tiludronic acid has been researched along with Bone Loss, Osteoclastic in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 24 (82.76) | 18.2507 |
| 2000's | 5 (17.24) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deleide, G; Fruttero, R; Gasco, A; Guenther, HL; Lazzarato, L; Lolli, ML; Rolando, B; Tron, GC | 1 |
| Alvarez, L; Ballesta, AM; Filella, X; Guañabens, N; Monegal, A; Muñoz-Gomez, J; Peris, P; Pons, F; Ros, I; Vidal, S | 1 |
| Denoix, JM; Riccio, B; Thibaud, D | 1 |
| Abe, M; Barbier, A; Murakami, H; Nakamura, T; Suzuki, K; Tsurukami, H | 1 |
| Arlot, ME; Delmas, PD; Meunier, PJ; Nilssen, MH; Pastoureau, P; Vergnaud, P | 1 |
| Audran, M; Basle, MF; Berard, E; Chappard, D; Mendoza-Sarmiento, J; Minaire, P; Picot, C; Privat, C; Rebel, A; Tournebise, H | 1 |
| Ammann, P; Bonjour, JP; Caverzasio, J; Rizzoli, R; Shigematsu, T; Slosman, D | 1 |
| Barbier, A; Murakami, H; Nakamura, I; Sasaki, T; Suda, T; Takahashi, N; Tanaka, S; Udagawa, N; Zhang, D | 1 |
| Ammann, P; Barbier, A; Bonjour, JP; Caverzasio, J; Rizzoli, R | 1 |
| Neer, RM | 1 |
| Goldstein, NH; McClung, MR; Picot, C; Tou, CK | 1 |
| Aguirre, C; de la Piedra, C; Díaz Curiel, M; Díaz Diego, EM; Díaz Martín, MA; López Gavilanes, E; Rapado, A | 1 |
| Barbier, A; Laroche, M; Ludot, I; Mazieres, B; Thiechart, M; Vernhet, C; Viguier, G | 1 |
| Barbier, A; Baron, R; David, P; Nguyen, H | 1 |
| de Bruin, H; Dingemanse, J; Jonkman, JH; Necciari, J; Peeters, PA; Schwietert, HR; Thiercelin, JF | 1 |
| Licata, AA | 1 |
| Andreassen, H; Bidstrup, M; Clemmesen, B; Gunnes, M; Ravn, P; Rix, M | 1 |
| Fleisch, HA | 1 |
| Abe, M; Barbier, A; Konno, F; Murakami, H; Nakajo, S; Nakamura, I; Nakaya, K; Suda, T; Takahashi, N; Tanaka, S; Udagawa, N; Yuda, Y | 1 |
| Auriola, S; Frith, J; Koivuniemi, A; Mönkkönen, J; Rogers, MJ | 1 |
| Handt, LK; Peter, CP; Smith, SM | 1 |
| Barbier, A; de Vernejoul, MC; Lacheretz, F; Martel, C; Mocaer, G; Morieux, C; Murakami, H; Nys, M; Tirode, F | 1 |
| Alexandre, C; Barbier, A; Barou, O; Lafage-Proust, MH; Laroche, N; Martel, C; Thomas, T; Tirode, F; Vico, L | 1 |
| Berger, Y; Briot, C; Caix, J; Davi, H; Simiand, J; Thiercelin, JF; Tronquet, C | 1 |
| Berenson, J; Hortobagyi, G; Lipton, A; Major, PP | 1 |
| Barbier, A; Bohic, S; Daculsi, G; Legrand, A; Martel, C; Rey, C; Rohanizadeh, R; Sfihi, H | 1 |
| Morales-Piga, A | 1 |
| Reginster, JY | 1 |
| Body, JJ; Dumon, JC; Magritte, A | 1 |
7 review(s) available for tiludronic acid and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Tiludronate: bone pharmacology and safety.
Topics: Animals; Biomechanical Phenomena; Bone Density; Bone Development; Bone Resorption; Diphosphonates; Disease Models, Animal; Dogs; Dose-Response Relationship, Drug; Fractures, Bone; Osteoblasts; Rats | 1995 |
Skeletal safety of tiludronate.
