randomized Controlled Trials as Topic; Timolol; Treatment Outcome | 2006 |
Brimonidine/Timolol: a viewpoint by Francisco J. Goñi.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Randomized Controlled Trials as Topic; Sulfonamides; Thiophenes; Timolol; Treatment Outcome | 2006 |
Nitric oxide synthase in retina and optic nerve head of rat with increased intraocular pressure and effect of timolol.
Topics: Animals; Antihypertensive Agents; Glial Fibrillary Acidic Protein; Immunohistochemistry; Intraocular Pressure; Male; Nitric Oxide Synthase; Optic Nerve; Rats; Rats, Wistar; Retina; Timolol | 2006 |
The state of being noninferior.
Topics: Drug Administration Schedule; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 2006 |
Intraocular pressure lowering effect of dorzolamide/timolol fixed combination in patients with glaucoma who were unresponsive to prostaglandin analogs/prostamides.
Topics: Cohort Studies; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Combinations; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Probability; Prostaglandins, Synthetic; Retrospective Studies; Severity of Illness Index; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular; Treatment Failure; Treatment Outcome | 2007 |
Resistance to blood flow in the rabbit ophthalmic artery after topical treatment with timolol.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Blood Pressure; Dose-Response Relationship, Drug; Eye; Heart Rate; Intraocular Pressure; Ophthalmic Artery; Rabbits; Regional Blood Flow; Timolol; Ultrasonography, Doppler, Color | 2007 |
Hypotony and choroidal detachment as a complication of topical combined timolol and dorzolamide.
Topics: Adrenergic beta-Antagonists; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Cataract Extraction; Choroid Diseases; Chronic Disease; Drug Interactions; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Middle Aged; Ocular Hypotension; Ophthalmic Solutions; Prostaglandins F, Synthetic; Recurrence; Sulfonamides; Thiophenes; Timolol; Trabeculectomy | 2007 |
Reduced ocular allergy with fixed-combination 0.2% brimonidine-0.5% timolol.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Clinical Trials as Topic; Conjunctivitis, Allergic; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ocular Hypertension; Quinoxalines; Timolol | 2007 |
Aspergillus-induced malignant glaucoma.
Topics: Antihypertensive Agents; Aspergillosis; Aspergillus flavus; Corneal Ulcer; Eye Infections, Fungal; Female; Glaucoma; Humans; Intraocular Pressure; Keratoplasty, Penetrating; Middle Aged; Timolol | 2007 |
[Effect of the mixture of timoptol and amino acid taurine in the bioregulation of the intraocular pressure in rabbits].
Topics: Animals; Drug Combinations; Female; Intraocular Pressure; Rabbits; Taurine; Timolol | 2007 |
[Intraocular pressure (IOP) in rabbits after application of amino acids taurine and arginine with betablocker timolol].
Topics: Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Arginine; Drug Combinations; Female; Intraocular Pressure; Rabbits; Taurine; Timolol | 2007 |
Rabbit's intraocular pressure after instillation of timolol and aminoacid lysine, arginine, glycine or taurine mixture.
Topics: Amino Acids; Animals; Arginine; Drug Combinations; Female; Glaucoma; Glycine; Intraocular Pressure; Lysine; Rabbits; Taurine; Timolol | 2007 |
Comparative efficacy of pilocarpine, timolol and latanoprost in experimental models of glaucoma.
Topics: Adrenal Cortex Hormones; Animals; Anterior Chamber; Cholinergic Agonists; Conjunctival Diseases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Glaucoma; Instillation, Drug; Intraocular Pressure; Latanoprost; Male; Ophthalmic Solutions; Pilocarpine; Prednisolone; Prostaglandins F, Synthetic; Rabbits; Timolol; Tonometry, Ocular; Treatment Outcome | 2007 |
Topical WIN55212-2 alleviates intraocular hypertension in rats through a CB1 receptor mediated mechanism of action.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Benzoxazines; Blood Pressure; Calcium Channel Blockers; Camphanes; Heart Rate; Intraocular Pressure; Irritants; Male; Morpholines; Naphthalenes; Ocular Hypertension; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB1; Receptor, Cannabinoid, CB2; Rimonabant; Timolol | 2008 |
A cost-effectiveness analysis of fixed-combination therapies in patients with open-angle glaucoma: a European perspective.
Topics: Adrenergic beta-Antagonists; Amides; Antihypertensive Agents; Bimatoprost; Cloprostenol; Cost-Benefit Analysis; Decision Support Techniques; Drug Therapy, Combination; Europe; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Models, Economic; Prostaglandins F, Synthetic; Prostaglandins, Synthetic; Timolol; Travoprost | 2008 |
Normal-tension glaucoma.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aging; Brimonidine Tartrate; Circadian Rhythm; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Quinoxalines; Timolol; Visual Fields | 2008 |
New drug information. Combigan.
Topics: Antihypertensive Agents; Brimonidine Tartrate; Glaucoma; Humans; Intraocular Pressure; Quinoxalines; Timolol | 2008 |
Rebound tonometry in conscious, conditioned mice avoids the acute and profound effects of anesthesia on intraocular pressure.
Topics: Anesthesia, General; Anesthetics, Combined; Animals; Cross-Over Studies; Ethanol; Intraocular Pressure; Ketamine; Male; Mice; Ocular Hypotension; Reproducibility of Results; Time Factors; Timolol; Tonometry, Ocular; Xylazine | 2008 |
Ocular pharmacokinetic/pharmacodynamic modeling for timolol in rabbits using a telemetry system.
Topics: Adrenergic beta-Antagonists; Algorithms; Animals; Eye; Injections; Intraocular Pressure; Male; Rabbits; Telemetry; Timolol | 2008 |
Estimation of ocular rigidity based on measurement of pulse amplitude using pneumotonometry and fundus pulse using laser interferometry in glaucoma.
Topics: Aged; Blood Pressure; Drug Therapy, Combination; Female; Fundus Oculi; Glaucoma, Open-Angle; Humans; Interferometry; Intraocular Pressure; Lasers; Latanoprost; Light; Male; Middle Aged; Prostaglandins F, Synthetic; Pulse; Reference Values; Sulfonamides; Thiophenes; Timolol; Tonometry, Ocular | 2008 |
R-enantiomer of timolol: a potential selective ocular antihypertensive agent.
Topics: Animals; Aqueous Humor; Binding Sites; Bronchi; Chymotrypsin; Ciliary Body; Dihydroalprenolol; Dose-Response Relationship, Drug; Female; Glaucoma; Guinea Pigs; Humans; Intraocular Pressure; Iris; Male; Ocular Hypertension; Rabbits; Receptors, Adrenergic, beta; Time Factors; Timolol; Trachea | 1984 |
Adrenergic drugs and intraocular pressure: suppression of ocular hypertension induced by water loading.
Topics: Adrenergic beta-Antagonists; Animals; Butoxamine; Dobutamine; Ephedrine; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Metoprolol; Propranolol; Pupil; Rabbits; Sympathomimetics; Terbutaline; Timolol; Water | 1980 |
Pharmacology of ocular drugs. 1. Timolol maleate.
Topics: Adrenergic beta-Antagonists; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1980 |
Pharmacological effects of topical timolol in the rabbit eye.
Topics: Adrenergic beta-Antagonists; Animals; Ciliary Body; Cyclic AMP; Eye; In Vitro Techniques; Intraocular Pressure; Iris; Isoproterenol; Propanolamines; Rabbits; Timolol | 1980 |
Effects of selective beta 1- and beta 2-adrenoreceptor agonists and antagonists on intraocular pressure in the cat.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Atenolol; Carbachol; Cats; Dose-Response Relationship, Drug; Echothiophate Iodide; Eye; Female; Intraocular Pressure; Male; Sympathectomy; Timolol | 1981 |
Additive intraocular pressure reducing effect of topical timolol during systemic beta-blockade.
Topics: Administration, Oral; Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Alprenolol; Blood Pressure; Female; Humans; Intraocular Pressure; Male; Metoprolol; Middle Aged; Propanolamines; Timolol | 1982 |
Timolol maleate: side effects on healthy nonglaucomatous volunteers.
Topics: Adrenergic beta-Antagonists; Adult; Aerospace Medicine; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Israel; Male; Military Medicine; Propanolamines; Time Factors; Timolol | 1983 |
Treatment of ocular hypertension and glaucoma with dopamine antagonists.
Topics: Animals; Antipsychotic Agents; Butyrophenones; Dopamine Antagonists; Female; Glaucoma; Guinea Pigs; Haloperidol; Histamine Antagonists; Intraocular Pressure; Male; Muscle Relaxation; Myocardial Contraction; Ocular Hypertension; Rabbits; Timolol; Trifluperidol | 1984 |
ICI 118,551: an effective ocular hypotensive agent with selectivity for the ciliary process beta 2-adrenoceptor and with minimal cardiac side effects.
Topics: Adenylyl Cyclase Inhibitors; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Ciliary Body; Heart Rate; In Vitro Techniques; Intraocular Pressure; Isoproterenol; Lung; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Timolol | 1984 |
Catecholamines in aqueous humour of glaucoma patients.
Topics: Adrenergic Agonists; Aged; Animals; Aqueous Humor; Cataract; Catecholamines; Chronic Disease; Dopamine; Epinephrine; Glaucoma, Open-Angle; Haplorhini; Humans; Intraocular Pressure; Middle Aged; Norepinephrine; Timolol | 1984 |
Filtering valve implant for neovascular glaucoma in proliferative diabetic retinopathy.
Topics: Adult; Cryosurgery; Diabetic Retinopathy; Equipment Failure; Eye; Female; Filtration; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Lasers; Neovascularization, Pathologic; Timolol | 1982 |
Effects of pilocarpine, timolol, epifrin and thymoxamine on iris vessels in rhesus monkeys.
Topics: Animals; Blood Vessels; Epinephrine; Female; Fluorescein Angiography; Intraocular Pressure; Iris; Macaca mulatta; Moxisylyte; Pilocarpine; Pupil; Timolol | 1984 |
The effects of topically applied epinephrine and timolol on intraocular pressure and aqueous humor cyclic-AMP in the rabbit.
Topics: Animals; Aqueous Humor; Cyclic AMP; Epinephrine; Female; Intraocular Pressure; Propanolamines; Rabbits; Time Factors; Timolol | 1981 |
[Timolol response in denervational syndromes (author's transl)].
Topics: Fuchs' Endothelial Dystrophy; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Parasympathetic Nervous System; Propanolamines; Receptors, Adrenergic, beta; Timolol | 1981 |
The effect of hypotensive drugs on the intraocular pressure after waterloading in rabbits.
Topics: Acetazolamide; Animals; Antihypertensive Agents; Dronabinol; Epinephrine; Intraocular Pressure; Isoproterenol; Physostigmine; Pilocarpine; Rabbits; Time Factors; Timolol; Water | 1981 |
Effects of l- and d-timolol on cyclic AMP synthesis and intraocular pressure in water-loaded, albino and pigmented rabbits.
Topics: Animals; Cyclic AMP; Disease Models, Animal; Hemodynamics; Intraocular Pressure; Propanolamines; Rabbits; Stereoisomerism; Time Factors; Timolol; Urethane; Water Intoxication | 1983 |
Action mechanism of timolol to lower the intraocular pressure in rabbits.
Topics: Animals; Aqueous Humor; Catecholamines; Ciliary Body; Dinoprost; Dinoprostone; Dose-Response Relationship, Drug; Intraocular Pressure; Iris; Prostaglandins E; Prostaglandins F; Rabbits; Regional Blood Flow; Retinal Vessels; Sodium-Potassium-Exchanging ATPase; Timolol | 1983 |
Intraocular pressure following aphakic transplants.
Topics: Adult; Aged; Aphakia, Postcataract; Cataract Extraction; Corneal Transplantation; Humans; Intraocular Pressure; Lenses, Intraocular; Middle Aged; Timolol; Vitrectomy | 1983 |
Comparison of the ocular hypotensive efficacy of eicosanoids and related compounds.
Topics: Animals; Carbachol; Cats; Dinoprost; Dinoprostone; Epoprostenol; Female; Intraocular Pressure; Male; Prostaglandin D2; Prostaglandin Endoperoxides, Synthetic; Prostaglandins; Prostaglandins D; Prostaglandins E; Prostaglandins F; Prostaglandins F, Synthetic; Thiazoles; Thiazolidines; Timolol | 1984 |
Ocular injuries--treat or refer?
Topics: Acetazolamide; Adult; Burns, Chemical; Eye Injuries; Eyelids; Humans; Hyphema; Intraocular Pressure; Mannitol; Middle Aged; Optic Nerve Injuries; Physicians, Family; Referral and Consultation; Timolol; Visual Acuity; Wounds, Penetrating | 1983 |
Open-angle glaucoma: diagnosis and management.
Topics: Administration, Topical; Adult; Aqueous Humor; Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Microsurgery; Optic Nerve; Pilocarpine; Time Factors; Timolol; Tonometry, Ocular; Trabecular Meshwork; Visual Fields | 1983 |
[Study on aqueous humor dynamics: mechanism of the reduction of intraocular pressure by topical administration of timolol in the rabbit eye by means of the fluorescein concentration curve of the aqueous humor].
Topics: Administration, Topical; Animals; Aqueous Humor; Female; Fluoresceins; Intraocular Pressure; Male; Rabbits; Timolol | 1984 |
[Long-term effect of domestic timolol on patients with primary open-angle glaucoma].
Topics: Adolescent; Adult; Aged; Blood Pressure; Cornea; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Timolol; Visual Fields | 1984 |
Effect of topical epinephrine and timolol on ocular and optic nerve blood flow in phakic and aphakic rabbit eyes.
Topics: Animals; Aphakia; Choroid; Ciliary Body; Epinephrine; Eye; Female; Intraocular Pressure; Iris; Male; Optic Nerve; Rabbits; Regional Blood Flow; Retinal Vessels; Timolol | 1984 |
Effects of timolol on intraocular pressure following ocular adrenergic denervation.
Topics: Animals; Eye; Ganglia, Sympathetic; Intraocular Pressure; Rabbits; Receptors, Adrenergic; Timolol | 1984 |
Ultrastructural and pharmacologic studies on laser-induced glaucoma in primates and rabbits.
