tiletamine hydrochloride and Disease Models, Animal

Topics: Animals; Anti-Inflammatory Agents; Benzamides; Cyclohexanones; Disease Models, Animal; Humans; Inflammation; Mice; NF-kappa B

Topics: Alkaptonuria; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Homogentisic Acid; Humans; Mice; Nitrobenzoates; Tyrosine

Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Amino Acid Metabolism, Inborn Errors; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Genetic Therapy; Humans; Liver Transplantation; Nitrobenzoates; Phenotype; Tyrosine

Topics: Animals; Anti-Inflammatory Agents; Apoptosis; Benzylidene Compounds; Cardiomyopathies; Cell Line; Cyclohexanones; Cytokines; Diet, High-Fat; Disease Models, Animal; JNK Mitogen-Activated Protein Kinases; Male; Mice, Inbred C57BL; Myocarditis; Myocytes, Cardiac; NF-kappa B; Obesity; Palmitic Acid; Rats; Signal Transduction

Topics: Animals; Apoptosis; beta Catenin; Biomarkers; Cell Cycle; Cell Line, Tumor; Cells, Cultured; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Epithelial-Mesenchymal Transition; Humans; Mice; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyridines; Signal Transduction; Urinary Bladder Neoplasms

Topics: Administration, Intravenous; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Cycle; Cell Line, Tumor; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Humans; Mice; Molecular Structure; Polymers; Protein Kinase Inhibitors; Xenograft Model Antitumor Assays

Topics: Animals; Anti-Inflammatory Agents; Carrageenan; Cyclohexanones; Disease Models, Animal; Edema; Epimedium; Gene Expression Regulation; Glucosides; Lipopolysaccharides; MAP Kinase Signaling System; Mice; Models, Molecular; Molecular Conformation; Molecular Docking Simulation; NF-kappa B; Norisoprenoids; Phosphorylation; Plant Extracts

Topics: Animals; Cyclohexanones; Disease Models, Animal; Glutathione; Humans; Hydrolases; Liver; Liver Regeneration; Medication Adherence; Mice; Mice, Knockout; NF-E2-Related Factor 2; Nitrobenzoates; Oxidative Stress; Oxidoreductases; Signal Transduction; Tyrosine; Tyrosinemias; Withholding Treatment

Topics: Anacardiaceae; Animals; Antimalarials; Belgium; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Flavonoids; HeLa Cells; Humans; Inhibitory Concentration 50; Malaria; Mice; Molecular Structure; Nuclear Magnetic Resonance, Biomolecular; Parasitic Sensitivity Tests; Plant Leaves; Plasmodium berghei; Plasmodium falciparum; Quercetin; Zebrafish

Topics: Animals; Anti-Bacterial Agents; Bacterial Proteins; Cyclohexanones; Disease Models, Animal; Gram-Positive Bacteria; Gram-Positive Bacterial Infections; Humans; Male; Methicillin-Resistant Staphylococcus aureus; Mice; Mice, Inbred BALB C; Peptides, Cyclic; Quorum Sensing; Signal Transduction; Staphylococcal Infections; Virulence Factors

Topics: Animals; Body Temperature; Cyclohexanones; Cyclohexylamines; Discrimination, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Illicit Drugs; Locomotion; Male; Mice; Phencyclidine; Rats; Rats, Sprague-Dawley; Reinforcement, Psychology; Self Administration; Substance Withdrawal Syndrome; Telemetry

Topics: Action Potentials; Analgesics; Animals; Animals, Genetically Modified; Cannabinoids; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Gene Expression Regulation; Glycine Agents; HEK293 Cells; Humans; In Vitro Techniques; Inflammation; Male; Mice; Mice, Inbred C57BL; Mutation; Neurons; Pain; Pain Measurement; Patch-Clamp Techniques; Receptors, Glycine; Reflex, Startle; Rotarod Performance Test; Spinal Cord; Strychnine; Time Factors; Transfection

Topics: Animals; Antifungal Agents; Caenorhabditis elegans; Candida albicans; Candidiasis; Cyclohexanones; Disease Models, Animal; Drug Resistance, Fungal; Female; Fluconazole; Humans; Mice; Microbial Sensitivity Tests

Topics: Animals; Benzamides; Biomarkers; Caspase 1; Caspase Inhibitors; Cell Line; Cyclohexanones; Disease Models, Animal; Humans; Inflammation; Interleukin-1beta; Macrophages; Models, Molecular; Nanoparticles; NF-kappa B; Particulate Matter; Potassium; Titanium

