tilorone has been researched along with Infections, Orthomyxoviridae in 3 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tilorone was administered per os in doses of 40, 150, and 540 μg per mouse 6, 30, and 78 h postinfection, which simulated the drug regimen used in the clinic for the treatment of influenza and acute respiratory viral infections in Russia and post-Soviet countries." | 1.62 | Effect of Tilorone on the Dynamics of Viral Load and the Levels of Interferons and Interleukin-1β in the Lung Tissue and Blood Serum of Mice with Experimental Influenza. ( Chernysheva, AI; Isaeva, EI; Kalyuzhin, OV; Karaulov, AV; Ponezheva, LO; Vetrova, EN, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Kalyuzhin, OV | 1 |
| Isaeva, EI | 1 |
| Vetrova, EN | 1 |
| Chernysheva, AI | 1 |
| Ponezheva, LO | 1 |
| Karaulov, AV | 1 |
| Tazulakhova, EB | 1 |
| Amitina, NN | 1 |
| Ershov, FI | 1 |
| Ikeda, S | 1 |
| Matsuda, Y | 1 |
| Nishimura, C | 1 |
3 other studies available for tilorone and Infections, Orthomyxoviridae
| Article | Year |
|---|---|
Effect of Tilorone on the Dynamics of Viral Load and the Levels of Interferons and Interleukin-1β in the Lung Tissue and Blood Serum of Mice with Experimental Influenza.
Topics: Animals; Antiviral Agents; Drug Administration Schedule; Host-Pathogen Interactions; Influenza A Vir | 2021 |
[Interferon-inducing and antiviral effects of inosiplex in combination with high-molecular interferon inducers].
Topics: Animals; Antiviral Agents; Drug Therapy, Combination; Inosine; Inosine Pranobex; Interferon Inducers | 1985 |
Enhancement by muramyldipeptides of the activities of early-type inducers of interferon.
Topics: Acetylmuramyl-Alanyl-Isoglutamine; Animals; Cell Line; Female; Interferon Inducers; Interferon-gamma | 1985 |