tilorone has been researched along with Viral Diseases in 7 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two models, hamster and rabbit cornea, were selected for assays of protection afforded by tilorone dihydrochloride against herpes simplex (HSV) and vesicular stomatitis viruses (VSV)." | 7.65 | The mode of inhibition of herpes simplex and vesicular stomatitis ocular viral infections in the rabbit and hamster by an interferon inducer tilorone dihydrochloride. ( Tokumaru, T, 1975) |
| " Two models, hamster and rabbit cornea, were selected for assays of protection afforded by tilorone dihydrochloride against herpes simplex (HSV) and vesicular stomatitis viruses (VSV)." | 3.65 | The mode of inhibition of herpes simplex and vesicular stomatitis ocular viral infections in the rabbit and hamster by an interferon inducer tilorone dihydrochloride. ( Tokumaru, T, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stringfellow, DA | 3 |
| Aiuti, F | 1 |
| Montella, F | 1 |
| Selkova, EP | 1 |
| Tur'ianov, MC | 1 |
| Pantiukhova, TN | 1 |
| Nikitina, GI | 1 |
| Semenenko, TA | 1 |
| Tokumaru, T | 1 |
| German, A | 1 |
| Quero, AM | 1 |
1 review available for tilorone and Viral Diseases
| Article | Year |
|---|---|
[Interferon inducers].
Topics: Animals; Bacteria; Drug Tolerance; Humans; Interferon Inducers; Interferons; Mice; Mitogens; Nucleic | 1974 |
1 trial available for tilorone and Viral Diseases
| Article | Year |
|---|---|
[Evaluation of amixine reactivity and efficacy for prophylaxis of acute respiratory tract infections].
Topics: Antiviral Agents; Health Personnel; Humans; Respiratory Tract Infections; Tilorone; Virus Diseases | 2001 |
5 other studies available for tilorone and Viral Diseases
| Article | Year |
|---|---|
Antiviral and interferon-inducing properties of interferon inducers administered with prostaglandins.
Topics: Animals; Drug Synergism; Female; Friend murine leukemia virus; Interferon Inducers; Interferons; Leu | 1980 |
[Concepts of stimulating immunotherapy].
Topics: Adjuvants, Immunologic; Antiviral Agents; Ascorbic Acid; Bacterial Infections; Glucans; Humans; Hype | 1982 |
The mode of inhibition of herpes simplex and vesicular stomatitis ocular viral infections in the rabbit and hamster by an interferon inducer tilorone dihydrochloride.
Topics: Animals; Cornea; Cricetinae; Fluorenes; Herpes Simplex; Male; Rabbits; Stomatitis; Tilorone; Time Fa | 1975 |
Comparation interferon- inducing and antiviral properties of 2-amino-5-bromo-6-methyl-4-pyrimidinol (U-25,166), tilorone hydrochloride, and polyinosinic-polycytidylic acid.
Topics: Animals; Antiviral Agents; Female; Fluorenes; Interferon Inducers; Interferons; Mice; Poly I-C; Pyri | 1977 |
Interferon inducers as antiviral agents.
Topics: Animals; Diamines; Humans; Interferon Inducers; Mice; Poly I-C; Propylamines; Pyrimidines; Tilorone; | 1977 |