tiletamine hydrochloride has been researched along with Liver Neoplasms in 41 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.88) | 18.2507 |
| 2000's | 15 (36.59) | 29.6817 |
| 2010's | 20 (48.78) | 24.3611 |
| 2020's | 4 (9.76) | 2.80 |
| Authors | Studies |
|---|---|
| Aktuglu Zeybek, AC; Cansever, MS; Erel, O; Iscan, HZ; Kiykim, E; Neselioglu, S; Zubarioglu, T | 1 |
| Balouch, F; Bhushan, S; Ee, L; Hodgkinson, P; Lampe, G; Lewindon, P; McGill, J; Noble, C | 1 |
| Almuqbil, M; Chinsky, JM; Knoll, J | 1 |
| Hakeem, A; Jalan, A; Menon, J; Reddy, MS; Rela, M; Shanmugam, N; Valamparampil, JJ; Vij, M | 1 |
| Pennings, JP; van Ginkel, WG; van Spronsen, FJ | 1 |
| Mitchell, GA; Yang, H | 1 |
| Cao, Y; Duan, JA; Oberer, L; Zhao, M; Zhu, Y; Zhu, ZH | 1 |
| Chiang, BH; Li, TY | 1 |
| Aydogdu, S; Farajov, R; Iakobadze, Z; Karaca, CA; Kilic, M; Yilmaz, C | 1 |
| Janovszky, A; Karg, E; László, A; Rózsa, M; Sallay, E; Tiszlavicz, L; Túri, S; Ugarte, M; Várkonyi, A; Wittmann, G | 1 |
| Chapchap, P; Feier, FH; Fonseca, EA; Leite, KM; Miura, IK; Porta, A; Porta, G; Pugliese, R; Seda Neto, J | 1 |
| Chang, CH; Chang, WL; Chung, CH; Hsu, CC; Huang, TF; Ko, FN; Lin, KT; Peng, HC; Wang, SW | 1 |
| Cervello, M; Cusimano, A; D'Alessandro, N; Loria, GR; McCubrey, JA; Montalto, G; Puleio, R | 1 |
| Chien, CW; Dinkova-Kostova, AT; Higgins, M; Honda, T; Li, W; Mendis, AT; Mierke, DF; Morra, RP; Ojima, I; Zheng, S | 1 |
| Chang, Y; Huang, JP; Jin, Z; Ju, HX; Wang, HM; Wang, WF | 1 |
| Finegold, M; Grompe, M; Lee, AY; Rothfuss, A; Sharma, AD; Vogel, A; Wang, Z; Willenbring, H | 1 |
| Buitrago-Molina, LE; Cañón, JM; Finegold, M; Geffers, R; Grompe, M; Lamlé, J; Manns, MP; Marhenke, S; Sporn, M; Vogel, A; Yamamoto, M | 1 |
| Azzolina, A; Cervello, M; D'Alessandro, N; Lampiasi, N; McCubrey, JA; Montalto, G; Umezawa, K | 1 |
| Barak, V; Chowers, I; Dror, R; Lederman, M; Pe'er, J; Umezawa, K | 1 |
| Callea, F; Castellano, A; Dionisi-Vici, C; Francalanci, P; Holme, E; Jenkner, A; Nobili, V | 1 |
| Chiang, BH; Kuo, YH; Lin, YW; Liu, RH; Pan, JH; Sheen, LY | 1 |
| Al-Din, ES; El-Sabbagh, OI; Kadry, HH; Shabaan, MA | 1 |
| Liu, H; Ruan, J; Wei, A; Xiao, Y; Xiong, C | 1 |
| Azzolina, A; Cervello, M; Lampiasi, N; McCubrey, JA; Montalto, G; Umezawa, K | 1 |
| Arias, C; Cabello, JF; Castro, G; Cornejo, V; de la Parra, A; Fernández, E; Raimann, E | 1 |
| Czech, B; Dorn, C; Gehrig, M; Heilmann, J; Hellerbrand, C; Saugspier, M | 1 |
| Aiura, K; Itano, O; Kitagawa, Y; Matsuda, S; Suzuki, K; Takeuchi, O; Umezawa, K | 1 |
| Bijleveld, CM; van Maldegem, BT; van Spronsen, FJ; Wijburg, FA | 1 |
| Alaimo, A; Carina, V; Cervello, M; Cusimano, A; D'Alessandro, N; Labbozzetta, M; Maurici, A; Notarbartolo, M; Poma, P; Sanguedolce, R | 1 |