Topics: Animals; Disease Models, Animal; Epinephrine; Glaucoma; Indomethacin; Intraocular Pressure; Lasers; Macaca mulatta; Male; Rabbits; Time Factors; Timolol; Trabecular Meshwork | 1984 |
Forskolin lowers intraocular pressure by reducing aqueous inflow.
Topics: Adenylyl Cyclases; Animals; Aqueous Humor; Blood Pressure; Ciliary Body; Colforsin; Diterpenes; Dose-Response Relationship, Drug; Drug Synergism; Drug Tolerance; Female; Humans; In Vitro Techniques; Intraocular Pressure; Iris; Isoproterenol; Macaca; Male; Rabbits; Regional Blood Flow; Timolol | 1984 |
The effects of separate and combined topical treatment with timolol maleate and trifluormethazolamide on the intraocular pressure in normal rabbits.
Topics: Administration, Topical; Animals; Circadian Rhythm; Drug Synergism; Glaucoma; Humans; Intraocular Pressure; Male; Methazolamide; Rabbits; Thiadiazoles; Timolol | 1984 |
[Residual effect of timoptol in ocular hypertension].
Topics: Aged; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Time Factors; Timolol | 1983 |
Dopaminergic involvement in intraocular pressure in the rabbit eye.
Topics: Animals; Aqueous Humor; Ciliary Body; Dopamine; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Male; Rabbits; Reserpine; Timolol | 1983 |
Selective trabeculectomy. A report of a new surgical method for open angle glaucoma.
Topics: Acetazolamide; Aged; Anterior Chamber; Eye Diseases; Female; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Methods; Postoperative Complications; Timolol; Trabecular Meshwork | 1983 |
Drop attack in glaucoma. The Melbourne experience with topical miotics, adrenergic and neuronal blocking drops.
Topics: Echothiophate Iodide; Epinephrine; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Miotics; Ophthalmic Solutions; Pilocarpine; Timolol | 1983 |
Experience with dipivalyl epinephrine. Its effectiveness, alone or in combination, and its side effects.
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma; Glaucoma, Open-Angle; Headache; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1983 |
Safety and efficacy of timolol in pediatric glaucoma.
Topics: Adolescent; Adult; Child; Child, Preschool; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular Pressure; Male; Retrospective Studies; Timolol | 1983 |
Efficacy of combining timolol with other antiglaucoma medications.
Topics: Acetazolamide; Drug Therapy, Combination; Drug Tolerance; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Miotics; Timolol | 1983 |
Combined timolol and epinephrine therapy for open angle glaucoma.
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Pilocarpine; Random Allocation; Timolol | 1983 |
Cardiovascular effects of epinephrine and dipivefrin in patients using timolol: a single-dose study.
Topics: Aged; Aqueous Humor; Arrhythmias, Cardiac; Blood Pressure; Double-Blind Method; Drug Interactions; Drug Therapy, Combination; Epinephrine; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Middle Aged; Pupil; Random Allocation; Timolol | 1984 |
Intraocular pressure after intracapsular cataract extraction.
Topics: Aged; Anti-Bacterial Agents; Cataract Extraction; Chymotrypsin; Double-Blind Method; Female; Humans; Intraocular Pressure; Male; Middle Aged; Steroids; Timolol | 1984 |
Timolol and postoperative intraocular pressure.
Topics: Cataract Extraction; Humans; Intraocular Pressure; Lenses, Intraocular; Ocular Hypertension; Postoperative Care; Postoperative Complications; Timolol | 1984 |
The effect of d-timolol on intraocular pressure in patients with ocular hypertension.
Topics: Administration, Topical; Adult; Aged; Blood Pressure; Double-Blind Method; Drug Evaluation; Eye; Female; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Pupil; Random Allocation; Stereoisomerism; Timolol; Visual Acuity | 1984 |
Effect of indomethacin on the ocular hypotensive action of timolol maleate.
Topics: Double-Blind Method; Humans; Indomethacin; Intraocular Pressure; Ophthalmic Solutions; Random Allocation; Timolol | 1984 |
Does prostacyclin mediate alpha-adrenergic induced hypotension?
Topics: Animals; Aqueous Humor; Epinephrine; Epoprostenol; Indomethacin; Intraocular Pressure; Iris; Isoproterenol; Norepinephrine; Phenoxybenzamine; Rabbits; Timolol; Tranylcypromine | 1982 |
Ocular hypotensive effects of timolol in cat eyes.
Topics: Animals; Aqueous Humor; Carbon Radioisotopes; Carbonic Anhydrase Inhibitors; Carbonic Anhydrases; Cats; Female; Intraocular Pressure; Inulin; Male; Propanolamines; Timolol | 1980 |
[Effect of long-term administration of timolol eye drops in open-angle glaucoma (author's transl)].
Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Long-Term Care; Male; Middle Aged; Pilocarpine; Propanolamines; Timolol | 1980 |
[Long-term therapy with timolol for three years (author's transl)].
Topics: Acetazolamide; Carbachol; Drug Therapy, Combination; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Long-Term Care; Pilocarpine; Propanolamines; Timolol | 1981 |
[Preliminary report of clinical observation on reduction in intraocular pressure by timolol (author's transl)].
Topics: Adolescent; Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1982 |
[Evaluation of timolol in the treatment of glaucoma (author's transl)].
Topics: Adult; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1982 |
[A preliminary report on treatment of glaucoma with timolol (author's transl)].
Topics: Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1982 |
Visual field survival: the response to timolol therapy in open-angle glaucoma.
Topics: Aged; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Microcomputers; Middle Aged; Propanolamines; Timolol; Visual Field Tests; Visual Fields | 1983 |
Effects of pilocarpine, salbutamol, and timolol on aqueous humor formation in cynomolgus monkeys.
Topics: Albuterol; Animals; Aqueous Humor; Female; Fluoresceins; Intraocular Pressure; Macaca; Macaca fascicularis; Pentobarbital; Pilocarpine; Propanolamines; Time Factors; Timolol; Urethane | 1983 |
Ocular hypotensive action of labetalol in rabbit and human eyes.
Topics: Animals; Dose-Response Relationship, Drug; Ethanolamines; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Labetalol; Male; Ophthalmic Solutions; Pilocarpine; Propranolol; Rabbits; Timolol | 1981 |
Bullous keratopathy accompanying essential iris atrophy: response to lowered intraocular pressure.
Topics: Acetazolamide; Adult; Atrophy; Corneal Diseases; Female; Humans; Intraocular Pressure; Iris; Timolol | 1980 |
Continuous, simultaneous, and instant display of aqueous humor dynamics with a micro-spectrophotometer and a sensitive drop counter.
Topics: Acetazolamide; Animals; Aqueous Humor; Cats; Dye Dilution Technique; Female; Intraocular Pressure; Male; Methods; Pilocarpine; Spectrophotometry; Time Factors; Timolol | 1981 |
Acute suicidal depression associated with use of timolol.
Topics: Acute Disease; Aged; Depression; Female; Humans; Hyphema; Intraocular Pressure; Propanolamines; Timolol | 1982 |
The IOP-lowering effect of timolol in simple and capsular glaucoma. A multicenter study in Finland.
Topics: Acetazolamide; Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Finland; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Propanolamines; Timolol | 1982 |
Effect of myopia on prognosis in treated primary open-angle glaucoma.
Topics: Aged; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Myopia; Optic Disk; Prognosis; Timolol; Visual Fields | 1982 |
[Timolol effects in the rabbit eye (author's transl)].
Topics: Animals; Eye; Intraocular Pressure; Propanolamines; Rabbits; Timolol | 1982 |
Effect of chronically administered timolol on aqueous humor flow in patients with glaucoma.
Topics: Adult; Aged; Aqueous Humor; Drug Administration Schedule; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Propanolamines; Prospective Studies; Time Factors; Timolol | 1982 |
[Effects of timolol maleate on untreated contralateral eyes (author's transl)].
Topics: Adult; Aged; Cornea; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Pupil; Tears; Timolol | 1982 |
[A case of malignant glaucoma treated by vitrectomy].
Topics: Aged; Cataract Extraction; Cornea; Female; Glaucoma; Humans; Intraocular Pressure; Iris; Timolol; Tissue Adhesions; Vitreous Body | 1982 |
Argon laser trabeculoplasty: its effect on medical control of open-angle glaucoma.
Topics: Carbonic Anhydrase Inhibitors; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Prospective Studies; Timolol; Trabecular Meshwork | 1982 |
Effects of cholinergic drugs and adrenergic drugs on aqueous humor formation in the rabbit eye.
Topics: Albuterol; Animals; Aqueous Humor; Atropine; Epinephrine; Female; Intraocular Pressure; Isoproterenol; Male; Norepinephrine; Parasympathomimetics; Physostigmine; Pilocarpine; Propranolol; Rabbits; Sympathomimetics; Timolol | 1982 |
Timolol and dipivalyl epinephrine combination therapy.
Topics: Aged; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Propanolamines; Timolol | 1982 |
Timolol maleate and intra-ocular pressure in low-tension glaucoma.
Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1982 |
Comparison between pilocarpine and timolol on diurnal pressures in open-angle glaucoma.
Topics: Circadian Rhythm; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Timolol | 1980 |
Changing concepts in glaucoma.
Topics: Glaucoma; Humans; Intraocular Pressure; Middle Aged; Timolol | 1980 |
[Beta-receptor blocking agents and glaucoma; timolol in eye drops].
Topics: Blepharitis; Conjunctivitis; Glaucoma; Humans; Intraocular Pressure; Mental Disorders; Ophthalmic Solutions; Propanolamines; Timolol | 1981 |
[Local application of timolol is not a panacea in the management of glaucoma. Examples].
Topics: Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol; Trabecular Meshwork | 1980 |
[Infrared thermographic investigation of the mechanism of action of timolol (author's transl)].
Topics: Eye Diseases; Humans; Infrared Rays; Intraocular Pressure; Propanolamines; Thermography; Timolol | 1981 |
Long-term treatment with timolol ophthalmic solution in open-angle glaucoma.
Topics: Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Timolol | 1980 |
Timolol and pediatric glaucomas.
Topics: Adolescent; Adult; Child; Child, Preschool; Glaucoma; Humans; Infant; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Timolol | 1981 |
One-hour intraocular pressure response to timolol. Lack of correlation with long-term response.
Topics: Administration, Topical; Female; Humans; Intraocular Pressure; Male; Propanolamines; Time Factors; Timolol | 1981 |
[Tachyphylaxis in timolol therapy for chronic glaucoma (author's transl)].
Topics: Adolescent; Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Tachyphylaxis; Timolol | 1980 |
Fluorophotometric study of epinephrine and timolol in human subjects.
Topics: Aqueous Humor; Drug Therapy, Combination; Epinephrine; Fluoresceins; Glaucoma; Humans; Intraocular Pressure; Photometry; Propanolamines; Timolol | 1981 |
[Experiences with timolol use in cases of glaucoma (author's transl)].
Topics: Adolescent; Adult; Aged; Child; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1981 |
Drug effects on aqueous humor formation and pseudofacility in normal rabbit eyes.
Topics: Animals; Aqueous Humor; Atropine; Bradykinin; Dexamethasone; Dopamine; Intraocular Pressure; Melanocyte-Stimulating Hormones; Ouabain; Phenoxybenzamine; Prednisolone; Rabbits; Sotalol; Timolol | 1981 |
[Comparative clinical study of metoprolol and timolol (author's transl)].
Topics: Glaucoma; Humans; Intraocular Pressure; Metoprolol; Propanolamines; Time Factors; Timolol; Vasoconstriction | 1981 |
Aqueous humor dynamics in a series of patients with third neuron Horner's syndrome.
Topics: Adult; Aged; Aqueous Humor; Epinephrine; Female; Horner Syndrome; Humans; Intraocular Pressure; Male; Middle Aged; p-Hydroxyamphetamine; Timolol | 1981 |
Frequency of timolol administration.
Topics: Adult; Dose-Response Relationship, Drug; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Propanolamines; Timolol; Tonometry, Ocular; Visual Field Tests | 1981 |
Effects of long-term treatment with timolol on lacrimal gland function.
Topics: Adult; Aged; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lacrimal Apparatus; Male; Middle Aged; Muramidase; Propanolamines; Tears; Timolol | 1981 |
Effect of timolol maleate on intraocular pressure and pupil cycle time in normal eyes.
Topics: Administration, Topical; Adult; Drug Administration Schedule; Eye; Humans; Intraocular Pressure; Maleates; Propanolamines; Reflex, Pupillary; Timolol | 1981 |
[Comparative studies of the pressure-lowering effect of timolol and phospholine iodide (author's transl)].
Topics: Aged; Aphakia, Postcataract; Echothiophate Iodide; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1981 |
[Timolol versus Diamox (author's transl)].
Topics: Acetazolamide; Delayed-Action Preparations; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Timolol | 1981 |
Separate and combined effects of timolol maleate and acetazolamide in open-angle glaucoma.
Topics: Acetazolamide; Aged; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1981 |
Treatment of congenital glaucoma.
Topics: Acetazolamide; Amblyopia; Child, Preschool; Epinephrine; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular Pressure; Pilocarpine; Rubella; Timolol; Visual Acuity | 1981 |
Epinephrine and timolol: how do these drugs lower intraocular pressure?
Topics: Epinephrine; Humans; Intraocular Pressure; Propanolamines; Timolol | 1981 |
Timolol-maintenance treatment.
Topics: Aged; Eye Diseases; Female; Follow-Up Studies; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lens, Crystalline; Male; Middle Aged; Propanolamines; Timolol | 1980 |
[Ocular effects of epinephrine and timolol in normal volunteers (author's transl)].
Topics: Adult; Blood Pressure; Drug Therapy, Combination; Epinephrine; Female; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Propanolamines; Timolol | 1981 |
The effect of timolol maleate on the fellow eye.
Topics: Double-Blind Method; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Propanolamines; Timolol | 1980 |
Systemic effects of timolol.
