tilorone has been researched along with Bacterial Disease in 3 studies
Tilorone: An antiviral agent used as its hydrochloride. It is the first recognized synthetic, low-molecular-weight compound that is an orally active interferon inducer, and is also reported to have antineoplastic and anti-inflammatory actions.
tilorone : A member of the class of fluoren-9-ones that is 9H-fluoren-9-one which is substituted by a 2-(diethylamino)ethoxy group at positions 2 and 7. It is an interferon inducer and a selective alpha7 nicotinic acetylcholine receptor (alpha7 nAChR) agonist. Its hydrochloride salt is used as an antiviral drug.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Tilorone treatment reduced the granulomatous response within the Salmonella-infected liver, suggesting that the drug interferes with the mobilization of the mononuclear defenses within the normal host." | 1.26 | Mechanism of cellular suppression induced by oral tilorone treatment of mice. ( Collins, FM, 1980) |
| "Tilorone treatment at the 100-mg/kg dose level increased the growth of S." | 1.25 | Effect of tilorone treatment on intracellular microbial infections in specific-pathogen-free mice. ( Collins, FM, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aiuti, F | 1 |
| Montella, F | 1 |
| Collins, FM | 2 |
3 other studies available for tilorone and Bacterial Disease
| Article | Year |
|---|---|
[Concepts of stimulating immunotherapy].
Topics: Adjuvants, Immunologic; Antiviral Agents; Ascorbic Acid; Bacterial Infections; Glucans; Humans; Hype | 1982 |
Mechanism of cellular suppression induced by oral tilorone treatment of mice.
Topics: Animals; Bacterial Infections; Fluorenes; Hypersensitivity, Immediate; Immune Tolerance; Immunity, C | 1980 |
Effect of tilorone treatment on intracellular microbial infections in specific-pathogen-free mice.
Topics: Animals; Bacterial Infections; Female; Fluorenes; Hypersensitivity, Delayed; Immunity, Cellular; Mic | 1975 |