Topics: Administration, Oral; Albinism, Oculocutaneous; Animals; Blotting, Western; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Genotyping Techniques; Melanins; Melanosomes; Membrane Glycoproteins; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Microscopy, Electron, Transmission; Nitrobenzoates; Oxidoreductases; Real-Time Polymerase Chain Reaction; Treatment Outcome; Tyrosine

Topics: Adolescent; Alkaptonuria; Animals; Autopsy; Child; Clinical Trials as Topic; Compassionate Use Trials; Cyclohexanones; Disease Models, Animal; Disease Progression; Drug Approval; Endpoint Determination; Female; Homogentisic Acid; Humans; Infant; Male; Mice; National Health Programs; National Institutes of Health (U.S.); Nitrobenzoates; Observational Studies as Topic; Off-Label Use; Orphan Drug Production; Rare Diseases; Rats; Sample Size; Tyrosine; Tyrosinemias; United States; United States Food and Drug Administration

Topics: Animals; Benzamides; Cyclohexanones; Cytokines; Dermatitis, Atopic; Dinitrochlorobenzene; Disease Models, Animal; Epidermis; Female; Humans; Immunoglobulin E; Immunosuppressive Agents; Inflammation Mediators; Mast Cells; Mice; Mice, Inbred BALB C; Ointments; Oxazolone; Tacrolimus

Topics: Animals; Aqueous Humor; Benzamides; Cells, Cultured; Cyclohexanones; Disease Models, Animal; Immunohistochemistry; Male; NF-kappa B; Rats, Inbred Lew; Treatment Outcome; Uveitis

Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Chondrocytes; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Female; Humans; Joint Diseases; Knee Joint; Male; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitrobenzoates; Ochronosis

Topics: Animals; Benzylidene Compounds; Cyclohexanones; Disease Models, Animal; KATP Channels; Male; Mice; Mice, Inbred BALB C; Neuralgia; Receptors, Opioid, kappa; Signal Transduction

Topics: Animals; Bilirubin; Body Weight; Cyclohexanones; Disease Models, Animal; Hepatocytes; Hydrolases; Inflammation; Interleukin-22; Interleukins; Liver; Liver Failure; Male; Mice; Mice, Knockout; Neutrophils; Nitrobenzoates; Receptors, CCR2; Tyrosine

Topics: Animals; Anticonvulsants; Benzodioxoles; Cyclohexanones; Disease Models, Animal; Electroencephalography; Epilepsy, Temporal Lobe; Exploratory Behavior; Hindlimb Suspension; Hippocampus; Male; Maze Learning; Mice; Mice, Inbred C57BL; Neurodegenerative Diseases; Piperidines

Topics: Animals; Anoikis; Apoptosis Regulatory Proteins; Benzamides; Cell Line, Tumor; Cyclohexanones; Disease Models, Animal; Gene Expression; Genes, Reporter; Humans; Mice; Molecular Imaging; NF-kappa B; Pancreatic Neoplasms; Peritoneal Neoplasms; Protein Binding; Transcription Factor RelA; Tumor Burden; Xenograft Model Antitumor Assays

Topics: Alkaptonuria; Animals; Cyclohexanones; Disease Models, Animal; Genetic Therapy; Humans; Mice; Nitrobenzoates; Ochronosis; Treatment Outcome

Topics: Animals; Bone Marrow Cells; Bone Marrow Transplantation; Cell Fusion; Cyclohexanones; Disease Models, Animal; Female; Hepatocytes; Hydrolases; Interferon gamma Receptor; Interferon-gamma; Killer Cells, Natural; Liver Failure; Liver Regeneration; Male; Mice; Mice, Knockout; Monocytes; Nitrobenzoates; Protein Binding; Receptors, Interferon

Topics: Acyclic Monoterpenes; Adult; Alkenes; Animals; Annona; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Bicyclic Monoterpenes; Cell Line, Tumor; Cyclohexane Monoterpenes; Cyclohexanones; Disease Models, Animal; Drug Compounding; Gas Chromatography-Mass Spectrometry; Hep G2 Cells; Humans; Inhibitory Concentration 50; Male; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Monoterpenes; Oils, Volatile; Plant Leaves; Sesquiterpenes; Sesquiterpenes, Germacrane; Terpenes; Young Adult