Topics: Animals; Bone Density; Bone Resorption; Calcium; Diphosphonates; Disease Models, Animal; Dogs; Drug Overdose; Humans; In Vitro Techniques; Osteitis Deformans; Papio; Rats; Species Specificity | 1995 |
Bisphosphonate therapy.
Topics: Alendronate; Animals; Bone Density; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Female; Fractures, Bone; Humans; Osteoclasts; Osteoporosis; Osteoporosis, Postmenopausal; Pamidronate; Risedronic Acid | 1997 |
Bisphosphonates: preclinical aspects and use in osteoporosis.
Topics: Alendronate; Animals; Bone Resorption; Clodronic Acid; Diphosphonates; Etidronic Acid; Humans; Osteoporosis; Pamidronate | 1997 |
Oral bisphosphonates: A review of clinical use in patients with bone metastases.
Topics: Alendronate; Biological Availability; Bone Density; Bone Neoplasms; Bone Resorption; Breast Neoplasms; Calcium; Clodronic Acid; Diphosphonates; Double-Blind Method; Etidronic Acid; Humans; Ibandronic Acid; Imidazoles; Male; Multiple Myeloma; Pamidronate; Prostatic Neoplasms; Pyridines; Randomized Controlled Trials as Topic; Risedronic Acid; Zoledronic Acid | 2000 |
Tiludronate. A new treatment for an old ailment: Paget's disease of bone.
Topics: Animals; Bone Resorption; Clinical Trials as Topic; Diphosphonates; Humans; Osteitis Deformans | 1999 |
Oral tiludronate: pharmacological properties and potential usefulness in Paget's disease of bone and osteoporosis.
Topics: Animals; Bone Diseases, Metabolic; Bone Resorption; Clinical Trials as Topic; Diphosphonates; Dogs; Drug Evaluation; Drug Tolerance; Female; Humans; Male; Mice; Osteitis Deformans; Osteoporosis, Postmenopausal; Papio; Rats; Tissue Distribution | 1992 |
6 trial(s) available for tiludronic acid and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Tiludronate as a new therapeutic agent in the treatment of navicular disease: a double-blind placebo-controlled clinical trial.
Topics: Animals; Bone Resorption; Diphosphonates; Dose-Response Relationship, Drug; Double-Blind Method; Female; Foot Diseases; Hoof and Claw; Horse Diseases; Horses; Injections, Intravenous; Lameness, Animal; Male; Osteitis; Treatment Outcome; Video Recording | 2003 |
Effects of tiludronate on bone loss in paraplegic patients.
Topics: Adolescent; Adult; Analysis of Variance; Biopsy; Bone Density; Bone Resorption; Diphosphonates; Double-Blind Method; Female; Humans; Ilium; Immobilization; Male; Middle Aged; Osteoclasts; Osteoporosis; Paraplegia; Spinal Cord Injuries | 1995 |
Tiludronate therapy for Paget's disease of bone.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Bone Resorption; Diphosphonates; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Osteitis Deformans | 1995 |
Multiple dose pharmacokinetics of tiludronate in healthy volunteers.
Topics: Adolescent; Adult; Bone Resorption; Calcium; Diphosphonates; Double-Blind Method; Drug Administration Schedule; Humans; Male; Phosphates | 1996 |
High bone turnover is associated with low bone mass and spinal fracture in postmenopausal women.
Topics: Aged; Aged, 80 and over; Biomarkers; Bone and Bones; Bone Density; Bone Development; Bone Resorption; Cross-Sectional Studies; Diphosphonates; Enzyme-Linked Immunosorbent Assay; Female; Humans; Immunoassay; Lumbar Vertebrae; Middle Aged; Osteocalcin; Osteoporosis, Postmenopausal; Reagent Kits, Diagnostic; Spinal Fractures; Thoracic Vertebrae | 1997 |
Efficacy and safety of the bisphosphonate tiludronate for the treatment of tumor-associated hypercalcemia.