| McKiernan, PJ | 1 |
| Eguchi, K; Fukuta, M; Goto, T; Hamasaki, K; Ichikawa, T; Ishikawa, H; Kawashimo, H; Matsumoto, K; Motoyoshi, Y; Nakao, K; Nishimura, D; Shibata, H; Taura, N; Umezawa, K | 1 |
| Bijleveld, CM; Koelink, CJ; van den Heuvel-Eibrink, MM; van der Ploeg, A; van Hasselt, P; van Spronsen, FJ; Wijburg, FA | 1 |
| Cervello, M; D'Alessandro, N; Giannitrapani, L; Labbozzetta, M; Montalto, G; Notarbartolo, M; Poma, P | 1 |
| Bergeron, A; Finegold, MJ; Jorquera, R; Langlois, C; Orejuela, D; Rhead, WJ; Tanguay, RM | 1 |
| Bergeron, A; Finegold, MJ; Jorquera, R; Orejuela, D; Tanguay, RM | 1 |
| Baumann, U; Santra, S | 1 |
| al-Dhalimy, M; Finegold, M; Grompe, M; Kennaway, NG; Lindstedt, S; Ou, CN; Papaconstantinou, J; Torres-Ramos, CA | 1 |
| Al-Dhalimy, M; Brantly, M; Finegold, M; Grompe, M; Ou, CN; Overturf, K; Tanguay, R | 1 |
| Holme, E; Lindstedt, S | 1 |
| Bozak, RE; Dinkova-Kostova, AT; Hicks, RJ; Massiah, MA; Talalay, P | 1 |
| González Pascual, E; Holme, E; Lambruschini Ferri, N; Mas Comas, A; Ros Viladoms, J; Vilaseca Buscà, MA | 1 |
4 review(s) available for tiletamine hydrochloride and Liver Neoplasms
| Article | Year |
|---|---|
Liver Cancer in Tyrosinemia Type 1.
Topics: Biomarkers, Tumor; Carcinoma, Hepatocellular; Cyclohexanones; Early Detection of Cancer; Humans; Liver Neoplasms; Nitrobenzoates; Tyrosinemias | 2017 |
Remaining Challenges in the Treatment of Tyrosinemia from the Clinician's Viewpoint.
Topics: Animals; Cyclohexanones; Diet; Diet Therapy; Humans; Infant, Newborn; Kidney Diseases; Liver Failure; Liver Neoplasms; Liver Transplantation; Neonatal Screening; Nitrobenzoates; Tyrosinemias | 2017 |
Experience of nitisinone for the pharmacological treatment of hereditary tyrosinaemia type 1.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Carcinoma, Hepatocellular; Child; Cyclohexanones; Enzyme Inhibitors; Humans; Liver Diseases; Liver Neoplasms; Monitoring, Physiologic; Nitrobenzoates; Tyrosinemias | 2008 |
Nontransplant treatment of tyrosinemia.
Topics: Age Factors; Animals; Carcinoma, Hepatocellular; Child, Preschool; Cyclohexanones; Enzyme Inhibitors; Humans; Infant; Liver Neoplasms; Nitrobenzoates; Risk Factors; Tyrosinemias | 2000 |
37 other study(ies) available for tiletamine hydrochloride and Liver Neoplasms
| Article | Year |
|---|---|
Evaluation of dynamic thiol/disulfide homeostasis in hereditary tyrosinemia type 1 patients.
Topics: Carcinoma, Hepatocellular; Cyclohexanones; Disulfides; Homeostasis; Humans; Liver Neoplasms; Nitrobenzoates; Oxidative Stress; Sulfhydryl Compounds; Tyrosine; Tyrosinemias | 2022 |
Hepatocellular carcinoma requiring liver transplantation in hereditary tyrosinemia type 1 despite nitisinone therapy and α1-fetoprotein normalization.
