tilorone has been researched along with Lung Neoplasms in 4 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
Lung Neoplasms: Tumors or cancer of the LUNG.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Inhibition of experimental tumor metastasis was dose-dependent and was observed when animals were treated the day before or the day after tumor-cell injection." | 5.29 | Generation and control of metastasis in experimental tumor systems; inhibition of experimental metastases by a tilorone analogue. ( Algarra, I; Gaforio, JJ; Garrido, F; Höglund, P; Ljunggren, HG; Pérez, M, 1993) |
| "Inhibition of experimental tumor metastasis was dose-dependent and was observed when animals were treated the day before or the day after tumor-cell injection." | 1.29 | Generation and control of metastasis in experimental tumor systems; inhibition of experimental metastases by a tilorone analogue. ( Algarra, I; Gaforio, JJ; Garrido, F; Höglund, P; Ljunggren, HG; Pérez, M, 1993) |
| "When tilorone was given 7 days after tumor inoculation, it did not show any potentiation of antitumor activity of DFMO." | 1.27 | Potentiation of antitumor and antimetastatic activities of alpha-difluoromethylornithine by interferon inducers. ( Hagan, AC; Lachmann, PJ; Mayer, GD; Prakash, NJ; Rosenberger, AL; Sunkara, PS, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 2 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sunkara, PS | 1 |
| Prakash, NJ | 1 |
| Rosenberger, AL | 1 |
| Hagan, AC | 1 |
| Lachmann, PJ | 1 |
| Mayer, GD | 1 |
| Algarra, I | 2 |
| Pérez, M | 2 |
| Gaforio, JJ | 2 |
| Gasca, F | 1 |
| Garrido, F | 2 |
| Höglund, P | 1 |
| Ljunggren, HG | 1 |
| Palmieri, B | 1 |
| De Martin, G | 1 |
| Noera, G | 1 |
| Aspiro, AM | 1 |
4 other studies available for tilorone and Lung Neoplasms
| Article | Year |
|---|---|
Potentiation of antitumor and antimetastatic activities of alpha-difluoromethylornithine by interferon inducers.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line; Drug Synergism; Eflornithine; Fluorenes; L | 1984 |
In vivo activation of NK cells induces inhibition of lung colonization of H-2 positive and H-2 negative fibrosarcoma tumor clones.
Topics: Animals; Cytotoxicity, Immunologic; Fibrosarcoma; G(M1) Ganglioside; H-2 Antigens; Immune Sera; Kill | 1994 |
Generation and control of metastasis in experimental tumor systems; inhibition of experimental metastases by a tilorone analogue.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; G(M1) Gang | 1993 |
[Immunological surveillance and aspecific immunotherapy in neoplastic diseases].
Topics: Animals; Antibody Formation; Breast Neoplasms; Dogs; Female; Guinea Pigs; Humans; Immunotherapy; Lev | 1976 |