Topics: Animals; Anti-Inflammatory Agents; Benzamides; Carboxymethylcellulose Sodium; Colitis; Colon; Cyclohexanones; Dextran Sulfate; Disease Models, Animal; Endocrine Cells; Male; NF-kappa B; Piperidones; Rats; Rats, Wistar; Transcription Factor AP-1

Topics: Animals; Behavior, Animal; Cyclohexanones; Disease Models, Animal; Hydrolases; Learning; Memory, Long-Term; Mice; Nitrobenzoates; Tyrosine; Tyrosinemias

Topics: Animals; Benzamides; Biomarkers; Body Weight; Chromogranin A; Colitis; Cyclohexanones; Disease Models, Animal; Endocrine Cells; Gene Expression; Inflammatory Bowel Diseases; Intestinal Mucosa; Male; NF-kappa B; Piperidones; Rats; Serotonin; Transcription Factor AP-1; Trinitrobenzenesulfonic Acid

Topics: Animals; Cyclohexanones; Disease Models, Animal; Genetic Therapy; Hepatocytes; Hydrolases; Immunohistochemistry; Liver; Nitrobenzoates; Swine; Transplantation, Homologous; Tyrosinemias

Topics: Animals; Cell Line; Cell Proliferation; CRISPR-Cas Systems; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Exons; Gene Editing; Genetic Therapy; Hepatocytes; Humans; Hydrolases; Liver; Metabolic Networks and Pathways; Mice; Mice, Inbred Strains; Mice, Knockout; Nitrobenzoates; Oxidoreductases; Phenotype; Tyrosinemias

Topics: Adenomatous Polyposis Coli; Animals; Benzamides; Cell Transformation, Neoplastic; Cyclohexanones; Disease Models, Animal; Gene Expression Regulation, Neoplastic; Humans; Intestinal Mucosa; Membrane Glycoproteins; Mice, Knockout; Mice, Transgenic; Neoplasms; NF-kappa B; Proteinase Inhibitory Proteins, Secretory; Signal Transduction

Topics: Animals; Antidepressive Agents; Behavior, Animal; Cyclohexanones; Depression; Disease Models, Animal; Inflammation; Male; Nerve Growth Factor; Neuronal Outgrowth; NF-E2-Related Factor 2; PC12 Cells; Phenanthrenes; Rats; Tumor Necrosis Factor-alpha

Topics: Animals; Apoptosis; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Cyclin-Dependent Kinase Inhibitor p21; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Hepatectomy; Hepatocytes; Hydrolases; Kidney Diseases, Cystic; Kidney Neoplasms; Kidney Tubules, Proximal; Liver Neoplasms; Liver Regeneration; Mice; Mice, Knockout; Neoplasms; Nitrobenzoates; Tyrosinemias

Topics: Animals; Anti-Inflammatory Agents; Benzamides; Cyclohexanones; Disease Models, Animal; Intestinal Diseases; Lung Diseases; Male; NF-kappa B; Rats; Rats, Sprague-Dawley; Reperfusion Injury

Topics: Animals; Antigen-Presenting Cells; Autoimmune Diseases; Benzamides; Cell Nucleus; Cyclohexanones; Cytokines; Disease Models, Animal; Down-Regulation; Female; Fluorescent Antibody Technique, Indirect; Injections, Intraperitoneal; Lymphocyte Activation; Mice; Microscopy, Confocal; Retina; Retinitis; T-Lymphocytes; Transcription Factor RelA; Uveitis

Topics: Animals; Benzamides; Cyclohexanones; Cytokines; Disease Models, Animal; Drug Screening Assays, Antitumor; Humans; Mice; Mice, Nude; Tumor Cells, Cultured; Urinary Bladder Neoplasms

Topics: Animals; Bilirubin; Biomarkers; Cell Proliferation; Cyclohexanones; Dependovirus; Disease Models, Animal; Genetic Therapy; Genetic Vectors; Hepatocytes; Hydrolases; Injections, Intravenous; L-Lactate Dehydrogenase; Liver; Liver Function Tests; Mice; Mice, Inbred BALB C; Mice, Knockout; Nitrobenzoates; Plasmids; Serum Albumin; Tail; Time Factors; Transfection; Tyrosinemias; Urea

Topics: Active Transport, Cell Nucleus; Administration, Topical; Animals; Benzamides; Cell Line; Cyclohexanones; Dermatitis, Atopic; Disease Models, Animal; Humans; Mice; NF-kappa B

