tilorone has been researched along with Delayed Hypersensitivity in 4 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of tilorone, which is known to suppress adjuvant arthritis, on the induction of collagen arthritis in rats was investigated." | 7.67 | Enhancing effects of tilorone on collagen arthritis and humoral immune response to type II collagen. ( Arai, K; Arita, C; Hotokebuchi, T; Kaibara, N; Morinaga, M; Takagishi, K, 1987) |
| "The effect of tilorone, which is known to suppress adjuvant arthritis, on the induction of collagen arthritis in rats was investigated." | 3.67 | Enhancing effects of tilorone on collagen arthritis and humoral immune response to type II collagen. ( Arai, K; Arita, C; Hotokebuchi, T; Kaibara, N; Morinaga, M; Takagishi, K, 1987) |
| "The chronic administration of Tilorone [(2,7-bis(diethylamino)ethoxy]fluoren-9-one) with antigen seems to prevent the generation of DTH effector cells." | 1.26 | Modulation of the acquisition and expression of immunity by Tilorone: I. Delayed-type hypersensitivity responses. ( Kettman, JR, 1978) |
| "Tilorone treatment at the 100-mg/kg dose level increased the growth of S." | 1.25 | Effect of tilorone treatment on intracellular microbial infections in specific-pathogen-free mice. ( Collins, FM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aiuti, F | 1 |
| Montella, F | 1 |
| Kettman, JR | 1 |
| Collins, FM | 1 |
| Kaibara, N | 1 |
| Takagishi, K | 1 |
| Hotokebuchi, T | 1 |
| Morinaga, M | 1 |
| Arita, C | 1 |
| Arai, K | 1 |
4 other studies available for tilorone and Delayed Hypersensitivity
| Article | Year |
|---|---|
[Concepts of stimulating immunotherapy].
Topics: Adjuvants, Immunologic; Antiviral Agents; Ascorbic Acid; Bacterial Infections; Glucans; Humans; Hype | 1982 |
Modulation of the acquisition and expression of immunity by Tilorone: I. Delayed-type hypersensitivity responses.
Topics: Animals; Antigens; Hypersensitivity, Delayed; Injections, Intravenous; Leukocytes; Mice; Mice, Inbre | 1978 |
Effect of tilorone treatment on intracellular microbial infections in specific-pathogen-free mice.
Topics: Animals; Bacterial Infections; Female; Fluorenes; Hypersensitivity, Delayed; Immunity, Cellular; Mic | 1975 |
Enhancing effects of tilorone on collagen arthritis and humoral immune response to type II collagen.
Topics: Animals; Antibody Formation; Arthritis; Arthritis, Experimental; Collagen; Female; Fluorenes; Hypers | 1987 |