Topics: Humans; Intraocular Pressure; Myasthenia Gravis; Propanolamines; Timolol | 1980 |
[Is it possible to use 0.1% timolol in the treatment of chronic glaucoma?].
Topics: Adult; Aged; Chronic Disease; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1980 |
[Our experience with timolol in the treatment of open-angle glaucoma].
Topics: Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1980 |
[Timolol Eyedrops].
Topics: Absorption; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Timolol | 1980 |
Beta blockers and glaucoma.
Topics: Animals; Aqueous Humor; Blood Pressure; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Rabbits; Timolol | 1980 |
Timolol in operated closed-angle glaucoma.
Topics: Epinephrine; Glaucoma; Humans; Intraocular Pressure; Iris; Male; Pilocarpine; Propanolamines; Timolol | 1980 |
Timolol eye drops: bradycardia or tachycardia?
Topics: Adult; Aged; Blood Pressure; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Pulse; Timolol | 1980 |
[Effect of timolol-epinephrine combination on intraocular pressure (author's transl)].
Topics: Adult; Aged; Chronic Disease; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1980 |
[Clinical experience in treatment of glaucoma with timolol (author's transl)].
Topics: Acetazolamide; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Timolol | 1980 |
[Timolol eyedrops in ophthalmological practice].
Topics: Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ophthalmic Solutions; Propanolamines; Sympathomimetics; Timolol | 1980 |
[Alteration of bronchial flow resistance due to timolol 0.25% in bronchial asthma (author's transl)].
Topics: Asthma; Bronchial Spasm; Female; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1980 |
[Timolol in simple glaucoma: action after one instillation of the drug (author's transl)].
Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1980 |
[Pressure-lowering effect of timolol in various forms of glaucoma (author's transl)].
Topics: Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1980 |
[Experience with timolol in consulting patients (author's transl)].
Topics: Clonidine; Drug Combinations; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Timolol | 1980 |
[Clinical treatment and long-term experience with timolol (author's transl)].
Topics: Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Propanolamines; Timolol | 1980 |
[Treatment of narrow-angle glaucoma with timolol (author's transl)].
Topics: Aged; Carbachol; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Propanolamines; Timolol | 1980 |
[Preliminary study of acidification of the pH of the aqueous humor in rats treated with timolol maleate].
Topics: Acid-Base Equilibrium; Animals; Aqueous Humor; Dose-Response Relationship, Drug; Hydrogen-Ion Concentration; Intraocular Pressure; Propanolamines; Rabbits; Timolol | 1980 |
Safety and effectiveness of concomitant administration of dipivefrin and timolol maleate.
Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1981 |
Posterior scleritis with annular ciliochoroidal detachment.
Topics: Adrenergic beta-Antagonists; Adult; Anti-Inflammatory Agents; Biopsy; Choroid Diseases; Ciliary Body; Eye Diseases; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Male; Muscarinic Agonists; Parotid Gland; Pilocarpine; Prednisone; Sarcoidosis; Scleritis; Timolol; Ultrasonography; Uveal Diseases | 1995 |
Medical and surgical aspects of congenital glaucoma.
Topics: Acetazolamide; Adrenergic Agonists; Adrenergic beta-Antagonists; Age Distribution; Child; Child, Preschool; Diuretics; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular Pressure; Iris; Male; Miotics; Pilocarpine; Timolol; Trabeculectomy | 1995 |
Optic nerve vasomotor effects of topical beta-adrenergic antagonists in rabbits.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Analysis of Variance; Animals; Arterioles; Betaxolol; Corrosion Casting; Female; Intraocular Pressure; Male; Microcirculation; Ophthalmic Solutions; Optic Nerve; Rabbits; Timolol; Vasoconstriction; Vasomotor System | 1995 |
Effects of timolol, terbutaline and forskolin on IOP, aqueous humour formation and ciliary cyclic AMP levels in the bovine eye.
Topics: 1-Methyl-3-isobutylxanthine; 8-Bromo Cyclic Adenosine Monophosphate; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Cattle; Cells, Cultured; Ciliary Body; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Epithelium; Intraocular Pressure; Perfusion; Phosphodiesterase Inhibitors; Terbutaline; Timolol | 1995 |
[Effect of topical timolol on microcirculation in the rabbit optic nerve head evaluated with a laser speckle microcirculation analyser].
Topics: Administration, Topical; Animals; Intraocular Pressure; Lasers; Microcirculation; Optic Disk; Rabbits; Random Allocation; Timolol | 1995 |
Superior cervical ganglionectomy in monkeys: aqueous humor dynamics and their responses to drugs.
Topics: Animals; Aqueous Humor; Dose-Response Relationship, Drug; Epinephrine; Female; Ganglionectomy; Intraocular Pressure; Ketamine; Macaca fascicularis; Pentobarbital; Pupil; Superior Cervical Ganglion; Timolol | 1995 |
Glaucoma associated with the nevus of Ota.
Topics: Anterior Eye Segment; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Nevus of Ota; Ophthalmic Solutions; Optic Disk; Sclera; Skin Neoplasms; Timolol | 1995 |
Oxygen-induced retinopathy in the newborn rat: effects of hyperbarism and topical administration of timolol maleate.
Topics: Administration, Topical; Animals; Animals, Newborn; Blood Pressure; Combined Modality Therapy; Disease Models, Animal; Humans; Hyperbaric Oxygenation; Infant, Newborn; Intraocular Pressure; Ophthalmic Solutions; Oxygen; Rats; Rats, Wistar; Retinal Neovascularization; Retinal Vessels; Retinopathy of Prematurity; Timolol | 1995 |
Controlled ocular timolol delivery: systemic absorption and intraocular pressure effects in humans.
Topics: Absorption; Aged; Drug Delivery Systems; Eye; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Silicones; Timolol | 1994 |
Clinical experience with a fixed dose combination therapy of timolol and pilocarpine used twice daily in the management of chronic open angle glaucoma.
Topics: Aged; Aged, 80 and over; Chronic Disease; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Prospective Studies; Timolol; Treatment Outcome | 1994 |
Topically effective ocular hypotensive acetazolamide and ethoxyzolamide formulations in rabbits.
Topics: 2-Hydroxypropyl-beta-cyclodextrin; Acetazolamide; Administration, Topical; Animals; beta-Cyclodextrins; Cyclodextrins; Drug Combinations; Ethoxzolamide; Female; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Timolol | 1994 |
Topical timolol, corneal epithelial permeability and autofluorescence in glaucoma by fluorophotometry.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Cell Membrane Permeability; Cornea; Epithelium; Fluorescence; Fluorophotometry; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1994 |
Intraocular pressure reduction with topically administered pilocarpine, timolol and betaxolol in normal tension glaucoma.
Topics: Administration, Topical; Aged; Aged, 80 and over; Analysis of Variance; Betaxolol; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Timolol | 1993 |
Effects of topical ethacrynic acid ointment vs timolol on intraocular pressure in glaucomatous monkey eyes.
Topics: Administration, Topical; Animals; Disease Models, Animal; Drug Administration Schedule; Ethacrynic Acid; Evaluation Studies as Topic; Female; Glaucoma; Intraocular Pressure; Laser Therapy; Longitudinal Studies; Macaca fascicularis; Ointments; Ophthalmic Solutions; Timolol; Trabecular Meshwork | 1994 |
Evidence of compromised circulation in the pathogenesis of optic nerve damage in chronic glaucomatous rabbit.
Topics: Animals; Chronic Disease; Drugs, Chinese Herbal; Female; Glaucoma; Intraocular Pressure; Male; Microcirculation; Optic Nerve; Plant Extracts; Rabbits; Retinal Ganglion Cells; Retinal Vessels; Salvia miltiorrhiza; Timolol | 1993 |
Visual field prognosis in early glaucoma. A long-term clinical follow-up.
Topics: Acetazolamide; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Ocular Hypertension; Optic Nerve Diseases; Pilocarpine; Prognosis; Retrospective Studies; Risk Factors; Timolol; Vision Disorders; Visual Fields | 1993 |
Doppler ultrasonography of the central retinal artery in normals treated with topical timolol.
Topics: Adult; Blood Flow Velocity; Diastole; Doppler Effect; Humans; Intraocular Pressure; Middle Aged; Retinal Artery; Systole; Timolol; Ultrasonography; Vasodilation | 1993 |
Transscleral neodymium:YAG laser cyclophotocoagulation for end-stage glaucoma, refractory glaucoma, and painful blind eyes.
Topics: Adult; Aged; Aged, 80 and over; Blindness; Ciliary Body; Epinephrine; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Laser Coagulation; Middle Aged; Pain; Postoperative Complications; Sclera; Timolol; Visual Acuity | 1993 |
Patient selection in the Timpilo Study.
Topics: Chronic Disease; Drug Therapy, Combination; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Research Design; Timolol | 1993 |
Colour Doppler velocimetry of the arterial vasculature of the optic nerve head and orbit.
Topics: Adult; Arteries; Female; Humans; Intraocular Pressure; Male; Middle Aged; Optic Disk; Orbit; Posture; Regional Blood Flow; Retinal Artery; Retinal Artery Occlusion; Rheology; Timolol; Ultrasonography | 1993 |
Can the concentration of timolol or the frequency of its administration be reduced?
Topics: Adult; Aged; Circadian Rhythm; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol | 1993 |
Preliminary evaluation of a series of amphiphilic timolol prodrugs: possible evidence for transscleral absorption.
Topics: Absorption; Animals; Cell Membrane Permeability; Cornea; Disease Models, Animal; Esters; Evaluation Studies as Topic; Intraocular Pressure; Isoproterenol; Ocular Hypertension; Pilot Projects; Prodrugs; Rabbits; Sclera; Solubility; Timolol | 1993 |
Evidence for a synergistic interaction between isoprenaline and timolol on intraocular pressure in conscious rabbits.
Topics: Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Intraocular Pressure; Isoproterenol; Rabbits; Receptors, Adrenergic, beta; Timolol | 1993 |
Aqueous humor flow and flare in patients with myotonic dystrophy.
Topics: Administration, Topical; Adult; Aged; Aqueous Humor; Circadian Rhythm; Female; Fluorophotometry; Hormones; Humans; Intraocular Pressure; Light; Male; Middle Aged; Myotonic Dystrophy; Ocular Hypotension; Scattering, Radiation; Timolol | 1993 |
Intraocular pressure reduction and systemic absorption of timolol after administration of one side-coated inserts in rabbits.
Topics: Absorption; Animals; Biological Availability; Drug Carriers; Drug Delivery Systems; Intraocular Pressure; Isoproterenol; Male; Ocular Hypotension; Ophthalmic Solutions; Rabbits; Tears; Timolol | 1993 |
Ophthalmic arachidonylethanolamide decreases intraocular pressure in normotensive rabbits.
Topics: Animals; Antihypertensive Agents; Arachidonic Acids; Cannabinoids; Endocannabinoids; Imidazoles; Intraocular Pressure; Medetomidine; Ocular Hypotension; Ocular Physiological Phenomena; Ophthalmic Solutions; Polyunsaturated Alkamides; Rabbits; Timolol | 1995 |
Drug effects on intraocular pressure and vascular flow in the bovine perfused eye using radiolabelled microspheres.
Topics: Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Carteolol; Cattle; Cerium Radioisotopes; Choroid; Ciliary Body; Eye; Intraocular Pressure; Iris; Microspheres; Nitroprusside; Perfusion; Regional Blood Flow; Timolol; Vasodilator Agents; Verapamil | 1995 |
Pattern electroretinogram in treated ocular hypertension: a cross-sectional study after timolol maleate therapy.
Topics: Adult; Aged; Antihypertensive Agents; Cross-Sectional Studies; Electroretinography; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Pattern Recognition, Visual; Retina; Timolol | 1995 |
Intraocular pressure after a two-week washout following long-term timolol or levobunolol.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Eye Color; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Levobunolol; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Retrospective Studies; Timolol; Tonometry, Ocular | 1995 |
Clinical analysis of steroid glaucoma.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Conjunctivitis, Allergic; Dexamethasone; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iritis; Male; Middle Aged; Pilocarpine; Prednisolone; Timolol; Visual Fields | 1995 |
Vaninolol: a novel compound for the treatment of glaucoma and ischemic retinopathy.
Topics: Adrenergic beta-Antagonists; Animals; Blood Flow Velocity; Butanones; Electroretinography; Eye; Female; Glaucoma; Intraocular Pressure; Ischemia; Male; Microspheres; Ocular Hypertension; Propanolamines; Rabbits; Rats; Retina; Retinal Artery; Retinal Artery Occlusion; Timolol | 1995 |
Transient myopia after pars plana vitrectomy.
Topics: Acetazolamide; Adult; Humans; Intraocular Pressure; Male; Myopia; Remission, Spontaneous; Retinal Detachment; Retinal Perforations; Time Factors; Timolol; Visual Acuity; Vitrectomy | 1996 |
Measurement of intraocular pressure by telemetry in conscious, unrestrained rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Blood Pressure; Circadian Rhythm; Consciousness; Female; Glucose; Heart Rate; Intraocular Pressure; Motor Activity; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Reproducibility of Results; Restraint, Physical; Telemetry; Timolol; Tonometry, Ocular | 1996 |
Essential thrombocythemia and central retinal vein occlusion with neovascular glaucoma.
Topics: Adrenergic beta-Antagonists; Antisickling Agents; Aspirin; Bone Marrow; Fluorescein Angiography; Fundus Oculi; Glaucoma, Neovascular; Humans; Hydroxyurea; Intraocular Pressure; Laser Coagulation; Male; Middle Aged; Neovascularization, Pathologic; Optic Disk; Platelet Aggregation Inhibitors; Platelet Count; Retinal Vein Occlusion; Thrombocythemia, Essential; Timolol | 1996 |
A complex interaction between topical verapamil and timolol on intraocular pressure in conscious rabbits.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug Synergism; Intraocular Pressure; Rabbits; Receptors, Adrenergic, beta; Timolol; Verapamil | 1996 |
Ocular mini-tablets for controlled release of timolol: evaluation in rabbits.