Topics: alpha-Fetoproteins; Carcinoma, Hepatocellular; Child; Cyclohexanones; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Liver Transplantation; Nitrobenzoates; Tyrosinemias | 2022 |
Late Development of Hepatocellular Carcinoma in Tyrosinemia Type 1 Despite Nitisinone (NTBC) Treatment.
Topics: Carcinoma, Hepatocellular; Cyclohexanones; Enzyme Inhibitors; Humans; Liver Neoplasms; Nitrobenzoates; Tyrosinemias | 2020 |
Liver Transplantation: A Safe and Definitive Alternative to Lifelong Nitisinone for Tyrosinemia Type 1.
Topics: Carcinoma, Hepatocellular; Child; Cyclohexanones; Humans; Liver Neoplasms; Liver Transplantation; Nitrobenzoates; Retrospective Studies; Treatment Outcome; Tyrosinemias | 2022 |
Diselaginellin B, an Unusual Dimeric Molecule from Selaginella pulvinata, Inhibited Metastasis and Induced Apoptosis of SMMC-7721 Human Hepatocellular Carcinoma Cells.
Topics: Antineoplastic Agents, Phytogenic; Apoptosis; Biphenyl Compounds; Carcinoma, Hepatocellular; Cell Line, Tumor; Cyclohexanones; Down-Regulation; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Neoplasm Metastasis; Plant Extracts; Selaginellaceae; Up-Regulation | 2017 |
4-Acetylantroquinonol B from antrodia cinnamomea enhances immune function of dendritic cells against liver cancer stem cells.
Topics: 4-Butyrolactone; Animals; Antrodia; Cell Survival; Coculture Techniques; Cyclohexanones; Dendritic Cells; Dose-Response Relationship, Drug; Hep G2 Cells; Humans; Immunity, Cellular; Liver Neoplasms; Mice; Neoplastic Stem Cells; RAW 264.7 Cells | 2019 |
Live donor liver transplantation for type 1 tyrosinemia: An analysis of 15 patients.
Topics: Adolescent; Adult; Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclohexanones; Databases, Factual; Female; Humans; Infant; Infant, Newborn; Liver Neoplasms; Liver Transplantation; Living Donors; Male; Neonatal Screening; Nitrobenzoates; Retrospective Studies; Treatment Outcome; Tyrosinemias | 2019 |
The fate of tyrosinaemic Hungarian patients before the NTBC aera.
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Carcinoma, Hepatocellular; Carcinoma, Renal Cell; Child, Preschool; Cyclohexanones; Enzyme Inhibitors; Fatal Outcome; Homozygote; Humans; Hungary; Hydrolases; Kidney Neoplasms; Liver Neoplasms; Male; Nitrobenzoates; Treatment Outcome; Tyrosine; Tyrosinemias | 2013 |
HCC prevalence and histopathological findings in liver explants of patients with hereditary tyrosinemia type 1.
Topics: Carcinoma, Hepatocellular; Child; Child, Preschool; Cyclohexanones; Drug Resistance; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Infant; Liver; Liver Neoplasms; Liver Transplantation; Male; Nitrobenzoates; Prognosis; Retrospective Studies; Tomography, X-Ray Computed; Tyrosinemias | 2014 |
4-Acetylantroquinonol B suppresses tumor growth and metastasis of hepatoma cells via blockade of translation-dependent signaling pathway and VEGF production.
Topics: 4-Butyrolactone; Animals; Antineoplastic Agents; Antrodia; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Cyclohexanones; Down-Regulation; Hep G2 Cells; Humans; Liver Neoplasms; Male; Metatarsal Bones; Mice, Nude; Mice, SCID; Phosphorylation; Protein Biosynthesis; Signal Transduction; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2015 |
Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cells.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Proliferation; Cyclohexanones; Humans; Liver Neoplasms; Male; Mice; Mice, Nude; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Xenograft Model Antitumor Assays | 2015 |
New Monocyclic, Bicyclic, and Tricyclic Ethynylcyanodienones as Activators of the Keap1/Nrf2/ARE Pathway and Inhibitors of Inducible Nitric Oxide Synthase.
