tilorone has been researched along with Lymphopenia in 2 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
Lymphopenia: Reduction in the number of lymphocytes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nude athymic mice, which lack T-lymphocytes and are unable to mount a cellular immune response, failed to develop the lymphopenia so characteristically produced by a 100 mg/kg oral dose of tilorone hydrochloride in normal mice." | 3.65 | Effect of tilorone hydrochloride on the lymphoid and interferon responses of athymic mice. ( Camyre, KP; Gibson, JP; Megel, H; Michael, JG, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wildstein, A | 1 |
| Stevens, LE | 1 |
| Applebaum, H | 1 |
| McCabe, RE | 1 |
| Hashim, GA | 1 |
| Fitzpatrick, H | 1 |
| Gibson, JP | 1 |
| Megel, H | 1 |
| Camyre, KP | 1 |
| Michael, JG | 1 |
2 other studies available for tilorone and Lymphopenia
| Article | Year |
|---|---|
Prolonged survival of canine renal alografts by Tillorone.
Topics: Animals; Dogs; Fluorenes; Graft Rejection; Kidney Transplantation; Lymphopenia; Male; Tilorone; Time | 1976 |
Effect of tilorone hydrochloride on the lymphoid and interferon responses of athymic mice.
Topics: Animals; Fluorenes; Interferons; Lymphopenia; Mice; Mice, Nude; T-Lymphocytes; Tilorone | 1976 |