Topics: Absorption; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Area Under Curve; Delayed-Action Preparations; Drug Evaluation; Half-Life; Intraocular Pressure; Lacrimal Apparatus; Male; Ophthalmic Solutions; Rabbits; Tablets; Tears; Timolol | 1996 |
The usefulness of dapiprazole, an alpha-adrenergic blocking agent, in pigmentary glaucoma.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Adult; Aged; Chemotherapy, Adjuvant; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Piperazines; Prospective Studies; Timolol; Treatment Outcome; Triazoles | 1996 |
A topical prostaglandin for glaucoma.
Topics: Administration, Topical; Adrenergic Agents; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Cholinergic Agents; Clinical Trials as Topic; Drug Tolerance; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Latanoprost; Multicenter Studies as Topic; Parasympathomimetics; Pilocarpine; Prostaglandins F, Synthetic; Timolol | 1996 |
In vivo cAMP level in rabbit iris-ciliary body after topical epinephrine treatment.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Ciliary Body; Cyclic AMP; Dinoprostone; Disease Models, Animal; Drug Therapy, Combination; Epinephrine; Glaucoma; Intraocular Pressure; Iris; Laser Coagulation; Ophthalmic Solutions; Rabbits; Radioimmunoassay; Timolol; Yohimbine | 1996 |
Evaluation of multiple doses of 4 and 6% timolol, and timolol combined with 2% pilocarpine in clinically normal beagles and beagles with glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Evaluation; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Heart Rate; Intraocular Pressure; Male; Miotics; Ophthalmic Solutions; Pilocarpine; Pupil; Timolol; Tonometry, Ocular | 1995 |
Influence of diurnal variation on the intraocular pressure measurement of treated primary open-angle glaucoma during office hours.
Topics: Adrenergic beta-Antagonists; Aged; Appointments and Schedules; Circadian Rhythm; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Office Visits; Timolol; Tonometry, Ocular | 1996 |
Progressive normal-tension glaucoma. I. Analysis.
Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Aged; Disease Progression; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Timolol; Trabeculectomy; Visual Fields | 1996 |
Pharmacokinetics and intraocular pressure lowering effect of timolol preparations in rabbit eyes.
Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Biological Availability; Chromatography, High Pressure Liquid; Female; Gels; Glaucoma; Half-Life; Intraocular Pressure; Male; Ophthalmic Solutions; Rabbits; Timolol | 1996 |
Continuous intraocular pressure measurement by telemetry in alpha-chymotrypsin-induced glaucoma model in the rabbit: effects of timolol, dorzolamide, and epinephrine.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chymotrypsin; Circadian Rhythm; Disease Models, Animal; Epinephrine; Female; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol | 1996 |
Bilateral anterior uveitis associated with a brand of metipranolol.
Topics: Adrenergic beta-Antagonists; Aged; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Metipranolol; Recurrence; Timolol; Uveitis, Anterior | 1997 |
Effect of timolol on the diurnal intraocular pressure in exfoliation and primary open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Aged; Circadian Rhythm; Exfoliation Syndrome; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prospective Studies; Timolol | 1997 |
Effects of beta-blockers association with pilocarpine on rabbit intraocular pressure and heart rate.
Topics: Adrenergic beta-Antagonists; Animals; Drug Combinations; Heart Rate; Intraocular Pressure; Male; Metipranolol; Muscarinic Agonists; Ophthalmic Solutions; Pilocarpine; Rabbits; Timolol | 1997 |
Ocular-specific delivery of timolol by sequential bioactivation of its oxime and methoxime analogs.
Topics: Administration, Topical; Adrenergic beta-Agonists; Animals; Eye; Hydrolysis; Intraocular Pressure; Isoproterenol; Kinetics; Male; Rabbits; Rats; Rats, Sprague-Dawley; Tachycardia; Timolol | 1997 |
Effect of topical beta-blockers on tissue blood flow in the human optic nerve head.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Blood Flow Velocity; Blood Pressure; Carteolol; Heart Rate; Humans; Intraocular Pressure; Laser-Doppler Flowmetry; Ophthalmic Solutions; Optic Disk; Regional Blood Flow; Reproducibility of Results; Timolol | 1997 |
Treatment of progressive normal-tension glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Disease Progression; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Ophthalmic Solutions; Timolol; Trabeculectomy; Visual Acuity; Visual Fields | 1997 |
In vivo measurement of iridial circulation using laser speckle phenomenon.
Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Circulation; Blood Flow Velocity; Dinoprost; Intraocular Pressure; Iris; Lasers; Microspheres; Ophthalmic Solutions; Rabbits; Reproducibility of Results; Timolol | 1998 |
Five-year follow-up of treated patients with glaucoma using resolution perimetry.
Topics: Aged; Betaxolol; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Timolol; Treatment Outcome; Visual Acuity; Visual Field Tests; Visual Fields | 1998 |
Pharmacological evaluation of a new timolol/pilocarpine formulation.
Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Biological Availability; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Chymotrypsin; Intraocular Pressure; Muscarinic Agonists; Ocular Hypertension; Pilocarpine; Rabbits; Timolol | 1998 |
Acute glaucoma and acute corneal oedema in association with tularemia.
Topics: Acute Disease; Adrenergic beta-Antagonists; Anti-Infective Agents; Ciprofloxacin; Corneal Edema; Eye Infections, Bacterial; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Parasympathomimetics; Pilocarpine; Timolol; Tularemia | 1997 |
Effects of topical nipradilol, a beta-blocking agent with alpha-blocking and nitroglycerin-like activities, on aqueous humor dynamics and fundus circulation.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Aqueous Humor; Blood Circulation; Blood Flow Velocity; Blood-Aqueous Barrier; Capillary Permeability; Dose-Response Relationship, Drug; Fluorophotometry; Fundus Oculi; Intraocular Pressure; Nitroglycerin; Optic Disk; Propanolamines; Rabbits; Sclera; Timolol; Uvea; Vasodilator Agents | 1998 |
Influence of dorzolamide on corneal thickness, endothelial cell count and corneal sensibility.
Topics: Administration, Topical; Aged; Carbonic Anhydrase Inhibitors; Cell Count; Chronic Disease; Cornea; Drug Therapy, Combination; Endothelium, Corneal; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Sensation; Sulfonamides; Thiophenes; Timolol | 1998 |
The safety and efficacy of switching timolol maleate 0.5% solution to timolol hemihydrate 0.5% solution given twice daily.
Topics: Aged; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Solutions; Timolol | 1998 |
Ocular tension and pupil diameter effects of timolol 0.50% and pilocarpine 2% or 4% in association.
Topics: Adrenergic beta-Antagonists; Aged; Chronic Disease; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ocular Hypertension; Ophthalmic Solutions; Pilocarpine; Pupil; Timolol; Treatment Outcome | 1997 |
The effect of pneumoperitoneum on intraocular pressure in rabbits with alpha-chymotrypsin-induced glaucoma.
Topics: Adjuvants, Anesthesia; Administration, Topical; Anesthesia, General; Animals; Antihypertensive Agents; Blood Pressure; Body Temperature; Carbon Dioxide; Central Venous Pressure; Chymotrypsin; Disease Models, Animal; Glaucoma; Head-Down Tilt; Heart Rate; Insufflation; Intraocular Pressure; Male; Ocular Hypertension; Pentobarbital; Pneumoperitoneum, Artificial; Posture; Pressure; Rabbits; Reproducibility of Results; Time Factors; Timolol; Tonometry, Ocular | 1998 |
The effect of aqueous humor suppressants on intravitreal gas bubble duration in rabbits.
Topics: Absorption; Administration, Topical; Animals; Aqueous Humor; Clonidine; Fluorocarbons; Injections; Intraocular Pressure; Rabbits; Sulfonamides; Sulfur Hexafluoride; Thiophenes; Time Factors; Timolol; Vitreous Body | 1998 |
Glaucomatocyclitic crisis in a child.
Topics: Adolescent; Clonidine; Corneal Edema; Diagnosis, Differential; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Male; Pain; Prednisolone; Sulfonamides; Syndrome; Thiophenes; Timolol; Uveitis, Intermediate; Vision Disorders; Visual Acuity | 1998 |
A comparison of trabeculectomy with topically applied timolol in a rabbit ocular hypertension model.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Disease Models, Animal; Female; Fluorocarbons; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Timolol; Trabeculectomy; Treatment Outcome | 1998 |
An in-service investigation of the additive effect of topical adrenergic agonists and beta-blockers.
Topics: Administration, Topical; Adrenergic Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Betaxolol; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Timolol; Tonometry, Ocular | 1998 |
Discoidal niosome based controlled ocular delivery of timolol maleate.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Delayed-Action Preparations; Drug Delivery Systems; Eye; Female; Hydrogen-Ion Concentration; Intraocular Pressure; Male; Micelles; Polyethylene Glycols; Rabbits; Surface-Active Agents; Timolol | 1998 |
Intraocular pressure in rabbits by telemetry II: effects of animal handling and drugs.
Topics: Animal Husbandry; Animals; Circadian Rhythm; Clonidine; Epinephrine; Intraocular Pressure; Latanoprost; Ophthalmic Solutions; Pilocarpine; Prostaglandins F, Synthetic; Rabbits; Sulfonamides; Telemetry; Thiophenes; Timolol; Tonometry, Ocular | 1998 |
Immediate argon laser peripheral iridoplasty as treatment for acute attack of primary angle-closure glaucoma: a preliminary study.
Topics: Acute Disease; Administration, Topical; Aged; Aged, 80 and over; Anterior Eye Segment; Cohort Studies; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Ophthalmic Solutions; Pilocarpine; Prospective Studies; Timolol; Ultrasonography | 1998 |
Effects of timolol and betaxolol on choroidal blood flow in the rabbit.
Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Pressure; Choroid; Female; In Vitro Techniques; Intraocular Pressure; Laser-Doppler Flowmetry; Rabbits; Regional Blood Flow; Timolol; Vascular Resistance | 1998 |
[The influence of RS-Timolol in comparison with R-Timolol and S-Timolol on the intraocular pressure in water-loaded rabbits].
Topics: Adrenergic beta-Antagonists; Animals; Intraocular Pressure; Rabbits; Time Factors; Timolol | 1998 |
Timolol effects on aqueous humor dynamics in eyes of anesthetized rats.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Analysis of Variance; Anesthesia; Animals; Aqueous Humor; Blood Pressure; Cornea; Drug Administration Routes; Intraocular Pressure; Male; Ophthalmic Solutions; Rats; Rats, Sprague-Dawley; Timolol | 1999 |
Prolonged, contemporaneous administration of pilocarpine and timolol increases the aqueous humor pilocarpine levels in rabbits.
Topics: Absorption; Animals; Aqueous Humor; Drug Combinations; Hydrogen-Ion Concentration; Intraocular Pressure; Male; Pilocarpine; Rabbits; Timolol | 1999 |
Aqueous humor dynamics in alpha-chymotrypsin-induced ocular hypertensive rabbits.
Topics: Animals; Aqueous Humor; Chymotrypsin; Eye Proteins; Intraocular Pressure; Ocular Hypertension; Pilocarpine; Rabbits; Timolol; Tonometry, Ocular; Trabecular Meshwork | 1999 |
Dorzolamide-timolol combination versus concomitant administration of its components.
Topics: Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Humans; Intraocular Pressure; Sulfonamides; Thiophenes; Timolol | 1999 |
Effects of topical carteolol and timolol on tissue circulation in the iris and choroid.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Blood Circulation; Blood Flow Velocity; Carteolol; Choroid; Intraocular Pressure; Iris; Rabbits; Time Factors; Timolol; Vascular Resistance | 1999 |
The Hettinger hand vibration test, vasospasm, and glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Betaxolol; Diagnostic Techniques, Ophthalmological; Female; Follow-Up Studies; Glaucoma, Angle-Closure; Glaucoma, Open-Angle; Hand; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Optic Disk; Optic Neuropathy, Ischemic; Reproducibility of Results; Retinal Artery; Severity of Illness Index; Timolol; Vasoconstriction; Vibration | 1999 |
Marfan syndrome, lens subluxation, and open-angle glaucoma.
Topics: Acetazolamide; Adult; Cataract Extraction; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Lens Subluxation; Marfan Syndrome; Pilocarpine; Retinal Detachment; Risk Factors; Timolol | 1999 |
[Semi-annular pre-equatorial scleral ectasia in a patient with glaucoma and onchocerciasis].
Topics: Adult; Antihypertensive Agents; Dilatation, Pathologic; Glaucoma; Humans; Intraocular Pressure; Male; Onchocerciasis; Retinal Diseases; Scleral Diseases; Timolol; Visual Acuity | 1999 |
[Combined effect of topical latanoprost and timolol on retinal blood flow and tissue circulation in the optic nerve head in cynomolgus monkeys].
Topics: Animals; Female; Intraocular Pressure; Latanoprost; Macaca fascicularis; Male; Optic Disk; Prostaglandins F, Synthetic; Retinal Vessels; Timolol | 2000 |
Ophthaproblem. Acute angle-closure glaucoma.
Topics: Acetazolamide; Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibitors; Clonidine; Diagnosis, Differential; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Timolol | 2000 |
Oxygen-induced retinopathy in the newborn rat: morphological and immunohistological findings in animals treated with topical timolol maleate.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Animals, Newborn; Blood Pressure; Disease Models, Animal; Endothelial Growth Factors; Humans; Immunoenzyme Techniques; Infant, Newborn; Intraocular Pressure; Lymphokines; Oxygen; Rats; Rats, Wistar; Retinopathy of Prematurity; Timolol; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors | 2000 |
[Additive effect of pilocarpine and Timoptol on pupillary diameter and intraocular pressure in healthy rabbits].
Topics: Adrenergic beta-Antagonists; Animals; Drug Synergism; Intraocular Pressure; Male; Miotics; Pilocarpine; Pupil; Rabbits; Timolol | 2000 |
Latanoprost: new preparation. Antiglaucoma eye drops that can change the colour of the iris.
Topics: Acetazolamide; Clinical Trials as Topic; Drug Combinations; Epinephrine; Eye Color; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Prostaglandins F, Synthetic; Timolol; Treatment Outcome | 1998 |
Timolol lowers intraocular pressure but does not inhibit the development of experimental myopia in chick.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Chickens; Disease Models, Animal; Intraocular Pressure; Male; Myopia; Time Factors; Timolol; Treatment Failure | 2000 |
Effect of SR121463, a selective non-peptide vasopressin V2 receptor antagonist, in a rabbit model of ocular hypertension.