Topics: Adaptor Proteins, Signal Transducing; Alkynes; Animals; Anti-Inflammatory Agents; Antineoplastic Agents; Carboxylic Ester Hydrolases; Carcinoma, Hepatocellular; Cell Proliferation; Cells, Cultured; Cyclohexanones; Cytoskeletal Proteins; Inflammation; Kelch-Like ECH-Associated Protein 1; Lipopolysaccharides; Liver Neoplasms; Macrophages; Mice; Models, Molecular; Molecular Structure; NF-E2-Related Factor 2; Nitric Oxide Synthase Type II; Signal Transduction; Structure-Activity Relationship | 2015 |
Dryocrassin ABBA Induces Apoptosis in Human Hepatocellular Carcinoma HepG2 Cells Through a Caspase-Dependent Mitochondrial Pathway.
Topics: Animals; Apoptosis; Benzylidene Compounds; Blotting, Western; Carcinoma, Hepatocellular; Caspases; Cell Proliferation; Cyclohexanones; Humans; Liver Neoplasms; Male; Membrane Potential, Mitochondrial; Mice; Mitochondria; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Signal Transduction; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2016 |
Loss of p21 permits carcinogenesis from chronically damaged liver and kidney epithelial cells despite unchecked apoptosis.
Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Hepatectomy; Hepatocytes; Hydrolases; Kidney Diseases, Cystic; Kidney Neoplasms; Kidney Tubules, Proximal; Liver Neoplasms; Liver Regeneration; Mice; Mice, Knockout; Neoplasms; Nitrobenzoates; Tyrosinemias | 2008 |
Activation of nuclear factor E2-related factor 2 in hereditary tyrosinemia type 1 and its role in survival and tumor development.
Topics: Animals; Cyclohexanones; DNA Damage; Dose-Response Relationship, Drug; Glutathione; Hepatitis; Hydrolases; Imidazoles; Inactivation, Metabolic; Liver; Liver Cirrhosis; Liver Failure; Liver Neoplasms; Mice; Mice, Knockout; NF-E2-Related Factor 2; Nitrobenzoates; Oleanolic Acid; Oxidative Stress; Tyrosinemias | 2008 |
Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism.
Topics: Antineoplastic Agents; Apoptosis; Benzamides; Carcinoma, Hepatocellular; Caspases; Cell Line, Tumor; Cell Proliferation; Cyclohexanones; Cytochromes c; Dose-Response Relationship, Drug; Down-Regulation; Drug Evaluation, Preclinical; Endoplasmic Reticulum Chaperone BiP; Enzyme Activation; Humans; Liver Neoplasms; Mitogen-Activated Protein Kinases; NF-kappa B; Poly(ADP-ribose) Polymerases; Reactive Oxygen Species | 2009 |
Characterizing the involvement of the nuclear factor-kappa B (NF kappa B) transcription factor in uveal melanoma.
Topics: Apoptosis; Benzamides; Blotting, Western; Caspase 3; Cell Proliferation; Cyclohexanones; Fluorescent Antibody Technique, Indirect; Humans; Imidazoles; Ki-67 Antigen; Liver Neoplasms; Melanoma; NF-kappa B; Quinoxalines; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured; Uveal Neoplasms | 2010 |
Tyrosinemia type 1: metastatic hepatoblastoma with a favorable outcome.
Topics: Adolescent; Biopsy, Needle; Carcinoma, Hepatocellular; Chemotherapy, Adjuvant; Cyclohexanones; Diagnosis, Differential; Female; Follow-Up Studies; Hepatectomy; Hepatoblastoma; Humans; Immunohistochemistry; Liver Neoplasms; Nitrobenzoates; Risk Assessment; Treatment Outcome; Tyrosinemias | 2010 |
The 4-acetylantroquinonol B isolated from mycelium of Antrodia cinnamomea inhibits proliferation of hepatoma cells.
Topics: 4-Butyrolactone; Antineoplastic Agents; Antrodia; Biological Products; Carcinoma, Hepatocellular; Cell Proliferation; Cyclohexanones; Fermentation; Hep G2 Cells; Humans; Liver Neoplasms; Mycelium | 2010 |
Synthesis of new nonclassical acridines, quinolines, and quinazolines derived from dimedone for biological evaluation.
