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tilorone and Innate Inflammatory Response

tilorone has been researched along with Innate Inflammatory Response in 1 studies

Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.

Research Excerpts

ExcerptRelevanceReference
"Tilorone (5-35 mg/kg/day) suppressed the development of adjuvant-induced arthritis and the concurrent development of cell-mediated immune response to a secondary immunogen(EL4 cells) in a dose-related manner."7.65Adjuvant polyarthritis. II. Suppression by tilorone. ( Chang, YH, 1977)
"Tilorone (5-35 mg/kg/day) suppressed the development of adjuvant-induced arthritis and the concurrent development of cell-mediated immune response to a secondary immunogen(EL4 cells) in a dose-related manner."3.65Adjuvant polyarthritis. II. Suppression by tilorone. ( Chang, YH, 1977)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Chang, YH1

Other Studies

1 other study available for tilorone and Innate Inflammatory Response

ArticleYear
Adjuvant polyarthritis. II. Suppression by tilorone.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 203, Issue:1

    Topics: Animals; Arthritis; Arthritis, Experimental; Cell Line; Fluorenes; Immunity; Immunity, Cellular; Inf

1977