Topics: Administration, Oral; Administration, Topical; Animals; Antidiuretic Hormone Receptor Antagonists; Cell Membrane; Clonidine; Disease Models, Animal; Injections, Intravenous; Intraocular Pressure; Kidney; Male; Morpholines; Ocular Hypertension; Rabbits; Receptors, Vasopressin; Safety; Spiro Compounds; Timolol | 2000 |
Comparison of the ocular hypotensive effect of brimonidine, dorzolamide, latanoprost, or artificial tears added to timolol in glaucomatous monkey eyes.
Topics: Animals; Antihypertensive Agents; Brimonidine Tartrate; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma; Intraocular Pressure; Latanoprost; Macaca fascicularis; Ophthalmic Solutions; Prostaglandins F, Synthetic; Quinoxalines; Random Allocation; Sulfonamides; Thiophenes; Timolol | 2000 |
Xyloglucan as a novel vehicle for timolol: pharmacokinetics and pressure lowering activity in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Anterior Eye Segment; Aqueous Humor; Area Under Curve; Biological Availability; Chromatography, High Pressure Liquid; Ciliary Body; Cornea; Drug Delivery Systems; Female; Glucans; Intraocular Pressure; Iris; Male; Pharmaceutical Vehicles; Polysaccharides; Rabbits; Tears; Timolol; Tissue Distribution; Xylans | 2000 |
Development of glaucoma after phacoemulsification for removal of cataracts in dogs: 22 cases (1987-1997).
Topics: Animals; Antihypertensive Agents; Cataract; Dog Diseases; Dogs; Epinephrine; Female; Glaucoma; Intraocular Pressure; Male; Phacoemulsification; Retrospective Studies; Risk Factors; Timolol; Tonometry, Ocular; Uveitis | 2001 |
Effect of latanoprost and timolol on the histopathology of the rabbit conjunctiva.
Topics: Animals; Antihypertensive Agents; Collagen; Conjunctiva; Drug Combinations; Extracellular Matrix; Female; Immunoenzyme Techniques; Intraocular Pressure; Latanoprost; Matrix Metalloproteinase 3; Prostaglandins F, Synthetic; Rabbits; Timolol; Tissue Inhibitor of Metalloproteinase-2; Up-Regulation | 2001 |
Preliminary results of a study of the follow-up of nine glaucomatous patients treated with preservative-free eye drops.
Topics: Adrenergic beta-Antagonists; Follow-Up Studies; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Preservatives, Pharmaceutical; Tears; Timolol | 2000 |
Immediate diode laser peripheral iridoplasty as treatment of acute attack of primary angle closure glaucoma: a preliminary study.
Topics: Acute Disease; Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Clonidine; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Miotics; Pilocarpine; Timolol; Tonometry, Ocular; Treatment Outcome | 2001 |
Enhanced ocular hypotensive response to timolol in rabbits with prior dexamethasone treatment.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Anti-Inflammatory Agents; Dexamethasone; Dose-Response Relationship, Drug; Drug Synergism; Glucocorticoids; Intraocular Pressure; Male; Ocular Hypotension; Rabbits; Timolol | 2001 |
Effect of topical administration of 2% dorzlamide hydrochloride or 2% dorzlamide hydrochloride-0.5% timolol maleate on intraocular pressure in clinically normal horses.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Chemistry, Pharmaceutical; Drug Combinations; Female; Horses; Intraocular Pressure; Male; Random Allocation; Regression Analysis; Sulfonamides; Thiophenes; Timolol | 2001 |
Case reports and small case series: LASIK-associated visual field loss in a glaucoma suspect.
Topics: Cornea; Female; Humans; Intraocular Pressure; Keratomileusis, Laser In Situ; Latanoprost; Middle Aged; Myopia; Ocular Hypertension; Prostaglandins F, Synthetic; Timolol; Vision Disorders; Visual Acuity; Visual Fields | 2001 |
[Analysis of glaucoma therapy costs in Poland. I--population of the Mazovian District].
Topics: Adult; Aged; Aged, 80 and over; Costs and Cost Analysis; Disease Progression; Female; Glaucoma; Humans; Intraocular Pressure; Laser Therapy; Male; Middle Aged; Office Visits; Pilocarpine; Poland; Sulfonamides; Thiophenes; Timolol | 2000 |
Topical ocular instillation of nitric oxide synthase inhibitors and intraocular pressure in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Enzyme Inhibitors; Indazoles; Intraocular Pressure; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Ophthalmic Solutions; Rabbits; Thiazines; Timolol | 2001 |
Reliable measurement of mouse intraocular pressure by a servo-null micropipette system.
Topics: Acetazolamide; Anesthetics, Local; Animals; Aqueous Humor; Electrophysiology; Female; Intraocular Pressure; Latanoprost; Male; Mice; Ophthalmology; Pilocarpine; Prostaglandins F, Synthetic; Reproducibility of Results; Timolol | 2001 |
Systemic beta-blocker therapy and brimonidine and timolol.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Brimonidine Tartrate; Clinical Trials as Topic; Glaucoma, Open-Angle; Hemodynamics; Humans; Intraocular Pressure; Ocular Hypertension; Ophthalmic Solutions; Quinoxalines; Safety; Timolol | 2001 |
[Additive effects of topical carbonic anhydrase inhibitors].
Topics: Aged; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Synergism; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Male; Middle Aged; Pilocarpine; Prospective Studies; Prostaglandins F, Synthetic; Sulfonamides; Thiophenes; Timolol | 2001 |
Juvenile xanthogranuloma: concurrent involvement of skin and eye.
Topics: Acetazolamide; Atropine; Betamethasone; Drug Therapy, Combination; Eye Diseases; Humans; Infant; Intraocular Pressure; Male; Skin Diseases; Timolol; Xanthogranuloma, Juvenile | 2001 |
Timolol increased retrobulbar flow velocities in untreated glaucoma eyes but not in ocular hypertension.
Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Blood Flow Velocity; Blood Pressure; Female; Glaucoma, Open-Angle; Homeostasis; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Ophthalmic Artery; Ophthalmic Solutions; Retinal Artery; Timolol; Ultrasonography, Doppler, Color | 2001 |
Neuroprotection of retinal ganglion cells by brimonidine in rats with laser-induced chronic ocular hypertension.
Topics: Adrenergic alpha-Agonists; Adrenergic beta-Antagonists; Animals; Brimonidine Tartrate; Cell Survival; Chronic Disease; Cytoprotection; Glial Fibrillary Acidic Protein; Intraocular Pressure; Laser Coagulation; Male; Neuroprotective Agents; Ocular Hypertension; Quinoxalines; Rats; Rats, Wistar; Retina; Retinal Ganglion Cells; Time Factors; Timolol | 2001 |
[Innovative glaucoma therapy. Glaucoma therapy with topical carbonic anhydrase inhibitors].
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Carbonic Anhydrase Inhibitors; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Rabbits; Sulfonamides; Thiazines; Thiophenes; Time Factors; Timolol | 2001 |
Efficacy and safety of immediate anterior chamber paracentesis in the treatment of acute primary angle-closure glaucoma: a pilot study.
Topics: Acetazolamide; Acute Disease; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Anterior Chamber; Carbonic Anhydrase Inhibitors; Combined Modality Therapy; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Male; Mannitol; Middle Aged; Miotics; Paracentesis; Pilocarpine; Pilot Projects; Prospective Studies; Safety; Timolol; Visual Acuity | 2002 |
Long-term management of a glaucomatous eye in a dog treated with medical therapy alone.
Topics: Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibitors; Dichlorphenamide; Dog Diseases; Dogs; Glaucoma; Intraocular Pressure; Male; Timolol | 2001 |
The effect of topical CS-088, an angiotensin AT1 receptor antagonist, on intraocular pressure and aqueous humor dynamics in rabbits.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Aqueous Humor; Chymotrypsin; Disease Models, Animal; Imidazoles; Intraocular Pressure; Male; Ocular Hypertension; Ophthalmic Solutions; Rabbits; Receptor, Angiotensin, Type 1; Tetrazoles; Timolol | 2001 |
Short-term effect of beta-adrenoreceptor blocking agents on ocular blood flow.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Betaxolol; Blood Flow Velocity; Blood Pressure; Carteolol; Choroid; Ciliary Body; Eye; Heart Rate; Intraocular Pressure; Rabbits; Random Allocation; Regional Blood Flow; Retinal Vessels; Timolol; Vascular Resistance | 2001 |
Effects of a beta-adrenergic blocking agent timolol on intra ocular pressure responses induced by stimulation of cervical sympathetic nerve in the cat.
Topics: Adrenergic beta-Antagonists; Adrenergic Fibers; Animals; Cats; Cervical Vertebrae; Electric Stimulation; Eye; Intraocular Pressure; Timolol | 2001 |
Timolol concentrations in rat ocular tissues and plasma after topical and intraperitoneal dosing.
Topics: Absorption; Administration, Topical; Adrenergic beta-Antagonists; Animals; Antihypertensive Agents; Biological Availability; Chromatography, High Pressure Liquid; Eye; Injections, Intraperitoneal; Intraocular Pressure; Rats; Rats, Long-Evans; Timolol; Tissue Distribution | 2002 |
Travoprost compared with latanoprost and timolol in patients with open-angle glaucoma or ocular hypertension.
Topics: Antihypertensive Agents; Clinical Trials as Topic; Cloprostenol; Drug Evaluation; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Latanoprost; Ocular Hypertension; Prostaglandins F, Synthetic; Safety; Timolol; Travoprost | 2002 |
Bioavailability in the human eye of a fixed combination of latanoprost and timolol compared to monotherapy.
Topics: Absorption; Aged; Aqueous Humor; Biological Availability; Drug Combinations; Eye; Female; Half-Life; Humans; Intraocular Pressure; Latanoprost; Male; Prostaglandins F, Synthetic; Time Factors; Timolol | 2002 |
Effect of Xalatan(R) and Cosopt(R) on the vascular tone of quiescent isolated pig ciliary arteries.
Topics: Animals; Antihypertensive Agents; Ciliary Arteries; Culture Techniques; Dose-Response Relationship, Drug; Drug Combinations; Intraocular Pressure; Latanoprost; Potassium Chloride; Prostaglandins F, Synthetic; Sulfonamides; Swine; Thiophenes; Timolol; Vasoconstriction | 2002 |
Effect of hyaluronic acid on intraocular pressure in rats.
Topics: Animals; Anterior Chamber; Antihypertensive Agents; Brimonidine Tartrate; Disease Models, Animal; Hyaluronic Acid; Injections; Intraocular Pressure; Latanoprost; Male; Ocular Hypertension; Prostaglandins F, Synthetic; Quinoxalines; Rats; Rats, Wistar; Timolol; Tonometry, Ocular | 2002 |
An accurate comparison of bimatoprost's efficacy and adverse effects.
Topics: Amides; Antihypertensive Agents; Bimatoprost; Clinical Trials as Topic; Cloprostenol; Humans; Intraocular Pressure; Lipids; Ocular Hypertension; Safety; Timolol | 2002 |
Comparison of the effects of timolol and other adrenergic agents on intraocular pressure in the rabbit.
Topics: Adrenergic beta-Antagonists; Animals; Aqueous Humor; Chymotrypsin; Disease Models, Animal; Epinephrine; Intraocular Pressure; Isoproterenol; Male; Propanolamines; Propranolol; Rabbits; Sympathomimetics; Timolol; Water | 1977 |
beta-Blockers and the eye: an overview.
Topics: Adrenergic beta-Antagonists; Animals; Drug Synergism; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Ocular Physiological Phenomena; Ophthalmic Solutions; Propranolol; Rabbits; Timolol | 1978 |
[Studies on the mechanism of action of beta blocking agents on the intraocular pressure].
Topics: Adrenergic beta-Antagonists; Glaucoma; Humans; Intraocular Pressure; Timolol | 1977 |
Glaucoma treatment with timolol.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Drug Evaluation; Drug Therapy, Combination; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Propanolamines; Timolol | 1978 |
Trimolol: effect on intraocular pressure in chronic open-angle glaucoma.
Topics: Adrenergic beta-Antagonists; Dose-Response Relationship, Drug; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Propanolamines; Timolol | 1978 |
Timolol. Hypotensive effect, used alone and in combination for treatment of increased intraocular pressure.
Topics: Acetazolamide; Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Drug Tolerance; Epinephrine; Female; Glaucoma; Headache; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Propanolamines; Timolol | 1978 |
Comparison of the effects of nine beta-adrenergic blocking agents on intraocular pressure in rabbits.
Topics: Adrenergic beta-Antagonists; Animals; Atenolol; Drug Tolerance; Ethanolamines; Intraocular Pressure; Metoprolol; Oxprenolol; Pindolol; Practolol; Propranolol; Rabbits; Sotalol; Timolol | 1979 |
[The effect of timolol and parasympathicomimetica in the treatment of the elevated intraocular pressure (author's transl)].
Topics: Carbachol; Drug Administration Schedule; Glaucoma; Humans; Intraocular Pressure; Parasympathomimetics; Pilocarpine; Propanolamines; Quinuclidines; Timolol | 1979 |
The long-term hypotensive effect of timolol maleate compared with the effect of pilocarpine in simple and capsular glaucoma.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Drug Evaluation; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Miotics; Ophthalmic Solutions; Pilocarpine; Propanolamines; Time Factors; Timolol | 1979 |
The treatment of glaucoma: role of beta-blocking agents.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Atenolol; Glaucoma; Humans; Intraocular Pressure; Propranolol; Timolol | 1979 |
Hypotensive effect of timolol on secondary glaucoma in chronic uveitis.
Topics: Adolescent; Adult; Aged; Chronic Disease; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol; Uveitis | 1978 |
Beta blockers for glaucoma.
Topics: Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Propanolamines; Timolol | 1979 |
[Long-term study of the pressure-lowering effect of Timolol (author's transl)].
