tilorone has been researched along with Herpes Simplex Virus Infection in 5 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Two models, hamster and rabbit cornea, were selected for assays of protection afforded by tilorone dihydrochloride against herpes simplex (HSV) and vesicular stomatitis viruses (VSV)." | 7.65 | The mode of inhibition of herpes simplex and vesicular stomatitis ocular viral infections in the rabbit and hamster by an interferon inducer tilorone dihydrochloride. ( Tokumaru, T, 1975) |
| "A mouse model of encephalitis caused by herpes simplex virus was used to compare the antiviral activity of tilorone hydrochloride with that of phosphonoacetic acid." | 7.65 | Experimental encephalitis caused by herpes simplex virus: comparison of treatment with tilorone hydrochloride and phosphonoacetic acid. ( Fitzwilliam, JF; Griffith, JF, 1976) |
| " Two models, hamster and rabbit cornea, were selected for assays of protection afforded by tilorone dihydrochloride against herpes simplex (HSV) and vesicular stomatitis viruses (VSV)." | 3.65 | The mode of inhibition of herpes simplex and vesicular stomatitis ocular viral infections in the rabbit and hamster by an interferon inducer tilorone dihydrochloride. ( Tokumaru, T, 1975) |
| "A mouse model of encephalitis caused by herpes simplex virus was used to compare the antiviral activity of tilorone hydrochloride with that of phosphonoacetic acid." | 3.65 | Experimental encephalitis caused by herpes simplex virus: comparison of treatment with tilorone hydrochloride and phosphonoacetic acid. ( Fitzwilliam, JF; Griffith, JF, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (80.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bogorad-Kobel's'ka, OS | 1 |
| Zholobak, NM | 1 |
| Olevins'ka, ZM | 1 |
| Spivak, MIa | 1 |
| Pollard, RB | 1 |
| De Clercq, E | 1 |
| Descamps, J | 1 |
| Verhelst, G | 1 |
| Walker, RT | 1 |
| Jones, AS | 1 |
| Torrence, PF | 1 |
| Shugar, D | 1 |
| Tokumaru, T | 1 |
| Fitzwilliam, JF | 1 |
| Griffith, JF | 1 |
5 other studies available for tilorone and Herpes Simplex Virus Infection
| Article | Year |
|---|---|
[The antiviral activity of diphenyl derivatives in different model systems].
Topics: Animals; Antiviral Agents; Biphenyl Compounds; Cell Line; Cytopathogenic Effect, Viral; Fibroblasts; | 2012 |
Usages of interferon and interferon inducers in man: the second half of 1980.
Topics: Hepatitis B; Herpes Simplex; Herpesviridae Infections; Herpesvirus 4, Human; Humans; Interferon Indu | 1981 |
Comparative efficacy of antiherpes drugs against different strains of herpes simplex virus.
Topics: Antiviral Agents; Cytarabine; Herpes Simplex; Mutation; Simplexvirus; Thymidine Kinase; Tilorone; Va | 1980 |
The mode of inhibition of herpes simplex and vesicular stomatitis ocular viral infections in the rabbit and hamster by an interferon inducer tilorone dihydrochloride.
Topics: Animals; Cornea; Cricetinae; Fluorenes; Herpes Simplex; Male; Rabbits; Stomatitis; Tilorone; Time Fa | 1975 |
Experimental encephalitis caused by herpes simplex virus: comparison of treatment with tilorone hydrochloride and phosphonoacetic acid.
Topics: Acetates; Animals; Animals, Newborn; Antiviral Agents; Disease Models, Animal; Drug Therapy, Combina | 1976 |