tilorone has been researched along with Corneal Opacity in 2 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
Corneal Opacity: Disorder occurring in the central or peripheral area of the cornea. The usual degree of transparency becomes relatively opaque.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tilorone was applied either orally (60-90 mg/kg) for several weeks or topically (2%) for a few days." | 1.27 | Keratopathy in rats after treatment with tilorone. ( Lüllmann-Rauch, R, 1986) |
| "Retrospective study of 14 cancer patients who were taking tilorone HCl orally revealed that three patients had similar ophthalmic findings accompanied by the appearance of blue halos around pinpoint light sources." | 1.26 | Keratopathy after oral administration of tilorone hydrochloride. ( Regelson, W; Weinberg, RS; Weiss, JN, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weiss, JN | 1 |
| Weinberg, RS | 1 |
| Regelson, W | 1 |
| Lüllmann-Rauch, R | 1 |
2 other studies available for tilorone and Corneal Opacity
| Article | Year |
|---|---|
Keratopathy after oral administration of tilorone hydrochloride.
Topics: Adult; Conjunctiva; Cornea; Corneal Opacity; Endothelium; Female; Fluorenes; Humans; Inclusion Bodie | 1980 |
Keratopathy in rats after treatment with tilorone.
Topics: Animals; Corneal Opacity; Female; Fluorenes; Rats; Rats, Inbred Strains; Tilorone | 1986 |