Topics: Adult; Aged; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Long-Term Care; Middle Aged; Propanolamines; Timolol | 1979 |
[Experimental studies with timolol: a new ocular hypotensive agent (author's transl)].
Topics: Animals; Aqueous Humor; Eye; Intraocular Pressure; Propanolamines; Rabbits; Timolol | 1978 |
[A new beta blocking agent in the treatment of chronic open-angle glaucoma: timolol maleate].
Topics: Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Time Factors; Timolol | 1978 |
[A single dose of maleate of timolol given orally: the effect on the ocular pressure (author's transl)].
Topics: Administration, Oral; Blood Pressure; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Pulse; Time Factors; Timolol | 1978 |
[Effect of daily instillations of timolol on the nycthemeral tension in subjects with chronic open-angle glaucoma (author's transl)].
Topics: Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Time Factors; Timolol | 1978 |
Pressure lowering effect of timolol with reference to its topical vascular action.
Topics: Administration, Topical; Adult; Aged; Drug Evaluation; Glaucoma; Hemodynamics; Humans; Hyperopia; Intraocular Pressure; Middle Aged; Propanolamines; Time Factors; Timolol | 1979 |
[Timolol and acetazolamide in the treatment of increased intraocular pressure (author's transl)].
Topics: Acetazolamide; Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1979 |
Timolol therapy in secondary angle-closure glaucoma post penetrating keratoplasty.
Topics: Carbonic Anhydrase Inhibitors; Corneal Transplantation; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Miotics; Postoperative Complications; Propanolamines; Timolol; Transplantation, Homologous | 1979 |
Timolol in the treatment of open angle glaucoma.
Topics: Administration, Topical; Chronic Disease; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1979 |
Apneic spells associated with timolol therapy in a neonate.
Topics: Acetazolamide; Apnea; Asphyxia Neonatorum; Cheyne-Stokes Respiration; Cryosurgery; Glaucoma; Humans; Infant, Newborn; Infant, Premature, Diseases; Intraocular Pressure; Propanolamines; Respiration Disorders; Timolol | 1979 |
Use of timolol.
Topics: Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1979 |
[Clinical experiences with timolol eye drops].
Topics: Adult; Aged; Drug Evaluation; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1979 |
Ocular hypotensive action of labetalol.
Topics: Animals; Ethanolamines; Female; Intraocular Pressure; Isoproterenol; Labetalol; Norepinephrine; p-Hydroxyamphetamine; Phenoxybenzamine; Pupil; Rabbits; Sympathectomy; Timolol | 1979 |
Evaluation of timolol maleate combination therapy in chronic open-angle glaucoma.
Topics: Acetazolamide; Adult; Aged; Carbachol; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Propanolamines; Timolol | 1979 |
[Timolol maleate. Pharmacology and review of the literature].
Topics: Acetazolamide; Aqueous Humor; Drug Synergism; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Propanolamines; Timolol | 1979 |
Timolol inhibition of aqueous humor production in the cat.
Topics: Acetylcholine; Animals; Aqueous Humor; Cats; Intraocular Pressure; Propanolamines; Time Factors; Timolol | 1979 |
Timolol maleate.
Topics: Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1979 |
Adverse effects experienced by patients taking timolol.
Topics: Aged; Asthma; Cardiovascular Diseases; Central Nervous System Diseases; Child; Eye Diseases; Female; Follow-Up Studies; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Respiratory Tract Diseases; Timolol; Vision Disorders | 1979 |
FDA warned timolol may be overprescribed.
Topics: Drug Utilization; Humans; Intraocular Pressure; Propanolamines; Timolol; United States; United States Food and Drug Administration | 1979 |
The effects of timolol on cataract extraction and intraocular pressure.
Topics: Cataract Extraction; Glaucoma; Humans; Intraocular Pressure; Lenses, Intraocular; Postoperative Complications; Propanolamines; Timolol | 1979 |
Timolol maleate in treatment of open angle glaucoma.
Topics: Adult; Aged; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Propanolamines; Timolol; Tonometry, Ocular | 1979 |
Management of acute closed-angle glaucoma with miotics and timolol.
Topics: Acetazolamide; Acute Disease; Adult; Aged; Drug Administration Schedule; Drug Therapy, Combination; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Pharmaceutical Vehicles; Pilocarpine; Propanolamines; Timolol | 1979 |
Effect of timolol on the permeability of corneal endothelium.
Topics: Adult; Cornea; Endothelium; Fluoresceins; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Permeability; Propanolamines; Timolol | 1979 |
Timolol--further observations.
Topics: Carbonic Anhydrase Inhibitors; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Miotics; Propanolamines; Tachyphylaxis; Timolol | 1979 |
Timolol: its effectiveness in different types of glaucoma.
Topics: Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1979 |
[Timolol (author's transl)].
Topics: Aged; Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Ophthalmic Solutions; Parasympathomimetics; Propanolamines; Time Factors; Timolol; Tonometry, Ocular; Visual Fields | 1979 |
Timolol in maintenance treatment of ocular hypertension and glaucoma.
Topics: Acetazolamide; Adult; Aged; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Propanolamines; Timolol; Visual Acuity; Visual Fields | 1979 |
[A follow-up study on the intraocular pressure response of timolol eye drops (author's transl)].
Topics: Adult; Aged; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Propanolamines; Timolol; Visual Fields | 1979 |
Intraocular pressure lowering effect of timolol in the fellow untreated eye.
Topics: Adult; Aged; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1979 |
Timolol: short term "escape" and long term "drift".
Topics: Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1979 |
Effect of timolol therapy on outflow facility.
Topics: Adult; Aged; Aqueous Humor; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1978 |
[The effect of timolol eye drops on the intraocular pressure in simple glaucoma (author's transl)].
Topics: Adult; Aged; Chemical Phenomena; Chemistry; Glaucoma; Humans; Intraocular Pressure; Middle Aged; Ophthalmic Solutions; Propanolamines; Timolol | 1978 |
A fluorophotometric study of the effect of topical timolol on aqueous humor dynamics.
Topics: Aqueous Humor; Depression, Chemical; Fluorometry; Humans; Intraocular Pressure; Propanolamines; Timolol | 1978 |
Timolol: new antiglaucoma agent works by a different mechanism.
Topics: Aqueous Humor; Chemical Phenomena; Chemistry; Drug Tolerance; Glaucoma; Humans; Intraocular Pressure; Propanolamines; Timolol | 1979 |
Timolol and facility of outflow.
Topics: Aqueous Humor; Glaucoma; Humans; Intraocular Pressure; Placebos; Propanolamines; Timolol | 1977 |
Rabbits have a circadian rhythm of aqueous humor cyclic AMP.
Topics: 1-Methyl-3-isobutylxanthine; Animals; Aqueous Humor; Circadian Rhythm; Cyclic AMP; Dark Adaptation; Intraocular Pressure; Light; Male; Rabbits; Timolol | 1992 |
Current perspective on microfluctuations of accommodation.
Topics: Accommodation, Ocular; Blood Pressure; Double-Blind Method; Fixation, Ocular; Humans; Intraocular Pressure; Ocular Hypotension; Refractive Errors; Timolol | 1992 |
Long-term drift and timolol therapy: possible role for pulsed therapy.
Topics: Aged; Aged, 80 and over; Drug Administration Schedule; Epinephrine; Humans; Intraocular Pressure; Longitudinal Studies; Middle Aged; Ocular Hypertension; Timolol | 1992 |
Basal tear turnover and topical timolol in glaucoma patients and healthy controls by fluorophotometry.
Topics: Administration, Topical; Fluorophotometry; Glaucoma; Humans; Intraocular Pressure; Reference Values; Reproducibility of Results; Tears; Timolol | 1992 |
[Posner-Schlossman syndrome].
Topics: Adult; Combined Modality Therapy; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iridocyclitis; Laser Therapy; Male; Syndrome; Timolol; Trabeculectomy; Visual Acuity; Visual Fields | 1992 |
[Does timolol modify retinal hemodynamics in patients with normal pressure glaucoma?].
Topics: Adult; Aged; Blood Flow Velocity; Female; Glaucoma; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Retinal Vessels; Timolol | 1992 |
Reversal of poorly controlled glaucoma on diagnosis and treatment of hypothyroidism.
Topics: Female; Fundus Oculi; Glaucoma, Open-Angle; Hemorrhage; Humans; Hypothyroidism; Intraocular Pressure; Middle Aged; Optic Nerve Diseases; Pilocarpine; Thyroxine; Timolol; Visual Acuity; Visual Fields | 1992 |
[Effects of timolol and carteolol on ocular pulsatile blood flow].
Topics: Adult; Carteolol; Eye; Humans; Intraocular Pressure; Pulsatile Flow; Regional Blood Flow; Timolol | 1992 |
Glaucoma and the iridocorneal endothelial syndrome.
Topics: Adult; Aged; Corneal Diseases; Endothelium, Corneal; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Iris Diseases; Male; Middle Aged; Prevalence; Retrospective Studies; Syndrome; Timolol; Trabeculectomy; Treatment Outcome | 1992 |
Color Doppler ultrasound of orbital and optic nerve blood flow: effects of posture and timolol 0.5%.
Topics: Administration, Topical; Adult; Blood Flow Velocity; Blood Pressure; Female; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Artery; Optic Nerve; Orbit; Posture; Timolol; Ultrasonography | 1992 |
Delayed filtering bleb encapsulation.
Topics: Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle; Glucocorticoids; Humans; Intraocular Pressure; Middle Aged; Postoperative Complications; Timolol; Trabeculectomy; Uveitis, Anterior | 1992 |
Beta-adrenergic responsiveness of choroidal vasculature.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Animals; Autoradiography; Choroid; Female; Hemodynamics; Humans; Intraocular Pressure; Male; Middle Aged; Pigment Epithelium of Eye; Pindolol; Rabbits; Receptors, Adrenergic, beta; Retinal Vessels; Timolol | 1991 |
[Potentiation by promethazine of hypotensive effects of adrenergic drugs on intraocular pressure].
Topics: Adrenergic beta-Antagonists; Animals; Drug Synergism; Epinephrine; Intraocular Pressure; Promethazine; Rabbits; Time Factors; Timolol | 1991 |
[The effect of Inj. Salviae Miltiorrhizae Co. on the retrograde axoplasmic transport in the optic nerve of rabbits with chronic IOP elevation].
Topics: Animals; Axonal Transport; Drug Therapy, Combination; Drugs, Chinese Herbal; Female; Intraocular Pressure; Male; Ocular Hypertension; Optic Nerve; Plant Extracts; Rabbits; Salvia miltiorrhiza; Timolol | 1991 |
A study of aqueous humor formation in patients with cystic fibrosis.
Topics: Administration, Topical; Adult; Aqueous Humor; Circadian Rhythm; Cystic Fibrosis; Female; Fluorophotometry; Humans; Intraocular Pressure; Male; Timolol | 1992 |
Reduced severity of oxygen-induced retinopathy in the newborn rat after topical administration of timolol maleate. A preliminary study.
Topics: Administration, Topical; Animals; Animals, Newborn; Blood Pressure; Disease Models, Animal; Fundus Oculi; Humans; Infant, Newborn; Intraocular Pressure; Oxygen; Perfusion; Rats; Rats, Inbred Strains; Retinal Diseases; Retinal Vessels; Retinopathy of Prematurity; Timolol | 1991 |
Unusual deposits in the superficial corneal stroma following combined use of topical corticosteroid and beta-blocking medication.
Topics: Aged; Aged, 80 and over; Calcinosis; Calcium Phosphates; Cataract Extraction; Corneal Diseases; Corneal Stroma; Dexamethasone; Electron Probe Microanalysis; Female; Humans; Intraocular Pressure; Keratoplasty, Penetrating; Lenses, Intraocular; Male; Middle Aged; Prednisolone; Timolol | 1991 |
Glaucoma laser trial.
Topics: Clinical Trials as Topic; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Timolol; Trabeculectomy | 1991 |
Additivity of prostaglandin F2 alpha-1-isopropyl ester to timolol in glaucoma patients.
Topics: Adult; Aged; Dinoprost; Drug Administration Schedule; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Prognosis; Timolol | 1991 |
Effects of topical dihydroergocristine on intraocular pressure, aqueous humor dynamics and pupil diameter in conscious rabbits. A comparative study with timolol and pilocarpine.
Topics: Administration, Topical; Animals; Aqueous Humor; Consciousness; Dihydroergotoxine; Intraocular Pressure; Miosis; Pilocarpine; Pupil; Rabbits; Timolol | 1991 |
Pharmacokinetic basis for nonadditivity of intraocular pressure lowering in timolol combinations.
Topics: Absorption; Administration, Topical; Animals; Anterior Eye Segment; Chromatography, High Pressure Liquid; Conjunctiva; Drug Combinations; Epinephrine; Eye Color; Intraocular Pressure; Lens, Crystalline; Pilocarpine; Rabbits; Sclera; Timolol; Tissue Distribution; Uvea | 1991 |
Systemic absorption of ocular timolol in poor and extensive metabolizers of debrisoquine.
Topics: Absorption; Adult; Blood; Debrisoquin; Female; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Polymorphism, Genetic; Radioligand Assay; Timolol | 1991 |
[Interaction of antiglaucomatous drugs and melanin granule].
Topics: Animals; Dinoprost; Dinoprostone; Drug Interactions; Epinephrine; Intraocular Pressure; Melanins; Pilocarpine; Propanolamines; Rabbits; Timolol | 1991 |
Treatment trials of glaucoma suspects.
Topics: Humans; Intraocular Pressure; Ocular Hypertension; Randomized Controlled Trials as Topic; Timolol; Visual Fields | 1991 |
Central cholinergic stimulation affects ocular functions through sympathetic pathways.
Topics: Animals; Atropine; Carbachol; Cerebral Ventricles; Epinephrine; Hexamethonium; Hexamethonium Compounds; Injections, Intraventricular; Intraocular Pressure; Norepinephrine; Pupil; Rabbits; Sympathectomy; Sympathetic Nervous System; Timolol | 1990 |
Postural studies in pulsatile ocular blood flow: II. Chronic open angle glaucoma.