Topics: Acetylcysteine; Animals; Antioxidants; Benzamides; Blindness; Burns, Chemical; Chemokine CCL2; Corneal Neovascularization; Cyclohexanones; Deuterium Oxide; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Eye Burns; Male; Mice; Mice, Inbred ICR; Mice, Knockout; Microscopy, Fluorescence; NF-kappa B; Oxidative Stress; Reactive Oxygen Species; Reverse Transcriptase Polymerase Chain Reaction; Sodium Hydroxide; Superoxide Dismutase; Superoxide Dismutase-1; Vascular Endothelial Growth Factor A

Topics: Acetylcysteine; Animals; Bipolar Disorder; Brain; Corpus Striatum; Cyclohexanones; Dextroamphetamine; Disease Models, Animal; Frontal Lobe; Glutathione; Male; Rats; Rats, Sprague-Dawley; Schizophrenia

Topics: Animals; Cell Survival; Cells, Cultured; Chromosomes; Cyclohexanones; Disease Models, Animal; Female; Fetus; Fibroblasts; Genetic Complementation Test; Genetic Therapy; Genetic Vectors; Humans; Hydrolases; Induced Pluripotent Stem Cells; Lentivirus; Liver; Mice; Mice, Knockout; Nitrobenzoates; Pregnancy; Promoter Regions, Genetic; Spleen Focus-Forming Viruses; Tetraploidy; Tyrosinemias

Topics: Acute Disease; Animals; Benzylidene Compounds; Cyclohexanones; Cytokines; Disease Models, Animal; Edema; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Inflammation; Inflammation Mediators; JNK Mitogen-Activated Protein Kinases; Lipopolysaccharides; Liver; Lung; Macrophages, Peritoneal; Male; Mice; NF-kappa B; Nitric Oxide; Phosphorylation; RNA, Messenger; Survival Analysis

Topics: Analgesics; Animals; Curcumin; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Inflammation; Inflammation Mediators; Inhibitory Concentration 50; Injections, Intraperitoneal; Male; Mice; Mice, Inbred BALB C; Naloxone; Narcotic Antagonists; Pain; Toxicity Tests, Acute

Topics: Albinism, Oculocutaneous; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Enzyme Stability; Eye Color; Female; Humans; Melanins; Melanocytes; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Microscopy, Electron, Transmission; Models, Molecular; Monophenol Monooxygenase; Mutation; Nitrobenzoates; Pregnancy; Skin Pigmentation; Tyrosine

Topics: Amino Acid Substitution; Amyotrophic Lateral Sclerosis; Animals; Blood-Brain Barrier; Cyclohexanones; Cyclopropanes; Disease Models, Animal; Humans; Mice; Mice, Transgenic; Mutation; Neurons; PC12 Cells; Phenyl Ethers; Rats; Superoxide Dismutase; Superoxide Dismutase-1

Topics: Airway Remodeling; Animals; Asthma; Benzamides; Bronchoalveolar Lavage Fluid; Cells, Cultured; Cyclohexanones; Cytokines; Disease Models, Animal; Eosinophils; Epithelial Cells; Female; Humans; Inflammation; Inflammation Mediators; Leukocytes, Mononuclear; Mice; Mice, Inbred BALB C; NF-kappa B; Respiratory Hypersensitivity

Topics: Adenocarcinoma; Animals; Antimetabolites, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Blotting, Western; Cell Movement; Cell Proliferation; Cyclohexanones; Deoxycytidine; Disease Models, Animal; Fluorescent Antibody Technique; Gemcitabine; Humans; Immunoenzyme Techniques; Interleukin-8; Liver Neoplasms; Matrix Metalloproteinase 9; Mice; Mice, Nude; NF-kappa B; Pancreatic Neoplasms; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Cells, Cultured

Topics: Animals; Case-Control Studies; Cimetidine; Cyclohexane Monoterpenes; Cyclohexanones; Disease Models, Animal; Disulfiram; Enzyme Inhibitors; Female; Hedeoma; Liver Diseases; Mentha pulegium; Mice; Mice, Inbred BALB C; Monoterpenes; Oils, Volatile

Topics: Animals; Caspase 3; Caspase 9; Caspases; Cyclohexanones; Disease Models, Animal; DNA Fragmentation; Enzyme Inhibitors; Hepatocytes; Homogentisic Acid; Hydrolases; In Situ Nick-End Labeling; Kidney Tubules, Proximal; Mice; Mice, Knockout; Nitrobenzoates; Survival Rate; Tyrosine; Tyrosinemias

Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-X Protein; Benzamides; Calcium-Binding Proteins; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 3; Caspase 8; Caspase 9; Caspases; Cell Line, Tumor; Cyclin D; Cyclin D1; Cyclins; Cyclohexanones; Disease Models, Animal; Down-Regulation; Enzyme Activation; Humans; Intracellular Signaling Peptides and Proteins; Membrane Glycoproteins; Mice; Mice, Inbred NOD; Mice, SCID; Multiple Myeloma; Nerve Tissue Proteins; NF-kappa B; Proto-Oncogene Proteins c-bcl-2; Synaptotagmin I; Synaptotagmins; Translocation, Genetic; Vascular Endothelial Growth Factor A

Topics: Animals; Antineoplastic Agents; Apoptosis; Base Sequence; Benzamides; Binding Sites; Cell Division; Cell Line, Tumor; Consensus Sequence; Cyclohexanones; Disease Models, Animal; Human T-lymphotropic virus 1; Humans; Leukemia-Lymphoma, Adult T-Cell; Mice; NF-kappa B; Transplantation, Heterologous

Topics: Albumins; Animals; Antineoplastic Agents; Benzamides; Body Mass Index; Body Weight; Cachexia; Cell Line, Tumor; Cyclohexanones; Disease Models, Animal; Dose-Response Relationship, Drug; Hematocrit; Humans; Interleukin-6; Male; Mice; Mice, Inbred BALB C; Muscle, Skeletal; Neoplasm Transplantation; NF-kappa B; Prostatic Neoplasms; Time Factors; Triglycerides; Weight Loss

Topics: Animals; Arthritis, Experimental; Benzamides; Cell Nucleus; Cell Proliferation; Cells, Cultured; Cyclohexanones; Disease Models, Animal; Hindlimb; Humans; Injections, Subcutaneous; Male; Mice; Mice, Inbred DBA; NF-kappa B; RNA, Messenger; Synovial Membrane; Translocation, Genetic

Topics: Animals; Animals, Newborn; Antioxidants; Ascorbic Acid; Carcinoma, Hepatocellular; Cyclohexanones; Disease Models, Animal; Drug Therapy, Combination; Female; Glutathione; Hydrolases; Liver Neoplasms; Mice; Mice, Knockout; Nitrobenzoates; Oxidative Stress; Pregnancy; Tyrosinemias

Topics: Animals; bcl-X Protein; Carcinoma, Hepatocellular; Cyclohexanones; Disease Models, Animal; Hydrolases; Liver Neoplasms; Mice; Mice, Knockout; Nitrobenzoates; Proto-Oncogene Proteins c-akt; Proto-Oncogene Proteins c-bcl-2; Signal Transduction; Tyrosinemias

Topics: alpha-Fetoproteins; Amino Acid Metabolism, Inborn Errors; Amino Acids; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Female; Heptanoates; Humans; Hydrolases; Liver; Liver Diseases; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Nitrobenzoates; Pancreas; RNA, Messenger; Tyrosine

Topics: Amino Acid Metabolism, Inborn Errors; Animals; Cell Count; Cell Transplantation; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Genetic Therapy; Humans; Hydrolases; Immunoenzyme Techniques; Liver; Liver Function Tests; Liver Neoplasms; Male; Mice; Mice, Inbred C57BL; Nitrobenzoates; Retroviridae; Tyrosine

Topics: Amino Acid Metabolism, Inborn Errors; Animals; Base Sequence; Cell Survival; Cell Transplantation; Cells, Cultured; Cyclohexanones; Disease Models, Animal; DNA, Complementary; Enzyme Inhibitors; Female; Genetic Diseases, Inborn; Genetic Therapy; Humans; Hydrolases; Liver; Male; Mice; Molecular Sequence Data; Nitrobenzoates; Tyrosine

Topics: 4-Hydroxyphenylpyruvate Dioxygenase; Alkaptonuria; Animals; Cyclohexanones; Disease Models, Animal; Enzyme Inhibitors; Homogentisic Acid; Mice; Mice, Mutant Strains; Nitrobenzoates

Topics: Animals; Cyclohexanones; Diet; Disease Models, Animal; Enzyme Inhibitors; Hydrolases; Mice; Mice, Knockout; Nitrobenzoates; Phenylalanine; Tyrosine; Tyrosinemias