Topics: Bone Resorption; Calcium; Diphosphonates; Fasting; Humans; Hypercalcemia; Kidney; Neoplasms; Phosphates | 1991 |
16 other study(ies) available for tiludronic acid and Bone Loss, Osteoclastic
| Article | Year |
|---|---|
Synthesis of NO-donor bisphosphonates and their in-vitro action on bone resorption.
Topics: Animals; Bone Resorption; Carrier Proteins; Cell Differentiation; Cell Line; Diphosphonates; Durapatite; Male; Membrane Glycoproteins; Mice; NF-kappa B; Nitric Oxide Donors; Osteoclasts; Radiopharmaceuticals; RANK Ligand; Rats; Receptor Activator of Nuclear Factor-kappa B; Sodium Pertechnetate Tc 99m; Stem Cells; Structure-Activity Relationship; Tissue Distribution | 2005 |
Serum osteoprotegerin and its ligand in Paget's disease of bone: relationship to disease activity and effect of treatment with bisphosphonates.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Bone and Bones; Bone Resorption; Carrier Proteins; Diphosphonates; Enzyme-Linked Immunosorbent Assay; Female; Glycoproteins; Humans; Interleukin-6; Male; Membrane Glycoproteins; Middle Aged; Osteitis Deformans; Osteoprotegerin; Postmenopause; Radionuclide Imaging; RANK Ligand; Receptor Activator of Nuclear Factor-kappa B; Receptors, Cytoplasmic and Nuclear; Receptors, Tumor Necrosis Factor | 2003 |
Effects of tiludronate on bone mass, structure, and turnover at the epiphyseal, primary, and secondary spongiosa in the proximal tibia of growing rats after sciatic neurectomy.
Topics: Administration, Oral; Animals; Biomarkers; Bone Density; Bone Diseases, Metabolic; Bone Resorption; Denervation; Diphosphonates; Dose-Response Relationship, Drug; Immobilization; Male; Microscopy, Fluorescence; Osteoclasts; Random Allocation; Rats; Rats, Sprague-Dawley; Sciatic Nerve; Staining and Labeling; Tibia; Tissue Embedding | 1994 |
The anabolic effect of human PTH (1-34) on bone formation is blunted when bone resorption is inhibited by the bisphosphonate tiludronate--is activated resorption a prerequisite for the in vivo effect of PTH on formation in a remodeling system?
Topics: Alkaline Phosphatase; Amino Acids; Analysis of Variance; Animals; Biomechanical Phenomena; Bone Density; Bone Development; Bone Resorption; Diphosphonates; Disease Models, Animal; Female; Humans; Hydroxyproline; Ilium; Injections, Subcutaneous; Osteocalcin; Osteoclasts; Osteoporosis, Postmenopausal; Parathyroid Hormone; Peptide Fragments; Sheep; Teriparatide | 1995 |
Effects of the bisphosphonate tiludronate on bone resorption, calcium balance, and bone mineral density.
Topics: Animals; Benzoates; Bone Density; Bone Resorption; Calcium; Diphosphonates; Dose-Response Relationship, Drug; Female; Humans; Intestinal Absorption; Male; Osteoporosis, Postmenopausal; Ovariectomy; Parathyroidectomy; Rats; Rats, Sprague-Dawley; Rats, Wistar; Retinoids; Thyroidectomy | 1993 |
A possible mechanism of the specific action of bisphosphonates on osteoclasts: tiludronate preferentially affects polarized osteoclasts having ruffled borders.
Topics: Animals; Bone Marrow; Bone Marrow Cells; Bone Resorption; Calcitriol; Cell Polarity; Cells, Cultured; Collagen; Diphosphonates; Dose-Response Relationship, Drug; Etidronic Acid; Giant Cells; Male; Mice; Mice, Inbred C57BL; Microscopy, Electron; Osteoblasts; Osteoclasts | 1995 |
Variable efficacy of bone remodeling biochemical markers in the management of patients with Paget's disease of bone treated with tiludronate.