Topics: Adult; Aged; Blood Pressure; Chronic Disease; Eye; Female; Glaucoma, Open-Angle; Heart Rate; Humans; Intraocular Pressure; Male; Middle Aged; Posture; Pulsatile Flow; Supination; Time Factors; Timolol | 1991 |
Effects of topical administration of timolol maleate on intraocular pressure and pupil size in dogs.
Topics: Administration, Topical; Animals; Dogs; Intraocular Pressure; Pupil; Timolol | 1991 |
Effects of topical administration of timolol maleate on intraocular pressure and pupil size in cats.
Topics: Administration, Topical; Animals; Cat Diseases; Cats; Female; Intraocular Pressure; Male; Miosis; Pupil; Time Factors; Timolol | 1991 |
Provocation and medical treatment in post-iridectomy glaucoma.
Topics: Administration, Topical; Adult; Aged; Dark Adaptation; Female; Glaucoma, Angle-Closure; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Pilocarpine; Prognosis; Timolol | 1990 |
The effects of timolol on intraocular pressure and exercise heart rate in poor and extensive debrisoquine metabolizers.
Topics: Adult; Debrisoquin; Electrocardiography; Exercise; Female; Heart Rate; Humans; Intraocular Pressure; Male; Phenotype; Timolol | 1990 |
[Ocular hypotensive action of l-stepholidine].
Topics: Animals; Aqueous Humor; Berberine; Carbonic Anhydrases; Intraocular Pressure; Mice; Pilocarpine; Pupil; Rabbits; Stereoisomerism; Timolol | 1990 |
[Changes in ocular hypotensive effect of griseolic acid with isoproterenol, timolol and melanin].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Depression, Chemical; Drug Synergism; Female; Intraocular Pressure; Isoproterenol; Male; Melanins; Rabbits; Timolol | 1990 |
Outpatient management of traumatic microhyphemas.
Topics: Adult; Ambulatory Care; Athletic Injuries; Atropine; Eye Injuries; Eye Protective Devices; Female; Follow-Up Studies; Humans; Hyphema; Intraocular Pressure; Male; Timolol; Visual Acuity | 1990 |
Effects of timolol on terbutaline- and VIP-stimulated aqueous humor flow in the cynomolgus monkey.
Topics: Animals; Aqueous Humor; Blood Pressure; Ciliary Body; Dose-Response Relationship, Drug; Drug Administration Routes; Female; Intraocular Pressure; Macaca fascicularis; Male; Terbutaline; Timolol; Vasoactive Intestinal Peptide | 1990 |
Effects of topical glaucoma drugs on fistulized rabbit conjunctiva.
Topics: Animals; Antibodies, Monoclonal; Cell Count; Cell Division; Conjunctiva; Double-Blind Method; Epinephrine; Fibroblasts; Fistula; Intraocular Pressure; Myosins; Ophthalmic Solutions; Pilocarpine; Rabbits; Sclera; Timolol | 1990 |
Timolol-pilocarpine combined vs timolol and pilocarpine given separately.
Topics: Drug Therapy, Combination; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Timolol | 1990 |
Flicker sensitivity in treated ocular hypertension.
Topics: Adult; Aged; Contrast Sensitivity; Female; Flicker Fusion; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Ocular Hypertension; Timolol; Visual Fields | 1990 |
Drop size and systemic adverse effects in timolol ophthalmic solution.
Topics: Blood Pressure; Female; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Male; Ophthalmic Solutions; Timolol | 1990 |
Timolol reduces IOP in normal NZW rabbits during the dark only.
Topics: Administration, Topical; Animals; Circadian Rhythm; Darkness; Dose-Response Relationship, Drug; Ganglia, Sympathetic; Ganglionectomy; Intraocular Pressure; Male; Rabbits; Reference Values; Timolol | 1990 |
Effects of D-timolol and L-timolol on ocular blood flow and intraocular pressure.
Topics: Administration, Topical; Animals; Choroid; Eye; Female; Injections, Intravenous; Intraocular Pressure; Male; Rabbits; Regional Blood Flow; Retinal Vessels; Stereoisomerism; Timolol | 1990 |
Primary argon laser trabeculoplasty after pretreatment with timolol. A safe and economic therapy of early glaucoma.
Topics: Aged; Aged, 80 and over; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Ocular Hypertension; Premedication; Prospective Studies; Timolol; Trabeculectomy | 1990 |
Topical timolol decreases plasma high-density lipoprotein cholesterol level.
Topics: Administration, Topical; Adult; Body Weight; Chi-Square Distribution; Cholesterol, HDL; Female; Humans; Intraocular Pressure; Lipids; Male; Middle Aged; Patient Compliance; Timolol | 1990 |
[The effect of adrenaline, pilocarpine and timolol on axoplasmic transport in the optic nerve. I. Findings in normotensive eyes].
Topics: Animals; Axonal Transport; Epinephrine; Female; Humans; Intraocular Pressure; Optic Nerve; Pilocarpine; Rats; Timolol | 1985 |
Anterior ischemic optic neuropathy and increased intraocular pressure.
Topics: Aged; Female; Glaucoma; Humans; Intraocular Pressure; Ischemia; Male; Middle Aged; Ocular Hypertension; Optic Disk; Optic Neuritis; Timolol; Visual Acuity | 1989 |
[Conservative treatment of glaucoma].
Topics: Acetazolamide; Clonidine; Drug Evaluation; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Moxisylyte; Parasympathomimetics; Timolol | 1989 |
The role of apraclonidine hydrochloride in laser therapy for glaucoma.
Topics: Acetazolamide; Adult; Aged; Animals; Clonidine; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Iris; Laser Therapy; Macaca fascicularis; Male; Middle Aged; Pilocarpine; Postoperative Complications; Timolol; Trabeculectomy | 1989 |
Cardiovascular and pulmonary effects of beta-blocking agents: implications for their use in ophthalmology.
Topics: Adrenergic beta-Antagonists; Age Factors; Betaxolol; Cardiovascular System; Drug Interactions; Glaucoma; Heart Diseases; Heart Rate; Humans; Intraocular Pressure; Lung; Lung Diseases; Propanolamines; Timolol | 1989 |
Pressure compliance test of the optic nerve head: influence of different antiglaucoma drugs.
Topics: Acetazolamide; Adrenergic beta-Antagonists; Betaxolol; Carteolol; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Pilocarpine; Propanolamines; Timolol | 1989 |
[An experimental study of the ocular hypotensive action of dopaminergic antagonists].
Topics: Animals; Dopamine Antagonists; Female; Haloperidol; Intraocular Pressure; Male; Pilocarpine; Rabbits; Timolol | 1989 |
The management of post-keratoplasty glaucoma by trabeculectomy.
Topics: Acetazolamide; Adult; Aged; Aged, 80 and over; Cataract Extraction; Chi-Square Distribution; Echothiophate Iodide; Female; Follow-Up Studies; Glaucoma; Humans; Intraocular Pressure; Keratoplasty, Penetrating; Male; Middle Aged; Pilocarpine; Prognosis; Risk Factors; Timolol; Trabeculectomy | 1989 |
Microvascular access to the uveal tract in the rabbit eye for ocular pharmacologic studies.
Topics: Animals; Catheterization, Peripheral; Dose-Response Relationship, Drug; Eye; Insulin; Intraocular Pressure; Microcirculation; Pharmaceutical Preparations; Pilocarpine; Rabbits; Timolol; Uvea | 1989 |
From timolol to betaxolol.
Topics: Adult; Aged; Betaxolol; Central Nervous System; Female; Humans; Intraocular Pressure; Male; Middle Aged; Propanolamines; Timolol | 1989 |
Effect of IOP on the visual field in ocuLar hypertension and glaucoma.
Topics: Glaucoma; Humans; Intraocular Pressure; Ocular Hypertension; Prognosis; Risk Factors; Timolol; Visual Fields | 1989 |
Computerized perimetric monitoring and study of scotomatous fluctuations in timolol-treated open-angle glaucoma patients.
Topics: Computers; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Longitudinal Studies; Middle Aged; Scotoma; Time Factors; Timolol; Visual Field Tests; Visual Fields | 1989 |
Ten-year follow-up of timolol-treated open-angle glaucoma.
Topics: Follow-Up Studies; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Optic Disk; Timolol; Visual Fields | 1989 |
[Use of the preparation optimol in treating primary glaucoma].
Topics: Drug Evaluation; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Timolol | 1989 |
Effect on the 24-hour diurnal curve of intraocular pressure of a fixed ratio combination of timolol 0.5% and pilocarpine 2% in patients with COAG not controlled on timolol 0.5%.
Topics: Aged; Chronic Disease; Drug Administration Schedule; Drug Combinations; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Pilocarpine; Time Factors; Timolol | 1989 |
Effects of stimulation of the ocular sympathetic nerves on IOP and aqueous humor flow.
Topics: Animals; Anterior Chamber; Aqueous Humor; Electric Stimulation; Eye; Female; Intraocular Pressure; Male; Phentolamine; Rabbits; Receptors, Adrenergic, alpha; Receptors, Adrenergic, beta; Sympathetic Nervous System; Timolol | 1987 |
Early post-operative pressure rise with ciliary body incarceration into Watson type trabeculectomy fistula.
Topics: Aged; Aged, 80 and over; Choroid; Ciliary Body; Eye Diseases; Female; Humans; Intraocular Pressure; Male; Reoperation; Timolol; Trabeculectomy; Uveal Diseases | 1987 |
Ocular hypotension in the rabbit. Receptor mechanisms of pirbuterol and nylidrin.
Topics: Adenylyl Cyclases; Adrenergic beta-Agonists; Animals; Aqueous Humor; Binding, Competitive; Ciliary Body; Cyclic AMP; Ethanolamines; Intraocular Pressure; Iris; Nylidrin; Rabbits; Receptors, Adrenergic, beta; Timolol | 1985 |
Are beta-adrenergic mechanisms involved in ocular hypotensive actions of adrenergic drugs?
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Albuterol; Animals; Aqueous Humor; Butoxamine; Cats; Dihydroalprenolol; Female; Intraocular Pressure; Male; Metoprolol; Propanolamines; Propranolol; Timolol | 1985 |
Comparison of the effects of adrenergic agonists and alpha-, beta 1-, beta 2-antagonists on the intraocular pressure and adenylate cyclase activity in the ciliary processes of the rabbit.
Topics: Acebutolol; Adenylyl Cyclases; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Ciliary Body; Intraocular Pressure; Isoproterenol; Labetalol; Metoprolol; Rats; Timolol; Water | 1985 |
Biochemical and physiological effects of S-32-468, a beta-adrenoceptor antagonist with possible oculoselectivity.
Topics: Adenylyl Cyclases; Adrenergic beta-Antagonists; Animals; Ciliary Body; Enzyme Activation; Humans; Intraocular Pressure; Isoproterenol; Lung; Male; Myocardium; Propanolamines; Rabbits; Timolol | 1985 |
Therapeutic and systemic side effects of ocular beta-adrenergic antagonists in anesthetized dogs.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dogs; Female; Heart Rate; Intraocular Pressure; Male; Propanolamines; Timolol | 1986 |
Drugs and glaucoma.
Topics: Adrenergic beta-Antagonists; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Implants; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Levobunolol; Pilocarpine; Propanolamines; Timolol | 1986 |
Pharmacological characterization of beta-adrenoceptor subtype involvement in the ocular hypotensive response to beta-adrenergic stimulation.
Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Animals; Dose-Response Relationship, Drug; Female; Intraocular Pressure; Isoproterenol; Male; Pindolol; Propanolamines; Rabbits; Receptors, Adrenergic, beta; Time Factors; Timolol | 1986 |
Topical timolol, at conventional, unilateral doses causes bilateral ocular beta-blockade in rabbits.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Animals; Blood Pressure; Dose-Response Relationship, Drug; Eye; Female; Heart Rate; Intraocular Pressure; Isoproterenol; Male; Rabbits; Time Factors; Timolol | 1987 |
[Comparative multicenter study of carteolol eyedrops with other beta blockers in 768 patients under normal conditions].
Topics: Adrenergic beta-Antagonists; Carteolol; Drug Evaluation; Glaucoma; Humans; Intraocular Pressure; Metipranolol; Ophthalmic Solutions; Pindolol; Propanolamines; Time Factors; Timolol | 1988 |
L-653,328: an ocular hypotensive agent with modest beta receptor blocking activity.
Topics: Adrenergic beta-Antagonists; Animals; Betaxolol; Ciliary Body; Dose-Response Relationship, Drug; Intraocular Pressure; Iodine Radioisotopes; Iodocyanopindolol; Iris; Ophthalmic Solutions; Pharmacology; Pindolol; Prodrugs; Propanolamines; Rabbits; Radioligand Assay; Receptors, Adrenergic, beta; Timolol | 1988 |
Ocular and cardiac beta-antagonism by timolol prodrugs, timolol and levobunolol.
Topics: Adrenergic beta-Antagonists; Animals; Eye; Heart; Heart Rate; Intraocular Pressure; Isoproterenol; Levobunolol; Male; Prodrugs; Rabbits; Timolol | 1988 |
Effects of topically applied falintolol: a new beta-adrenergic antagonist for treatment of glaucoma.
Topics: Administration, Topical; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Cattle; Cornea; Electrophysiology; Glaucoma; Heart Rate; Intraocular Pressure; Macaca fascicularis; Propanolamines; Pupil; Rabbits; Timolol | 1987 |
Intraocular pressure effects of timolol after unilateral instillation.
Topics: Adrenergic beta-Antagonists; Adult; Female; Glaucoma; Humans; Instillation, Drug; Intraocular Pressure; Male; Ophthalmic Solutions; Timolol; Tonometry, Ocular | 1988 |
[Systemic effects of beta blockaders used in collyria].
Topics: Bronchial Spasm; Glaucoma; Heart; Humans; Intraocular Pressure; Ophthalmic Solutions; Timolol | 1988 |
[Cyclic-nucleotides and adrenergic antiglaucoma drugs].
Topics: Animals; Aqueous Humor; Cyclic AMP; Cyclic GMP; Intraocular Pressure; Isoproterenol; Norepinephrine; Pupil; Rabbits; Timolol | 1985 |
Regulation of aqueous flow by the adenylate cyclase receptor complex in the ciliary epithelium.
