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tilorone and Cell Transformation, Neoplastic

tilorone has been researched along with Cell Transformation, Neoplastic in 2 studies

Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.

Cell Transformation, Neoplastic: Cell changes manifested by escape from control mechanisms, increased growth potential, alterations in the cell surface, karyotypic abnormalities, morphological and biochemical deviations from the norm, and other attributes conferring the ability to invade, metastasize, and kill.

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Green, M1
Rankin, A1
Gerard, GF1
Grandgenett, DP1
Green, MR1
Benedict, WF1
Banerjee, A1
Gardner, A1
Jones, PA1

Other Studies

2 other studies available for tilorone and Cell Transformation, Neoplastic

ArticleYear
Inhibition of purified DNA polymerase of RNA tumor viruses by fluoranthene derivatives and analogues of tilorone hydrochloride.
    Journal of the National Cancer Institute, 1975, Volume: 55, Issue:2

    Topics: Anthraquinones; Avian Leukosis Virus; Avian Myeloblastosis Virus; Binding Sites; Cell Transformation

1975
Induction of morphological transformation in mouse C3H/10T1/2 clone 8 cells and chromosomal damage in hamster A(T1)C1-3 cells by cancer chemotherapeutic agents.
    Cancer research, 1977, Volume: 37, Issue:7 Pt 1

    Topics: Antineoplastic Agents; Bleomycin; Carcinogens; Cell Transformation, Neoplastic; Cells, Cultured; Chr

1977