Page last updated: 2024-11-05

tilorone and Chagas Disease

tilorone has been researched along with Chagas Disease in 1 studies

Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.

Chagas Disease: Infection with the protozoan parasite TRYPANOSOMA CRUZI, a form of TRYPANOSOMIASIS endemic in Central and South America. It is named after the Brazilian physician Carlos Chagas, who discovered the parasite. Infection by the parasite (positive serologic result only) is distinguished from the clinical manifestations that develop years later, such as destruction of PARASYMPATHETIC GANGLIA; CHAGAS CARDIOMYOPATHY; and dysfunction of the ESOPHAGUS or COLON.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
James, SL1
Kipnis, TL1
Sher, A1
Hoff, R1

Other Studies

1 other study available for tilorone and Chagas Disease

ArticleYear
Enhanced resistance to acute infection with Trypanosoma cruzi in mice treated with an interferon inducer.
    Infection and immunity, 1982, Volume: 35, Issue:2

    Topics: Animals; Chagas Disease; Female; Fluorenes; Immunity; Interferons; Killer Cells, Natural; Macrophage

1982