tilorone and Vaccinia
tilorone has been researched along with Vaccinia in 2 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
Vaccinia: The cutaneous and occasional systemic reactions associated with vaccination using smallpox (variola) vaccine.
Research Excerpts
| Excerpt | Relevance | Reference |
|---|---|---|
| "The antiviral effect of 3 derivatives of benzo(c)fluorenone against encephalomyocarditis (EMC) and vaccinia viruses in mice was compared with that of tilorone hydrochloride (THCl)." | 3.67 | Derivatives of benzo(c)fluorene. VI. Antiviral and interferon-inducing activities of three benzo(c)fluorenone derivatives in mice. ( Krepelka, J; Smejkal, F; Vancurová, I; Zelená, D, 1985) |
Research
Studies (2)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
Authors
| Authors | Studies |
|---|---|
| Ikeda, S | 1 |
| Matsuda, Y | 1 |
| Nishimura, C | 1 |
| Smejkal, F | 1 |
| Zelená, D | 1 |
| Krepelka, J | 1 |
| Vancurová, I | 1 |
Other Studies
2 other studies available for tilorone and Vaccinia
| Article | Year |
|---|---|
Enhancement by muramyldipeptides of the activities of early-type inducers of interferon.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Cell Line; Female; Interferon Inducers; Interferon-gamma | 1985 |
Derivatives of benzo(c)fluorene. VI. Antiviral and interferon-inducing activities of three benzo(c)fluorenone derivatives in mice.
Topics: Animals; Antiviral Agents; Encephalomyocarditis virus; Enterovirus Infections; Fluorenes; Interferon | 1985 |