Topics: Adenylyl Cyclases; ADP-Ribosylation Factors; Adult; Aged; Anterior Chamber; Aqueous Humor; Cell Membrane Permeability; Ciliary Body; Colforsin; Cyclic AMP; Diterpenes; Epithelium; Humans; Intraocular Pressure; Membrane Proteins; Middle Aged; Receptors, Adrenergic, beta; Timolol | 1985 |
Progressive herpetic corneal endotheliitis.
Topics: Acyclovir; Administration, Topical; Adult; Antigens, Viral; Drug Therapy, Combination; Endothelium; Female; Humans; Intraocular Pressure; Keratitis, Dendritic; Prednisolone; Simplexvirus; Timolol; Uveitis | 1985 |
The effect of ocular pigmentation on intraocular pressure response to timolol.
Topics: Adult; Aged; Female; Humans; Intraocular Pressure; Middle Aged; Ocular Physiological Phenomena; Pigmentation; Timolol | 1985 |
Aqueous production.
Topics: Animals; Aqueous Humor; Biological Transport, Active; Carbonic Anhydrases; Ciliary Body; Epinephrine; Humans; In Vitro Techniques; Intraocular Pressure; Membrane Potentials; Norepinephrine; Phentolamine; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase; Timolol; Vanadium; Water | 1986 |
Corneal decompensation following acute angle-closure glaucoma.
Topics: Acute Disease; Aged; Aged, 80 and over; Corneal Diseases; Corneal Transplantation; Edema; Female; Glaucoma; Humans; Intraocular Pressure; Lens, Crystalline; Male; Middle Aged; Postoperative Complications; Postoperative Period; Timolol; Vision, Ocular | 1988 |
[Long-term study of chronic glaucoma treated with beta blockers (timolol)].
Topics: Adult; Aged; Aged, 80 and over; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Long-Term Care; Middle Aged; Retrospective Studies; Timolol; Visual Acuity | 1987 |
Choroidal detachments induced by a systemic beta-blocker.
Topics: Aged; Choroid; Female; Humans; Intraocular Pressure; Timolol; Uveal Diseases | 1988 |
Ocular hypotensive effects of monoamine oxidase-A inhibitors in rabbit.
Topics: Animals; Drug Synergism; Epinephrine; Eye; Intraocular Pressure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Pupil; Rabbits; Time Factors; Timolol; Tissue Distribution | 1988 |
The accommodative response, refractive error and mental effort: 1. The sympathetic nervous system.
Topics: Accommodation, Ocular; Adult; Analysis of Variance; Humans; Intraocular Pressure; Male; Photic Stimulation; Refractive Errors; Sympathetic Nervous System; Thinking; Timolol | 1988 |
The effects of withdrawal of timolol in chronically treated glaucoma patients.
Topics: Adult; Aged; Aged, 80 and over; Aqueous Humor; Chronic Disease; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Middle Aged; Timolol | 1988 |
[Selected statistical measurement values].
Topics: Analysis of Variance; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Statistics as Topic; Timolol | 1988 |
[Comparison of 2 independent random samples and evaluating a theoretical distribution--2 variants of the Kolmogorov-Smirnov test].
Topics: Analysis of Variance; Biometry; Glaucoma; Humans; Intraocular Pressure; Pilocarpine; Reference Values; Timolol | 1988 |
[Lowering the intraocular pressure by a combination of timolol with adrenergic agents].
Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pressure; Ophthalmic Solutions; Prospective Studies; Timolol | 1988 |
Glaucoma in keratoplasty.
Topics: Acetazolamide; Corneal Transplantation; Glaucoma; Humans; Intraocular Pressure; Keratoconus; Lenses, Intraocular; Postoperative Complications; Postoperative Period; Timolol | 1988 |
[Morphologic studies of the anterior eye segment of the rat following long-term treatment with timolol].
Topics: Animals; Anterior Eye Segment; Aqueous Humor; Intraocular Pressure; Ophthalmic Solutions; Rats; Rats, Inbred Strains; Timolol | 1988 |
Dopamine-2 receptor blockade does not affect the ocular hypotensive action of timolol.
Topics: Adult; Female; Humans; Intraocular Pressure; Male; Metoclopramide; Receptors, Dopamine; Time Factors; Timolol | 1988 |
Effects of compound IS-35 on intraocular pressure.
Topics: Administration, Topical; Animals; Aqueous Humor; Berberine Alkaloids; Female; Intraocular Pressure; Male; Rabbits; Rats; Rats, Inbred Strains; Timolol; Tonometry, Ocular; Tretoquinol | 1988 |
The ocular effects of xylazine in rabbits, cats, and monkeys.
Topics: Animals; Cats; Cebus; Clonidine; Female; Intraocular Pressure; Male; Nictitating Membrane; Pupil; Rabbits; Sympathetic Nervous System; Thiazines; Timolol; Xylazine | 1986 |
Effect of timolol on intraocular pressure elevation following argon laser iridotomy.
Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Argon; Female; Humans; Intraocular Pressure; Iris; Laser Therapy; Male; Middle Aged; Time Factors; Timolol | 1987 |
Topical ocular hypotensive effects of the novel angiotensin converting enzyme inhibitor SCH 33861 in conscious rabbits.
Topics: Administration, Topical; Angiotensin-Converting Enzyme Inhibitors; Animals; Chemical Phenomena; Chemistry; Consciousness; Intraocular Pressure; Male; Phenylbutyrates; Rabbits; Spiro Compounds; Time Factors; Timolol | 1987 |
[Primary therapy of acute angle-block glaucoma].
Topics: Acetazolamide; Acute Disease; Drug Administration Schedule; Glaucoma; Humans; Infusions, Intravenous; Intraocular Pressure; Ophthalmic Solutions; Pilocarpine; Timolol | 1987 |
Chronic and recurrent choroidal detachment after glaucoma filtering surgery.
Topics: Acetazolamide; Aged; Aged, 80 and over; Choroid; Chronic Disease; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Methazolamide; Middle Aged; Postoperative Complications; Recurrence; Timolol; Uveal Diseases | 1987 |
Prevention of IOP-rise following Nd-YAG laser capsulotomy with pre-operative timolol eye-drops and 1 tablet acetazolamide 250 mg systematically.
Topics: Acetazolamide; Humans; Intraocular Pressure; Laser Therapy; Lens Capsule, Crystalline; Lens, Crystalline; Ophthalmic Solutions; Premedication; Timolol; Visual Acuity | 1986 |
[Timoptol in the after-care following argon laser trabeculoplasty].
Topics: Combined Modality Therapy; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Postoperative Complications; Timolol; Trabecular Meshwork | 1987 |
Management of increased intraocular pressure after cataract extraction.
Topics: Cataract Extraction; Humans; Intraocular Pressure; Postoperative Period; Timolol | 1987 |
Therapeutic response interactions between timolol maleate and dipivefrin hydrochloride.
Topics: Aged; Aged, 80 and over; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Ophthalmic Solutions; Timolol | 1987 |
Scintillating scotomas relieved with topical timolol.
Topics: Administration, Topical; Aged; Female; Humans; Intraocular Pressure; Scotoma; Timolol | 1987 |
The effect of timolol on anterior-chamber oxygenation.
Topics: Animals; Anterior Chamber; Cats; Intraocular Pressure; Oxygen; Partial Pressure; Timolol | 1987 |
Eyes or patients? Traps for the unwary in the statistical analysis of ophthalmological studies.
Topics: Data Interpretation, Statistical; False Positive Reactions; Humans; Intraocular Pressure; Nadolol; Random Allocation; Timolol | 1987 |
[Electro-tonography study of patients treated with Timoptic].
Topics: Female; Glaucoma; Humans; Intraocular Pressure; Male; Middle Aged; Timolol; Tonometry, Ocular | 1987 |
[Value of oculo-pression-tonometry in the determination of outflow resistance].
Topics: Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Timolol; Tonometry, Ocular | 1987 |
Bilateral effects of long-term monocular timolol therapy.
Topics: Adult; Aged; Aged, 80 and over; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Middle Aged; Time Factors; Timolol | 1987 |
Bilateral effects of monocular timolol treatment.
Topics: Eye; Humans; Intraocular Pressure; Male; Middle Aged; Timolol | 1986 |
[The effect of d-timolol on intraocular pressure in the normal subjects].
Topics: Humans; Intraocular Pressure; Timolol | 1986 |
Timolol and intra-ocular pressure elevation following neodymium: YAG laser surgery.
Topics: Aphakia, Postcataract; Cataract Extraction; Eye Diseases; Humans; Intraocular Pressure; Iris; Laser Therapy; Lasers; Premedication; Timolol | 1986 |
Effects of antiglaucoma drugs on the blood flow in rabbit eyes.
Topics: Animals; Blood Flow Velocity; Butyrophenones; Drug Evaluation, Preclinical; Eye; Glaucoma; Haloperidol; Intraocular Pressure; Pilocarpine; Rabbits; Timolol; Trifluperidol | 1986 |
Intraocular pressure effects of multiple doses of drugs applied to glaucomatous monkey eyes.
Topics: Animals; Drug Administration Schedule; Epinephrine; Glaucoma; Intraocular Pressure; Macaca fascicularis; Pilocarpine; Timolol | 1987 |
Intermediate-term changes in intraocular pressure after neodymium-YAG laser posterior capsulotomy.
Topics: Humans; Indomethacin; Intraocular Pressure; Lasers; Lens Capsule, Crystalline; Lens, Crystalline; Ophthalmic Solutions; Timolol | 1985 |
Three thousand YAG lasers in posterior capsulotomies: an analysis of complications and comparison to polishing and surgical discissions.
Topics: Acetazolamide; Cataract Extraction; Follow-Up Studies; Humans; Intraocular Pressure; Laser Therapy; Postoperative Care; Prednisolone; Time Factors; Timolol; Visual Acuity | 1985 |
Pharmacological testing in the laser-induced monkey glaucoma model.
Topics: Administration, Topical; Animals; Colforsin; Dinoprost; Diterpenes; Epinephrine; Glaucoma; Intraocular Pressure; Lasers; Macaca fascicularis; Pilocarpine; Prostaglandins F; Radiation Injuries, Experimental; Sodium Chloride; Timolol; Vanadates; Vanadium; Yohimbine | 1985 |
Effects of antiglaucoma drugs on [32P]orthophosphate incorporation into phospholipids of cat iris and ciliary process.
Topics: Animals; Atenolol; Carbachol; Cats; Ciliary Body; Intraocular Pressure; Iris; Phosphates; Phospholipids; Pilocarpine; Propranolol; Timolol | 1985 |
Attempt to arrest eye growth by means of ocular hypotony.
Topics: Animals; Eye; Intraocular Pressure; Timolol; Ultrasonography | 1985 |
[Results of 1-year use of local pindolol in open-angle glaucoma].
Topics: Glaucoma, Open-Angle; Humans; Intraocular Pressure; Ophthalmic Solutions; Pindolol; Timolol | 1985 |
Open angle glaucoma in melanosis oculi: response to laser trabeculoplasty.
Topics: Adolescent; Eye Diseases; Glaucoma, Open-Angle; Gonioscopy; Humans; Intraocular Pressure; Laser Therapy; Male; Melanosis; Ophthalmoscopy; Pilocarpine; Timolol; Trabecular Meshwork; Visual Acuity; Visual Fields | 1985 |
Pharmacological study on the effects of some ocular hypotensive drugs on aqueous humor formation in the arterially perfused enucleated rabbit eye.
Topics: Acetazolamide; Animals; Aqueous Humor; Arteries; Autonomic Agents; Dinitrophenols; Epinephrine; In Vitro Techniques; Intraocular Pressure; Isoproterenol; Ouabain; Perfusion; Pilocarpine; Rabbits; Time Factors; Timolol | 1985 |
[Is the use of beta receptor blockers in variously strong concentrations in the treatment of glaucoma sensible?].
Topics: Dose-Response Relationship, Drug; Glaucoma; Humans; Intraocular Pressure; Pindolol; Risk; Timolol | 1985 |
Clinical experience with timolol in childhood glaucoma.
Topics: Adolescent; Child; Child, Preschool; Drug Evaluation; Follow-Up Studies; Glaucoma; Humans; Infant; Infant, Newborn; Intraocular Pressure; Timolol | 1985 |
Blood flow in aphakic rabbit eyes after sub-chronic glaucoma drug treatment.
Topics: Animals; Aphakia; Choroid; Ciliary Body; Echothiophate Iodide; Epinephrine; Eye; Intraocular Pressure; Iris; Norepinephrine; Optic Nerve; Pilocarpine; Rabbits; Regional Blood Flow; Retinal Vessels; Timolol | 1985 |
Hypotony and ciliochoroidal detachment following pharmacologic aqueous suppressant therapy in previously filtered patients.
Topics: Acetazolamide; Aged; Choroid; Ciliary Body; Combined Modality Therapy; Drug Therapy, Combination; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Laser Therapy; Male; Postoperative Complications; Recurrence; Timolol; Trabecular Meshwork | 1985 |
[Evaluation of the effectiveness of beta blockers on the eye].
Topics: Adult; Blood Pressure; Humans; Intraocular Pressure; Optic Disk; Pindolol; Timolol | 1985 |
Secondary angle-closure glaucoma after central retinal vein occlusion.
Topics: Aged; Female; Fluorescein Angiography; Glaucoma; Humans; Intraocular Pressure; Male; Prednisolone; Retinal Diseases; Retinal Vein; Timolol | 1985 |
Timolol and pilocarpine are hypotensive in light-induced avian glaucoma.
Topics: Animals; Aqueous Humor; Chickens; Eye; Glaucoma; Injections, Intravenous; Intraocular Pressure; Light; Pilocarpine; Radiation Injuries, Experimental; Timolol | 1985 |
Human aqueous humor catecholamines.
Topics: Aged; Aqueous Humor; Cataract Extraction; Epinephrine; Female; Humans; Intraocular Pressure; Male; Middle Aged; Norepinephrine; Premedication; Timolol | 1985 |