Topics: Administration, Oral; Aged; Alkaline Phosphatase; Biomarkers; Bone Remodeling; Bone Resorption; Collagen; Collagen Type I; Creatinine; Diphosphonates; Female; Humans; Hydroxyproline; Male; Middle Aged; Osteitis Deformans; Osteocalcin; Peptide Fragments; Peptides; Procollagen | 1996 |
Effect of ovariectomy on intraosseous vascularization and bone remodelling in rats: action of tiludronate.
Topics: Animals; Blood Flow Velocity; Bone and Bones; Bone Remodeling; Bone Resorption; Capillaries; Diphosphonates; Estradiol; Female; Lumbar Vertebrae; Ovariectomy; Rats; Rats, Sprague-Dawley | 1996 |
The bisphosphonate tiludronate is a potent inhibitor of the osteoclast vacuolar H(+)-ATPase.
Topics: Alendronate; Animals; Binding, Competitive; Bone Resorption; Cell Membrane Permeability; Chickens; Diphosphonates; Dose-Response Relationship, Drug; Ethylmaleimide; Etidronic Acid; Female; Hydrogen-Ion Concentration; Kidney; Lethal Dose 50; Osteoclasts; Proton-Translocating ATPases; Saccharomyces cerevisiae; Synaptic Vesicles | 1996 |
Tiludronate inhibits protein tyrosine phosphatase activity in osteoclasts.
Topics: Actins; Animals; Bone Resorption; Cattle; Cells, Cultured; Cytoskeleton; Diphosphonates; Enzyme Inhibitors; Mice; Osteoclasts; Phosphotyrosine; Protein Tyrosine Phosphatases; Signal Transduction | 1997 |
Identification of adenine nucleotide-containing metabolites of bisphosphonate drugs using ion-pair liquid chromatography-electrospray mass spectrometry.
Topics: Adenine Nucleotides; Animals; Bone Resorption; Cell Line; Chromatography, High Pressure Liquid; Clodronic Acid; Diphosphonates; Etidronic Acid; Macrophages; Mass Spectrometry; Mice | 1997 |
Esophageal irritation due to alendronate sodium tablets: possible mechanisms.
Topics: Alendronate; Animals; Bone Resorption; Diphosphonates; Dogs; Esophagus; Etidronic Acid; Mucous Membrane; Risedronic Acid | 1998 |
The visualization and evaluation of bone architecture in the rat using three-dimensional X-ray microcomputed tomography.
Topics: Animals; Bone and Bones; Bone Resorption; Diphosphonates; Disease Models, Animal; Evaluation Studies as Topic; Female; Models, Anatomic; Osteoporosis; Ovariectomy; Rats; Rats, Sprague-Dawley; Spine; Tomography, X-Ray Computed | 1999 |
Bisphosphonate effects in rat unloaded hindlimb bone loss model: three-dimensional microcomputed tomographic, histomorphometric, and densitometric analyses.
Topics: Analysis of Variance; Animals; Body Weight; Bone Density; Bone Resorption; Densitometry; Diphosphonates; Dose-Response Relationship, Drug; Hindlimb; Humerus; Male; Rats; Rats, Wistar; Tibia; Tomography | 1999 |
Disposition of tiludronate (Skelid) in animals.
Topics: Aging; Animals; Blood Proteins; Bone and Bones; Bone Resorption; Diphosphonates; Dogs; Female; Food; Haplorhini; Intestinal Absorption; Male; Mice; Papio; Protein Binding; Rabbits; Rats; Tissue Distribution | 1999 |
Characterization of the trabecular rat bone mineral: effect of ovariectomy and bisphosphonate treatment.
Topics: Animals; Apatites; Bone Diseases, Metabolic; Bone Resorption; Calcium; Cholecalciferol; Diphosphonates; Disease Models, Animal; Female; Lumbar Vertebrae; Magnetic Resonance Spectroscopy; Ovariectomy; Parathyroid Hormone; Phosphorus; Phosphorus Radioisotopes; Rats; Rats, Sprague-Dawley; Spectroscopy, Fourier Transform Infrared; Weight Loss | 2000 |