tilorone has been researched along with Shock, Septic in 2 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
Shock, Septic: Sepsis associated with HYPOTENSION or hypoperfusion despite adequate fluid resuscitation. Perfusion abnormalities may include but are not limited to LACTIC ACIDOSIS; OLIGURIA; or acute alteration in mental status.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Angelov, ET | 1 |
| Murat, J | 1 |
| Georgiev, N | 1 |
| Nicolov, N | 1 |
| Levine, S | 1 |
| Sowinski, R | 1 |
1 review available for tilorone and Shock, Septic
| Article | Year |
|---|---|
Endotoxin inhibitory effect on the liver cytochrome P-450-monooxygenase system.
Topics: Animals; Biotransformation; Child; Cytochrome P-450 Enzyme System; Depression, Chemical; Endotoxins; | 1983 |
1 other study available for tilorone and Shock, Septic
| Article | Year |
|---|---|
Endotoxin toxicity in rats is enhanced by tilorone.
Topics: Adrenalectomy; Animals; Drug Synergism; Endotoxins; Escherichia coli; Fluorenes; Intestine, Small; K | 1976 |