Topics: Acridines; Anti-Bacterial Agents; Antineoplastic Agents; Cyclohexanones; Gram-Negative Bacteria; Gram-Positive Bacteria; Hep G2 Cells; Humans; Inhibitory Concentration 50; Liver Neoplasms; Microbial Sensitivity Tests; Quinazolines; Quinolines | 2010 |
Apoptosis induced by a new flavonoid in human hepatoma HepG2 cells involves reactive oxygen species-mediated mitochondrial dysfunction and MAPK activation.
Topics: Acetylcysteine; Anthracenes; Apoptosis; Carcinoma, Hepatocellular; Caspases; Cell Survival; Cyclohexanones; Enzyme Activation; Flavones; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Imidazoles; Intracellular Space; JNK Mitogen-Activated Protein Kinases; Liver Neoplasms; MAP Kinase Signaling System; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinases; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Pyridines; Reactive Oxygen Species | 2011 |
The novel NF-κB inhibitor DHMEQ synergizes with celecoxib to exert antitumor effects on human liver cancer cells by a ROS-dependent mechanism.
Topics: Acetylcysteine; Antineoplastic Agents; Apoptosis; Benzamides; Carcinoma, Hepatocellular; Celecoxib; Cell Cycle Proteins; Cell Line, Tumor; Cell Proliferation; Cyclohexanones; Cyclooxygenase 2 Inhibitors; Drug Synergism; Endoplasmic Reticulum Stress; fas Receptor; Humans; Liver Neoplasms; NF-kappa B; Poly(ADP-ribose) Polymerases; Protein Serine-Threonine Kinases; Pyrazoles; Reactive Oxygen Species; Repressor Proteins; Sulfonamides | 2012 |
[Clinical follow up of Chilean patients with tyrosinemia type 1 treated with 2-(2-nitro-4-trifluoromethylbenzoyl)-1,3-ciclohexanedione (NTBC)].
Topics: Child, Preschool; Chile; Cyclohexanones; Enzyme Inhibitors; Female; Follow-Up Studies; Humans; Infant; Liver Neoplasms; Liver Transplantation; Male; Nitrobenzoates; Retrospective Studies; Time Factors; Treatment Outcome; Tyrosinemias | 2012 |
Hop bitter acids inhibit tumorigenicity of hepatocellular carcinoma cells in vitro.
Topics: Acids; Antineoplastic Agents, Phytogenic; Aspartate Aminotransferases; Carcinoma, Hepatocellular; Cell Movement; Cell Proliferation; Cyclohexanones; Cyclohexenes; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Humulus; Liver Neoplasms; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; NF-kappa B; Phosphorylation; Plant Extracts; Terpenes; Transcription Factor AP-1; Tumor Cells, Cultured | 2012 |
Combined effect of dehydroxymethylepoxyquinomicin and gemcitabine in a mouse model of liver metastasis of pancreatic cancer.
Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Blotting, Western; Cell Movement; Cell Proliferation; Cyclohexanones; Deoxycytidine; Disease Models, Animal; Fluorescent Antibody Technique; Gemcitabine; Humans; Immunoenzyme Techniques; Interleukin-8; Liver Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured | 2013 |
Hepatocellular carcinoma in hereditary tyrosinemia type I despite 2-(2 nitro-4-3 trifluoro- methylbenzoyl)-1, 3-cyclohexanedione treatment.
Topics: Carcinoma, Hepatocellular; Child, Preschool; Cyclohexanones; Enzyme Inhibitors; Humans; Liver Neoplasms; Liver Transplantation; Male; Nitrobenzoates; Treatment Outcome; Tyrosinemias | 2005 |
Antitumor effects of the novel NF-kappaB inhibitor dehydroxymethyl-epoxyquinomicin on human hepatic cancer cells: analysis of synergy with cisplatin and of possible correlation with inhibition of pro-survival genes and IL-6 production.
Topics: Antineoplastic Agents; bcl-X Protein; Benzamides; Carcinoma, Hepatocellular; Cell Line, Tumor; Cell Nucleus; Cell Survival; Cisplatin; Cyclohexanones; Dose-Response Relationship, Drug; Drug Synergism; Gene Expression; HeLa Cells; Humans; Inhibitor of Apoptosis Proteins; Interleukin-6; Liver Neoplasms; Neuronal Apoptosis-Inhibitory Protein; NF-kappa B; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Time Factors | 2006 |
Nitisinone in the treatment of hereditary tyrosinaemia type 1.
