tilorone and Pregnancy studies

tilorone and Pregnancy

tilorone has been researched along with Pregnancy in 3 studies

Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

Excerpt	Relevance	Reference
" In experiment 4, tilorone (400 mg/kg) was administered on gestation day 17, 18, or 19, and the dams were killed 24 hr after dosing or on gestation day 20."	1.28	Prevention of tilorone developmental toxicity with progesterone. ( Hamilton, RD; Marks, TA; Pitts, TW; Renis, HE; Terry, RD, 1992)

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (33.33)	18.7374
1990's	2 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Timeframe

Studies, this research(%)

All Research%

pre-1990

1 (33.33)

18.7374

1990's

2 (66.67)

18.2507

2000's

0 (0.00)

29.6817

2010's

0 (0.00)

24.3611

2020's

0 (0.00)

2.80

Authors

Authors	Studies
Robbins, MS	1
Mannering, GJ	1
Marks, TA	2
Tracy, DE	1
Terry, RD	1
Hamilton, RD	1
Pitts, TW	1
Renis, HE	1

Studies

Robbins, MS

Mannering, GJ

Marks, TA

Tracy, DE

Terry, RD

Hamilton, RD

Pitts, TW

Renis, HE

Other Studies

3 other studies available for tilorone and Pregnancy

Article	Year
Effects of the interferon inducing agents tilorone and polyriboinosinic acid . polyribocytidylic acid (poly IC) on the hepatic monooxygenase systems of pregnant and fetal rats. Biochemical pharmacology, 1984, Apr-15, Volume: 33, Issue:8 Topics: Aminopyrine N-Demethylase; Animals; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Dose-Re	1984
Prevention of human recombinant interleukin-1 beta (rhIL-1 beta) embryolethality with progesterone or indomethacin. American journal of reproductive immunology (New York, N.Y. : 1989), 1995, Volume: 33, Issue:4 Topics: Adjuvants, Immunologic; Animals; Cytosine; Drug Interactions; Female; Fetal Death; Indomethacin; Int	1995
Prevention of tilorone developmental toxicity with progesterone. Teratology, 1992, Volume: 46, Issue:3 Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Death; Gestational Age; Organ Size; Pregnan	1992

Article

Year

Effects of the interferon inducing agents tilorone and polyriboinosinic acid . polyribocytidylic acid (poly IC) on the hepatic monooxygenase systems of pregnant and fetal rats.

Biochemical pharmacology, 1984, Apr-15, Volume: 33, Issue:8

Topics: Aminopyrine N-Demethylase; Animals; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Dose-Re

1984

Prevention of human recombinant interleukin-1 beta (rhIL-1 beta) embryolethality with progesterone or indomethacin.

American journal of reproductive immunology (New York, N.Y. : 1989), 1995, Volume: 33, Issue:4

Topics: Adjuvants, Immunologic; Animals; Cytosine; Drug Interactions; Female; Fetal Death; Indomethacin; Int

1995

Prevention of tilorone developmental toxicity with progesterone.

Teratology, 1992, Volume: 46, Issue:3

Topics: Animals; Dose-Response Relationship, Drug; Female; Fetal Death; Gestational Age; Organ Size; Pregnan

1992