tilorone has been researched along with Spinal Cord Diseases in 1 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
Spinal Cord Diseases: Pathologic conditions which feature SPINAL CORD damage or dysfunction, including disorders involving the meninges and perimeningeal spaces surrounding the spinal cord. Traumatic injuries, vascular diseases, infections, and inflammatory/autoimmune processes may affect the spinal cord.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Necrosis of the spinal cord was produced by administering tilorone to rats before or during the incubation period of experimental allergic encephalomyelitis (EAE)." | 7.65 | Necrotic myelopathy (myelomalacia) in rats with allergic encephalomyelitis treated with tilorone. ( Levine, S; Sowinski, R, 1976) |
| "Necrosis of the spinal cord was produced by administering tilorone to rats before or during the incubation period of experimental allergic encephalomyelitis (EAE)." | 3.65 | Necrotic myelopathy (myelomalacia) in rats with allergic encephalomyelitis treated with tilorone. ( Levine, S; Sowinski, R, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levine, S | 1 |
| Sowinski, R | 1 |
1 other study available for tilorone and Spinal Cord Diseases
| Article | Year |
|---|---|
Necrotic myelopathy (myelomalacia) in rats with allergic encephalomyelitis treated with tilorone.
Topics: Animals; Encephalomyelitis, Autoimmune, Experimental; Female; Fluorenes; Immunization, Passive; Immu | 1976 |