Topics: Carcinoma, Hepatocellular; Cyclohexanones; Enzyme Inhibitors; Humans; Kidney Diseases; Liver Diseases; Liver Failure; Liver Neoplasms; Liver Transplantation; Monitoring, Physiologic; Nitrobenzoates; Tyrosine; Tyrosinemias | 2006 |
DHMEQ, a novel NF-kappaB inhibitor, induces apoptosis and cell-cycle arrest in human hepatoma cells.
Topics: Animals; Apoptosis; bcl-X Protein; Benzamides; Blotting, Western; Carcinoma, Hepatocellular; Cell Cycle; Cyclohexanones; Electrophoretic Mobility Shift Assay; Humans; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Protein Transport; Proto-Oncogene Proteins c-bcl-2; Tumor Necrosis Factor-alpha | 2006 |
Tyrosinemia type I treated by NTBC: how does AFP predict liver cancer?
Topics: alpha-Fetoproteins; Child; Child, Preschool; Cyclohexanones; Enzyme Inhibitors; Female; Humans; Infant; Liver Neoplasms; Male; Nitrobenzoates; Prognosis; Tyrosinemias | 2006 |
Significance of autologous interleukin-6 production in the HA22T/VGH cell model of hepatocellular carcinoma.
Topics: Antibodies; Benzamides; Carcinoma, Hepatocellular; Cell Membrane; Curcumin; Cyclohexanones; Cytokine Receptor gp130; Humans; Interleukin-6; Liver Neoplasms; Models, Biological; NF-kappa B; Receptors, Interleukin-6; RNA, Small Interfering; Tumor Cells, Cultured | 2006 |
Rescue from neonatal death in the murine model of hereditary tyrosinemia by glutathione monoethylester and vitamin C treatment.
Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Cyclohexanones; Disease Models, Animal; Drug Therapy, Combination; Female; Glutathione; Hydrolases; Liver Neoplasms; Mice; Mice, Knockout; Nitrobenzoates; Oxidative Stress; Pregnancy; Tyrosinemias | 2008 |
Hepatic stress in hereditary tyrosinemia type 1 (HT1) activates the AKT survival pathway in the fah-/- knockout mice model.
Topics: Animals; bcl-X Protein; Carcinoma, Hepatocellular; Cyclohexanones; Disease Models, Animal; Hydrolases; Liver Neoplasms; Mice; Mice, Knockout; Nitrobenzoates; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tyrosinemias | 2008 |
Pharmacological correction of neonatal lethal hepatic dysfunction in a murine model of hereditary tyrosinaemia type I.
Topics: alpha-Fetoproteins; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Female; Heptanoates; Humans; Hydrolases; Liver; Liver Diseases; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Nitrobenzoates; Pancreas; RNA, Messenger; Tyrosine | 1995 |
Hepatocytes corrected by gene therapy are selected in vivo in a murine model of hereditary tyrosinaemia type I.
Topics: Amino Acid Metabolism, Inborn Errors; Animals; Cell Count; Cell Transplantation; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Genetic Therapy; Humans; Hydrolases; Immunoenzyme Techniques; Liver; Liver Function Tests; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Nitrobenzoates; Retroviridae; Tyrosine | 1996 |
Potency of Michael reaction acceptors as inducers of enzymes that protect against carcinogenesis depends on their reactivity with sulfhydryl groups.
Topics: Animals; Benzylidene Compounds; Butanones; Carcinoma, Hepatocellular; Chalcone; Cinnamates; Coumarins; Cyclohexanones; Cyclopentanes; Enzyme Induction; FMN Reductase; Glutathione; Glutathione Transferase; Humans; Liver Neoplasms; Magnetic Resonance Spectroscopy; Mice; Molecular Structure; NADH, NADPH Oxidoreductases; Sulfhydryl Compounds; Tumor Cells, Cultured | 2001 |
[Evolution of a case of tyrosinemia type I treated with NTBC].
Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Adolescent; Carcinoma, Hepatocellular; Cyclohexanones; Enzyme Inhibitors; Humans; Liver Neoplasms; Male; Nitrobenzoates; Palliative Care; Tyrosinemias | 2001 |