tilorone has been researched along with Metastase in 3 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inhibition of experimental tumor metastasis was dose-dependent and was observed when animals were treated the day before or the day after tumor-cell injection." | 5.29 | Generation and control of metastasis in experimental tumor systems; inhibition of experimental metastases by a tilorone analogue. ( Algarra, I; Gaforio, JJ; Garrido, F; Höglund, P; Ljunggren, HG; Pérez, M, 1993) |
| "Inhibition of experimental tumor metastasis was dose-dependent and was observed when animals were treated the day before or the day after tumor-cell injection." | 1.29 | Generation and control of metastasis in experimental tumor systems; inhibition of experimental metastases by a tilorone analogue. ( Algarra, I; Gaforio, JJ; Garrido, F; Höglund, P; Ljunggren, HG; Pérez, M, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Basley, WA | 1 |
| Rees, RC | 1 |
| Greager, JA | 1 |
| Baldwin, RW | 1 |
| Algarra, I | 1 |
| Pérez, M | 1 |
| Höglund, P | 1 |
| Gaforio, JJ | 1 |
| Ljunggren, HG | 1 |
| Garrido, F | 1 |
| Zolotareva, GN | 1 |
| Loginova, NS | 1 |
| Galochkina, ZI | 1 |
| Ershov, FI | 1 |
3 other studies available for tilorone and Metastase
| Article | Year |
|---|---|
Antitumour effects of tilorone hydrochloride on the in vivo growth of chemically induced and spontaneously arising rat tumours.
Topics: Adenoma; Animals; Antineoplastic Agents; Fluorenes; Neoplasm Metastasis; Neoplasm Transplantation; N | 1981 |
Generation and control of metastasis in experimental tumor systems; inhibition of experimental metastases by a tilorone analogue.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; G(M1) Gang | 1993 |
[Anticarcinogenic and antimetastatic activity of interferon inducers of natural and synthetic origin with expressed antimutagenic properties].
Topics: Animals; Anticarcinogenic Agents; Antimutagenic Agents; Interferon Inducers; Male; Mice; Mice, Inbre | 1991 |