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tilorone and Lymphopenia

tilorone has been researched along with Lymphopenia in 2 studies

Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.

Lymphopenia: Reduction in the number of lymphocytes.

Research Excerpts

ExcerptRelevanceReference
"Nude athymic mice, which lack T-lymphocytes and are unable to mount a cellular immune response, failed to develop the lymphopenia so characteristically produced by a 100 mg/kg oral dose of tilorone hydrochloride in normal mice."3.65Effect of tilorone hydrochloride on the lymphoid and interferon responses of athymic mice. ( Camyre, KP; Gibson, JP; Megel, H; Michael, JG, 1976)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wildstein, A1
Stevens, LE1
Applebaum, H1
McCabe, RE1
Hashim, GA1
Fitzpatrick, H1
Gibson, JP1
Megel, H1
Camyre, KP1
Michael, JG1

Other Studies

2 other studies available for tilorone and Lymphopenia

ArticleYear
Prolonged survival of canine renal alografts by Tillorone.
    Transplantation, 1976, Volume: 22, Issue:2

    Topics: Animals; Dogs; Fluorenes; Graft Rejection; Kidney Transplantation; Lymphopenia; Male; Tilorone; Time

1976
Effect of tilorone hydrochloride on the lymphoid and interferon responses of athymic mice.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1976, Volume: 151, Issue:2

    Topics: Animals; Fluorenes; Interferons; Lymphopenia; Mice; Mice, Nude; T-Lymphocytes; Tilorone

1976